Massively Parallel, Single-Molecule Assessment of Synthetic Fidelity and Drug-Like Properties in a DNA-Encoded Library.

Συγγραφείς: Koch G; Address: Department of Chemistry and Biochemistry, University of California, Santa Cruz; 1156 High Street, Santa Cruz, California95064, United States., Lawler MF; Address: Anagenex, 20 Maguire Rd Suite 302, Lexington, Massachusetts02421, United States., Murray A; Address: Department of Chemistry and Biochemistry, University of California, Santa Cruz; 1156 High Street, Santa Cruz, California95064, United States., Carlson N; Address: Anagenex, 20 Maguire Rd Suite 302, Lexington, Massachusetts02421, United States., Engstrom A; Address: Department of Chemistry and Biochemistry, University of California, Santa Cruz; 1156 High Street, Santa Cruz, California95064, United States., Zhang P; Address: Department of Chemistry and Biochemistry, University of California, Santa Cruz; 1156 High Street, Santa Cruz, California95064, United States., Steiner M; Address: Department of Chemistry and Biochemistry, University of California, Santa Cruz; 1156 High Street, Santa Cruz, California95064, United States., Avila SB; Address: Department of Chemistry and Biochemistry, University of California, Santa Cruz; 1156 High Street, Santa Cruz, California95064, United States., Cloutier-Leblanc K; Address: Anagenex, 20 Maguire Rd Suite 302, Lexington, Massachusetts02421, United States., Leelananda S; Address: Anagenex, 20 Maguire Rd Suite 302, Lexington, Massachusetts02421, United States., Grady LC; Address: Anagenex, 20 Maguire Rd Suite 302, Lexington, Massachusetts02421, United States., Taechalertpaisarn J; Address: Department of Chemistry and Biochemistry, University of California, Santa Cruz; 1156 High Street, Santa Cruz, California95064, United States., Corcoran C; Address: Department of Chemistry and Biochemistry, University of California, Santa Cruz; 1156 High Street, Santa Cruz, California95064, United States., Tilmans N; Address: Anagenex, 20 Maguire Rd Suite 302, Lexington, Massachusetts02421, United States., Lokey RS; Address: Department of Chemistry and Biochemistry, University of California, Santa Cruz; 1156 High Street, Santa Cruz, California95064, United States.

Πηγή: Journal of medicinal chemistry [J Med Chem] 2026 Aug 13; Vol. 69 (15), pp. 19390-19401.

Τύπος έκδοσης: Journal Article

Στοιχεία περιοδικού: Publisher: American Chemical Society Country of Publication: United States NLM ID: 9716531 Publication Model: Print Cited Medium: Internet ISSN: 1520-4804 (Electronic) Linking ISSN: 00222623 NLM ISO Abbreviation: J Med Chem Subsets: MEDLINE

Ιατρικοί όροι (MeSH): DNA*/chemistry , Small Molecule Libraries*/chemistry , Gene Library*, Drug Discovery/methods ; Peptide Library ; Hydrophobic and Hydrophilic Interactions ; Chromatography, Liquid

Combining Yeast Display and Bacterial Genomic Library for the Unbiased Isolation of Novel Polysaccharide-Binding Peptides.

Συγγραφείς: Stabile A; Department of Life Sciences, University of Trieste, Via L. Giorgieri 5, 34127 Trieste, Italy., Scaramella G; Department of Life Sciences, University of Trieste, Via L. Giorgieri 5, 34127 Trieste, Italy., Puccio S; Laboratory of Translational Immunology, Istituto di Ricovero e Cura a Carattere Scientifico Humanitas Research Hospital, Via Manzoni 56, 20089 Rozzano, Italy.; Institute of Genetic and Biomedical Research, National Research Council, Via Manzoni 113, 20089 Rozzano, Italy., Brady J; Food Science Department, Cornell University, 101A Stocking Hall, Ithaca, NY 14853, USA., Goltermann L; Costerton Biofilm Center, Department of Immunology and Microbiology, University of Copenhagen, Blegdamsvej 3B, DK-2200 Copenhagen, Denmark., Tolker-Nielsen T; Costerton Biofilm Center, Department of Immunology and Microbiology, University of Copenhagen, Blegdamsvej 3B, DK-2200 Copenhagen, Denmark., Bellich B; Institute for Maternal and Child Health, Istituto di Ricovero e Cura a Carattere Scientifico 'Burlo Garofolo', Via dell'Istria 65/1, 34137 Trieste, Italy., De Zotti S; Department of Life Sciences, University of Trieste, Via L. Giorgieri 5, 34127 Trieste, Italy., Lagatolla C; Department of Life Sciences, University of Trieste, Via L. Giorgieri 5, 34127 Trieste, Italy., Ferrara F; Specifica Inc., an IQVIA Laboratories Company, Santa Fe, NM 87501, USA., Rizzo R; Department of Life Sciences, University of Trieste, Via L. Giorgieri 5, 34127 Trieste, Italy., Cescutti P; Department of Life Sciences, University of Trieste, Via L. Giorgieri 5, 34127 Trieste, Italy., Sblattero D; Department of Life Sciences, University of Trieste, Via L. Giorgieri 5, 34127 Trieste, Italy.

