Protocol for identifying cellular reprogramming minimal networks using combinatorial transcription factor screening

Συγγραφείς: Altman, Abigail R., Author, Pértiga-Cabral, Diogo, Author, Pereira, Carlos Filipe, Author, Kurochkin, Ilia, Author, Lund University, Faculty of Medicine, Centre for Research Infrastructure in Health and Life Sciences (CRI), WCMM-Wallenberg Centre for Molecular Medicine, Lunds universitet, Medicinska fakulteten, Centre for Research Infrastructure in Health and Life Sciences (CRI), WCMM- Wallenberg center för molekylär medicinsk forskning, Originator, Lund University, Faculty of Medicine, Department of Laboratory Medicine, Department of Immuno oncology, Cell Reprogramming in Hematopoiesis and Immunity, Lunds universitet, Medicinska fakulteten, Institutionen för laboratoriemedicin, Avdelningen för immunonkologi, Cellulär omprogrammering i hematopoes och immunitet, Originator, Lund University, Profile areas and other strong research environments, Strategic research areas (SRA), StemTherapy: National Initiative on Stem Cells for Regenerative Therapy, Lunds universitet, Profilområden och andra starka forskningsmiljöer, Strategiska forskningsområden (SFO), StemTherapy: National Initiative on Stem Cells for Regenerative Therapy, Originator, Lund University, Profile areas and other strong research environments, Other Strong Research Environments, LUCC: Lund University Cancer Centre, Lunds universitet, Profilområden och andra starka forskningsmiljöer, Övriga starka forskningsmiljöer, LUCC: Lunds universitets cancercentrum, Originator

Συνεισφορές: Altman, Abigail R., Author, Pértiga-Cabral, Diogo, Author, Pereira, Carlos Filipe, Author, Kurochkin, Ilia, Author, Lund University, Faculty of Medicine, Centre for Research Infrastructure in Health and Life Sciences (CRI), WCMM-Wallenberg Centre for Molecular Medicine, Lunds universitet, Medicinska fakulteten, Centre for Research Infrastructure in Health and Life Sciences (CRI), WCMM- Wallenberg center för molekylär medicinsk forskning, Originator, Lund University, Faculty of Medicine, Department of Laboratory Medicine, Department of Immuno oncology, Cell Reprogramming in Hematopoiesis and Immunity, Lunds universitet, Medicinska fakulteten, Institutionen för laboratoriemedicin, Avdelningen för immunonkologi, Cellulär omprogrammering i hematopoes och immunitet, Originator, Lund University, Profile areas and other strong research environments, Strategic research areas (SRA), StemTherapy: National Initiative on Stem Cells for Regenerative Therapy, Lunds universitet, Profilområden och andra starka forskningsmiljöer, Strategiska forskningsområden (SFO), StemTherapy: National Initiative on Stem Cells for Regenerative Therapy, Originator, Lund University, Profile areas and other strong research environments, Other Strong Research Environments, LUCC: Lund University Cancer Centre, Lunds universitet, Profilområden och andra starka forskningsmiljöer, Övriga starka forskningsmiljöer, LUCC: Lunds universitets cancercentrum, Originator

Πηγή: STAR Protocols. 7(2)

Θεματικοί όροι: Medical and Health Sciences, Basic Medicine, Cell and Molecular Biology, Medicin och hälsovetenskap, Medicinska och farmaceutiska grundvetenskaper, Cell- och molekylärbiologi

Σύνδεσμος πρόσβασης: https://doi.org/10.1016/j.xpro.2026.104527

[Systemic Reprogramming of Cellular Senescence: Coordinated Regulation of Metabolism, Epigenetics, and Proteostasis].

Μεταγλωττισμένος Τίτλος: 细胞衰老的系统性重编程：代谢、表观遗传与蛋白稳态的协同调控.

Συγγραφείς: Zheng Y; •（） （ 610072）Department of Geriatric Cardiology, Sichuan Academy of Medical Sciences & Sichuan Provincial People's Hospital (Affiliated Hospital of University of Electronic Science and Technology of China), Chengdu 610072, China., Liu Q; •（） （ 610072）Department of Geriatric Cardiology, Sichuan Academy of Medical Sciences & Sichuan Provincial People's Hospital (Affiliated Hospital of University of Electronic Science and Technology of China), Chengdu 610072, China., Wang R; •（） （ 610072）Department of Geriatric Cardiology, Sichuan Academy of Medical Sciences & Sichuan Provincial People's Hospital (Affiliated Hospital of University of Electronic Science and Technology of China), Chengdu 610072, China., Sun C; •（） （ 610072）Department of Geriatric Cardiology, Sichuan Academy of Medical Sciences & Sichuan Provincial People's Hospital (Affiliated Hospital of University of Electronic Science and Technology of China), Chengdu 610072, China.

Πηγή: Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition [Sichuan Da Xue Xue Bao Yi Xue Ban] 2026 Jul 20; Vol. 57 (4), pp. 915-924.

Τύπος έκδοσης: Journal Article; Review; English Abstract

Στοιχεία περιοδικού: Publisher: Sichuan da xue xue bao (yi xue ban) bian ji bu Country of Publication: China NLM ID: 101162609 Publication Model: Print Cited Medium: Print ISSN: 1672-173X (Print) Linking ISSN: 1672173X NLM ISO Abbreviation: Sichuan Da Xue Xue Bao Yi Xue Ban Subsets: MEDLINE

Ιατρικοί όροι (MeSH): Cellular Senescence*/genetics , Cellular Senescence*/physiology , Proteostasis*/genetics , Cellular Reprogramming*/genetics , Epigenesis, Genetic*, NAD/metabolism ; Humans ; Kruppel-Like Factor 4 ; Metabolic Reprogramming ; Animals

The Lactate-lactylation circuitry in kidney fibrosis: cellular crosstalk from tubular metabolic reprogramming to macrophage effector functions.

