Academic Journal

The Effect of Chronic Swimming Exercise and Vitamin E Supplementation on Bone Element Metabolism in Epileptic Rats.

Λεπτομέρειες βιβλιογραφικής εγγραφής
Τίτλος: The Effect of Chronic Swimming Exercise and Vitamin E Supplementation on Bone Element Metabolism in Epileptic Rats.
Συγγραφείς: Baltacı, Saltuk Buğra1 (AUTHOR), Tutkun, Erkut2 (AUTHOR), Ayyıldız, Mustafa3 (AUTHOR), Ağar, Erdal3 (AUTHOR), Arslan, Gökhan3 (AUTHOR), Moğulkoç, Rasim4 (AUTHOR), Baltacı, Abdülkerim Kasım4 (AUTHOR) baltaci61@yahoo.com
Πηγή: Archives of Neuropsychiatry / Nöropsikiyatri Arşivi. Jun2024, Vol. 61 Issue 2, p113-118. 6p.
Θεματικοί όροι: *Zinc analysis, *Copper analysis, *Analysis of bones, *Iron analysis, *Lead analysis, *Chromium analysis, *Treatment of epilepsy, *Exercise physiology, *Iron in the body, *Manganese, *Gastric intubation, *Magnesium, *Chemical elements, *Exercise therapy, *Descriptive statistics, *Rats, *Calcium, *Swimming, *Vitamin E, *Animal experimentation, *Penicillin
Περίληψη: Introduction: This study aimed to investigate the effects of chronic swimming exercise and vitamin E administration on elemental levels in the bone tissue of epileptic rats. Methods: Forty-eight rats were divided into six groups: Control, Swimming, Swimming + vitamin E, Swimming + Epilepsy, Swimming + Epilepsy + vitamin E, and Epilepsy. Vitamin E was administered to the animals chronically by gavage at a dose of 500 mg/kg every other day for 3 months. Epileptiform activity was induced with penicillin in animals 24 hours after the last vitamin E intake. The exercise program consisted of daily 30-minute swimming sessions. At the end of the treatment period, the levels of calcium, chromium, copper, iron, magnesium, manganese, lead, and zinc (µg/gram tissue) in bone tissue samples were measured using an atomic emission device. Results: The results showed that all epileptic groups had significantly lower bone chromium levels compared to the control groups (p<0.05). The epileptic, and epileptic swimming groups had the lowest levels of bone calcium, magnesium, and zinc (p<0.05). Vitamin E administration resulted in a significant increase in bone calcium, magnesium, and zinc levels in the epileptic swimming group with vitamin E compared to the epileptic and epileptic swimming groups. (p<0.05). Conclusion: The findings of the study show that the administration of vitamin E improves calcium, magnesium, and zinc metabolism in the deteriorated bone tissue of the epileptic rat model. [ABSTRACT FROM AUTHOR]
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