Πηγή: International journal of molecular sciences [Int J Mol Sci] 2026 Mar 06; Vol. 27 (5). Date of Electronic Publication: 2026 Mar 06.

Τύπος έκδοσης: Journal Article

Στοιχεία περιοδικού: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067 (Electronic) Linking ISSN: 14220067 NLM ISO Abbreviation: Int J Mol Sci Subsets: MEDLINE

Ιατρικοί όροι (MeSH): Peptides*/metabolism , Peptides*/chemistry , Peptides*/isolation & purification , Peptides*/genetics , Peptides*/pharmacology , Burkholderia*/genetics , Burkholderia*/metabolism , Polysaccharides*/metabolism , Saccharomyces cerevisiae*/genetics , Saccharomyces cerevisiae*/metabolism , Genomic Library* , Genome, Bacterial*, Biofilms/drug effects ; Biofilms/growth & development ; Protein Binding ; Cell Surface Display Techniques ; Peptide Library

Bridging Psychosocial Service Gaps in Rural Communities through Library Social Work.

Συγγραφείς: Hong M; Michin Hong, PhD, is associate professor, School of Social Work, Indiana University, 902 West New York Street, Indianapolis, IN 46202, USA., Yoon A; Ayoung Yoon, PhD, is associate professor, Luddy School of Informatics, Computing, and Engineering, Indiana University, Indianapolis, IN, USA., Andricus H; Hutcherson Andricus, MSW, is doctoral student, School of Social Work, Indiana University, Indianapolis, IN, USA., Kohl K; Karen Kohl, BS, is research assistant and MLIS student, Indiana University, Indianapolis, IN, USA.

Πηγή: Social work [Soc Work] 2026 Oct 01; Vol. 71 (4), pp. 347-356.

Τύπος έκδοσης: Journal Article

Στοιχεία περιοδικού: Publisher: Oxford University Press Country of Publication: United States NLM ID: 2984852R Publication Model: Print Cited Medium: Internet ISSN: 1545-6846 (Electronic) Linking ISSN: 00378046 NLM ISO Abbreviation: Soc Work Subsets: MEDLINE

Ιατρικοί όροι (MeSH): Social Work*/organization & administration , Social Work*/methods , Library Services*/organization & administration , Rural Population*, Librarians/psychology ; Humans ; Male ; Female ; Adult ; Middle Aged

IMPACT OF FLUORESCENT DYES ON MUTATIONS IN NEXT GENERATION SEQUENCING LIBRARY GENERATION.

Συγγραφείς: Butty V; Biology Massachusetts Institute of Technology.; Biological Engineering Massachusetts Institute of Technology.; Koch Institute for Integrative Cancer Research Massachusetts Institute of Technology., Patel P; NA n6TEC., Green S; Genomics and Microbiome Core Facility Rush University Medical Center., Levine S; Biology Massachusetts Institute of Technology.; Biological Engineering Massachusetts Institute of Technology.; Koch Institute for Integrative Cancer Research Massachusetts Institute of Technology.

Πηγή: Journal of biomolecular techniques : JBT [J Biomol Tech] 2026 Sep 01; Vol. 37 (3), pp. 51-59. Date of Electronic Publication: 2026 Sep 01 (Print Publication: 2026).

Τύπος έκδοσης: Journal Article

Στοιχεία περιοδικού: Publisher: Association of Biomolecular Resource Facilities Country of Publication: United States NLM ID: 100888641 Publication Model: eCollection Cited Medium: Internet ISSN: 1943-4731 (Electronic) Linking ISSN: 15240215 NLM ISO Abbreviation: J Biomol Tech Subsets: MEDLINE

Ιατρικοί όροι (MeSH): Fluorescent Dyes*/chemistry , High-Throughput Nucleotide Sequencing*/methods , Mutation* , Gene Library*, DNA Mutational Analysis/methods ; Polymerase Chain Reaction

Barcoded mutant library enables high-throughput functional genomics in a filamentous fungus.

