Long-Term Favorable Cardiac Remodeling in Obstructive Hypertrophic Cardiomyopathy Patients Treated With Mavacamten for Up to 128 Weeks: Insights From the VALOR-HCM Trial.

Authors: Desai MY; Hypertrophic Cardiomyopathy Center, Heart, Vascular and Thoracic Institute, Cleveland Clinic, Cleveland, Ohio, USA; Department of Cardiovascular Medicine, Heart, Vascular and Thoracic Institute, Cleveland Clinic, Cleveland, Ohio, USA; Cleveland Clinic Coordinating Center for Clinical Research, Heart, Vascular and Thoracic Institute, Cleveland Clinic, Cleveland, Ohio, USA. Electronic address: desaim2@ccf.org., Okushi Y; Hypertrophic Cardiomyopathy Center, Heart, Vascular and Thoracic Institute, Cleveland Clinic, Cleveland, Ohio, USA; Department of Cardiovascular Medicine, Heart, Vascular and Thoracic Institute, Cleveland Clinic, Cleveland, Ohio, USA., Wolski K; Department of Cardiovascular Medicine, Heart, Vascular and Thoracic Institute, Cleveland Clinic, Cleveland, Ohio, USA; Cleveland Clinic Coordinating Center for Clinical Research, Heart, Vascular and Thoracic Institute, Cleveland Clinic, Cleveland, Ohio, USA., Geske JB; Department of Cardiovascular Diseases, Mayo Clinic, Rochester, Minnesota, USA., Owens AT; Division of Cardiology, University of Pennsylvania, Philadelphia, Pennsylvania, USA., Wang Q; Department of Cardiovascular Medicine, Heart, Vascular and Thoracic Institute, Cleveland Clinic, Cleveland, Ohio, USA; Cleveland Clinic Coordinating Center for Clinical Research, Heart, Vascular and Thoracic Institute, Cleveland Clinic, Cleveland, Ohio, USA., Saberi S; Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan, USA., Wang A; Department of Cardiology, Duke University, Durham, North Carolina, USA., Cremer P; Department of Cardiology, Northwestern University, Chicago, Illinois, USA., Lakdawala NK; Division of Cardiology, Brigham and Women's Hospital, Boston, Massachusetts, USA., Sherrid MV; Department of Cardiology, New York University, New York, New York, USA., Tower-Rader A; Division of Cardiology, Massachusetts General Hospital, Boston, Massachusetts, USA., Fermin DR; Department of Cardiology, Corewell Health, Grand Rapids, Michigan, USA., Zenker MA; Department of Cardiology, St Thomas, Nashville, Tennessee, USA., Naidu SS; Department of Cardiology, Westchester Medical Center, Valhalla, New York, USA., Lampl K; Clinical Development, Bristol Myers Squibb, Princeton, New Jersey, USA., Nissen SE; Department of Cardiovascular Medicine, Heart, Vascular and Thoracic Institute, Cleveland Clinic, Cleveland, Ohio, USA; Cleveland Clinic Coordinating Center for Clinical Research, Heart, Vascular and Thoracic Institute, Cleveland Clinic, Cleveland, Ohio, USA., Popovic Z; Hypertrophic Cardiomyopathy Center, Heart, Vascular and Thoracic Institute, Cleveland Clinic, Cleveland, Ohio, USA; Department of Cardiovascular Medicine, Heart, Vascular and Thoracic Institute, Cleveland Clinic, Cleveland, Ohio, USA; Cleveland Clinic Coordinating Center for Clinical Research, Heart, Vascular and Thoracic Institute, Cleveland Clinic, Cleveland, Ohio, USA.

Corporate Authors: VALOR-HCM investigators

Source: JACC. Cardiovascular imaging [JACC Cardiovasc Imaging] 2025 Dec; Vol. 18 (12), pp. 1300-1311. Date of Electronic Publication: 2025 Sep 16.

Publication Type: Journal Article; Randomized Controlled Trial; Multicenter Study

Journal Info: Publisher: Elsevier Country of Publication: United States NLM ID: 101467978 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1876-7591 (Electronic) Linking ISSN: 18767591 NLM ISO Abbreviation: JACC Cardiovasc Imaging Subsets: MEDLINE

MeSH Terms: Ventricular Remodeling*/drug effects , Cardiomyopathy, Hypertrophic*/physiopathology , Cardiomyopathy, Hypertrophic*/diagnostic imaging , Cardiomyopathy, Hypertrophic*/drug therapy , Ventricular Function, Left*/drug effects , Uracil*/adverse effects , Uracil*/analogs & derivatives , Uracil*/therapeutic use , Cardiovascular Agents*/adverse effects , Cardiovascular Agents*/therapeutic use , Ventricular Outflow Obstruction*/physiopathology , Ventricular Outflow Obstruction*/diagnostic imaging , Ventricular Outflow Obstruction*/drug therapy, Humans ; Male ; Female ; Middle Aged ; Treatment Outcome ; Time Factors ; Aged ; Recovery of Function ; Atrial Function, Left/drug effects ; Prosthesis Design ; Benzylamines

Beyond volumes and ejection fraction: practical insights into cine-CMR interpretation and applications.

Authors: Vaz A; Instituto do Coração do Hospital de Clínicas da Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil. andrevaz7@gmail.com., Serra VC; Instituto do Coração do Hospital de Clínicas da Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil., de Santana Ramos DO; Instituto do Câncer do Estado de São Paulo, São Paulo, 05403-900, SP, Brazil.

Source: The international journal of cardiovascular imaging [Int J Cardiovasc Imaging] 2025 Dec; Vol. 41 (12), pp. 2299-2322. Date of Electronic Publication: 2025 Oct 03.

Publication Type: Journal Article; Review

Journal Info: Publisher: Springer Country of Publication: United States NLM ID: 100969716 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1875-8312 (Electronic) Linking ISSN: 15695794 NLM ISO Abbreviation: Int J Cardiovasc Imaging Subsets: MEDLINE

MeSH Terms: Magnetic Resonance Imaging, Cine* , Stroke Volume* , Ventricular Function, Left* , Heart Diseases*/diagnostic imaging , Heart Diseases*/physiopathology, Humans ; Predictive Value of Tests ; Reproducibility of Results ; Prognosis ; Atrial Function, Left ; Image Interpretation, Computer-Assisted

Effect of left bundle branch area pacing on cardiac remodeling and function: propensity score matching with right ventricular pacing.

Authors: Zhang S; Department of Cardiology, The Affiliated People's Hospital of Jiangsu University, 8 # Dianli Road, Zhenjiang, 212002, China., Li Z; The First Clinical Medical School of Nanjing Medical University, 140 # Hanzhong Road, Nanjing, 210029, China., Guo J; Department of Cardiology, The Affiliated People's Hospital of Jiangsu University, 8 # Dianli Road, Zhenjiang, 212002, China., Wang S; The First Clinical Medical School of Nanjing Medical University, 140 # Hanzhong Road, Nanjing, 210029, China., Jiang Z; Department of Cardiology, The First Affiliated Hospital of Nanjing Medical University, 300 # Guangzhou Road, Nanjing, 210029, China., Yang W; Department of Cardiology, The First Affiliated Hospital of Nanjing Medical University, 300 # Guangzhou Road, Nanjing, 210029, China., Cheng Y; The First Clinical Medical School of Nanjing Medical University, 140 # Hanzhong Road, Nanjing, 210029, China., Zhou X; Department of Cardiology, The First Affiliated Hospital of Nanjing Medical University, 300 # Guangzhou Road, Nanjing, 210029, China., Shan Q; Department of Cardiology, The First Affiliated Hospital of Nanjing Medical University, 300 # Guangzhou Road, Nanjing, 210029, China. qjshan@njmu.edu.cn.

