Diversity and spatial segregation of TRP channels in the closest relatives of animals.

Συγγραφείς: Mannsåker S; Michael Sars Centre, University of Bergen, Bergen 5006, Norway., Burkhardt P; Michael Sars Centre, University of Bergen, Bergen 5006, Norway., Colgren J; Michael Sars Centre, University of Bergen, Bergen 5006, Norway.

Πηγή: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2026 Oct 13; Vol. 123 (41), pp. e2625484123. Date of Electronic Publication: 2026 Oct 07.

Τύπος έκδοσης: Journal Article

Στοιχεία περιοδικού: Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1091-6490 (Electronic) Linking ISSN: 00278424 NLM ISO Abbreviation: Proc Natl Acad Sci U S A Subsets: MEDLINE

Ιατρικοί όροι (MeSH): Transient Receptor Potential Channels*/genetics , Transient Receptor Potential Channels*/metabolism , Choanoflagellata*/genetics , Choanoflagellata*/metabolism, Animals ; Phylogeny ; Evolution, Molecular ; Biological Evolution

Targeting lysosomal dysfunction with small-molecule TRPML1 ligands: Therapeutic opportunities in lysosomal storage disorders, neurodegeneration and beyond.

Συγγραφείς: Czuba M; Department of Medicinal Chemistry, Faculty of Pharmacy, Jagiellonian University Medical College, 9 Medyczna Street, Kraków, 30-688, Poland., Szafrańska K; Department of Medicinal Chemistry, Faculty of Pharmacy, Jagiellonian University Medical College, 9 Medyczna Street, Kraków, 30-688, Poland., Kolaczkowski M; Department of Medicinal Chemistry, Faculty of Pharmacy, Jagiellonian University Medical College, 9 Medyczna Street, Kraków, 30-688, Poland., Marcinkowska M; Department of Medicinal Chemistry, Faculty of Pharmacy, Jagiellonian University Medical College, 9 Medyczna Street, Kraków, 30-688, Poland. Electronic address: monika.marcinkowska@uj.edu.pl.

Πηγή: European journal of medicinal chemistry [Eur J Med Chem] 2026 Oct 05; Vol. 315, pp. 118951. Date of Electronic Publication: 2026 May 14.

Τύπος έκδοσης: Journal Article; Review

Στοιχεία περιοδικού: Publisher: Editions Scientifiques Elsevier Country of Publication: France NLM ID: 0420510 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1768-3254 (Electronic) Linking ISSN: 02235234 NLM ISO Abbreviation: Eur J Med Chem Subsets: MEDLINE

Ιατρικοί όροι (MeSH): Transient Receptor Potential Channels*/metabolism , Transient Receptor Potential Channels*/antagonists & inhibitors , Transient Receptor Potential Channels*/agonists , Neurodegenerative Diseases*/drug therapy , Neurodegenerative Diseases*/metabolism , Lysosomal Storage Diseases*/drug therapy , Lysosomal Storage Diseases*/metabolism , Small Molecule Libraries*/pharmacology , Small Molecule Libraries*/chemistry , Lysosomes*/drug effects , Lysosomes*/metabolism, Humans ; Ligands ; Animals ; Molecular Structure

Light-induced remodeling of the Drosophila phosphoproteome regulates visual adaptation through the Trp channel.

Συγγραφείς: Kramer LD; Department of Biochemistry, Purdue University, West Lafayette, IN 47907, USA., Brandwine-Shemmer T; Department of Medical Neurobiology Faculty of Medicine and Edmond and Lily Safra Center for Brain Sciences (ELSC), Hebrew University, Jerusalem, Israel., Pierce LR; Department of Biochemistry, Purdue University, West Lafayette, IN 47907, USA., Liu YK; Department of Biochemistry, Purdue University, West Lafayette, IN 47907, USA., Bartels JP; Institute of Biology, Department of Biochemistry, University of Hohenheim, 70599 Stuttgart, Germany., Huber A; Institute of Biology, Department of Biochemistry, University of Hohenheim, 70599 Stuttgart, Germany., Minke B; Department of Medical Neurobiology Faculty of Medicine and Edmond and Lily Safra Center for Brain Sciences (ELSC), Hebrew University, Jerusalem, Israel., Tao WA; Department of Biochemistry, Purdue University, West Lafayette, IN 47907, USA.; Purdue Center for Cancer Research, Purdue University, West Lafayette, IN 47907, USA.; Department of Chemistry, Purdue University, West Lafayette, IN 47907, USA., Weake VM; Department of Biochemistry, Purdue University, West Lafayette, IN 47907, USA.; Purdue Center for Cancer Research, Purdue University, West Lafayette, IN 47907, USA.

Πηγή: Science signaling [Sci Signal] 2026 Sep 29; Vol. 19 (957), pp. eaei4151. Date of Electronic Publication: 2026 Sep 29.

Τύπος έκδοσης: Journal Article

Στοιχεία περιοδικού: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101465400 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1937-9145 (Electronic) Linking ISSN: 19450877 NLM ISO Abbreviation: Sci Signal Subsets: MEDLINE

Ιατρικοί όροι (MeSH): Drosophila Proteins*/metabolism , Drosophila Proteins*/genetics , Phosphoproteins*/metabolism , Phosphoproteins*/genetics , Proteome*/metabolism , Transient Receptor Potential Channels*/metabolism , Transient Receptor Potential Channels*/genetics , Drosophila melanogaster*/metabolism , Adaptation, Ocular*/physiology , Light*, Phosphorylation/radiation effects ; Protein Kinase C/metabolism ; Animals ; Blue Light

Ion channel TRPML2 (MCOLN2) promotes ovarian cancer metastasis and chemoresistance.

