Academic Journal
Spin and Gradient Multiple Overlapping-Echo Detachment Imaging (SAGE-MOLED): Highly Efficient T2, ... , and M0 Mapping for Simultaneous Perfusion and Permeability Measurements.
| Τίτλος: | Spin and Gradient Multiple Overlapping-Echo Detachment Imaging (SAGE-MOLED): Highly Efficient T |
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| Συγγραφείς: | Yang Q; Department of Electronic Science, Xiamen University, Xiamen, China.; Department of Radiological Sciences, University of California Irvine, Irvine, California, USA., Bao J; Department of Magnetic Resonance Imaging, The First Affiliated Hospital of Zhengzhou University, Zhengzhou University, Zhengzhou, China., Wang L; Department of Electronic Science, Xiamen University, Xiamen, China., Ge N; Department of Electronic Science, Xiamen University, Xiamen, China., Ma X; Department of Magnetic Resonance Imaging, The First Affiliated Hospital of Zhengzhou University, Zhengzhou University, Zhengzhou, China., Cai S; Department of Electronic Science, Xiamen University, Xiamen, China., Chen Z; Department of Electronic Science, Xiamen University, Xiamen, China., Zhang Y; Department of Magnetic Resonance Imaging, The First Affiliated Hospital of Zhengzhou University, Zhengzhou University, Zhengzhou, China., Gholipour A; Department of Radiological Sciences, University of California Irvine, Irvine, California, USA., Cai C; Department of Electronic Science, Xiamen University, Xiamen, China. |
| Πηγή: | Magnetic resonance in medicine [Magn Reson Med] 2026 Apr; Vol. 95 (4), pp. 1959-1971. Date of Electronic Publication: 2025 Nov 02. |
| Τύπος έκδοσης: | Journal Article |
| Γλώσσα: | English |
| Στοιχεία περιοδικού: | Publisher: Wiley Country of Publication: United States NLM ID: 8505245 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1522-2594 (Electronic) Linking ISSN: 07403194 NLM ISO Abbreviation: Magn Reson Med Subsets: MEDLINE |
| Imprint Name(s): | Publication: 1999- : New York, NY : Wiley Original Publication: San Diego : Academic Press |
| Ιατρικοί όροι (MeSH): | Image Processing, Computer-Assisted*/methods , Brain*/diagnostic imaging , Echo-Planar Imaging*/methods , Magnetic Resonance Imaging*, Humans ; Algorithms ; Phantoms, Imaging ; Signal-To-Noise Ratio ; Adult ; Male ; Female ; Permeability ; Computer Simulation ; Cerebrovascular Circulation |
| Περίληψη: | Purpose: Combined spin- and gradient-echo EPI (SAGE-EPI) offers advantages in tissue quantification and dynamic imaging but suffers from low spatial resolution and geometric distortions. This study aims to develop a multiple overlapping-echo detachment-based SAGE acquisition (SAGE-MOLED) to enable efficient, distortion-corrected T Methods: SAGE-MOLED was designed as an optimized MOLED variant by refining echo time sampling and integrating multi-train blip-reversed EPI to enhance distortion correction and temporal SNR, enabling reliable extraction of subject-specific arterial input functions (AIFs). To support dynamic imaging, a steady-state Bloch simulation-based synthetic data framework was developed to simultaneously model T Results: Single-shot SAGE-MOLED demonstrated high consistency with standard methods in both phantom and in vivo experiments, with Pearson correlation coefficient = 0.991 for T Conclusion: SAGE-MOLED overcomes key limitations of SAGE-EPI, providing high-fidelity, distortion-corrected T (© 2025 International Society for Magnetic Resonance in Medicine.) |
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| Grant Information: | 2022YFC2402101 National Key R & D Program of China; 2022YFC2402102 National Key R & D Program of China; 2021Y9154 Science and Technology Project of Fujian Province of China; 12375291 National Natural Science Foundation of China; 22161142024 National Natural Science Foundation of China; 82071913 National Natural Science Foundation of China |
| Contributed Indexing: | Keywords: ... mapping; DCE; DSC; MOLED; T2 mapping |
| Entry Date(s): | Date Created: 20251102 Date Completed: 20260128 Latest Revision: 20260128 |
| Update Code: | 20260130 |
| DOI: | 10.1002/mrm.70165 |
| PMID: | 41177950 |
| Βάση Δεδομένων: | MEDLINE |
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