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Sitting-rising test scores predict natural and cardiovascular causes of deaths in middle-aged and older men and women.

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Τίτλος: Sitting-rising test scores predict natural and cardiovascular causes of deaths in middle-aged and older men and women.
Συγγραφείς: Araújo CGS; Medical Department, Exercise Medicine Clinic-CLINIMEX, Rua Siqueira Campos, 93/101-103, Rio de Janeiro, RJ 22031071, Brazil., de Souza E Silva CG; Medical Department, Exercise Medicine Clinic-CLINIMEX, Rua Siqueira Campos, 93/101-103, Rio de Janeiro, RJ 22031071, Brazil., Myers J; Division of Cardiology, VA Palo Alto Health Care System and Stanford University, Palo Alto, USA., Laukkanen JA; Institute of Clinical Medicine, Department of Medicine, University of Eastern Finland, Kuopio, Finland.; Department of Medicine, Wellbeing Services County of Central Finland, Jyväskylä, Finland., Ramos PS; School of Medical and Health Sciences, SUPREMA, Juiz de Fora, Brazil., Ricardo DR; School of Medical and Health Sciences, SUPREMA, Juiz de Fora, Brazil.
Πηγή: European journal of preventive cardiology [Eur J Prev Cardiol] 2026 Sep 08; Vol. 33 (12), pp. 2170-2178.
Τύπος έκδοσης: Journal Article
Γλώσσα: English
Στοιχεία περιοδικού: Publisher: Oxford University Press Country of Publication: England NLM ID: 101564430 Publication Model: Print Cited Medium: Internet ISSN: 2047-4881 (Electronic) Linking ISSN: 20474873 NLM ISO Abbreviation: Eur J Prev Cardiol Subsets: MEDLINE
Imprint Name(s): Publication: 2021- : [Oxford] : Oxford University Press
Original Publication: London : Sage
Ιατρικοί όροι (MeSH): Cardiovascular Diseases*/mortality , Cardiovascular Diseases*/diagnosis , Cardiovascular Diseases*/physiopathology , Exercise Test*/methods , Sitting Position* , Physical Fitness*, Cause of Death/trends ; Humans ; Middle Aged ; Prospective Studies ; Aged ; Predictive Value of Tests ; Male ; Female ; Risk Assessment ; Time Factors ; Age Factors ; Prognosis ; Risk Factors ; Heart Disease Risk Factors ; Proportional Hazards Models
Περίληψη: Aims: In a previous study, the ability to sit and rise from the floor was associated with all-cause mortality. Now, we aim to assess whether sitting-rising test (SRT) scores also predict premature natural and cardiovascular (CV) deaths. This is a prospective cohort design study.
Methods and Results: A total of 4282 adults aged 46-75 years (68% men) performed sitting and rising from the floor, which was scored from 0 to 5, with one point being subtracted from 5 for each support used (hand/knee) and 0.5 for an unsteadiness execution. The final SRT score was obtained by adding sitting and rising scores and stratified in five groups for analysis: 0-4, 4.5-7.5, 8, 8.5-9.5, and 10. During a median follow-up of 12.3 (interquartile range = 7.6-18.0) years, there were 665 deaths (15.5%). There was a continuous trend for higher mortality with low SRT scores (P < 0.001), with death rates of 3.7, 7.0, 11.1, 20.4, and 42.1%, respectively, for Groups 5 to 1 of SRT scores. The Cox multivariate-adjusted (age, sex, body mass index, and clinical variables) hazard ratios of 3.84 [95% confidence interval (CI) 2.25-6.97] and 6.05 (95% CI 2.29-20.94) (P < 0.001) were observed, respectively, for natural and CV mortality, when comparing the highest and lowest SRT score groups.
Conclusion: Non-aerobic physical fitness, as assessed by SRT, was a significant predictor of natural and CV mortality in 46-75-year-old participants. Application of the SRT, a simple assessment tool that is influenced by muscular strength/power, flexibility, balance, and body composition, could add relevant clinical and prognostic information to routine examinations of healthy and unhealthy individuals.
