Academic Journal
Understanding anxiety through uncertainty quantification.
| Τίτλος: | Understanding anxiety through uncertainty quantification. |
|---|---|
| Συγγραφείς: | Hedley FE; Department of Psychology, The University of Hong Kong, Hong Kong SAR, China., Larsen E; Department of Psychology, Stony Brook University, Stony Brook, New York, USA., Mohanty A; Department of Psychology, Stony Brook University, Stony Brook, New York, USA., Liu JZ; Google Research, Mountain View, California, USA.; Department of Biostatistics, Harvard University, Boston, Massachusetts, USA., Jin J; Department of Psychology, The University of Hong Kong, Hong Kong SAR, China.; State Key Laboratory of Brain and Cognitive Sciences, The University of Hong Kong, Hong Kong SAR, China. |
| Πηγή: | British journal of psychology (London, England : 1953) [Br J Psychol] 2026 Aug; Vol. 117 (3), pp. 795-808. Date of Electronic Publication: 2024 Jan 12. |
| Τύπος έκδοσης: | Journal Article |
| Γλώσσα: | English |
| Στοιχεία περιοδικού: | Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 0373124 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2044-8295 (Electronic) Linking ISSN: 00071269 NLM ISO Abbreviation: Br J Psychol Subsets: MEDLINE |
| Imprint Name(s): | Publication: 2011- : West Sussex, England : Wiley-Blackwell Original Publication: London ; New York : Cambridge University Press, [1953]- |
| Ιατρικοί όροι (MeSH): | Anxiety*/psychology , Anxiety*/physiopathology, Humans ; Bayes Theorem ; Uncertainty |
| Περίληψη: | Uncertainty has been a central concept in psychological theories of anxiety. However, this concept has been plagued by divergent connotations and operationalizations. The lack of consensus hinders the current search for cognitive and biological mechanisms of anxiety, jeopardizes theory creation and comparison, and restrains translation of basic research into improved diagnoses and interventions. Drawing upon uncertainty decomposition in Bayesian Decision Theory, we propose a well-defined conceptual structure of uncertainty in cognitive and clinical sciences, with a focus on anxiety. We discuss how this conceptual structure provides clarity and can be naturally applied to existing frameworks of psychopathology research. Furthermore, it allows formal quantification of various types of uncertainty that can benefit both research and clinical practice in the era of computational psychiatry. (© 2024 The British Psychological Society.) |
| References: | Behav Res Ther. 2002 Aug;40(8):931-45. (PMID: 12186356) PLoS Comput Biol. 2021 Oct 7;17(10):e1009453. (PMID: 34618805) Am Psychol. 2000 Nov;55(11):1247-63. (PMID: 11280938) Clin Psychol Rev. 2018 Mar;60:87-99. (PMID: 29331446) Decision (Wash D C ). 2024 Apr;11(2):255-282. (PMID: 40162322) Affect Sci. 2022;3(2):425-437. (PMID: 35791419) Neuroimage. 2020 Sep;218:116957. (PMID: 32442639) J Exp Psychol Gen. 2016 Oct;145(10):1280-1297. (PMID: 27442037) J Neurol Neurosurg Psychiatry. 2019 Dec;90(12):1353-1360. (PMID: 31256001) Biol Psychiatry. 2012 Jul 15;72(2):113-8. (PMID: 22325982) Nat Commun. 2021 Nov 15;12(1):6587. (PMID: 34782597) Biol Psychiatry. 2017 Jun 15;81(12):1014-1022. (PMID: 28126210) Annu Rev Clin Psychol. 2013;9:275-97. (PMID: 23537486) Emotion. 2022 Aug;22(5):982-991. (PMID: 32881546) R Soc Open Sci. 2019 May 8;6(5):181870. (PMID: 31218028) Int J Psychophysiol. 2020 Oct;156:93-104. (PMID: 32763250) Am Psychol. 2019 May-Jun;74(4):484-496. (PMID: 30221947) Am J Psychiatry. 