Sparse group principal component analysis via double thresholding with application to multi-cellular programs

Συγγραφείς: Xu, Qi, Lei, Jing, Roeder, Kathryn

Θεματικοί όροι: Methodology, Applications, Computation

Σύνδεσμος πρόσβασης: http://arxiv.org/abs/2602.04178

Experience report of Hands-on Training Program E: Exploring multi-cellular mechanics

Συγγραφείς: Asuka Takeda-Sakazume

Πηγή: Biophysics and Physicobiology, Vol 21 (2024)

Θεματικοί όροι: Biology (General), QH301-705.5, Physiology, QP1-981, Physics, QC1-999

Περιγραφή αρχείου: electronic resource

Relation: https://doaj.org/toc/2189-4779

Σύνδεσμος πρόσβασης: https://doaj.org/article/c76128a826b8433c8976512ef42b6967

Shared multicellular injury programs of acute and chronic kidney disease enable mechanistic patient stratification

Συγγραφείς: Fallegger, Robin, Gomez-Ochoa, Sergio A., Boys, Charlotte, Ramirez Flores, Ricardo Omar, Tanevski, Jovan, Pashos, Evanthia, Feliers, Denis, Piper, Mary, Schaub, Jennifer A., Zhou, Zixiang, Mao, Weiguang, Chen, Xi, Sealfon, Rachel S. G., Menon, Rajasree, Nair, Viji, Eddy, Sean, Alakwaa, Fadhl M., Pyle, Laura, Choi, Ye Ji, Bjornstad, Petter, Alpers, Charles E., Bitzer, Markus, Bomback, Andrew S., Caramori, M. Luiza, Demeke, Dawit, Fogo, Agnes B., Herlitz, Leal C., Kiryluk, Krzysztof, Lash, James P., Murugan, Raghavan, O'Toole, John F., Palevsky, Paul M., Parikh, Chirag R., Rosas, Sylvia E., Rosenberg, Avi Z., Sedor, John R., Vazquez, Miguel A., Waikar, Sushrut S., Wilson, F. Perry, Hodgin, Jeffrey B., Barisoni, Laura, Himmelfarb, Jonathan, Jain, Sanjay, Ju, Wenjun, Troyanskaya, Olga G., Kretzler, Matthias, Eadon, Michael T., Saez-Rodriguez, Julio

Συνεισφορές: Medicine, School of Medicine

Πηγή: PMC

Θεματικοί όροι: Acute kidney injury, Chronic kidney disease, Single cell transcriptomics, Multi-cellular programs

Περιγραφή αρχείου: application/pdf

Relation: https://hdl.handle.net/1805/55148

Διαθεσιμότητα: https://hdl.handle.net/1805/55148

A hypothetical Master Development Program for multi-cellular organisms: Ontogeny and phylogeny

Συγγραφείς: Parris, George E. ^∗

Πηγή: In Bioscience Hypotheses 2009 2(1):3-12

Shared multicellular injury programs of acute and chronic kidney disease enable mechanistic patient stratification.

