Clinical Meaningfulness of the Composite Endpoint, COPDCompEx, in Defining Exacerbations and Worsening of COPD: A Post Hoc Analysis of 4 Clinical Interventional Studies of COPD

Συγγραφείς: Tal-Singer R, Vogelmeier CF, Bolton C, Bengtsson T, Peterson S, Sidaway M, Da Silva CA

Πηγή: International Journal of COPD, Vol 21, Iss Issue 1, Pp 1-13 (2026)

Θεματικοί όροι: Acute worsening event, Composite endpoint, Patient-centric, Pulmonary disease tool, Diseases of the respiratory system, RC705-779

Περιγραφή αρχείου: electronic resource

Relation: https://www.dovepress.com/clinical-meaningfulness-of-the-composite-endpoint-copdcompex-in-defini-peer-reviewed-fulltext-article-COPD; https://doaj.org/toc/1178-2005

Σύνδεσμος πρόσβασης: https://doaj.org/article/ddce793be3ed4b428bfd4cf65245b883

Treatment decisions: insights from people with asthma or COPD and their healthcare providers on disease and treatment decisions

Συγγραφείς: Tal-Singer R, Román-Rodríguez M, McMullan I, Warner M, Compton C, Orlow JM, Han MK

Πηγή: Patient Preference and Adherence, Vol 19, Iss Issue 1, Pp 1583-1591 (2025)

Θεματικοί όροι: COPD, Asthma, Patient insights, Inhalers, Disease management, Treatment decisions, Medicine (General), R5-920

Περιγραφή αρχείου: electronic resource

Relation: https://www.dovepress.com/treatment-decisions-insights-from-people-with-asthma-or-copd-and-their-peer-reviewed-fulltext-article-PPA; https://doaj.org/toc/1177-889X

Σύνδεσμος πρόσβασης: https://doaj.org/article/ad7f1a5481a44080a6e4e09d46b6c4e1

Disease Impact and Perception of Biologics in Adults with Type 2 Inflammation Respiratory Disease: International Survey Results

Συγγραφείς: Tal-Singer R, Willard KS, Luttmann MA, Sprankle M, Reynolds J, Muerza Santos I, Jaffee H, Vichiendilokkul A, Jacomelli C, Novak Š, Gascon Moreno V, Wise RA

Πηγή: Patient Preference and Adherence, Vol 19, Pp 1159-1170 (2025)

Θεματικοί όροι: asthma, chronic rhinosinusitis with nasal polyps, injection, burden, Medicine (General), R5-920

Περιγραφή αρχείου: electronic resource

Relation: https://www.dovepress.com/disease-impact-and-perception-of-biologics-in-adults-with-type-2-infla-peer-reviewed-fulltext-article-PPA; https://doaj.org/toc/1177-889X

Σύνδεσμος πρόσβασης: https://doaj.org/article/e4a70f8ce5f0496a9441fee7c3f23b85

Perspectives on Treatment Decisions, Preferences, and Adherence and Long-Term Management in Asthma and COPD: A Qualitative Analysis of Patient, Caregiver, and Healthcare Provider Insights

Συγγραφείς: Román-Rodríguez M, McMullan I, Warner M, Compton CH, Tal-Singer R, Orlow JM, Han MK

Πηγή: Patient Preference and Adherence, Vol 18, Pp 2295-2306 (2024)

Θεματικοί όροι: single inhaler triple therapy, multiple inhaler triple therapy, treatment goals, medical advice, patient education, quality of life, Medicine (General), R5-920

Περιγραφή αρχείου: electronic resource

Relation: https://www.dovepress.com/perspectives-on-treatment-decisions-preferences-and-adherence-and-long-peer-reviewed-fulltext-article-PPA; https://doaj.org/toc/1177-889X

Σύνδεσμος πρόσβασης: https://doaj.org/article/492b448175c7416eac0f701163da95fe

A Telemedicine Approach for Monitoring COPD: A Prospective Feasibility and Acceptability Cohort Study

Συγγραφείς: Shinoda M, Hataji O, Miura M, Kinoshita M, Mizoo A, Tobino K, Soutome T, Nishi T, Ishii T, Miller BE, Tal-Singer R, Tomlinson R, Matsuki T, Jones PW, Shibata Y

Πηγή: International Journal of COPD, Vol 17, Pp 2931-2944 (2022)

Θεματικοί όροι: japan, patient-reported outcome measure, feasibility, acceptability, telemonitoring, smartphone, Diseases of the respiratory system, RC705-779