2010 Jul;167(7):748-51. (PMID: 20595427) Elife. 2020 Dec 22;9:. (PMID: 33350387) J Affect Disord. 2018 Jan 1;225:80-90. (PMID: 28802117) Clin Psychol Rev. 2019 Nov;73:101778. (PMID: 31678816) Affect Sci. 2022 Jun 3;3(3):528-538. (PMID: 35677191) Psychophysiology. 2018 Jul;55(7):e13066. (PMID: 29384197) Nat Rev Neurosci. 2010 Feb;11(2):127-38. (PMID: 20068583) Psychol Assess. 2015 Jun;27(2):605-20. (PMID: 25602690) Behav Res Ther. 1983;21(1):9-16. (PMID: 6830571) Neurosci Biobehav Rev. 2023 May;148:105123. (PMID: 36914079) Comput Psychiatr. 2022;6(1):8-33. (PMID: 35757373) Pers Individ Dif. 2009;46(5-6):586-591. (PMID: 20046938) J Neurosci. 2011 Mar 30;31(13):4811-20. (PMID: 21451019) Behav Res Ther. 2007 Oct;45(10):2307-16. (PMID: 17537402) J Anxiety Disord. 2007;21(1):105-17. (PMID: 16647833) Nat Neurosci. 2016 Mar;19(3):404-13. (PMID: 26906507) Nat Neurosci. 2008 Apr;11(4):398-403. (PMID: 18368046) Neurosci Biobehav Rev. 2019 Jan;96:241-249. (PMID: 30550858) J Psychopathol Clin Sci. 2022 Apr;131(3):265-277. (PMID: 35357845) Cereb Cortex. 2013 Jan;23(1):49-60. (PMID: 22250290) J Neurosci. 2020 Oct 7;40(41):7949-7964. (PMID: 32958570) World Psychiatry. 2018 Jun;17(2):123-132. (PMID: 29856567) Pers Soc Psychol Rev. 2016 Aug;20(3):223-44. (PMID: 26048875) Nat Hum Behav. 2019 Oct;3(10):1116-1123. (PMID: 31209369) Nat Rev Neurosci. 2013 Jul;14(7):488-501. (PMID: 23783199) Emotion. 2009 Feb;9(1):123-7. (PMID: 19186925) Biol Psychiatry. 2017 Sep 15;82(6):382-384. (PMID: 28838466) J Comp Neurol. 2020 Jun;528(8):1265-1292. (PMID: 31674015) Annu Rev Clin Psychol. 2020 May 7;16:49-74. (PMID: 32070120) Nat Commun. 2024 Oct 21;15(1):9073. (PMID: 39433765) Expert Rev Neurother. 2012 Aug;12(8):937-47. (PMID: 23002938) Clin Psychol Rev. 2017 Jun;54:107-122. (PMID: 28448826) Nat Protoc. 2012 Feb 23;7(3):527-32. (PMID: 22362158) J Anxiety Disord. 2021 Jan;77:102332. (PMID: 33160276) Front Psychol. 2012 Mar 08;3:54. (PMID: 22408629) J Anxiety Disord. 2016 Apr;39:30-43. (PMID: 26945765) Trends Cogn Sci. 2019 Oct;23(10):865-875. (PMID: 31431340) |
| Contributed Indexing: | Keywords: Bayesian theory; anxiety; intolerance of uncertainty; research domain criteria; uncertainty quantification |
| Entry Date(s): | Date Created: 20240112 Date Completed: 20260710 Latest Revision: 20260813 |
| Update Code: | 20260813 |
| PubMed Central ID: | PMC13353260 |
| DOI: | 10.1111/bjop.12693 |
| PMID: | 38217080 |
| Βάση Δεδομένων: | MEDLINE |
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| Items | – Name: Title Label: Title Group: Ti Data: Understanding anxiety through uncertainty quantification. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Hedley+FE%22">Hedley FE</searchLink>; Department of Psychology, The University of Hong Kong, Hong Kong SAR, China.<br /><searchLink fieldCode="AU" term="%22Larsen+E%22">Larsen E</searchLink>; Department of Psychology, Stony Brook University, Stony Brook, New York, USA.<br /><searchLink fieldCode="AU" term="%22Mohanty+A%22">Mohanty A</searchLink>; Department of Psychology, Stony Brook University, Stony Brook, New York, USA.<br /><searchLink fieldCode="AU" term="%22Liu+JZ%22">Liu JZ</searchLink>; Google Research, Mountain View, California, USA.; Department of Biostatistics, Harvard University, Boston, Massachusetts, USA.<br /><searchLink fieldCode="AU" term="%22Jin+J%22">Jin J</searchLink>; Department of Psychology, The University of Hong Kong, Hong Kong SAR, China.; State Key Laboratory of Brain and Cognitive Sciences, The University of Hong Kong, Hong Kong SAR, China. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%220373124%22">British journal of psychology (London, England : 1953)</searchLink> [Br J Psychol] 2026 Aug; Vol. 117 (3), pp. 795-808. <i>Date of Electronic Publication: </i>2024 Jan 12. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article – Name: Language Label: Language Group: Lang Data: English – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Wiley-Blackwell%22">Wiley-Blackwell </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>0373124 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2044-8295 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200071269%22">00071269 </searchLink><i>NLM ISO Abbreviation: </i>Br J Psychol <i>Subsets: </i>MEDLINE – Name: PublisherInfo Label: Imprint Name(s) Group: PubInfo Data: <i>Publication</i>: 2011- : West Sussex, England : Wiley-Blackwell<br /><i>Original Publication</i>: London ; New York : Cambridge University Press, [1953]- – Name: SubjectMESH Label: MeSH Terms Group: Su Data: <searchLink fieldCode="MM" term="%22Anxiety%22">Anxiety*</searchLink>/<searchLink fieldCode="MM" term="%22Anxiety+psychology%22">psychology</searchLink> <br /><searchLink fieldCode="MM" term="%22Anxiety%22">Anxiety*</searchLink>/<searchLink fieldCode="MM" term="%22Anxiety+physiopathology%22">physiopathology</searchLink><br /><searchLink fieldCode="MH" term="%22Humans%22">Humans</searchLink> ; <searchLink fieldCode="MH" term="%22Bayes+Theorem%22">Bayes Theorem</searchLink> ; <searchLink fieldCode="MH" term="%22Uncertainty%22">Uncertainty</searchLink> – Name: Abstract Label: Abstract Group: Ab Data: Uncertainty has been a central concept in psychological theories of anxiety. However, this concept has been plagued by divergent connotations and operationalizations. The lack of consensus hinders the current search for cognitive and biological mechanisms of anxiety, jeopardizes theory creation and comparison, and restrains translation of basic research into improved diagnoses and interventions. Drawing upon uncertainty decomposition in Bayesian Decision Theory, we propose a well-defined conceptual structure of uncertainty in cognitive and clinical sciences, with a focus on anxiety. We discuss how this conceptual structure provides clarity and can be naturally applied to existing frameworks of psychopathology research. Furthermore, it allows formal quantification of various types of uncertainty that can benefit both research and clinical practice in the era of computational psychiatry.<br /> (© 2024 The British Psychological Society.) – Name: Ref Label: References Group: RefInfo Data: Behav Res Ther. 2002 Aug;40(8):931-45. (PMID: <searchLink fieldCode="PM" term="%2212186356%22">12186356)</searchLink><br />PLoS Comput Biol. 2021 Oct 7;17(10):e1009453. (PMID: <searchLink fieldCode="PM" term="%2234618805%22">34618805)</searchLink><br />Am Psychol. 2000 Nov;55(11):1247-63. (PMID: <searchLink fieldCode="PM" term="%2211280938%22">11280938)</searchLink><br />Clin Psychol Rev. 2018 Mar;60:87-99. (PMID: <searchLink fieldCode="PM" term="%2229331446%22">29331446)</searchLink><br />Decision (Wash D C ). 2024 Apr;11(2):255-282. (PMID: <searchLink fieldCode="PM" term="%2240162322%22">40162322)</searchLink><br />Affect Sci. 2022;3(2):425-437. (PMID: <searchLink fieldCode="PM" term="%2235791419%22">35791419)</searchLink><br />Neuroimage. 