Source: BMC cardiovascular disorders [BMC Cardiovasc Disord] 2025 Nov 28; Vol. 25 (1), pp. 851. Date of Electronic Publication: 2025 Nov 28.

Publication Type: Journal Article; Comparative Study

Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 100968539 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-2261 (Electronic) Linking ISSN: 14712261 NLM ISO Abbreviation: BMC Cardiovasc Disord Subsets: MEDLINE

MeSH Terms: Ventricular Remodeling* , Ventricular Function, Left* , Cardiac Pacing, Artificial*/adverse effects , Ventricular Function, Right* , Atrioventricular Block*/physiopathology , Atrioventricular Block*/therapy , Atrioventricular Block*/diagnosis , Atrioventricular Block*/diagnostic imaging , Bundle of His*/physiopathology, Humans ; Male ; Female ; Aged ; Propensity Score ; Treatment Outcome ; Middle Aged ; Time Factors ; Stroke Volume ; Retrospective Studies ; Recovery of Function ; Risk Assessment

Comparative effects of biventricular and right ventricular pacing on clinical outcomes in atrioventricular block: a systematic review and meta-analysis.

Authors: Khalid A; Department of Medicine, Dow University Of Health Sciences, Karachi, Pakistan., Rasool A; Department of Medicine, Dow University Of Health Sciences, Karachi, Pakistan., Daniyal SM; Department of Medicine, Dow University Of Health Sciences, Karachi, Pakistan., Ibrahim M; Department of Medicine, Ziauddin University, Karachi, Pakistan., Siddiqui FA; Department of Medicine, Dow University Of Health Sciences, Karachi, Pakistan., Saad M; Department of Medicine, Dow University Of Health Sciences, Karachi, Pakistan., Siddiqui MH; Department of Medicine, Dow University Of Health Sciences, Karachi, Pakistan., Balach R; Department of Medicine, Ziauddin University, Karachi, Pakistan., Ahmed HB; Department of Medicine, Dow University Of Health Sciences, Karachi, Pakistan., Gul I; Department of Medicine, Dow University Of Health Sciences, Karachi, Pakistan., Adil Y; Department of Medicine, Dow University Of Health Sciences, Karachi, Pakistan., Tabish S; Department of Medicine, Dow University Of Health Sciences, Karachi, Pakistan., Ashraf DA; Department of Medicine, TruGift Health LLC, Wilmington, DE, USA., Sajid A; Department of Medicine, Muzaffar Khan Mother and Children Hospital, Islamabad, Pakistan., Jabakhil R; Department of Medicine, Ningarhar Regional Hospital, Jalalabad, Afghanistan. romaljabarkhil@outlook.com.

Source: BMC cardiovascular disorders [BMC Cardiovasc Disord] 2025 Nov 25; Vol. 25 (1), pp. 835. Date of Electronic Publication: 2025 Nov 25.

Publication Type: Journal Article; Systematic Review; Meta-Analysis

Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 100968539 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-2261 (Electronic) Linking ISSN: 14712261 NLM ISO Abbreviation: BMC Cardiovasc Disord Subsets: MEDLINE

MeSH Terms: Atrioventricular Block*/therapy , Atrioventricular Block*/physiopathology , Atrioventricular Block*/mortality , Atrioventricular Block*/diagnosis , Ventricular Function, Left* , Cardiac Resynchronization Therapy*/adverse effects , Cardiac Resynchronization Therapy*/mortality , Ventricular Function, Right* , Heart Failure*/physiopathology , Heart Failure*/mortality , Heart Failure*/therapy , Heart Failure*/diagnosis, Humans ; Treatment Outcome ; Risk Factors ; Female ; Recovery of Function ; Male ; Time Factors ; Aged ; Middle Aged ; Exercise Tolerance ; Stroke Volume ; Randomized Controlled Trials as Topic ; Hospitalization ; Risk Assessment

Effects of exercise on cardiac structure and function in patients with type 2 diabetes: a narrative review of prospective imaging studies.

Authors: Gojevic T; Rehabilitation Research Institute (REVAL), Hasselt University, Hasselt, Belgium. tin.gojevic@uhasselt.be.; Faculty of Rehabilitation Sciences, Hasselt University, Hasselt, Belgium. tin.gojevic@uhasselt.be.; Faculty of Rehabilitation Sciences, Hasselt University, Wetenschapspark 7, Hasselt, Diepenbeek, 3590, Belgium. tin.gojevic@uhasselt.be., Machado FVC; Rehabilitation Research Institute (REVAL), Hasselt University, Hasselt, Belgium.; Faculty of Rehabilitation Sciences, Hasselt University, Hasselt, Belgium., Bekhuis Y; Department of Cardiology and Jessa & Science, Jessa Hospital, Hasselt, Belgium.; Department of Cardiology, University Hospital of Leuven, Leuven, Belgium.; Department of Cardiovascular Diseases, UZ Leuven, Leuven, Belgium.; Faculty of Medicine and Life Sciences/LCRC, UHasselt, Diepenbeek, Belgium., Claessen G; Department of Cardiology and Jessa & Science, Jessa Hospital, Hasselt, Belgium.; Department of Cardiology, University Hospital of Leuven, Leuven, Belgium.; Faculty of Medicine and Life Sciences/LCRC, UHasselt, Diepenbeek, Belgium., Cornelissen V; Faculty of Movement and Rehabilitation Sciences, Department of Rehabilitation Sciences, KU Leuven, Leuven, Belgium., De Craemer M; Faculty of Medicine and Health Sciences, Department of Rehabilitation Sciences, Ghent University, Ghent, Belgium., Dendale P; Department of Cardiology and Jessa & Science, Jessa Hospital, Hasselt, Belgium.; Faculty of Medicine and Life Sciences/LCRC, UHasselt, Diepenbeek, Belgium., Falter M; Department of Cardiology and Jessa & Science, Jessa Hospital, Hasselt, Belgium.; Faculty of Medicine and Life Sciences/LCRC, UHasselt, Diepenbeek, Belgium., Ferreira SM; Department of Cardiology and Jessa & Science, Jessa Hospital, Hasselt, Belgium.; Faculty of Medicine and Life Sciences/LCRC, UHasselt, Diepenbeek, Belgium., Herbots L; Department of Cardiology and Jessa & Science, Jessa Hospital, Hasselt, Belgium.; Faculty of Medicine and Life Sciences/LCRC, UHasselt, Diepenbeek, Belgium., Hoedemakers S; Department of Cardiology and Jessa & Science, Jessa Hospital, Hasselt, Belgium.; Faculty of Medicine and Life Sciences/LCRC, UHasselt, Diepenbeek, Belgium., Michielsen M; Faculty of Movement and Rehabilitation Sciences, Department of Rehabilitation Sciences, KU Leuven, Leuven, Belgium., Milani M; Rehabilitation Research Institute (REVAL), Hasselt University, Hasselt, Belgium.; Department of Cardiology and Jessa & Science, Jessa Hospital, Hasselt, Belgium.; Graduate Programme in Health Sciences and Technologies, University of Brasilia (UnB), Brasilia, DF, Brazil., Verwerft J; Department of Cardiology and Jessa & Science, Jessa Hospital, Hasselt, Belgium.; Faculty of Medicine and Life Sciences/LCRC, UHasselt, Diepenbeek, Belgium., Hansen D; Rehabilitation Research Institute (REVAL), Hasselt University, Hasselt, Belgium.; Faculty of Rehabilitation Sciences, Hasselt University, Hasselt, Belgium.

Source: The international journal of cardiovascular imaging [Int J Cardiovasc Imaging] 2025 Oct; Vol. 41 (10), pp. 1851-1864. Date of Electronic Publication: 2025 Jul 19.

