Ultrasound-assisted 1,2,4-triazole Schiff bases: synthesis, characterization, docking, and dual inhibition of urease and α-glucosidase.

Συγγραφείς: Gültekin E; Science-Technology Research and Application Center, Artvin Coruh University, Artvin, Türkiye.

Πηγή: Future medicinal chemistry [Future Med Chem] 2026 Jul; Vol. 18 (13), pp. 1701-1711. Date of Electronic Publication: 2026 May 19.

Τύπος έκδοσης: Journal Article

Στοιχεία περιοδικού: Publisher: Taylor & Francis Country of Publication: England NLM ID: 101511162 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1756-8927 (Electronic) Linking ISSN: 17568919 NLM ISO Abbreviation: Future Med Chem Subsets: MEDLINE

Ιατρικοί όροι (MeSH): Triazoles*/chemistry , Triazoles*/pharmacology , Triazoles*/chemical synthesis , Urease*/antagonists & inhibitors , Urease*/metabolism , alpha-Glucosidases*/metabolism , Glycoside Hydrolase Inhibitors*/chemistry , Glycoside Hydrolase Inhibitors*/chemical synthesis , Glycoside Hydrolase Inhibitors*/pharmacology , Enzyme Inhibitors*/chemical synthesis , Enzyme Inhibitors*/chemistry , Enzyme Inhibitors*/pharmacology , Ultrasonic Waves*, Schiff Bases/chemistry ; Schiff Bases/pharmacology ; Schiff Bases/chemical synthesis ; Molecular Docking Simulation ; Structure-Activity Relationship ; Molecular Structure

Engineering Escherichia coli for Urease-Driven Synthesis of Metal Oxide Nanomaterials.

Συγγραφείς: Wu ZY; The U.S. Department of Energy Joint Genome Institute, Lawrence Berkeley National Laboratory, Berkeley, California 94720, United States.; Environmental Genomics and Systems Biology Division, Lawrence Berkeley National Laboratory, Berkeley, California 94720, United States., Lin AYW; The Molecular Foundry, Lawrence Berkeley National Laboratory, Berkeley, California 94720, United States., Müller IE; The U.S. Department of Energy Joint Genome Institute, Lawrence Berkeley National Laboratory, Berkeley, California 94720, United States., Zhao Z; The U.S. Department of Energy Joint Genome Institute, Lawrence Berkeley National Laboratory, Berkeley, California 94720, United States., Mouncey NJ; The U.S. Department of Energy Joint Genome Institute, Lawrence Berkeley National Laboratory, Berkeley, California 94720, United States.; Environmental Genomics and Systems Biology Division, Lawrence Berkeley National Laboratory, Berkeley, California 94720, United States., Ercius P; The Molecular Foundry, Lawrence Berkeley National Laboratory, Berkeley, California 94720, United States., Yoshikuni Y; The U.S. Department of Energy Joint Genome Institute, Lawrence Berkeley National Laboratory, Berkeley, California 94720, United States.; Environmental Genomics and Systems Biology Division, Lawrence Berkeley National Laboratory, Berkeley, California 94720, United States.; Biological Systems and Engineering Division, Lawrence Berkeley National Laboratory, Berkeley, California 94720, United States.; U.S. Department of Energy Center for Bioenergy and Bioproducts Innovation (CABBI), Lawrence Berkeley National Laboratory, Berkeley, California 94720, United States.; Energy and Biosciences Institute, University of California, Berkeley, Berkeley, California 94720, United States.; Global Institution for Collaborative Research and Education, Hokkaido University, Hokkaido 060-8589, Japan.

Πηγή: ACS synthetic biology [ACS Synth Biol] 2026 Jun 19; Vol. 15 (6), pp. 2264-2273. Date of Electronic Publication: 2026 Jun 08.

Τύπος έκδοσης: Journal Article

Στοιχεία περιοδικού: Publisher: American Chemical Society Country of Publication: United States NLM ID: 101575075 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2161-5063 (Electronic) Linking ISSN: 21615063 NLM ISO Abbreviation: ACS Synth Biol Subsets: MEDLINE

Ιατρικοί όροι (MeSH): Escherichia coli*/genetics , Escherichia coli*/metabolism , Urease*/metabolism , Urease*/genetics , Metal Nanoparticles*/chemistry , Nanostructures*/chemistry, Titanium/chemistry ; Titanium/metabolism ; Sporosarcina/genetics ; Sporosarcina/enzymology ; Ferric Compounds/chemistry ; Ferric Compounds/metabolism ; Calcium Carbonate/metabolism ; Calcium Carbonate/chemistry ; Calcium Phosphates/metabolism ; Calcium Phosphates/chemistry ; Oxides/chemistry ; Oxides/metabolism

SCR Organism: Sporosarcina pasteurii

Mechanistic insights into Helicobacter pylori urease inhibition by poplar propolis ethanol extract.

Συγγραφείς: Yuan J; College of Agriculture and Biology, Liaocheng University, Liaocheng, People's Republic of China; Institut for Advanced Studies, Universiti Malaya, Kuala Lumpur, Malaysia., Li T; College of Agriculture and Biology, Liaocheng University, Liaocheng, People's Republic of China., Gao S; College of Agriculture and Biology, Liaocheng University, Liaocheng, People's Republic of China., Tang Y; College of Agriculture and Biology, Liaocheng University, Liaocheng, People's Republic of China., Ma S; College of Agriculture and Biology, Liaocheng University, Liaocheng, People's Republic of China., Lee HY; Tropical Infectious Diseases Research and Education Centre, Universiti Malaya, Kuala Lumpur, Malaysia. Electronic address: leehaiyen@um.edu.my., Chin KL; Institut for Advanced Studies, Universiti Malaya, Kuala Lumpur, Malaysia; Department of Medical Microbiology, Universiti Malaya, Kuala Lumpur, Malaysia. Electronic address: chinkimling@um.edu.my., Xuan H; College of Agriculture and Biology, Liaocheng University, Liaocheng, People's Republic of China. Electronic address: xuanhongzhuan@lcu.edu.cn.