Συγγραφείς: Yang S; Department of Obstetrics and Gynecology, Affiliated Hospital of Jiangnan University, Wuxi, Jiangsu, China. Electronic address: yangsz1986@126.cim., Lei Z; School of Biomedical Sciences, Heart and Vascular Institute and Li Ka Shing Institute of Health Sciences, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong, China., Yao X; School of Biomedical Sciences, Heart and Vascular Institute and Li Ka Shing Institute of Health Sciences, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong, China., Yu J; Department of Obstetrics and Gynecology, Affiliated Hospital of Jiangnan University, Wuxi, Jiangsu, China.

Πηγή: Biochemical and biophysical research communications [Biochem Biophys Res Commun] 2026 Sep 17; Vol. 831, pp. 154288. Date of Electronic Publication: 2026 Jul 14.

Τύπος έκδοσης: Journal Article

Στοιχεία περιοδικού: Publisher: Elsevier Country of Publication: United States NLM ID: 0372516 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1090-2104 (Electronic) Linking ISSN: 0006291X NLM ISO Abbreviation: Biochem Biophys Res Commun Subsets: MEDLINE

Ιατρικοί όροι (MeSH): Ovarian Neoplasms*/pathology , Ovarian Neoplasms*/metabolism , Ovarian Neoplasms*/drug therapy , Ovarian Neoplasms*/genetics , Transient Receptor Potential Channels*/metabolism , Transient Receptor Potential Channels*/genetics , Drug Resistance, Neoplasm*, Cell Movement/drug effects ; Carboplatin/pharmacology ; Antineoplastic Agents/pharmacology ; Cell Proliferation/drug effects ; Female ; Humans ; Cell Line, Tumor ; Neoplasm Metastasis ; Gene Expression Regulation, Neoplastic

Decreased Transient Receptor Potential Channel mRNA Expression in the Aortas of Patients with Hypertension.

Συγγραφείς: Dokumacı AD; Department of Medical Pharmacology, Faculty of Medicine, University of Gaziantep, Gaziantep, Türkiye., Alaşehirli B; Department of Medical Pharmacology, Faculty of Medicine, University of Gaziantep, Gaziantep, Türkiye., Balcıoğlu AS; Department of Cardiology, Faculty of Medicine, Kahramanmaraş Sütçü İmam University, Kahramanmaraş, Türkiye., Balcı SO; Department of Medical Biology, Faculty of Medicine, University of Gaziantep, Gaziantep, Türkiye., Eser N; Department of Medical Pharmacology, Faculty of Medicine, Kahramanmaraş Sütçü İmam University, Kahramanmaraş, Türkiye., Çelik İS; Department of Medical Services and Techniques, Kahramanmaraş Health Services Vocational School, Pathology Laboratory Techniques Pr., Kahramanmaraş Sütçü İmam University, Kahramanmaraş, Türkiye., Acıpayam M; Department of Cardiovascular Surgery, Faculty of Medicine, Kahramanmaraş Sütçü İmam University, Kahramanmaraş, Türkiye.

Πηγή: Anatolian journal of cardiology [Anatol J Cardiol] 2026 Sep 01; Vol. 29 (9), pp. 472-479. Date of Electronic Publication: 2025 May 29.

Τύπος έκδοσης: Journal Article

Στοιχεία περιοδικού: Publisher: KARE publishing Country of Publication: Turkey NLM ID: 101652981 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2149-2271 (Electronic) Linking ISSN: 21492263 NLM ISO Abbreviation: Anatol J Cardiol Subsets: MEDLINE

Ιατρικοί όροι (MeSH): Hypertension*/genetics , Hypertension*/metabolism , RNA, Messenger*/metabolism , RNA, Messenger*/genetics , Transient Receptor Potential Channels*/genetics , Transient Receptor Potential Channels*/metabolism , Aorta*/metabolism, Humans ; Male ; Female ; Middle Aged ; Case-Control Studies ; Aged ; Real-Time Polymerase Chain Reaction

Macrophage TRPML1 ameliorates post-myocardial infarction inflammation by blocking VDAC1 oligomerization to prevent ferroptosis and cGAS-STING activation.

