Predicting and understanding treatment response in infectious and oncological diseases using transcriptomic data and computational approaches

Authors: García Illarramendi, Juan Manuel

Thesis Advisors: Farrés i Marisch, Judith, Daura i Ribera, Xavier

Source: TDX (Tesis Doctorals en Xarxa)

Subject Terms: Biologia de Sistemes, Systems Biology, Biología de Sistemas, Transcriptòmica, Transcriptomics, Transcriptómica, Biomarcadors, Biomarkers, Biomarcadores, Ciències de la Salut

File Description: application/pdf

Access URL: http://hdl.handle.net/10803/695972

Spatial hallmarks of cancer: blueprinting precision oncology in MIBC and beyond

Authors: Sibai, Mustafa

Thesis Advisors: Porta Pardo, Eduard, Lorenzo Rivera, Julia

Source: TDX (Tesis Doctorals en Xarxa)

Subject Terms: Transcriptòmica espacial, Spatial transcriptomics, Transcriptómica espacial, Característiques distintives d, Cancer hallmarks, Características distintivas de, Oncologia de precisió, Precision oncology, Oncología de precisión, Ciències de la Salut

File Description: application/pdf

Access URL: http://hdl.handle.net/10803/695955

Clinical and molecular factors associated with allergic contact dermatitis

Authors: Pesque Cela, David

Thesis Advisors: Giménez Arnau, Ana M. (Ana María), 1961-, Pujol Vallverdú, Ramón M.

Source: TDX (Tesis Doctorals en Xarxa)

Subject Terms: Dermatitis de contacte, Contact dermatitis, Dermatitis de contacto, Factors de risc, Risk factors, Factores de riesgo, Transcriptòmica, Transcriptomics, Transcriptómica, Ciències de la Salut

File Description: application/pdf

Access URL: http://hdl.handle.net/10803/695554

Phosphate as a molecular switch in growth–immunity tradeoffs: Insights via phosphite treatment, gene editing, and biosensing

Authors: Mallavarapu, Mani Deepika

Thesis Advisors: San Segundo de los Mozos, Blanca

Source: TDX (Tesis Doctorals en Xarxa)

Subject Terms: Edició genètica CRISPR-Cas9, Gene Editing CRISPR-Cas9, Edición genética CRISPR-Cas9, Biosensors FRET, FRET Biosensors, Biosensores FRET, Transcriptòmica, Transcriptomics, Transcriptómica, Ciències Experimentals

File Description: application/pdf

Access URL: http://hdl.handle.net/10803/695155

Unraveling genetic and molecular mechanisms of cardiovascular diseases: insights from genomic and transcriptomic approaches

Authors: Temprano Sagrera, Gerard

Thesis Advisors: Sabater Leal, Maria, Barbadilla Prados, Antonio

Source: TDX (Tesis Doctorals en Xarxa)

Subject Terms: Genòmica, Genomics, Genómica, Transcriptòmica, Transcriptomics, Transcriptómica, Malalties cardiovasculars, Cardiovascular diseases, Enfermedades cardiovasculares, Ciències de la Salut

File Description: application/pdf

Access URL: http://hdl.handle.net/10803/694131

Genetic determinants orchestrating transcriptome regulation: nonsense-mediated mRNA decay and allele-specific expression variability in phenotypic diversity

Authors: Palou Márquez, Guillermo

Contributors: University/Department: Universitat Pompeu Fabra. Departament de Medicina i Ciències de la Vida

Thesis Advisors: Supek, Fran

Source: TDX (Tesis Doctorals en Xarxa)

Subject Terms: Allele-specific expression, Nonsense-mediated mRNA decay, Cancer transcriptomics, Genetic variants, Tumor evolution, Expresión específica de alelos, Degradación del ARN mensajero mediada por mutación terminadora, Transcriptómica del cáncer, Variantes genéticas, Evolución tumoral

File Description: application/pdf

Access URL: http://hdl.handle.net/10803/693611

Neuron-type molecular pathways underlying hippocampal-dependent memory deficits in Alzheimer's disease transgenic mice

Authors: Deprada Fernández, Ángel

Thesis Advisors: Parra Damas, Arnaldo Javier, Saura Antolín, Carlos A. (Carlos Alberto)

Source: TDX (Tesis Doctorals en Xarxa)

Subject Terms: Alzheimer, Transcriptòmica, Transcriptomics, Transcriptómica, Neurones inhibitories, Inhibitory neurons, Neuronas inhibitorias, Ciències Experimentals

