Academic Journal
Spreading depolarization and its influence on epileptiform activity.
| Τίτλος: | Spreading depolarization and its influence on epileptiform activity. |
|---|---|
| Συγγραφείς: | Lévesque M; Department of Neurology & Neurosurgery, Montreal Neurological Institute-Hospital, McGill University, Quebec, Canada., Köhling R; Oscar Langendorff Institute of Physiology, University of Rostock, Rostock, Germany., Avoli M; Department of Neurology & Neurosurgery, Montreal Neurological Institute-Hospital, McGill University, Quebec, Canada.; Department of Physiology, McGill University, Quebec, Canada. |
| Πηγή: | Epilepsia [Epilepsia] 2026 Mar; Vol. 67 (3), pp. 1078-1089. Date of Electronic Publication: 2025 Nov 08. |
| Τύπος έκδοσης: | Journal Article; Review |
| Γλώσσα: | English |
| Στοιχεία περιοδικού: | Publisher: Blackwell Science Country of Publication: United States NLM ID: 2983306R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1528-1167 (Electronic) Linking ISSN: 00139580 NLM ISO Abbreviation: Epilepsia Subsets: MEDLINE |
| Imprint Name(s): | Publication: Malden, MA : Blackwell Science Original Publication: Copenhagen : Munskgaard |
| Ιατρικοί όροι (MeSH): | Epilepsy*/physiopathology , Cortical Spreading Depression*/physiology , Cortical Spreading Depression*/drug effects, Neurons/physiology ; Humans ; Animals |
| Περίληψη: | Spreading depolarization (SD) is a transient disruption of electrographic activity that slowly propagates through the gray matter by chemical contiguity, and it is characterized by a large depolarization of neurons and glial cells. SD, which is associated with massive changes in ion homeostasis, including extreme increases in [K+] (© 2025 The Author(s). Epilepsia published by Wiley Periodicals LLC on behalf of International League Against Epilepsy.) |
| References: | Neuroscience. 1978;3(11):1045-59. (PMID: 745780) Nature. 1961 Sep 2;191:1010-1. (PMID: 13718947) J Headache Pain. 2019 May 2;20(1):45. (PMID: 31046659) Stroke. 2005 Jun;36(6):1270-7. (PMID: 15879337) J Neurophysiol. 1956 Mar;19(2):154-71. (PMID: 13295838) Front Cell Neurosci. 2022 Feb 10;16:837650. (PMID: 35237133) J Physiol. 2012 Nov 15;590(22):5877-93. (PMID: 22907056) Physiol Rev. 2001 Jul;81(3):1065-96. (PMID: 11427692) J Comput Neurosci. 2012 Oct;33(2):207-25. (PMID: 22310969) Nat Med. 2011 Apr;17(4):439-47. (PMID: 21475241) Brain Res. 1977 Mar 4;123(1):113-24. (PMID: 843909) Brain Res. 1982 Jun 10;241(2):329-33. (PMID: 7104715) Neuron. 2009 Mar 26;61(6):820-38. (PMID: 19323993) Nat Rev Neurol. 2013 Nov;9(11):637-44. (PMID: 24042483) Brain Res. 1996 Oct 7;735(2):188-96. (PMID: 8911657) J Cereb Blood Flow Metab. 1992 Mar;12(2):223-9. (PMID: 1312539) Cereb Cortex. 2015 Nov;25(11):4469-76. (PMID: 25840424) Exp Neurol. 2014 Mar;253:1-15. (PMID: 24368193) J Neurophysiol. 1999 Nov;82(5):2590-601. (PMID: 10561429) Neuroscience. 1993 Jul;55(1):57-68. (PMID: 8102481) J Neurophysiol. 1990 Feb;63(2):225-39. (PMID: 2313342) Nat Commun. 2021 Apr 13;12(1):2206. (PMID: 33850125) J Cereb Blood Flow Metab. 2011 Jan;31(1):17-35. (PMID: 21045864) J Neurophysiol. 