Περιγραφή αρχείου: electronic resource

Relation: https://www.dovepress.com/a-telemedicine-approach-for-monitoring-copd-a-prospective-feasibility--peer-reviewed-fulltext-article-COPD; https://doaj.org/toc/1178-2005

Σύνδεσμος πρόσβασης: https://doaj.org/article/8674ae5031d7489eba575c19576519c6

Prevalence and Characteristics of Individuals with Preserved Ratio Impaired Spirometry (PRISm) and/or Impaired Lung Function in Japan: The OCEAN Study

Συγγραφείς: Kaise T, Sakihara E, Tamaki K, Miyata H, Hirahara N, Kirichek O, Tawara R, Akiyama S, Katsumata M, Haruya M, Ishii T, Simard EP, Miller BE, Tal-Singer R

Πηγή: International Journal of COPD, Vol 16, Pp 2665-2675 (2021)

Θεματικοί όροι: capture, caat, prism, copd-q, japan, airflow limitation, Diseases of the respiratory system, RC705-779

Περιγραφή αρχείου: electronic resource

Relation: https://www.dovepress.com/prevalence-and-characteristics-of-individuals-with-preserved-ratio-imp-peer-reviewed-fulltext-article-COPD; https://doaj.org/toc/1178-2005

Σύνδεσμος πρόσβασης: https://doaj.org/article/500e71a56e3e44c7abae2c50682f20b2

Co-Morbidity Patterns Identified Using Latent Class Analysis of Medications Predict All-Cause Mortality Independent of Other Known Risk Factors: The COPDGene® Study

Συγγραφείς: Li Y, Ragland M, Austin E, Young K, Pratte K, Hokanson JE, Beaty TH, Regan EA, Rennard SI, Wern C, Jacobs MR, Tal-Singer R, Make BJ, Kinney GL

Πηγή: Clinical Epidemiology, Vol 12, Pp 1171-1181 (2020)

Θεματικοί όροι: copdgene, co-morbidities, latent class analysis, medication patterns, mortality, Infectious and parasitic diseases, RC109-216

Περιγραφή αρχείου: electronic resource

Relation: https://www.dovepress.com/co-morbidity-patterns-identified-using-latent-class-analysis-of-medica-peer-reviewed-article-CLEP; https://doaj.org/toc/1179-1349

Σύνδεσμος πρόσβασης: https://doaj.org/article/c54e625dac5c4edfa09d0f20f9c392f5

Defining Chronic Mucus Hypersecretion Using the CAT in the SPIROMICS Cohort

Συγγραφείς: Stott-Miller M, Müllerová H, Miller B, Tabberer M, El Baou C, Keeley T, Martinez FJ, Han M, Dransfield M, Hansel NN, Cooper CB, Woodruff P, Ortega VE, Comellas AP, Paine R III, Kanner RE, Anderson W, Drummond MB, Kim V, Tal-Singer R, Lazaar AL

Πηγή: International Journal of COPD, Vol 15, Pp 2467-2476 (2020)

Θεματικοί όροι: copd, sgrq, exacerbation, cat, cough, phlegm, Diseases of the respiratory system, RC705-779

Περιγραφή αρχείου: electronic resource

Relation: https://www.dovepress.com/defining-chronic-mucus-hypersecretion-using-the-cat-in-the-spiromics-c-peer-reviewed-article-COPD; https://doaj.org/toc/1178-2005

Σύνδεσμος πρόσβασης: https://doaj.org/article/8ccad5b4101240ca8246e14891a11fef

Increased von Willebrand Factor Processing in COPD, Reflecting Lung Epithelium Damage, Is Associated with Emphysema, Exacerbations and Elevated Mortality Risk

Συγγραφείς: Langholm LL, Rønnow SR, Sand JMB, Leeming DJ, Tal-Singer R, Miller BE, Vestbo J, Karsdal MA, Manon-Jensen T

Πηγή: International Journal of COPD, Vol 15, Pp 543-552 (2020)

Θεματικοί όροι: von willebrand factor processing, copd, emphysema, exacerbations, increased mortality risk., Diseases of the respiratory system, RC705-779

Περιγραφή αρχείου: electronic resource

Relation: https://www.dovepress.com/increased-von-willebrand-factor-processing-in-copd-reflecting-lung-epi-peer-reviewed-article-COPD; https://doaj.org/toc/1178-2005

Σύνδεσμος πρόσβασης: https://doaj.org/article/bfcf5a5c9a944f0c9ade608666817afa

Fibrinogen, chronic obstructive pulmonary disease (COPD) and outcomes in two United States cohorts

