Academic Journal
Systematic review and meta-analysis of the safety and efficacy of transvenous lead extraction in octogenarian patients.
| Τίτλος: | Systematic review and meta-analysis of the safety and efficacy of transvenous lead extraction in octogenarian patients. |
|---|---|
| Συγγραφείς: | Drożdż G; Department of General Internal Medicine, HOCH Ostschweiz, St. Gallen, Switzerland., Doroszko A; Division of Cardiology, Centre for Heart Diseases, 4th Military Clinical Hospital, Wrocław, Poland.; Faculty of Medicine, Wroclaw University of Science and Technology, Wrocław, Poland., Banasiak W; Division of Cardiology, Centre for Heart Diseases, 4th Military Clinical Hospital, Wrocław, Poland.; Faculty of Medicine, Wroclaw University of Science and Technology, Wrocław, Poland., Sobieszczańska M; Clinical Department of Geriatrics and Internal Diseases, Wroclaw Medical University, Wrocław, Poland., Ptaszkowski K; University Centre of Physiotherapy and Rehabilitation, Wroclaw Medical University, Wrocław, Poland., Jagielski D; Division of Cardiology, Centre for Heart Diseases, 4th Military Clinical Hospital, Wrocław, Poland.; Faculty of Medicine, Wroclaw University of Science and Technology, Wrocław, Poland. |
| Πηγή: | Polish archives of internal medicine [Pol Arch Intern Med] 2026 Apr 29; Vol. 136 (4). Date of Electronic Publication: 2026 Mar 05. |
| Τύπος έκδοσης: | Journal Article; Systematic Review; Meta-Analysis |
| Γλώσσα: | English |
| Στοιχεία περιοδικού: | Publisher: Medycyna Praktyczna Country of Publication: Poland NLM ID: 101700960 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1897-9483 (Electronic) Linking ISSN: 00323772 NLM ISO Abbreviation: Pol Arch Intern Med Subsets: MEDLINE |
| Imprint Name(s): | Original Publication: Liszki, Poland : Medycyna Praktyczna, [2017]- |
| Ιατρικοί όροι (MeSH): | Device Lead Extraction*/methods , Pacemaker, Artificial* , Defibrillators, Implantable*, Humans ; Aged, 80 and over ; Treatment Outcome ; Female ; Male ; Age Factors |
| Περίληψη: | Introduction: As the global population ages and the use of cardiac implantable electronic devices (CIEDs) increases, transvenous lead extraction (TLE) is being performed more frequently in elderly patients. Concerns remain regarding its safety and efficacy in octogenarians, and age‑specific recommendations are limited. Objectives: We aimed to assess procedural success, complication rates, and mortality associated with TLE in patients aged 80 years or older in comparison with younger individuals. Patients and Methods: A systematic search of PubMed, Cochrane CENTRAL, SciELO, and ScienceDirect was conducted up to December 2024. Studies reporting TLE outcomes in octogenarians and younger patients were included according to predefined criteria. A meta‑analysis was performed to compare procedural success, complications, and mortality between the age groups. Results: Seventeen studies including 15 984 patients were analyzed. Complete lead extraction success was 96.7% in octogenarians and 96.2% in the patients aged below 80 years. No significant differences were observed in major or minor procedural complications. In‑hospital mortality was low and comparable between the groups. Although long‑term mortality was higher in the octogenarians, this reflected greater baseline comorbidity and frailty rather than increased procedural risk. None of the included studies demonstrated higher periprocedural danger of TLE in elderly patients. Conclusions: TLE is safe and effective in patients aged 80 years and older, with outcomes comparable to younger individuals. Advanced age alone should not preclude referral for lead extraction. |
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| Entry Date(s): | Date Created: 20260311 Date Completed: 20260710 Latest Revision: 20261011 |
| Update Code: | 20261012 |
| DOI: | 10.20452/pamw.17246 |
| PMID: | 41811213 |
| Βάση Δεδομένων: | MEDLINE |
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