Publication Type: Journal Article; Review

Journal Info: Publisher: Springer Country of Publication: United States NLM ID: 100969716 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1875-8312 (Electronic) Linking ISSN: 15695794 NLM ISO Abbreviation: Int J Cardiovasc Imaging Subsets: MEDLINE

MeSH Terms: Diabetes Mellitus, Type 2*/diagnosis , Diabetes Mellitus, Type 2*/complications , Diabetes Mellitus, Type 2*/therapy , Ventricular Function, Right* , Ventricular Function, Left* , Exercise Therapy*/adverse effects , Diabetic Cardiomyopathies*/diagnostic imaging , Diabetic Cardiomyopathies*/physiopathology , Diabetic Cardiomyopathies*/etiology , Diabetic Cardiomyopathies*/therapy , Heart Failure*/physiopathology , Heart Failure*/diagnostic imaging , Heart Failure*/etiology , Heart Failure*/therapy , Ventricular Remodeling*, Humans ; Treatment Outcome ; Recovery of Function ; Predictive Value of Tests ; Female ; Male ; Middle Aged ; Exercise Tolerance

Pretransplant natural antibody levels identify a subset of deceased donor kidney transplant recipients that benefit from infliximab induction.

Authors: Petr V; Department of Nephrology, Institute for Clinical and Experimental Medicine, Prague, Czech Republic; Department of Medicine, University of Colorado School of Medicine, Anschutz Medical Campus, Aurora, Colorado, USA. Electronic address: vojtech.petr@cuanschutz.edu., Tichanek F; Department of Data Science, Institute for Clinical and Experimental Medicine, Prague, Czech Republic., Liu SL; Feinberg Cardiovascular and Renal Research Institute, Northwestern University, Chicago, Illinois, USA., Poppelaars F; Department of Medicine, University of Colorado School of Medicine, Anschutz Medical Campus, Aurora, Colorado, USA., Renner B; Department of Medicine, University of Colorado School of Medicine, Anschutz Medical Campus, Aurora, Colorado, USA., Laskowski J; Department of Medicine, University of Colorado School of Medicine, Anschutz Medical Campus, Aurora, Colorado, USA., Purohit S; Department of Medicine, University of Colorado School of Medicine, Anschutz Medical Campus, Aurora, Colorado, USA., Zhao M; Feinberg Cardiovascular and Renal Research Institute, Northwestern University, Chicago, Illinois, USA., Jalal D; Department of Medicine, Carver College of Medicine, University of Iowa, Iowa City, Iowa, USA; CADRE-Center for Access and Delivery Research and Evaluation, Iowa City VA HCS, Iowa City, Iowa, USA., Heeger PS; Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, California, USA; Department of Surgery, Cedars-Sinai Medical Center, Los Angeles, California, USA; Department of Biomedical Sciences, Cedars-Sinai Medical Center, Los Angeles, California, USA., Thurman JM; Department of Medicine, University of Colorado School of Medicine, Anschutz Medical Campus, Aurora, Colorado, USA.

Source: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons [Am J Transplant] 2025 Oct; Vol. 25 (10), pp. 2173-2181. Date of Electronic Publication: 2025 Jun 06.

Publication Type: Journal Article; Randomized Controlled Trial

Journal Info: Publisher: Elsevier Country of Publication: United States NLM ID: 100968638 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1600-6143 (Electronic) Linking ISSN: 16006135 NLM ISO Abbreviation: Am J Transplant Subsets: MEDLINE

MeSH Terms: Kidney Transplantation*/adverse effects , Infliximab*/therapeutic use , Tissue Donors* , Graft Rejection*/etiology , Graft Rejection*/drug therapy , Graft Rejection*/blood , Graft Rejection*/prevention & control , Kidney Failure, Chronic*/surgery , Delayed Graft Function*/etiology , Delayed Graft Function*/drug therapy , Delayed Graft Function*/prevention & control , Antibodies, Anticardiolipin*/blood , Antibodies, Anticardiolipin*/immunology, Humans ; Male ; Female ; Middle Aged ; Glomerular Filtration Rate ; Graft Survival/drug effects ; Prognosis ; Follow-Up Studies ; Kidney Function Tests ; Adult ; Risk Factors ; Biomarkers/blood ; Immunoglobulin G/blood ; Immunoglobulin M/blood ; Transplant Recipients

Reduced Functional Status among Kidney Transplant Recipients over Time and Associated Risks Post-Transplant.

Authors: Dixon SL; Department of Medicine, Dalhousie University, Halifax, Nova Scotia, Canada., Tennankore KK; Department of Medicine, Dalhousie University, Halifax, Nova Scotia, Canada.; Division of Nephrology, Department of Medicine, Dalhousie University, Halifax, Nova Scotia, Canada., Worthen GL; Department of Medicine, Dalhousie University, Halifax, Nova Scotia, Canada.; Division of Nephrology, Department of Medicine, Dalhousie University, Halifax, Nova Scotia, Canada., Vinson AJ; Department of Medicine, Dalhousie University, Halifax, Nova Scotia, Canada.; Division of Nephrology, Department of Medicine, Dalhousie University, Halifax, Nova Scotia, Canada.

Source: Clinical transplantation [Clin Transplant] 2025 Oct; Vol. 39 (10), pp. e70353.

Publication Type: Journal Article

Journal Info: Publisher: Munksgaard Country of Publication: Denmark NLM ID: 8710240 Publication Model: Print Cited Medium: Internet ISSN: 1399-0012 (Electronic) Linking ISSN: 09020063 NLM ISO Abbreviation: Clin Transplant Subsets: MEDLINE

MeSH Terms: Kidney Transplantation*/adverse effects , Delayed Graft Function*/etiology , Delayed Graft Function*/epidemiology , Graft Rejection*/etiology , Graft Rejection*/pathology , Graft Rejection*/epidemiology , Functional Status* , Kidney Failure, Chronic*/surgery , Transplant Recipients*/statistics & numerical data , Postoperative Complications*/etiology, Humans ; Male ; Female ; Middle Aged ; Follow-Up Studies ; Risk Factors ; Prognosis ; Adult ; Graft Survival ; Retrospective Studies ; Glomerular Filtration Rate ; Kidney Function Tests ; United States/epidemiology

Transient decline and early recovery of noninvasive myocardial work after kidney transplantation: a prospective study.

Authors: Huang Y; Department of Ultrasound, The Second Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang, Jiangxi, China., Jin L; Department of Ultrasound, The Second Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang, Jiangxi, China., Qiu X; Department of Ultrasound, The Second Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang, Jiangxi, China., Yang C; Department of Ultrasound, The Second Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang, Jiangxi, China., Ping L; Department of Ultrasound, The Second Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang, Jiangxi, China., Jiang Z; Department of Transplantation, The Second Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang, Jiangxi, China., Zou H; Department of Transplantation, The Second Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang, Jiangxi, China., Zhang Z; School of Public Health, Jiangxi Medical College, Nanchang University, Jiangxi Provincial Key Laboratory of Disease Prevention and Public Health, Nanchang University, Nanchang, Jiangxi, China., Wang J; Department of Ultrasound, The Second Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang, Jiangxi, China.

Source: Renal failure [Ren Fail] 2025 Dec; Vol. 47 (1), pp. 2543930. Date of Electronic Publication: 2025 Aug 11.

Publication Type: Journal Article

Journal Info: Publisher: Informa Healthcare Country of Publication: England NLM ID: 8701128 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1525-6049 (Electronic) Linking ISSN: 0886022X NLM ISO Abbreviation: Ren Fail Subsets: MEDLINE

MeSH Terms: Kidney Transplantation* , Renal Insufficiency, Chronic*/surgery , Renal Insufficiency, Chronic*/complications , Renal Insufficiency, Chronic*/physiopathology , Ventricular Function, Left*/physiology, Humans ; Male ; Female ; Middle Aged ; Prospective Studies ; Adult ; Echocardiography ; Glomerular Filtration Rate ; Blood Urea Nitrogen ; Blood Pressure ; Recovery of Function ; Creatinine/blood

PCSK9 inhibitor improved cardiac function after acute myocardial infarction in rats.