Συγγραφείς: Shang Y; Department of Nephrology, The First Affiliated Hospital of Zhejiang, Chinese Medical University (Zhejiang Provincial Hospital of Chinese Medicine), Hangzhou, 310006, Zhejiang, China.; Zhejiang Key Laboratory of Research and Translation for Kidney Deficiency-Stasis-Turbidity Disease; Zhejiang-Macau International Joint Laboratory of Integrated Traditional Chinese and Western Medicine for Nephrology and Immunology; Zhejiang Chinese Medical University Integrated Research and Clinical Laboratory for Precision Prevention and Treatment of Metabolic and Kidney Diseases, Zhejiang Chinese Medical University, Hangzhou, 310006, Zhejiang, China., Wang Y; Department of Nephrology, The First Affiliated Hospital of Zhejiang, Chinese Medical University (Zhejiang Provincial Hospital of Chinese Medicine), Hangzhou, 310006, Zhejiang, China.; Zhejiang Key Laboratory of Research and Translation for Kidney Deficiency-Stasis-Turbidity Disease; Zhejiang-Macau International Joint Laboratory of Integrated Traditional Chinese and Western Medicine for Nephrology and Immunology; Zhejiang Chinese Medical University Integrated Research and Clinical Laboratory for Precision Prevention and Treatment of Metabolic and Kidney Diseases, Zhejiang Chinese Medical University, Hangzhou, 310006, Zhejiang, China., Luo Q; Department of Nephrology, The First Affiliated Hospital of Zhejiang, Chinese Medical University (Zhejiang Provincial Hospital of Chinese Medicine), Hangzhou, 310006, Zhejiang, China.; Zhejiang Key Laboratory of Research and Translation for Kidney Deficiency-Stasis-Turbidity Disease; Zhejiang-Macau International Joint Laboratory of Integrated Traditional Chinese and Western Medicine for Nephrology and Immunology; Zhejiang Chinese Medical University Integrated Research and Clinical Laboratory for Precision Prevention and Treatment of Metabolic and Kidney Diseases, Zhejiang Chinese Medical University, Hangzhou, 310006, Zhejiang, China., He R; Department of Nephrology, The First Affiliated Hospital of Zhejiang, Chinese Medical University (Zhejiang Provincial Hospital of Chinese Medicine), Hangzhou, 310006, Zhejiang, China.; Zhejiang Key Laboratory of Research and Translation for Kidney Deficiency-Stasis-Turbidity Disease; Zhejiang-Macau International Joint Laboratory of Integrated Traditional Chinese and Western Medicine for Nephrology and Immunology; Zhejiang Chinese Medical University Integrated Research and Clinical Laboratory for Precision Prevention and Treatment of Metabolic and Kidney Diseases, Zhejiang Chinese Medical University, Hangzhou, 310006, Zhejiang, China., Wang S; Department of Nephrology, The First Affiliated Hospital of Zhejiang, Chinese Medical University (Zhejiang Provincial Hospital of Chinese Medicine), Hangzhou, 310006, Zhejiang, China.; Zhejiang Key Laboratory of Research and Translation for Kidney Deficiency-Stasis-Turbidity Disease; Zhejiang-Macau International Joint Laboratory of Integrated Traditional Chinese and Western Medicine for Nephrology and Immunology; Zhejiang Chinese Medical University Integrated Research and Clinical Laboratory for Precision Prevention and Treatment of Metabolic and Kidney Diseases, Zhejiang Chinese Medical University, Hangzhou, 310006, Zhejiang, China., Wang B; Department of Nephrology, The First Affiliated Hospital of Zhejiang, Chinese Medical University (Zhejiang Provincial Hospital of Chinese Medicine), Hangzhou, 310006, Zhejiang, China.; Zhejiang Key Laboratory of Research and Translation for Kidney Deficiency-Stasis-Turbidity Disease; Zhejiang-Macau International Joint Laboratory of Integrated Traditional Chinese and Western Medicine for Nephrology and Immunology; Zhejiang Chinese Medical University Integrated Research and Clinical Laboratory for Precision Prevention and Treatment of Metabolic and Kidney Diseases, Zhejiang Chinese Medical University, Hangzhou, 310006, Zhejiang, China., Lin W; Department of Nephrology, The First Affiliated Hospital of Zhejiang, Chinese Medical University (Zhejiang Provincial Hospital of Chinese Medicine), Hangzhou, 310006, Zhejiang, China.; Zhejiang Key Laboratory of Research and Translation for Kidney Deficiency-Stasis-Turbidity Disease; Zhejiang-Macau International Joint Laboratory of Integrated Traditional Chinese and Western Medicine for Nephrology and Immunology; Zhejiang Chinese Medical University Integrated Research and Clinical Laboratory for Precision Prevention and Treatment of Metabolic and Kidney Diseases, Zhejiang Chinese Medical University, Hangzhou, 310006, Zhejiang, China., Zhou Y; Department of Nephrology, The First Affiliated Hospital of Zhejiang, Chinese Medical University (Zhejiang Provincial Hospital of Chinese Medicine), Hangzhou, 310006, Zhejiang, China.; Zhejiang Key Laboratory of Research and Translation for Kidney Deficiency-Stasis-Turbidity Disease; Zhejiang-Macau International Joint Laboratory of Integrated Traditional Chinese and Western Medicine for Nephrology and Immunology; Zhejiang Chinese Medical University Integrated Research and Clinical Laboratory for Precision Prevention and Treatment of Metabolic and Kidney Diseases, Zhejiang Chinese Medical University, Hangzhou, 310006, Zhejiang, China., He Q; Department of Nephrology, The First Affiliated Hospital of Zhejiang, Chinese Medical University (Zhejiang Provincial Hospital of Chinese Medicine), Hangzhou, 310006, Zhejiang, China.; Zhejiang Key Laboratory of Research and Translation for Kidney Deficiency-Stasis-Turbidity Disease; Zhejiang-Macau International Joint Laboratory of Integrated Traditional Chinese and Western Medicine for Nephrology and Immunology; Zhejiang Chinese Medical University Integrated Research and Clinical Laboratory for Precision Prevention and Treatment of Metabolic and Kidney Diseases, Zhejiang Chinese Medical University, Hangzhou, 310006, Zhejiang, China., He Q; Department of Nephrology, The First Affiliated Hospital of Zhejiang, Chinese Medical University (Zhejiang Provincial Hospital of Chinese Medicine), Hangzhou, 310006, Zhejiang, China. qianghe1973@126.com.; Zhejiang Key Laboratory of Research and Translation for Kidney Deficiency-Stasis-Turbidity Disease; Zhejiang-Macau International Joint Laboratory of Integrated Traditional Chinese and Western Medicine for Nephrology and Immunology; Zhejiang Chinese Medical University Integrated Research and Clinical Laboratory for Precision Prevention and Treatment of Metabolic and Kidney Diseases, Zhejiang Chinese Medical University, Hangzhou, 310006, Zhejiang, China. qianghe1973@126.com., Jin J; Department of Nephrology, The First Affiliated Hospital of Zhejiang, Chinese Medical University (Zhejiang Provincial Hospital of Chinese Medicine), Hangzhou, 310006, Zhejiang, China. lang_018@163.com.; Zhejiang Key Laboratory of Research and Translation for Kidney Deficiency-Stasis-Turbidity Disease; Zhejiang-Macau International Joint Laboratory of Integrated Traditional Chinese and Western Medicine for Nephrology and Immunology; Zhejiang Chinese Medical University Integrated Research and Clinical Laboratory for Precision Prevention and Treatment of Metabolic and Kidney Diseases, Zhejiang Chinese Medical University, Hangzhou, 310006, Zhejiang, China. lang_018@163.com.

Πηγή: Seminars in immunopathology [Semin Immunopathol] 2026 Aug 24; Vol. 48 (1). Date of Electronic Publication: 2026 Aug 24.

Τύπος έκδοσης: Journal Article; Review

Στοιχεία περιοδικού: Publisher: Springer Country of Publication: Germany NLM ID: 101308769 Publication Model: Electronic Cited Medium: Internet ISSN: 1863-2300 (Electronic) Linking ISSN: 18632297 NLM ISO Abbreviation: Semin Immunopathol Subsets: MEDLINE

Ιατρικοί όροι (MeSH): Macrophages*/metabolism , Macrophages*/immunology , Kidney Tubules*/metabolism , Kidney Tubules*/pathology , Kidney Diseases*/metabolism , Kidney Diseases*/etiology , Kidney Diseases*/pathology , Cell Communication* , Cellular Reprogramming*, Humans ; Metabolic Reprogramming ; Fibrosis ; Animals ; Signal Transduction

Developmental stage-dependent cellular plasticity governs β-cell reprogramming efficiency in human fibroblasts.

