A multimodal feature fusion with deep representation learning approach for polycystic ovary syndrome diagnosis using ultrasound images.

Bibliographic Details
Title: A multimodal feature fusion with deep representation learning approach for polycystic ovary syndrome diagnosis using ultrasound images.
Authors: Kranthi S; Department of Information Technology, Siddhartha Academy of Higher Education, Deemed to be University Vijayawada, Kanuru, 520007, Andhra Pradesh, India., Sandeep Y; Department of Information Technology, Siddhartha Academy of Higher Education, Deemed to be University Vijayawada, Kanuru, 520007, Andhra Pradesh, India., Pranathi K; Department of Information Technology, Siddhartha Academy of Higher Education, Deemed to be University Vijayawada, Kanuru, 520007, Andhra Pradesh, India., Laxmi Lydia E; Department of Computer Science and Engineering, Vignan's Institute of Engineering for Women, Visakhapatnam, 530046, India., Joshi GP; Department Electronic and AI System Engineering, Kangwon National University, Samcheok, 25913, Republic of Korea. joshi@kangwon.ac.kr., Cho W; Department Electronic and AI System Engineering, Kangwon National University, Samcheok, 25913, Republic of Korea. wcho@kangwon.ac.kr.
Source: Scientific reports [Sci Rep] 2026 Feb 20; Vol. 16 (1). Date of Electronic Publication: 2026 Feb 20.
Publication Type: Journal Article
Language: English
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE
Imprint Name(s): Original Publication: London : Nature Publishing Group, copyright 2011-
MeSH Terms: Polycystic Ovary Syndrome*/diagnostic imaging , Polycystic Ovary Syndrome*/diagnosis , Image Processing, Computer-Assisted*/methods , Deep Learning*, Ultrasonography/methods ; Ovary/diagnostic imaging ; Female ; Humans
Abstract: Nowadays, polycystic ovary syndrome (PCOS) is among the very first causes of female infertility, which is a hormone imbalance that affects women of childbearing age. The earlier diagnosis of many cysts using ovarian ultrasound image scans is the most predictable technique to make a precise identification of PCOS and to make a proper treatment plan to cure patients with this disorder. Nevertheless, the analysis depends on Rotterdam conditions, comprising a higher level of androgen hormones, polycystic ovaries, and ovulation failure on the ultrasound images. Nowadays, radiologists and physicians manually execute PCOS identification using ovarian ultrasound by calculating the follicle counts and defining their volume in the ovaries, which is the most challenging PCOS diagnostic condition. Still, the conventional processes used for identifying PCOS using computer-based methods depend on numerous image processing methods and then classic machine learning (ML) tactics for image classification, which is a repetitive procedure with comparatively lower performance. Currently, some scholars have applied deep learning (DL) techniques to discover PCOS from ultrasound images. In this manuscript, a Multi-Model Feature Engineering and Deep Learning for Diagnosis of Polycystic Ovary Syndrome (MMFEDL-DPCOS) model is proposed. The MMFEDL-DPCOS model aims to analyse and diagnose PCOS employing ultrasound images for a precise and pre-diagnosis stage. Primarily, the Gaussian filtering (GF) method is utilized in the image pre-processing phase for enhancing image quality by reducing the noise. Furthermore, the fusion of InceptionResNetv2, EfficientNetV2B3, VGG16, ResNet-50, and Inception‐V3 methods is employed for feature extraction. Finally, the regularized stacked autoencoder (RSAE) methodology is utilized for classification. The comparison analysis of the MMFEDL-DPCOS methodology portrayed a superior accuracy value of 98.68% over existing models under the PCOS dataset.
Competing Interests: Declarations. Competing interests: The authors declare no competing interests. Ethics approval: This article does not contain any studies with human participants performed by any of the authors. Consent to participate: Not applicable. Informed consent: Not applicable.
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Contributed Indexing: Keywords: Deep Learning; Feature Engineering; Image Pre-processing; Polycystic Ovary Syndrome Diagnosis; Ultrasound Image
Entry Date(s): Date Created: 20260220 Date Completed: 20260628 Latest Revision: 20260628
Update Code: 20260628
PubMed Central ID: PMC13022374
DOI: 10.1038/s41598-026-40718-w
PMID: 41721030
Database: MEDLINE
Description
ISSN:2045-2322
DOI:10.1038/s41598-026-40718-w