Academic Journal
Προβολή σε EDS

Comparative Patterns in CKD among Native Israeli and Immigrant Ethnic Populations.

Λεπτομέρειες βιβλιογραφικής εγγραφής
Τίτλος: Comparative Patterns in CKD among Native Israeli and Immigrant Ethnic Populations.
Συγγραφείς: Einbinder Y; Department of Nephrology and Hypertension, Meir Medical Center, Kfar Saba, Israel.; Faculty of Medical and Health Sciences, Tel Aviv University, Tel Aviv, Israel., Hornik-Lurie T; Research Institute Meir Medical Center, Kfar Saba, Israel., Cohen-Hagai K; Department of Nephrology and Hypertension, Meir Medical Center, Kfar Saba, Israel.; Faculty of Medical and Health Sciences, Tel Aviv University, Tel Aviv, Israel., Benchitrit S; Department of Nephrology and Hypertension, Meir Medical Center, Kfar Saba, Israel.; Faculty of Medical and Health Sciences, Tel Aviv University, Tel Aviv, Israel., Kalantar-Zadeh K; Division of Nephrology, Hypertension and Kidney Transplantation, Harbor-UCLA Medical Center, West Carson, California.; The Lundquist Institute, Torrance, California.; Tibor Rubin Veterans Affairs Medical Center, Long Beach, California., Karpati T; Department of Digital Medical Technologies, School of Computer Science, Institute of Technology, Holon, Israel.
Πηγή: Clinical journal of the American Society of Nephrology : CJASN [Clin J Am Soc Nephrol] 2026 Jul 01; Vol. 21 (7), pp. 1269-1277. Date of Electronic Publication: 2025 Dec 01.
Τύπος έκδοσης: Journal Article; Comparative Study
Γλώσσα: English
Στοιχεία περιοδικού: Publisher: Wolters Kluwer Health Country of Publication: United States NLM ID: 101271570 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1555-905X (Electronic) Linking ISSN: 15559041 NLM ISO Abbreviation: Clin J Am Soc Nephrol Subsets: MEDLINE
Imprint Name(s): Publication: 2023- : Hagerstown, MD : Wolters Kluwer Health
Original Publication: Washington, D.C. : American Society of Nephrology, c2005-
Ιατρικοί όροι (MeSH): Arabs*/statistics & numerical data , Emigrants and Immigrants*/statistics & numerical data , Jews*/statistics & numerical data , Renal Insufficiency, Chronic*/ethnology , Renal Insufficiency, Chronic*/physiopathology , Renal Insufficiency, Chronic*/therapy , Renal Insufficiency, Chronic*/diagnosis , Ethnicity*/statistics & numerical data, Ethiopia/ethnology ; Israel/epidemiology ; Israel/ethnology ; USSR/ethnology ; Adult ; Aged ; Female ; Humans ; Male ; Middle Aged ; Disease Progression ; Glomerular Filtration Rate ; Longitudinal Studies ; Prevalence ; Retrospective Studies ; Risk Factors
Περίληψη: CKD is a prevalent condition that contributes significantly to morbidity and mortality. The prevalence and progression of CKD vary across different ethnic groups. This study aimed to evaluate the prevalence and progression of CKD among various ethnic populations in the state of Israel including native Israelis and immigrant communities. This retrospective longitudinal cohort study included immigrants from Ethiopia and the former Soviet Union as well as native-born Arab and Jewish populations in Israel. Data were obtained from the electronic medical records of Clalit Health Services, the largest health care organization in Israel, serving over 4.7 million members. CKD progression was assessed based on eGFR derived from serum creatinine measurements, identifying cases with a ≥50% decline in eGFR, initiation of renal replacement therapy, or death during the study period. The cohort included 1,612,415 Clalit Health Services members, including 40,599 Ethiopian immigrants (mean age 45.6±15.9 years), 273,330 former Soviet Union immigrants (mean age 55.9±17.4 years), 399,965 Israeli-born Arab individuals (mean age 43.7±13.8 years), and 898,521 Israeli-born Jewish individuals (mean age 43.1±14.3 years). Ethiopian immigrants had a higher baseline eGFR, lower traditional risk factors, and lowest prevalence of CKD stages 3 and 4. However, CKD progression was faster among the younger subset of this group, <50 years, with hazard ratio of 1.47 (95% confidence interval, 1.30 to 1.66) for ≥50% decline in eGFR. The native Arab population had the highest body mass index and higher prevalence of diabetes and demonstrated the highest risk of ≥50% decline in eGFR (hazard ratio,1.75; 95% confidence interval, 1.72 to 1.78), consistent across all age groups. Young Ethiopian individuals demonstrated higher risk and faster decline in eGFR independent of traditional risk factors. The native Arab population had highest risk for CKD progression across all ages. Further studies focusing on both of these ethnic populations are urgently needed.
(Copyright © 2025 by the American Society of Nephrology.)