Συγγραφείς: Raj N; Laboratory for Stem Cell Engineering and Regenerative Medicine, Department of Biosciences and Bioengineering, Indian Institute of Technology Guwahati, Guwahati, Assam, 781039, India. Electronic address: naveenraj@iitg.ac.in., Panneerselvam DS; Laboratory for Stem Cell Engineering and Regenerative Medicine, Department of Biosciences and Bioengineering, Indian Institute of Technology Guwahati, Guwahati, Assam, 781039, India. Electronic address: p.dhaya@iitg.ac.in., Thummer RP; Laboratory for Stem Cell Engineering and Regenerative Medicine, Department of Biosciences and Bioengineering, Indian Institute of Technology Guwahati, Guwahati, Assam, 781039, India. Electronic address: rthu@iitg.ac.in.

Πηγή: Biochemical and biophysical research communications [Biochem Biophys Res Commun] 2026 Sep 03; Vol. 829, pp. 154188. Date of Electronic Publication: 2026 Jun 23.

Τύπος έκδοσης: Journal Article

Στοιχεία περιοδικού: Publisher: Elsevier Country of Publication: United States NLM ID: 0372516 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1090-2104 (Electronic) Linking ISSN: 0006291X NLM ISO Abbreviation: Biochem Biophys Res Commun Subsets: MEDLINE

Ιατρικοί όροι (MeSH): Fibroblasts*/cytology , Fibroblasts*/metabolism , Insulin-Secreting Cells*/cytology , Insulin-Secreting Cells*/metabolism , Cellular Reprogramming* , Cell Plasticity*, Lentivirus/genetics ; Trans-Activators/genetics ; Trans-Activators/metabolism ; Nerve Tissue Proteins/genetics ; Nerve Tissue Proteins/metabolism ; Homeodomain Proteins/genetics ; Homeodomain Proteins/metabolism ; Basic Helix-Loop-Helix Proteins/genetics ; Basic Helix-Loop-Helix Proteins/metabolism ; Humans ; Cells, Cultured ; Cell Differentiation

IRAK4 constrains cellular plasticity during chemically-induced cell fate reprogramming into multiple lineages.

Συγγραφείς: Huang C; Zhejiang Provincial Key Laboratory of Medical Genetics, Key Laboratory of Laboratory Medicine, Ministry of Education, School of Laboratory Medicine and Life Sciences, Wenzhou Medical University, 325035, Wenzhou, Zhejiang, China. huangchuanshu@ojlab.AC.cn.; Oujiang Laboratory (Zhejiang Lab for Regenerative Medicine, Vision and Brain Health), Wenzhou, Zhejiang, 325035, China. huangchuanshu@ojlab.AC.cn., Han X; Oujiang Laboratory (Zhejiang Lab for Regenerative Medicine, Vision and Brain Health), Wenzhou, Zhejiang, 325035, China., Wang T; Key Laboratory of Laboratory Medicine, Ministry of Education, Institute of Genomic Medicine, Wenzhou Medical University, Wenzhou, Zhejiang, 325035, China., Zhao Y; State Key Laboratory of Natural and Biomimetic Drugs, Ministry of Education Key Laboratory of Cell Proliferation and Differentiation, Beijing Advanced Center of Cellular Homeostasis and Aging-Related Diseases, Institute of Advanced Clinical Medicine, Peking University, Beijing, 100871, China. yangzhao@pku.edu.cn., Li J; Zhejiang Provincial Key Laboratory of Medical Genetics, Key Laboratory of Laboratory Medicine, Ministry of Education, School of Laboratory Medicine and Life Sciences, Wenzhou Medical University, 325035, Wenzhou, Zhejiang, China. jun.li@wmu.edu.cn.; Oujiang Laboratory (Zhejiang Lab for Regenerative Medicine, Vision and Brain Health), Wenzhou, Zhejiang, 325035, China. jun.li@wmu.edu.cn.

Πηγή: EMBO reports [EMBO Rep] 2026 Aug; Vol. 27 (16), pp. 4903-4934. Date of Electronic Publication: 2026 Jul 15.

Τύπος έκδοσης: Journal Article

Στοιχεία περιοδικού: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 100963049 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1469-3178 (Electronic) Linking ISSN: 1469221X NLM ISO Abbreviation: EMBO Rep Subsets: MEDLINE

Ιατρικοί όροι (MeSH): Cellular Reprogramming*/drug effects , Cellular Reprogramming*/genetics , Interleukin-1 Receptor-Associated Kinases*/metabolism , Interleukin-1 Receptor-Associated Kinases*/genetics , Interleukin-1 Receptor-Associated Kinases*/antagonists & inhibitors , Cell Lineage*/drug effects , Cell Plasticity*/genetics , Cell Plasticity*/drug effects, Fibroblasts/cytology ; Fibroblasts/metabolism ; Fibroblasts/drug effects ; Hepatocytes/cytology ; Hepatocytes/metabolism ; Endoderm/cytology ; Endoderm/metabolism ; Neurons/cytology ; Neurons/metabolism ; Animals ; Mice ; Cell Cycle ; Cell Differentiation

AAV Vectors in Regenerative Medicine and Cellular Reprogramming: Potential, Pitfalls, and Specificity Constraints.

Συγγραφείς: Abdelnaby M; Department of Biological and Medical Physics, Moscow Institute of Physics and Technology (State University), Institutskiy Per., 141701 Dolgoprudny, Russia.; Research Institute of Translational Medicine, Pirogov Russian National Research Medical University, Ostrovitianov Street, 117997 Moscow, Russia., Galiakberova A; Research Institute of Translational Medicine, Pirogov Russian National Research Medical University, Ostrovitianov Street, 117997 Moscow, Russia.; Research Institute of Molecular and Cellular Medicine, RUDN University, 117198 Moscow, Russia., Dashinimaev E; Department of Biological and Medical Physics, Moscow Institute of Physics and Technology (State University), Institutskiy Per., 141701 Dolgoprudny, Russia.; Research Institute of Translational Medicine, Pirogov Russian National Research Medical University, Ostrovitianov Street, 117997 Moscow, Russia.; Research Institute of Molecular and Cellular Medicine, RUDN University, 117198 Moscow, Russia.; Medical Institute, Banzarov Buryat State University, 670000 Ulan-Ude, Russia.

Πηγή: International journal of molecular sciences [Int J Mol Sci] 2026 Jul 30; Vol. 27 (15). Date of Electronic Publication: 2026 Jul 30.

