Dissolving Microneedles Loaded with Lipid Nanocarriers for Vaginal Delivery of Clotrimazole: In Vitro and Ex Vivo Evaluation

Συγγραφείς: Udayakumar, Paarkavi, Author, Skalko-Basnet, Natasa, Author, Rondahl, Veronica, Author, Cotaquispe, Cristhian Fernando Salas, Author, Hemmingsen, Lisa Myrseth, Author, Sotiriou, Georgios A., Author, Du, Juan, Author, Teleki, Alexandra, Author

Συνεισφορές: Udayakumar, Paarkavi, Author, Skalko-Basnet, Natasa, Author, Rondahl, Veronica, Author, Cotaquispe, Cristhian Fernando Salas, Author, Hemmingsen, Lisa Myrseth, Author, Sotiriou, Georgios A., Author, Du, Juan, Author, Teleki, Alexandra, Author

Πηγή: Molecular Pharmaceutics. 23(4):2611-2625

Θεματικοί όροι: lipid-based formulation, liposome, poorly water-solubledrug, dissolvable microneedles, vaginal drug delivery

Περιγραφή αρχείου: electronic

Σύνδεσμος πρόσβασης: https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-588263
https://doi.org/10.1021/acs.molpharmaceut.5c01721

Low-Temperature Hot Melt Extrusion: Solid-State Organization and Mechanical Performance of Lipid Filaments

Συγγραφείς: Alva, Carolina^{aff1, aff2}, Hink, Michael^{aff1, aff2}, Doğan, Aygün^aff1, Afonso Urich, Jesús Alberto^aff1, Matić, Josip^aff1, Specht, Fabian^aff3, Freichel, Tanja^aff4, Reyer, Sebastian^aff4, Rillmann, Thomas^aff4, Abrahmsén-Alami, Susanna^aff5, Booth, Jonathan^aff6, Spoerk, Martin^{aff1, aff7}, Salar-Behzadi, Sharareh^{aff1, aff2}

Πηγή: Molecular Pharmaceutics. 23(7):3855-3870

Διαθεσιμότητα: https://pubs.acs.org/doi/10.1021/acs.molpharmaceut.6c00338

Double emulsions enable in situ generation of permeation enhancers for oral delivery of macromolecules

Συγγραφείς: Pohlit, Hannah, Author, Li, Lingxiao, Author, Bini, Estela Isabel, Author, Colucci, Dario, Author, Cotaquispe, Cristhian Fernando Salas, Author, Sikström, Maja, Author, Larsson, Per, Author, Bergström, Christel, 1973-, Author, Hossain, Shakhawath, Author, Brayden, David J., Author, Teleki, Alexandra, Author

Συνεισφορές: Pohlit, Hannah, Author, Li, Lingxiao, Author, Bini, Estela Isabel, Author, Colucci, Dario, Author, Cotaquispe, Cristhian Fernando Salas, Author, Sikström, Maja, Author, Larsson, Per, Author, Bergström, Christel, 1973-, Author, Hossain, Shakhawath, Author, Brayden, David J., Author, Teleki, Alexandra, Author

Πηγή: Science for Life Laboratory – a national resource center for high–throughput molecular bioscience Journal of Colloid and Interface Science. 724(Part 1)

Θεματικοί όροι: Lipid-based formulation, Lipolysis, Oral drug delivery, Molecular dynamics simulations, Intestinal permeability, Oral peptide delivery

Περιγραφή αρχείου: electronic

Σύνδεσμος πρόσβασης: https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-594733
https://doi.org/10.1016/j.jcis.2026.141012

Lyophilization of Curcumin-Loaded Lipodisks: pre-and post-processing evaluation of formulation characteristics

Συγγραφείς: Ali, Sajid, Author, Silva, Luís, Author, Gedda, Lars, Author, Eskner, Ebba, Author, Edwards, Katarina, Author

Συνεισφορές: Ali, Sajid, Author, Silva, Luís, Author, Gedda, Lars, Author, Eskner, Ebba, Author, Edwards, Katarina, Author

Πηγή: International Journal of Pharmaceutics. 693

Θεματικοί όροι: Freeze-drying, Lipodisks, Curcumin, Lipid-based formulation, Physicochemical properties, Drug delivery system

Περιγραφή αρχείου: electronic

Σύνδεσμος πρόσβασης: https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-582042
https://doi.org/10.1016/j.ijpharm.2026.126681

Integrative nanoparticulate strategies with SEDDS for controlled drug release: from lipid platforms to smart delivery systems

