Academic Journal

Results of in vitro fertilization after diagnosis and treatment of chronic endometritis.

Λεπτομέρειες βιβλιογραφικής εγγραφής
Τίτλος: Results of in vitro fertilization after diagnosis and treatment of chronic endometritis.
Συγγραφείς: Vaduva CC; Department of Obstetrics and Gynecology, University of Medicine and Pharmacy of Craiova, Craiova, Romania. hitmed@gmail.com., Sandulescu MS, Tenovici M, Siminel MA, Novac MB
Πηγή: European review for medical and pharmacological sciences [Eur Rev Med Pharmacol Sci] 2023 Feb; Vol. 27 (3), pp. 1069-1076.
Τύπος έκδοσης: Journal Article; Comment
Γλώσσα: English
Στοιχεία περιοδικού: Publisher: Verduci Country of Publication: Italy NLM ID: 9717360 Publication Model: Print Cited Medium: Internet ISSN: 2284-0729 (Electronic) Linking ISSN: 11283602 NLM ISO Abbreviation: Eur Rev Med Pharmacol Sci Subsets: MEDLINE
Imprint Name(s): Original Publication: Rome : Verduci, [1997-
Ιατρικοί όροι (MeSH): Endometritis*/diagnosis , Endometritis*/drug therapy , Endometritis*/pathology , Infertility, Female*/therapy, Fertilization in Vitro/adverse effects ; Anti-Bacterial Agents/therapeutic use ; Pregnancy ; Female ; Humans ; Retrospective Studies ; Chronic Disease ; Hysteroscopy
Περίληψη: Objective: A significant cause of infertility is the inability of the embryo to implant. Endometritis is one of the major causes affecting embryo implantation. The present study addressed the diagnosis and effects of chronic endometritis (CE) treatment on pregnancy rates after in vitro fertilization (IVF).
Patients and Methods: We conducted this retrospective study on 578 infertile couples treated with IVF. In 446 couples, we performed a control hysteroscopy with biopsy before IVF. In addition, we examined the visual aspects of the hysteroscopy and the results of the endometrial biopsies, followed by antibiotic therapy if necessary. Finally, the results of IVF were compared.
Results: Of the 446 cases studied, we diagnosed 192 (43%) with chronic endometritis, either by direct observation or based on the histopathological result. In addition, the cases diagnosed with CE we treated with a combination of antibiotics. The group diagnosed at CE and subsequently treated with antibiotic therapy had a significantly higher pregnancy rate after IVF (43.2%) than the group without treatment (27.3%).
Conclusions: Hysteroscopic examination of the uterine cavity was particularly important for the success of IVF. The initial CE diagnosis and treatment were an advantage for the cases in which we performed the IVF procedures.
Σχόλια: Comment on: Rom J Morphol Embryol. 2018;59(2):435-453.. (PMID: 30173248)
Substance Nomenclature: 0 (Anti-Bacterial Agents)
Entry Date(s): Date Created: 20230222 Date Completed: 20230224 Latest Revision: 20230502
Update Code: 20260130
DOI: 10.26355/eurrev_202302_31203
PMID: 36808354
Βάση Δεδομένων: MEDLINE