Πηγή: Journal of ethnopharmacology [J Ethnopharmacol] 2026 Jun 28; Vol. 365, pp. 121596. Date of Electronic Publication: 2026 Mar 28.

Τύπος έκδοσης: Journal Article

Στοιχεία περιοδικού: Publisher: Elsevier Sequoia Country of Publication: Ireland NLM ID: 7903310 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1872-7573 (Electronic) Linking ISSN: 03788741 NLM ISO Abbreviation: J Ethnopharmacol Subsets: MEDLINE

Ιατρικοί όροι (MeSH): Urease*/antagonists & inhibitors , Urease*/metabolism , Urease*/genetics , Propolis*/pharmacology , Propolis*/chemistry , Helicobacter pylori*/drug effects , Helicobacter pylori*/enzymology , Helicobacter pylori*/growth & development , Plant Extracts*/pharmacology , Plant Extracts*/chemistry , Anti-Bacterial Agents*/pharmacology , Anti-Bacterial Agents*/isolation & purification , Anti-Bacterial Agents*/chemistry , Populus*/chemistry , Enzyme Inhibitors*/pharmacology, Ethanol/chemistry ; Molecular Docking Simulation

Synthesis, crystal structures and urease inhibition of Ni(II) complexes constructed from Schiff bases with 2,2'-bipyridine as co-ligands.

Συγγραφείς: Liu WY; Department of Pharmacy, Henan Provincial People's Hospital; People's Hospital of Zhengzhou University; People's Hospital of Henan University, Zhengzhou, Henan, 450003, China. SJun@zzu.edu.cn., Li HL; Department of Pharmacy, Kangda College of Nanjing Medical University, Lianyungang, 222000, China., Jia JS; Department of Pharmacy, Henan Provincial People's Hospital; People's Hospital of Zhengzhou University; People's Hospital of Henan University, Zhengzhou, Henan, 450003, China. SJun@zzu.edu.cn., Zhao WM; Department of Pharmacy, Henan Provincial People's Hospital; People's Hospital of Zhengzhou University; People's Hospital of Henan University, Zhengzhou, Henan, 450003, China. SJun@zzu.edu.cn., Sun J; Department of Pharmacy, Henan Provincial People's Hospital; People's Hospital of Zhengzhou University; People's Hospital of Henan University, Zhengzhou, Henan, 450003, China. SJun@zzu.edu.cn.

Πηγή: Dalton transactions (Cambridge, England : 2003) [Dalton Trans] 2026 Jun 02; Vol. 55 (21), pp. 8258-8271. Date of Electronic Publication: 2026 Jun 02.

Τύπος έκδοσης: Journal Article

Στοιχεία περιοδικού: Publisher: Royal Society of Chemistry Country of Publication: England NLM ID: 101176026 Publication Model: Electronic Cited Medium: Internet ISSN: 1477-9234 (Electronic) Linking ISSN: 14779226 NLM ISO Abbreviation: Dalton Trans Subsets: MEDLINE

Ιατρικοί όροι (MeSH): Urease*/antagonists & inhibitors , Urease*/metabolism , 2,2'-Dipyridyl*/chemistry , Coordination Complexes*/chemistry , Coordination Complexes*/chemical synthesis , Coordination Complexes*/pharmacology , Nickel*/chemistry , Nickel*/pharmacology , Enzyme Inhibitors*/chemistry , Enzyme Inhibitors*/chemical synthesis , Enzyme Inhibitors*/pharmacology, Schiff Bases/chemistry ; Schiff Bases/pharmacology ; Ligands ; Crystallography, X-Ray ; Molecular Structure ; Models, Molecular ; Molecular Docking Simulation

Synthesis and Evaluation of Isatin Analogs as Potential Urease and Tyrosinase Inhibitors: An Approach of Molecular Docking.

Συγγραφείς: Ma G; School of Chemistry & Materials Engineering, Xinxiang University, Xinxiang, Henan, China., Li Y; School of Pharmacy, Xinxiang University, Xinxiang, Henan, China., Xu S; School of Pharmacy, Xinxiang University, Xinxiang, Henan, China., Javid MT; Department of Chemistry, University of Layyah, Layyah, Punjab, Pakistan., Ahmed N; Department of Chemistry, PMAS-Aid Agriculture University, Rawalpindi, Pakistan., Farooq U; Miami College of Henan University, Kaifeng, Henan, China.

Πηγή: Chemistry & biodiversity [Chem Biodivers] 2026 May; Vol. 23 (5), pp. e71285.

Τύπος έκδοσης: Journal Article

Στοιχεία περιοδικού: Publisher: Verlag Helvetica Chimica Acta Country of Publication: Switzerland NLM ID: 101197449 Publication Model: Print Cited Medium: Internet ISSN: 1612-1880 (Electronic) Linking ISSN: 16121872 NLM ISO Abbreviation: Chem Biodivers Subsets: MEDLINE

Ιατρικοί όροι (MeSH): Urease*/antagonists & inhibitors , Urease*/metabolism , Isatin*/chemical synthesis , Isatin*/chemistry , Isatin*/pharmacology , Isatin*/analogs & derivatives , Monophenol Monooxygenase*/antagonists & inhibitors , Monophenol Monooxygenase*/metabolism , Enzyme Inhibitors*/chemical synthesis , Enzyme Inhibitors*/chemistry , Enzyme Inhibitors*/pharmacology , Molecular Docking Simulation*, Schiff Bases/chemistry ; Schiff Bases/chemical synthesis ; Schiff Bases/pharmacology ; Structure-Activity Relationship ; Molecular Structure ; Dose-Response Relationship, Drug

Design, synthesis and biological profiling of bis-thiazole linked Schiff bases as effective enzyme inhibitors for targeting urease and thymidine phosphorylase proteins.

