Gen-Doping: aktuelle Nachweisverfahren und analytische Herausforderungen

Gene doping: current test methods and analytical challenges

Συγγραφείς: Thevis, Mario^{Aff1, Aff2, IDs0010302604257z_cor1}, Thomas, Andreas^Aff1, Naumann, Nana^Aff1

Πηγή: Bundesgesundheitsblatt - Gesundheitsforschung - Gesundheitsschutz. 69(7):767-773

Protein Binding of Cefazolin is Not Saturated in Human Synovial Fluid After Single-Dose Perioperative Antibiotic Prophylaxis

Συγγραφείς: Ubl, Steffen T.^Aff1, Arnold, Luc M.^Aff1, Krombholz, Sophia^Aff2, Wafaisade, Arasch^Aff1, Guenther, Daniel^Aff1, Bouillon, Bertil^Aff1, Thevis, Mario^Aff2, Pfeiffer, Thomas R.^{Aff1, IDs1331802601009x_cor1}

Πηγή: European Journal of Drug Metabolism and Pharmacokinetics. :1-10

Prediction of human exposure and first-pass metabolism of the fungicide trifloxystrobin using an in vitro intestinal pancreatin and Caco-2/HT29-MTX model

Συγγραφείς: Hallscheidt, Eileen^{Aff1, Aff2}, Bothe, Kathrin^Aff3, Hahn, Maria^Aff2, Hartmann, Kerstin^Aff3, Thevis, Mario^Aff1, Lamshoeft, Marc^{Aff2, IDs0020402604340z_cor1}

Πηγή: Archives of Toxicology. 100(6):2381-2395

Doping

Συγγραφείς: Thevis, Mario^Aff412, Schänzer, Wilhelm^Aff412, Thomas, Andreas^Aff412, Walpurgis, Katja^Aff412

Συνεισφορές: Mooren, Frank C., editor^{Aff1, Aff2}, Schmitz, Boris, editor^{Aff3, Aff4}

Πηγή: Encyclopedia of Exercise Medicine in Health and Disease. :333-338

Detection of sample swapping in anti-doping investigations using machine learning

Συγγραφείς: Rahman, Maxx Richard, Piper, Thomas, Thevis, Mario, Maass, Wolfgang

Πηγή: Sci Rep

Θεματικοί όροι: Article

Σύνδεσμος πρόσβασης: https://pubmed.ncbi.nlm.nih.gov/41844716/
https://pmc.ncbi.nlm.nih.gov/articles/PMC13000201/
https://doi.org/10.1038/s41598-026-43502-y

Detection of sgRNA via SHERLOCK as Potential CRISPR Related Gene Doping Control Strategy

Συγγραφείς: Paßreiter, Alina^aff1, Naumann, Nana^aff1, Thomas, Andreas^aff1, Grogna, Nicolas^aff3, Delahaut, Philippe^aff3, Thevis, Mario^{aff1, aff2}

Πηγή: Analytical Chemistry. 96(19):7452-7459

Διαθεσιμότητα: https://pubs.acs.org/doi/10.1021/acs.analchem.3c05776

Establishing Personalized Blood Protein Reference Ranges Using Noninvasive Microsampling and Targeted Proteomics: Implications for Antidoping Strategies

Συγγραφείς: Richard, Vincent R.^aff1, Mitsa, Georgia^{aff1, aff2}, Eshghi, Azad^aff3, Chaplygina, Daria^aff1, Mohammed, Yassene^aff4, Goodlett, David R.^aff3, Zahedi, Rene P.^{aff5, aff6, aff7, aff8}, Thevis, Mario^{aff9, aff10}, Borchers, Christoph H.^{aff1, aff2, aff11, aff12}

Πηγή: Journal of Proteome Research. 23(5):1779-1787

Διαθεσιμότητα: https://pubs.acs.org/doi/10.1021/acs.jproteome.4c00020

Bioanalytical methods in doping controls: a review

Συγγραφείς: Thomas, Andreas, Walpurgis, Katja, Naumann, Nana, Piper, Thomas, Thevis, Mario

Πηγή: Bioanalysis

Θεματικοί όροι: Doping in Sports, Substance Abuse Detection, Anabolic Agents, Humans, Review, Performance-Enhancing Substances, Erythropoietin