Συγγραφείς: Fallegger R; Heidelberg University, Faculty of Medicine, and Heidelberg University Hospital, Institute for Computational Biomedicine, Heidelberg, Germany., Gomez-Ochoa SA; Heidelberg University Hospital, Department of General Internal Medicine and Psychosomatics, Heidelberg, Germany., Boys C; Heidelberg University, Faculty of Medicine, and Heidelberg University Hospital, Institute for Computational Biomedicine, Heidelberg, Germany., Flores ROR; European Molecular Biology Laboratory, European Bioinformatics Institute (EMBL-EBI), Hinxton, Cambridgeshire, U.K., Tanevski J; Heidelberg University, Faculty of Medicine, and Heidelberg University Hospital, Institute for Computational Biomedicine, Heidelberg, Germany., Pashos E; Internal Medicine Research Unit, Pfizer Inc., Cambridge, MA, United States., Feliers D; Internal Medicine Research Unit, Pfizer Inc., Cambridge, MA, United States., Piper M; Internal Medicine Research Unit, Pfizer Inc., Cambridge, MA, United States., Schaub JA; Department of Internal Medicine, Division of Nephrology, University of Michigan, Ann Arbor, MI 48109, USA., Zhou Z; Department of Molecular Biology, Princeton University, Princeton, NJ 08544, USA.; Lewis-Sigler Institute of Integrative Genomics, Princeton University, Princeton, NJ 08544, USA., Mao W; Princeton Precision Health, Princeton University, Princeton, NJ 08544, USA., Chen X; Lewis-Sigler Institute of Integrative Genomics, Princeton University, Princeton, NJ 08544, USA.; Center for Computational Biology, Flatiron Institute, Simons Foundation, New York, NY 10010, USA., Sealfon RSG; Lewis-Sigler Institute of Integrative Genomics, Princeton University, Princeton, NJ 08544, USA.; Center for Computational Biology, Flatiron Institute, Simons Foundation, New York, NY 10010, USA., Menon R; Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI 48109, USA., Nair V; Department of Internal Medicine, Division of Nephrology, University of Michigan, Ann Arbor, MI 48109, USA.; Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI 48109, USA., Eddy S; Division of Nephrology, Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan, USA., Alakwaa FM; Division of Nephrology, Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan, USA., Pyle L; University of Washington Medicine Diabetes Institute, Seattle, WA 98109, USA., Choi YJ; University of Washington Medicine Diabetes Institute, Seattle, WA 98109, USA., Bjornstad P; University of Washington Medicine Diabetes Institute and Seattle Children's Research Institute, Seattle, WA 98109, USA., Alpers CE; Department of Laboratory Medicine and Pathology, University of Washington, Seattle, WA 98195., Bitzer M; University of Michigan., Bomback AS; Division of Nephrology, Columbia University Irving Medical Center, New York, NY, USA., Caramori ML; Department of Endocrinology and Metabolism, Cleveland Clinic Foundation, Cleveland, OH, USA.; Department of Internal Medicine, Division of Diabetes, Endocrinology and Metabolism, University of Minnesota, Minneapolis, MN, USA., Demeke D; Department of Pathology, University of Michigan, Ann Arbor, MI 48109, USA., Fogo AB; Department. Of Pathology, Microbiology and Immunology, Vanderbilt University Medical Center, Nashville, TN, USA., Herlitz LC; Cleveland Clinic., Kiryluk K; Department of Medicine, Division of Nephrology, Vagelos College of Physicians & Surgeons, Columbia University., Lash JP; Department of Medicine, University of Illinois Chicago, Chicago, Illinois., Murugan R; University of Pittsburgh., O'Toole JF; Department of Kidney Medicine, Medical Specialties Institute, Cleveland Clinic & Department of Molecular Medicine, Case Western Reserve University School of Medicine, Cleveland, OH., Palevsky PM; Renal-Electrolyte Division, Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA., Parikh CR; Department of Medicine, Johns Hopkins School of Medicine, Baltimore, US., Rosas SE; Kidney and Hypertension Unit, Joslin Diabetes Center and Harvard Medical School, Boston, MA 02215, USA., Rosenberg AZ; Department of Pathology, Johns Hopkins University School of Medicine Baltimore, MD, USA., Sedor JR; Department of Kidney Medicine, Medical Specialties Institute, Cleveland Clinic & Department of Molecular Medicine, Case Western Reserve University School of Medicine, Cleveland, OH., Vazquez MA; Nephrology Division, University of Texas Southwestern Medical Center., Waikar SS; Section of Nephrology, Boston Medical Center and Boston University Chobanian & Avedisian School of Medicine., Wilson FP; Clinical and Translational Research Accelerator, Department of Medicine, Yale School of Medicine, New Haven, CT., Hodgin JB; Department of Pathology, University of Michigan, Ann Arbor, MI 48109, USA., Barisoni L; Department of Pathology, Division of AI & Computational Pathology, Department of Medicine, Division of Nephrology, Duke University, Durham, NC, USA., Himmelfarb J; Barbara T. Murphy Division of Nephrology, Samuel Bronfman Department of Medicine, Icahn School of Medicine at Mount Sinai., Jain S; Division of Nephrology, Department of Medicine, Washington University School of Medicine, St. Louis, MO 63110, USA.; Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO 63110, USA.; Department of Pediatrics, Washington University School of Medicine, St. Louis, MO 63110, USA.; Kidney Translational Research Center, Washington University School of Medicine, St. Louis, MO 63110, USA., Ju W; Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI 48109, USA.; Division of Nephrology, Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan, USA., Troyanskaya OG; Lewis-Sigler Institute of Integrative Genomics, Princeton University, Princeton, NJ 08544, USA.; Princeton Precision Health, Princeton University, Princeton, NJ 08544, USA.; Center for Computational Biology, Flatiron Institute, Simons Foundation, New York, NY 10010, USA.; Department of Computer Science, Princeton University, Princeton, NJ 08544, USA., Kretzler M; Department of Internal Medicine, Division of Nephrology, University of Michigan, Ann Arbor, MI 48109, USA.; Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI 48109, USA.; Co-senior authors: Matthias Kretzler, Michael T. Eadon, Julio Saez-Rodriguez., Eadon MT; Department of Medicine, Indiana University School of Medicine, Indianapolis, IN 46202, USA.; Co-senior authors: Matthias Kretzler, Michael T. Eadon, Julio Saez-Rodriguez., Saez-Rodriguez J; Heidelberg University, Faculty of Medicine, and Heidelberg University Hospital, Institute for Computational Biomedicine, Heidelberg, Germany.; European Molecular Biology Laboratory, European Bioinformatics Institute (EMBL-EBI), Hinxton, Cambridgeshire, U.K.; Co-senior authors: Matthias Kretzler, Michael T. Eadon, Julio Saez-Rodriguez.