References: Hill NR, Fatoba ST, Oke JL, et al. Global prevalence of chronic kidney disease - a systematic review and meta-analysis. PLoS One. 2016;11(7):e0158765. doi: 10.1371/journal.pone.0158765. (PMID: 10.1371/journal.pone.0158765)
Thompson S, James M, Wiebe N, et al. Cause of death in patients with reduced kidney function. J Am Soc Nephrol. 2015;26(10):2504–2511. doi: 10.1681/ASN.2014070714. (PMID: 10.1681/ASN.2014070714)
Saran R, Robinson B, Abbott KC, et al. US Renal Data System 2019 annual data report: epidemiology of kidney disease in the United States. Am J Kidney Dis. 2020;75(1 suppl 1):A6–A7. doi: 10.1053/j.ajkd.2019.09.003. (PMID: 10.1053/j.ajkd.2019.09.003)
Kalantar-Zadeh K, Jafar TH, Nitsch D, Neuen BL, Perkovic V. Chronic kidney disease. Lancet. 2021;398(10302):786–802. doi: 10.1016/S0140-6736(21)00519-5. (PMID: 10.1016/S0140-6736(21)00519-5)
Chu CD, Powe NR, McCulloch CE, et al. Trends in chronic kidney disease care in the US by race and ethnicity, 2012-2019. JAMA Netw Open. 2021;4(9):e2127014. doi: 10.1001/jamanetworkopen.2021.27014. (PMID: 10.1001/jamanetworkopen.2021.27014)
Perl J, McArthur E, Tan VS, et al. ESRD among immigrants to Ontario, Canada: a population-based study. J Am Soc Nephrol. 2018;29(7):1948–1959. doi: 10.1681/ASN.2017101055. (PMID: 10.1681/ASN.2017101055)
Sundström J, Bodegard J, Bollmann A, et al. Prevalence, outcomes, and cost of chronic kidney disease in a contemporary population of 2·4 million patients from 11 countries: the CaReMe CKD study. Lancet Reg Health Eur. 2022;20:100438. doi: 10.1016/j.lanepe.2022.100438. (PMID: 10.1016/j.lanepe.2022.100438)
Wilf-Miron R, Myers V, Saban M, et al. Inequalities in end-stage renal disease: underprivileged and ethnic minority members are at higher risk. Int J Epidemiol. 2023;52(5):1569–1578. doi: 10.1093/ije/dyad031. (PMID: 10.1093/ije/dyad031)
CBS Publication. CBS Israel CB Statistics; 2019. Accessed September 25, 2023. https://www.cbs.gov.il/he/publications/Pages/2020/%D7%90%D7%95%D7%9B%D7%9C%D7%95%D7%A1%D7%99%D7%99%D7%94-%D7%9E%D7%9E%D7%95%D7%A6%D7%90-%D7%90%D7%AA%D7%99%D7%95%D7%A4%D7%99-2018-2014.aspx.
Stanifer JW, Jing B, Tolan S, et al. The epidemiology of chronic kidney disease in Sub-Saharan Africa: a systematic review and meta-analysis. Lancet Glob Health. 2014;2(3):e174–e181. doi: 10.1016/S2214-109X(14)70002-6. (PMID: 10.1016/S2214-109X(14)70002-6)
Vart P, Powe NR, McCulloch CE, et al. National trends in the prevalence of chronic kidney disease among racial/ethnic and socioeconomic status groups, 1988-2016. JAMA Netw Open. 2020;3(7):e207932. doi: 10.1001/jamanetworkopen.2020.7932. (PMID: 10.1001/jamanetworkopen.2020.7932)
Clarfield AM, Manor O, Nun GB, et al. Health and health care in Israel: an introduction. Lancet. 2017;389(10088):2503–2513. doi: 10.1016/S0140-6736(17)30636-0. (PMID: 10.1016/S0140-6736(17)30636-0)
Levey AS, Stevens LA, Schmid CH, et al. A new equation to estimate glomerular filtration rate. Ann Intern Med. 2009;150(9):604–612. doi: 10.7326/0003-4819-150-9-200905050-00006. (PMID: 10.7326/0003-4819-150-9-200905050-00006)
Yilma D, Abdissa A, Kæstel P, et al. Serum creatinine and estimated glomerular filtration rates in HIV positive and negative adults in Ethiopia. PLoS One. 2019;14(2):e0211630. doi: 10.1371/journal.pone.0211630. (PMID: 10.1371/journal.pone.0211630)
Inker LA, Astor BC, Fox CH, et al. KDOQI US commentary on the 2012 KDIGO clinical practice guideline for the evaluation and management of CKD. Am J Kidney Dis. 2014;63(5):713–735. doi: 10.1053/j.ajkd.2014.01.416. (PMID: 10.1053/j.ajkd.2014.01.416)
Fine JP, Gray RJ. A proportional hazards model for the subdistribution of a competing risk. J Am Stat Assoc. 1999;94(446):496–509. doi: 10.1080/01621459.1999.10474144. (PMID: 10.1080/01621459.1999.10474144)
Austin PC, Steyerberg EW, Putter H. Fine-Gray subdistribution hazard models to simultaneously estimate the absolute risk of different event types: cumulative total failure probability may exceed 1. Stat Med. 2021;40(19):4200–4212. doi: 10.1002/sim.9023. (PMID: 10.1002/sim.9023)