Authors: An H; Department of General Medicine, Lanzhou University Second Hospital, Lanzhou, Gansu, China. Electronic address: zh_gw@petrochina.com.cn., Zhu J; Department of Rehabilitation, Lanzhou Third Peoples Hospital, Lanzhou, Gansu, China., Li Q; Department of Pediatric Rheumatology and Immunology, Lanzhou University Second Hospital, Lanzhou, Gansu, China.

Source: Microvascular research [Microvasc Res] 2025 Nov; Vol. 162, pp. 104847. Date of Electronic Publication: 2025 Jul 24.

Publication Type: Journal Article

Journal Info: Publisher: Academic Press Country of Publication: United States NLM ID: 0165035 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1095-9319 (Electronic) Linking ISSN: 00262862 NLM ISO Abbreviation: Microvasc Res Subsets: MEDLINE

MeSH Terms: Myocardial Infarction*/physiopathology , Myocardial Infarction*/drug therapy , Myocardial Infarction*/enzymology , Myocardial Infarction*/pathology , PCSK9 Inhibitors* , Ventricular Function, Left*/drug effects , Myocardium*/pathology , Myocardium*/enzymology , Antibodies, Monoclonal, Humanized*/pharmacology , Serine Proteinase Inhibitors*/pharmacology , Myocytes, Cardiac*/pathology , Myocytes, Cardiac*/drug effects , Myocytes, Cardiac*/enzymology, Animals ; Disease Models, Animal ; Male ; Proprotein Convertase 9/metabolism ; Proprotein Convertase 9/genetics ; Ventricular Remodeling/drug effects ; Signal Transduction ; Recovery of Function ; Apoptosis/drug effects ; Rats, Sprague-Dawley ; Biomarkers/blood ; Cytokines/blood ; Inflammation Mediators/blood ; Fibrosis

Recovery of Fatigue, Cardiorespiratory Fitness, and Neuromuscular Function in COVID-19 ICU Patients: A 6-Month Follow-Up Study.

Authors: Kennouche D; Université Jean Monnet Saint-Etienne, Lyon 1, Université Savoie Mont-Blanc, Laboratoire Interuniversitaire de Biologie de la Motricité, Saint-Etienne, FRANCE., Foschia C; Service de Physiologie Clinique et de l'Exercice, Hôpital Universitaire de Saint-Etienne, Saint-Etienne, FRANCE., Brownstein CG; School of Biomedical, Nutritional, and Sport Sciences, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, UNITED KINGDOM., Gondin J; Institut NeuroMyoGène (INMG), Physiopathologie et Génétique du Neurone et du Muscle (PGNM), CNRS 5261-INSERM U1315-UCBL1, Faculté de Médecine et de Pharmacie, Lyon, FRANCE., Lapole T; Université Jean Monnet Saint-Etienne, Lyon 1, Université Savoie Mont-Blanc, Laboratoire Interuniversitaire de Biologie de la Motricité, Saint-Etienne, FRANCE., Rimaud D; Université Jean Monnet Saint-Etienne, Lyon 1, Université Savoie Mont-Blanc, Laboratoire Interuniversitaire de Biologie de la Motricité, Saint-Etienne, FRANCE., Royer N; Université Jean Monnet Saint-Etienne, Lyon 1, Université Savoie Mont-Blanc, Laboratoire Interuniversitaire de Biologie de la Motricité, Saint-Etienne, FRANCE., Thiery G; Service de Médecine Intensive Réanimation, Centre Hospitalier Universitaire de Saint-Etienne, Saint-Etienne & Research on Healthcare Performance RESHAPE, INSERM U1290, Université Claude Bernard Lyon 1, FRANCE., Gauthier V; Réanimation, Clinique Mutualiste, Saint Etienne, France., Giraux P; CHU Saint-Etienne, Service Médecine Physique et Réadaptation, Saint-Etienne, FRANCE., Oujamaa L; Service de Rééducation Post-Réanimation SRPR 42, Groupement de Coopération Sanitaire Fondation Partage et Vie & Centre Hospitalier Universitaire de Saint Etienne, Saint-Etienne, FRANCE., Sorg M; Service de Physiologie Clinique et de l'Exercice, Hôpital Universitaire de Saint-Etienne, Saint-Etienne, FRANCE., Vergès S; Univ. Grenoble Alpes, INSERM U1300, CHU Grenoble Alpes, HP2 laboratory, Grenoble, FRANCE., Doutreleau S; Univ. Grenoble Alpes, INSERM U1300, CHU Grenoble Alpes, HP2 laboratory, Grenoble, FRANCE., Marillier M; Univ. Grenoble Alpes, INSERM U1300, CHU Grenoble Alpes, HP2 laboratory, Grenoble, FRANCE., Prudent M; Service d'Explorations Fonctionnelles Respiratoires-Médecine duSsport et de L'activité Physique, Hospices Civils de Lyon, Lyon, FRANCE., Bitker L; Service de Médecine Intensive-Réanimation, Hôpital de la Croix Rousse, Hospices Civils de Lyon, Lyon, France & Univ Lyon, INSA-Lyon, Université Claude Bernard Lyon 1, UJM-Saint Etienne, CNRS, Inserm, CREATIS UMR 5220, U1206, Villeurbanne, FRANCE., Féasson L; Université Jean Monnet Saint-Etienne, Lyon 1, Université Savoie Mont-Blanc, Laboratoire Interuniversitaire de Biologie de la Motricité, Saint-Etienne, FRANCE., Gergelé L; Ramsay Générale de Santé, Hôpital privé de la Loire, Saint-Etienne, FRANCE., Stauffer E; Service d'Explorations Fonctionnelles Respiratoires-Médecine duSsport et de L'activité Physique, Hospices Civils de Lyon, Lyon, FRANCE., Guichon C; Département Anesthésie Réanimation, Hôpital de la Croix Rousse, Hospices Civils de Lyon, Lyon, FRANCE., Morel J, Millet GY

Source: Medicine and science in sports and exercise [Med Sci Sports Exerc] 2025 Nov 01; Vol. 57 (11), pp. 2409-2418. Date of Electronic Publication: 2025 Jun 13.

Publication Type: Journal Article

Journal Info: Publisher: Lippincott Williams & Wilkins Country of Publication: United States NLM ID: 8005433 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1530-0315 (Electronic) Linking ISSN: 01959131 NLM ISO Abbreviation: Med Sci Sports Exerc Subsets: MEDLINE

MeSH Terms: COVID-19*/physiopathology , COVID-19*/complications , COVID-19*/therapy , Fatigue*/physiopathology , Fatigue*/etiology , Cardiorespiratory Fitness*/physiology , Recovery of Function*, Humans ; Male ; Female ; Middle Aged ; Intensive Care Units ; Follow-Up Studies ; Aged ; Exercise Test ; SARS-CoV-2 ; Respiratory Function Tests ; Respiration, Artificial ; Oxygen Consumption ; Adult

Withdrawing guideline-directed medical therapy after left ventricular ejection fraction recovery following atrial fibrillation ablation: a multicentre cohort study.