Συγγραφείς: Zhao X; Institute of Clinical Pharmacology, The Second Affiliated Hospital of Harbin Medical University (National Key Laboratory of Frigid Cardiovascular Disease), Harbin, 150081, China., Wang J; Institute of Clinical Pharmacology, The Second Affiliated Hospital of Harbin Medical University (National Key Laboratory of Frigid Cardiovascular Disease), Harbin, 150081, China., Wang Z; Institute of Clinical Pharmacology, The Second Affiliated Hospital of Harbin Medical University (National Key Laboratory of Frigid Cardiovascular Disease), Harbin, 150081, China., Du H; Institute of Clinical Pharmacology, The Second Affiliated Hospital of Harbin Medical University (National Key Laboratory of Frigid Cardiovascular Disease), Harbin, 150081, China., Li H; Institute of Clinical Pharmacology, The Second Affiliated Hospital of Harbin Medical University (National Key Laboratory of Frigid Cardiovascular Disease), Harbin, 150081, China., Wu T; Institute of Clinical Pharmacology, The Second Affiliated Hospital of Harbin Medical University (National Key Laboratory of Frigid Cardiovascular Disease), Harbin, 150081, China., Yang K; Institute of Clinical Pharmacology, The Second Affiliated Hospital of Harbin Medical University (National Key Laboratory of Frigid Cardiovascular Disease), Harbin, 150081, China., Xie L; Institute of Clinical Pharmacology, The Second Affiliated Hospital of Harbin Medical University (National Key Laboratory of Frigid Cardiovascular Disease), Harbin, 150081, China., Zhang M; Institute of Clinical Pharmacology, The Second Affiliated Hospital of Harbin Medical University (National Key Laboratory of Frigid Cardiovascular Disease), Harbin, 150081, China., Wang J; Institute of Clinical Pharmacology, The Second Affiliated Hospital of Harbin Medical University (National Key Laboratory of Frigid Cardiovascular Disease), Harbin, 150081, China., Li P; Institute of Clinical Pharmacology, The Second Affiliated Hospital of Harbin Medical University (National Key Laboratory of Frigid Cardiovascular Disease), Harbin, 150081, China., Lv C; Institute of Clinical Pharmacology, The Second Affiliated Hospital of Harbin Medical University (National Key Laboratory of Frigid Cardiovascular Disease), Harbin, 150081, China., Deng Y; Institute of Clinical Pharmacology, The Second Affiliated Hospital of Harbin Medical University (National Key Laboratory of Frigid Cardiovascular Disease), Harbin, 150081, China., Ji H; Institute of Clinical Pharmacology, The Second Affiliated Hospital of Harbin Medical University (National Key Laboratory of Frigid Cardiovascular Disease), Harbin, 150081, China., Zhang Y; Institute of Clinical Pharmacology, The Second Affiliated Hospital of Harbin Medical University (National Key Laboratory of Frigid Cardiovascular Disease), Harbin, 150081, China., Li X; Institute of Clinical Pharmacology, The Second Affiliated Hospital of Harbin Medical University (National Key Laboratory of Frigid Cardiovascular Disease), Harbin, 150081, China., Yuan Y; Institute of Clinical Pharmacology, The Second Affiliated Hospital of Harbin Medical University (National Key Laboratory of Frigid Cardiovascular Disease), Harbin, 150081, China. Electronic address: yuany@hrbmu.edu.cn., Du Z; Institute of Clinical Pharmacology, The Second Affiliated Hospital of Harbin Medical University (National Key Laboratory of Frigid Cardiovascular Disease), Harbin, 150081, China; State Key Laboratory of Quality Research in Chinese Medicines, Macau University of Science and Technology, 999078, Macau. Electronic address: duzm@hrbmu.edu.cn.

Πηγή: Free radical biology & medicine [Free Radic Biol Med] 2026 Aug 16; Vol. 252, pp. 166-183. Date of Electronic Publication: 2026 May 04.

Τύπος έκδοσης: Journal Article

Στοιχεία περιοδικού: Publisher: Elsevier Science Country of Publication: United States NLM ID: 8709159 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-4596 (Electronic) Linking ISSN: 08915849 NLM ISO Abbreviation: Free Radic Biol Med Subsets: MEDLINE

Ιατρικοί όροι (MeSH): cGAS-STING Signaling Pathway*/immunology , Ferroptosis*/immunology , Macrophages*/metabolism , Macrophages*/pathology , Myocardial Infarction*/genetics , Myocardial Infarction*/immunology , Myocardial Infarction*/metabolism , Myocardial Infarction*/pathology , Transient Receptor Potential Channels*/metabolism , Transient Receptor Potential Channels*/genetics , Voltage-Dependent Anion Channel 1*/metabolism , Voltage-Dependent Anion Channel 1*/genetics, Cyclic Guanosine Monophosphate-Adenosine Monophosphate Synthase/metabolism ; Inflammation/pathology ; Inflammation/metabolism ; Inflammation/genetics ; Myocytes, Cardiac/metabolism ; STING Protein/metabolism ; Animals ; Male ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; Oxidative Stress

TFEB and MCOLN1 are important for Coxiella burnetii egress via lysosomal exocytosis.

Συγγραφείς: Rinkel S; Mikrobiologisches Institut, Universitätsklinikum Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany., Schulze-Luehrmann J; Mikrobiologisches Institut, Universitätsklinikum Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany., Kadavil Baburaj B; Mikrobiologisches Institut, Universitätsklinikum Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany., Weber F; Mikrobiologisches Institut, Universitätsklinikum Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany., Liebler-Tenorio EM; Friedrich-Loeffler-Institut, Institut für Molekulare Pathogenese, Jena, Germany., Lührmann A; Mikrobiologisches Institut, Universitätsklinikum Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany.

Πηγή: Frontiers in cellular and infection microbiology [Front Cell Infect Microbiol] 2026 Aug 14; Vol. 16, pp. 1835140. Date of Electronic Publication: 2026 Aug 14 (Print Publication: 2026).