Τύπος έκδοσης: Journal Article; Review

Στοιχεία περιοδικού: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067 (Electronic) Linking ISSN: 14220067 NLM ISO Abbreviation: Int J Mol Sci Subsets: MEDLINE

Ιατρικοί όροι (MeSH): Cellular Reprogramming*/genetics , Regenerative Medicine*/methods , Genetic Vectors*/genetics , Dependovirus*/genetics, Genetic Therapy/methods ; Induced Pluripotent Stem Cells/metabolism ; Induced Pluripotent Stem Cells/cytology ; Humans ; Animals ; Gene Transfer Techniques ; Gene Therapy Agents ; Transduction, Genetic

Cellular reprogramming beyond pluripotency.

Συγγραφείς: Núñez-Quintela V; Laboratory of Cell Senescence, Cancer and Aging, Center for Research in Molecular Medicine and Chronic Diseases (CiMUS), University of Santiago de Compostela, Health Research Institute of Santiago de Compostela (IDIS), Santiago de Compostela, Spain. Electronic address: victor.nunez.quintela@rai.usc.es., Li H; Cellular Plasticity in Age-related Pathologies, Department of Developmental and Stem Cell Biology, CNRS UMR 3738, Université Paris Cité, Institut Pasteur, Paris, France., Collado M; Laboratory of Cell Senescence, Cancer and Aging, Center for Research in Molecular Medicine and Chronic Diseases (CiMUS), University of Santiago de Compostela, Health Research Institute of Santiago de Compostela (IDIS), Santiago de Compostela, Spain; Department of Immunology and Oncology (DIO), Centro Nacional de Biotecnología (CNB-CSIC), Madrid, Spain. Electronic address: manuel.collado@usc.es.

Πηγή: Trends in molecular medicine [Trends Mol Med] 2026 Aug; Vol. 32 (8), pp. 810-821. Date of Electronic Publication: 2026 Mar 20.

Τύπος έκδοσης: Journal Article; Review

Στοιχεία περιοδικού: Publisher: Elsevier Science Ltd Country of Publication: England NLM ID: 100966035 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1471-499X (Electronic) Linking ISSN: 14714914 NLM ISO Abbreviation: Trends Mol Med Subsets: MEDLINE

Ιατρικοί όροι (MeSH): Cellular Reprogramming*/genetics , Aging*/genetics , Pluripotent Stem Cells*/cytology , Pluripotent Stem Cells*/metabolism, Humans ; Animals ; Regeneration

[Molecular mechanism of intervertebral disc cell senescence: telomeres, mitochondria, and cellular metabolic reprogramming].

Συγγραφείς: Deng W; Guangzhou University of Chinese Medicine, Guangzhou 510006, China.; Department of Minimally Invasive Spine Surgery, The First Clinical Medical College of Guangzhou University of Chinese Medicine/The First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou 510006, China., Zhu RC; Guangzhou University of Chinese Medicine, Guangzhou 510006, China.; Department of Minimally Invasive Spine Surgery, The First Clinical Medical College of Guangzhou University of Chinese Medicine/The First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou 510006, China., Kong FG; The Second Department of Minimally Invasive Spine Surgery, Luoyang Orthopedic Hospital of Henan Province/Orthopedic Hospital of Henan Province, Zhengzhou 450000, China., Luan JY; Guangzhou University of Chinese Medicine, Guangzhou 510006, China.; The Second Department of Minimally Invasive Spine Surgery, Luoyang Orthopedic Hospital of Henan Province/Orthopedic Hospital of Henan Province, Zhengzhou 450000, China.

Πηγή: Sheng li xue bao : [Acta physiologica Sinica] [Sheng Li Xue Bao] 2026 Jun 25; Vol. 78 (3), pp. 566-578.

Τύπος έκδοσης: Journal Article; Review; English Abstract

Στοιχεία περιοδικού: Publisher: Science Press Country of Publication: China NLM ID: 20730130R Publication Model: Print Cited Medium: Internet ISSN: 0371-0874 (Print) Linking ISSN: 03710874 NLM ISO Abbreviation: Sheng Li Xue Bao Subsets: MEDLINE

Ιατρικοί όροι (MeSH): Cellular Senescence*/physiology , Cellular Senescence*/genetics , Mitochondria*/physiology , Mitochondria*/metabolism , Telomere*/physiology , Intervertebral Disc Degeneration*/metabolism , Intervertebral Disc Degeneration*/pathology , Intervertebral Disc*/cytology , Intervertebral Disc*/metabolism , Cellular Reprogramming*, Humans ; Metabolic Reprogramming ; Animals

Repetitive neuronal activation regulates cellular maturation state via nuclear reprogramming.

Συγγραφείς: Murano T; Division of Systems Medical Science, Center for Medical Science, Fujita Health University, Toyoake, Japan., Hagihara H; Division of Systems Medical Science, Center for Medical Science, Fujita Health University, Toyoake, Japan., Tajinda K; Astellas Research Institute of America, San Diego, CA, USA., Takao K; Department of Behavioral Physiology, Faculty of Medicine, University of Toyama, Toyama, Japan.; Research Center for Idling Brain Science, University of Toyama, Toyama, Japan., Takamiya Y; Division of Systems Medical Science, Center for Medical Science, Fujita Health University, Toyoake, Japan., Katoh K; Artificial Intelligence Research Center, National Institute of Advanced Industrial Science and Technology (AIST), Tsukuba, Japan.; Ph.D. Program in Humanics, School of Integrative and Global Majors, University of Tsukuba, Tsukuba, Japan.; The Exploratory Research Center on Life and Living Systems (ExCELLS), National Institutes of Natural Sciences (NINS), Okazaki, Japan.; Molecular Biosystem Research Institute, National Institute of Advanced Industrial Science and Technology (AIST), Tsukuba, Japan.; Department of Biochemistry and Cell Biology, National Institute of Infectious Diseases (NIID), Tokyo, Japan., Robison AJ; Department of Physiology and Neuroscience Program, Michigan State University, East Lansing, MI, USA., Matsumoto M; Astellas Research Institute of America, San Diego, CA, USA.; Arialys Therapeutics Inc., La Jolla, CA, USA., Namihira M; Artificial Intelligence Research Center, National Institute of Advanced Industrial Science and Technology (AIST), Tsukuba, Japan.; Molecular Biosystem Research Institute, National Institute of Advanced Industrial Science and Technology (AIST), Tsukuba, Japan.; Laboratory of Neural Regeneration and Brain Repair, Division of Biological Science, Graduate School of Science andTechnology, Nara Institute of Science and Technology (NAIST), 8916-5 Takayama-cho, Ikoma, Nara, Japan., Miyakawa T; Division of Systems Medical Science, Center for Medical Science, Fujita Health University, Toyoake, Japan. miyakawa@fujita-hu.ac.jp.

Πηγή: Nature communications [Nat Commun] 2026 Jul 17; Vol. 17 (1). Date of Electronic Publication: 2026 Jul 17.

Τύπος έκδοσης: Journal Article; Research Support, Non-U.S. Gov't

Στοιχεία περιοδικού: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

Ιατρικοί όροι (MeSH): Neurons*/physiology , Neurons*/metabolism , Neurons*/cytology , Dentate Gyrus*/cytology , Dentate Gyrus*/physiology , Dentate Gyrus*/metabolism , Cellular Reprogramming*/physiology, Animals ; Mice ; Optogenetics ; Male ; Mice, Inbred C57BL ; Mice, Knockout

Histone lactylation: A sensor of epigenetic reprogramming mediated by cellular metabolism.