Συγγραφείς: Mannino DM, Müellerova H, Valvi D, Tal-Singer R

Πηγή: International Journal of COPD, Vol 2012, Iss default, Pp 173-182 (2012)

Θεματικοί όροι: Diseases of the respiratory system, RC705-779

Περιγραφή αρχείου: electronic resource

Relation: http://www.dovepress.com/fibrinogen-chronic-obstructive-pulmonary-disease-copd-and-outcomes-in--a9432; https://doaj.org/toc/1176-9106; https://doaj.org/toc/1178-2005

Σύνδεσμος πρόσβασης: https://doaj.org/article/a8e5b433d4814b6fb4d45b797997d587

Genetic diversity fuels gene discovery for tobacco and alcohol use

Συγγραφείς: Saunders GRB, Wang X, Chen F, Jang SK, Liu M, Wang C, Gao S, Jiang Y, Khunsriraksakul C, Otto JM, Addison C, Akiyama M, Albert CM, Aliev F, Alonso A, Arnett DK, Ashley-Koch AE, Ashrani AA, Barnes KC, Barr RG, Bartz TM, Becker DM, Bielak LF, Benjamin EJ, Bis JC, Bjornsdottir G, Blangero J, Bleecker ER, Boardman JD, Boerwinkle E, Boomsma DI, Boorgula MP, Bowden DW, Brody JA, Cade BE, Chasman DI, Chavan S, Chen YI, Chen Z, Cheng I, Cho MH, Choquet H, Cole JW, Cornelis MC, Cucca F, Curran JE, de Andrade M, Dick DM, Docherty AR, Duggirala R, Eaton CB, Ehringer MA, Esko T, Faul JD, Fernandes Silva L, Fiorillo E, Fornage M, Freedman BI, Gabrielsen ME, Garrett ME, Gharib SA, Gieger C, Gillespie N, Glahn DC, Gordon SD, Gu CC, Gu D, Gudbjartsson DF, Guo X, Haessler J, Hall ME, Haller T, Harris KM, He J, Herd P, Hewitt JK, Hickie I, Hidalgo B, Hokanson JE, Hopfer C, Hottenga J, Hou L, Huang H, Hung YJ, Hunter DJ, Hveem K, Hwang SJ, Hwu CM, Iacono W, Irvin MR, Jee YH, Johnson EO, Joo YY, Jorgenson E, Justice AE, Kamatani Y, Kaplan RC, Kaprio J, Kardia SLR, Keller MC, Kelly TN, Kooperberg C, Korhonen T, Kraft P, Krauter K, Kuusisto J, Laakso M, Lasky-Su J, Lee WJ, Lee JJ, Levy D, Li L, Li K, Li Y, Lin K, Lind PA, Liu C, Lloyd-Jones DM, Lutz SM, Ma J, Mägi R, Manichaikul A, Martin NG, Mathur R, Matoba N, McArdle PF, McGue M, McQueen MB, Medland SE, Metspalu A, Meyers DA, Millwood IY, Mitchell BD, Mohlke KL, Moll M, Montasser ME, Morrison AC, Mulas A, Nielsen JB, North KE, Oelsner EC, Okada Y, Orrù V, Palmer ND, Palviainen T, Pandit A, Park SL, Peters U, Peters A, Peyser PA, Polderman TJC, Rafaels N, Redline S, Reed RM, Reiner AP, Rice JP, Rich SS, Richmond NE, Roan C, Rotter JI, Rueschman MN, Runarsdottir V, Saccone NL, Schwartz DA, Shadyab AH, Shi J, Shringarpure SS, Sicinski K, Skogholt AH, Smith JA, Smith NL, Sotoodehnia N, Stallings MC, Stefansson H, Stefansson K, Stitzel JA, Sun X, Syed M, Tal-Singer R, Taylor AE, Taylor KD, Telen MJ, Thai KK, Tiwari H, Turman C, Tyrfingsson T, Wall TL, Walters RG, Weir DR, Weiss ST, White WB, Whitfield JB, Wiggins KL, Willemsen G, Willer CJ, Winsvold BS, Xu H, Yanek LR, Yin J, Young KL, Young KA, Yu B, Zhao W, Zhou W, Zöllner S, Zuccolo L, 23andMe Research Team, Biobank Japan Project, Batini C, Bergen AW, Bierut LJ, David SP, Gagliano Taliun SA, Hancock DB, Jiang B, Munafò MR, Thorgeirsson TE, Liu DJ, Vrieze S.