Authors: Al-Aidarous S; St Bartholomew's Hospital, London, UK.; Queen Mary University of London, London, UK., Rajappan S; UCLMS, University College London Medical School, London, UK.; Cardiac Department, Oxford University Hospitals NHS Trust, Oxford, UK., Ahluwalia N; St Bartholomew's Hospital, London, UK., Uy CP; St Bartholomew's Hospital, London, UK.; Barking Havering and Redbridge Hospitals NHS Trust, Romford, UK., Abdelgawad H; Royal Bournemouth Hospital, University Hospitals Dorset NHS Foundation Trust, Poole, UK., Vidal Horrach C; Queen Mary University of London, London, UK., Kouadria S; St Bartholomew's Hospital, London, UK., Hua Z; St Bartholomew's Hospital, London, UK.; Queen Mary University of London, London, UK., Sandhar G; St Bartholomew's Hospital, London, UK.; UCLMS, University College London Medical School, London, UK., Cooke T; St Bartholomew's Hospital, London, UK., Rasheed S; Lister Hospital, Stevenage, UK., Geran S; Barking Havering and Redbridge Hospitals NHS Trust, Romford, UK., Chiew KLX; Cardiology, Whittington Hospital, London, UK.; Imperial College London National Heart and Lung Institute, London, UK., Lehri M; Homerton University Hospital NHS Trust, London, UK., Palaiologos D; Lister Hospital, Stevenage, UK., Khalil A; Cardiology, North Middlesex University Hospital, London, UK., Kennedy B; Royal Berkshire Hospital, Reading, UK., Balasubramaniam R; Royal Bournemouth Hospital, University Hospitals Dorset NHS Foundation Trust, Poole, UK., Hussain S; St Bartholomew's Hospital, London, UK.; Cardiology, North Middlesex University Hospital, London, UK., Stanton L; Dorset County Hospital NHS Foundation Trust, Dorchester, UK., Ahsan S; St Bartholomew's Hospital, London, UK.; Cardiology, North Middlesex University Hospital, London, UK., Primus C; St Bartholomew's Hospital, London, UK.; University College London Hospitals NHS Foundation Trust, London, UK., Chow AWC; St Bartholomew's Hospital, London, UK.; Royal Berkshire Hospital, Reading, UK., Thomas M; St Bartholomew's Hospital, London, UK., Muthumala A; St Bartholomew's Hospital, London, UK.; Cardiology, North Middlesex University Hospital, London, UK., Sohaib SMA; St Bartholomew's Hospital, London, UK.; Barking Havering and Redbridge Hospitals NHS Trust, Romford, UK., Ang R; St Bartholomew's Hospital, London, UK.; Homerton University Hospital NHS Trust, London, UK., Papageorgiou N; St Bartholomew's Hospital, London, UK.; Lister Hospital, Stevenage, UK., Butcher C; Dorset County Hospital NHS Foundation Trust, Dorchester, UK.; University Hospitals Dorset NHS Foundation Trust, Poole, UK., Rajappan K; Cardiac Department, Oxford University Hospitals NHS Trust, Oxford, UK., Roney C; Queen Mary University of London, London, UK., Hunter RJ; St Bartholomew's Hospital, London, UK., Honarbakhsh S; St Bartholomew's Hospital, London, UK shohreh.honarbakhsh@nhs.net.; Queen Mary University of London, London, UK.

Source: Open heart [Open Heart] 2025 Oct 13; Vol. 12 (2). Date of Electronic Publication: 2025 Oct 13.

Publication Type: Journal Article; Multicenter Study

Journal Info: Publisher: BMJ Publishing Group Country of Publication: England NLM ID: 101631219 Publication Model: Electronic Cited Medium: Print ISSN: 2053-3624 (Print) Linking ISSN: 20533624 NLM ISO Abbreviation: Open Heart Subsets: MEDLINE

MeSH Terms: Atrial Fibrillation*/physiopathology , Atrial Fibrillation*/surgery , Atrial Fibrillation*/complications , Atrial Fibrillation*/therapy , Atrial Fibrillation*/diagnosis , Stroke Volume*/physiology , Catheter Ablation*/adverse effects , Ventricular Function, Left*/physiology , Ventricular Function, Left*/drug effects , Practice Guidelines as Topic* , Anti-Arrhythmia Agents*/administration & dosage , Anti-Arrhythmia Agents*/adverse effects , Ventricular Dysfunction, Left*/physiopathology , Ventricular Dysfunction, Left*/etiology, Humans ; Male ; Female ; Middle Aged ; Recovery of Function ; Aged ; Treatment Outcome ; Follow-Up Studies ; United Kingdom ; Time Factors

Impact of Donor and Recipient Sex on Long-Term Outcomes Following Living Donor Kidney Transplantation: A Retrospective Dual-Center Study.

Authors: Fang Y; Erasmus MC Transplant Institute, Department of Surgery, Division of HPB and Transplant Surgery, Erasmus Medical Center, Rotterdam, Netherlands., Westenberg LB; Division of Transplantation Surgery, Department of Surgery, University Medical Center Groningen, University of Groningen, Groningen, Netherlands., Hamm JJM; Erasmus MC Transplant Institute, Department of Surgery, Division of HPB and Transplant Surgery, Erasmus Medical Center, Rotterdam, Netherlands., van de Wetering J; Erasmus MC Transplant Institute, University Medical Center Rotterdam, Department of Internal Medicine, Division of Nephrology and Transplantation, Rotterdam, Netherlands., Bakker SJL; Division of Nephrology, Department of Internal Medicine, University Medical Center Groningen, University of Groningen, Groningen, Netherlands., de Bruin RWF; Erasmus MC Transplant Institute, Department of Surgery, Division of HPB and Transplant Surgery, Erasmus Medical Center, Rotterdam, Netherlands., Pol RA; Division of Transplantation Surgery, Department of Surgery, University Medical Center Groningen, University of Groningen, Groningen, Netherlands., Minnee RC; Erasmus MC Transplant Institute, Department of Surgery, Division of HPB and Transplant Surgery, Erasmus Medical Center, Rotterdam, Netherlands.

Source: Clinical transplantation [Clin Transplant] 2025 Oct; Vol. 39 (10), pp. e70335.

Publication Type: Journal Article; Multicenter Study; Observational Study

Journal Info: Publisher: Munksgaard Country of Publication: Denmark NLM ID: 8710240 Publication Model: Print Cited Medium: Internet ISSN: 1399-0012 (Electronic) Linking ISSN: 09020063 NLM ISO Abbreviation: Clin Transplant Subsets: MEDLINE

MeSH Terms: Delayed Graft Function*/etiology , Delayed Graft Function*/mortality , Graft Rejection*/etiology , Graft Rejection*/mortality , Graft Rejection*/pathology , Kidney Failure, Chronic*/surgery , Kidney Failure, Chronic*/mortality , Kidney Transplantation*/mortality , Kidney Transplantation*/adverse effects , Living Donors*/supply & distribution , Postoperative Complications*/mortality , Transplant Recipients*/statistics & numerical data, Adult ; Female ; Humans ; Male ; Middle Aged ; Follow-Up Studies ; Glomerular Filtration Rate ; Graft Survival ; Kidney Function Tests ; Prognosis ; Retrospective Studies ; Risk Factors ; Sex Factors ; Survival Rate

Two-Dimensional Speckle Tracking Echocardiography and Real-Time Three-Dimensional Echocardiography in Marathon Runners: A Study of Left Atrium.

Authors: Yang P; Department of Echocardiography of The Third Affiliated Hospital of Soochow University, Changzhou First People's Hospital, Changzhou City, Jiangsu Province, China., Ge Z; Department of Echocardiography of The Third Affiliated Hospital of Soochow University, Changzhou First People's Hospital, Changzhou City, Jiangsu Province, China., Wang L; Department of Echocardiography of The Third Affiliated Hospital of Soochow University, Changzhou First People's Hospital, Changzhou City, Jiangsu Province, China., Ke H; Department of Cardiovascular Division of The Third Affiliated Hospital of Soochow University, Changzhou First People's Hospital, Changzhou City, Jiangsu Province, China., Xu M; Department of Echocardiography of The Third Affiliated Hospital of Soochow University, Changzhou First People's Hospital, Changzhou City, Jiangsu Province, China.

Source: Clinical cardiology [Clin Cardiol] 2025 Dec; Vol. 48 (12), pp. e70230.

