Academic Journal
Are there disparities in cerebral sinus venous thrombosis between the Arab and Jewish populations in Israel - a multicenter cohort study?
| Τίτλος: | Are there disparities in cerebral sinus venous thrombosis between the Arab and Jewish populations in Israel - a multicenter cohort study? |
|---|---|
| Συγγραφείς: | Molad J; Department of Neurology & Stroke, Tel-Aviv Sourasky Medical Center, Tel-Aviv, Israel; Faculty of Medicine, Tel-Aviv University, Tel-Aviv, Israel., Honig A; Department of Neurology, Soroka Medical Center, Beer-Sheva, Israel., Hallevi H; Department of Neurology & Stroke, Tel-Aviv Sourasky Medical Center, Tel-Aviv, Israel; Faculty of Medicine, Tel-Aviv University, Tel-Aviv, Israel., Metanis I; Departments of Neurology, Hadassah-Hebrew University Medical Center, Jerusalem, Israel., Mendel R; Department of Neurology, Assuta Medical Center, Ashdod, Israel., Barnea R; Department of Neurology, Rabin Medical Center, Petach-Tikva, Israel., Auriel E; Faculty of Medicine, Tel-Aviv University, Tel-Aviv, Israel; Department of Neurology, Rabin Medical Center, Petach-Tikva, Israel., Naftali J; Department of Neurology, Rabin Medical Center, Petach-Tikva, Israel., Aladdin S; Departments of Neurology, Sheba Medical Center, Ramat-Gan, Israel., Orion D; Departments of Neurology, Sheba Medical Center, Ramat-Gan, Israel., Peretz S; Department of Neurology, Shamir Medical Center, Zrifin, Israel., Wiegler KB; Department of Neurology, Ziv Medical Center, Safed, Israel., Leker RR; Departments of Neurology, Hadassah-Hebrew University Medical Center, Jerusalem, Israel., Simaan N; Department of Neurology, Ziv Medical Center, Safed, Israel; The Azrieli Faculty of Medicine, Safed, Bar Ilan University's, Safed, Israel. Electronic address: naaem.simaan@gmail.com. |
| Συλλογικό Έργο: | Israeli CSVT Consortium |
| Πηγή: | Journal of the neurological sciences [J Neurol Sci] 2026 May 15; Vol. 484, pp. 125844. Date of Electronic Publication: 2026 Feb 27. |
| Τύπος έκδοσης: | Journal Article; Multicenter Study |
| Γλώσσα: | English |
| Στοιχεία περιοδικού: | Publisher: Elsevier Country of Publication: Netherlands NLM ID: 0375403 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1878-5883 (Electronic) Linking ISSN: 0022510X NLM ISO Abbreviation: J Neurol Sci Subsets: MEDLINE |
| Imprint Name(s): | Original Publication: Amsterdam : Elsevier, <19 -> |
| Ιατρικοί όροι (MeSH): | Sinus Thrombosis, Intracranial*/ethnology , Sinus Thrombosis, Intracranial*/epidemiology , Arabs* , Jews*, Israel/epidemiology ; Israel/ethnology ; Humans ; Male ; Female ; Adult ; Retrospective Studies ; Middle Aged ; Cohort Studies ; Risk Factors ; Young Adult ; Middle Eastern People |
| Περίληψη: | Objective: Cerebral sinus venous thrombosis (CSVT) is a rare stroke subtype and data regarding the impact of ethnicity on its presentation and outcomes are limited. Methods: The Israeli CSVT cohort, which includes databases from six academic medical centers, was retrospectively studied. Demographics, clinical presentations, risk factors, radiological findings, and outcome parameters were compared between Jewish and Arab Israeli patients. Results: The study included 554 patients with CSVT, of whom 71 (13%) were of Arab ethnicity and 483 (87%) were Jewish. Arab patients were younger (mean age 38.4 ± 15.8 vs. 42.8 ± 10.1 years, p = 0.027), and more frequently male (48% vs. 33%, p = 0.013). Rates of Behcet's disease (BD) were higher among Arabs patients (13% vs. 3%, p < 0.001), antiphospholipid syndrome (23% vs. 10%, p = 0.002) and any coagulopathy (48% vs. 35%, p = 0.04), but lower rates of hypertension (4% vs. 15%, p = 0.016), and use of oral contraceptives (9% vs. 26%, p = 0.002). Differences in clinical presentation included higher rates of headache (90% vs. 74%, p = 0.004) and vomiting (39% vs. 15%, p < 0.001) in the Arab patient group. Arab ethnicity was associated with lower rates of any recanalization (aOR 0.346 [0.172-0.695], p = 0.003), and complete recanalization (aOR 0.408 [0.209-0.795], p = 0.008). Despite these differences, rates of favorable outcomes, mortality, and CSVT recurrence were similar between the groups. Conclusions: The findings highlight notable ethnic variations in the risk factors and clinical manifestations of CSVT between Arab and Jewish populations living in the same physical surroundings. Understanding these ethnic differences is crucial for creating targeted prevention and treatment strategies that cater to the specific needs of these diverse groups. (Copyright © 2026. Published by Elsevier B.V.) |
| Contributed Indexing: | Keywords: Cerebral sinus venous thrombosis; Ethnicity; Outcomes; Risk factors |
| Entry Date(s): | Date Created: 20260311 Date Completed: 20260710 Latest Revision: 20260713 |
| Update Code: | 20260713 |
| DOI: | 10.1016/j.jns.2026.125844 |
| PMID: | 41807916 |
| Βάση Δεδομένων: | MEDLINE |
καταχωρήστε σχόλιο πρώτοι!