2020 Sep;218:116957. (PMID: <searchLink fieldCode="PM" term="%2232442639%22">32442639)</searchLink><br />J Exp Psychol Gen. 2016 Oct;145(10):1280-1297. (PMID: <searchLink fieldCode="PM" term="%2227442037%22">27442037)</searchLink><br />J Neurol Neurosurg Psychiatry. 2019 Dec;90(12):1353-1360. (PMID: <searchLink fieldCode="PM" term="%2231256001%22">31256001)</searchLink><br />Biol Psychiatry. 2012 Jul 15;72(2):113-8. (PMID: <searchLink fieldCode="PM" term="%2222325982%22">22325982)</searchLink><br />Nat Commun. 2021 Nov 15;12(1):6587. (PMID: <searchLink fieldCode="PM" term="%2234782597%22">34782597)</searchLink><br />Biol Psychiatry. 2017 Jun 15;81(12):1014-1022. (PMID: <searchLink fieldCode="PM" term="%2228126210%22">28126210)</searchLink><br />Annu Rev Clin Psychol. 2013;9:275-97. (PMID: <searchLink fieldCode="PM" term="%2223537486%22">23537486)</searchLink><br />Emotion. 2022 Aug;22(5):982-991. (PMID: <searchLink fieldCode="PM" term="%2232881546%22">32881546)</searchLink><br />R Soc Open Sci. 2019 May 8;6(5):181870. (PMID: <searchLink fieldCode="PM" term="%2231218028%22">31218028)</searchLink><br />Int J Psychophysiol. 2020 Oct;156:93-104. (PMID: <searchLink fieldCode="PM" term="%2232763250%22">32763250)</searchLink><br />Am Psychol. 2019 May-Jun;74(4):484-496. (PMID: <searchLink fieldCode="PM" term="%2230221947%22">30221947)</searchLink><br />Am J Psychiatry. 2010 Jul;167(7):748-51. (PMID: <searchLink fieldCode="PM" term="%2220595427%22">20595427)</searchLink><br />Elife. 2020 Dec 22;9:. (PMID: <searchLink fieldCode="PM" term="%2233350387%22">33350387)</searchLink><br />J Affect Disord. 2018 Jan 1;225:80-90. (PMID: <searchLink fieldCode="PM" term="%2228802117%22">28802117)</searchLink><br />Clin Psychol Rev. 2019 Nov;73:101778. (PMID: <searchLink fieldCode="PM" term="%2231678816%22">31678816)</searchLink><br />Affect Sci. 2022 Jun 3;3(3):528-538. (PMID: <searchLink fieldCode="PM" term="%2235677191%22">35677191)</searchLink><br />Psychophysiology. 2018 Jul;55(7):e13066. (PMID: <searchLink fieldCode="PM" term="%2229384197%22">29384197)</searchLink><br />Nat Rev Neurosci. 2010 Feb;11(2):127-38. (PMID: <searchLink fieldCode="PM" term="%2220068583%22">20068583)</searchLink><br />Psychol Assess. 2015 Jun;27(2):605-20. (PMID: <searchLink fieldCode="PM" term="%2225602690%22">25602690)</searchLink><br />Behav Res Ther. 1983;21(1):9-16. (PMID: <searchLink fieldCode="PM" term="%226830571%22">6830571)</searchLink><br />Neurosci Biobehav Rev. 2023 May;148:105123. (PMID: <searchLink fieldCode="PM" term="%2236914079%22">36914079)</searchLink><br />Comput Psychiatr. 2022;6(1):8-33. (PMID: <searchLink fieldCode="PM" term="%2235757373%22">35757373)</searchLink><br />Pers Individ Dif. 2009;46(5-6):586-591. (PMID: <searchLink fieldCode="PM" term="%2220046938%22">20046938)</searchLink><br />J Neurosci. 2011 Mar 30;31(13):4811-20. (PMID: <searchLink fieldCode="PM" term="%2221451019%22">21451019)</searchLink><br />Behav Res Ther. 2007 Oct;45(10):2307-16. (PMID: <searchLink fieldCode="PM" term="%2217537402%22">17537402)</searchLink><br />J Anxiety Disord. 2007;21(1):105-17. (PMID: <searchLink fieldCode="PM" term="%2216647833%22">16647833)</searchLink><br />Nat Neurosci. 2016 Mar;19(3):404-13. (PMID: <searchLink fieldCode="PM" term="%2226906507%22">26906507)</searchLink><br />Nat Neurosci. 