Publication Type: Journal Article

Journal Info: Publisher: John Wiley & Sons, Inc Country of Publication: United States NLM ID: 7903272 Publication Model: Print Cited Medium: Internet ISSN: 1932-8737 (Electronic) Linking ISSN: 01609289 NLM ISO Abbreviation: Clin Cardiol Subsets: MEDLINE

MeSH Terms: Echocardiography, Three-Dimensional*/methods , Heart Atria*/diagnostic imaging , Heart Atria*/physiopathology , Atrial Function, Left*/physiology , Marathon Running*/physiology , Echocardiography*/methods , Hypertrophy, Left Ventricular*/physiopathology , Hypertrophy, Left Ventricular*/diagnostic imaging , Running*, Humans ; Male ; Female ; Adult ; Middle Aged ; Stroke Volume ; Ventricular Function, Left ; Predictive Value of Tests ; Case-Control Studies

Long term impact of percutaneous transvenous mitral commissurotomy (PTMC) on left atrial remodeling in rheumatic mitral stenosis.

Authors: Beig JR; Deptartment of Cardiology, Super Speciality Hospital, Government Medical College, Srinagar, 190010, Jammu and Kashmir, India., Kumar D; Deptartment of Cardiology, SKIMS, Soura, Srinagar, Jammu and Kashmir, India., Rashid W; Deptartment of Cardiology, Super Speciality Hospital, Government Medical College, Srinagar, 190010, Jammu and Kashmir, India. wasim.rashid@hotmail.com., Haq I; Deptartment of SPM, Government Medical College, Srinagar, Jammu and Kashmir, India., Achakzai KK; Deptartment of Cardiology, Super Speciality Hospital, Government Medical College, Srinagar, 190010, Jammu and Kashmir, India., Mir KM; Deptartment of Cardiology, Super Speciality Hospital, Government Medical College, Srinagar, 190010, Jammu and Kashmir, India., Naiku BA; Deptartment of Cardiology, Super Speciality Hospital, Government Medical College, Srinagar, 190010, Jammu and Kashmir, India., Tramboo NA; Deptartment of Cardiology, SKIMS, Soura, Srinagar, Jammu and Kashmir, India.

Source: The international journal of cardiovascular imaging [Int J Cardiovasc Imaging] 2025 Dec; Vol. 41 (12), pp. 2407-2414. Date of Electronic Publication: 2025 Nov 03.

Publication Type: Journal Article; Observational Study

Journal Info: Publisher: Springer Country of Publication: United States NLM ID: 100969716 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1875-8312 (Electronic) Linking ISSN: 15695794 NLM ISO Abbreviation: Int J Cardiovasc Imaging Subsets: MEDLINE

MeSH Terms: Mitral Valve Stenosis*/physiopathology , Mitral Valve Stenosis*/diagnostic imaging , Mitral Valve Stenosis*/therapy , Mitral Valve Stenosis*/surgery , Atrial Function, Left* , Atrial Remodeling* , Rheumatic Heart Disease*/physiopathology , Rheumatic Heart Disease*/diagnostic imaging , Rheumatic Heart Disease*/therapy , Mitral Valve*/physiopathology , Mitral Valve*/diagnostic imaging , Mitral Valve*/surgery , Cardiac Catheterization*/adverse effects, Humans ; Female ; Prospective Studies ; Treatment Outcome ; Male ; Time Factors ; Adult ; Recovery of Function ; Severity of Illness Index ; Stroke Volume ; Young Adult ; Middle Aged

Reduced left atrial compliance exacerbates primary graft dysfunction after lung transplantation.

Authors: Schäfer M; Division of Cardiothoracic Surgery, University of Utah, Salt Lake City, Utah. Electronic address: michal.schafer@hsc.utah.edu., Selzman CH; Division of Cardiothoracic Surgery, University of Utah, Salt Lake City, Utah., DiChiacchio L; Division of Cardiothoracic Surgery, Cedars-Sinai, Los Angeles, Calif., Heiler JC; Division of Cardiothoracic Surgery, University of Utah, Salt Lake City, Utah., Ramakrishna S; Division of Cardiology, University of Utah, Salt Lake City, Utah., Tumarkin E; Division of Cardiology, University of Utah, Salt Lake City, Utah., Hill B; Department of Anesthesiology, University of Utah, Salt Lake City, Utah., Kagawa H; Division of Cardiothoracic Surgery, University of Utah, Salt Lake City, Utah., Contreras N; Division of Cardiothoracic Surgery, University of Utah, Salt Lake City, Utah., Raman S; Division of Pulmonary Medicine, University of Utah, Salt Lake City, Utah., Frye L; Division of Pulmonary Medicine, University of Utah, Salt Lake City, Utah., Cahill B; Division of Pulmonary Medicine, University of Utah, Salt Lake City, Utah., Morrell M; Division of Pulmonary Medicine, University of Utah, Salt Lake City, Utah., Goodwin ML; Division of Cardiothoracic Surgery, University of Utah, Salt Lake City, Utah.

Source: The Journal of thoracic and cardiovascular surgery [J Thorac Cardiovasc Surg] 2025 Dec; Vol. 170 (6), pp. 1840-1849. Date of Electronic Publication: 2025 May 04.

Publication Type: Journal Article

Journal Info: Publisher: Mosby Country of Publication: United States NLM ID: 0376343 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-685X (Electronic) Linking ISSN: 00225223 NLM ISO Abbreviation: J Thorac Cardiovasc Surg Subsets: MEDLINE

MeSH Terms: Lung Transplantation*/adverse effects , Primary Graft Dysfunction*/physiopathology , Primary Graft Dysfunction*/etiology , Primary Graft Dysfunction*/diagnostic imaging , Atrial Function, Left* , Heart Atria*/physiopathology , Heart Atria*/diagnostic imaging, Humans ; Female ; Male ; Middle Aged ; Risk Factors ; Adult ; Retrospective Studies ; Risk Assessment ; Ventricular Function, Left ; Compliance

The mineralocorticoid receptor antagonist finerenone enhances cardiovascular recovery upon food intake normalization in obese mice.

Authors: Manon MF; Univ Rouen-Normandie UNIROUEN, Normandie Université, Inserm UMRS-1096 EnVI, 76000, Rouen, France., Marie PD; Univ Rouen-Normandie UNIROUEN, Normandie Université, Inserm UMRS-1096 EnVI, 76000, Rouen, France., Benjamin B; Sorbonne Université, Université Paris Cité, Inserm U-1138, Centre de Recherche des Cordeliers, 75006, InsermParis, France., Coralie F; Univ Rouen-Normandie UNIROUEN, Normandie Université, Inserm UMRS-1096 EnVI, 76000, Rouen, France., Linghui K; Univeristé Paris Cité, Inserm, Paris Cardiovascular Research Center (PARCC), 75015, Paris, France., Amhrae ND; Univ Rouen-Normandie UNIROUEN, Normandie Université, Inserm UMRS-1096 EnVI, 76000, Rouen, France., Lionel N; Univ Rouen-Normandie UNIROUEN, Normandie Université, Inserm UMRS-1096 EnVI, 76000, Rouen, France., Saïda M; Univ Rouen-Normandie UNIROUEN, Normandie Université, Inserm UMRS-1096 EnVI, 76000, Rouen, France., Sylvanie R; Univ Rouen-Normandie UNIROUEN, Normandie Université, Inserm UMRS-1096 EnVI, 76000, Rouen, France., Anaïs D; Univ Rouen-Normandie UNIROUEN, Normandie Université, Inserm UMRS-1096 EnVI, 76000, Rouen, France., Vincent R; Univ Rouen-Normandie UNIROUEN, Normandie Université, Inserm UMRS-1096 EnVI, 76000, Rouen, France., Bruno F; Inserm UMRS-938, Centre de Recherche Saint-Antoine-(CRSA), Saint-Antoine Hospital, Department of Endocrinology, CRMR PRISIS, Sorbonne Université,Institut Hospitalo-Universitaire de Cardio-Métabolisme et Nutrition (ICAN), 75012, Paris, France., Frédéric J; Sorbonne Université, Université Paris Cité, Inserm U-1138, Centre de Recherche des Cordeliers, 75006, InsermParis, France., Sheerazed B; Univeristé Paris Cité, Inserm, Paris Cardiovascular Research Center (PARCC), 75015, Paris, France., Paul M; Univ Rouen-Normandie UNIROUEN, Normandie Université, Inserm UMRS-1096 EnVI, 76000, Rouen, France., Antoine OP; Univ Rouen-Normandie UNIROUEN, Normandie Université, Inserm UMRS-1096 EnVI, 76000, Rouen, France. antoine.ouvrard-pascaud@univ-rouen.fr.

