Associations of plasma SMOC1 and soluble IL6RA levels with the progression from mild cognitive impairment to dementia

Συγγραφείς: Xavier Morató, Raquel Puerta, Amanda Cano, Adelina Orellana, Itziar de Rojas, María Capdevila, Laura Montrreal, Maitée Rosende-Roca, Pablo García-González, Claudia Olivé, Fernando García-Gutiérrez, Josep Blázquez, Andrea Miguel, Raúl Núñez-Llaves, Vanesa Pytel, Montserrat Alegret, María Victoria Fernández, Marta Marquié, Sergi Valero, Jose Enrique Cavazos, Santos Mañes, Mercè Boada, Alfredo Cabrera-Socorro, Agustín Ruiz

Πηγή: Brain, Behavior, & Immunity - Health, Vol 42, Iss , Pp 100899- (2024)

Θεματικοί όροι: sIL6RA, SMOC1, Alzheimer's disease, Inflammation, Mild cognitive impairment, Disease progression, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571

Περιγραφή αρχείου: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2666354624001777; https://doaj.org/toc/2666-3546

Σύνδεσμος πρόσβασης: https://doaj.org/article/cec0c618b8b14d4db849327800647c8b

Clinical value of plasma pTau181 to predict Alzheimer's disease pathology in a large real-world cohort of a memory clinicResearch in context

Συγγραφείς: Amanda Cano, María Capdevila, Raquel Puerta, Javier Arranz, Laura Montrreal, Itziar de Rojas, Pablo García-González, Claudia Olivé, Fernando García-Gutiérrez, Oscar Sotolongo-Grau, Adelina Orellana, Nuria Aguilera, Maribel Ramis, Maitee Rosende-Roca, Alberto Lleó, Juan Fortea, Juan Pablo Tartari, Asunción Lafuente, Liliana Vargas, Alba Pérez-Cordón, Nathalia Muñoz, Ángela Sanabria, Montserrat Alegret, Xavier Morató, Lluís Tárraga, Victoria Fernández, Marta Marquié, Sergi Valero, Daniel Alcolea, Mercè Boada, Agustín Ruiz

Πηγή: EBioMedicine, Vol 108, Iss , Pp 105345- (2024)

Θεματικοί όροι: Plasma biomarkers, pTau181, Alzheimer's disease, Prodromal AD, Mild cognitive impairment, Real-world cohort, Medicine, Medicine (General), R5-920

Περιγραφή αρχείου: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2352396424003815; https://doaj.org/toc/2352-3964

Σύνδεσμος πρόσβασης: https://doaj.org/article/ea62dd3fe9524f3a9be6195fdbea9857

Author Correction: Systematic protein-protein interaction mapping for clinically relevant human GPCRs

Συγγραφείς: Kate Sokolina, Saranya Kittanakom, Jamie Snider, Max Kotlyar, Pascal Maurice, Jorge Gandía, Abla Benleulmi-Chaachoua, Kenjiro Tadagaki, Atsuro Oishi, Victoria Wong, Ramy H Malty, Viktor Deineko, Hiroyuki Aoki, Shahreen Amin, Zhong Yao, Xavier Morató, David Otasek, Hiroyuki Kobayashi, Javier Menendez, Daniel Auerbach, Stephane Angers, Natasa Pržulj, Michel Bouvier, Mohan Babu, Francisco Ciruela, Ralf Jockers, Igor Jurisica, Igor Stagljar

Πηγή: Molecular Systems Biology, Vol 21, Iss 2, Pp 208-209 (2025)

Θεματικοί όροι: Biology (General), QH301-705.5, Medicine (General), R5-920

Περιγραφή αρχείου: electronic resource

Relation: https://doaj.org/toc/1744-4292

Σύνδεσμος πρόσβασης: https://doaj.org/article/55626dd9b64f4aab89c7764787eccaa2

A randomized, open-label clinical trial in mild cognitive impairment with EGb 761 examining blood markers of inflammation and oxidative stress