Συγγραφείς: Huberman LB; Plant Pathology and Plant-Microbe Biology Section, School of Integrative Plant Science, Cornell University, Ithaca, NY 14853.; Department of Plant and Microbial Biology, University of California Berkeley, Berkeley, CA 94720., Villalobos-Escobedo JM; Department of Plant and Microbial Biology, University of California Berkeley, Berkeley, CA 94720.; Environmental Genomics and Systems Biology Division/Biosciences Area, Lawrence Berkeley National Laboratory, Berkeley, CA 94720.; Tecnologico de Monterrey, Institute for Obesity Research, Monterrey, NL 64700, México., Skerker JM; Department of Bioengineering, University of California Berkeley, Berkeley, CA 94720., Shi R; Department of Plant and Microbial Biology, University of California Berkeley, Berkeley, CA 94720., Rico-Ramírez AM; Department of Plant and Microbial Biology, University of California Berkeley, Berkeley, CA 94720., Adams CA; Department of Plant and Microbial Biology, University of California Berkeley, Berkeley, CA 94720.; Environmental Genomics and Systems Biology Division/Biosciences Area, Lawrence Berkeley National Laboratory, Berkeley, CA 94720., Arkin AP; Environmental Genomics and Systems Biology Division/Biosciences Area, Lawrence Berkeley National Laboratory, Berkeley, CA 94720.; Department of Bioengineering, University of California Berkeley, Berkeley, CA 94720., Deutschbauer AM; Department of Plant and Microbial Biology, University of California Berkeley, Berkeley, CA 94720.; Environmental Genomics and Systems Biology Division/Biosciences Area, Lawrence Berkeley National Laboratory, Berkeley, CA 94720., Glass NL; Department of Plant and Microbial Biology, University of California Berkeley, Berkeley, CA 94720.; Environmental Genomics and Systems Biology Division/Biosciences Area, Lawrence Berkeley National Laboratory, Berkeley, CA 94720.

Πηγή: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2026 Sep; Vol. 123 (35), pp. e2616888123. Date of Electronic Publication: 2026 Aug 25.

Τύπος έκδοσης: Journal Article

Στοιχεία περιοδικού: Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1091-6490 (Electronic) Linking ISSN: 00278424 NLM ISO Abbreviation: Proc Natl Acad Sci U S A Subsets: MEDLINE

Ιατρικοί όροι (MeSH): Genomics*/methods , Trichoderma*/genetics , Fungi*/genetics , Gene Library* , Mutation*, Agrobacterium tumefaciens/genetics ; Genome, Fungal ; Mutagenesis, Insertional

A simple and rapid library preparation for Oxford nanopore amplicon sequencing using reverse complement PCR.

Συγγραφείς: Sonoda S; National Research Institute of Police Science, 6-3-1 Kashiwanoha, Kashiwa City, Chiba, 277-0882, Japan. Electronic address: sonoda@nrips.go.jp., Watanabe D; National Research Institute of Police Science, 6-3-1 Kashiwanoha, Kashiwa City, Chiba, 277-0882, Japan.

Πηγή: Analytical biochemistry [Anal Biochem] 2026 Sep; Vol. 716, pp. 116163. Date of Electronic Publication: 2026 May 27.

Τύπος έκδοσης: Journal Article

Στοιχεία περιοδικού: Publisher: Elsevier Country of Publication: United States NLM ID: 0370535 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1096-0309 (Electronic) Linking ISSN: 00032697 NLM ISO Abbreviation: Anal Biochem Subsets: MEDLINE

Ιατρικοί όροι (MeSH): Polymerase Chain Reaction*/methods , Nanopore Sequencing*/methods , Sequence Analysis, DNA*/methods , Gene Library* , Nanopores*, DNA Primers

Analysis and Annotation of c-Type Ions in Peptide Mass Spectral Libraries.

Συγγραφείς: Burke MC; Mass Spectrometry Data Center, Biomolecular Measurement Division, National Institute of Standards and Technology, Gaithersburg, Maryland20899, United States., Yang X; Mass Spectrometry Data Center, Biomolecular Measurement Division, National Institute of Standards and Technology, Gaithersburg, Maryland20899, United States., Liang Y; Mass Spectrometry Data Center, Biomolecular Measurement Division, National Institute of Standards and Technology, Gaithersburg, Maryland20899, United States., Neta P; Mass Spectrometry Data Center, Biomolecular Measurement Division, National Institute of Standards and Technology, Gaithersburg, Maryland20899, United States., Stein SE; Mass Spectrometry Data Center, Biomolecular Measurement Division, National Institute of Standards and Technology, Gaithersburg, Maryland20899, United States.

Πηγή: Journal of proteome research [J Proteome Res] 2026 Aug 07; Vol. 25 (8), pp. 4315-4321.

Τύπος έκδοσης: Journal Article

Στοιχεία περιοδικού: Publisher: American Chemical Society Country of Publication: United States NLM ID: 101128775 Publication Model: Print Cited Medium: Internet ISSN: 1535-3907 (Electronic) Linking ISSN: 15353893 NLM ISO Abbreviation: J Proteome Res Subsets: MEDLINE

Ιατρικοί όροι (MeSH): Peptides*/chemistry , Peptides*/analysis , Proteomics*/methods , Peptide Library*, Ions/chemistry ; Tandem Mass Spectrometry/methods ; Humans ; Amino Acid Sequence

Rapid Detection of Hemoglobinopathy Variants Using One-Step Library Preparation and Nanopore Sequencing.

