Caffeine Therapy in Preterm Neonates: Mechanisms, Clinical Applications, and Long-term Outcomes – A Narrative Review.

Συγγραφείς: Mathusudhanan, Suresh Palani^1,2 (AUTHOR) drsureshpalani5102@gmail.com

Πηγή: Journal of Clinical Neonatology. Oct-Dec2025, Vol. 14 Issue 4, p160-165. 6p.

Θεματικοί όροι: *CAFFEINE, *APNEA of prematurity, *NEURAL development, *CLINICAL medicine, *NEWBORN infants, *DRUG dosage, *ADENOSINES

Polygraphic Results in High-Risk Infants Aged Under 3 Months.

Συγγραφείς: Zenteno, Daniel^1,2 (AUTHOR), Torres-Puebla, Gerardo² (AUTHOR), Sánchez, Camila^1,3 (AUTHOR), Gutiérrez, Rocío^1,4 (AUTHOR), Elso, María José³ (AUTHOR), Brockmann, Pablo E.⁴ (AUTHOR) pbrockmann@gmail.com

Πηγή: Clocks & Sleep. Sep2025, Vol. 7 Issue 3, p42. 13p.

Θεματικοί όροι: *APNEA of prematurity, *PREMATURE infants, *INFANT health, *CARDIOPULMONARY system, *APNEA, *SOMNOLOGY, *CONTROL groups, *POLYSOMNOGRAPHY

Modeling Patient-Specific Apnea-Bradycardia Patterns in Preterm Newborn

Συγγραφείς: Duport, O., Le Rolle, V., Guerrero, G., Beuchee, A., Hernandez, A.

Πηγή: IEEE Transactions on Biomedical Engineering IEEE Trans. Biomed. Eng. Biomedical Engineering, IEEE Transactions on. 72(3):1067-1077 Mar, 2025

Extended Caffeine for Apnea in Moderately Preterm Infants: The MoCHA Randomized Clinical Trial.

Συγγραφείς: Carlo, Waldemar A.¹ (AUTHOR) wacarlo@uabmc.edu, Eichenwald, Eric C.² (AUTHOR), Carper, Benjamin A.³ (AUTHOR), Bell, Edward F.⁴ (AUTHOR), Keszler, Martin⁵ (AUTHOR), Patel, Ravi M.⁶ (AUTHOR), Sánchez, Pablo J.⁷ (AUTHOR), Goldberg, Ronald N.⁸ (AUTHOR), D'Angio, Carl T.⁹ (AUTHOR), Van Meurs, Krisa P.¹⁰ (AUTHOR), Hibbs, Anna Maria¹¹ (AUTHOR), Ambalavanan, Namasivayam¹ (AUTHOR), Cosby, Shirley S.¹ (NURSE), Newman, Nancy S.¹¹ (NURSE), Vohr, Betty R.⁵ (AUTHOR), Walsh, Michele C.¹² (AUTHOR), Das, Abhik¹³ (AUTHOR), Ohls, Robin K.¹⁴ (AUTHOR), Fuller, Janell¹⁵ (AUTHOR), Rysavy, Matthew A.¹⁶ (AUTHOR)

Πηγή: JAMA: Journal of the American Medical Association. 6/24/2025, Vol. 333 Issue 24, p2154-2163. 10p.

Θεματικοί όροι: *EMERGENCY room visits, *APNEA of prematurity, *PREMATURE infants, *STATISTICAL significance, *CLINICAL trials

Heart Rate Variability Does Not Predict Recurrence of Apnoea of Prematurity After Ceasing Caffeine Therapy: A Prospective Cohort Study.

Συγγραφείς: Kaempfen, Siree¹ (AUTHOR) siree.kaempfen@ukbb.ch, Hug, Mareike¹ (AUTHOR), Sanchez, Carlos² (AUTHOR), Delgado‐Eckert, Edgar^2,3 (AUTHOR), Schulzke, Sven M.¹ (AUTHOR)

Πηγή: Acta Paediatrica. Jun2025, Vol. 114 Issue 6, p1371-1378. 8p.

