Academic Journal

Large Language Models in Neurology Research and Future Practice.

Λεπτομέρειες βιβλιογραφικής εγγραφής
Τίτλος: Large Language Models in Neurology Research and Future Practice.
Συγγραφείς: Romano MF; From the Department of Medicine (M.F.R., R.A., V.B.K.), Boston University Chobanian & Avedisian School of Medicine, MA; Department of Radiology and Biomedical Imaging (M.F.R.), University of California, San Francisco; Department of Neurology (L.C.S., R.A.), Boston University Chobanian & Avedisian School of Medicine; Department of Electrical and Computer Engineering (I.C.P.), Division of Systems Engineering, and Department of Biomedical Engineering; Faculty of Computing and Data Sciences (I.C.P., V.B.K.), Boston University; Department of Anatomy and Neurobiology (R.A.); The Framingham Heart Study, Boston University Chobanian & Avedisian School of Medicine; Department of Epidemiology, Boston University School of Public Health; Boston University Alzheimer's Disease Research Center (R.A.); and Department of Computer Science (V.B.K.), Boston University, MA., Shih LC; From the Department of Medicine (M.F.R., R.A., V.B.K.), Boston University Chobanian & Avedisian School of Medicine, MA; Department of Radiology and Biomedical Imaging (M.F.R.), University of California, San Francisco; Department of Neurology (L.C.S., R.A.), Boston University Chobanian & Avedisian School of Medicine; Department of Electrical and Computer Engineering (I.C.P.), Division of Systems Engineering, and Department of Biomedical Engineering; Faculty of Computing and Data Sciences (I.C.P., V.B.K.), Boston University; Department of Anatomy and Neurobiology (R.A.); The Framingham Heart Study, Boston University Chobanian & Avedisian School of Medicine; Department of Epidemiology, Boston University School of Public Health; Boston University Alzheimer's Disease Research Center (R.A.); and Department of Computer Science (V.B.K.), Boston University, MA., Paschalidis IC; From the Department of Medicine (M.F.R., R.A., V.B.K.), Boston University Chobanian & Avedisian School of Medicine, MA; Department of Radiology and Biomedical Imaging (M.F.R.), University of California, San Francisco; Department of Neurology (L.C.S., R.A.), Boston University Chobanian & Avedisian School of Medicine; Department of Electrical and Computer Engineering (I.C.P.), Division of Systems Engineering, and Department of Biomedical Engineering; Faculty of Computing and Data Sciences (I.C.P., V.B.K.), Boston University; Department of Anatomy and Neurobiology (R.A.); The Framingham Heart Study, Boston University Chobanian & Avedisian School of Medicine; Department of Epidemiology, Boston University School of Public Health; Boston University Alzheimer's Disease Research Center (R.A.); and Department of Computer Science (V.B.K.), Boston University, MA., Au R; From the Department of Medicine (M.F.R., R.A., V.B.K.), Boston University Chobanian & Avedisian School of Medicine, MA; Department of Radiology and Biomedical Imaging (M.F.R.), University of California, San Francisco; Department of Neurology (L.C.S., R.A.), Boston University Chobanian & Avedisian School of Medicine; Department of Electrical and Computer Engineering (I.C.P.), Division of Systems Engineering, and Department of Biomedical Engineering; Faculty of Computing and Data Sciences (I.C.P., V.B.K.), Boston University; Department of Anatomy and Neurobiology (R.A.); The Framingham Heart Study, Boston University Chobanian & Avedisian School of Medicine; Department of Epidemiology, Boston University School of Public Health; Boston University Alzheimer's Disease Research Center (R.A.); and Department of Computer Science (V.B.K.), Boston University, MA., Kolachalama VB; From the Department of Medicine (M.F.R., R.A., V.B.K.), Boston University Chobanian & Avedisian School of Medicine, MA; Department of Radiology and Biomedical Imaging (M.F.R.), University of California, San Francisco; Department of Neurology (L.C.S., R.A.), Boston University Chobanian & Avedisian School of Medicine; Department of Electrical and Computer Engineering (I.C.P.), Division of Systems Engineering, and Department of Biomedical Engineering; Faculty of Computing and Data Sciences (I.C.P., V.B.K.), Boston University; Department of Anatomy and Neurobiology (R.A.); The Framingham Heart Study, Boston University Chobanian & Avedisian School of Medicine; Department of Epidemiology, Boston University School of Public Health; Boston University Alzheimer's Disease Research Center (R.A.); and Department of Computer Science (V.B.K.), Boston University, MA. vkola@bu.edu.
Πηγή: Neurology [Neurology] 2023 Dec 04; Vol. 101 (23), pp. 1058-1067. Date of Electronic Publication: 2023 Dec 04.
Τύπος έκδοσης: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, N.I.H., Extramural
Γλώσσα: English
Στοιχεία περιοδικού: Publisher: Lippincott Williams & Wilkins Country of Publication: United States NLM ID: 0401060 Publication Model: Electronic Cited Medium: Internet ISSN: 1526-632X (Electronic) Linking ISSN: 00283878 NLM ISO Abbreviation: Neurology Subsets: MEDLINE
Imprint Name(s): Publication: Hagerstown, MD : Lippincott Williams & Wilkins
Original Publication: Minneapolis.