Τύπος έκδοσης: Journal Article

Στοιχεία περιοδικού: Publisher: Frontiers Media SA Country of Publication: Switzerland NLM ID: 101585359 Publication Model: eCollection Cited Medium: Internet ISSN: 2235-2988 (Electronic) Linking ISSN: 22352988 NLM ISO Abbreviation: Front Cell Infect Microbiol Subsets: MEDLINE

Ιατρικοί όροι (MeSH): Coxiella burnetii*/physiology , Coxiella burnetii*/pathogenicity , Lysosomes*/metabolism , Lysosomes*/microbiology , Transient Receptor Potential Channels*/metabolism , Transient Receptor Potential Channels*/genetics , Basic Helix-Loop-Helix Leucine Zipper Transcription Factors*/metabolism , Basic Helix-Loop-Helix Leucine Zipper Transcription Factors*/genetics , Q Fever*/microbiology , Q Fever*/metabolism , Exocytosis*, Vacuoles/microbiology ; Vacuoles/metabolism ; Calcium/metabolism ; Animals ; Humans ; Host-Pathogen Interactions ; Autophagy

Transient Receptor Potential Channel Signaling in Hypertension: Mechanisms, Translation, and Therapeutic Targeting.

Μεταγλωττισμένος Τίτλος: Geçici Reseptör Potansiyel Kanal Sinyal İletimi ve Hipertansiyon: Mekanizmalar, Translasyon ve Terapötik Hedefleme.

Συγγραφείς: Dokumacı AD; Department of Medical Pharmacology, Faculty of Medicine, Kahramanmaraş Sütçü İmam University, Kahramanmaraş, Türkiye., Alaşehirli B; Department of Medical Pharmacology, Faculty of Medicine, Gaziantep University, Gaziantep, Türkiye., Balcıoğlu AS; Department of Cardiology, Faculty of Medicine, Kahramanmaraş Sütçü İmam University, Kahramanmaraş, Türkiye.

Πηγή: Turk Kardiyoloji Dernegi arsivi : Turk Kardiyoloji Derneginin yayin organidir [Turk Kardiyol Dern Ars] 2026 Aug 14; Vol. 54 (6), pp. 463-470. Date of Electronic Publication: 2026 Apr 10.

Τύπος έκδοσης: Journal Article; Review

Στοιχεία περιοδικού: Publisher: Kare Country of Publication: Turkey NLM ID: 9426239 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1308-4488 (Electronic) Linking ISSN: 10165169 NLM ISO Abbreviation: Turk Kardiyol Dern Ars Subsets: MEDLINE

Ιατρικοί όροι (MeSH): Hypertension*/physiopathology , Hypertension*/drug therapy , Hypertension*/metabolism , Transient Receptor Potential Channels*/metabolism , Transient Receptor Potential Channels*/physiology , Signal Transduction*, Humans ; Animals

Transient Receptor Potential (TRP) channels: Quantitative biophysical correlates of cognitive function across brain regions.

Συγγραφείς: Woodard GE; Department of Psychiatry, Uniformed Services of the Health Sciences, Bethesda, MD 20814, United States. Electronic address: gew232000@gmail.com., Julien C; Department of Medicine, Keck School of Medicine of USC, Los Angeles, CA 90033, United States.

Πηγή: Behavioural brain research [Behav Brain Res] 2026 Aug 05; Vol. 511, pp. 116267. Date of Electronic Publication: 2026 May 22.

Τύπος έκδοσης: Journal Article; Review

Στοιχεία περιοδικού: Publisher: Elsevier/North-Holland Biomedical Press Country of Publication: Netherlands NLM ID: 8004872 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1872-7549 (Electronic) Linking ISSN: 01664328 NLM ISO Abbreviation: Behav Brain Res Subsets: MEDLINE

Ιατρικοί όροι (MeSH): Brain*/metabolism , Brain*/physiology , Cognition*/physiology , Transient Receptor Potential Channels*/metabolism , Transient Receptor Potential Channels*/physiology, Neuronal Plasticity/physiology ; Animals ; Humans

Sensing Underwater: Diversifying Selection, Convergent Evolution and Inactivation in Sensory Receptors' Genes of Aquatic Mammals.

Συγγραφείς: Lein-Borba AL; Department of Genetics, Evolution, Microbiology and Immunology, University of Campinas, Campinas, SP, Brazil. analuizaclein@gmail.com., Selleghin-Veiga G; Department of Genetics, Evolution, Microbiology and Immunology, University of Campinas, Campinas, SP, Brazil., Daros B; Department of Genetics, Evolution, Microbiology and Immunology, University of Campinas, Campinas, SP, Brazil., Magpali L; Department of Biology, Dalhousie University, Halifax, NS, Canada., Nery MF; Department of Genetics, Evolution, Microbiology and Immunology, University of Campinas, Campinas, SP, Brazil. marinery@unicamp.br.

Πηγή: Journal of molecular evolution [J Mol Evol] 2026 Aug; Vol. 94 (4), pp. 629-654. Date of Electronic Publication: 2026 Jul 01.

Τύπος έκδοσης: Journal Article

Στοιχεία περιοδικού: Publisher: Springer-Verlag Country of Publication: Germany NLM ID: 0360051 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-1432 (Electronic) Linking ISSN: 00222844 NLM ISO Abbreviation: J Mol Evol Subsets: MEDLINE

Ιατρικοί όροι (MeSH): Transient Receptor Potential Channels*/genetics , Cetacea*/genetics , Evolution, Molecular* , Selection, Genetic*, Sirenia/genetics ; Mammals/genetics ; Animals ; Phylogeny ; Amino Acid Substitution ; Amino Acid Sequence

Pathological roles of transient receptor potential channels in chronic obstructive pulmonary disease: special focus on cellular mechanisms.