Hamiel U, Pinhas-Hamiel O, Vivante A, et al. Impact of immigration on body mass index and blood pressure among adolescent males and females: a nationwide study. Hypertension. 2019;74(6):1316–1323. doi: 10.1161/HYPERTENSIONAHA.119.13706. (PMID: 10.1161/HYPERTENSIONAHA.119.13706)
Rosenthal T, Touyz RM, Oparil S. Migrating populations and health: risk factors for cardiovascular disease and metabolic syndrome. Curr Hypertens Rep. 2022;24(9):325–340. doi: 10.1007/s11906-022-01194-5. (PMID: 10.1007/s11906-022-01194-5)
Kruzel-Davila E, Wasser WG, Skorecki K. APOL1 nephropathy: a population genetics and evolutionary medicine detective story. Semin Nephrol. 2017;37(6):490–507. doi: 10.1016/j.semnephrol.2017.07.002. (PMID: 10.1016/j.semnephrol.2017.07.002)
Behar DM, Kedem E, Rosset S, et al. Absence of APOL1 risk variants protects against HIV-associated nephropathy in the Ethiopian population. Am J Nephrol. 2011;34(5):452–459. doi: 10.1159/000332378. (PMID: 10.1159/000332378)
Wasser WG, Tzur S, Wolday D, et al. Population genetics of chronic kidney disease: the evolving story of APOL1. J Nephrol. 2012;25(5):603–618. doi: 10.5301/jn.5000179. (PMID: 10.5301/jn.5000179)
Contributed Indexing: Keywords: CKD nondialysis; chronic kidney failure; clinical epidemiology; progression of renal failure
Entry Date(s): Date Created: 20251201 Date Completed: 20260710 Latest Revision: 20260726
Update Code: 20260726
PubMed Central ID: PMC13379119
DOI: 10.2215/CJN.0000000919
PMID: 41325014
Βάση Δεδομένων: MEDLINE
FullText Text:
  Availability: 0
Header DbId: cmedm
DbLabel: MEDLINE
An: 41325014
AccessLevel: 3
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
IllustrationInfo
Items – Name: Title
  Label: Title
  Group: Ti
  Data: Comparative Patterns in CKD among Native Israeli and Immigrant Ethnic Populations.
– Name: Author
  Label: Authors
  Group: Au
  Data: &lt;searchLink fieldCode=&quot;AU&quot; term=&quot;%22Einbinder+Y%22&quot;&gt;Einbinder Y&lt;/searchLink&gt;; Department of Nephrology and Hypertension, Meir Medical Center, Kfar Saba, Israel.; Faculty of Medical and Health Sciences, Tel Aviv University, Tel Aviv, Israel.&lt;br /&gt;&lt;searchLink fieldCode=&quot;AU&quot; term=&quot;%22Hornik-Lurie+T%22&quot;&gt;Hornik-Lurie T&lt;/searchLink&gt;; Research Institute Meir Medical Center, Kfar Saba, Israel.&lt;br /&gt;&lt;searchLink fieldCode=&quot;AU&quot; term=&quot;%22Cohen-Hagai+K%22&quot;&gt;Cohen-Hagai K&lt;/searchLink&gt;; Department of Nephrology and Hypertension, Meir Medical Center, Kfar Saba, Israel.; Faculty of Medical and Health Sciences, Tel Aviv University, Tel Aviv, Israel.&lt;br /&gt;&lt;searchLink fieldCode=&quot;AU&quot; term=&quot;%22Benchitrit+S%22&quot;&gt;Benchitrit S&lt;/searchLink&gt;; Department of Nephrology and Hypertension, Meir Medical Center, Kfar Saba, Israel.; Faculty of Medical and Health Sciences, Tel Aviv University, Tel Aviv, Israel.&lt;br /&gt;&lt;searchLink fieldCode=&quot;AU&quot; term=&quot;%22Kalantar-Zadeh+K%22&quot;&gt;Kalantar-Zadeh K&lt;/searchLink&gt;; Division of Nephrology, Hypertension and Kidney Transplantation, Harbor-UCLA Medical Center, West Carson, California.; The Lundquist Institute, Torrance, California.; Tibor Rubin Veterans Affairs Medical Center, Long Beach, California.&lt;br /&gt;&lt;searchLink fieldCode=&quot;AU&quot; term=&quot;%22Karpati+T%22&quot;&gt;Karpati T&lt;/searchLink&gt;; Department of Digital Medical Technologies, School of Computer Science, Institute of Technology, Holon, Israel.
– Name: TitleSource
  Label: Source
  Group: Src
  Data: &lt;searchLink fieldCode=&quot;JN&quot; term=&quot;%22101271570%22&quot;&gt;Clinical journal of the American Society of Nephrology : CJASN&lt;/searchLink&gt; [Clin J Am Soc Nephrol] 2026 Jul 01; Vol. 21 (7), pp. 1269-1277. &lt;i&gt;Date of Electronic Publication: &lt;/i&gt;2025 Dec 01.