Πηγή: MedRxiv : the preprint server for health sciences [medRxiv] 2026 Mar 06. Date of Electronic Publication: 2026 Mar 06.

Τύπος έκδοσης: Journal Article; Preprint

Στοιχεία περιοδικού: Country of Publication: United States NLM ID: 101767986 Publication Model: Electronic Cited Medium: Internet NLM ISO Abbreviation: medRxiv Subsets: PubMed not MEDLINE

Editorial: Hands-on Training Program.

Συγγραφείς: Kumiko Hayashi

Πηγή: Biophysics & Physicobiology; 2024 Supplement, Vol. 21, p1-10, 10p

Θεματικοί όροι: Life sciences, Grants in aid (Public finance), Nanoscience, Solid state physics, Optical tweezers

Analyzing force measurements of multi-cellular clusters comprising indeterminate geometries

Συγγραφείς: Brill-Karniely, Yifat^{Aff1, Aff2, IDs10237023017649_cor1}, Tischenko, Katerina^Aff1, Benny, Ofra^{Aff1, IDs10237023017649_cor3}

Πηγή: Biomechanics and Modeling in Mechanobiology. 23(1):145-155

Developmental diseases and the hypothetical Master Development Program

Συγγραφείς: Parris, George E. ^⁎

Πηγή: In Medical Hypotheses 2010 74(3):564-573

Metabolic coordination and phase transitions in spatially distributed multi-cellular systems

Συγγραφείς: Narayanankutty, Krishnadev^{Aff1, Aff2}, Pereiro-Morejon, José Antonio^{Aff3, Aff4}, Ferrero-Fernández, Arián^{Aff1, Aff2}, Onesto, Valentina^Aff5, Forciniti, Stefania^Aff5, del Mercato, Loretta L.^Aff5, Mulet, Roberto^Aff6, De Martino, Andrea^{Aff7, Aff8, IDs4200502502133x_cor1}, Tourigny, David S.^{Aff9, IDs4200502502133x_cor2}, De Martino, Daniele^{Aff1, Aff10, IDs4200502502133x_cor3}

Πηγή: Communications Physics. 8(1)

An exploratory simulation of the optimization of leukocyte transmigration, indicating that barrier routing is governed by context-dependent biochemical cues rather than hardwired programs.

Συγγραφείς: Religa, Piotr, Mickael, Michel-Edwar, Kubick, Norwin, Horbańczuk, Jarosław Olav, Sacharczuk, Mariusz

Πηγή: Frontiers in Immunology; 2026, p1-15, 15p

Spatial mapping of Ethiopian cutaneous leishmaniasis lesions reveals distinct tissue level immune programs.

Συγγραφείς: Dey, Nidhi S., Pham, Thao-Thy, Dey, Shoumit, Kassa, Mekibib, Mekonnen, Tigist, Fikre, Helina, Monsieurs, Pieter, Consortium, Spatial CL, Pareyn, Myrthe, van Griensven, Johan, Domagalska, Malgorzata, Dujardin, Jean-Claude, Asres, Mezgebu Silamsaw, Woldetensay, Mikias, Kaye, Paul M., Adriaensen, Wim

Πηγή: Frontiers in Immunology; 2026, p1-22, 22p

Θεματικοί όροι: Immunopathology, Immune response, Skin injuries, Ethiopians, RNA sequencing, Cutaneous leishmaniasis, Granuloma, Tissue remodeling

Developing multi-cellular tumor spheroid model (MCTS) in the chitosan/collagen/alginate (CCA) fibrous scaffold for anticancer drug screening

Συγγραφείς: Wang, Jian-Zheng ^{a, b, c, ⁎}, Zhu, Yu-Xia ^{a, b, c}, Ma, Hui-Chao ^{b, c}, Chen, Si-Nan ^{b, c}, Chao, Ji-Ye ^{b, c}, Ruan, Wen-Ding ^{b, c}, Wang, Duo ^{b, c}, Du, Feng-guang ^{b, c}, Meng, Yue-Zhong ^d