Συγγραφείς: Xavier Morató, Marta Marquié, Juan Pablo Tartari, Asunción Lafuente, Carla Abdelnour, Montserrat Alegret, Sara Jofresa, Mar Buendía, Ana Pancho, Núria Aguilera, Marta Ibarria, Susana Diego, Rosario Cuevas, Laia Cañada, Anna Calvet, Ester Esteban-De Antonio, Alba Pérez-Cordón, Ángela Sanabria, Itziar de Rojas, Raúl Nuñez-Llaves, Amanda Cano, Adelina Orellana, Laura Montrreal, Pilar Cañabate, Maitée Rosende-Roca, Liliana Vargas, Urszula Bojaryn, Mario Ricciardi, Diana M. Ariton, Ana Espinosa, Gemma Ortega, Nathalia Muñoz, Núria Lleonart, Emilio Alarcón-Martín, Mariola Moreno, Silvia Preckler, Natalia Tantinya, Maribel Ramis, Ana Belen Nogales, Susanna Seguer, Elvira Martín, Vanesa Pytel, Sergi Valero, Miren Gurruchaga, Lluís Tárraga, Agustín Ruiz, Mercè Boada

Πηγή: Scientific Reports, Vol 13, Iss 1, Pp 1-12 (2023)

Θεματικοί όροι: Medicine, Science

Περιγραφή αρχείου: electronic resource

Relation: https://doaj.org/toc/2045-2322

Σύνδεσμος πρόσβασης: https://doaj.org/article/364131bc9f264d6d977ae7a38ff1ad31

Feasibility and usability of remote monitoring in Alzheimer's disease

Συγγραφείς: Marijn Muurling, Casper de Boer, Chris Hinds, Alankar Atreya, Aiden Doherty, Vasilis Alepopoulos, Jelena Curcic, Anna-Katharine Brem, Pauline Conde, Sajini Kuruppu, Xavier Morató, Valentina Saletti, Samantha Galluzzi, Estefania Vilarino Luis, Sandra Cardoso, Tina Stukelj, Milica Gregorič Kramberger, Dora Roik, Ivan Koychev, Ann-Cecilie Hopøy, Emilia Schwertner, Mara Gkioka, Dag Aarsland, Pieter Jelle Visser

Πηγή: Digital Health, Vol 10 (2024)

Θεματικοί όροι: Computer applications to medicine. Medical informatics, R858-859.7

Περιγραφή αρχείου: electronic resource

Relation: https://doaj.org/toc/2055-2076

Σύνδεσμος πρόσβασης: https://doaj.org/article/8f9d109ddcd94a5bb7f99894759bc08c

Automatized FACEmemory® scoring is related to Alzheimer’s disease phenotype and biomarkers in early-onset mild cognitive impairment: the BIOFACE cohort

Συγγραφείς: Montserrat Alegret, Oscar Sotolongo-Grau, Ester Esteban de Antonio, Alba Pérez-Cordón, Adelina Orellana, Ana Espinosa, Silvia Gil, Daniel Jiménez, Gemma Ortega, Angela Sanabria, Natalia Roberto, Isabel Hernández, Maitee Rosende-Roca, Juan Pablo Tartari, Emilio Alarcon-Martin, Itziar de Rojas, Laura Montrreal, Xavier Morató, Amanda Cano, Dorene M. Rentz, Lluís Tárraga, Agustín Ruiz, Sergi Valero, Marta Marquié, Mercè Boada

Πηγή: Alzheimer’s Research & Therapy, Vol 14, Iss 1, Pp 1-11 (2022)

Θεματικοί όροι: Endophenotype, Early detection, Alzheimer’s disease, New technologies, Episodic memory, Computerized assessment, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571, Neurology. Diseases of the nervous system, RC346-429

Περιγραφή αρχείου: electronic resource

Relation: https://doaj.org/toc/1758-9193

Σύνδεσμος πρόσβασης: https://doaj.org/article/90d73df7dc834a4e98282fe33746ebc0

Ecto-GPR37: a potential biomarker for Parkinson’s disease

Συγγραφείς: Xavier Morató, Paula Garcia-Esparcia, Josep Argerich, Franc Llorens, Inga Zerr, Wojciech Paslawski, Eva Borràs, Eduard Sabidó, Ulla E. Petäjä-Repo, Víctor Fernández-Dueñas, Isidro Ferrer, Per Svenningsson, Francisco Ciruela

Πηγή: Translational Neurodegeneration, Vol 10, Iss 1, Pp 1-14 (2021)