– Name: TypePub
  Label: Publication Type
  Group: TypPub
  Data: Journal Article; Comparative Study
– Name: Language
  Label: Language
  Group: Lang
  Data: English
– Name: TitleSource
  Label: Journal Info
  Group: Src
  Data: &lt;i&gt;Publisher: &lt;/i&gt;&lt;searchLink fieldCode=&quot;PB&quot; term=&quot;%22Wolters+Kluwer+Health%22&quot;&gt;Wolters Kluwer Health &lt;/searchLink&gt;&lt;i&gt;Country of Publication: &lt;/i&gt;United States &lt;i&gt;NLM ID: &lt;/i&gt;101271570 &lt;i&gt;Publication Model: &lt;/i&gt;Print-Electronic &lt;i&gt;Cited Medium: &lt;/i&gt;Internet &lt;i&gt;ISSN: &lt;/i&gt;1555-905X (Electronic) &lt;i&gt;Linking ISSN: &lt;/i&gt;&lt;searchLink fieldCode=&quot;IS&quot; term=&quot;%2215559041%22&quot;&gt;15559041 &lt;/searchLink&gt;&lt;i&gt;NLM ISO Abbreviation: &lt;/i&gt;Clin J Am Soc Nephrol &lt;i&gt;Subsets: &lt;/i&gt;MEDLINE
– Name: PublisherInfo
  Label: Imprint Name(s)
  Group: PubInfo
  Data: &lt;i&gt;Publication&lt;/i&gt;: 2023- : Hagerstown, MD : Wolters Kluwer Health&lt;br /&gt;&lt;i&gt;Original Publication&lt;/i&gt;: Washington, D.C. : American Society of Nephrology, c2005-
– Name: SubjectMESH
  Label: MeSH Terms
  Group: Su
  Data: &lt;searchLink fieldCode=&quot;MM&quot; term=&quot;%22Arabs%22&quot;&gt;Arabs*&lt;/searchLink&gt;/&lt;searchLink fieldCode=&quot;MM&quot; term=&quot;%22Arabs+statistics+%26+numerical+data%22&quot;&gt;statistics &amp; numerical data&lt;/searchLink&gt; &lt;br /&gt;&lt;searchLink fieldCode=&quot;MM&quot; term=&quot;%22Emigrants+and+Immigrants%22&quot;&gt;Emigrants and Immigrants*&lt;/searchLink&gt;/&lt;searchLink fieldCode=&quot;MM&quot; term=&quot;%22Emigrants+and+Immigrants+statistics+%26+numerical+data%22&quot;&gt;statistics &amp; numerical data&lt;/searchLink&gt; &lt;br /&gt;&lt;searchLink fieldCode=&quot;MM&quot; term=&quot;%22Jews%22&quot;&gt;Jews*&lt;/searchLink&gt;/&lt;searchLink fieldCode=&quot;MM&quot; term=&quot;%22Jews+statistics+%26+numerical+data%22&quot;&gt;statistics &amp; numerical data&lt;/searchLink&gt; &lt;br /&gt;&lt;searchLink fieldCode=&quot;MM&quot; term=&quot;%22Renal+Insufficiency%2C+Chronic%22&quot;&gt;Renal Insufficiency, Chronic*&lt;/searchLink&gt;/&lt;searchLink fieldCode=&quot;MM&quot; term=&quot;%22Renal+Insufficiency%2C+Chronic+ethnology%22&quot;&gt;ethnology&lt;/searchLink&gt; &lt;br /&gt;&lt;searchLink fieldCode=&quot;MM&quot; term=&quot;%22Renal+Insufficiency%2C+Chronic%22&quot;&gt;Renal Insufficiency, Chronic*&lt;/searchLink&gt;/&lt;searchLink fieldCode=&quot;MM&quot; term=&quot;%22Renal+Insufficiency%2C+Chronic+physiopathology%22&quot;&gt;physiopathology&lt;/searchLink&gt; &lt;br /&gt;&lt;searchLink fieldCode=&quot;MM&quot; term=&quot;%22Renal+Insufficiency%2C+Chronic%22&quot;&gt;Renal Insufficiency, Chronic*&lt;/searchLink&gt;/&lt;searchLink fieldCode=&quot;MM&quot; term=&quot;%22Renal+Insufficiency%2C+Chronic+therapy%22&quot;&gt;therapy&lt;/searchLink&gt; &lt;br /&gt;&lt;searchLink fieldCode=&quot;MM&quot; term=&quot;%22Renal+Insufficiency%2C+Chronic%22&quot;&gt;Renal Insufficiency, Chronic*&lt;/searchLink&gt;/&lt;searchLink fieldCode=&quot;MM&quot; term=&quot;%22Renal+Insufficiency%2C+Chronic+diagnosis%22&quot;&gt;diagnosis&lt;/searchLink&gt; &lt;br /&gt;&lt;searchLink fieldCode=&quot;MM&quot; term=&quot;%22Ethnicity%22&quot;&gt;Ethnicity*&lt;/searchLink&gt;/&lt;searchLink fieldCode=&quot;MM&quot; term=&quot;%22Ethnicity+statistics+%26+numerical+data%22&quot;&gt;statistics &amp; numerical data&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;MH&quot; term=&quot;%22Ethiopia%22&quot;&gt;Ethiopia&lt;/searchLink&gt;/&lt;searchLink fieldCode=&quot;MH&quot; term=&quot;%22Ethiopia+ethnology%22&quot;&gt;ethnology&lt;/searchLink&gt; ; &lt;searchLink fieldCode=&quot;MH&quot; term=&quot;%22Israel%22&quot;&gt;Israel&lt;/searchLink&gt;/&lt;searchLink fieldCode=&quot;MH&quot; term=&quot;%22Israel+epidemiology%22&quot;&gt;epidemiology&lt;/searchLink&gt; ; &lt;searchLink