Συγγραφείς: Ye YR; School of Life Sciences, Sun Yat-Sen University, Guangzhou, P. R. China., Zhou YY; School of Life Sciences, Sun Yat-Sen University, Guangzhou, P. R. China., Qu S; School of Life Sciences, Sun Yat-Sen University, Guangzhou, P. R. China., Zhou WL; School of Life Sciences, Sun Yat-Sen University, Guangzhou, P. R. China., Chen L; State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, National Center for Respiratory Medicine, Guangzhou Institute of Respiratory Health, the First Affiliated Hospital, Guangzhou Medical University, Guangzhou, P. R. China., Zhang YL; School of Life Sciences, Sun Yat-Sen University, Guangzhou, P. R. China.; Guangdong Engineering and Technology Research Center for Quality and Efficacy Re-evaluation of Post-marketed TCM, Guangdong Province Key Laboratory of Pharmaceutical Functional Genes, School of Life Sciences, Sun Yat-Sen University, Guangzhou, P. R. China.

Πηγή: Expert review of respiratory medicine [Expert Rev Respir Med] 2026 Aug; Vol. 20 (8), pp. 953-962. Date of Electronic Publication: 2026 Mar 30.

Τύπος έκδοσης: Journal Article; Review

Στοιχεία περιοδικού: Publisher: Taylor & Francis Country of Publication: England NLM ID: 101278196 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1747-6356 (Electronic) Linking ISSN: 17476348 NLM ISO Abbreviation: Expert Rev Respir Med Subsets: MEDLINE

Ιατρικοί όροι (MeSH): Pulmonary Disease, Chronic Obstructive*/physiopathology , Pulmonary Disease, Chronic Obstructive*/drug therapy , Transient Receptor Potential Channels*/metabolism, Humans ; Animals

Integrative screening of plant volatiles through transient receptor potential channel docking, olfactometry, and field validation in Bemisia tabaci.

Συγγραφείς: Paschapur AU; ICAR-Vivekananda Parvatiya Krishi Anusandhan Sansthan, Almora, India.; Division of Entomology, ICAR-Indian Agricultural Research Institute, New Delhi, India., Pandey D; Division of Entomology, ICAR-Indian Agricultural Research Institute, New Delhi, India., Singh L; Centre for Protected Cultivation Technology, ICAR-Indian Agricultural Research Institute, New Delhi, India., Marella SM; Division of Entomology, ICAR-Indian Agricultural Research Institute, New Delhi, India., Nebapure SM; Division of Entomology, ICAR-Indian Agricultural Research Institute, New Delhi, India., Subramanian S; Division of Entomology, ICAR-Indian Agricultural Research Institute, New Delhi, India.

Πηγή: Pest management science [Pest Manag Sci] 2026 Aug; Vol. 82 (8), pp. 7463-7482. Date of Electronic Publication: 2026 Apr 16.

Τύπος έκδοσης: Journal Article

Στοιχεία περιοδικού: Publisher: Published for SCI by Wiley Country of Publication: England NLM ID: 100898744 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1526-4998 (Electronic) Linking ISSN: 1526498X NLM ISO Abbreviation: Pest Manag Sci Subsets: MEDLINE

Ιατρικοί όροι (MeSH): Volatile Organic Compounds*/chemistry , Volatile Organic Compounds*/pharmacology , Transient Receptor Potential Channels*/metabolism , Transient Receptor Potential Channels*/chemistry , Transient Receptor Potential Channels*/genetics , Hemiptera*/physiology , Hemiptera*/drug effects , Insect Proteins*/metabolism , Insect Proteins*/chemistry , Insect Proteins*/genetics , Plants*/chemistry, Insect Control/methods ; Animals ; Molecular Docking Simulation ; Olfactometry ; RNA Interference

Transient receptor potential channel activation targets multiple stages of the schistosome parasite.