(© The Author(s) 2025. Published by Oxford University Press on behalf of the European Society of Cardiology.)
Competing Interests: Conflict of interest: none declared.
Contributed Indexing: Keywords: CLINIMEX exercise cohort; Fitness testing; Older population; Physical fitness; Risk factors
Local Abstract: [plain-language-summary] From 1998 to 2023, 4282 individuals (46–75-year-old; 68% men) voluntarily participated in a medical evaluation focusing on physical fitness and health. None of them presented relevant physical or clinical limitations for fitness testing. All performed the sitting–rising test (SRT), aimed to safely evaluate, simultaneously, in the absence of equipment, the main components of non-aerobic physical fitness—muscle strength/power, flexibility, balance, and body composition. On the SRT, scores from 0 to 10 were attributed to the ability to sit and rise from the floor.This study expanded the findings of a previous study on the association of SRT scores and survival. Over a median follow-up of 12 years, 665 deaths (15.5% of the participants) due to natural causes (after excluding COVID-19 and external causes) occurred. Death rates were 3.7% for those having an SRT score of 10, tripled for 11.1% with an SRT score of 8 and dramatically increased by 42.1% in the 10% of participants with the lowest SRT score (0–4). After controlling for several covariates, we found a 3.8- and 6.0-fold higher risk for mortality, respectively, for natural and cardiovascular causes among those scoring 0–4 on the SRT when compared with those scoring a perfect 10, i.e. those able to sit and rise from the floor without using supports or exhibiting an unstable execution.Health professionals assessing non-aerobic fitness through SRT may have relevant subsides for a more individualized exercise prescription and to obtain clinically important prognostic information on survival for middle-aged and older healthy and unhealthy individuals.
Entry Date(s): Date Created: 20250626 Date Completed: 20260907 Latest Revision: 20260907
Update Code: 20260908
DOI: 10.1093/eurjpc/zwaf325
PMID: 40569873
Βάση Δεδομένων: MEDLINE
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  Data: Sitting-rising test scores predict natural and cardiovascular causes of deaths in middle-aged and older men and women.
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  Data: &lt;searchLink fieldCode=&quot;AU&quot; term=&quot;%22Ara&#250;jo+CGS%22&quot;&gt;Ara&#250;jo CGS&lt;/searchLink&gt;; Medical Department, Exercise Medicine Clinic-CLINIMEX, Rua Siqueira Campos, 93/101-103, Rio de Janeiro, RJ 22031071, Brazil.&lt;br /&gt;&lt;searchLink fieldCode=&quot;AU&quot; term=&quot;%22de+Souza+E+Silva+CG%22&quot;&gt;de Souza E Silva CG&lt;/searchLink&gt;; Medical Department, Exercise Medicine Clinic-CLINIMEX, Rua Siqueira Campos, 93/101-103, Rio de Janeiro, RJ 22031071, Brazil.&lt;br /&gt;&lt;searchLink fieldCode=&quot;AU&quot; term=&quot;%22Myers+J%22&quot;&gt;Myers J&lt;/searchLink&gt;; Division of Cardiology, VA Palo Alto Health Care System and Stanford University, Palo Alto, USA.&lt;br /&gt;&lt;searchLink fieldCode=&quot;AU&quot; term=&quot;%22Laukkanen+JA%22&quot;&gt;Laukkanen JA&lt;/searchLink&gt;; Institute of Clinical Medicine, Department of Medicine, University of Eastern Finland, Kuopio, Finland.; Department of Medicine, Wellbeing Services County of Central Finland, Jyv&#228;skyl&#228;, Finland.&lt;br /&gt;&lt;searchLink fieldCode=&quot;AU&quot; term=&quot;%22Ramos+PS%22&quot;&gt;Ramos PS&lt;/searchLink&gt;; School of Medical and Health Sciences, SUPREMA, Juiz de Fora, Brazil.&lt;br /&gt;&lt;searchLink fieldCode=&quot;AU&quot; term=&quot;%22Ricardo+DR%22&quot;&gt;Ricardo DR&lt;/searchLink&gt;; School of Medical and Health Sciences, SUPREMA, Juiz de Fora, Brazil.