Συγγραφείς: Wang L; Chongqing Key Laboratory of Herbivore Science, College of Animal Science and Technology, Southwest University, Chongqing 400715, China., Song S; Chongqing Key Laboratory of Herbivore Science, College of Animal Science and Technology, Southwest University, Chongqing 400715, China., Yao S; Chongqing Key Laboratory of Herbivore Science, College of Animal Science and Technology, Southwest University, Chongqing 400715, China., Wang Z; Chongqing Key Laboratory of Herbivore Science, College of Animal Science and Technology, Southwest University, Chongqing 400715, China., Li Q; Chongqing Key Laboratory of Herbivore Science, College of Animal Science and Technology, Southwest University, Chongqing 400715, China., Ma Z; Chongqing Key Laboratory of Herbivore Science, College of Animal Science and Technology, Southwest University, Chongqing 400715, China., Li J; Chongqing Key Laboratory of Herbivore Science, College of Animal Science and Technology, Southwest University, Chongqing 400715, China., Li Y; Chongqing Key Laboratory of Herbivore Science, College of Animal Science and Technology, Southwest University, Chongqing 400715, China., Yang M; Chongqing Key Laboratory of Herbivore Science, College of Animal Science and Technology, Southwest University, Chongqing 400715, China., Zhang K; Chongqing Animal Husbandry Technology Extension Station, Chongqing 401121, China., Han Y; Chongqing Key Laboratory of Herbivore Science, College of Animal Science and Technology, Southwest University, Chongqing 400715, China. Electronic address: hyg2015@swu.edu.cn., Xu D; Chongqing Key Laboratory of Herbivore Science, College of Animal Science and Technology, Southwest University, Chongqing 400715, China. Electronic address: xdj2020@swu.edu.cn., Zhao Z; Chongqing Key Laboratory of Herbivore Science, College of Animal Science and Technology, Southwest University, Chongqing 400715, China. Electronic address: zhaozhongquan@swu.edu.cn.

Πηγή: Cellular signalling [Cell Signal] 2026 Jul; Vol. 143, pp. 112483. Date of Electronic Publication: 2026 Mar 13.

Τύπος έκδοσης: Journal Article; Review

Στοιχεία περιοδικού: Publisher: Elsevier Science Ltd Country of Publication: England NLM ID: 8904683 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-3913 (Electronic) Linking ISSN: 08986568 NLM ISO Abbreviation: Cell Signal Subsets: MEDLINE

Ιατρικοί όροι (MeSH): Histones*/metabolism , Epigenesis, Genetic* , Cellular Reprogramming*, Humans ; Animals ; Acetylation ; Protein Processing, Post-Translational ; Transcription, Genetic

A protoplast-based method to visualize early cell biological events in plant cellular reprogramming and regeneration.

Συγγραφείς: Reed KM; School of Plant and Environmental Sciences, Virginia Polytechnic Institute and State University, Blacksburg, VA 24061, USA., Masri AA; School of Plant and Environmental Sciences, Virginia Polytechnic Institute and State University, Blacksburg, VA 24061, USA., Hanrahan AJ; School of Plant and Environmental Sciences, Virginia Polytechnic Institute and State University, Blacksburg, VA 24061, USA., Ng EL; Facility for Advanced Imaging and Microscopy, Fralin Life Sciences Institute, Virginia Polytechnic Institute and State University, Blacksburg, VA 24061, USA., Li M; Donald Danforth Plant Sciences Center, St. Louis, MO 63132, USA., Bargmann BOR; School of Plant and Environmental Sciences, Virginia Polytechnic Institute and State University, Blacksburg, VA 24061, USA.

Πηγή: Development (Cambridge, England) [Development] 2026 Sep 15; Vol. 153 (18). Date of Electronic Publication: 2026 Sep 15.

Τύπος έκδοσης: Journal Article

Στοιχεία περιοδικού: Publisher: Company Of Biologists Limited Country of Publication: England NLM ID: 8701744 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1477-9129 (Electronic) Linking ISSN: 09501991 NLM ISO Abbreviation: Development Subsets: MEDLINE

Ιατρικοί όροι (MeSH): Protoplasts*/metabolism , Protoplasts*/cytology , Protoplasts*/physiology , Arabidopsis*/cytology , Arabidopsis*/physiology , Regeneration*/physiology , Cellular Reprogramming*/physiology , Plant Cells*

Distinct media requirements for dopaminergic neuron reprogramming from human glia and fibroblasts.

Συγγραφείς: Laurin K; Developmental and Regenerative Neurobiology, Lund Stem Cell Center, Department of Experimental Medical Science, Faculty of Medicine, Lund University, Lund, Sweden., Kajtez J; Novo Nordisk Foundation Center for Stem Cell Medicine (reNEW), Department of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Wickham J; Laboratory of Stem Cells and Restorative Neurology, Lund Stem Cell Center, Faculty of Medicine, Lund University, Lund, Sweden., Parmar M; Developmental and Regenerative Neurobiology, Lund Stem Cell Center, Department of Experimental Medical Science, Faculty of Medicine, Lund University, Lund, Sweden., Habekost M; Developmental and Regenerative Neurobiology, Lund Stem Cell Center, Department of Experimental Medical Science, Faculty of Medicine, Lund University, Lund, Sweden. mette.habekost@med.lu.se.; Center for Translational Neuromedicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, 2200, Denmark. mette.habekost@med.lu.se.; Department of Biotechnology and Biomedicine, DTU Bioengineering, Technical University of Denmark, Kgs. Lyngby, 2800, Denmark. mette.habekost@med.lu.se.

Πηγή: Scientific reports [Sci Rep] 2026 Aug 17; Vol. 16 (1). Date of Electronic Publication: 2026 Aug 17.

Τύπος έκδοσης: Journal Article

Στοιχεία περιοδικού: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE

Ιατρικοί όροι (MeSH): Dopaminergic Neurons*/cytology , Dopaminergic Neurons*/metabolism , Dopaminergic Neurons*/drug effects , Fibroblasts*/cytology , Fibroblasts*/metabolism , Fibroblasts*/drug effects , Cellular Reprogramming*/drug effects , Neuroglia*/cytology , Neuroglia*/metabolism , Neuroglia*/drug effects , Culture Media*/pharmacology , Culture Media*/chemistry, Tyrosine 3-Monooxygenase/metabolism ; Dopamine/metabolism ; Humans ; Cells, Cultured ; Cellular Reprogramming Techniques

Functional suppression accompanies internal mitochondrial reorganization during cellular reprogramming.