Συγγραφείς: Khan Y; Department of Chemistry, COMSATS University Islamabad, Islamabad, 45550, Pakistan. yousaf7n@gmail.com., Sarfraz H; Department of Chemistry, Quaid-I-Azam University Islamabad, Islamabad, 45320, Pakistan., Naseem M; Department of Zoology, University of Balochistan, Quetta, Pakistan., Adnan R; Department of Computer Science, COMSATS University Islamabad, Islamabad, 45550, Pakistan., Naqvi SF; Department of Zoology, Quaid-I-Azam University Islamabad, Islamabad, 45320, Pakistan., Khan A; Department of Zoology, Quaid-I-Azam University Islamabad, Islamabad, 45320, Pakistan., Gulshan U; Department of Chemistry, COMSATS University Islamabad, Islamabad, 45550, Pakistan., Aminullah S; Department of Chemistry, COMSATS University Islamabad, Islamabad, 45550, Pakistan.

Πηγή: Naunyn-Schmiedeberg's archives of pharmacology [Naunyn Schmiedebergs Arch Pharmacol] 2026 Mar; Vol. 399 (6), pp. 8883-8906. Date of Electronic Publication: 2026 Jan 15.

Τύπος έκδοσης: Journal Article

Στοιχεία περιοδικού: Publisher: Springer Verlag Country of Publication: Germany NLM ID: 0326264 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-1912 (Electronic) Linking ISSN: 00281298 NLM ISO Abbreviation: Naunyn Schmiedebergs Arch Pharmacol Subsets: MEDLINE

Ιατρικοί όροι (MeSH): Urease*/antagonists & inhibitors , Urease*/metabolism , Thymidine Phosphorylase*/antagonists & inhibitors , Thymidine Phosphorylase*/metabolism , Thiazoles*/pharmacology , Thiazoles*/chemistry , Thiazoles*/chemical synthesis , Enzyme Inhibitors*/pharmacology , Enzyme Inhibitors*/chemical synthesis , Enzyme Inhibitors*/chemistry , Drug Design*, Schiff Bases/pharmacology ; Schiff Bases/chemical synthesis ; Schiff Bases/chemistry ; Structure-Activity Relationship ; Molecular Docking Simulation ; Humans

Green-synthesized silver nanoparticles optimized by Taguchi method inhibit urease activity in antibiotic-resistant helicobacter pylori.

Συγγραφείς: Ghanbari R; Department of Medicinal Chemistry, School of Pharmacy, Zanjan University of Medical Sciences, Zanjan, Iran., Yazdinezhad A; Department of Pharmacognosy and Traditional Pharmacy, School of Pharmacy, Zanjan University of Medical Sciences, Zanjan, Iran., Danafar H; Department of Medicinal Chemistry, School of Pharmacy, Zanjan University of Medical Sciences, Zanjan, Iran., Asadi S; Department of Medicinal Chemistry, School of Pharmacy, Zanjan University of Medical Sciences, Zanjan, Iran., Salehabadi H; Department of Medicinal Chemistry, School of Pharmacy, Zanjan University of Medical Sciences, Zanjan, Iran. hsalehabadi@zums.ac.ir.

Πηγή: Scientific reports [Sci Rep] 2026 May 18; Vol. 16 (1). Date of Electronic Publication: 2026 May 18.

Τύπος έκδοσης: Journal Article

Στοιχεία περιοδικού: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE

Ιατρικοί όροι (MeSH): Urease*/antagonists & inhibitors , Urease*/metabolism , Metal Nanoparticles*/chemistry , Helicobacter pylori*/drug effects , Helicobacter pylori*/enzymology , Silver*/chemistry , Silver*/pharmacology , Anti-Bacterial Agents*/pharmacology , Anti-Bacterial Agents*/chemistry , Drug Resistance, Bacterial*/drug effects , Enzyme Inhibitors*/pharmacology , Enzyme Inhibitors*/chemistry, Green Chemistry Technology/methods ; Plant Extracts/chemistry ; Citrus/chemistry ; Spectroscopy, Fourier Transform Infrared ; Particle Size

First report of microbially induced phosphate precipitation (MIPP) for sand solidification at low temperatures via acid urease producing bacteria.

Συγγραφείς: Kato T; Technical Research and Development Institute, Kumagai Gumi Co., Ltd, Tsukuba, Japan. tatsuhiro.kato@ku.kumagaigumi.co.jp.; Graduate School of Engineering, Hokkaido University, Sapporo, Japan. tatsuhiro.kato@ku.kumagaigumi.co.jp., Kawasaki S; Faculty of Engineering, Hokkaido University, Sapporo, Japan.

Πηγή: World journal of microbiology & biotechnology [World J Microbiol Biotechnol] 2026 Apr 29; Vol. 42 (5). Date of Electronic Publication: 2026 Apr 29.

Τύπος έκδοσης: Journal Article

Στοιχεία περιοδικού: Publisher: Springer Country of Publication: Germany NLM ID: 9012472 Publication Model: Electronic Cited Medium: Internet ISSN: 1573-0972 (Electronic) Linking ISSN: 09593993 NLM ISO Abbreviation: World J Microbiol Biotechnol Subsets: MEDLINE

Ιατρικοί όροι (MeSH): Urease*/metabolism , Phosphates*/chemistry , Phosphates*/metabolism , Pseudomonas*/enzymology , Pseudomonas*/metabolism , Sand*/chemistry, Calcium Phosphates/chemistry ; Calcium Phosphates/metabolism ; Ammonia/metabolism ; Urea/metabolism ; Soil/chemistry ; Chemical Precipitation ; Cold Temperature ; Biological Products ; Minerals

Comprehensive Review and Outlook of the Synthetic Urease Inhibitors for Agricultural Applications.