Θεματικοί όροι: GPR37, Pael-R, Parkinson’s disease, Cerebrospinal fluid, Biomarker, Alzheimer’s disease, Neurology. Diseases of the nervous system, RC346-429

Περιγραφή αρχείου: electronic resource

Relation: https://doaj.org/toc/2047-9158

Σύνδεσμος πρόσβασης: https://doaj.org/article/a6c99e3a8f2b442ca223489faa5b0b8f

A minimally invasive dried blood spot biomarker test for the detection of Alzheimer’s disease pathology

Συγγραφείς: Hanna Huber, Laia Montoliu-Gaya, Wagner S. Brum, Jakub Vávra, Yara Yakoub, Haley Weninger, Luisa Sophie Braun-Wohlfahrt, Joel Simrén, Mercé Boada, Agustín Ruiz, Amanda Cano, Adelina Orellana, Sergi Valero, Laia Cañada, Natalia Tantinya, Ana Belen Nogales, Pilar Sanz-Cartagena, Anna Dittrich, Ingmar Skoog, Millie Sander-Long, Clive Ballard, Megan Richards, Mary O’Leary, Frederikke Kragh Clemmensen, Hannah H. D. Wandall, Daniele Altomare, Valentina Cantoni, Erik Stomrud, Sebastian Palmqvist, Alberto Lleo, Daniel Alcolea, Maria Carmona Iragui, Aida Sanjuan Hernandez, Bessy Benejam, Laura Videla Toro, Alpana Singh, Marisa N. Denkinger, Anja Hviid Simonsen, Silke Kern, Anne Corbett, Juan Fortea, Lee Honigberg, Barbara Borroni, Oskar Hansson, Xavier Morató, Kaj Blennow, Henrik Zetterberg, Nicholas J. Ashton

Πηγή: Nat Med
Nature medicine 32(2), 599-608 (2026). doi:10.1038/s41591-025-04080-0

Θεματικοί όροι: Male, Aged, 80 and over, Dried Blood Spot Testing: methods, tau Proteins: blood, Alzheimer Disease: diagnosis, tau Proteins, MAPT protein, human, Middle Aged, Alzheimer Disease: blood, Article, Neurofilament Proteins: blood, Alzheimer Disease: pathology, Biomarkers: blood, Neurofilament Proteins, Glial Fibrillary Acidic Protein, Humans, Biomarkers: cerebrospinal fluid, Female, Glial Fibrillary Acidic Protein: blood, Phosphorylation, neurofilament protein L, Biomarkers, Aged

Σύνδεσμος πρόσβασης: https://pubmed.ncbi.nlm.nih.gov/41491101
https://pubmed.ncbi.nlm.nih.gov/41491101/
https://doi.org/10.1038/s41591-025-04080-0
https://pmc.ncbi.nlm.nih.gov/articles/PMC12920126/
https://pub.dzne.de/record/285353

Inhibition of Tryptophan Hydroxylases and Monoamine Oxidase-A by the Proton Pump Inhibitor, Omeprazole—In Vitro and In Vivo Investigations

Συγγραφείς: Nibal Betari, Kristoffer Sahlholm, Xavier Morató, Héctor Godoy-Marín, Olga Jáuregui, Knut Teigen, Francisco Ciruela, Jan Haavik

Πηγή: Frontiers in Pharmacology, Vol 11 (2020)

Θεματικοί όροι: serotonin, drug repurposing, high-throughput screening assay, molecular docking analysis, enzyme assay, allosteric site, Therapeutics. Pharmacology, RM1-950

Περιγραφή αρχείου: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fphar.2020.593416/full; https://doaj.org/toc/1663-9812

Σύνδεσμος πρόσβασης: https://doaj.org/article/441f33ddf4ad4ea2ae91b5c0606f75b8

Epilepsy in Neurodegenerative Diseases: Related Drugs and Molecular Pathways

Συγγραφείς: Amanda Cano, Elena Fonseca, Miren Ettcheto, Elena Sánchez-López, Itziar de Rojas, Silvia Alonso-Lana, Xavier Morató, Eliana B. Souto, Manuel Toledo, Mercè Boada, Marta Marquié, Agustín Ruíz

Πηγή: Pharmaceuticals, Vol 14, Iss 10, p 1057 (2021)