Συγγραφείς: Kulkarni S; EMD Serono Research and Development Institute Inc. (a Business of Merck KGaA., Darmstadt, Germany), Billerica, MA, USA., Park SK; Department of Cell Biology, Neurobiology and Anatomy, Medical College of Wisconsin, Milwaukee, WI, USA., Hamway Y; Institute for Medical Microbiology, Immunology and Hygiene, Technical University of Munich, Munich, Germany.; Center for Global Health, TUM School of Medicine, Technical University of Munich, Munich, Germany.; German Center for Infection and Research (DZIF), Partner site Munich, Munich, Germany., Friedrich L; Computational Chemistry and Biology, Global Research and Development, Discovery Technologies, the Healthcare Business of Merck KGaA, Darmstadt, Germany., Kaiser J; Computational Chemistry and Biology, Global Research and Development, Discovery Technologies, the Healthcare Business of Merck KGaA, Darmstadt, Germany., Chulkov EG; Department of Cell Biology, Neurobiology and Anatomy, Medical College of Wisconsin, Milwaukee, WI, USA., Rohr CM; Department of Cell Biology, Neurobiology and Anatomy, Medical College of Wisconsin, Milwaukee, WI, USA., Häberli C; Universität Basel, Basel, Switzerland.; Swiss Tropical and Public Health Institute, Allschwil, Switzerland., Horn M; Institute of Organic Chemistry and Biochemistry, Czech Academy of Sciences, Prague, Czechia., Bäurle THH; Site Management-Analytics, Merck Healthcare KGaA, Darmstadt, Germany., Pellegatti M; External consultant, Verona, Italy., Grosser G; Chemical and Preclinical Safety, Merck Healthcare KGaA, Darmstadt, Germany., Becker A; Site Management-Analytics, Merck Healthcare KGaA, Darmstadt, Germany., Afshar R; Global Health R&D of the Healthcare Business of Merck KGaA, Darmstadt, Germany, Ares Trading S.A. (an affiliate of Merck KGaA, Darmstadt, Germany), Eysins, Switzerland., Becker A; Translational Medicine, Quantitative Pharmacology, the Healthcare Business of Merck KGaA, Darmstadt, Germany., Mell NA; Global Healthcare Operations, Global CMC Development, Merck Healthcare KGaA, Darmstadt, Germany., Lignet F; Drug Discovery Technologies, the Healthcare Business of Merck KGaA, Darmstadt, Germany., Hewitt P; Chemical and Preclinical Safety, Merck Healthcare KGaA, Darmstadt, Germany., Hansen A; Chemical and Preclinical Safety, Merck Healthcare KGaA, Darmstadt, Germany., Brenneis C; Chemical and Preclinical Safety, Merck Healthcare KGaA, Darmstadt, Germany., Dvorak J; Institute of Organic Chemistry and Biochemistry, Czech Academy of Sciences, Prague, Czechia.; Department of Ecology, Center of Infectious Animal Diseases, Faculty of Environmental Sciences, Czech University of Life Sciences, Prague, Czechia., da Costa CP; Institute for Medical Microbiology, Immunology and Hygiene, Technical University of Munich, Munich, Germany.; Center for Global Health, TUM School of Medicine, Technical University of Munich, Munich, Germany.; German Center for Infection and Research (DZIF), Partner site Munich, Munich, Germany., Keiser J; Universität Basel, Basel, Switzerland.; Swiss Tropical and Public Health Institute, Allschwil, Switzerland., Marchant JS; Department of Cell Biology, Neurobiology and Anatomy, Medical College of Wisconsin, Milwaukee, WI, USA., Spangenberg T; Global Health R&D of the Healthcare Business of Merck KGaA, Darmstadt, Germany, Ares Trading S.A. (an affiliate of Merck KGaA, Darmstadt, Germany), Eysins, Switzerland.

Πηγή: Science translational medicine [Sci Transl Med] 2026 Oct 07; Vol. 18 (870), pp. eaed8353. Date of Electronic Publication: 2026 Oct 07.

Τύπος έκδοσης: Journal Article

Στοιχεία περιοδικού: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101505086 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1946-6242 (Electronic) Linking ISSN: 19466234 NLM ISO Abbreviation: Sci Transl Med Subsets: MEDLINE

Ιατρικοί όροι (MeSH): Transient Receptor Potential Channels*/metabolism , Life Cycle Stages*/drug effects , Schistosoma mansoni*/drug effects , Schistosoma mansoni*/growth & development , Schistosoma mansoni*/metabolism , Schistosoma*/drug effects, Praziquantel/pharmacology ; Praziquantel/therapeutic use ; Prodrugs/pharmacology ; Prodrugs/chemistry ; Animals ; Mice ; Humans

TRP channel activation and cholinergic signaling in insect thermoregulation: evidence from the American cockroach.

Συγγραφείς: Maliszewska J; Department of Animal Physiology and Neurobiology, Faculty of Biological and Veterinary Sciences, Nicolaus Copernicus University, Lwowska 1, Toruń, 87-100, Poland. ojustyna@umk.pl., Jankowska M; Department of Animal Physiology and Neurobiology, Faculty of Biological and Veterinary Sciences, Nicolaus Copernicus University, Lwowska 1, Toruń, 87-100, Poland., Artkop M; Department of Pathophysiology, Faculty of Pharmacy, Ludwik Rydygier Collegium Medicum, Nicolaus Copernicus University in Toruń, Bydgoszcz, 85-094, Poland., Rogalska J; Department of Animal Physiology and Neurobiology, Faculty of Biological and Veterinary Sciences, Nicolaus Copernicus University, Lwowska 1, Toruń, 87-100, Poland.

Πηγή: Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology [J Comp Physiol B] 2026 Oct; Vol. 196 (5), pp. 621-631. Date of Electronic Publication: 2026 Jul 27.

Τύπος έκδοσης: Journal Article

Στοιχεία περιοδικού: Publisher: Springer-Verlag Country of Publication: Germany NLM ID: 8413200 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-136X (Electronic) Linking ISSN: 01741578 NLM ISO Abbreviation: J Comp Physiol B Subsets: MEDLINE

Ιατρικοί όροι (MeSH): Periplaneta*/physiology , Periplaneta*/drug effects , Body Temperature Regulation*/physiology , Body Temperature Regulation*/drug effects , Transient Receptor Potential Channels*/metabolism , Receptors, Nicotinic*/metabolism, Capsaicin/pharmacology ; Capsaicin/analogs & derivatives ; Neurons/drug effects ; Neurons/physiology ; TRPV Cation Channels/antagonists & inhibitors ; TRPV Cation Channels/metabolism ; Animals ; Signal Transduction ; Male

Airway sensory neurobiology and TRP channels in chronic cough: mechanisms, cough hypersensitivity, and therapeutic translation.

Συγγραφείς: Yang X; Institute of Medical Research, Northwestern Polytechnical University, 127 West Youyi Road, Xi'an, Shaanxi, 710072, China. Electronic address: yangxinyue@mail.nwpu.edu.cn., Duan X; Institute of Medical Research, Northwestern Polytechnical University, 127 West Youyi Road, Xi'an, Shaanxi, 710072, China. Electronic address: duanxianglong@nwpu.edu.cn.