Συγγραφείς: Diak N; Department of Molecular Biology, Faculty of Medical Sciences in Katowice, Medical University of Silesia, Medykow 18 Street, 40-752, Katowice, Poland., Sieroń L; Department of Molecular Biology, Faculty of Medical Sciences in Katowice, Medical University of Silesia, Medykow 18 Street, 40-752, Katowice, Poland., Janelt K; Department of Molecular Biology, Faculty of Medical Sciences in Katowice, Medical University of Silesia, Medykow 18 Street, 40-752, Katowice, Poland., Chajec L; Faculty of Natural Sciences, Institute of Biology, Biotechnology and Environmental Protection, University of Silesia in Katowice, Bankowa 9, 40-007, Katowice, Poland., Fus-Kujawa A; Department of Molecular Biology, Faculty of Medical Sciences in Katowice, Medical University of Silesia, Medykow 18 Street, 40-752, Katowice, Poland., Dziedzic-Kowalska A; Department of Molecular Biology, Faculty of Medical Sciences in Katowice, Medical University of Silesia, Medykow 18 Street, 40-752, Katowice, Poland., Trybus A; Department of Molecular Biology, Faculty of Medical Sciences in Katowice, Medical University of Silesia, Medykow 18 Street, 40-752, Katowice, Poland., Raszczok K; Department of Molecular Biology, Faculty of Medical Sciences in Katowice, Medical University of Silesia, Medykow 18 Street, 40-752, Katowice, Poland.; Students Scientific Society, Faculty of Medical Sciences, Medical University of Silesia, Katowice, Poland., Bajdak-Rusinek K; Department of Molecular Biology, Faculty of Medical Sciences in Katowice, Medical University of Silesia, Medykow 18 Street, 40-752, Katowice, Poland. kbajdak-rusinek@sum.edu.pl.

Πηγή: Histochemistry and cell biology [Histochem Cell Biol] 2026 Apr 20; Vol. 164 (1). Date of Electronic Publication: 2026 Apr 20.

Τύπος έκδοσης: Journal Article

Στοιχεία περιοδικού: Publisher: Springer Country of Publication: Germany NLM ID: 9506663 Publication Model: Electronic Cited Medium: Internet ISSN: 1432-119X (Electronic) Linking ISSN: 09486143 NLM ISO Abbreviation: Histochem Cell Biol Subsets: MEDLINE

Ιατρικοί όροι (MeSH): Mitochondria*/metabolism , Induced Pluripotent Stem Cells*/metabolism , Induced Pluripotent Stem Cells*/cytology , Cellular Reprogramming*, Fibroblasts/metabolism ; Fibroblasts/cytology ; Reactive Oxygen Species/metabolism ; Humans ; Cells, Cultured ; Membrane Potential, Mitochondrial

A cross-talk between p16High senescence and cellular reprogramming.

Συγγραφείς: Emelyanov A; Institute for Research on Cancer and Aging of Nice (IRCAN), Université Côte d'Azur, INSERM, CNRS, Nice, France., Bulavin DV; Institute for Research on Cancer and Aging of Nice (IRCAN), Université Côte d'Azur, INSERM, CNRS, Nice, France.

Πηγή: Clinical science (London, England : 1979) [Clin Sci (Lond)] 2026 Jun 10; Vol. 140 (6), pp. 1137-1147.

Τύπος έκδοσης: Journal Article; Review

Στοιχεία περιοδικού: Publisher: Portland Press on behalf of the Medical Research Society and the Biochemical Society Country of Publication: England NLM ID: 7905731 Publication Model: Print Cited Medium: Internet ISSN: 1470-8736 (Electronic) Linking ISSN: 01435221 NLM ISO Abbreviation: Clin Sci (Lond) Subsets: MEDLINE

Ιατρικοί όροι (MeSH): Cellular Senescence*/genetics , Cellular Senescence*/physiology , Cyclin-Dependent Kinase Inhibitor p16*/metabolism , Cyclin-Dependent Kinase Inhibitor p16*/genetics , Cellular Reprogramming*, Fibroblasts/metabolism ; Humans ; Kruppel-Like Factor 4 ; Animals ; Epigenesis, Genetic ; Signal Transduction

Wounding activates the HSFA1 transcription factors to promote cellular reprogramming in Arabidopsis.

Συγγραφείς: Coleman D; RIKEN Center for Sustainable Resource Science, 1-7-22 Suehiro-cho, Tsurumi Ward, Yokohama, Kanagawa 230-0045, Japan.; Department of Biological Sciences, Faculty of Science, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033, Japan., Iwase A; RIKEN Center for Sustainable Resource Science, 1-7-22 Suehiro-cho, Tsurumi Ward, Yokohama, Kanagawa 230-0045, Japan.; JST, PRESTO, 7 Goban-cho, Chiyoda-ku, Tokyo 102-0076Japan., Kawamura A; RIKEN Center for Sustainable Resource Science, 1-7-22 Suehiro-cho, Tsurumi Ward, Yokohama, Kanagawa 230-0045, Japan., Takebayashi A; RIKEN Center for Sustainable Resource Science, 1-7-22 Suehiro-cho, Tsurumi Ward, Yokohama, Kanagawa 230-0045, Japan., Chen Y; RIKEN Center for Sustainable Resource Science, 1-7-22 Suehiro-cho, Tsurumi Ward, Yokohama, Kanagawa 230-0045, Japan., Minne M; RIKEN Center for Sustainable Resource Science, 1-7-22 Suehiro-cho, Tsurumi Ward, Yokohama, Kanagawa 230-0045, Japan., Jager KE; Leibniz-Institut für Gemüse- und Zierpflanzenbau, Theodor-Echtermeyer-Weg 1, Großbeeren 14979, Germany., Peng M; Leibniz-Institut für Gemüse- und Zierpflanzenbau, Theodor-Echtermeyer-Weg 1, Großbeeren 14979, Germany., Kodama Y; Center for Bioscience Research and Education, Utsunomiya University, 350 Mine-machi, Utsunomiya, Tochigi 331-8505, Japan., Favero DS; RIKEN Center for Sustainable Resource Science, 1-7-22 Suehiro-cho, Tsurumi Ward, Yokohama, Kanagawa 230-0045, Japan., Takahashi T; RIKEN Center for Sustainable Resource Science, 1-7-22 Suehiro-cho, Tsurumi Ward, Yokohama, Kanagawa 230-0045, Japan., Ikeuchi M; RIKEN Center for Sustainable Resource Science, 1-7-22 Suehiro-cho, Tsurumi Ward, Yokohama, Kanagawa 230-0045, Japan.; Division of Biological Sciences, Graduate School of Science and Technology, Nara Institute of Science and Technology, 8916-5, Takayama-cho, Ikoma, Nara 630-0192, Japan., Suzuki T; Department of Biological Chemistry, College of Bioscience and Biotechnology, Chubu University, 1200 Matsumoto-cho, Kasugai, Aichi 487-8501, Japan., Ohama N; Graduate School of Agricultural and Life Sciences, The University of Tokyo, Bunkyo-ku, Tokyo 113-8657, Japan., Yamaguchi-Shinozaki K; Graduate School of Agricultural and Life Sciences, The University of Tokyo, Bunkyo-ku, Tokyo 113-8657, Japan., Wigge PA; Leibniz-Institut für Gemüse- und Zierpflanzenbau, Theodor-Echtermeyer-Weg 1, Großbeeren 14979, Germany.; Institute of Biochemistry and Biology, University of Potsdam, Karl-Liebknecht-Str. 24-25 Haus 25, Raum B1.11-12, Potsdam 14476, Germany., De Veylder L; Department of Plant Biotechnology and Bioinformatics, Ghent University, Gent, Belgium.; Center for Plant Systems Biology, VIB, Gent, Belgium., Sugimoto K; RIKEN Center for Sustainable Resource Science, 1-7-22 Suehiro-cho, Tsurumi Ward, Yokohama, Kanagawa 230-0045, Japan.; Department of Biological Sciences, Faculty of Science, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033, Japan.