Συγγραφείς: Song X; CAS Key Laboratory of Forest Ecology and Silviculture, Institute of Applied Ecology, Chinese Academy of Science, Shenyang 110016, China., Zhang W; CAS Key Laboratory of Forest Ecology and Silviculture, Institute of Applied Ecology, Chinese Academy of Science, Shenyang 110016, China.; School of Life Science and Biopharmaceutics, Shenyang Pharmaceutical University, Shenyang 110016, Liaoning, PR China., Bai Y; CAS Key Laboratory of Forest Ecology and Silviculture, Institute of Applied Ecology, Chinese Academy of Science, Shenyang 110016, China., Zhang L; CAS Key Laboratory of Forest Ecology and Silviculture, Institute of Applied Ecology, Chinese Academy of Science, Shenyang 110016, China., Hu J; CAS Key Laboratory of Forest Ecology and Silviculture, Institute of Applied Ecology, Chinese Academy of Science, Shenyang 110016, China., Wu Z; CAS Key Laboratory of Forest Ecology and Silviculture, Institute of Applied Ecology, Chinese Academy of Science, Shenyang 110016, China., Pan H; CAS Key Laboratory of Forest Ecology and Silviculture, Institute of Applied Ecology, Chinese Academy of Science, Shenyang 110016, China.

Πηγή: Journal of agricultural and food chemistry [J Agric Food Chem] 2026 Apr 01; Vol. 74 (12), pp. 9933-9957. Date of Electronic Publication: 2026 Mar 18.

Τύπος έκδοσης: Journal Article; Review

Στοιχεία περιοδικού: Publisher: American Chemical Society Country of Publication: United States NLM ID: 0374755 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-5118 (Electronic) Linking ISSN: 00218561 NLM ISO Abbreviation: J Agric Food Chem Subsets: MEDLINE

Ιατρικοί όροι (MeSH): Urease*/antagonists & inhibitors , Urease*/chemistry , Urease*/metabolism , Enzyme Inhibitors*/chemistry , Enzyme Inhibitors*/chemical synthesis , Enzyme Inhibitors*/pharmacology, Plant Proteins/chemistry ; Plant Proteins/antagonists & inhibitors ; Plant Proteins/metabolism ; Structure-Activity Relationship ; Molecular Docking Simulation ; Agriculture

Urease-driven nanomotors loaded with sorafenib for magnetically-guided accumulation and deep tissue penetration towards hepatocellular carcinoma therapy via ferroptosis induction.

Συγγραφείς: Hua C; Department of General Surgery, The Second Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang, 150086, China., Lu Z; Department of General Surgery, The Second Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang, 150086, China., Cui W; Postgraduate Department, The Second Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang, 150086, China., Ren W; The second Department of General Surgery, Second Hospital of Harbin, Harbin, Heilongjiang, 150056, China., Xu Y; Department of Hepatopancreatobiliary Surgery, Second Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang, 150086, China., Li J; Department of General Surgery, The Second Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang, 150086, China., Zhao X; Department of General Surgery, The Second Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang, 150086, China., Zhao S; Department of General Surgery, The Second Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang, 150086, China., Kang P; Department of General Surgery, The Second Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang, 150086, China. kang_pengcheng@126.com., Cui Y; Department of General Surgery, The Second Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang, 150086, China. yfcui7@163.com.

Πηγή: Mikrochimica acta [Mikrochim Acta] 2026 Jan 26; Vol. 193 (2), pp. 110. Date of Electronic Publication: 2026 Jan 26.

Τύπος έκδοσης: Journal Article

Στοιχεία περιοδικού: Publisher: Springer-Verlag Country of Publication: Austria NLM ID: 7808782 Publication Model: Electronic Cited Medium: Internet ISSN: 1436-5073 (Electronic) Linking ISSN: 00263672 NLM ISO Abbreviation: Mikrochim Acta Subsets: MEDLINE

Ιατρικοί όροι (MeSH): Sorafenib*/pharmacology , Sorafenib*/chemistry , Sorafenib*/therapeutic use , Sorafenib*/metabolism , Liver Neoplasms*/drug therapy , Liver Neoplasms*/pathology , Liver Neoplasms*/metabolism , Carcinoma, Hepatocellular*/drug therapy , Carcinoma, Hepatocellular*/pathology , Carcinoma, Hepatocellular*/metabolism , Antineoplastic Agents*/pharmacology , Antineoplastic Agents*/chemistry , Antineoplastic Agents*/therapeutic use , Urease*/metabolism , Urease*/chemistry , Ferroptosis*/drug effects, Silicon Dioxide/chemistry ; Drug Carriers/chemistry ; Magnetite Nanoparticles/chemistry ; Humans ; Animals ; Mice ; Drug Liberation ; Cell Line, Tumor

Synthesis of thiosemicarbazone derivatives of thiophene-2-carboxylic acid as potent urease inhibitors: in vitro evaluation, molecular docking, and density functional theory analysis.

