Academic Journal
Evaluation of the one-minute ultra-rapid urease test for diagnosing Helicobacter pylori.
| Τίτλος: | Evaluation of the one-minute ultra-rapid urease test for diagnosing Helicobacter pylori. |
|---|---|
| Συγγραφείς: | Misra SP; Department of Gastroenterology, MLN Medical College, Allahabad, India., Misra V, Dwivedi M, Singh PA, Bhargava V, Jaiswal PK |
| Πηγή: | Postgraduate medical journal [Postgrad Med J] 1999 Mar; Vol. 75 (881), pp. 154-6. |
| Τύπος έκδοσης: | Comparative Study; Journal Article |
| Γλώσσα: | English |
| Στοιχεία περιοδικού: | Publisher: Oxford University Press Country of Publication: England NLM ID: 0234135 Publication Model: Print Cited Medium: Print ISSN: 0032-5473 (Print) Linking ISSN: 00325473 NLM ISO Abbreviation: Postgrad Med J Subsets: MEDLINE |
| Imprint Name(s): | Publication: 2023- : Oxford : Oxford University Press Original Publication: London, Blackwell. |
| Ιατρικοί όροι (MeSH): | Helicobacter pylori* , Reagent Strips*, Bacteriological Techniques/*instrumentation , Helicobacter Infections/*diagnosis, Biopsy ; Humans ; Sensitivity and Specificity ; Urease |
| Περίληψη: | To determine the diagnostic accuracy of the one-minute ultra-rapid urease test for diagnosing Helicobacter pylori infection, two biopsies were taken from both the gastric corpus and antrum from 1000 patients undergoing upper gastrointestinal endoscopy. All the biopsies were subjected to the one-minute ultra-rapid urease test before imprint smears were prepared from them. Thereafter, the biopsies were fixed in 10% formalin and histological sections were examined for the presence of H pylori by a pathologist who was not aware of the clinical details or the results of the urease test. The prevalence of H pylori in the gastric antrum and corpus was 86.7% and 53.3%, respectively. The sensitivity, specificity, positive and negative predictive value and the overall diagnostic accuracy of the ultra-rapid urease test to diagnose H pylori infection in the gastric antrum were 92%, 100%, 100%, 66%, and 93%, respectively. The corresponding figures for the gastric corpus were 83%, 100%, 100%, 85%, and 91%, respectively. It is concluded that the one-minute ultra-rapid urease test has a high sensitivity and specificity and may be used as a rapid and cheap method to diagnose H pylori infection. |
| References: | Gut. 1992 Apr;33(4):429-31. (PMID: 1582581) Gastroenterol Clin North Am. 1993 Mar;22(1):105-15. (PMID: 8449560) J Gastroenterol Hepatol. 1992 Nov-Dec;7(6):569-71. (PMID: 1486185) Diagn Cytopathol. 1998 May;18(5):330-2. (PMID: 9582566) Gastrointest Endosc. 1997 Dec;46(6):503-6. (PMID: 9434216) J Clin Microbiol. 1991 Apr;29(4):672-5. (PMID: 1890167) Gut. 1991 May;32(5):467-9. (PMID: 2040465) J Clin Pathol. 1989 Aug;42(8):834-9. (PMID: 2768523) Am J Gastroenterol. 1992 Jan;87(1):20-3. (PMID: 1728119) Am J Gastroenterol. 1997 Sep;92(9):1487-91. (PMID: 9317069) Acta Cytol. 1997 Jul-Aug;41(4):1144-6. (PMID: 9250312) Gastrointest Endosc. 1996 Nov;44(5):523-6. (PMID: 8934155) J Gastroenterol Hepatol. 1994 Sep-Oct;9(5):512-3. (PMID: 7530062) Gastrointest Endosc. 1994 May-Jun;40(3):342-5. (PMID: 7794303) Postgrad Med J. 1993 Apr;69(810):291-5. (PMID: 8321793) |
| Substance Nomenclature: | 0 (Reagent Strips) EC 3.5.1.5 (Urease) |
| Entry Date(s): | Date Created: 19990817 Date Completed: 19990830 Latest Revision: 20190501 |
| Update Code: | 20260130 |
| PubMed Central ID: | PMC1741168 |
| DOI: | 10.1136/pgmj.75.881.154 |
| PMID: | 10448493 |
| Βάση Δεδομένων: | MEDLINE |
καταχωρήστε σχόλιο πρώτοι!