Academic Journal
Genome-wide association study (GWAS) identifies genetic loci controlling Distinctness, Uniformity, and Stability (DUS) traits in wheat.
| Τίτλος: | Genome-wide association study (GWAS) identifies genetic loci controlling Distinctness, Uniformity, and Stability (DUS) traits in wheat. |
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| Συγγραφείς: | Zanella CM; Niab, Park Farm, Villa Road, Histon, Cambridge, CB24 9NZ, UK., Horsnell R; Niab, Park Farm, Villa Road, Histon, Cambridge, CB24 9NZ, UK., Love B; Niab, Park Farm, Villa Road, Histon, Cambridge, CB24 9NZ, UK., Wright TIC; Niab, Park Farm, Villa Road, Histon, Cambridge, CB24 9NZ, UK., Taferner-Kriegl J; Austrian Agency for Health and Food Safety (AGES), Spargelfeldstraße 191, 1220, Vienna, Austria., Flamm C; Austrian Agency for Health and Food Safety (AGES), Spargelfeldstraße 191, 1220, Vienna, Austria., Andreani L; Council for Agricultural Research and Economics - Research Centre for Plant Protection and Certification, Tavazzano, LO, Italy., Delogu C; Council for Agricultural Research and Economics - Research Centre for Plant Protection and Certification, Tavazzano, LO, Italy., McMillan V; Niab, Park Farm, Villa Road, Histon, Cambridge, CB24 9NZ, UK., Wallace M; Niab, Park Farm, Villa Road, Histon, Cambridge, CB24 9NZ, UK., Scott E; Niab, Park Farm, Villa Road, Histon, Cambridge, CB24 9NZ, UK., Cockram J; Niab, Park Farm, Villa Road, Histon, Cambridge, CB24 9NZ, UK. james.cockram@niab.com. |
| Πηγή: | TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik [Theor Appl Genet] 2026 Jan 28; Vol. 139 (2), pp. 49. Date of Electronic Publication: 2026 Jan 28. |
| Τύπος έκδοσης: | Journal Article |
| Γλώσσα: | English |
| Στοιχεία περιοδικού: | Publisher: Springer Country of Publication: Germany NLM ID: 0145600 Publication Model: Electronic Cited Medium: Internet ISSN: 1432-2242 (Electronic) Linking ISSN: 00405752 NLM ISO Abbreviation: Theor Appl Genet Subsets: MEDLINE |
| Imprint Name(s): | Original Publication: Berlin, New York, Springer |
| Ιατρικοί όροι (MeSH): | Triticum*/genetics , Genome-Wide Association Study* , Quantitative Trait Loci*, Phenotype ; Genetic Markers ; Genotype ; Chromosome Mapping ; Polymorphism, Single Nucleotide ; Genome, Plant ; Plant Breeding ; Genetic Association Studies |
| Περίληψη: | Key Message: Genetic analysis of wheat Distinctness, Uniformity, and Stability (DUS) characteristics identifies significant marker-trait associations for 15 DUS traits, including associations for 'seed: colouration with phenol' closely linked to Ppo-A1. Crop improvement via breeding underpins the yield gains required for future food security. Commercial development of new varieties is supported by the legal protection afforded by Plant Variety Rights, which for wheat is awarded via evaluation of 27 morphological 'characteristics' as part of Distinctness, Uniformity, and Stability (DUS) testing. While identification of molecular markers predictive for wheat DUS characteristics would be useful to aid processes such as variety identification and DUS test optimization, little is known about their genetic control. Here we assemble a panel of 412 European wheat varieties, along with corresponding DUS phenotypic data and genotype using the TaNG 43k genotyping array. The resulting 14,921 polymorphic genetic markers were distributed approximately evenly between the A (33%), B (38%), and D (29%) wheat sub-genomes. DUS characteristic heritability (h2) varied (mean = 0.44), ranging from 0.27 ('ear: glaucosity') to 1.00 ('ear: scurs or awns'). Subsequent genome-wide association study (GWAS) identified significant marker-trait associations for 15 of the 24 DUS characteristics analysed, resolved into 57 genetic loci. Of note, a highly significant association (- log (© 2026. The Author(s).) |
| Competing Interests: | Declarations. Competing interests: Following Theoretical and Applied Genetics (TAG) guidelines, we declare that James Cockram is a member of the TAG Editorial Board. The authors declare no other competing interests. |
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| Grant Information: | SEP-210522318 HORIZON EUROPE Framework Programme |
| Substance Nomenclature: | 0 (Genetic Markers) |
| Entry Date(s): | Date Created: 20260128 Date Completed: 20260701 Latest Revision: 20260920 |
| Update Code: | 20260920 |
| PubMed Central ID: | PMC12852309 |
| DOI: | 10.1007/s00122-025-05130-4 |
| PMID: | 41603983 |
| Βάση Δεδομένων: | MEDLINE |
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