fieldCode=&quot;MH&quot; term=&quot;%22Israel%22&quot;&gt;Israel&lt;/searchLink&gt;/&lt;searchLink fieldCode=&quot;MH&quot; term=&quot;%22Israel+ethnology%22&quot;&gt;ethnology&lt;/searchLink&gt; ; &lt;searchLink fieldCode=&quot;MH&quot; term=&quot;%22USSR%22&quot;&gt;USSR&lt;/searchLink&gt;/&lt;searchLink fieldCode=&quot;MH&quot; term=&quot;%22USSR+ethnology%22&quot;&gt;ethnology&lt;/searchLink&gt; ; &lt;searchLink fieldCode=&quot;MH&quot; term=&quot;%22Adult%22&quot;&gt;Adult&lt;/searchLink&gt; ; &lt;searchLink fieldCode=&quot;MH&quot; term=&quot;%22Aged%22&quot;&gt;Aged&lt;/searchLink&gt; ; &lt;searchLink fieldCode=&quot;MH&quot; term=&quot;%22Female%22&quot;&gt;Female&lt;/searchLink&gt; ; &lt;searchLink fieldCode=&quot;MH&quot; term=&quot;%22Humans%22&quot;&gt;Humans&lt;/searchLink&gt; ; &lt;searchLink fieldCode=&quot;MH&quot; term=&quot;%22Male%22&quot;&gt;Male&lt;/searchLink&gt; ; &lt;searchLink fieldCode=&quot;MH&quot; term=&quot;%22Middle+Aged%22&quot;&gt;Middle Aged&lt;/searchLink&gt; ; &lt;searchLink fieldCode=&quot;MH&quot; term=&quot;%22Disease+Progression%22&quot;&gt;Disease Progression&lt;/searchLink&gt; ; &lt;searchLink fieldCode=&quot;MH&quot; term=&quot;%22Glomerular+Filtration+Rate%22&quot;&gt;Glomerular Filtration Rate&lt;/searchLink&gt; ; &lt;searchLink fieldCode=&quot;MH&quot; term=&quot;%22Longitudinal+Studies%22&quot;&gt;Longitudinal Studies&lt;/searchLink&gt; ; &lt;searchLink fieldCode=&quot;MH&quot; term=&quot;%22Prevalence%22&quot;&gt;Prevalence&lt;/searchLink&gt; ; &lt;searchLink fieldCode=&quot;MH&quot; term=&quot;%22Retrospective+Studies%22&quot;&gt;Retrospective Studies&lt;/searchLink&gt; ; &lt;searchLink fieldCode=&quot;MH&quot; term=&quot;%22Risk+Factors%22&quot;&gt;Risk Factors&lt;/searchLink&gt;
– Name: Abstract
  Label: Abstract
  Group: Ab
  Data: CKD is a prevalent condition that contributes significantly to morbidity and mortality. The prevalence and progression of CKD vary across different ethnic groups. This study aimed to evaluate the prevalence and progression of CKD among various ethnic populations in the state of Israel including native Israelis and immigrant communities. This retrospective longitudinal cohort study included immigrants from Ethiopia and the former Soviet Union as well as native-born Arab and Jewish populations in Israel. Data were obtained from the electronic medical records of Clalit Health Services, the largest health care organization in Israel, serving over 4.7 million members. CKD progression was assessed based on eGFR derived from serum creatinine measurements, identifying cases with a ≥50% decline in eGFR, initiation of renal replacement therapy, or death during the study period. The cohort included 1,612,415 Clalit Health Services members, including 40,599 Ethiopian immigrants (mean age 45.6&#177;15.9 years), 273,330 former Soviet Union immigrants (mean age 55.9&#177;17.4 years), 399,965 Israeli-born Arab individuals (mean age 43.7&#177;13.8 years), and 898,521 Israeli-born Jewish individuals (mean age 43.1&#177;14.3 years). Ethiopian immigrants had a higher baseline eGFR, lower traditional risk factors, and lowest prevalence of CKD stages 3 and 4. However, CKD progression was faster among the younger subset of this group, &amp;lt;50 years, with hazard ratio of 1.47 (95% confidence interval, 1.30 to 1.66) for ≥50% decline in eGFR. The native Arab population had the highest body mass index and higher prevalence of diabetes and demonstrated the highest risk of ≥50% decline in eGFR (hazard ratio,1.75; 95% confidence interval, 1.72 to 1.78), consistent across all age groups. Young Ethiopian individuals demonstrated higher risk and faster decline in eGFR independent of traditional risk factors. The native Arab population had highest risk for CKD progression across all ages. Further studies focusing on both of these ethnic populations are urgently needed.&lt;br /&gt; (Copyright &#169; 2025 by the American Society of Nephrology.)