Συγγραφείς: Yang X; Department of Institute of Antibody Engineering, School of Laboratory Medicine and Biotechnology, Southern Medical University, Guangzhou, China.; Guangzhou Darui Biotechnology Co., Ltd, Guangzhou, China., Yi S; Department of Guangxi Clinical Medical Research Center for Birth Defects, Guangxi Key Laboratory of Reproductive Health and Birth Defects Prevention and Control, Guangxi Zhuang Autonomous Region Women and Children Care Hospital, Nanning, China., Wei X; Fetal Medicine and Prenatal Diagnosis Department, Zhujiang Hospital, Southern Medical University, Guangzhou, China., Zheng G; Fetal Medicine and Prenatal Diagnosis Department, Zhujiang Hospital, Southern Medical University, Guangzhou, China., Wu L; Guangzhou Darui Biotechnology Co., Ltd, Guangzhou, China., Zhang L; Guangzhou Darui Biotechnology Co., Ltd, Guangzhou, China., Ouyang G; Guangzhou Darui Biotechnology Co., Ltd, Guangzhou, China., He S; Department of Guangxi Clinical Medical Research Center for Birth Defects, Guangxi Key Laboratory of Reproductive Health and Birth Defects Prevention and Control, Guangxi Zhuang Autonomous Region Women and Children Care Hospital, Nanning, China., Yang X; Department of Institute of Antibody Engineering, School of Laboratory Medicine and Biotechnology, Southern Medical University, Guangzhou, China., Yang F; Fetal Medicine and Prenatal Diagnosis Department, Zhujiang Hospital, Southern Medical University, Guangzhou, China.

Πηγή: Clinical chemistry [Clin Chem] 2026 Oct 05; Vol. 72 (10), pp. 1079-1092.

Τύπος έκδοσης: Journal Article

Στοιχεία περιοδικού: Publisher: Oxford University Press Country of Publication: England NLM ID: 9421549 Publication Model: Print Cited Medium: Internet ISSN: 1530-8561 (Electronic) Linking ISSN: 00099147 NLM ISO Abbreviation: Clin Chem Subsets: MEDLINE

Ιατρικοί όροι (MeSH): Hemoglobinopathies*/genetics , Hemoglobinopathies*/diagnosis , Nanopore Sequencing*/methods , Gene Library*, beta-Globins/genetics ; Humans ; Retrospective Studies ; Genetic Variation

Comparing the Performance of Double-Stranded and Single-Stranded DNA Libraries for Ancient Oral Microbiome Reconstruction.

Συγγραφείς: Burge K; Department of Anthropology, Harvard University, Cambridge, Massachusetts, USA., Velsko IM; Department of Archaeogenetics, Max Planck Institute for Evolutionary Anthropology, Leipzig, Germany.; Associated Research Group of Archaeogenetics, Leibniz Institute for Natural Product Research and Infection Biology, Hans Knöll Institute, Jena, Germany., Salazar-García DC; Departament de Prehistòria, Arqueologia i Història Antiga, Universitat de València, València, Spain.; Department of Geological Sciences, University of Cape Town, Cape Town, South Africa., Uriarte MH; Departamento de Prehistoria, Arqueología, Historia Antigua, Historia Medieval y Ciencias y Técnicas Historiográficas, Universidad de Murcia, Murcia, Spain., Lomba Maurandi J; Departamento de Prehistoria, Arqueología, Historia Antigua, Historia Medieval y Ciencias y Técnicas Historiográficas, Universidad de Murcia, Murcia, Spain., Warinner C; Department of Anthropology, Harvard University, Cambridge, Massachusetts, USA.; Department of Archaeogenetics, Max Planck Institute for Evolutionary Anthropology, Leipzig, Germany.; Associated Research Group of Archaeogenetics, Leibniz Institute for Natural Product Research and Infection Biology, Hans Knöll Institute, Jena, Germany.; Faculty of Biological Sciences, Friedrich Schiller University, Jena, Germany.; Department of Human Evolutionary Biology, Harvard University, Cambridge, Massachusetts, USA.

Πηγή: Molecular ecology resources [Mol Ecol Resour] 2026 Oct; Vol. 26 (7), pp. e70201.

Τύπος έκδοσης: Journal Article; Comparative Study; Evaluation Study

Στοιχεία περιοδικού: Publisher: Blackwell Country of Publication: England NLM ID: 101465604 Publication Model: Print Cited Medium: Internet ISSN: 1755-0998 (Electronic) Linking ISSN: 1755098X NLM ISO Abbreviation: Mol Ecol Resour Subsets: MEDLINE

Ιατρικοί όροι (MeSH): Mouth*/microbiology , Metagenomics*/methods , Microbiota* , Gene Library* , DNA, Ancient*, DNA, Single-Stranded/genetics ; Animals ; Humans ; Sequence Analysis, DNA ; Neanderthals

Sequence Inversion Dictates the Antiproliferative Activity of Bidirectional Tryptophan-Containing Dipeptide Libraries.