Συγγραφείς: Khan W; Department of Chemistry, Abdul Wali Khan University, Mardan, Pakistan., Laiba; Department of Chemistry, Abdul Wali Khan University, Mardan, Pakistan., Ahmad I; Programa de Pós-Graduação em Bioquímica e Bioprospecção, Universidade Federal de Pelotas, Pelotas, Brazil., Elhenawy AA; Chemistry Department, Faculty of Science, Al-Azhar University, Cairo, Egypt., Shah SAA; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Universiti Teknologi MARA Puncak Alam Campus, Bandar Puncak Alam, Malaysia.; Atta-ur-Rahman Institute for Natural Product Discovery (AuRIns), Universiti Teknologi MARA Cawangan Selangor Kampus Puncak Alam, Bandar Puncak Alam, Malaysia., Alanazi AS; Department of Pharmaceutical Sciences, College of Pharmacy, Princess Nourah bint Abdulrahman University, Riyadh, Saudi Arabia., Shakoor A; Department of Chemistry, Abdul Wali Khan University, Mardan, Pakistan., Alam A; Department of Chemistry, Rawalpindi Women University, Rawalpindi, Pakistan., Khan M; Department of Chemistry, Abdul Wali Khan University, Mardan, Pakistan., Alanazi MM; Department of Pharmaceutical Chemistry, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia.

Πηγή: Future medicinal chemistry [Future Med Chem] 2026 Aug; Vol. 18 (16), pp. 2147-2159. Date of Electronic Publication: 2026 Jul 13.

Τύπος έκδοσης: Journal Article

Στοιχεία περιοδικού: Publisher: Taylor & Francis Country of Publication: England NLM ID: 101511162 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1756-8927 (Electronic) Linking ISSN: 17568919 NLM ISO Abbreviation: Future Med Chem Subsets: MEDLINE

Ιατρικοί όροι (MeSH): Urease*/antagonists & inhibitors , Urease*/metabolism , Enzyme Inhibitors*/chemical synthesis , Enzyme Inhibitors*/chemistry , Enzyme Inhibitors*/pharmacology , Thiosemicarbazones*/chemistry , Thiosemicarbazones*/chemical synthesis , Thiosemicarbazones*/pharmacology , Thiophenes*/chemistry , Thiophenes*/pharmacology , Thiophenes*/chemical synthesis , Density Functional Theory*, Molecular Docking Simulation ; Structure-Activity Relationship ; Molecular Structure ; Molecular Dynamics Simulation ; Carboxylic Acids

Inhibition of urease by urea/thiourea-derived heterocycles: IC50 profiling and structure-activity relationship.

Συγγραφείς: Bağ A; Institute of Science, Kafkas University, 36100, Kars, Turkey., Uluçay O; Department of Bioengineering, Faculty of Engineering and Architecture, Kafkas University, 36100, Kars, Turkey. Electronic address: orhanulucay@gmail.com.

Πηγή: Biochimie [Biochimie] 2026 Jun; Vol. 245, pp. 160-167. Date of Electronic Publication: 2026 Mar 23.

Τύπος έκδοσης: Journal Article

Στοιχεία περιοδικού: Publisher: Editions Scientifiques Elsevier Country of Publication: France NLM ID: 1264604 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1638-6183 (Electronic) Linking ISSN: 03009084 NLM ISO Abbreviation: Biochimie Subsets: MEDLINE

Ιατρικοί όροι (MeSH): Urease*/antagonists & inhibitors , Urease*/chemistry , Thiourea*/chemistry , Enzyme Inhibitors*/chemistry , Enzyme Inhibitors*/pharmacology , Urea*/chemistry , Heterocyclic Compounds*/chemistry , Heterocyclic Compounds*/pharmacology, Canavalia/enzymology ; Structure-Activity Relationship ; Inhibitory Concentration 50

Structure-activity studies reveal efficient inactivation of urease by Ebsulfur-based compounds.

Συγγραφείς: Mazzei L; Laboratory of Bioinorganic Chemistry, Department of Pharmacy and Biotechnology (FaBiT), University of Bologna, I-40138 Bologna, Italy. Electronic address: luca.mazzei2@unibo.it., Paul A; Laboratory of Bioinorganic Chemistry, Department of Pharmacy and Biotechnology (FaBiT), University of Bologna, I-40138 Bologna, Italy. Electronic address: arundhati.paul2@unibo.it., Cianci M; Department of Agricultural, Food and Environmental Sciences, Polytechnic University of Marche, I-60131 Ancona, Italy. Electronic address: m.cianci@staff.univpm.it., Pizzi A; Department of Chemistry, Materials, and Chemical Engineering 'Giulio Natta', Politecnico di Milano, I-20131 Milano, Italy. Electronic address: andrea.pizzi@polimi.it., Resnati G; Department of Chemistry, Materials, and Chemical Engineering 'Giulio Natta', Politecnico di Milano, I-20131 Milano, Italy. Electronic address: giuseppe.resnati@polimi.it., Ciurli S; Laboratory of Bioinorganic Chemistry, Department of Pharmacy and Biotechnology (FaBiT), University of Bologna, I-40138 Bologna, Italy. Electronic address: stefano.ciurli@unibo.it.

Πηγή: Journal of inorganic biochemistry [J Inorg Biochem] 2026 Jun; Vol. 279, pp. 113272. Date of Electronic Publication: 2026 Feb 21.

Τύπος έκδοσης: Journal Article

Στοιχεία περιοδικού: Publisher: Elsevier Country of Publication: United States NLM ID: 7905788 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-3344 (Electronic) Linking ISSN: 01620134 NLM ISO Abbreviation: J Inorg Biochem Subsets: MEDLINE

Ιατρικοί όροι (MeSH): Urease*/antagonists & inhibitors , Urease*/chemistry , Sporosarcina*/enzymology , Azoles*/chemistry , Azoles*/pharmacology , Organoselenium Compounds*/chemistry , Organoselenium Compounds*/pharmacology , Canavalia*/enzymology , Enzyme Inhibitors*/chemistry , Enzyme Inhibitors*/pharmacology, Isoindoles ; Structure-Activity Relationship ; Crystallography, X-Ray

SCR Organism: Sporosarcina pasteurii

Study on the irradiation control of urease activity and its solidification of red clay to enhance radon reduction.

