Academic Journal
Bacterial Contamination of Spacer Devices Used by Asthmatic Children: A Cross-Sectional Study.
| Τίτλος: | Bacterial Contamination of Spacer Devices Used by Asthmatic Children: A Cross-Sectional Study. |
|---|---|
| Συγγραφείς: | Kumar R; Department of Pediatrics, All India Institute of Medical Sciences (AIIMS) Jodhpur, Jodhpur, Rajasthan, 342005, India., Prabhakaran K; Department of Pediatrics, All India Institute of Medical Sciences (AIIMS) Jodhpur, Jodhpur, Rajasthan, 342005, India., Kumar P; Department of Pediatrics, All India Institute of Medical Sciences (AIIMS) Jodhpur, Jodhpur, Rajasthan, 342005, India., Tak V; Department of Microbiology, All India Institute of Medical Sciences (AIIMS) Jodhpur, Jodhpur, Rajasthan, 342005, India., Abhishek KS; Department of Microbiology, All India Institute of Medical Sciences (AIIMS) Jodhpur, Jodhpur, Rajasthan, 342005, India., Goyal JP; Department of Pediatrics, All India Institute of Medical Sciences (AIIMS) Jodhpur, Jodhpur, Rajasthan, 342005, India. jpgoyal@rediffmail.com. |
| Πηγή: | Indian pediatrics [Indian Pediatr] 2026 Jan; Vol. 63 (1), pp. 7-12. Date of Electronic Publication: 2025 Jul 28. |
| Τύπος έκδοσης: | Journal Article |
| Γλώσσα: | English |
| Στοιχεία περιοδικού: | Publisher: Indian Pediatrics Country of Publication: India NLM ID: 2985062R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 0974-7559 (Electronic) Linking ISSN: 00196061 NLM ISO Abbreviation: Indian Pediatr Subsets: MEDLINE |
| Imprint Name(s): | Publication: New Delhi : Indian Pediatrics Original Publication: Bombay. |
| Ιατρικοί όροι (MeSH): | Asthma*/drug therapy , Metered Dose Inhalers*/microbiology , Inhalation Spacers*/microbiology , Equipment Contamination*/statistics & numerical data , Bacteria*/isolation & purification, India/epidemiology ; Pseudomonas aeruginosa/isolation & purification ; Cross-Sectional Studies ; Humans ; Male ; Female ; Child, Preschool ; Child ; Adolescent ; Tertiary Care Centers ; Prevalence |
| Περίληψη: | Objective: To assess the prevalence of bacterial contamination of spacer devices used by asthmatic children. Methods: A cross-sectional study at a tertiary centre in India included asthmatic children aged 5 to 17 years who were using metered-dose inhaler (MDI) with a spacer for at least three months. A sterile cotton swab pre-moistened in sterile brain heart infusion (BHI) broth, rotated around the inner surface of the spacers, was smeared on blood agar and MacConkey agar plates. Plates were incubated for bacterial growth and examined for colony growth. Result: A total of 180 children were enrolled with a median (Q1, Q3) age of 12 (9, 14) years. Out of 180 spacer devices, 72 (40%) had pathogenic isolates and 108 (60%) had non-pathogenic isolates; Pseudomonas aeruginosa (28%) was the most common pathogenic bacteria. Only 17.8% (n = 32) were washing the spacer using soap and water; 84.4% (n = 152) patients used the air-dry method, and 15.6% (n = 28) dried the spacer using a cloth. There was no significant association between bacterial contamination and/or washing technique (P = 0.079). However, drying of spacer with a cloth was significantly associated with the growth of pathogenic bacteria as compared to air drying (P < 0.001). Bacterial contamination did not impact the asthma control (P = 0.491). Conclusion: A high prevalence of bacterial contamination of spacer devices was noted in asthmatic children, although it was not associated with asthma control. (© 2025. The Author(s), under exclusive licence to Indian Academy of Pediatrics.) |