Συγγραφείς: Jin, Sung Giu^Aff1, Cho, Jung Hyun^{Aff2, IDs4000502500786y_cor1}, Choi, Han-Gon^{Aff3, IDs4000502500786y_cor2}

Πηγή: Journal of Pharmaceutical Investigation. 56(3):497-528

Novel Hybrid Polymer-Lipid-Based Formulations for Enhanced Dissolution Rates of Poorly Water-Soluble Drugs: A Quality by Design (QbD) Approach via Hot Melt Extrusion

Συγγραφείς: Kolipaka, Siva S.^Aff1, Junqueira, Laura A.^Aff5, Garg, Vivek^Aff4, Bhatt, Shaumil^Aff6, Trivedi, Vivek^Aff3, Douroumis, Dennis^{Aff2, Aff5, IDs12249026035303_cor1}

Πηγή: AAPS PharmSciTech: An Official Journal of the American Association of Pharmaceutical Scientists. 27(7)

Impact of Composition of Lipid-Based Formulations on First-Pass Drug Metabolism after Oral Administration

Συγγραφείς: Tanaka, Yusuke^aff1, Fukaishi, Rikuto^aff1, Okamoto, Daiki^aff1, Kurakazu, Takanori^aff2, Nakai, Tokio^aff2, Yagi, Haruya^aff1, Sakuma, Shinji^aff1

Πηγή: Molecular Pharmaceutics. 22(4):2098-2107

Διαθεσιμότητα: https://pubs.acs.org/doi/10.1021/acs.molpharmaceut.4c01299

Synergistic stabilization of emulsion gel by nanoparticles and surfactant enables 3D printing of lipid-rich solid oral dosage forms

Συγγραφείς: Johannesson, Jenny, 1990-, Author, Pathare, Malhar Manik, Author, Johansson, Mathias, Author, Bergström, Christel, 1973-, Author, Teleki, Alexandra, Author

Συνεισφορές: Johannesson, Jenny, 1990-, Author, Pathare, Malhar Manik, Author, Johansson, Mathias, Author, Bergström, Christel, 1973-, Author, Teleki, Alexandra, Author

Πηγή: Journal of Colloid and Interface Science. 650, part B:1253-1264

Θεματικοί όροι: Poorly water-soluble drug, Lipid-based formulation, Oil-in-water emulsion, Silica nanoparticle, Emulsion gel, Lipid digestion, Semi-solid extrusion, 3D printing

Περιγραφή αρχείου: electronic

Σύνδεσμος πρόσβασης: https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-510008
https://doi.org/10.1016/j.jcis.2023.07.055

In Vitro Digestion–In Situ Absorption Setup Employing a Physiologically Relevant Value of the Membrane Surface Area/Volume Ratio for Evaluating Performance of Lipid-Based Formulations: A Comparative Study with an In Vitro Digestion–Permeation Model

Συγγραφείς: Tanaka, Yusuke^aff1, Arai, Hinata^aff2, Hidaka, Aya^aff2, Noda, Saki^aff2, Imai, Ko^aff1, Tsujisawa, Fumiya^aff1, Yagi, Haruya^aff1, Sakuma, Shinji^aff1

Πηγή: Molecular Pharmaceutics. 21(7):3459-3470

Διαθεσιμότητα: https://pubs.acs.org/doi/10.1021/acs.molpharmaceut.4c00161

Rationalizing Counterion Selection for the Development of Lipophilic Salts: A Case Study with Venetoclax

Συγγραφείς: Ryan, Callum D.^{aff1, aff2}, Griffin, Brendan T.^{aff1, aff2}, O’Shea, Joseph P.^aff1

Πηγή: Molecular Pharmaceutics. 21(6):2981-2992

Διαθεσιμότητα: https://pubs.acs.org/doi/10.1021/acs.molpharmaceut.4c00106

Exploring the promises and challenges of cochleates for drug delivery applications

Συγγραφείς: Lee, Jisu^Aff1, Goo, Yoon Tae^Aff2, Shakhakarmi, Kanchan^Aff1, Kang, Myung Joo^Aff3, Lee, Sangkil^{Aff1, IDs40005025007555_cor1}

Πηγή: Journal of Pharmaceutical Investigation. 55(6):809-825

Enhancing the pharmacokinetics of abiraterone acetate through lipid-based formulations: addressing solubility and food effect challenges

Συγγραφείς: Taheri, Ali^Aff1, Almasri, Ruba^Aff1, Wignall, Anthony^Aff1, Schultz, Hayley B.^Aff1, Elz, Aurelia S.^Aff1, Ariaee, Amin^Aff1, Bremmell, Kristen E.^Aff1, Joyce, Paul^Aff1, Prestidge, Clive A.^{Aff1, IDs1334602401755y_cor1}