– Name: Ref
  Label: References
  Group: RefInfo
  Data: Hill NR, Fatoba ST, Oke JL, et al. Global prevalence of chronic kidney disease - a systematic review and meta-analysis. PLoS One. 2016;11(7):e0158765. doi: 10.1371/journal.pone.0158765. (PMID: &lt;searchLink fieldCode=&quot;PM&quot; term=&quot;%2210%2E1371%2Fjournal%2Epone%2E0158765%22&quot;&gt;10.1371/journal.pone.0158765)&lt;/searchLink&gt;&lt;br /&gt;Thompson S, James M, Wiebe N, et al. Cause of death in patients with reduced kidney function. J Am Soc Nephrol. 2015;26(10):2504–2511. doi: 10.1681/ASN.2014070714. (PMID: &lt;searchLink fieldCode=&quot;PM&quot; term=&quot;%2210%2E1681%2FASN%2E2014070714%22&quot;&gt;10.1681/ASN.2014070714)&lt;/searchLink&gt;&lt;br /&gt;Saran R, Robinson B, Abbott KC, et al. US Renal Data System 2019 annual data report: epidemiology of kidney disease in the United States. Am J Kidney Dis. 2020;75(1 suppl 1):A6–A7. doi: 10.1053/j.ajkd.2019.09.003. (PMID: &lt;searchLink fieldCode=&quot;PM&quot; term=&quot;%2210%2E1053%2Fj%2Eajkd%2E2019%2E09%2E003%22&quot;&gt;10.1053/j.ajkd.2019.09.003)&lt;/searchLink&gt;&lt;br /&gt;Kalantar-Zadeh K, Jafar TH, Nitsch D, Neuen BL, Perkovic V. Chronic kidney disease. Lancet. 2021;398(10302):786–802. doi: 10.1016/S0140-6736(21)00519-5. (PMID: &lt;searchLink fieldCode=&quot;PM&quot; term=&quot;%2210%2E1016%2FS0140-6736%2821%2900519-5%22&quot;&gt;10.1016/S0140-6736(21)00519-5)&lt;/searchLink&gt;&lt;br /&gt;Chu CD, Powe NR, McCulloch CE, et al. Trends in chronic kidney disease care in the US by race and ethnicity, 2012-2019. JAMA Netw Open. 2021;4(9):e2127014. doi: 10.1001/jamanetworkopen.2021.27014. (PMID: &lt;searchLink fieldCode=&quot;PM&quot; term=&quot;%2210%2E1001%2Fjamanetworkopen%2E2021%2E27014%22&quot;&gt;10.1001/jamanetworkopen.2021.27014)&lt;/searchLink&gt;&lt;br /&gt;Perl J, McArthur E, Tan VS, et al. ESRD among immigrants to Ontario, Canada: a population-based study. J Am Soc Nephrol. 2018;29(7):1948–1959. doi: 10.1681/ASN.2017101055. (PMID: &lt;searchLink fieldCode=&quot;PM&quot; term=&quot;%2210%2E1681%2FASN%2E2017101055%22&quot;&gt;10.1681/ASN.2017101055)&lt;/searchLink&gt;&lt;br /&gt;Sundstr&#246;m J, Bodegard J, Bollmann A, et al. Prevalence, outcomes, and cost of chronic kidney disease in a contemporary population of 2&#183;4 million patients from 11 countries: the CaReMe CKD study. Lancet Reg Health Eur. 2022;20:100438. doi: 10.1016/j.lanepe.2022.100438. (PMID: &lt;searchLink fieldCode=&quot;PM&quot; term=&quot;%2210%2E1016%2Fj%2Elanepe%2E2022%2E100438%22&quot;&gt;10.1016/j.lanepe.2022.100438)&lt;/searchLink&gt;&lt;br /&gt;Wilf-Miron R, Myers V, Saban M, et al. Inequalities in end-stage renal disease: underprivileged and ethnic minority members are at higher risk. Int J Epidemiol. 2023;52(5):1569–1578. doi: 10.1093/ije/dyad031. (PMID: &lt;searchLink fieldCode=&quot;PM&quot; term=&quot;%2210%2E1093%2Fije%2Fdyad031%22&quot;&gt;10.1093/ije/dyad031)&lt;/searchLink&gt;&lt;br /&gt;CBS Publication. CBS Israel CB Statistics; 2019. Accessed September 25, 2023. https://www.cbs.gov.il/he/publications/Pages/2020/%D7%90%D7%95%D7%9B%D7%9C%D7%95%D7%A1%D7%99%D7%99%D7%94-%D7%9E%D7%9E%D7%95%D7%A6%D7%90-%D7%90%D7%AA%D7%99%D7%95%D7%A4%D7%99-2018-2014.aspx.&lt;br /&gt;Stanifer JW, Jing B, Tolan S, et al. The epidemiology of chronic kidney disease in Sub-Saharan Africa: a systematic review and meta-analysis. Lancet Glob Health. 2014;2(3):e174–e181. doi: 10.1016/S2214-109X(14)70002-6. (PMID: &lt;searchLink fieldCode=&quot;PM&quot; term=&quot;%2210%2E1016%2FS2214-109X%2814%2970002-6%22&quot;&gt;10.1016/S2214-109X(14)70002-6)&lt;/searchLink&gt;&lt;br /&gt;Vart P, Powe NR, McCulloch CE, et al. National trends in the prevalence of chronic kidney disease among racial/ethnic and socioeconomic status groups, 1988-2016. JAMA Netw Open. 2020;3(7):e207932. doi: 10.1001/jamanetworkopen.2020.7932. (PMID: &lt;searchLink fieldCode=&quot;PM&quot; term=&quot;%2210%2E1001%2Fjamanetworkopen%2E2020%2E7932%22&quot;&gt;10.1001/jamanetworkopen.2020.7932)&lt;/searchLink&gt;&lt;br /&gt;Clarfield AM, Manor O, Nun GB, et al. Health and health care in Israel: an introduction. Lancet. 