Πηγή: Life sciences [Life Sci] 2026 Sep 15; Vol. 401, pp. 124499. Date of Electronic Publication: 2026 May 28.

Τύπος έκδοσης: Journal Article; Review

Στοιχεία περιοδικού: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 0375521 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-0631 (Electronic) Linking ISSN: 00243205 NLM ISO Abbreviation: Life Sci Subsets: MEDLINE

Ιατρικοί όροι (MeSH): Chronic Cough*/physiopathology , Chronic Cough*/metabolism , Chronic Cough*/drug therapy , Transient Receptor Potential Channels*/metabolism , Cough*/physiopathology , Cough*/metabolism, TRPV Cation Channels/metabolism ; Sensory Receptor Cells/metabolism ; Humans ; Animals ; Chronic Disease

Investigation and validation of prognostic features associated with transient receptor potential channel genes in gastric cancer.

Συγγραφείς: Zhao J; Department of Radiotherapye, The Second Hospital of Lanzhou University, Lanzhou, China.; Department of Oncology, The Second Hospital & Clinical Medical School, Lanzhou University, Lanzhou City, Gansu Province, China., Kang H; Department of Radiotherapye, The Second Hospital of Lanzhou University, Lanzhou, China., Pan J; Department of General Surgery, The Second Hospital of Lanzhou University, Lanzhou, China., Sun P; Department of Radiotherapye, The Second Hospital of Lanzhou University, Lanzhou, China.

Πηγή: PeerJ [PeerJ] 2026 Aug 11; Vol. 14, pp. e21468. Date of Electronic Publication: 2026 Aug 11 (Print Publication: 2026).

Τύπος έκδοσης: Journal Article

Στοιχεία περιοδικού: Publisher: PeerJ Inc Country of Publication: United States NLM ID: 101603425 Publication Model: eCollection Cited Medium: Internet ISSN: 2167-8359 (Electronic) Linking ISSN: 21678359 NLM ISO Abbreviation: PeerJ Subsets: MEDLINE

Ιατρικοί όροι (MeSH): Stomach Neoplasms*/genetics , Stomach Neoplasms*/pathology , Stomach Neoplasms*/mortality , Transient Receptor Potential Channels*/genetics , Adenocarcinoma*/genetics, Biomarkers, Tumor/genetics ; Humans ; Prognosis ; Gene Expression Regulation, Neoplastic ; Gene Regulatory Networks

HIV-1 gp120-induced lysosomal stress responses are controlled by TRPML1 redox sensors.

Συγγραφείς: Kumar N; Department of Biomedical Sciences, University of North Dakota School of Medicine and Health Sciences, Grand Forks, ND, USA.; Department of Neuroscience and Cell Biology, Rutgers University Robert Wood Johnson Medical School, Piscataway, NJ, USA., Liang B; Department of Biomedical Sciences, University of North Dakota School of Medicine and Health Sciences, Grand Forks, ND, USA., Geiger JD; Department of Biomedical Sciences, University of North Dakota School of Medicine and Health Sciences, Grand Forks, ND, USA.

Πηγή: Redox report : communications in free radical research [Redox Rep] 2026 Dec 31; Vol. 31 (1), pp. 2679333. Date of Electronic Publication: 2026 Jun 26.

Τύπος έκδοσης: Journal Article

Στοιχεία περιοδικού: Publisher: Taylor & Francis Country of Publication: England NLM ID: 9511366 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1743-2928 (Electronic) Linking ISSN: 13510002 NLM ISO Abbreviation: Redox Rep Subsets: MEDLINE

Ιατρικοί όροι (MeSH): HIV Envelope Protein gp120*/metabolism , Lysosomes*/metabolism , Transient Receptor Potential Channels*/metabolism , Transient Receptor Potential Channels*/genetics, Reactive Oxygen Species/metabolism ; Glutathione/metabolism ; HIV-1/metabolism ; Iron/metabolism ; Humans ; Oxidation-Reduction ; Cell Line, Tumor ; Oxidative Stress

Transient receptor potential channels in Flaviviridae infection: A comprehensive review.

Συγγραφείς: Jiang F; School of Pharmaceutical Science and Yunnan Key Laboratory of Pharmacology for Natural Products, Kunming Medical University, Kunming, China., Yao X; School of Biomedical Sciences and Li Ka Shing Institute of Health Science, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong, China., Zheng CB; School of Pharmaceutical Science and Yunnan Key Laboratory of Pharmacology for Natural Products, Kunming Medical University, Kunming, China.; Yunnan Key Laboratory of Cross-Border Infectious Disease Control and Prevention and Novel Drug Development, China.

Πηγή: Channels (Austin, Tex.) [Channels (Austin)] 2026 Dec; Vol. 20 (1), pp. 2665540. Date of Electronic Publication: 2026 May 05.

Τύπος έκδοσης: Journal Article; Review; Research Support, Non-U.S. Gov't

Στοιχεία περιοδικού: Publisher: Taylor & Francis Country of Publication: United States NLM ID: 101321614 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1933-6969 (Electronic) Linking ISSN: 19336950 NLM ISO Abbreviation: Channels (Austin) Subsets: MEDLINE

Ιατρικοί όροι (MeSH): Transient Receptor Potential Channels*/metabolism , Flaviviridae Infections*/metabolism , Flaviviridae Infections*/virology , Flaviviridae*/physiology , Flaviviridae*/metabolism, Humans ; Animals

Hispidulin ameliorates androgenetic alopecia by inhibiting dermal papilla cell ferroptosis via TRPML1 channel activation.