| Competing Interests: | Declarations. Conflict of interest: None. Ethics Approval: Institutional Ethics Committee, AIIMS Jodhpur, Rajasthan; Ref No: IEC/2022/5298 dated Oct 07, 2022. |
| References: | Daniel RA, Aggarwal P, Kalaivani M, Gupta SK. Prevalence of asthma among children in India: a systematic review and meta-analysis. Lung India. 2022;39:357–67. (PMID: 10.4103/lungindia.lungindia_706_21358486699390309) Vincken W, Levy ML, Scullion J, Usmani OS, Dekhuijzen PNR, Corrigan CJ. Spacer devices for inhaled therapy: why use them, and how? ERJ Open Res. 2018;4: 00065–2018. (PMID: 10.1183/23120541.00065-2018299286496004521) Tay ET, Needleman JP, Avner JR. Nebulizer and spacer device maintenance in children with asthma. J Asthma. 2009;46:153–5. (PMID: 10.1080/0277090080253824419253121) Global Initiative for Asthma Management and Prevention, 2022. GINA Asthma. Available from: https://ginasthma.org/gina-reports/ . Accessed 21 Jun 2025. Thomas M, Kay S, Pike J, et al. The Asthma Control TestTM (ACT) as a predictor of GINA guideline-defined asthma control: analysis of a multinational cross-sectional survey. Prim Care Respir J. 2009;18:41–9. (PMID: 10.4104/pcrj.2009.00010192409486619040) Liu AH, Zeiger R, Sorkness C, et al. Development and cross-sectional validation of the Childhood Asthma Control Test. J Allergy Clin Immunol. 2007;119:817–25. (PMID: 10.1016/j.jaci.2006.12.66217353040) Cohen HA, Cohen Z, Pomeranz AS, Czitron B, Kahan E. Bacterial contamination of spacer devices used by asthmatic children. J Asthma. 2005;42:169–72. (PMID: 10.1081/JAS-5462515962872) Aschalew A, Kebed RA, Demie TG, Weldetsadik AY. Assessment of level of asthma control and related factors in children attending pediatric respiratory clinics in Addis Ababa, Ethiopia. BMC Pulm Med. 2022;22: 70. (PMID: 10.1186/s12890-022-01865-8351970328865488) Baddar S, Jayakrishnan B, Al-Rawas OA. Asthma control: importance of compliance and inhaler technique assessments. J Asthma. 2014;51:429–34. (PMID: 10.3109/02770903.2013.87155824304046) de Vries TW, Rienstra SR, van der Vorm ER. Bacterial contamination of inhalation chambers: results of a pilot study. J Aerosol Med Off J Int Soc Aerosols Med. 2004;17:354–6. (PMID: 10.1089/jam.2004.17.354) Cohen HA, Cohen Z, Kahan E. Bacterial contamination of spacer devices used by children with asthma. JAMA. 2003;290:195–6. (PMID: 10.1001/jama.290.2.19512851272) Shepherd MW, Hogan MB, Hayes R, Flesher S, Gillette C. Spacer microbial contamination and asthma outcomes: case series. J Asthma. 2022;59:755–6. (PMID: 10.1080/02770903.2020.187012833380230) Ribeiro JCDDC, Alves CDSF, Zarcos MM. Evaluation of inhaler use technique in a pediatric appointment. Pediatr Oncall [Internet]. 2022;19. Available from https://www.pediatriconcall.com/pediatric-journal/view/fulltext-articles/1377/J/0/0/751/0 . Accessed 14 Mar 2025. Asthma and Respiratory Foundation New Zealand, 2025. Available from https://www.asthmafoundation.org.nz/your-health/living-with-asthma/asthma-medication/how-to-use-your-asthma-inhaler-device/spacer . Accesed 21 Jun 2025. |
| Contributed Indexing: | Keywords: Air drying; Metered-dose inhaler; Respiratory pathogens; Spirometry; pMDI |
| Entry Date(s): | Date Created: 20250728 Date Completed: 20260401 Latest Revision: 20260608 |
| Update Code: | 20260609 |
| DOI: | 10.1007/s13312-025-00141-2 |
| PMID: | 40720072 |
| Βάση Δεδομένων: | MEDLINE |
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