2017;389(10088):2503–2513. doi: 10.1016/S0140-6736(17)30636-0. (PMID: &lt;searchLink fieldCode=&quot;PM&quot; term=&quot;%2210%2E1016%2FS0140-6736%2817%2930636-0%22&quot;&gt;10.1016/S0140-6736(17)30636-0)&lt;/searchLink&gt;&lt;br /&gt;Levey AS, Stevens LA, Schmid CH, et al. A new equation to estimate glomerular filtration rate. Ann Intern Med. 2009;150(9):604–612. doi: 10.7326/0003-4819-150-9-200905050-00006. (PMID: &lt;searchLink fieldCode=&quot;PM&quot; term=&quot;%2210%2E7326%2F0003-4819-150-9-200905050-00006%22&quot;&gt;10.7326/0003-4819-150-9-200905050-00006)&lt;/searchLink&gt;&lt;br /&gt;Yilma D, Abdissa A, K&#230;stel P, et al. Serum creatinine and estimated glomerular filtration rates in HIV positive and negative adults in Ethiopia. PLoS One. 2019;14(2):e0211630. doi: 10.1371/journal.pone.0211630. (PMID: &lt;searchLink fieldCode=&quot;PM&quot; term=&quot;%2210%2E1371%2Fjournal%2Epone%2E0211630%22&quot;&gt;10.1371/journal.pone.0211630)&lt;/searchLink&gt;&lt;br /&gt;Inker LA, Astor BC, Fox CH, et al. KDOQI US commentary on the 2012 KDIGO clinical practice guideline for the evaluation and management of CKD. Am J Kidney Dis. 2014;63(5):713–735. doi: 10.1053/j.ajkd.2014.01.416. (PMID: &lt;searchLink fieldCode=&quot;PM&quot; term=&quot;%2210%2E1053%2Fj%2Eajkd%2E2014%2E01%2E416%22&quot;&gt;10.1053/j.ajkd.2014.01.416)&lt;/searchLink&gt;&lt;br /&gt;Fine JP, Gray RJ. A proportional hazards model for the subdistribution of a competing risk. J Am Stat Assoc. 1999;94(446):496–509. doi: 10.1080/01621459.1999.10474144. (PMID: &lt;searchLink fieldCode=&quot;PM&quot; term=&quot;%2210%2E1080%2F01621459%2E1999%2E10474144%22&quot;&gt;10.1080/01621459.1999.10474144)&lt;/searchLink&gt;&lt;br /&gt;Austin PC, Steyerberg EW, Putter H. Fine-Gray subdistribution hazard models to simultaneously estimate the absolute risk of different event types: cumulative total failure probability may exceed 1. Stat Med. 2021;40(19):4200–4212. doi: 10.1002/sim.9023. (PMID: &lt;searchLink fieldCode=&quot;PM&quot; term=&quot;%2210%2E1002%2Fsim%2E9023%22&quot;&gt;10.1002/sim.9023)&lt;/searchLink&gt;&lt;br /&gt;Hamiel U, Pinhas-Hamiel O, Vivante A, et al. Impact of immigration on body mass index and blood pressure among adolescent males and females: a nationwide study. Hypertension. 2019;74(6):1316–1323. doi: 10.1161/HYPERTENSIONAHA.119.13706. (PMID: &lt;searchLink fieldCode=&quot;PM&quot; term=&quot;%2210%2E1161%2FHYPERTENSIONAHA%2E119%2E13706%22&quot;&gt;10.1161/HYPERTENSIONAHA.119.13706)&lt;/searchLink&gt;&lt;br /&gt;Rosenthal T, Touyz RM, Oparil S. Migrating populations and health: risk factors for cardiovascular disease and metabolic syndrome. Curr Hypertens Rep. 2022;24(9):325–340. doi: 10.1007/s11906-022-01194-5. (PMID: &lt;searchLink fieldCode=&quot;PM&quot; term=&quot;%2210%2E1007%2Fs11906-022-01194-5%22&quot;&gt;10.1007/s11906-022-01194-5)&lt;/searchLink&gt;&lt;br /&gt;Kruzel-Davila E, Wasser WG, Skorecki K. APOL1 nephropathy: a population genetics and evolutionary medicine detective story. Semin Nephrol. 2017;37(6):490–507. doi: 10.1016/j.semnephrol.2017.07.002. (PMID: &lt;searchLink fieldCode=&quot;PM&quot; term=&quot;%2210%2E1016%2Fj%2Esemnephrol%2E2017%2E07%2E002%22&quot;&gt;10.1016/j.semnephrol.2017.07.002)&lt;/searchLink&gt;&lt;br /&gt;Behar DM, Kedem E, Rosset S, et al. Absence of APOL1 risk variants protects against HIV-associated nephropathy in the Ethiopian population. Am J Nephrol. 2011;34(5):452–459. doi: 10.1159/000332378. (PMID: &lt;searchLink fieldCode=&quot;PM&quot; term=&quot;%2210%2E1159%2F000332378%22&quot;&gt;10.1159/000332378)&lt;/searchLink&gt;&lt;br /&gt;Wasser WG, Tzur S, Wolday D, et al. Population genetics of chronic kidney disease: the evolving story of APOL1. J Nephrol. 2012;25(5):603–618. doi: 10.5301/jn.5000179. (PMID: &lt;searchLink fieldCode=&quot;PM&quot; term=&quot;%2210%2E5301%2Fjn%2E5000179%22&quot;&gt;10.5301/jn.5000179)&lt;/searchLink&gt;