File Description: application/pdf

Access URL: http://hdl.handle.net/10803/693075

Estudi del transcriptoma de l’Escherichia coli adherent-invasiva (AIEC) per desxifrar les bases moleculars implicades en la seva patogenicitat

Authors: Bonet-Rossinyol, Queralt

Contributors: University/Department: Universitat de Girona. Departament de Biologia

Thesis Advisors: Martínez Medina, Margarita

Source: TDX (Tesis Doctorals en Xarxa)

Subject Terms: Malaltia de Crohn, Enfermedad de Crohn, Crohn's disease, Escherichia coli adherent-invasiva, Escherichia coli adherente-invasivo, Adherent-invasive Escherichia coli, Arginina, Arginine, Àcid colànic, Ácido colánico, Colanic acid, Transcriptòmica comparativa, Transcriptómica comparativa, Comparative transcriptomics, Biomarcadors, Biomarcadores, Biomarkers

Time: 616.3

File Description: application/pdf

Access URL: http://hdl.handle.net/10803/692407

Al modelling of real-world patients: applications in prostate cancer

Authors: Matos-Filipe, Pedro

Contributors: University/Department: Universitat Pompeu Fabra. Departament de Medicina i Ciències de la Vida

Thesis Advisors: Oliva Miguel, Baldomero, Mas, José Manuel

Source: TDX (Tesis Doctorals en Xarxa)

Subject Terms: Microarrays, OMICs Integration, Transcriptomics, Prostate cancer, Biomarkers, Micromatrices, Integració d'òmiques, Transcriptòmica, Càncer de pròstata, Biomarcadors

Time: 616.6

File Description: application/pdf

Access URL: http://hdl.handle.net/10803/692488

Modeling cell type evolution using single-cell and chromatin profiling approaches

Authors: Elek, Anamaria

Contributors: University/Department: Universitat Pompeu Fabra. Departament de Medicina i Ciències de la Vida

Thesis Advisors: Sebé-Pedrós, Arnau

Source: TDX (Tesis Doctorals en Xarxa)

Subject Terms: Evolution, Genomics, Animal diversity, Gene regulation, Transcriptomics, Evolució, Genòmica, Diversitat animal, Regulació gènica, Transcriptòmica

File Description: application/pdf

Access URL: http://hdl.handle.net/10803/690731

Effect of brain DDR1 transcript expression and genetic variants on the diagnosis, neurocognitive performance and psychosocial functioning of patients with schizophrenia and bipolar disorder

Authors: Aranda Castel, Selena

Contributors: University/Department: Universitat Rovira i Virgili. Departament de Medicina i Cirurgia

Thesis Advisors: Vilella Cuadrada, Elisabet

Source: TDX (Tesis Doctorals en Xarxa)

Subject Terms: Genètica, Transcriptòmica, Trastorns psiquiàtrics, Trastornos psiquiátricos, Genetics, Transcriptomics, Psychiatric disorders, Ciències de la Salut

Time: 616.89

File Description: application/pdf

Access URL: http://hdl.handle.net/10803/690869

Modelling Parkinson in zebrafish: from understanding disease to discovering new therapies

Authors: García Fernández, Jéssica

Contributors: University/Department: Universitat Pompeu Fabra. Departament de Medicina i Ciències de la Vida

Thesis Advisors: Terriente, Javier, Santis, Flavia de

Source: TDX (Tesis Doctorals en Xarxa)

Subject Terms: Parkinson’s disease, zebrafish larvae, dopaminergic neurons, dysfunctional locomotion, CRISPR/Cas9, Sistema Inmune, disfunción mitocondrial, genes asociados a enfermedad de Párkinson, transcriptómica, patogénesis

Time: 616.8

File Description: application/pdf

Access URL: http://hdl.handle.net/10803/688560

Charting intra-tumoral heterogeneity dynamics through the integration of multi-modal single-cell profiles

Authors: Elosua-Bayés, Marc

Contributors: University/Department: Universitat Pompeu Fabra. Departament de Medicina i Ciències de la Vida

Thesis Advisors: Gut, Ivo Glynne, Heyn, Holger

Source: TDX (Tesis Doctorals en Xarxa)

Subject Terms: single-cell RNA-sequencing, seqüenciació d’ARN de cèl·lules individuals, Spatial Transcriptomics, Transcriptómica Espacial, Cell type deconvolution, Descomposició de tipus cel·lulars, Immuno-oncology, Immuno-oncologia, Tumor Immune Cell Atlas, Atlas de Cèl·lules Immunes, Schwann cells, Cèl·lules de Schwann, Cancer, Càncer, Metastasis, Metàstasi