2008 Apr;11(4):398-403. (PMID: <searchLink fieldCode="PM" term="%2218368046%22">18368046)</searchLink><br />Neurosci Biobehav Rev. 2019 Jan;96:241-249. (PMID: <searchLink fieldCode="PM" term="%2230550858%22">30550858)</searchLink><br />J Psychopathol Clin Sci. 2022 Apr;131(3):265-277. (PMID: <searchLink fieldCode="PM" term="%2235357845%22">35357845)</searchLink><br />Cereb Cortex. 2013 Jan;23(1):49-60. (PMID: <searchLink fieldCode="PM" term="%2222250290%22">22250290)</searchLink><br />J Neurosci. 2020 Oct 7;40(41):7949-7964. (PMID: <searchLink fieldCode="PM" term="%2232958570%22">32958570)</searchLink><br />World Psychiatry. 2018 Jun;17(2):123-132. (PMID: <searchLink fieldCode="PM" term="%2229856567%22">29856567)</searchLink><br />Pers Soc Psychol Rev. 2016 Aug;20(3):223-44. (PMID: <searchLink fieldCode="PM" term="%2226048875%22">26048875)</searchLink><br />Nat Hum Behav. 2019 Oct;3(10):1116-1123. (PMID: <searchLink fieldCode="PM" term="%2231209369%22">31209369)</searchLink><br />Nat Rev Neurosci. 2013 Jul;14(7):488-501. (PMID: <searchLink fieldCode="PM" term="%2223783199%22">23783199)</searchLink><br />Emotion. 2009 Feb;9(1):123-7. (PMID: <searchLink fieldCode="PM" term="%2219186925%22">19186925)</searchLink><br />Biol Psychiatry. 2017 Sep 15;82(6):382-384. (PMID: <searchLink fieldCode="PM" term="%2228838466%22">28838466)</searchLink><br />J Comp Neurol. 2020 Jun;528(8):1265-1292. (PMID: <searchLink fieldCode="PM" term="%2231674015%22">31674015)</searchLink><br />Annu Rev Clin Psychol. 2020 May 7;16:49-74. (PMID: <searchLink fieldCode="PM" term="%2232070120%22">32070120)</searchLink><br />Nat Commun. 2024 Oct 21;15(1):9073. (PMID: <searchLink fieldCode="PM" term="%2239433765%22">39433765)</searchLink><br />Expert Rev Neurother. 2012 Aug;12(8):937-47. (PMID: <searchLink fieldCode="PM" term="%2223002938%22">23002938)</searchLink><br />Clin Psychol Rev. 2017 Jun;54:107-122. (PMID: <searchLink fieldCode="PM" term="%2228448826%22">28448826)</searchLink><br />Nat Protoc. 2012 Feb 23;7(3):527-32. (PMID: <searchLink fieldCode="PM" term="%2222362158%22">22362158)</searchLink><br />J Anxiety Disord. 2021 Jan;77:102332. (PMID: <searchLink fieldCode="PM" term="%2233160276%22">33160276)</searchLink><br />Front Psychol. 2012 Mar 08;3:54. (PMID: <searchLink fieldCode="PM" term="%2222408629%22">22408629)</searchLink><br />J Anxiety Disord. 2016 Apr;39:30-43. (PMID: <searchLink fieldCode="PM" term="%2226945765%22">26945765)</searchLink><br />Trends Cogn Sci. 2019 Oct;23(10):865-875. 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| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1111/bjop.12693 Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: 795 Subjects: – SubjectFull: Humans Type: general – SubjectFull: Bayes Theorem Type: general – SubjectFull: Uncertainty Type: general – SubjectFull: Anxiety psychology Type: general – SubjectFull: Anxiety physiopathology Type: general Titles: – TitleFull: Understanding anxiety through uncertainty quantification. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Hedley FE – PersonEntity: Name: NameFull: Larsen E – PersonEntity: Name: NameFull: Mohanty A – PersonEntity: Name: NameFull: Liu JZ – PersonEntity: Name: NameFull: Jin J IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 08 Text: 2026 Aug Type: published Y: 2026 Identifiers: – Type: issn-electronic Value: 2044-8295 Numbering: – Type: volume Value: 117 – Type: issue Value: 3 Titles: – TitleFull: British journal of psychology (London, England : 1953) Type: main |
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