Θεματικοί όροι: epilepsy, neurodegenerative diseases, Alzheimer’s disease, Parkinson’s disease, Huntington’s disease, multiple sclerosis, Medicine, Pharmacy and materia medica, RS1-441

Περιγραφή αρχείου: electronic resource

Relation: https://www.mdpi.com/1424-8247/14/10/1057; https://doaj.org/toc/1424-8247

Σύνδεσμος πρόσβασης: https://doaj.org/article/02977393a23d46d0b367ce5d3171a8f9

Angiotensin II type 1/adenosine A 2A receptor oligomers: a novel target for tardive dyskinesia

Συγγραφείς: Paulo A. de Oliveira, James A. R. Dalton, Marc López-Cano, Adrià Ricarte, Xavier Morató, Filipe C. Matheus, Andréia S. Cunha, Christa E. Müller, Reinaldo N. Takahashi, Víctor Fernández-Dueñas, Jesús Giraldo, Rui D. Prediger, Francisco Ciruela

Πηγή: Scientific Reports, Vol 7, Iss 1, Pp 1-12 (2017)

Θεματικοί όροι: Medicine, Science

Περιγραφή αρχείου: electronic resource

Relation: https://doaj.org/toc/2045-2322

Σύνδεσμος πρόσβασης: https://doaj.org/article/627f7a95432f4193ae2fb95d8887e02b

SK2 Channels Associate With mGlu1α Receptors and CaV2.1 Channels in Purkinje Cells

Συγγραφείς: Rafael Luján, Carolina Aguado, Francisco Ciruela, Xavier Morató Arus, Alejandro Martín-Belmonte, Rocío Alfaro-Ruiz, Jesús Martínez-Gómez, Luis de la Ossa, Masahiko Watanabe, John P. Adelman, Ryuichi Shigemoto, Yugo Fukazawa

Πηγή: Frontiers in Cellular Neuroscience, Vol 12 (2018)

Θεματικοί όροι: cerebellum, potassium channel, mGlu receptor, electron microscopy, immunohistochemistry, calcium channel, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571

Περιγραφή αρχείου: electronic resource

Relation: https://www.frontiersin.org/article/10.3389/fncel.2018.00311/full; https://doaj.org/toc/1662-5102

Σύνδεσμος πρόσβασης: https://doaj.org/article/cc73b8e617aa4231bce64b3eafc5e63f

Comparative proteomic analysis of cerebrospinal fluid and brain tissue using Orbitrap Astral and timsTOF Pro 2 platforms with data-independent acquisition

Συγγραφείς: Miyo K. Chatanaka, Maria Pascual Lorén, Cassandra J. Wong, Antoninus Soosaipillai, Mercè Boada, Laura Molina-Porcel, Xavier Morató, Ioannis Prassas, Eleftherios P. Diamandis

Πηγή: Diagnosis.

Validation of human kallikrein 6 in the cerebrospinal fluid of patients with progressive and non-progressive alzheimer’s disease: correlation with other biomarkers

Συγγραφείς: Miyo K. Chatanaka, Antoninus Soosaipillai, Amanda Cano, Adelina Orellana, Mercè Boada, Ioannis Prassas, Xavier Morató, Eleftherios P. Diamandis

Πηγή: Clinical Proteomics. 23

Triglyceride Form of Docosahexaenoic Acid Mediates Neuroprotection in Experimental Parkinsonism

Συγγραφείς: Maricel Gómez-Soler, Begoña Cordobilla, Xavier Morató, Víctor Fernández-Dueñas, Joan C. Domingo, Francisco Ciruela

Πηγή: Frontiers in Neuroscience, Vol 12 (2018)

Θεματικοί όροι: docosahexaenoic acid, Parkinson’s disease, beam walking test, motor coordination, balance, omega-3 polyunsaturated fatty acids, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571

Περιγραφή αρχείου: electronic resource

Relation: https://www.frontiersin.org/article/10.3389/fnins.2018.00604/full; https://doaj.org/toc/1662-453X

Σύνδεσμος πρόσβασης: https://doaj.org/article/17c0649f6f8740c7801889bdb9717075

Neurological and inflammatory biomarkers in CSF along the Alzheimer's Disease spectrum