Συγγραφείς: Díaz JB; BioLab, Instituto Universitario de Bio-Orgánica Antonio González, Universidad de La Laguna, La Laguna, Spain., Khan AN; BioLab, Instituto Universitario de Bio-Orgánica Antonio González, Universidad de La Laguna, La Laguna, Spain., González-Bakker A; BioLab, Instituto Universitario de Bio-Orgánica Antonio González, Universidad de La Laguna, La Laguna, Spain., Padrón JM; BioLab, Instituto Universitario de Bio-Orgánica Antonio González, Universidad de La Laguna, La Laguna, Spain.

Πηγή: Journal of peptide science : an official publication of the European Peptide Society [J Pept Sci] 2026 Oct; Vol. 32 (10), pp. e70128.

Τύπος έκδοσης: Journal Article

Στοιχεία περιοδικού: Publisher: John Wiley & Sons Country of Publication: England NLM ID: 9506309 Publication Model: Print Cited Medium: Internet ISSN: 1099-1387 (Electronic) Linking ISSN: 10752617 NLM ISO Abbreviation: J Pept Sci Subsets: MEDLINE

Ιατρικοί όροι (MeSH): Dipeptides*/chemistry , Dipeptides*/pharmacology , Dipeptides*/chemical synthesis , Tryptophan*/chemistry , Tryptophan*/pharmacology , Antineoplastic Agents*/pharmacology , Antineoplastic Agents*/chemistry , Antineoplastic Agents*/chemical synthesis , Peptide Library*, Cell Proliferation/drug effects ; Humans ; Structure-Activity Relationship ; Drug Screening Assays, Antitumor ; Cell Line, Tumor

Discovery and characterization of a novel GH6 multifunctional enzyme from soil metagenomic library.

Συγγραφείς: Lyu Y; Anhui Vocational College of Grain Engineering, Hefei, 230011, China; College of Food Science and Technology, Nanjing Agricultural University, Nanjing, 210095, China; Sanya Research Lnstitute of Nanjing Agricultural University, Nanjing Agricultural University, Sanya, 572025, China., Wu S; Anhui Vocational College of Grain Engineering, Hefei, 230011, China., Fan X; College of Food Science and Technology, Nanjing Agricultural University, Nanjing, 210095, China., Zhang Y; College of Food Science and Technology, Nanjing Agricultural University, Nanjing, 210095, China., Zhang Q; College of Food Science and Technology, Nanjing Agricultural University, Nanjing, 210095, China., Wang S; College of Food Science and Technology, Nanjing Agricultural University, Nanjing, 210095, China., Feng Z; Anhui Vocational College of Grain Engineering, Hefei, 230011, China; College of Food Science and Technology, Nanjing Agricultural University, Nanjing, 210095, China. Electronic address: zfeng@njau.edu.cn.

Πηγή: Carbohydrate research [Carbohydr Res] 2026 Oct; Vol. 568, pp. 110046. Date of Electronic Publication: 2026 Jul 16.

Τύπος έκδοσης: Journal Article

Στοιχεία περιοδικού: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 0043535 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-426X (Electronic) Linking ISSN: 00086215 NLM ISO Abbreviation: Carbohydr Res Subsets: MEDLINE

Ιατρικοί όροι (MeSH): Soil Microbiology* , Metagenome* , Metagenomics* , Gene Library*, Recombinant Proteins/metabolism ; Recombinant Proteins/genetics ; Recombinant Proteins/chemistry ; Substrate Specificity ; Kinetics ; Amino Acid Sequence ; Enzyme Stability ; Cloning, Molecular

De Novo Discovery of Bioactive Cyclic Peptides via Cellular Selection of Genetically Encoded Libraries.

Συγγραφείς: Yang L; Department of Chemistry, University of Wisconsin-Madison, Madison, Wisconsin, USA., Behera A; Department of Biochemistry, University of Wisconsin-Madison, Madison, Wisconsin, USA., Meyers HJ; Department of Biochemistry, University of Wisconsin-Madison, Madison, Wisconsin, USA., Wang T; Department of Chemistry, University of Wisconsin-Madison, Madison, Wisconsin, USA.; Department of Biochemistry, University of Wisconsin-Madison, Madison, Wisconsin, USA.

Πηγή: Chembiochem : a European journal of chemical biology [Chembiochem] 2026 Sep 28; Vol. 27 (18), pp. e70532.