Σύνδεσμος πρόσβασης: https://pubmed.ncbi.nlm.nih.gov/39916648
https://pubmed.ncbi.nlm.nih.gov/39916648/
https://doi.org/10.1080/17576180.2025.2460951
https://pmc.ncbi.nlm.nih.gov/articles/PMC11875490/

Physical exercise as a catalyst for neuroimmune balance in schizophrenia: Targeting the kynurenine pathway in the PsyLetics project

Συγγραφείς: Rißmayer, Matthias ^{a, b, c, ⁎}, Fischer, Julia ^{d, e, f, g}, Hanssen, Ruth ^{h, i}, Kretschmer, Alina Chloé ^{e, f, g, h}, Blaschke, Stefan J. ^a, Jelic, Sofija ^a, Annas, Sophia ^a, Rihm, Alina ^a, Markser, Anna ^f, Krombholz, Sophia ^j, Thevis, Mario ^j, Hohmann, Christopher ^k, Schönau, Eckhard ^c, Hokamp, Nils Große ^l, Bloch, Wilhelm ^m, Kambeitz, Joseph ^a, Javelle, Florian ^{b, 1}, Lichtenstein, Theresa ^{a, i, 1}

Πηγή: In Journal of Psychiatric Research July 2026 198:142-150

Gel Electrophoretic Detection of Black Market ACE‐031

Συγγραφείς: Reichel, Christian, Filip, Thomas, Gmeiner, Günter, Thevis, Mario

Πηγή: Drug Test Anal

Θεματικοί όροι: Activin Receptors, Type II, Recombinant Fusion Proteins, ACE-031, Blotting, Western, Performance-Enhancing Substances, Myostatin, Rats, Immunoglobulin Fc Fragments, Doping, Humans, Animals, Electrophoresis, Polyacrylamide Gel, Black Market, SDS-PAGE, Research Article

Περιγραφή αρχείου: application/pdf

Σύνδεσμος πρόσβασης: https://pubmed.ncbi.nlm.nih.gov/40312924
https://pubmed.ncbi.nlm.nih.gov/40312924/
https://pmc.ncbi.nlm.nih.gov/articles/PMC12489275/
https://doi.org/10.1002/dta.3898
https://phaidra.vetmeduni.ac.at/o:4995
https://doi.org/10.1002/dta.3898

A multivariate data analysis approach for the investigation of in vitro derived metabolites of ACP-105 in comparison with human in vivo metabolites

Συγγραφείς: Nilsson Broberg, Malin, Author, Tillgren Ohlsson, Rebecca, Author, Bondesson, Ulf, Author, Pettersson, Curt, Author, Tidstedt, Börje, Author, Thevis, Mario, Author, Hedeland, Mikael, Author

Συνεισφορές: Nilsson Broberg, Malin, Author, Tillgren Ohlsson, Rebecca, Author, Bondesson, Ulf, Author, Pettersson, Curt, Author, Tidstedt, Börje, Author, Thevis, Mario, Author, Hedeland, Mikael, Author

Πηγή: Journal of chromatography. B. 1231

Θεματικοί όροι: ACP-105, Doping control, MVDA, Metabolites in vivo and in vitro, Microsomes, UHPLC-HRMS

Περιγραφή αρχείου: electronic

Σύνδεσμος πρόσβασης: https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-517780
https://doi.org/10.1016/j.jchromb.2023.123927

Equine in vivo metabolite profiling of the selective androgen receptor modulator LGD-3303 for doping control

Συγγραφείς: Nilsson Broberg, Malin, Author, Knych, Heather, Author, Bondesson, Ulf, Author, Pettersson, Curt, Author, Tidstedt, Borje, Author, Stanley, Scott, Author, Thevis, Mario, Author, Hedeland, Mikael, Author

Συνεισφορές: Nilsson Broberg, Malin, Author, Knych, Heather, Author, Bondesson, Ulf, Author, Pettersson, Curt, Author, Tidstedt, Borje, Author, Stanley, Scott, Author, Thevis, Mario, Author, Hedeland, Mikael, Author