Συγγραφείς: Demos, Catherine, Brown, Jermaine, Ngo, Brian, de Rojas, Itziar, Casales, Federico, Fernández, Victoria, Blazquez, Josep, Chatanaka, Miyo K, Sanz, Pilar, Valero, Sergi, Boada, Mercè, Diamandis, Eleftherios P, Stengelin, Martin, Mathew, Anu, Sigal, George, Arús, Xavier Morató, Wohlstadter, Jacob N

Πηγή: Alzheimers Dement

Θεματικοί όροι: Biomarkers

Σύνδεσμος πρόσβασης: https://pmc.ncbi.nlm.nih.gov/articles/PMC12733682/
https://doi.org/10.1002/alz70856_097201

The DROP‐AD project: AD biomarkers from dry blood spots

Συγγραφείς: Huber, Hanna, Brum, Wagner Scheeren, Montoliu‐Gaya, Laia, Dittrich, Anna, Kern, Silke, Sander, Millie, Simonsen, Anja Hviid, Corbett, Anne, Fortea, Juan, Palmqvist, Sebastian, Borroni, Barbara, Hansson, Oskar, Boada, Mercè, Arús, Xavier Morató, Blennow, Kaj, Zetterberg, Henrik, Ashton, Nicholas J.

Πηγή: Alzheimers Dement

Θεματικοί όροι: Biomarkers

ApoE Genotyping and 12‐Month Longitudinal Tracking of p ‐Tau217 Using Fingerstick Collection in a Population‐Based Cohort

Συγγραφείς: Montoliu‐Gaya, Laia, Huber, Hanna, Blazquez, Josep, Braun‐Wohlfahrt, Luisa Sophie, Vávra, Jakub, Calm, Berta, Laia, Cañada, Cano, Amanda, Valero, Sergi, Fernández, Victoria, Blennow, Kaj, Zetterberg, Henrik, Boada, Mercè, Ashton, Nicholas, Arús, Xavier Morató

Πηγή: Alzheimers Dement

Θεματικοί όροι: Biomarkers

Pharmacodynamic and Clinical Effects of Ginkgo Biloba Extract EGb 761 and Its Phytochemical Components in Alzheimer’s Disease

Συγγραφείς: Xavier, Morató, Juan Pablo, Tartari, Vanesa, Pytel, Mercè, Boada

Πηγή: Advances in Alzheimer’s Disease ISBN: 9781643685311

Θεματικοί όροι: Plant Extracts, Alzheimer Disease, Ginkgo biloba, Humans, Animals, Ginkgo Extract, Phytotherapy

Σύνδεσμος πρόσβασης: https://pubmed.ncbi.nlm.nih.gov/39422946

Randomized phase 2a trial assessing a novel septin molecular glue in Alzheimer's disease

Συγγραφείς: Mieke Nuytten, Marieke Voets, Eveline Debroux, Katrien Princen, Lentel Pringels, Marc Fivaz, Eline Byl, Steven Ramael, Koen De Witte, Mercé Boada, Xavier Morató, Juan Pablo Tartari, Asunción Lafuente, Emilio Franco Macias, Jordi A. Matias‐Guiu, Everard Vijverberg, Charlotte E. Teunissen, Peter Anderer, Vincent Staggs, Vincent Hayman, Anne Corbett, Clive Ballard, John E. Harrison, Manfred Windisch, Ann Brinkmalm Westman, Henrik Zetterberg, Sam Dickson, Craig Mallinckrodt, Suzanne Hendrix, Jeffrey Cummings, Gerard Griffioen

Πηγή: Alzheimers Dement

Θεματικοί όροι: Male, Aged, 80 and over, disease-modification, neurodegeneration, AD, tau Proteins, Electroencephalography, Alzheimer's disease, calcium dyshomeostasis, Middle Aged, symptomatic benefit, amyloid-beta, molecular glue, Double-Blind Method, Alzheimer Disease, Humans, Female, tau, AD pathology, septin, phase 2a clinical trial, Septins, Biomarkers, Research Article, Aged

Σύνδεσμος πρόσβασης: https://pubmed.ncbi.nlm.nih.gov/40937833
https://pubmed.ncbi.nlm.nih.gov/40937833/
https://doi.org/10.1002/alz.70537
https://pmc.ncbi.nlm.nih.gov/articles/PMC12426855/