Source: Cardiovascular diabetology [Cardiovasc Diabetol] 2025 Nov 24; Vol. 24 (1), pp. 446. Date of Electronic Publication: 2025 Nov 24.

Publication Type: Journal Article

Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101147637 Publication Model: Electronic Cited Medium: Internet ISSN: 1475-2840 (Electronic) Linking ISSN: 14752840 NLM ISO Abbreviation: Cardiovasc Diabetol Subsets: MEDLINE

MeSH Terms: Mineralocorticoid Receptor Antagonists*/pharmacology , Obesity*/physiopathology , Obesity*/drug therapy , Obesity*/blood , Obesity*/complications , Ventricular Function, Left*/drug effects , Naphthyridines*/pharmacology , Eating*/drug effects , Heart Failure*/physiopathology , Heart Failure*/etiology , Heart Failure*/drug therapy, Animals ; Disease Models, Animal ; Diet, High-Fat ; Male ; Mice, Inbred C57BL ; Blood Glucose/metabolism ; Blood Glucose/drug effects ; Recovery of Function ; Time Factors ; Insulin Resistance ; Stroke Volume/drug effects ; Mice ; Weight Loss/drug effects

RRAD-reduction reveals efficacy of targeting L-type calcium channel regulation for treatment of heart failure.

Authors: Elmore G; Department of Physiology, University of Kentucky, 741 S. Limestone, Lexington, KY 40536-0298, USA., Lohano SS; Department of Physiology, University of Kentucky, 741 S. Limestone, Lexington, KY 40536-0298, USA., McVay NM; Department of Physiology, University of Kentucky, 741 S. Limestone, Lexington, KY 40536-0298, USA., Levitan BM; Department of Physiology, University of Kentucky, 741 S. Limestone, Lexington, KY 40536-0298, USA.; Gill Heart and Vascular Institute, University of Kentucky, Lexington, KY 40506, USA., Sebastian A; Department of Physiology, University of Kentucky, 741 S. Limestone, Lexington, KY 40536-0298, USA., Barker KW; Department of Physiology, University of Kentucky, 741 S. Limestone, Lexington, KY 40536-0298, USA., Dupont A; Department of Physiology, University of Kentucky, 741 S. Limestone, Lexington, KY 40536-0298, USA., Leung SW; Gill Heart and Vascular Institute, University of Kentucky, Lexington, KY 40506, USA., Abouleisa RRE; Division of Cardiothoracic Surgery, Department of Surgery, Baylor College of Medicine, Houston, TX 77030, USA., Mathew PR; Division of Cardiothoracic Surgery, Department of Surgery, Baylor College of Medicine, Houston, TX 77030, USA., Wellette-Hunsucker A; Department of Physiology, University of Kentucky, 741 S. Limestone, Lexington, KY 40536-0298, USA., Minton AT; Department of Physiology, University of Kentucky, 741 S. Limestone, Lexington, KY 40536-0298, USA., Campbell KS; Department of Physiology, University of Kentucky, 741 S. Limestone, Lexington, KY 40536-0298, USA.; Department of Medicine/Cardiology, University of Kentucky HealthCare, Lexington, KY 40506, USA., Harrar SW; Department of Statistics, University of Kentucky, Lexington, KY 40506, USA., Mehri M; Department of Mechanical and Aerospace Engineering, University of Kentucky, Lexington, KY 40506, USA., Wenk JF; Department of Mechanical and Aerospace Engineering, University of Kentucky, Lexington, KY 40506, USA., Mohamed TMA; Division of Cardiothoracic Surgery, Department of Surgery, Baylor College of Medicine, Houston, TX 77030, USA., Andres DA; Department of Biochemistry, University of Kentucky, Lexington, KY 40506, USA., Satin J; Department of Physiology, University of Kentucky, 741 S. Limestone, Lexington, KY 40536-0298, USA.

Source: Cardiovascular research [Cardiovasc Res] 2025 Nov 22; Vol. 121 (14), pp. 2204-2221.

Publication Type: Journal Article

Journal Info: Publisher: Oxford Journals Country of Publication: England NLM ID: 0077427 Publication Model: Print Cited Medium: Internet ISSN: 1755-3245 (Electronic) Linking ISSN: 00086363 NLM ISO Abbreviation: Cardiovasc Res Subsets: MEDLINE

MeSH Terms: Calcium Channels, L-Type*/metabolism , Calcium Channels, L-Type*/genetics , Calcium Channels, L-Type*/drug effects , Heart Failure*/metabolism , Heart Failure*/physiopathology , Heart Failure*/genetics , Heart Failure*/therapy , Myocytes, Cardiac*/metabolism , Myocytes, Cardiac*/pathology , Myocytes, Cardiac*/drug effects , Cardiomyopathy, Dilated*/metabolism , Cardiomyopathy, Dilated*/physiopathology , Cardiomyopathy, Dilated*/genetics , Cardiomyopathy, Dilated*/therapy , Ventricular Function, Left* , Calcium Signaling*/drug effects , Muscle Proteins*/genetics , Muscle Proteins*/metabolism , Muscle Proteins*/deficiency , LIM Domain Proteins*/genetics , LIM Domain Proteins*/metabolism , LIM Domain Proteins*/deficiency, Animals ; Humans ; Disease Models, Animal ; Mice, Knockout ; Male ; Stroke Volume ; Mice, Inbred C57BL ; Ventricular Remodeling ; Female ; Recovery of Function ; ras Proteins

Persistent Shift in Principal Strain Angles and Postsurgical Decline in Left Ventricular Ejection Fraction in Patients With Primary Mitral Regurgitation.

Authors: Dell'Italia LJ; Birmingham Veterans Affairs Health Care System Birmingham AL USA.; Division of Cardiovascular Disease University of Alabama at Birmingham Birmingham AL USA., Kane MS; Birmingham Veterans Affairs Health Care System Birmingham AL USA.; Division of Cardiovascular Disease University of Alabama at Birmingham Birmingham AL USA., Zheng J; Department of Mathematics and Statistics Auburn University Auburn AL USA., Huang SW; Department of Mathematics and Statistics Auburn University Auburn AL USA., Pat B; Birmingham Veterans Affairs Health Care System Birmingham AL USA.; Division of Cardiovascular Disease University of Alabama at Birmingham Birmingham AL USA., Denney TS Jr; Samuel Ginn College of Engineering Auburn University Auburn AL USA.

Source: Journal of the American Heart Association [J Am Heart Assoc] 2025 Nov 18; Vol. 14 (22), pp. e043558. Date of Electronic Publication: 2025 Nov 17.