Τύπος έκδοσης: Journal Article; Review

Στοιχεία περιοδικού: Publisher: Wiley-VCH Verlag Country of Publication: Germany NLM ID: 100937360 Publication Model: Print Cited Medium: Internet ISSN: 1439-7633 (Electronic) Linking ISSN: 14394227 NLM ISO Abbreviation: Chembiochem Subsets: MEDLINE

Ιατρικοί όροι (MeSH): Peptides, Cyclic*/genetics , Peptides, Cyclic*/chemistry , Peptides, Cyclic*/pharmacology , Peptides, Cyclic*/metabolism , Drug Discovery*/methods , Peptide Library*, Humans ; Animals

A trainable language model with potential to modulate translation rates in non-model organisms by generating upstream untranslated region sequence libraries.

Συγγραφείς: Duggan AD; Department of Chemical and Physical Sciences, University of Toronto Mississauga, Mississauga, Ontario, Canada.; Department of Cell and Systems Biology, University of Toronto, Toronto, Ontario, Canada., Newman MP; Department of Chemical and Physical Sciences, University of Toronto Mississauga, Mississauga, Ontario, Canada.; Department of Chemistry, University of Toronto, Toronto, Ontario, Canada., McMillen DR; Department of Chemical and Physical Sciences, University of Toronto Mississauga, Mississauga, Ontario, Canada.; Department of Cell and Systems Biology, University of Toronto, Toronto, Ontario, Canada.; Department of Chemistry, University of Toronto, Toronto, Ontario, Canada.

Πηγή: PloS one [PLoS One] 2026 Sep 17; Vol. 21 (9), pp. e0348455. Date of Electronic Publication: 2026 Sep 17 (Print Publication: 2026).

Τύπος έκδοσης: Journal Article

Στοιχεία περιοδικού: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS One Subsets: MEDLINE

Ιατρικοί όροι (MeSH): 5' Untranslated Regions*/genetics , Protein Biosynthesis* , Gene Library* , Models, Genetic*, Escherichia coli/genetics ; Large Language Models ; Base Sequence

A novel one-step multiplex PCR method (OS-MPCR) for efficient NGS library preparation in cancer.

Συγγραφείς: Feng H; Department of Pathology, Zibo First Hospital, Zibo, Shandong, China., Hu X; Department of Pathology, Zibo First Hospital, Zibo, Shandong, China., Zhang L; Department of Pathology, Zibo First Hospital, Zibo, Shandong, China., Zhang Q; Department of Pathology, Zibo First Hospital, Zibo, Shandong, China., Wang S; Shanghai Yijian Health Technology Co., Ltd., Shanghai, China., Lv B; Shanghai Yijian Health Technology Co., Ltd., Shanghai, China., Zhang Y; Shanghai Yijian Health Technology Co., Ltd., Shanghai, China., Shi D; Shanghai Yijian Health Technology Co., Ltd., Shanghai, China., Zhou P; Department of Pathology, Zibo First Hospital, Zibo, Shandong, China.

Πηγή: PloS one [PLoS One] 2026 Sep 15; Vol. 21 (9), pp. e0357776. Date of Electronic Publication: 2026 Sep 15 (Print Publication: 2026).

Τύπος έκδοσης: Journal Article

Στοιχεία περιοδικού: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS One Subsets: MEDLINE

Ιατρικοί όροι (MeSH): Multiplex Polymerase Chain Reaction*/methods , High-Throughput Nucleotide Sequencing*/methods , Lung Neoplasms*/genetics , Gene Library*, Humans

Systematic Evaluation of On-DNA Nitro Reduction Reactions in Short and Elongated DNA Tags for DNA-Encoded Library Construction.

Συγγραφείς: Suh Y; Therapeutics & Biotechnology Division, Korea Research Institute of Chemical Technology, Daejeon34114, Republic of Korea.; Medicinal Chemistry & Pharmacology, University of Science & Technology, Daejeon34113, Republic of Korea., Cho KJ; Therapeutics & Biotechnology Division, Korea Research Institute of Chemical Technology, Daejeon34114, Republic of Korea., Kim HJ; Therapeutics & Biotechnology Division, Korea Research Institute of Chemical Technology, Daejeon34114, Republic of Korea.; Medicinal Chemistry & Pharmacology, University of Science & Technology, Daejeon34113, Republic of Korea., Jeon H; Therapeutics & Biotechnology Division, Korea Research Institute of Chemical Technology, Daejeon34114, Republic of Korea.; Medicinal Chemistry & Pharmacology, University of Science & Technology, Daejeon34113, Republic of Korea.

Πηγή: The Journal of organic chemistry [J Org Chem] 2026 Sep 04; Vol. 91 (35), pp. 11916-11922.

Τύπος έκδοσης: Journal Article

Στοιχεία περιοδικού: Publisher: American Chemical Society Country of Publication: United States NLM ID: 2985193R Publication Model: Print Cited Medium: Internet ISSN: 1520-6904 (Electronic) Linking ISSN: 00223263 NLM ISO Abbreviation: J Org Chem Subsets: MEDLINE

Ιατρικοί όροι (MeSH): DNA*/chemistry , Nitro Compounds*/chemistry , Gene Library*, Oxidation-Reduction

Light-Mediated Desulfurization of Peptides in Multi-Well Format for Combinatorial Library Synthesis.

