Academic Journal
Social experience shapes fighting strategies in Drosophila.
| Τίτλος: | Social experience shapes fighting strategies in Drosophila. |
|---|---|
| Συγγραφείς: | Gao C; The Key Laboratory of Developmental Genes and Human Disease, Jiangsu Key Laboratory of Brain Science and Medicine, School of Life Science and Technology, Southeast University, Nanjing, China., Ma M; The Key Laboratory of Developmental Genes and Human Disease, Jiangsu Key Laboratory of Brain Science and Medicine, School of Life Science and Technology, Southeast University, Nanjing, China., Chen J; The Key Laboratory of Developmental Genes and Human Disease, Jiangsu Key Laboratory of Brain Science and Medicine, School of Life Science and Technology, Southeast University, Nanjing, China., Ji X; The Key Laboratory of Developmental Genes and Human Disease, Jiangsu Key Laboratory of Brain Science and Medicine, School of Life Science and Technology, Southeast University, Nanjing, China., Peng Q; The Key Laboratory of Developmental Genes and Human Disease, Jiangsu Key Laboratory of Brain Science and Medicine, School of Life Science and Technology, Southeast University, Nanjing, China., Pan Y; The Key Laboratory of Developmental Genes and Human Disease, Jiangsu Key Laboratory of Brain Science and Medicine, School of Life Science and Technology, Southeast University, Nanjing, China.; Co-innovation Center of Neuroregeneration, Nantong University, Nantong, China. |
| Πηγή: | ELife [Elife] 2025 Oct 07; Vol. 13. Date of Electronic Publication: 2025 Oct 07. |
| Τύπος έκδοσης: | Journal Article |
| Γλώσσα: | English |
| Στοιχεία περιοδικού: | Publisher: eLife Sciences Publications, Ltd Country of Publication: England NLM ID: 101579614 Publication Model: Electronic Cited Medium: Internet ISSN: 2050-084X (Electronic) Linking ISSN: 2050084X NLM ISO Abbreviation: Elife Subsets: MEDLINE |
| Imprint Name(s): | Original Publication: Cambridge, UK : eLife Sciences Publications, Ltd., 2012- |
| Ιατρικοί όροι (MeSH): | Aggression*/physiology , Drosophila melanogaster*/physiology , Social Behavior* , Behavior, Animal*, Olfactory Receptor Neurons/physiology ; Animals ; Male ; Sexual Behavior, Animal ; Female |
| Περίληψη: | Social isolation generally increases aggression but decreases mating competition, resulting in an intricate and ambiguous relationship between social experience, aggression, and reproductive success. In male Drosophila, aggression is often characterized by lunging, a frequent and comparatively low-intensity combat behavior. Here, we provide a behavioral paradigm for studying a less frequent but more vigorous fighting form known as tussling. While social enrichment decreases lunging, aligning with past observations, it heightens the more forceful tussling behavior. These two forms of aggression rely on different olfactory receptor neurons, specifically Or67d for lunging and Or47b for tussling. We further identify three pairs of central pC1 neurons that specifically promote tussling. Moreover, shifting from lunging to tussling in socially enriched males is accompanied by better territory control and mating success. Our findings identify distinct sensory and central neurons for two fighting forms and suggest that social experience may shape fighting strategies to optimize reproductive success. (© 2024, Gao, Ma et al.) |
| Competing Interests: | CG, MM, JC, XJ, QP, YP No competing interests declared |
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| Grant Information: | 32371067 National Natural Science Foundation of China; 2021YFA1101300 National Key R&D Program of China; B2402005 Shenzhen Medical Academy of Research and Translation; BK20231418 Natural Science Foundation from Jiangsu Province; 2242023R40054 Fundamental Research Funds for the Central Universities |
| Contributed Indexing: | Keywords: D. melanogaster; Or47b ORNs; aggression; fighting strategies; neuroscience; pC1 neurons; reproductive competition; social experience |
| Entry Date(s): | Date Created: 20251007 Date Completed: 20251007 Latest Revision: 20251009 |
| Update Code: | 20260130 |
| PubMed Central ID: | PMC12503488 |
| DOI: | 10.7554/eLife.104212 |
| PMID: | 41055639 |
| Βάση Δεδομένων: | MEDLINE |
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