Academic Journal
Elucidating the Effect of Dietary Laminarin on Striped Catfish (Pangasianodon hypophthalmus) Growth Performance, Histological Features, Immune-Antioxidant-Related Genes, and Resistance to Aeromonas hydrophila Infection.
| Τίτλος: | Elucidating the Effect of Dietary Laminarin on Striped Catfish (Pangasianodon hypophthalmus) Growth Performance, Histological Features, Immune-Antioxidant-Related Genes, and Resistance to Aeromonas hydrophila Infection. |
|---|---|
| Συγγραφείς: | Radwan M; Marine Biology Branch, Zoology Department, Faculty of Science, Al-Azhar University, Cairo, Egypt. MahmoudKhriy.201@azhar.edu.eg., Fares M; Zoology Department, Faculty of Science, Al-Azhar University, Cairo, Egypt., Al Malki JS; Department of Biology, College of Science, Taif University, Taif, Saudi Arabia., Mohammadein A; Department of Biology, College of Science, Taif University, Taif, Saudi Arabia., Moussa MA; Zoology Department, Faculty of Science, Cairo University, Cairo, Egypt. |
| Πηγή: | Probiotics and antimicrobial proteins [Probiotics Antimicrob Proteins] 2026 Jan; Vol. 18 (1), pp. 858-875. Date of Electronic Publication: 2025 May 13. |
| Τύπος έκδοσης: | Journal Article; Research Support, Non-U.S. Gov't |
| Γλώσσα: | English |
| Στοιχεία περιοδικού: | Publisher: Springer Country of Publication: United States NLM ID: 101484100 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1867-1314 (Electronic) Linking ISSN: 18671306 NLM ISO Abbreviation: Probiotics Antimicrob Proteins Subsets: MEDLINE |
| Imprint Name(s): | Original Publication: New York, NY. : Springer |
| Ιατρικοί όροι (MeSH): | Catfishes*/growth & development , Catfishes*/immunology , Catfishes*/microbiology , Catfishes*/genetics , Gram-Negative Bacterial Infections*/veterinary , Gram-Negative Bacterial Infections*/immunology , Gram-Negative Bacterial Infections*/microbiology , Fish Diseases*/immunology , Fish Diseases*/microbiology , Fish Diseases*/genetics , Glucans*/administration & dosage , Antioxidants*/metabolism, Aeromonas hydrophila/physiology ; Animal Feed/analysis ; Disease Resistance/drug effects ; Dietary Supplements/analysis ; Diet/veterinary ; Animals |
| Περίληψη: | Laminarin (LAM) contains immunostimulants and antioxidative macromolecules that help aquatic creatures function and stay healthy. In this regard, striped catfish (Pangasianodon hypophthalmus) with an initial weight of 21.66 ± 1.24 g for each fish and 15 fish per aquarium were placed in 24 glass aquariums (90 L each). Fish fed with LAM at 0, 200, 400, and 600 mg kg-1 represented as (L0, L1, L2, and L3) for 60 days were subsequently challenged with Aeromonas hydrophila. The findings demonstrated that the fish-administered dietary laminarin (DLAM) significantly (P < 0.001) boosted growth performance, intestinal health, and blood indices, particularly in fish-fed LAM at 400 and 600 mg kg-1. In comparison to the control group, the fish-fed DLAM displayed a significant (P < 0.001) decrease in MDA value and a rise in antioxidant (SOD, GPx, and CAT) and immunological indices (Lysozyme activity, phagocytic activity, and Complement C3), particularly with higher LAM doses. When compared to other groups, fish fed LAM at 400 and 600 mg kg-1 diet showed increased significant (P < 0.001) levels of SOD, GPx, and CAT genes, while HSP70, IL-1β, and TNF gene expression decreased. According to the histological study, all tissues assessed in fish fed with LAM showed intact structural improvements with increasing DLAM supplementation. Following an A. hydrophila infection challenge, fish groups fed DLAM, specifically 600 mg kg-1, had significantly better survival rates than fish in the control group. As a result, the study found that the study found that striped catfish require 247.6 to 458 mg kg-1 of DLAM to exhibit optimal growth performance, blood indices, antioxidative, immunological response, and infection resistance. (© 2025. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.) |
| Competing Interests: | Declarations. Consent to Participate: All of the authors consent to participate in the study above. Consent for Publication: Not applicable. Conflict of Interest: The authors declare no competing interests. |
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| Contributed Indexing: | Keywords: Antioxidants; Aquaculture; Digestion; Health condition; Immunostimulants |
| Substance Nomenclature: | 0 (Glucans) 9008-22-4 (laminaran) 0 (Antioxidants) |
| Entry Date(s): | Date Created: 20250512 Date Completed: 20260319 Latest Revision: 20261016 |
| Update Code: | 20261017 |
| DOI: | 10.1007/s12602-025-10566-7 |
| PMID: | 40355779 |
| Βάση Δεδομένων: | MEDLINE |
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