Θεματικοί όροι: *APNEA of prematurity, *PREMATURE infants, *BRONCHOPULMONARY dysplasia, *CAFFEINE, *COHORT analysis, *COMORBIDITY, *ENTROPY (Information theory), *HEART beat

Caffeine Therapy for Apnea of Prematurity: Single-Center Study on Dosing Practices and Perceived Effectiveness.

Συγγραφείς: Storm, Kelly K.¹ (AUTHOR), Flint, Robert B.^1,2 (AUTHOR), Onland, Wes^3,4 (AUTHOR), van Kaam, Anton H.^3,4 (AUTHOR), Reiss, Irwin K.M.¹ (AUTHOR), Hutten, G. Jeroen^3,4 (AUTHOR), Simons, Sinno H.P.¹ (AUTHOR)

Πηγή: Neonatology (16617800). 2025, Vol. 122 Issue 3, p290-301. 12p.

Θεματικοί όροι: *CAFFEINE, *APNEA of prematurity, *MEDICAL practice, *NEONATAL intensive care, *DRUG dosage, *RETROSPECTIVE studies, *DRUG therapy

Effect of caffeine citrate on diaphragmatic electrical activity in pre-term newborns.

Συγγραφείς: Zidan, Tatiana B.B.¹ (AUTHOR) tatizidan@hotmail.com, Troster, Eduardo J.¹ (AUTHOR), Beck, Jennifer² (AUTHOR), Sanches, Livia R.³ (AUTHOR), Ferreira, Carlos Eduardo S.³ (AUTHOR), Zacharias, Romy S.B.¹ (AUTHOR), Rebello, Celso M.¹ (AUTHOR)

Πηγή: PLoS ONE. 4/11/2025, Vol. 20 Issue 4, p1-10. 10p.

Θεματικοί όροι: *APNEA of prematurity, *RESPIRATORY muscles, *BIRTH weight, *GESTATIONAL age, *NEWBORN infants

Explainable Machine Learning for Central Apnea Detection in Premature Infants

Συγγραφείς: Varisco, Gabriele, Peng, Zheng, Andriessen, Peter, Van Pul, Carola, Long, Xi

Πηγή: 2024 IEEE International Symposium on Medical Measurements and Applications (MeMeA) Medical Measurements and Applications (MeMeA), 2024 IEEE International Symposium on. :1-6 Jun, 2024

Relation: 2024 IEEE International Symposium on Medical Measurements and Applications (MeMeA)

Clinical efficacy of different maintenance doses of caffeine citrate in the treatment of apnea of prematurity.

Συγγραφείς: Ping Ji¹, Yu Wan¹ wanyu1123456@126.com, Jiansong Yin¹, Mei Xue¹, Jing Wang¹, Liwen Zhang²

Πηγή: Pakistan Journal of Medical Sciences. Feb2025, Vol. 41 Issue 2, p478-483. 6p.

Θεματικοί όροι: *APNEA of prematurity, *DRUG dosage, *PREMATURE infants, *MEDICAL care costs, *STATISTICAL significance

Incidence and Risk Factors for Retinopathy of Prematurity (Rop): A Prospective Follow-up Study from Sub-himalayan Union Territory (UT) of India.

Συγγραφείς: Gupta, Riya¹ (AUTHOR), Gupta, Satish K.¹ (AUTHOR), Gupta, Rajiv K.² (AUTHOR), Gupta, Surbhi¹ (AUTHOR), Mahajan, Richa² (AUTHOR) dr.richamahajan27@gmail.com, Kumari, Rashmi² (AUTHOR), Langer, Bhavna² (AUTHOR)

Πηγή: Medical Journal of Dr. D.Y. Patil Vidyapeeth. Jan/Feb2025, Vol. 18 Issue 1, p32-36. 5p.

Θεματικοί όροι: *RETROLENTAL fibroplasia, *APNEA of prematurity, *BIRTH weight, *GESTATIONAL age, *INFANT care

Determinants of neonatal mortality at Kamenge Teaching Hospital, Burundi: a prospective cohort study.