1987 Mar;57(3):869-88. (PMID: 3031235) Brain Res. 2003 Jun 13;975(1-2):129-34. (PMID: 12763600) Am J Hum Genet. 2001 Jun;68(6):1327-32. (PMID: 11359211) Brain. 2019 Feb 1;142(2):412-425. (PMID: 30649209) J Neurochem. 1959 Feb;3(4):300-15. (PMID: 13642064) Brain. 2012 Jan;135(Pt 1):259-75. (PMID: 22120143) Neurobiol Dis. 2025 Jul;211:106937. (PMID: 40348201) J Neurophysiol. 1990 Dec;64(6):1747-57. (PMID: 2074462) J Cereb Blood Flow Metab. 2013 Oct;33(10):1582-94. (PMID: 23820646) Brain Res. 1988 Aug 9;457(2):226-40. (PMID: 2851364) J Neurophysiol. 2000 Jun;83(6):3519-24. (PMID: 10848567) J Neurosci. 1994 Nov;14(11 Pt 2):7087-98. (PMID: 7965100) J Neurosci. 1996 Jul 1;16(13):4113-28. (PMID: 8753873) Exp Neurol. 2015 May;267:243-53. (PMID: 25819105) J Neurophysiol. 1947 Nov;10(6):409-14. (PMID: 20268874) Sci Transl Med. 2025 Sep 17;17(816):eadv3260. (PMID: 40961224) Cereb Cortex. 2019 Mar 1;29(3):1150-1161. (PMID: 29425263) Brain Res Dev Brain Res. 1989 Apr 1;46(2):243-52. (PMID: 2720957) J Neurophysiol. 1988 Feb;59(2):450-67. (PMID: 3351570) Naunyn Schmiedebergs Arch Pharmacol. 1998 Mar;357(3):225-31. (PMID: 9550292) Brain Res. 1977 Jan 21;120(2):231-49. (PMID: 832122) Exp Brain Res. 1977 Mar 30;27(3-4):237-43. (PMID: 880984) Prog Neurobiol. 2018 Mar;162:1-16. (PMID: 29197650) J Neurophysiol. 2006 Jun;95(6):3948-54. (PMID: 16554499) Electroencephalogr Clin Neurophysiol. 1987 Apr;66(4):440-7. (PMID: 2435524) Neurobiol Dis. 2023 May;180:106097. (PMID: 36967064) Front Neurol. 2018 Feb 01;9:19. (PMID: 29449828) Sci Rep. 2018 Nov 16;8(1):16959. (PMID: 30446731) Epilepsia. 2019 Dec;60(12):2386-2397. (PMID: 31755112) Neuroscience. 2020 Aug 10;441:176-183. (PMID: 32450296) J Neurophysiol. 1995 Aug;74(2):565-73. (PMID: 7472364) Exp Neurol. 1976 Oct;53(1):12-20. (PMID: 964333) Nat Genet. 2000 Apr;24(4):343-5. (PMID: 10742094) Brain Res. 1993 Apr 9;608(1):107-14. (PMID: 8495335) Acta Physiol Scand. 1980 Apr;108(4):355-65. (PMID: 7415848) Neurobiol Dis. 2020 Nov;145:105071. (PMID: 32890774) Stroke. 2011 Oct;42(10):2917-22. (PMID: 21836085) Brain Res. 1972 Apr 14;39(1):255-9. (PMID: 5025649) J Neurosci. 2002 Dec 1;22(23):10106-15. (PMID: 12451111) J Neurophysiol. 1995 Feb;73(2):468-84. (PMID: 7760112) Acta Physiol Scand. 1981 Dec;113(4):437-45. (PMID: 7348028) J Neurophysiol. 1985 Apr;53(4):1098-108. (PMID: 3998794) J Neurophysiol. 1983 Mar;49(3):831-50. (PMID: 6834101) Sci Transl Med. 2015 Apr 8;7(282):282ra46. (PMID: 25855492) Nature. 1988 Nov 24;336(6197):379-81. (PMID: 3194020) J Physiol. 1996 Jun 15;493 ( Pt 3):707-17. (PMID: 8799893) |
| Grant Information: | Savoy Foundation; MOP130328 Canada CAPMC CIHR; PJT153310 Canada CAPMC CIHR; PJT166178 Canada CAPMC CIHR |
| Contributed Indexing: | Keywords: ictogenesis; seizures; spreading depolarization; sudden unexpected death in epilepsy |
| Entry Date(s): | Date Created: 20251108 Date Completed: 20260323 Latest Revision: 20260813 |
| Update Code: | 20260813 |
| PubMed Central ID: | PMC13007837 |
| DOI: | 10.1111/epi.70010 |
| PMID: | 41204888 |
| Βάση Δεδομένων: | MEDLINE |
καταχωρήστε σχόλιο πρώτοι!