Συνεισφορές: Institute for Molecular Medicine Finland, University Management, Tellervo Korhonen / Principal Investigator, Genetic Epidemiology, University of Helsinki

Πηγή: Nature
23andMe Research team & The Biobank Japan Project 2022, 'Genetic diversity fuels gene discovery for tobacco and alcohol use', Nature, vol. 612, no. 7941, pp. 720-724. https://doi.org/10.1038/s41586-022-05477-4
the 23 and Me Research Team 2022, 'Genetic diversity fuels gene discovery for tobacco and alcohol use', Nature, vol. 612, no. 7941, pp. 720-724. https://doi.org/10.1038/s41586-022-05477-4
Nature, vol 612, iss 7941

Θεματικοί όροι: 0301 basic medicine, Multifactorial Inheritance, Internationality, tobacco, Alcohol Use and Health, Substance Misuse, Tobacco Use, Risk Factors, Biobank Japan Project, Medicine and Health Sciences, 2.1 Biological and endogenous factors, Disease, Aetiology, name=TARG, Cancer, Psychiatry, 0303 health sciences, alcohol, Genetic Predisposition to Disease/genetics, Neurotrophic factors, Single Nucleotide, 3. Good health, Europe, Alcoholism, Genetic Variation/genetics, Genetics, developmental biology, physiology, Genetic Loci/genetics, Genome-Wide Association Study/methods, Alcohol Drinking, General Science & Technology, 23andMe Research Team, Europe/ethnology, Article, 03 medical and health sciences, SDG 3 - Good Health and Well-being, Tobacco, Genetics, Humans, Genetic Predisposition to Disease, Polymorphism, Multifactorial Inheritance/genetics, Prevention, Protein, Human Genome, Genetic Variation, Alcohol Drinking/genetics, Biomedicine, Good Health and Well Being, Tobacco Use/genetics, Genetic Loci, Sample Size, Prediction, Transcriptome, Model, Genome-Wide Association Study

Περιγραφή αρχείου: application/pdf

Σύνδεσμος πρόσβασης: https://pubmed.ncbi.nlm.nih.gov/36477530
https://www.scopus.com/pages/publications/85143637078
https://doi.org/10.1038/s41586-022-05477-4
https://research.vumc.nl/en/publications/a453efbe-340a-43a3-bca0-133b89797e8e
https://pure.amsterdamumc.nl/en/publications/2e4793df-8035-4011-9603-3fcf0b6a6bb1
https://doi.org/10.1038/s41586-022-05477-4
http://hdl.handle.net/10138/356325
https://epub.ub.uni-muenchen.de/93923/
https://escholarship.org/content/qt6fz7j79q/qt6fz7j79q.pdf
https://escholarship.org/uc/item/6fz7j79q

Polygenic and transcriptional risk scores identify chronic obstructive pulmonary disease subtypes in the COPDGene and ECLIPSE cohort studies

Συγγραφείς: Moll, M, Hecker, J, Platig, J, Zhang, J, Ghosh, AJ, Pratte, KA, Wang, RS, Hill, D, Konigsberg, IR, Chiles, JW, Hersh, CP, Castaldi, PJ, Glass, K, Dy, JG, Sin, DD, Tal-Singer, R, Mouded, M, Rennard, SI, Anderson, GP, Kinney, GL, Bowler, RP, Curtis, JL, McDonald, ML, Silverman, EK, Hobbs, BD, Cho, MH

Relation: https://hdl.handle.net/11343/359143

Διαθεσιμότητα: https://hdl.handle.net/11343/359143

Evaluation of intranasal TLR2/6 agonist INNA-051: safety, tolerability and proof of pharmacology.

Συγγραφείς: Mercuri, FA, White, S, McQuilten, HA, Lemech, C, Mynhardt, S, Hari, R, Zhang, P, Kruger, N, McLachlan, G, Miller, BE, West, NP, Tal-Singer, R, Demaison, C

Relation: https://hdl.handle.net/11343/352791

Διαθεσιμότητα: https://hdl.handle.net/11343/352791

M9 Importance of patient voice in guiding the management of COPD

Συγγραφείς: Han, MK, McMullan, I, Warner, M, Compton, C, Sharma, R, Tal-Singer, R, Román-Rodríguez, M

Πηγή: ‘The long and winding road’ – Optimising patient experience of respiratory care ; page A264.1-A264

Διαθεσιμότητα: https://doi.org/10.1136/thorax-2023-btsabstracts.398
https://syndication.highwire.org/content/doi/10.1136/thorax-2023-BTSabstracts.398