Πηγή: Drug Delivery and Translational Research: An Official Journal of the Controlled Release Society. 15(11):3770-3782

Using mixtures of linoleic acid, a long-chain polyunsaturated fatty acid, and its monoglyceride in lipid-based formulations to increase drug loading and enhance aqueous microemulsification

Συγγραφείς: Kandagatla, Hari P. ^a, Chowdhury, Nower ^a, Verbić, Tatjana Ž. ^b, Avdeef, Alex ^c, Savoy, Adélaïde ^d, Kuentz, Martin ^d, Serajuddin, Abu T.M ^{a, ⁎}

Πηγή: In International Journal of Pharmaceutics 5 October 2026 703

Effect of transcript length, temperature, and lyophilization on mRNA-lipid nanoparticle stability

Συγγραφείς: Chillara, Manasa ^{a, b, 1}, Zhao, Weibo ^{a, b, 1}, Dordick, Jonathan S. ^{a, b, ⁎}, Przybycien, Todd ^{a, b, ⁎}

Πηγή: In Journal of Pharmaceutical Sciences August 2026 115(8)

From Liquid to Solid: Formulation and Characterization of Testosterone-Loaded S-SMEDDS Pellets Using a 24 Factorial Design

Συγγραφείς: de Sousa Borges, Ohary^Aff1, Kramer, Julia Ornelas^Aff1, Pascoa, Henrique^Aff1, de Paula Santos, Yanka Machado^Aff1, Freitas, Leticia Silva Oliveira^Aff1, Lima, Eliana M.^Aff1, Silva, Luís Antônio Dantas^Aff1, Diniz, Danielle Guimarães A.^{Aff1, Aff2, IDs12249026033292_cor1}

Πηγή: AAPS PharmSciTech: An Official Journal of the American Association of Pharmaceutical Scientists. 27(3)

Formulation and In Vitro Evaluation of a Self-Emulsifying Drug Delivery System of Diclofenac Sodium

Συγγραφείς: Abhinandan Satapathy*, P. N. Tapaswini Behera, Sradhanjali Patra

Θεματικοί όροι: Diclofenac sodium, Self-emulsifying drug delivery system, SEDDS, Poorly water-soluble drugs, Bioavailability enhancement, Lipid-based formulation, In-vitro evaluation

Feed injection–enabled reversed phase liquid chromatography for simplified analysis of lipophilic drugs and formulations

Συγγραφείς: Foshag, Daniel ^a, Buckenmaier, Stephan ^a, Petersson, Patrik ^{b, ⁎}

Πηγή: In Journal of Chromatography A 10 May 2026 1774

Lipid-based coating of supersaturated amorphous solid dispersions: could it represent an approach to improving their physical stability or oral bioavailability?

Συγγραφείς: Huynh, Van-Trung-Tin ^a, Boniatti, Janine ^b, de Paiva Lacerda, Suênia ^a, Bernard, Maëla ^c, Denis, Sylvain ^d, Beyssac, Eric ^d, Ré, Maria-Inês ^{a, ⁎}

Πηγή: In Journal of Drug Delivery Science and Technology May 2026 119

Dissolution-microdialysis predicts oral bioavailability from phospholipid-based amorphous solid dispersions

Συγγραφείς: Paulus, Felix ^{a, c}, Tønning, Mikkel Højmark ^{a, c}, Bauer-Brandl, Annette ^a, Brandl, Martin ^{a, ⁎}, Jacobsen, Ann-Christin ^b

Πηγή: In Journal of Pharmaceutical Sciences May 2026 115(5)

Increasing Linker Chain Length and Intestinal Stability Enhances Lymphatic Transport and Lymph Node Exposure of Triglyceride Mimetic Prodrugs of a Model Immunomodulator Mycophenolic Acid

Συγγραφείς: Han, Sifei^aff1d1, Quach, Tim^{aff1d2, aff2}, Hu, Luojuan^aff1d1, Lim, Shea Fern^aff1d2, Zheng, Dan^aff1d1, Leong, Nathania J.^aff1d1, Sharma, Garima^aff1d1, Bonner, Daniel^aff2, Simpson, Jamie S.^{aff1d2, aff2}, Trevaskis, Natalie L.^aff1d1, Porter, Christopher J.H.^aff1d1

Πηγή: Molecular Pharmaceutics. 20(5):2675-2685

Διαθεσιμότητα: https://pubs.acs.org/doi/10.1021/acs.molpharmaceut.3c00099