Συγγραφείς: Tang Y; School of Resources, Environmental and Safety Engineering, University of South China, Hengyang 421001, China., Liang R; School of Resources, Environmental and Safety Engineering, University of South China, Hengyang 421001, China., Wei J; School of Resources, Environmental and Safety Engineering, University of South China, Hengyang 421001, China., Sun Y; School of Resources, Environmental and Safety Engineering, University of South China, Hengyang 421001, China., Peng W; School of Resources, Environmental and Safety Engineering, University of South China, Hengyang 421001, China., Li F; School of Resources, Environmental and Safety Engineering, University of South China, Hengyang 421001, China., Zhang C; School of Resources, Environmental and Safety Engineering, University of South China, Hengyang 421001, China., Hong C; School of Resources, Environmental and Safety Engineering, University of South China, Hengyang 421001, China. Electronic address: hongchangshou@163.com.

Πηγή: Journal of environmental radioactivity [J Environ Radioact] 2026 Feb; Vol. 293, pp. 107879. Date of Electronic Publication: 2026 Jan 06.

Τύπος έκδοσης: Journal Article

Στοιχεία περιοδικού: Publisher: Elsevier Applied Science Publishers Country of Publication: England NLM ID: 8508119 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-1700 (Electronic) Linking ISSN: 0265931X NLM ISO Abbreviation: J Environ Radioact Subsets: MEDLINE

Ιατρικοί όροι (MeSH): Radon*/analysis , Radon*/chemistry , Urease*/metabolism , Urease*/chemistry , Soil Pollutants, Radioactive*/analysis, Clay/chemistry ; Glycine max/enzymology ; Calcium Carbonate/chemistry

Macromolecular scaffolds with nitrogen-sulfur motifs: Dual α-glucosidase and urease inhibition with molecular docking and mechanistic evaluation.

Συγγραφείς: Khan S; Department of Chemistry, Abbottabad University of Science and Technology, Abbottabad, 22500, Pakistan. Electronic address: shoaibkhanswati@gmail.com., Iqbal T; Department of Chemistry, Abbottabad University of Science and Technology, Abbottabad, 22500, Pakistan., Abass KS; Department of Physiology, Biochemistry, and Pharmacology, College of Veterinary Medicine, University of Kirkuk, Kirkuk, 36001, Iraq., Alzahrani E; Department of Chemistry, College of Science, Taif University, PO Box 11099, Taif, 21944, Saudi Arabia., Gomha SM; Department of Chemistry, Faculty of Science, Islamic University of Madinah, Madinah, 42351, Saudi Arabia., Zaki MEA; Department of Chemistry, Faculty of Science, Imam Mohammad Ibn Saud Islamic University (IMSIU), Riyadh, 11623, Saudi Arabia., Alshehri FF; Department of Medical Laboratories, College of Applied Medical Sciences, Ad Dawadimi, 17464, Shaqra University, Saudi Arabia., Al Shehri ZS; College of Applied Medical Sciences, Shaqra University, Aldawadmi, Saudi Arabia., Kashtoh H; Department of Biotechnology, Yeungnam University, Gyeongsan, 38541, Gyeongbuk, Republic of Korea. Electronic address: hamdy_kashtoh@ynu.ac.kr.

Πηγή: International journal of biological macromolecules [Int J Biol Macromol] 2025 Dec; Vol. 332 (Pt 1), pp. 148369. Date of Electronic Publication: 2025 Oct 19.

Τύπος έκδοσης: Journal Article

Στοιχεία περιοδικού: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 7909578 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-0003 (Electronic) Linking ISSN: 01418130 NLM ISO Abbreviation: Int J Biol Macromol Subsets: MEDLINE

Ιατρικοί όροι (MeSH): Urease*/antagonists & inhibitors , Urease*/chemistry , Urease*/metabolism , alpha-Glucosidases*/chemistry , alpha-Glucosidases*/metabolism , Glycoside Hydrolase Inhibitors*/chemistry , Glycoside Hydrolase Inhibitors*/pharmacology , Glycoside Hydrolase Inhibitors*/chemical synthesis , Nitrogen*/chemistry , Enzyme Inhibitors*/chemistry , Enzyme Inhibitors*/pharmacology , Enzyme Inhibitors*/chemical synthesis , Sulfur*/chemistry , Molecular Docking Simulation*, Indoles/chemistry ; Sulfonamides/chemistry ; Sulfonamides/pharmacology ; Thiadiazoles/chemistry ; Structure-Activity Relationship

Developing a urea biosensor and safe blood cleaning method utilizing a novel high throughput La-doped CeO2 nanosized artificial urease with high biocompatibility and enzyme-like activity.

Συγγραφείς: Ahmad N; Department of Chemistry, College of Science, King Saud University, Riyadh 11451, Saudi Arabia. Electronic address: anaushad@ksu.edu.sa., Bishoyi AK; Marwadi University Research Center, Department of Microbiology, Faculty of Science, Marwadi University, Rajkot, Gujarat, India. Electronic address: ashokkumar.bishoyi@marwadieducation.edu.in., Ballal S; Department of Chemistry and Biochemistry, School of Sciences, JAIN (Deemed to be University), Bengaluru, Karnataka, India. Electronic address: b.suhas@jainuniversity.ac.in., Shankhyan A; Centre for Research Impact & Outcome, Chitkara University Institute of Engineering and Technology, Chitkara University, Rajpura, Punjab 140401, India., Al-Hasnaawei S; College of pharmacy, the Islamic University, Najaf, Iraq; Department of medical analysis, Medical laboratory technique college, the Islamic University of Al Diwaniyah, Al Diwaniyah, Iraq. Electronic address: shakeralhasnawi@iunajaf.edu.iq., Jayabalan K; Department of Chemistry, Sathyabama Institute of Science and Technology, Chennai, Tamil Nadu, India. Electronic address: karthikeyan.chemistry@sathyabama.ac.in., Maharana L; Department of Pharmaceutical Sciences, Siksha 'O' Anusandhan (Deemed to be University), Bhubaneswar, Odisha 751030, India. Electronic address: laxmidharmaharana@soa.ac.in., Lal M; Department of Medicine, National Institute of Medical Sciences, NIMS University Rajasthan, Jaipur, India. Electronic address: Madan.lal1@nimsuniversity.org.