Συγγραφείς: Jacobsen EA; Gubra, 2970 Hørsholm, Denmark.; Department of Chemistry, Technical University of Denmark, 2800 Kongens Lyngby, Denmark., Lava J; Department of Chemistry, Technical University of Denmark, 2800 Kongens Lyngby, Denmark., Thorseth A; Department of Electrical and Photonics Engineering, Technical University of Denmark, 2800 Kongens Lyngby, Denmark., Corell DD; Department of Electrical and Photonics Engineering, Technical University of Denmark, 2800 Kongens Lyngby, Denmark., Dam-Hansen C; Department of Electrical and Photonics Engineering, Technical University of Denmark, 2800 Kongens Lyngby, Denmark., Gotfredsen CH; Department of Chemistry, Technical University of Denmark, 2800 Kongens Lyngby, Denmark., Kræmer M; Gubra, 2970 Hørsholm, Denmark., Tran P; Gubra, 2970 Hørsholm, Denmark., Qvortrup K; Department of Chemistry, Technical University of Denmark, 2800 Kongens Lyngby, Denmark.

Πηγή: Molecules (Basel, Switzerland) [Molecules] 2026 Sep 03; Vol. 31 (17). Date of Electronic Publication: 2026 Sep 03.

Τύπος έκδοσης: Journal Article

Στοιχεία περιοδικού: Publisher: MDPI Country of Publication: Switzerland NLM ID: 100964009 Publication Model: Electronic Cited Medium: Internet ISSN: 1420-3049 (Electronic) Linking ISSN: 14203049 NLM ISO Abbreviation: Molecules Subsets: MEDLINE

Ιατρικοί όροι (MeSH): Peptides*/chemistry , Peptides*/chemical synthesis , Combinatorial Chemistry Techniques*/methods , Peptide Library* , Light*, Phosphines/chemistry ; Cysteine/chemistry ; Ultraviolet Rays

Optimizing phage elution for biopanning of plastic materials.

Συγγραφείς: Lyngsø NM; Interdisciplinary Nanoscience Center, Aarhus University, Gustav Wieds Vej 14, Aarhus, 8000, Denmark., Otzen DE; Interdisciplinary Nanoscience Center, Aarhus University, Gustav Wieds Vej 14, Aarhus, 8000, Denmark. Electronic address: dao@inano.au.dk.

Πηγή: Biochemical and biophysical research communications [Biochem Biophys Res Commun] 2026 Sep 03; Vol. 829, pp. 154187. Date of Electronic Publication: 2026 Jun 22.

Τύπος έκδοσης: Journal Article

Στοιχεία περιοδικού: Publisher: Elsevier Country of Publication: United States NLM ID: 0372516 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1090-2104 (Electronic) Linking ISSN: 0006291X NLM ISO Abbreviation: Biochem Biophys Res Commun Subsets: MEDLINE

Ιατρικοί όροι (MeSH): Plastics*/chemistry , Peptides*/chemistry , Peptides*/isolation & purification , Peptide Library* , Bacteriophages*, Surface-Active Agents/chemistry ; Ethanol/chemistry ; Hydrogen-Ion Concentration

Discovery and engineering of cold-active lipases facilitating the biodegradation of poly(ε-caprolactone) and polyurethane from the functional mixed genomic library.

Συγγραφείς: Jeong C; Division of Life Sciences, Korea Polar Research Institute, Incheon, 21990, South Korea; Department of Polar Sciences, University of Science and Technology, Incheon, 21990, South Korea., Yu SH; Division of Life Sciences, Korea Polar Research Institute, Incheon, 21990, South Korea; Department of Polar Sciences, University of Science and Technology, Incheon, 21990, South Korea., Won SJ; Division of Life Sciences, Korea Polar Research Institute, Incheon, 21990, South Korea., Kim JH; Division of Life Sciences, Korea Polar Research Institute, Incheon, 21990, South Korea., Choi W; Division of Life Sciences, Korea Polar Research Institute, Incheon, 21990, South Korea., Lee YM; Division of Life Sciences, Korea Polar Research Institute, Incheon, 21990, South Korea., Shin SC; Division of Life Sciences, Korea Polar Research Institute, Incheon, 21990, South Korea., Kim HW; Division of Life Sciences, Korea Polar Research Institute, Incheon, 21990, South Korea; Department of Polar Sciences, University of Science and Technology, Incheon, 21990, South Korea. Electronic address: hwkim@kopri.re.kr.

Πηγή: International journal of biological macromolecules [Int J Biol Macromol] 2026 Sep; Vol. 374, pp. 153331. Date of Electronic Publication: 2026 Jul 03.