A32-42 Patient Insights on Experience With Metered-dose Inhalers Using Novel Low-carbon Propellant HFA-152a Compared With the Current Propellant HFA-134a

Συγγραφείς: Tal-Singer, R, Han, M K, Kaplan, A, Van, J, Palen, Der, Zavod, M, Parry, J, Donald, A, Slade, D, Papi, E, Plank, M

Πηγή: American Journal of Respiratory and Critical Care Medicine ; volume 212, issue Supplement_2 ; ISSN 1073-449X 1535-4970

Διαθεσιμότητα: https://doi.org/10.1093/ajrccm/aamag286.040
https://academic.oup.com/ajrccm/article-pdf/212/Supplement_2/aamag286.040/68565513/aamag286.040.pdf

B15-03 Astegolimab Decreases Exacerbation Risk in Patients With COPD With Frequent Exacerbations, Irrespective of Blood Eosinophil Count: Pooled Analysis of the Pivotal Randomized Trials ALIENTO and ARNASA

Συγγραφείς: Wedzicha, J A, Agusti, A, Brightling, C E, Calverley, P, Chalmers, J D, Greening, N, Han, M K, Mohan, D, Ng, J, Papi, A, Roche, N, Saenz, R, Samara, K, Tal-Singer, R, Vogelmeier, C F, Yang, X, Celli, B

Πηγή: American Journal of Respiratory and Critical Care Medicine ; volume 212, issue Supplement_1 ; ISSN 1073-449X 1535-4970

Διαθεσιμότητα: https://doi.org/10.1093/ajrccm/aamag162.1748
https://academic.oup.com/ajrccm/article-pdf/212/Supplement_1/aamag162.1748/68305793/aamag162.1748.pdf

C37-05 Attitudes Toward Vaccines and Antivirals for Viral Respiratory Infections in a Survey of U.S. Adults With Chronic Lung Conditions

Συγγραφείς: Tal-Singer, R, McCreary, G, Luttmann, M A, Williams, S, Willard, K, Wise, R, Ortiz, J R

Πηγή: American Journal of Respiratory and Critical Care Medicine ; volume 212, issue Supplement_1 ; ISSN 1073-449X 1535-4970

Διαθεσιμότητα: https://doi.org/10.1093/ajrccm/aamag162.4433
https://academic.oup.com/ajrccm/article-pdf/212/Supplement_1/aamag162.4433/68314347/aamag162.4433.pdf

C37-06 Vaccines Perceptions, Capacities, and Barriers Faced in Latin American Communities: A Study From Patient Organizations and Social Community Leaders

Συγγραφείς: Tal-Singer, R, Borges, F, Burgos, F, Denis, M M, Grajales, D, Gascon, V

Πηγή: American Journal of Respiratory and Critical Care Medicine ; volume 212, issue Supplement_1 ; ISSN 1073-449X 1535-4970

Διαθεσιμότητα: https://doi.org/10.1093/ajrccm/aamag162.1037
https://academic.oup.com/ajrccm/article-pdf/212/Supplement_1/aamag162.1037/68304351/aamag162.1037.pdf

C35-27 Initial Patient Impressions Reflect Improved Well-Being, Activity, and Independence Following Treatment With Ohtuvayre: A Global Allergy and Airways Patient Platform (GAAPP) Focus Group

Συγγραφείς: Tal-Singer, R, McCreaery, G, Williams, S, Butt, M Y, Kable, S, Wise, R

Πηγή: American Journal of Respiratory and Critical Care Medicine ; volume 212, issue Supplement_1 ; ISSN 1073-449X 1535-4970

Διαθεσιμότητα: https://doi.org/10.1093/ajrccm/aamag162.1969
https://academic.oup.com/ajrccm/article-pdf/212/Supplement_1/aamag162.1969/68305122/aamag162.1969.pdf

A36-22 A Patient Charter for People Living With Chronic Rhinosinusitis With Nasal Polyps: Multinational Perspectives From the Gaapp Community Survey

Συγγραφείς: Tal-Singer, R, Bertels, X, Willard, K, Gascon, V

Πηγή: American Journal of Respiratory and Critical Care Medicine ; volume 212, issue Supplement_1 ; ISSN 1073-449X 1535-4970

Διαθεσιμότητα: https://doi.org/10.1093/ajrccm/aamag162.903
https://academic.oup.com/ajrccm/article-pdf/212/Supplement_1/aamag162.903/68304390/aamag162.903.pdf