Ιατρικοί όροι (MeSH): Artificial Intelligence* , Neurology*, Humans ; Language ; Medical Records ; Research Personnel
Περίληψη: Recent advancements in generative artificial intelligence, particularly using large language models (LLMs), are gaining increased public attention. We provide a perspective on the potential of LLMs to analyze enormous amounts of data from medical records and gain insights on specific topics in neurology. In addition, we explore use cases for LLMs, such as early diagnosis, supporting patient and caregivers, and acting as an assistant for clinicians. We point to the potential ethical and technical challenges raised by LLMs, such as concerns about privacy and data security, potential biases in the data for model training, and the need for careful validation of results. Researchers must consider these challenges and take steps to address them to ensure that their work is conducted in a safe and responsible manner. Despite these challenges, LLMs offer promising opportunities for improving care and treatment of various neurologic disorders.
(Copyright © 2023 The Author(s). Published by Wolters Kluwer Health, Inc. on behalf of the American Academy of Neurology.)
References: J Am Med Inform Assoc. 2022 Apr 13;29(5):873-881. (PMID: 35190834)
Yearb Med Inform. 2021 Aug;30(1):239-244. (PMID: 34479396)
Stroke Vasc Neurol. 2017 Jun 21;2(4):230-243. (PMID: 29507784)
Int J Methods Psychiatr Res. 2016 Jun;25(2):86-100. (PMID: 26184780)
JMIR Med Inform. 2020 Mar 31;8(3):e17984. (PMID: 32229465)
Artif Intell Med. 2021 Jul;117:102083. (PMID: 34127232)
PLoS One. 2018 Feb 15;13(2):e0192360. (PMID: 29447188)
Br J Psychiatry. 2022 May;220(5):251-253. (PMID: 35048814)
J Med Internet Res. 2021 May 4;23(5):e15708. (PMID: 33944788)
Cell Rep Med. 2022 Jan 18;3(1):100485. (PMID: 35106506)
Nat Med. 2023 Aug;29(8):1930-1940. (PMID: 37460753)
J Med Internet Res. 2021 Jan 27;23(1):e25113. (PMID: 33502324)
Crit Care. 2023 Apr 18;27(1):148. (PMID: 37072798)
Ann Emerg Med. 2023 Mar;81(3):262-269. (PMID: 36328850)
Expert Syst Appl. 2023 Mar 15;214:. (PMID: 36865787)
Circulation. 2000 Jun 13;101(23):E215-20. (PMID: 10851218)
N Engl J Med. 2023 Mar 30;388(13):1233-1239. (PMID: 36988602)
J Biomed Inform. 2022 Feb;126:103982. (PMID: 34974190)
PLOS Digit Health. 2022 Dec 22;1(12):e0000168. (PMID: 36812634)
Lancet. 2023 Feb 25;401(10377):641. (PMID: 36841609)
NPJ Digit Med. 2023 Jul 6;6(1):120. (PMID: 37414860)
Front Psychiatry. 2022 Sep 14;13:946387. (PMID: 36186874)
J Am Med Inform Assoc. 2013 Sep-Oct;20(5):980-5. (PMID: 23666777)
Lancet Digit Health. 2023 Mar;5(3):e102. (PMID: 36754723)
J Biomed Inform. 2019 Jun;94:103207. (PMID: 31077817)
Nature. 2023 Mar;615(7954):773. (PMID: 36928404)
J Biomed Inform. 2023 Apr;140:104336. (PMID: 36958461)
Nat Med. 2023 Oct;29(10):2396-2398. (PMID: 37391665)
JAMA Intern Med. 2023 Jun 1;183(6):589-596. (PMID: 37115527)
Epilepsy Behav. 2019 Dec;101(Pt B):106457. (PMID: 31444029)
JAMA. 2023 Jul 25;330(4):315-316. (PMID: 37410482)
Alzheimers Dement. 2023 Mar;19(3):946-955. (PMID: 35796399)
Arch Clin Neuropsychol. 2008 May;23(3):229-41. (PMID: 18339515)
Comput Intell Neurosci. 2022 Jun 9;2022:1883698. (PMID: 35720939)
JMIR Neurotechnol. 2024 May 22;3:e51822. (PMID: 41341247)
Comput Biol Med. 2021 Feb;129:104130. (PMID: 33271399)
Nature. 2023 Aug;620(7973):E19. (PMID: 37500979)
Curr Opin Neurol. 2019 Dec;32(6):850-856. (PMID: 31609739)
J Biomed Inform. 2023 Jul;143:104392. (PMID: 37211194)
Epilepsia. 2023 Feb;64(2):292-305. (PMID: 36462150)
Cancer Res. 2019 Nov 1;79(21):5463-5470. (PMID: 31395609)
Grant Information: RF1 AG062109 United States AG NIA NIH HHS; R01 HL159620 United States HL NHLBI NIH HHS; R21 CA253498 United States CA NCI NIH HHS; R43 DK134273 United States DK NIDDK NIH HHS; RF1 AG072654 United States AG NIA NIH HHS; U19 AG068753 United States AG NIA NIH HHS; P30 AG013846 United States AG NIA NIH HHS
Entry Date(s): Date Created: 20231010 Date Completed: 20231206 Latest Revision: 20260922
Update Code: 20260922
PubMed Central ID: PMC10752640
DOI: 10.1212/WNL.0000000000207967
PMID: 37816646
Βάση Δεδομένων: MEDLINE