Συγγραφείς: Jin X; Zhejiang University School of Medicine, Department of Dermatology, Hangzhou Third People's Hospital, Affiliated Hangzhou Dermatology Hospital, Hangzhou, China., Zhang H; Department of Dermatology, Hangzhou Third People's Hospital, Affiliated Hangzhou Dermatology Hospital, Hangzhou, China., Shi Y; Zhejiang Chinese Medical University, Department of Dermatology, Hangzhou Third People's Hospital, Hangzhou, Zhejiang Province, China., Wei D; Department of Dermatology, Beijing Friendship Hospital, Capital Medical University, Beijing, China., Xu W; Department of Dermatology, Hangzhou Third People's Hospital, Affiliated Hangzhou Dermatology Hospital, Hangzhou, China., Fu S; Zhejiang Chinese Medical University, Department of Dermatology, Hangzhou Third People's Hospital, Hangzhou, Zhejiang Province, China., Chen H; Department of Orthopaedic Surgery, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, China; Key Laboratory of Musculoskeletal System Degeneration and Regeneration Translational Research of Zhejiang Province, Hangzhou, China., Song X; Zhejiang University School of Medicine, Department of Dermatology, Hangzhou Third People's Hospital, Affiliated Hangzhou Dermatology Hospital, Hangzhou, China. Electronic address: songxiuzu@sina.com.

Πηγή: Free radical biology & medicine [Free Radic Biol Med] 2026 Nov; Vol. 255, pp. 519-535. Date of Electronic Publication: 2026 Jul 27.

Τύπος έκδοσης: Journal Article

Στοιχεία περιοδικού: Publisher: Elsevier Science Country of Publication: United States NLM ID: 8709159 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-4596 (Electronic) Linking ISSN: 08915849 NLM ISO Abbreviation: Free Radic Biol Med Subsets: MEDLINE

Ιατρικοί όροι (MeSH): Alopecia*/drug therapy , Alopecia*/pathology , Alopecia*/metabolism , Alopecia*/chemically induced , Ferroptosis*/drug effects , Flavones*/pharmacology , Transient Receptor Potential Channels*/metabolism , Transient Receptor Potential Channels*/genetics , Dermis*/drug effects , Dermis*/metabolism , Dermis*/pathology, Hair Follicle/drug effects ; Hair Follicle/metabolism ; Hair Follicle/pathology ; Dihydrotestosterone/toxicity ; Oxidative Stress/drug effects ; Animals ; Mice ; Humans ; Male ; Molecular Docking Simulation ; Disease Models, Animal ; Mice, Inbred C57BL

Genome-wide identification and temperature-responsive expression profiling of TRP gene family in red swamp crayfish (Procambarus clarkii).

Συγγραφείς: Yang B; Key Laboratory of Freshwater Aquatic Genetic Resources, Ministry of Agriculture and Rural Affairs, Shanghai Ocean University, Shanghai, 201306, China., Ma Y; Key Laboratory of Freshwater Aquatic Genetic Resources, Ministry of Agriculture and Rural Affairs, Shanghai Ocean University, Shanghai, 201306, China., Bai Z; Key Laboratory of Freshwater Aquatic Genetic Resources, Ministry of Agriculture and Rural Affairs, Shanghai Ocean University, Shanghai, 201306, China., Wang Q; Key Laboratory of Freshwater Aquatic Genetic Resources, Ministry of Agriculture and Rural Affairs, Shanghai Ocean University, Shanghai, 201306, China., Liu C; Key Laboratory of Freshwater Aquatic Genetic Resources, Ministry of Agriculture and Rural Affairs, Shanghai Ocean University, Shanghai, 201306, China., Jia L; Key Laboratory of Freshwater Aquatic Genetic Resources, Ministry of Agriculture and Rural Affairs, Shanghai Ocean University, Shanghai, 201306, China. ljia@shou.edu.cn.; Shanghai Collaborative Innovation Center for Cultivating Elite Breeds and Green-Culture of Aquaculture Animals, Shanghai, 201306, China. ljia@shou.edu.cn., Bai Z; Key Laboratory of Freshwater Aquatic Genetic Resources, Ministry of Agriculture and Rural Affairs, Shanghai Ocean University, Shanghai, 201306, China. zybai@shou.edu.cn.; Shanghai Collaborative Innovation Center for Cultivating Elite Breeds and Green-Culture of Aquaculture Animals, Shanghai, 201306, China. zybai@shou.edu.cn.

Πηγή: BMC genomics [BMC Genomics] 2026 Jun 12; Vol. 27 (1). Date of Electronic Publication: 2026 Jun 12.

Τύπος έκδοσης: Journal Article

Στοιχεία περιοδικού: Publisher: BioMed Central Country of Publication: England NLM ID: 100965258 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-2164 (Electronic) Linking ISSN: 14712164 NLM ISO Abbreviation: BMC Genomics Subsets: MEDLINE

Ιατρικοί όροι (MeSH): Astacoidea*/genetics , Transient Receptor Potential Channels*/genetics , Transient Receptor Potential Channels*/metabolism , Gene Expression Profiling* , Multigene Family* , Temperature*, Animals ; Phylogeny ; Transcriptome ; Alternative Splicing