Academic Journal
Mechanics-Oriented Coil Size Selection for an Internal Carotid Aneurysm With Fluid-Structure Interaction.
| Τίτλος: | Mechanics-Oriented Coil Size Selection for an Internal Carotid Aneurysm With Fluid-Structure Interaction. |
|---|---|
| Συγγραφείς: | Han J; College of Sciences, Xi'an University of Science and Technology, Xi'an, China., Zhao N; Cangzhou Hospital of Integrated Traditional Chinese and Western Medicine of Hebei Province, Cangzhou, China., Li W; The Second Affiliated Hospital of Shaanxi University of Chinese Medicine, Xianyang, China., Zhao S; School of Aeronautic Science and Engineering, Beihang University, Beijing, China. |
| Πηγή: | International journal for numerical methods in biomedical engineering [Int J Numer Method Biomed Eng] 2026 Jan; Vol. 42 (1), pp. e70139. |
| Τύπος έκδοσης: | Journal Article |
| Γλώσσα: | English |
| Στοιχεία περιοδικού: | Publisher: Wiley Country of Publication: England NLM ID: 101530293 Publication Model: Print Cited Medium: Internet ISSN: 2040-7947 (Electronic) Linking ISSN: 20407939 NLM ISO Abbreviation: Int J Numer Method Biomed Eng Subsets: MEDLINE |
| Imprint Name(s): | Original Publication: [Oxford, UK] : Wiley |
| Ιατρικοί όροι (MeSH): | Carotid Artery, Internal*/physiopathology , Aneurysm*/physiopathology , Aneurysm*/therapy , Intracranial Aneurysm*/physiopathology, Hemodynamics/physiology ; Blood Flow Velocity/physiology ; Humans ; Stress, Mechanical ; Hydrodynamics ; Computer Simulation ; Models, Cardiovascular |
| Περίληψη: | The coil intervention is a common aneurysm treatment strategy, but the effect of coil size on aneurysm hemodynamics and mechanics is not fully understood. In this paper, how different sizes of coils affect the hemodynamic and mechanical properties of a real internal carotid artery (ICA) aneurysm was investigated. A fluid-structure interaction (FSI) method based on the Arbitrary Lagrangian-Eulerian (ALE) approach was used to consider non-Newtonian blood flow, linear elastic arterial wall and simulations. It is indicated that with the increase of coil size, the hemodynamic parameters related to aneurysm such as wall shear stress (WSS), time-averaged WSS (TAWSS) and oscillatory shear index (OSI) decreased significantly. However, too large coils will compress the parent artery, produce high TAWSS areas in adjacent branches, and cause stress concentration on the aneurysm wall. Moreover, both the average displacement and von Mises stress of the aneurysm dome initially decrease and then increase with coil size. The appropriate size of the coil is beneficial to minimize displacement and stress by reducing blood flow velocity and vortices. The effects of different coil sizes were predicted by computational fluid dynamics (CFD), and the individualized treatment plan was adjusted according to the aneurysm morphology and hemodynamic characteristics. Our results provide a new theoretical basis for interventional therapy and help to promote the transformation of coil intervention from empirical filling to mechanics-oriented precision treatment. (© 2026 John Wiley & Sons Ltd.) |
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| Grant Information: | T2288101 National Natural Science Foundation of China; 52202430 National Natural Science Foundation of China; 92371201 National Natural Science Foundation of China; 2024JC-YBQN-0008 Natural Science Foundation of Shaanxi Province |
| Contributed Indexing: | Keywords: coil interventional therapy; fluid–structure interaction; hemodynamics; internal carotid artery aneurysms; non‐Newtonian fluid incompressible flow |
| Entry Date(s): | Date Created: 20260114 Date Completed: 20260626 Latest Revision: 20260626 |
| Update Code: | 20260627 |
| DOI: | 10.1002/cnm.70139 |
| PMID: | 41532356 |
| Βάση Δεδομένων: | MEDLINE |
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