Τύπος έκδοσης: Journal Article

Στοιχεία περιοδικού: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 7909578 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-0003 (Electronic) Linking ISSN: 01418130 NLM ISO Abbreviation: Int J Biol Macromol Subsets: MEDLINE

Ιατρικοί όροι (MeSH): Lipase*/genetics , Lipase*/chemistry , Lipase*/metabolism , Polyesters*/metabolism , Polyesters*/chemistry , Polyurethanes*/metabolism , Polyurethanes*/chemistry , Cold Temperature* , Protein Engineering* , Gene Library*, Biodegradation, Environmental ; Amino Acid Sequence ; Models, Molecular

Targeted next-generation sequencing techniques: From primer design to sophisticated library construction.

Συγγραφείς: Koryukov M; Institute of Chemical Biology and Fundamental Medicine, Novosibirsk 630090, Russia; Novosibirsk State University, Novosibirsk 630090, Russia. Electronic address: mkoryukov@gmail.com., Mikheeva R; Institute of Chemical Biology and Fundamental Medicine, Novosibirsk 630090, Russia; Novosibirsk State University, Novosibirsk 630090, Russia., Kechin A; Institute of Chemical Biology and Fundamental Medicine, Novosibirsk 630090, Russia; Novosibirsk State University, Novosibirsk 630090, Russia.

Πηγή: Methods (San Diego, Calif.) [Methods] 2026 Sep; Vol. 253, pp. 31-48. Date of Electronic Publication: 2026 May 08.

Τύπος έκδοσης: Journal Article; Review

Στοιχεία περιοδικού: Publisher: Academic Press Country of Publication: United States NLM ID: 9426302 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1095-9130 (Electronic) Linking ISSN: 10462023 NLM ISO Abbreviation: Methods Subsets: MEDLINE

Ιατρικοί όροι (MeSH): High-Throughput Nucleotide Sequencing*/methods , DNA Primers*/genetics , DNA Primers*/chemistry , Gene Library*, Polymerase Chain Reaction/methods ; Sequence Analysis, DNA/methods ; Humans

Genetically Encoded Lysine-Selective Photocyclization Enables Phage Display Selection of Cyclic Peptide Binders.

Συγγραφείς: Yang XQ; State Key Laboratory of Natural Product Chemistry, Lanzhou Magnetic Resonance Center, College of Chemistry and Chemical Engineering, Lanzhou University, Lanzhou, P. R. China., Ming W; State Key Laboratory of Natural Product Chemistry, Lanzhou Magnetic Resonance Center, College of Chemistry and Chemical Engineering, Lanzhou University, Lanzhou, P. R. China.; State Key Laboratory of Drug Research, Chinese Academy of Sciences, Shanghai Institute of Materia Medica, Shanghai, P. R. China., Zhang ZH; State Key Laboratory of Natural Product Chemistry, Lanzhou Magnetic Resonance Center, College of Chemistry and Chemical Engineering, Lanzhou University, Lanzhou, P. R. China., Liu X; State Key Laboratory of Natural Product Chemistry, Lanzhou Magnetic Resonance Center, College of Chemistry and Chemical Engineering, Lanzhou University, Lanzhou, P. R. China., Bai LW; School of Pharmaceutical Sciences, South-Central Minzu University, Wuhan, P. R. China., Li ZH; School of Pharmaceutical Sciences, South-Central Minzu University, Wuhan, P. R. China., Huang R; School of Pharmaceutical Sciences, South-Central Minzu University, Wuhan, P. R. China., Chen XH; State Key Laboratory of Drug Research, Chinese Academy of Sciences, Shanghai Institute of Materia Medica, Shanghai, P. R. China.; School of Pharmaceutical Science and Technology, Hangzhou Institute For Advanced Study, University of Chinese Academy of Sciences, Hangzhou, P. R. China., Lei X; State Key Laboratory of Natural Product Chemistry, Lanzhou Magnetic Resonance Center, College of Chemistry and Chemical Engineering, Lanzhou University, Lanzhou, P. R. China.

Πηγή: Angewandte Chemie (International ed. in English) [Angew Chem Int Ed Engl] 2026 Aug 24; Vol. 65 (35), pp. e3703404. Date of Electronic Publication: 2026 Jul 09.

Τύπος έκδοσης: Journal Article; Research Support, Non-U.S. Gov't

Στοιχεία περιοδικού: Publisher: Wiley-VCH Country of Publication: Germany NLM ID: 0370543 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1521-3773 (Electronic) Linking ISSN: 14337851 NLM ISO Abbreviation: Angew Chem Int Ed Engl Subsets: MEDLINE

Ιατρικοί όροι (MeSH): Peptides, Cyclic*/chemistry , Peptides, Cyclic*/genetics , Peptides, Cyclic*/metabolism , Lysine*/chemistry , Lysine*/genetics , Peptide Library*, Cyclization ; Photochemical Processes