File Description: application/pdf

Access URL: http://hdl.handle.net/10803/688558

Measuring the quantitative relationship between organismal gene expression and lifespan in Caenorhabditis elegans

Authors: Oswal, Natasha Nikhil

Contributors: University/Department: Universitat Pompeu Fabra. Departament de Medicina i Ciències de la Vida

Thesis Advisors: Stroustrup, Nicholas

Source: TDX (Tesis Doctorals en Xarxa)

Subject Terms: Longevidad, Envejecimiento, Transcriptómica, Nematódos, Insulina, Longevity, Ageing, Transcriptomics, Nematodes, Insulin

File Description: application/pdf

Access URL: http://hdl.handle.net/10803/688557

Evolution of tissue-specific transcriptomes across bilaterian animals

Authors: Mantica, Federica

Contributors: University/Department: Universitat Pompeu Fabra. Departament de Medicina i Ciències de la Vida

Thesis Advisors: Irimia Martínez, Manuel

Source: TDX (Tesis Doctorals en Xarxa)

Subject Terms: Transcriptomics, Evolution, Bilaterians, Gene expression, Alternative splicing, Transcriptómica, Evolución, Bilaterales, Expresion genica, Empalme alternativo

File Description: application/pdf

Access URL: http://hdl.handle.net/10803/688357

Shearing effects during pregnancy and productive and transcriptomic responses to heat stress according to phenotype (sensitive vs. tolerant) in dairy sheep

Authors: González Luna, Sandra

Thesis Advisors: Caja López, Gerardo, Salama, Ahmed A. K. (Ahmed Abdel-Rahman Kamal)

Source: TDX (Tesis Doctorals en Xarxa)

Subject Terms: Transcriptòmica, Transcriptómica, Transcriptomics, Ovella, Oveja, Sheep, Calor, Heat, Ciències Experimentals

File Description: application/pdf

Access URL: http://hdl.handle.net/10803/675279

Inter-individual variability and temporal scaling in the aging transcriptome

Authors: Martin, Olivier M. F.

Contributors: University/Department: Universitat Pompeu Fabra. Departament de Ciències Experimentals i de la Salut

Thesis Advisors: Stroustrup, Nicholas

Source: TDX (Tesis Doctorals en Xarxa)

Subject Terms: Envelliment, Variabilitat interindividual, Canvi d'escala temporal, Transcriptòmica, Caenorhabditis elegans, Aging Inter-individual variability, Temporal scaling, Transcriptomics

File Description: application/pdf

Access URL: http://hdl.handle.net/10803/674113

Unravelling the epigenomic, transcriptomic and cognitive interplay in Down syndrome

Authors: Sierra Noguera, Cèsar

Contributors: University/Department: Universitat Pompeu Fabra. Departament de Ciències Experimentals i de la Salut

Thesis Advisors: Dierssen, Mara

Source: TDX (Tesis Doctorals en Xarxa)

Subject Terms: Down syndrome, Neuroepigenetics, Single-cell, Transcriptomics, Chromatin, Síndrome de Down, Neuroepigenètica, Transcriptòmica, Cromatina

Time: 616.8

File Description: application/pdf

Access URL: http://hdl.handle.net/10803/673884

Targeting glial cells as a therapeutic approach for the treatment of chemotherapy-induced neuropathic pain

Authors: Piedra Barrull, Sheila

Contributors: University/Department: Universitat Pompeu Fabra. Departament de Ciències Experimentals i de la Salut

Thesis Advisors: Martín Sánchez, Miquel

Source: TDX (Tesis Doctorals en Xarxa)

Subject Terms: Neuropathic pain, Chemotherapy, Glial cells, Transcriptomics, Sigma-1 receptor, Dolor neuropático, Quimioterapia, Células gliales, Transcriptómica, Receptor Sigma-1

File Description: application/pdf

Access URL: http://hdl.handle.net/10803/673349

Análisis de la etiopatogenia del cadasil mediante estudios transcriptómicos y estimación del pronóstico tras el ictus isquémico en el cadasil

Authors: Muiño Acuña, Elena

Contributors: University/Department: Universitat Autònoma de Barcelona. Departament de Medicina

Thesis Advisors: Fernández Cadenas, Israel, Roquer González, Jaume, Montaner Villalonga, Joan

Source: TDX (Tesis Doctorals en Xarxa)

Subject Terms: Cadasil, Ictus, Stroke, Transcriptòmica, Transcriptómica, Transcriptomic, Ciències de la Salut

File Description: application/pdf

Access URL: http://hdl.handle.net/10803/670260