Πηγή: The Plant cell [Plant Cell] 2026 Jun 02; Vol. 38 (6).

Τύπος έκδοσης: Journal Article

Στοιχεία περιοδικού: Publisher: Oxford University Press Country of Publication: England NLM ID: 9208688 Publication Model: Print Cited Medium: Internet ISSN: 1532-298X (Electronic) Linking ISSN: 10404651 NLM ISO Abbreviation: Plant Cell Subsets: MEDLINE

Ιατρικοί όροι (MeSH): Arabidopsis*/genetics , Arabidopsis*/metabolism , Arabidopsis*/physiology , Arabidopsis Proteins*/metabolism , Arabidopsis Proteins*/genetics , Cellular Reprogramming*/genetics , Cellular Reprogramming*/physiology , Heat Shock Transcription Factors*/metabolism , Heat Shock Transcription Factors*/genetics , Transcription Factors*/metabolism , Transcription Factors*/genetics, Gene Expression Regulation, Plant/genetics

Integrative methylation and transcriptomic analysis reveals key genes linking cellular senescence and metabolic reprogramming in colorectal liver metastasis.

Συγγραφείς: Ma X; Department of General Surgery, Hepatobiliary Surgery Center, Huashan Hospital & Cancer Metastasis Institute, Fudan University, Shanghai, China., Chen L; Department of Hepatobiliary Cancer, Liver cancer research center, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Tianjin Key Laboratory of Digestive Cancer, Tianjin's Clinical Research Center for Cancer, Tianjin, China., Yi C; Department of General Surgery, Hepatobiliary Surgery Center, Huashan Hospital & Cancer Metastasis Institute, Fudan University, Shanghai, China., Li Y; Department of General Surgery, Hepatobiliary Surgery Center, Huashan Hospital & Cancer Metastasis Institute, Fudan University, Shanghai, China., Geng Y; Department of General Surgery, Hepatobiliary Surgery Center, Huashan Hospital & Cancer Metastasis Institute, Fudan University, Shanghai, China., Tao B; Department of General Surgery, Hepatobiliary Surgery Center, Huashan Hospital & Cancer Metastasis Institute, Fudan University, Shanghai, China., Chen J; Department of General Surgery, Hepatobiliary Surgery Center, Huashan Hospital & Cancer Metastasis Institute, Fudan University, Shanghai, China.

Πηγή: Bioscience trends [Biosci Trends] 2026 Jan 07; Vol. 19 (6), pp. 672-683. Date of Electronic Publication: 2025 Oct 31.

Τύπος έκδοσης: Journal Article

Στοιχεία περιοδικού: Publisher: International Research and Cooperation Association for Bio & Socio-Sciences Advancement Country of Publication: Japan NLM ID: 101502754 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1881-7823 (Electronic) Linking ISSN: 18817815 NLM ISO Abbreviation: Biosci Trends Subsets: MEDLINE

Ιατρικοί όροι (MeSH): Liver Neoplasms*/secondary , Liver Neoplasms*/genetics , Liver Neoplasms*/metabolism , Colorectal Neoplasms*/genetics , Colorectal Neoplasms*/pathology , Colorectal Neoplasms*/metabolism , DNA Methylation*/genetics , Cellular Senescence*/genetics , Cellular Reprogramming*/genetics, Chemokine CXCL1/genetics ; Plasminogen Activator Inhibitor 1/genetics ; Intracellular Signaling Peptides and Proteins/genetics ; Fluorouracil/pharmacology ; Fluorouracil/therapeutic use ; Biomarkers, Tumor/genetics ; Oxaliplatin/pharmacology ; Oxaliplatin/therapeutic use ; Humans ; Gene Expression Profiling ; Gene Expression Regulation, Neoplastic ; Transcriptome ; Epigenesis, Genetic ; Metabolic Reprogramming ; Cell Cycle Proteins ; N-myc Downstream-Regulated Gene 1 Protein

Remodeling of Mitochondrial Networks: Cellular Adaptation and Microenvironmental Reprogramming in Hematologic Malignancies.

Συγγραφείς: Li Y; Department of Hematology, Shandong Provincial Hospital, Cheeloo College of Medicine, Shandong University, Jinan, China., Hu X; Department of Hematology, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, China., Zhou X; Department of Hematology, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, China.; National Clinical Research Center for Hematologic Diseases, the First Affiliated Hospital of Soochow University, Suzhou, China.

Πηγή: Blood cancer discovery [Blood Cancer Discov] 2026 Mar 04; Vol. 7 (2), pp. 212-224.

Τύπος έκδοσης: Journal Article; Review

Στοιχεία περιοδικού: Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 101764786 Publication Model: Print Cited Medium: Internet ISSN: 2643-3249 (Electronic) Linking ISSN: 26433230 NLM ISO Abbreviation: Blood Cancer Discov Subsets: MEDLINE

Ιατρικοί όροι (MeSH): Hematologic Neoplasms*/metabolism , Hematologic Neoplasms*/pathology , Hematologic Neoplasms*/genetics , Mitochondria*/metabolism , Mitochondria*/pathology , Mitochondria*/genetics , Tumor Microenvironment* , Cellular Reprogramming*, Humans ; Animals ; Metabolic Reprogramming ; Mitophagy

Phospholipid remodeling interplays with auxin signaling to modulate cellular reprogramming in Arabidopsis regeneration.

