Academic Journal
Effects of solar-simulated (UVB plus UVA) radiation on the skin microbiome: An exploratory study.
| Τίτλος: | Effects of solar-simulated (UVB plus UVA) radiation on the skin microbiome: An exploratory study. |
|---|---|
| Συγγραφείς: | Dimmers F; IUF - Leibniz-Research Institute for Environmental Medicine, Duesseldorf, Germany.; Department of Dermatology, HELIOS Klinikum Krefeld, Academic Teaching Hospital of the University of Aachen, Aachen, Germany., Reichert D; IUF - Leibniz-Research Institute for Environmental Medicine, Duesseldorf, Germany., Wigmann C; IUF - Leibniz-Research Institute for Environmental Medicine, Duesseldorf, Germany., Trullàs C; Innovation and Development, ISDIN, Barcelona, Spain., Piquero-Casals J; Department of Dermatology, Dermik Multidisciplinary Dermatology Clinic, Barcelona, Spain., Brown A; Innovation and Development, ISDIN, Barcelona, Spain., Foyaca M; Innovation and Development, ISDIN, Barcelona, Spain., Esser C; IUF - Leibniz-Research Institute for Environmental Medicine, Duesseldorf, Germany., Krutmann J; IUF - Leibniz-Research Institute for Environmental Medicine, Duesseldorf, Germany. |
| Πηγή: | Photochemistry and photobiology [Photochem Photobiol] 2026 Sep-Oct; Vol. 102 (5), pp. 1150-1158. Date of Electronic Publication: 2026 Jan 29. |
| Τύπος έκδοσης: | Journal Article |
| Γλώσσα: | English |
| Στοιχεία περιοδικού: | Publisher: American Society for Photobiology Country of Publication: United States NLM ID: 0376425 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1751-1097 (Electronic) Linking ISSN: 00318655 NLM ISO Abbreviation: Photochem Photobiol Subsets: MEDLINE |
| Imprint Name(s): | Publication: <2004->: Lawrence KS : American Society for Photobiology Original Publication: Augusta, GA: American Society for Photobiology, <1996-> |
| Ιατρικοί όροι (MeSH): | Skin Microbiome*/radiation effects , Skin*/microbiology , Skin*/radiation effects , Microbiota*/radiation effects , Ultraviolet Rays*, Humans ; Male ; Adult ; Young Adult ; Sunlight |
| Περίληψη: | This exploratory in vivo study investigated the impact of solar-simulated ultraviolet (UV) radiation (UVB plus UVA) on the composition of the human skin microbiome in healthy male volunteers. Thirty Caucasian men were exposed to suberythemal and erythemal doses of UV radiation (0.5, 0.7, and 1.0 minimal erythema dose, MED) on defined areas of the lower back. Skin swabs were collected from both irradiated (n = 243) and nonirradiated control sites (n = 81) 30 min, 24 h, and 96 h postexposure. The microbial profiles were generated using flow cytometry, and the data were analyzed via the open-access bioinformatic platform FlowSoFine™. The results revealed pronounced alterations in the microbial composition, with changes already detectable 30 min after exposure. Although partial recovery was observed over time, certain microbial shifts persisted. Further analysis indicated dose-dependent trends in microbiome changes, suggesting a potential relationship between the extent of microbial alteration and the applied UV dose. These results suggest that even low, nonerythematous exposure to solar-simulated UV radiation can rapidly alter the microbial balance of the skin and emphasize the role of UV radiation as a potent modulator of the skin microbial homeostasis. (© 2026 The Author(s). Photochemistry and Photobiology published by Wiley Periodicals LLC on behalf of American Society for Photobiology.) |
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| Grant Information: | ISDIN, Barcelona, Spain |
| Contributed Indexing: | Keywords: UVA; UVB; flow cytometry; human skin; in vivo; skin microbiome |
| Entry Date(s): | Date Created: 20260129 Date Completed: 20260915 Latest Revision: 20260917 |
| Update Code: | 20260917 |
| PubMed Central ID: | PMC13575714 |
| DOI: | 10.1111/php.70078 |
| PMID: | 41612130 |
| Βάση Δεδομένων: | MEDLINE |
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