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Effect of using different fundus cameras and image resolutions on automatic measurements of retinal vascular parameters.

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Τίτλος: Effect of using different fundus cameras and image resolutions on automatic measurements of retinal vascular parameters.
Συγγραφείς: Cunnac P; Department of Ophthalmology, Grenoble-Alpes University Hospital, Grenoble cedex 09, France.; Grenoble-Alpes University, INSERM U1300, Laboratory, Grenoble, HP2, France., Boussat B; Department of Public Health, University Hospital of Grenoble-Alpes, Grenoble-Alpes , France., Hogg S; School of Science and Engineering, VAMPIRE project, University of Dundee, Computing, Dundee, UK., Geiser M; System engineering institute, HES-SO, Sion, Switzerland., MacGillivray T; VAMPIRE project, Centre for Clinical Brain Sciences, University of Edinburgh, Edinburgh, UK., Trucco E; School of Science and Engineering, VAMPIRE project, University of Dundee, Computing, Dundee, UK., Chiquet C; Department of Ophthalmology, Grenoble-Alpes University Hospital, Grenoble cedex 09, France. christophe.chiquet@inserm.fr.; Grenoble-Alpes University, INSERM U1300, Laboratory, Grenoble, HP2, France. christophe.chiquet@inserm.fr.; Department of Ophthalmology, Grenoble Alpes University Hospital, CS 10217, Grenoble cedex09, 38043, France. christophe.chiquet@inserm.fr.
Πηγή: Scientific reports [Sci Rep] 2026 Mar 21; Vol. 16 (1). Date of Electronic Publication: 2026 Mar 21.
Τύπος έκδοσης: Journal Article
Γλώσσα: English
Στοιχεία περιοδικού: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE
Imprint Name(s): Original Publication: London : Nature Publishing Group, copyright 2011-
Ιατρικοί όροι (MeSH): Retinal Vessels*/diagnostic imaging , Image Processing, Computer-Assisted*/methods , Fundus Oculi*, Humans ; Software ; Female ; Male ; Adult
Περίληψη: Morphological measurements of retinal vessel parameters are commonly obtained from fundus images using semi-automatic software packages. Since image quality, and image processing methods are potential sources of variation of such measurements, the aim of this study was to determine quantitatively the effect of using different fundus cameras and image resolutions on measurements of retinal vascular parameters. Fifty-four digital fundus images of 27 healthy subjects were acquired using two non-mydriatic cameras, Topcon TRC NW6S and Canon CR-2. Central retinal artery and vein equivalent (CRAE, CRVE), arteriolar and venular tortuosity (TortA and TortV) and fractal dimension (FD) were calculated using VAMPIRE software. First, VAMPIRE measurements were compared between Topcon images (3008 × 2000 pixels) and Canon images after resizing manually (CR2r, 3008 × 2000 px). The effect of different resolutions was studied using Canon images at full resolution (4147 × 2764 px, 100%) and then scaled at 83.8%, 75% and 50% in JPEG format using the dedicated Canon software. When comparing images acquired by CR2r and Topcon at the same resolution, all parameters were significantly affected. When using images with different resolutions from the same camera, significant increases of CRAE and CRVE and significant decreases of FD were found for decreasing resolutions. In conclusion, vascular measurements from images from different fundus cameras or at different resolutions are not, in general, directly comparable.
(© 2026. The Author(s).)
Competing Interests: Declarations. Competing interests: The authors declare no competing interests.
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Contributed Indexing: Keywords: Fundus photographs; Retina; Retinal image analysis; Retinal microvasculature; Retinal vascular measurements; Retinal vessel calibers
Entry Date(s): Date Created: 20260322 Date Completed: 20260711 Latest Revision: 20260711
Update Code: 20260711
PubMed Central ID: PMC13144359
DOI: 10.1038/s41598-026-44196-y
PMID: 41865048
Βάση Δεδομένων: MEDLINE
Περιγραφή
ISSN:2045-2322
DOI:10.1038/s41598-026-44196-y