Συγγραφείς: Ndayishimiye, Jean Claude, Iradukunda, Arnaud, Ndabashinze, Rodrigue, Manirabaruta, Martin, Ahishakiye, Alain, Mbele, Whiteson, de Dieu Nkurunziza, Jean, Habonimana, Desire

Πηγή: BMC Public Health; 11/24/2025, Vol. 25 Issue 1, p1-9, 9p

Θεματικοί όροι: NEONATAL mortality, COHORT analysis, HEALTH policy, HOSPITALS, APNEA of prematurity, APGAR score, NEONATOLOGY

Γεωγραφικοί όροι: BURUNDI, BUJUMBURA (Burundi)

Narrative review of neurodevelopmental and psychiatric complications associated with prematurity.

Συγγραφείς: Ibrahim, Halimat, Wilkins, Alyssa, Ali, Sumera Aziz, Lisonkova, Sarka, Chan, Natalie H., Ting, Joseph Y.

Πηγή: BMC Pediatrics; 11/14/2025, Vol. 25 Issue 1, p1-15, 15p

Θεματικοί όροι: NEURAL development, COGNITION disorders, NEONATOLOGY, RESEARCH methodology evaluation, APNEA of prematurity, CLINICAL medicine, HEALTH outcome assessment

Prematurity and Epigenetic Regulation of SLC6A4 : Longitudinal Insights from Birth to the First Month of Life.

Συγγραφείς: Brasil, Aline de Araújo, Milone, Leo Travassos Vieira, dos Santos, Paulo Victor Barbosa Eleutério, Saide, Stephanie Cristina Alves de Oliveira, Paravidino, Vitor Barreto, Chalfun, Georgia, Ferreira, Letícia Santiago da Silva, Ferreira, Mariana Berquó Carneiro, Ferreira, Anna Beatriz Muniz, de Farias, Geovanna Barroso, Robaina, Jaqueline Rodrigues, de Oliveira, Mariana Barros Genuíno, de Magalhães-Barbosa, Maria Clara, Prata-Barbosa, Arnaldo, da Cunha, Antonio José Ledo Alves

Πηγή: Biomedicines; Nov2025, Vol. 13 Issue 11, p2753, 23p

Θεματικοί όροι: EPIGENETICS, DNA methylation, INFANT development, LONGITUDINAL method, PREMATURE infants, SEROTONIN transporters, APNEA of prematurity, NEURAL development

Investigating the interplay between prematurity and genetic variation in the context of rare developmental disorders.

Συγγραφείς: Wootton, Olivia, Campbell, Patrick, Richardson, Sarah, Lindsay, Sarah J., Huang, Qin Qin, Delage, Erwan, Amanat, Sana, Wong, Hilary S., Firth, Helen V., Hurles, Matthew E., Simpson, Michael A., Radford, Elizabeth J., Martin, Hilary C.

Πηγή: Genome Medicine; 10/30/2025, Vol. 17 Issue 1, p1-19, 19p

Θεματικοί όροι: GENETIC variation, GENETIC mutation, DNA sequencing, PHENOTYPIC plasticity, PERVASIVE child development disorders, APNEA of prematurity, GENETIC disorder diagnosis

Time series and factors associated with prematurity in live births in curitiba, brazil: time series analysis between the years 2000 and 2021.

Συγγραφείς: Fernandes Da Silva Frigotto, Marcelle, Santos Freire de Paula, Isabela Cristina, Daniel, Isabelle Cristina, de Macedo Brondani, Arianny, Mendes, Angela Leite, Baldani, Márcia Helena, Carvalho, Deborah Ribeiro, Rocha Orsi, Juliana Schaia, Werneck, Renata Iani

Πηγή: BMC Pregnancy & Childbirth; 10/8/2025, Vol. 25 Issue 1, p1-10, 10p

Θεματικοί όροι: TIME series analysis, SOCIAL determinants of health, PREGNANCY complications, NEWBORN infants, CHILDREN'S health, APNEA of prematurity, PRENATAL care

Γεωγραφικοί όροι: CURITIBA (Brazil), BRAZIL

The Role of Perinatal Complications in Neurodevelopmental Outcomes of ART-Conceived Children: Prognostic Model for Brain Immaturity.

