Academic Journal

Associations between ocular surface parameters, contrast sensitivity, and higher-order aberrations in computer vision syndrome.

Bibliographic Details
Title: Associations between ocular surface parameters, contrast sensitivity, and higher-order aberrations in computer vision syndrome.
Authors: Singh VA; Department of Ophthalmology, Government Medical College and Hospital, Chandigarh, India., Ichhpujani P, Singh T, Kumar S, Kaur N
Source: Indian journal of ophthalmology [Indian J Ophthalmol] 2026 Jan 01; Vol. 74 (1), pp. 104-110. Date of Electronic Publication: 2025 Dec 29.
Publication Type: Journal Article; Observational Study
Language: English
Journal Info: Publisher: Medknow Publications Country of Publication: India NLM ID: 0405376 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1998-3689 (Electronic) Linking ISSN: 03014738 NLM ISO Abbreviation: Indian J Ophthalmol Subsets: MEDLINE
Imprint Name(s): Publication: Mumbai : Medknow Publications
Original Publication: Bombay : All-India Ophthalmological Society
MeSH Terms: Contrast Sensitivity*/physiology , Corneal Wavefront Aberration*/physiopathology , Corneal Wavefront Aberration*/diagnosis , Corneal Wavefront Aberration*/etiology , Dry Eye Syndromes*/physiopathology , Dry Eye Syndromes*/diagnosis , Refraction, Ocular*/physiology , Cornea*/physiopathology , Cornea*/pathology , Visual Acuity* , Computer Terminals*, Humans ; Male ; Prospective Studies ; Female ; Adult ; Young Adult ; Adolescent ; Case-Control Studies ; Aberrometry ; Corneal Topography ; Syndrome
Abstract: Purpose: To evaluate changes in ocular surface parameters, contrast sensitivity (CS), and higher-order aberrations (HOAs) in patients with computer vision syndrome (CVS)/digital eye strain (DES), and to assess associations among these factors.
Design: Prospective observational case-control study.
Methods: Both eyes of 55 CVS cases (CVS-Q score ≥ 6) and 55 age-matched controls (18-40 years) with best-corrected visual acuity (BCVA) of 6/6 were enrolled. Participants with ocular comorbidities were excluded. Central and peripheral CS were assessed using the Pelli-Robson (PR) chart and Spaeth-Richman contrast sensitivity test (SPARCS). Dry eye disease (DED) workup was performed. HOAs were measured using a wavefront aberrometer (iDesign® Refractive Studio, Johnson and Johnson Surgical Vision, Inc.).
Results: PR scores were identical across groups. SPARCS revealed significantly reduced total CS scores (central and peripheral) in the CVS group (W = 3641.000, P < 0.001), highlighting its sensitivity to subtle CS changes. The CVS group showed significantly higher HOA values (%), root mean square HOA error (P < 0.001), and spherical aberration (P = 0.033), along with more severe DED findings.
Conclusion: CVS/DES leads to impaired visual function due to reduced CS, increased HOAs, and dry eye. Assessment of both central and peripheral CS provides a more complete understanding of its impact on visual quality and daily functioning. Early ergonomic interventions and preventive strategies are vital for protecting ocular health in an increasingly digital world.
(Copyright © 2025 Indian Journal of Ophthalmology.)
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Contributed Indexing: Keywords: Computer vision syndrome; SPARCS; contrast sensitivity; dry eye disease; higher-order aberration
Entry Date(s): Date Created: 20251229 Date Completed: 20251229 Latest Revision: 20260521
Update Code: 20260521
PubMed Central ID: PMC12867289
DOI: 10.4103/IJO.IJO_1441_25
PMID: 41460138
Database: MEDLINE
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