Συγγραφείς: Chang P; Key Laboratory of Plant Molecular Physiology and State Key Laboratory of Forage Breeding-by-Design and Utilization, Institute of Botany, Chinese Academy of Sciences, China National Botanical Garden, Beijing 100093, China.; University of Chinese Academy of Sciences, Beijing 100049, China.; Henan Sesame Research Center, Henan Academy of Agricultural Sciences, Zhengzhou 450002, China., Yang X; Key Laboratory of Plant Molecular Physiology and State Key Laboratory of Forage Breeding-by-Design and Utilization, Institute of Botany, Chinese Academy of Sciences, China National Botanical Garden, Beijing 100093, China.; University of Chinese Academy of Sciences, Beijing 100049, China., Liu X; Key Laboratory of Plant Molecular Physiology and State Key Laboratory of Forage Breeding-by-Design and Utilization, Institute of Botany, Chinese Academy of Sciences, China National Botanical Garden, Beijing 100093, China.; University of Chinese Academy of Sciences, Beijing 100049, China., Guo S; Key Laboratory of Plant Molecular Physiology and State Key Laboratory of Forage Breeding-by-Design and Utilization, Institute of Botany, Chinese Academy of Sciences, China National Botanical Garden, Beijing 100093, China.; University of Chinese Academy of Sciences, Beijing 100049, China., Zhou J; Key Laboratory of Plant Molecular Physiology and State Key Laboratory of Forage Breeding-by-Design and Utilization, Institute of Botany, Chinese Academy of Sciences, China National Botanical Garden, Beijing 100093, China.; University of Chinese Academy of Sciences, Beijing 100049, China., He M; Key Laboratory of Plant Molecular Physiology and State Key Laboratory of Forage Breeding-by-Design and Utilization, Institute of Botany, Chinese Academy of Sciences, China National Botanical Garden, Beijing 100093, China.; University of Chinese Academy of Sciences, Beijing 100049, China., Li Z; Key Laboratory of Plant Molecular Physiology and State Key Laboratory of Forage Breeding-by-Design and Utilization, Institute of Botany, Chinese Academy of Sciences, China National Botanical Garden, Beijing 100093, China.; University of Chinese Academy of Sciences, Beijing 100049, China., Xu E; Key Laboratory of Plant Molecular Physiology and State Key Laboratory of Forage Breeding-by-Design and Utilization, Institute of Botany, Chinese Academy of Sciences, China National Botanical Garden, Beijing 100093, China., Xin W; Key Laboratory of Plant Molecular Physiology and State Key Laboratory of Forage Breeding-by-Design and Utilization, Institute of Botany, Chinese Academy of Sciences, China National Botanical Garden, Beijing 100093, China., Hu Y; Key Laboratory of Plant Molecular Physiology and State Key Laboratory of Forage Breeding-by-Design and Utilization, Institute of Botany, Chinese Academy of Sciences, China National Botanical Garden, Beijing 100093, China.; National Center for Plant Gene Research, Beijing 100093, China., Xu C; Key Laboratory of Plant Molecular Physiology and State Key Laboratory of Forage Breeding-by-Design and Utilization, Institute of Botany, Chinese Academy of Sciences, China National Botanical Garden, Beijing 100093, China.

Πηγή: The Plant cell [Plant Cell] 2026 Jun 02; Vol. 38 (6).

Τύπος έκδοσης: Journal Article

Στοιχεία περιοδικού: Publisher: Oxford University Press Country of Publication: England NLM ID: 9208688 Publication Model: Print Cited Medium: Internet ISSN: 1532-298X (Electronic) Linking ISSN: 10404651 NLM ISO Abbreviation: Plant Cell Subsets: MEDLINE

Ιατρικοί όροι (MeSH): Indoleacetic Acids*/metabolism , Indoleacetic Acids*/pharmacology , Arabidopsis*/physiology , Arabidopsis*/metabolism , Arabidopsis*/genetics , Regeneration*/physiology , Phospholipids*/metabolism , Cellular Reprogramming*, Arabidopsis Proteins/metabolism ; Arabidopsis Proteins/genetics ; Phosphatidic Acids/metabolism ; Plant Growth Regulators/metabolism ; Signal Transduction ; Gene Expression Regulation, Plant ; Plants, Genetically Modified

Reprogramming Induced Pluripotent Stem Cell Lines from Frozen Buffy Coat Samples.

Συγγραφείς: Art J; Center for Molecular Medicine, University of Georgia; Interdisciplinary Neuroscience, University of Georgia; js.esquibel@yahoo.com., James C; Center for Molecular Medicine, University of Georgia; Department of Biochemistry and Molecular Biology, University of Georgia., Dalal B; Center for Molecular Medicine, University of Georgia; Department of Biochemistry and Molecular Biology, University of Georgia., Fantone K; Department of Infectious Diseases, College of Veterinary Medicine, University of Georgia., Rada B; Department of Infectious Diseases, College of Veterinary Medicine, University of Georgia., Felner EI; Division of Pediatric Endocrinology, Emory University School of Medicine., Gonzalez-Duarte A; Dysautonomia Center, New York University Langone Health., Michopoulos V; Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine., Corneo B; Stem Cell Core, Columbia Stem Cell Initiative, Columbia University., Zeltner N; Center for Molecular Medicine, University of Georgia; Department of Biochemistry and Molecular Biology, University of Georgia; Department of Cellular Biology, University of Georgia.

Πηγή: Journal of visualized experiments : JoVE [J Vis Exp] 2026 Apr 10 (230). Date of Electronic Publication: 2026 Apr 10.

Τύπος έκδοσης: Journal Article; Video-Audio Media; Research Support, N.I.H., Extramural

Στοιχεία περιοδικού: Publisher: MYJoVE Corporation Country of Publication: United States NLM ID: 101313252 Publication Model: Electronic Cited Medium: Internet ISSN: 1940-087X (Electronic) Linking ISSN: 1940087X NLM ISO Abbreviation: J Vis Exp Subsets: MEDLINE

Ιατρικοί όροι (MeSH): Induced Pluripotent Stem Cells*/cytology , Blood Buffy Coat*/cytology , Cellular Reprogramming Techniques*/methods, Leukocytes, Mononuclear/cytology ; Humans ; Cryopreservation ; Cellular Reprogramming

Hepatocyte-specific partial cellular reprogramming via selective OSK mRNA lipid nanoparticle attenuates liver fibrosis.

Συγγραφείς: Zhang C; Human Phenome Institute, Fudan University, Shanghai 201203, China., Bai Y; Human Phenome Institute, Fudan University, Shanghai 201203, China., Yin Q; Human Phenome Institute, Fudan University, Shanghai 201203, China., Li J; Human Phenome Institute, Fudan University, Shanghai 201203, China., Huang K; Human Phenome Institute, Fudan University, Shanghai 201203, China., Qiu M; Human Phenome Institute, Fudan University, Shanghai 201203, China; Center for mRNA Translational Research, Fudan University, Shanghai 200438, China; Zhangjiang mRNA Innovation and Translation Center, Shanghai 201203, China. Electronic address: mqiu@fudan.edu.cn.

Πηγή: Journal of controlled release : official journal of the Controlled Release Society [J Control Release] 2026 Feb 10; Vol. 390, pp. 114569. Date of Electronic Publication: 2025 Dec 22.

Τύπος έκδοσης: Journal Article; Research Support, Non-U.S. Gov't

Στοιχεία περιοδικού: Publisher: Elsevier Science Publishers Country of Publication: Netherlands NLM ID: 8607908 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-4995 (Electronic) Linking ISSN: 01683659 NLM ISO Abbreviation: J Control Release Subsets: MEDLINE

Ιατρικοί όροι (MeSH): Nanoparticles*/administration & dosage , Nanoparticles*/chemistry , RNA, Messenger*/administration & dosage , Hepatocytes*/metabolism , Liver Cirrhosis*/therapy , Liver Cirrhosis*/genetics , Liver Cirrhosis*/pathology , Octamer Transcription Factor-3*/genetics , Lipids*/chemistry , Lipids*/administration & dosage , SOXB1 Transcription Factors*/genetics , Kruppel-Like Transcription Factors*/genetics , Cellular Reprogramming*, Animals ; Kruppel-Like Factor 4 ; Mice, Inbred C57BL ; Male ; Mice ; Humans ; Liposomes