Πηγή: Journal of Pharmaceutical and Biomedical Analysis. 233

Θεματικοί όροι: Mass spectrometry, Selective androgen receptor modulator, LGD-3303, Doping control, Metabolites, Equine

Περιγραφή αρχείου: electronic

Σύνδεσμος πρόσβασης: https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-507451
https://doi.org/10.1016/j.jpba.2023.115468

Detection of the GH analogue somatrogon in doping control urine samples by means of LC-HRMS/MS

Συγγραφείς: Walpurgis, Katja^{Aff1, IDs41598025963614_cor1}, Thomas, Andreas^Aff1, Rauer, Alexandra^Aff1, Majer, Bettina^Aff1, Sato, Mitsuhiko^Aff2, Okano, Masato^Aff2, Al-Jaber, Maneera^Aff3, Abushareeda, Wadha^Aff3, Arsene, Cristian-Gabriel^Aff4, Geyer, Hans^{Aff1, Aff5}, Thevis, Mario^{Aff1, Aff5}

Πηγή: Scientific Reports. 15(1)

Combined detection of inhibitors of the activin receptor signaling pathways (IASPs) by means of LC-HRMS/MS for human doping control

Συγγραφείς: Sakellariou, Panagiotis^{Aff1, IDs4159802503562y_cor1}, Walpurgis, Katja^{Aff1, IDs4159802503562y_cor2}, Thomas, Andreas^Aff1, Marchand, Alexandre^Aff2, Miller, Geoff^Aff3, Dellanna, Frank^Aff4, Thevis, Mario^{Aff4, Aff5}

Πηγή: Scientific Reports. 15(1)

Multiplex detection of seven transgenes for human gene doping analysis

Συγγραφείς: Naumann, Nana^{Aff1, IDs41598025066774_cor1}, Do, Carolin^Aff1, Vollmert, Caren^Aff3, Krajina, Maroje^Aff3, Thomas, Andreas^Aff1, Cheung, Hiu Wing^Aff4, Wong, Kin-Sing^Aff4, Wan, Terence S. M.^Aff4, Ho, Emmie N. M.^Aff4, Thevis, Mario^{Aff1, Aff2, IDs41598025066774_cor2}

Πηγή: Scientific Reports. 15(1)

Device does matter! Comparison of PEth 16:0/18:1 and PEth 16:0/18:2 blood concentrations determined from three dried blood spot sampling devices

Συγγραφείς: Hose, Jeremai ^{a, ⁎, 1}, Stach, Paul ^a, Reda, Sara ^b, Juebner, Martin ^a, Thevis, Mario ^c, Andresen-Streichert, Hilke ^a

Πηγή: In Journal of Pharmaceutical and Biomedical Analysis 15 April 2026 271

The mystery of post-mortem Gamma-hydroxybutyrate formation - method development and validation for the detection of endogenous GHB and its related compounds

Συγγραφείς: Kietzerow, Jana ^{a, ⁎}, Thevis, Mario ^b, Andresen-Streichert, Hilke ^a

Πηγή: In Forensic Science International April 2026 381

A multivariate Bayesian learning approach for improved detection of doping in athletes using urinary steroid profiles

Συγγραφείς: Eleftheriou, Dimitra, Piper, Thomas, Thevis, Mario, Neocleous, Tereza

Θεματικοί όροι: Statistics - Applications

Σύνδεσμος πρόσβασης: http://arxiv.org/abs/2310.13980

Integrating static and dynamic human in vitro gut-models to assess intestinal absorption, metabolism, and non-specific binding of pesticides

Συγγραφείς: Hallscheidt, Eileen ^{a, b}, Assbrock, Leonie ^b, Hahn, Maria ^b, Kuehnlenz, Julia ^c, Thevis, Mario ^a, Lamshoeft, Marc ^{b, ⁎}

Πηγή: In NAM Journal 2026 2

From in vitro permeability to in vivo brain exposure: continued validation of a human iPSC-derived blood-brain barrier model with pesticides and stimulants

Συγγραφείς: Kurtenbach, Paul ^{a, b}, Hahn, Maria ^a, Thevis, Mario ^{b, c, ⁎}, Lamshöft, Marc ^a

Πηγή: In NAM Journal 2026 2