– Name: SubjectMinor
  Label: Contributed Indexing
  Group:
  Data: &lt;i&gt;Keywords: &lt;/i&gt;CKD nondialysis; chronic kidney failure; clinical epidemiology; progression of renal failure
– Name: DateEntry
  Label: Entry Date(s)
  Group: Date
  Data: &lt;i&gt;Date Created: &lt;/i&gt;20251201 &lt;i&gt;Date Completed: &lt;/i&gt;20260710 &lt;i&gt;Latest Revision: &lt;/i&gt;20260726
– Name: DateUpdate
  Label: Update Code
  Group: Date
  Data: 20260726
– Name: PubmedCentralID
  Label: PubMed Central ID
  Group: ID
  Data: PMC13379119
– Name: DOI
  Label: DOI
  Group: ID
  Data: 10.2215/CJN.0000000919
– Name: AN
  Label: PMID
  Group: ID
  Data: 41325014
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=cmedm&AN=41325014
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.2215/CJN.0000000919
    Languages:
      – Code: eng
        Text: English
    PhysicalDescription:
      Pagination:
        StartPage: 1269
    Subjects:
      – SubjectFull: Ethiopia ethnology
        Type: general
      – SubjectFull: Israel epidemiology
        Type: general
      – SubjectFull: Israel ethnology
        Type: general
      – SubjectFull: USSR ethnology
        Type: general
      – SubjectFull: Adult
        Type: general
      – SubjectFull: Aged
        Type: general
      – SubjectFull: Female
        Type: general
      – SubjectFull: Humans
        Type: general
      – SubjectFull: Male
        Type: general
      – SubjectFull: Middle Aged
        Type: general
      – SubjectFull: Disease Progression
        Type: general
      – SubjectFull: Glomerular Filtration Rate
        Type: general
      – SubjectFull: Longitudinal Studies
        Type: general
      – SubjectFull: Prevalence
        Type: general
      – SubjectFull: Retrospective Studies
        Type: general
      – SubjectFull: Risk Factors
        Type: general
      – SubjectFull: Arabs statistics & numerical data
        Type: general
      – SubjectFull: Emigrants and Immigrants statistics & numerical data
        Type: general
      – SubjectFull: Jews statistics & numerical data
        Type: general
      – SubjectFull: Renal Insufficiency, Chronic ethnology
        Type: general
      – SubjectFull: Renal Insufficiency, Chronic physiopathology
        Type: general
      – SubjectFull: Renal Insufficiency, Chronic therapy
        Type: general
      – SubjectFull: Renal Insufficiency, Chronic diagnosis
        Type: general
      – SubjectFull: Ethnicity statistics & numerical data
        Type: general
    Titles:
      – TitleFull: Comparative Patterns in CKD among Native Israeli and Immigrant Ethnic Populations.
        Type: main
  BibRelationships:
    HasContributorRelationships:
      – PersonEntity:
          Name:
            NameFull: Einbinder Y
      – PersonEntity:
          Name:
            NameFull: Hornik-Lurie T
      – PersonEntity:
          Name:
            NameFull: Cohen-Hagai K
      – PersonEntity:
          Name:
            NameFull: Benchitrit S
      – PersonEntity:
          Name:
            NameFull: Kalantar-Zadeh K
      – PersonEntity:
          Name:
            NameFull: Karpati T
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 01
              M: 07
              Text: 2026 Jul 01
              Type: published
              Y: 2026
          Identifiers:
            – Type: issn-electronic
              Value: 1555-905X
          Numbering:
            – Type: volume
              Value: 21
            – Type: issue
              Value: 7
          Titles:
            – TitleFull: Clinical journal of the American Society of Nephrology : CJASN
              Type: main
ResultId 1