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  Data: Aims: In a previous study, the ability to sit and rise from the floor was associated with all-cause mortality. Now, we aim to assess whether sitting-rising test (SRT) scores also predict premature natural and cardiovascular (CV) deaths. This is a prospective cohort design study.&lt;br /&gt;Methods and Results: A total of 4282 adults aged 46-75 years (68% men) performed sitting and rising from the floor, which was scored from 0 to 5, with one point being subtracted from 5 for each support used (hand/knee) and 0.5 for an unsteadiness execution. The final SRT score was obtained by adding sitting and rising scores and stratified in five groups for analysis: 0-4, 4.5-7.5, 8, 8.5-9.5, and 10. During a median follow-up of 12.3 (interquartile range = 7.6-18.0) years, there were 665 deaths (15.5%). There was a continuous trend for higher mortality with low SRT scores (P &amp;lt; 0.001), with death rates of 3.7, 7.0, 11.1, 20.4, and 42.1%, respectively, for Groups 5 to 1 of SRT scores. The Cox multivariate-adjusted (age, sex, body mass index, and clinical variables) hazard ratios of 3.84 [95% confidence interval (CI) 2.25-6.97] and 6.05 (95% CI 2.29-20.94) (P &amp;lt; 0.001) were observed, respectively, for natural and CV mortality, when comparing the highest and lowest SRT score groups.&lt;br /&gt;Conclusion: Non-aerobic physical fitness, as assessed by SRT, was a significant predictor of natural and CV mortality in 46-75-year-old participants. Application of the SRT, a simple assessment tool that is influenced by muscular strength/power, flexibility, balance, and body composition, could add relevant clinical and prognostic information to routine examinations of healthy and unhealthy individuals.&lt;br /&gt; (&#169; The Author(s) 2025. Published by Oxford University Press on behalf of the European Society of Cardiology.)
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  Label: Competing Interests
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  Data: Conflict of interest: none declared.
– Name: SubjectMinor
  Label: Contributed Indexing
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  Data: &lt;i&gt;Keywords: &lt;/i&gt;CLINIMEX exercise cohort; Fitness testing; Older population; Physical fitness; Risk factors&lt;br /&gt;&lt;i&gt;Local Abstract: &lt;/i&gt;[plain-language-summary] From 1998 to 2023, 4282 individuals (46–75-year-old; 68% men) voluntarily participated in a medical evaluation focusing on physical fitness and health. None of them presented relevant physical or clinical limitations for fitness testing. All performed the sitting–rising test (SRT), aimed to safely evaluate, simultaneously, in the absence of equipment, the main components of non-aerobic physical fitness—muscle strength/power, flexibility, balance, and body composition. On the SRT, scores from 0 to 10 were attributed to the ability to sit and rise from the floor.This study expanded the findings of a previous study on the association of SRT scores and survival. Over a median follow-up of 12 years, 665 deaths (15.5% of the participants) due to natural causes (after excluding COVID-19 and external causes) occurred. Death rates were 3.7% for those having an SRT score of 10, tripled for 11.1% with an SRT score of 8 and dramatically increased by 42.1% in the 10% of participants with the lowest SRT score (0–4). After controlling for several covariates, we found a 3.8- and 6.0-fold higher risk for mortality, respectively, for natural and cardiovascular causes among those scoring 0–4 on the SRT when compared with those scoring a perfect 10, i.e. those able to sit and rise from the floor without using supports or exhibiting an unstable execution.Health professionals assessing non-aerobic fitness through SRT may have relevant subsides for a more individualized exercise prescription and to obtain clinically important prognostic information on survival for middle-aged and older healthy and unhealthy individuals.
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        Value: 10.1093/eurjpc/zwaf325
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        Text: English
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        StartPage: 2170
    Subjects:
      – SubjectFull: Cause of Death trends
        Type: general
      – SubjectFull: Humans
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      – SubjectFull: Middle Aged
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              Text: 2026 Sep 08
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