Πηγή: Enzyme and microbial technology [Enzyme Microb Technol] 2025 Dec; Vol. 191, pp. 110736. Date of Electronic Publication: 2025 Aug 15.

Τύπος έκδοσης: Journal Article

Στοιχεία περιοδικού: Publisher: Elsevier Country of Publication: United States NLM ID: 8003761 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-0909 (Electronic) Linking ISSN: 01410229 NLM ISO Abbreviation: Enzyme Microb Technol Subsets: MEDLINE

Ιατρικοί όροι (MeSH): Urease*/metabolism , Urease*/chemistry , Urea*/blood , Urea*/analysis , Biosensing Techniques*/methods , Cerium*/chemistry, Enzymes, Immobilized/metabolism ; Enzymes, Immobilized/chemistry ; Biocompatible Materials/chemistry ; Humans ; Limit of Detection ; Reproducibility of Results

Sodium alginate-based hydrogel combined with MOF-dynamic defect generation strategy: A nanobiocomposite for synergistic enhancement of urease immobilization.

Συγγραφείς: Wang Z; Key Laboratory of Bioactive Materials, Ministry of Education, College of Life Sciences, Nankai University, Tianjin, 300071, China., Wang B; Key Laboratory of Bioactive Materials, Ministry of Education, College of Life Sciences, Nankai University, Tianjin, 300071, China., Yang L; Key Laboratory of Bioactive Materials, Ministry of Education, College of Life Sciences, Nankai University, Tianjin, 300071, China., Guo X; Key Laboratory of Bioactive Materials, Ministry of Education, College of Life Sciences, Nankai University, Tianjin, 300071, China., Liu Z; Key Laboratory of Bioactive Materials, Ministry of Education, College of Life Sciences, Nankai University, Tianjin, 300071, China., Chai Y; General Hospital Tianjin Medical University, Tianjin, 300052, China., Du Y; Key Laboratory of Bioactive Materials, Ministry of Education, College of Life Sciences, Nankai University, Tianjin, 300071, China., Tian Z; Key Laboratory of Bioactive Materials, Ministry of Education, College of Life Sciences, Nankai University, Tianjin, 300071, China., Yang J; Key Laboratory of Bioactive Materials, Ministry of Education, College of Life Sciences, Nankai University, Tianjin, 300071, China., Zhu C; Key Laboratory of Bioactive Materials, Ministry of Education, College of Life Sciences, Nankai University, Tianjin, 300071, China., Cao X; Department of Nephrology, Zhongshan Hospital, Fudan University, Shanghai, 200032, China. Electronic address: cxs15339@126.com., Ou L; Key Laboratory of Bioactive Materials, Ministry of Education, College of Life Sciences, Nankai University, Tianjin, 300071, China. Electronic address: ouyll@nankai.edu.cn.

Πηγή: International journal of biological macromolecules [Int J Biol Macromol] 2026 Jan; Vol. 338 (Pt 1), pp. 149579. Date of Electronic Publication: 2025 Dec 11.

Τύπος έκδοσης: Journal Article

Στοιχεία περιοδικού: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 7909578 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-0003 (Electronic) Linking ISSN: 01418130 NLM ISO Abbreviation: Int J Biol Macromol Subsets: MEDLINE

Ιατρικοί όροι (MeSH): Alginates*/chemistry , Urease*/chemistry , Urease*/metabolism , Enzymes, Immobilized*/chemistry , Enzymes, Immobilized*/metabolism , Hydrogels*/chemistry , Nanocomposites*/chemistry , Metal-Organic Frameworks*/chemistry, Urea/chemistry ; Carrageenan/chemistry ; Biocompatible Materials/chemistry ; Animals ; Humans

Urease-coated polydopamine nanomotors as self-propelled biosensors for non-invasive diagnosis: detection of prostate cancer-associated miR-141 in urine.

Συγγραφείς: Özcan Özseven S; Suleyman Demirel University, Graduate School of Natural and Applied Sciences, Bioengineering, 32260 Isparta, Turkey., Yurdabak Karaca G; Suleyman Demirel University, Isparta Health Services Vocational School, Medical Services and Techniques, 32260 Isparta, Turkey., Öksüz L; Suleyman Demirel University, Faculty of Engineering and Natural Sciences, Department of Physics, 32260 Isparta, Turkey.; PLAZMATEK, Süleyman Demirel University Technokent, No: 105, 32000 Isparta, Turkey., Wang J; Aiiso Yufeng Li Family Department of Chemical and Nano Engineering, University of California San Diego, La Jolla, CA 92093, USA., Uygun Öksüz A; Suleyman Demirel University, Faculty of Engineering and Natural Sciences, Department of Chemistry, 32260 Isparta, Turkey. ayseguluygun@sdu.edu.tr.

Πηγή: Analytical methods : advancing methods and applications [Anal Methods] 2026 Jul 09; Vol. 18 (26), pp. 5523-5535. Date of Electronic Publication: 2026 Jul 09.