Συγγραφείς: Ilmuratova, Sevara, Lokshin, Vyacheslav, Nurgaliyeva, Zhanar, Kеmelbekov, Kаnatzhan, Kulniyazova, Gulshat, Abdykalykova, Bibigul, Seisebayeva, Roza, Zhubanysheva, Karlygash, Altynbayeva, Gulmira, Mukhambetova, Gulnar, Sadykova, Ainur, Marapov, Damir, Nekhorosheva, Valeriya, Manzhuova, Lyazat

Πηγή: Biomedicines; Oct2025, Vol. 13 Issue 10, p2551, 13p

Θεματικοί όροι: PREGNANCY complications, NEURAL development, FERTILIZATION in vitro, NEUROLOGICAL disorders, APNEA of prematurity, EARLY medical intervention, PROGNOSTIC models

Proteomic Analysis of Nasopharyngeal Aspirate Biomarkers for Prematurity-Related Bronchopulmonary Dysplasia.

Συγγραφείς: Garrido-Muñoz, Fernando, Fernández-Vega, Alejandro, Gregorio-Hernández, Rebeca, Padín-Fontán, Marta, Heras-Martín, Mónica de las, Teresa-Palacio, Marta, Alonso-Quintela, Paula, Trujillo-Fagundo, Alberto, Pérez-Pérez, Alba, Pumarada-Prieto, Marcelino, Montero-Gato, Jon, Aldecoa-Bilbao, Victoria, Oulego-Erroz, Ignacio, Sánchez-Fernández, Mario, Alonso-Ojembarrena, Almudena

Πηγή: CHEST; Oct2025, Vol. 168 Issue 4, p980-993, 14p

Θεματικοί όροι: BIOMARKERS, BRONCHOPULMONARY dysplasia, APNEA of prematurity, PROTEOMICS, RESPIRATORY aspiration, PREMATURE infants, DIAGNOSIS

A cost-effectiveness analysis for high versus standard (low) dose caffeine for the treatment of apnea in neonatal intensive care unit.

Συγγραφείς: Al-Hersh, Eilan¹ (AUTHOR), Abushanab, Dina² (AUTHOR), AbouNahia, Fouad³ (AUTHOR), Rainkie, Daniel⁴ (AUTHOR), Al Hail, Moza² (AUTHOR), Abdulrouf, Palli Valapila² (AUTHOR), El-Kassem, Wessam² (AUTHOR), Al-Badriyeh, Daoud⁵ (AUTHOR) daoud.a@qu.edu.qa

Πηγή: Journal of Pharmaceutical Policy & Practice. Dec2024, Vol. 17 Issue 1, p1-24. 24p.

Θεματικοί όροι: *DRUG dosage, *APNEA of prematurity, *PATENT ductus arteriosus, *NEONATAL intensive care, *TREATMENT duration

To Caffeinate or Not to Caffeinate? The Dilemma in Neonatal Apnea Management.

Συγγραφείς: Prakash, Raj¹ (AUTHOR) raj.prakash@nhs.net, Kunhiabdullah, Shafeeque² (AUTHOR), Ezzat, Medhat³ (AUTHOR)

Πηγή: Journal of Clinical Neonatology. Oct-Dec2024, Vol. 13 Issue 4, p162-167. 6p.

Θεματικοί όροι: *CENTRAL nervous system stimulants, *APNEA of prematurity, *CEREBRAL hemorrhage, *PREMATURE infants, *CEREBRAL circulation

AMPK Phosphorylates LMX1b to Regulate a Brainstem Neurogenic Network Important for Control of Breathing in Neonatal Mice.

Συγγραφείς: Marin, Traci, Wilson, Christopher, Ramirez, Miguel, Sun, Wei, Malhotra, Atul, Gongol, Brendan

Πηγή: International Journal of Molecular Sciences. 26(1)

Θεματικοί όροι: AMPK, AOP, Lmx1b, SIDS, apnea, apnea of prematurity, brainstem, respiratory center maturation, sudden infant death syndrome, ventilatory drive, Animals, Brain Stem, Mice, Phosphorylation, AMP-Activated Protein Kinases, Animals, Newborn, Respiration, Transcription Factors, Metformin, Neurogenesis, Homeodomain Proteins, Apnea, Humans

Περιγραφή αρχείου: application/pdf

Σύνδεσμος πρόσβασης: https://escholarship.org/uc/item/3j5028kq
https://escholarship.org/content/qt3j5028kq/qt3j5028kq.pdf