Publication Type: Journal Article

Journal Info: Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 101580524 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2047-9980 (Electronic) Linking ISSN: 20479980 NLM ISO Abbreviation: J Am Heart Assoc Subsets: MEDLINE

MeSH Terms: Mitral Valve Insufficiency*/surgery , Mitral Valve Insufficiency*/physiopathology , Mitral Valve Insufficiency*/diagnostic imaging , Mitral Valve Insufficiency*/diagnosis , Stroke Volume* , Ventricular Function, Left* , Mitral Valve*/surgery , Mitral Valve*/physiopathology , Mitral Valve*/diagnostic imaging , Ventricular Dysfunction, Left*/physiopathology , Ventricular Dysfunction, Left*/etiology, Humans ; Male ; Female ; Middle Aged ; Aged ; Treatment Outcome ; Recovery of Function ; Severity of Illness Index ; Magnetic Resonance Imaging, Cine ; Ventricular Remodeling ; Time Factors ; Case-Control Studies ; Heart Ventricles/physiopathology ; Heart Ventricles/diagnostic imaging

Long-term effectiveness of ACE inhibitors or angiotensin receptor blockers in myocardial infarction with preserved left ventricular ejection fraction.

Authors: Humphreys ABC; Unit of Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, 17177 Stockholm, Sweden., Lindahl B; Department of Medical Sciences, Uppsala University, 751 85 Uppsala, Sweden., Berglund A; Unit of Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, 17177 Stockholm, Sweden., Voelskow V; Institute of Public Health, Charité-Universitätsmedizin Berlin, 10117 Berlin, Germany., Fang S; MRC Integrative Epidemiology Unit, Population Health Sciences, Bristol Medical School, University of Bristol, Bristol BS8 2BN, UK., Fröbert O; Department of Cardiology, Faculty of Health, Örebro University Hospital, 70362 Örebro, Sweden.; Department of Clinical Medicine, Aarhus University Hospital, 8200 Aarhus, Denmark.; Department of Clinical Pharmacology, Aarhus University Hospital, 8200 Aarhus, Denmark.; Steno Diabetes Center Aarhus, Aarhus University Hospital, 8200 Aarhus, Denmark., Hofmann R; Department of Clinical Science and Education, Division of Cardiology, Karolinska Institutet, Södersjukhuset, 11883 Stockholm, Sweden., Jernberg T; Department of Clinical Sciences, Danderyd University Hospital-Karolinska Institutet, 18288 Stockholm, Sweden., Hernán MA; Unit of Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, 17177 Stockholm, Sweden.; CAUSALab, Department of Epidemiology, Harvard T. H. Chan School of Public Health, Boston, MA 02115, USA.; Department of Biostatistics, Harvard T. H. Chan School of Public Health, Boston, MA 02115, USA., Matthews AA; Unit of Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, 17177 Stockholm, Sweden.

Source: European heart journal. Cardiovascular pharmacotherapy [Eur Heart J Cardiovasc Pharmacother] 2025 Nov 04; Vol. 11 (7), pp. 600-609.

Publication Type: Journal Article; Observational Study; Comparative Study

Journal Info: Publisher: Oxford University Press Country of Publication: England NLM ID: 101669491 Publication Model: Print Cited Medium: Internet ISSN: 2055-6845 (Electronic) NLM ISO Abbreviation: Eur Heart J Cardiovasc Pharmacother Subsets: MEDLINE

MeSH Terms: Angiotensin-Converting Enzyme Inhibitors*/therapeutic use , Angiotensin-Converting Enzyme Inhibitors*/adverse effects , Myocardial Infarction*/drug therapy , Myocardial Infarction*/physiopathology , Myocardial Infarction*/mortality , Myocardial Infarction*/diagnosis , Stroke Volume*/drug effects , Angiotensin Receptor Antagonists*/therapeutic use , Angiotensin Receptor Antagonists*/adverse effects , Ventricular Function, Left*/drug effects, Humans ; Male ; Female ; Middle Aged ; Aged ; Sweden/epidemiology ; Registries ; Treatment Outcome ; Time Factors ; Risk Factors ; Heart Failure/mortality ; Heart Failure/physiopathology ; Heart Failure/prevention & control ; Risk Assessment ; Recovery of Function

Sacubitril/valsartan and quality of life assessed using the EuroQol Five-dimension Three-level questionnaire level sum score (EQ-5D-3L-LSS) in patients with HFrEF and HFmrEF/HFpEF.

Authors: Yang M; British Heart Foundation Cardiovascular Research Centre, University of Glasgow, 126 University Place, Glasgow G12 8TA, UK.; Department of Cardiology, Zhongda Hospital, School of Medicine, Southeast University, Nanjing 210009, China., Henderson AD; British Heart Foundation Cardiovascular Research Centre, University of Glasgow, 126 University Place, Glasgow G12 8TA, UK., Anand IS; Department of Cardiovascular Medicine, University of Minnesota, Minneapolis, MN 55455, USA., Desai AS; Cardiovascular Division, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA., Lam CSP; National Heart Centre Singapore & Duke-National University of Singapore  169609, Singapore., Maggioni AP; ANMCO Research Center, Heart Care Foundation, Florence 50121, Italy., Martinez FA; Universidad Nacional de Córdoba, Córdoba X5000, Argentina., Rouleau JL; Institut de Cardiologie de Montréal, Université de Montréal, Montréal H1T 1C8, Canada., Swedberg K; Department of Emergency and Cardiovascular Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg 40530, Sweden., Vaduganathan M; Cardiovascular Division, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA., van Veldhuisen DJ; Department of Cardiology, Thorax Center, University Medical Center, Postbus 30.001, 9700 RB Groningen, the Netherlands., Zannad F; Inserm Clinical Investigation Centre, CHU, Université de Lorraine, Nancy 54500, France., Zile MR; RHJ Department of Veterans Affairs Medical Center, Medical University of South Carolina, Charleston, SC 29401, USA., Packer M; Baylor Heart and Vascular Institute, Baylor University Medical Center, Dallas, TX 75226, USA., Rizkala A; Novartis Pharmaceuticals Corporation, East Hanover, NJ 07936, USA., Lewis EF; Division of Cardiovascular Medicine, Stanford University School of Medicine, Stanford University, Palo Alto, CA 94305, USA., Jhund PS; British Heart Foundation Cardiovascular Research Centre, University of Glasgow, 126 University Place, Glasgow G12 8TA, UK., Solomon SD; Cardiovascular Division, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA., McMurray JJV; British Heart Foundation Cardiovascular Research Centre, University of Glasgow, 126 University Place, Glasgow G12 8TA, UK.

Source: European heart journal. Cardiovascular pharmacotherapy [Eur Heart J Cardiovasc Pharmacother] 2025 Nov 04; Vol. 11 (7), pp. 574-589.

Publication Type: Journal Article; Randomized Controlled Trial

Journal Info: Publisher: Oxford University Press Country of Publication: England NLM ID: 101669491 Publication Model: Print Cited Medium: Internet ISSN: 2055-6845 (Electronic) NLM ISO Abbreviation: Eur Heart J Cardiovasc Pharmacother Subsets: MEDLINE

MeSH Terms: Aminobutyrates*/therapeutic use , Aminobutyrates*/adverse effects , Valsartan*/therapeutic use , Valsartan*/adverse effects , Heart Failure*/drug therapy , Heart Failure*/physiopathology , Heart Failure*/mortality , Heart Failure*/diagnosis , Heart Failure*/psychology , Quality of Life* , Stroke Volume*/drug effects , Ventricular Function, Left*/drug effects , Tetrazoles*/therapeutic use , Tetrazoles*/adverse effects , Angiotensin II Type 1 Receptor Blockers*/adverse effects , Angiotensin II Type 1 Receptor Blockers*/therapeutic use , Protease Inhibitors*/therapeutic use , Protease Inhibitors*/adverse effects , Angiotensin Receptor Antagonists*/therapeutic use , Angiotensin Receptor Antagonists*/adverse effects, Humans ; Biphenyl Compounds ; Drug Combinations ; Male ; Female ; Aged ; Treatment Outcome ; Middle Aged ; Time Factors ; Surveys and Questionnaires ; Recovery of Function ; Neprilysin/antagonists & inhibitors ; Risk Factors