Τύπος έκδοσης: Journal Article; Research Support, Non-U.S. Gov't

Στοιχεία περιοδικού: Publisher: RSC Pub Country of Publication: England NLM ID: 101519733 Publication Model: Electronic Cited Medium: Internet ISSN: 1759-9679 (Electronic) Linking ISSN: 17599660 NLM ISO Abbreviation: Anal Methods Subsets: MEDLINE

Ιατρικοί όροι (MeSH): MicroRNAs*/urine , Polymers*/chemistry , Biosensing Techniques*/methods , Prostatic Neoplasms*/urine , Prostatic Neoplasms*/diagnosis , Indoles*/chemistry , Urease*/chemistry , Urease*/metabolism, Biomarkers, Tumor/urine ; Humans ; Male

Unraveling Structural Changes and the Reaction Mechanism in Urease upon Infrared Physical Inactivation.

Συγγραφείς: Shen T; School of Food Science and Engineering, Jiangsu University, 301 Xuefu Road, Zhenjiang, Jiangsu 212013, PR China., Liu Y; School of Food Science and Engineering, Chongqing Technology and Business University, 19 Xuefu Avenue, Nan'an District, Chongqing 400010, PR China., Qu W; School of Food Science and Engineering, Jiangsu University, 301 Xuefu Road, Zhenjiang, Jiangsu 212013, PR China.; Institute of Food Physical Processing, Jiangsu University, 301 Xuefu Road, Zhenjiang, Jiangsu 212013, PR China., Ma H; School of Food Science and Engineering, Jiangsu University, 301 Xuefu Road, Zhenjiang, Jiangsu 212013, PR China.; Institute of Food Physical Processing, Jiangsu University, 301 Xuefu Road, Zhenjiang, Jiangsu 212013, PR China., Jiang Q; Zhenjiang Meibo Infrared Technology Co., Ltd, Dingmao Technology New Town, Zhenjiang, Jiangsu 212013, PR China., Huang Y; Taizhou Agricultural Machinery Technology Promotion Station, Taizhou, Jiangsu 225300, PR China.

Πηγή: Journal of agricultural and food chemistry [J Agric Food Chem] 2026 Jul 22; Vol. 74 (28), pp. 22172-22186. Date of Electronic Publication: 2026 Jul 09.

Τύπος έκδοσης: Journal Article

Στοιχεία περιοδικού: Publisher: American Chemical Society Country of Publication: United States NLM ID: 0374755 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-5118 (Electronic) Linking ISSN: 00218561 NLM ISO Abbreviation: J Agric Food Chem Subsets: MEDLINE

Ιατρικοί όροι (MeSH): Urease*/chemistry , Urease*/metabolism, Protein Conformation/radiation effects ; Kinetics ; Hydrophobic and Hydrophilic Interactions ; Molecular Dynamics Simulation ; Infrared Rays ; Hydrogen Bonding ; Hot Temperature

Urease inhibitors: current advances, therapeutic potentials, and clinical challenges.

Συγγραφείς: Alzoubi OH; Department of Basic Medical Sciences, Faculty of Medicine, Yarmouk University, Irbid, Jordan., Khamees A; Department of Basic Medical Sciences, Faculty of Medicine, Yarmouk University, Irbid, Jordan.; Princess Basma Teaching Hospital, Ministry of Health, Irbid, Jordan., Alzu'bi MB; Department of Basic Medical Sciences, Faculty of Medicine, Yarmouk University, Irbid, Jordan., Freihat SF; Department of Basic Medical Sciences, Faculty of Medicine, Yarmouk University, Irbid, Jordan., Attar A; Department of Basic Medical Sciences, Faculty of Medicine, Yarmouk University, Irbid, Jordan., Abo Sameed H; Department of Basic Medical Sciences, Faculty of Medicine, Yarmouk University, Irbid, Jordan., Alzubi R; Department of Basic Medical Sciences, Faculty of Medicine, Yarmouk University, Irbid, Jordan., Alsamarah AA; Department of Basic Medical Sciences, Faculty of Medicine, Yarmouk University, Irbid, Jordan., Yassin RY; Faculty of Pharmacy, Yarmouk University, Irbid, Jordan., Al-Shami K; Department of Basic Medical Sciences, Faculty of Medicine, Yarmouk University, Irbid, Jordan., Al-Trad B; Department of Biomedical Sciences, College of Veterinary Medicine, King Faisal University, Al-Ahsa, Saudi Arabia., Al-Zoubi RM; Surgical Research Section, Department of Surgery, Hamad Medical Corporation, Doha, Qatar.; Department of Chemistry, Jordan University of Science and Technology, Irbid, Jordan.; Department of Biomedical Sciences, QU-Health, College of Health Sciences, Qatar University, Doha, Qatar., Al Zoubi MS; Department of Basic Medical Sciences, Faculty of Medicine, Yarmouk University, Irbid, Jordan.

Πηγή: Future medicinal chemistry [Future Med Chem] 2026 Jul; Vol. 18 (14), pp. 1907-1923. Date of Electronic Publication: 2026 Jun 15.

Τύπος έκδοσης: Journal Article; Review; Research Support, Non-U.S. Gov't

Στοιχεία περιοδικού: Publisher: Taylor & Francis Country of Publication: England NLM ID: 101511162 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1756-8927 (Electronic) Linking ISSN: 17568919 NLM ISO Abbreviation: Future Med Chem Subsets: MEDLINE

Ιατρικοί όροι (MeSH): Urease*/antagonists & inhibitors , Urease*/metabolism , Enzyme Inhibitors*/chemistry , Enzyme Inhibitors*/pharmacology , Enzyme Inhibitors*/therapeutic use, Helicobacter pylori/drug effects ; Helicobacter pylori/enzymology ; Helicobacter Infections/drug therapy ; Humans ; Animals