Πηγή: In Materials Science & Engineering C 1 May 2016 62:215-225

Single-cell fixed RNA profiling of the osteosarcoma clinical Spectrum identifies ADAMTS12 and RNASE1 as key drivers of the metastatic niche

Συγγραφείς: Van Khanh, Nguyen ^{a, b}, Dung, Tran Trung ^{c, d}, Hai, Hoang ^a, Sang, Nguyen Tran Quang ^{a, d}, Thanh, Tran Duc ^{c, d}, Quang, Dang Minh ^{c, d}, Ha, Nguyen Thi ^a, Chi, Nguyen Bui Tam ^a, Anh, Pham Tuan ^a, Duc, Pham Minh ^{a, e}, Van Bao, Tran ^a, Huyen, Tran Dang Anh ^a, Phuong, Vu Thi ^b, Hien, Ha Thi Thu ^b, Phuong, Le Thi ^b, Nhung, Nguyen Thi Hong ^f, Kawada, Norifumi ^g, Thuy, Le Thi Thanh ^{a, ⁎}

Πηγή: In Journal of Bone Oncology August 2026 59

Cell and tissue mechanics in 3-D organ morphogenesis: Insights from Drosophila pupal retina development

Συγγραφείς: Decker, Jacob R., Altinok, Irmak, Rebay, Ilaria ^⁎

Πηγή: In Developmental Biology August 2026 536:142-154

Beyond β-Adrenergic Receptor Brake: Compartment-Selective GRK2 Programs from Heart Failure to Cardio-Oncology.

Συγγραφείς: Dotson, Cody Reid, Underwood, Lilly, Sato, Priscila Y.

Πηγή: Kinases & Phosphatases; Sep2026, Vol. 4 Issue 3, p19, 19p

Θεματικοί όροι: G protein-coupled receptor kinases, Cardio-oncology, Beta adrenoceptors, Heart failure, Physiology, Cell communication

Multi-type branching models to describe cell differentiation programs

Συγγραφείς: Nordon, Robert E. ^{a, ⁎}, Ko, Kap-Hyoun ^a, Odell, Ross ^a, Schroeder, Timm ^b

Πηγή: In Journal of Theoretical Biology 2011 277(1):7-18

Multi-Cellular 3D Flat-Knitted Composite Panels Strengthened by PU-Foam: Manufacturing, Testing and Simulating

Συγγραφείς: Raji, Atefeh^Aff1, Hasani, Hossein^{Aff1, IDs10443024102045_cor2}, Hassanzadeh, Sanaz^Aff1

Πηγή: Applied Composite Materials: An International Journal for the Science and Application of Composite Materials. :1-22

Multi-modal comparison of molecular programs driving nurse cell death and clearance in Drosophila melanogaster oogenesis.

Συγγραφείς: Bandyadka, Shruthi^1,2 (AUTHOR), Lebo, Diane P. V.² (AUTHOR), Mondragon, Albert A.^2,3 (AUTHOR), Serizier, Sandy B.^2,3 (AUTHOR), Kwan, Julian⁴ (AUTHOR), Peterson, Jeanne S.² (AUTHOR), Chasse, Alexandra Y.^2,3 (AUTHOR), Jenkins, Victoria² (AUTHOR), Calikyan, Anoush² (AUTHOR), Ortega, Anthony J.² (AUTHOR), Campbell, Joshua D.⁵ (AUTHOR), Emili, Andrew^2,4,6 (AUTHOR), McCall, Kimberly² (AUTHOR) kmccall@bu.edu

Πηγή: PLoS Genetics. 1/3/2025, Vol. 21 Issue 1, p1-32. 32p.

Θεματικοί όροι: *Apoptosis, *Drosophila melanogaster, *Drosophilidae, *Cell death, *Somatic cells

Matrix stiffness may drive multi-cellular crosstalk via YAP signaling in biliary atresia liver fibrosis: a mechanistic review.

Συγγραφείς: Cheng, Jiwen

Πηγή: Frontiers in Cell & Developmental Biology; 2026, p1-12, 12p

Θεματικοί όροι: Extracellular matrix, YAP signaling proteins, Hepatic fibrosis, Bile ducts, Liver cells, Biliary atresia

Relationship of parasites and pathologies to contaminant body burden in sentinel bivalves: NOAA Status and Trends ‘Mussel Watch’ Program

Συγγραφείς: Kim, Yungkul ^{a, ⁎}, Powell, Eric N. ^a, Wade, Terry L. ^b, Presley, Bobby J. ^c

Πηγή: In Marine Environmental Research 2008 65(2):101-127