Vitamin D receptor/sirtuin 3 pathway mediates the cardioprotective effects of aerobic exercise in diabetic mice.

Συγγραφείς: Cui XN; School of Exercise and Health, Shanghai University of Sport, Shanghai, China., Li C; School of Exercise and Health, Shanghai University of Sport, Shanghai, China., Qin YH; School of Exercise and Health, Shanghai University of Sport, Shanghai, China., Liu JJ; School of Exercise and Health, Shanghai University of Sport, Shanghai, China., Jia CK; School of Exercise and Health, Shanghai University of Sport, Shanghai, China., Sun XY; School of Exercise and Health, Shanghai University of Sport, Shanghai, China., Lu SQ; School of Exercise and Health, Shanghai University of Sport, Shanghai, China., Zhu Z; School of Exercise and Health, Shanghai University of Sport, Shanghai, China., Cao ZB; School of Exercise and Health, Shanghai University of Sport, Shanghai, China; Key Laboratory of Exercise and Health Sciences of Ministry of Education, Shanghai University of Sport, Shanghai, China. Electronic address: caozb_edu@yahoo.co.jp.

Πηγή: Free radical biology & medicine [Free Radic Biol Med] 2026 Aug 16; Vol. 252, pp. 664-676. Date of Electronic Publication: 2026 Apr 28.

Τύπος έκδοσης: Journal Article

Στοιχεία περιοδικού: Publisher: Elsevier Science Country of Publication: United States NLM ID: 8709159 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-4596 (Electronic) Linking ISSN: 08915849 NLM ISO Abbreviation: Free Radic Biol Med Subsets: MEDLINE

Ιατρικοί όροι (MeSH): Receptors, Calcitriol*/metabolism , Receptors, Calcitriol*/genetics , Diabetic Cardiomyopathies*/metabolism , Diabetic Cardiomyopathies*/pathology , Diabetic Cardiomyopathies*/etiology , Diabetic Cardiomyopathies*/prevention & control , Diabetic Cardiomyopathies*/therapy , Diabetic Cardiomyopathies*/genetics , Sirtuin 3*/metabolism , Sirtuin 3*/genetics , Diabetes Mellitus, Experimental*/metabolism , Diabetes Mellitus, Experimental*/pathology , Diabetes Mellitus, Experimental*/therapy , Physical Conditioning, Animal*, Myocytes, Cardiac/metabolism ; Myocytes, Cardiac/pathology ; Cholecalciferol/pharmacology ; Animals ; Mice ; Male ; Mice, Inbred C57BL ; Signal Transduction ; Cell Line

Melatonin alleviates mitochondrial damage by regulating SIRT3‑mediated mitochondrial dynamics in granulosa cells under PCOS‑like conditions.

Συγγραφείς: Xie C; Hebei Key Laboratory of Reproductive Medicine, Hebei Reproductive Health Hospital, Shijiazhuang, Hebei 050071, P.R. China., Liu Z; Institute of Paediatrics, Hebei Provincial Clinical Research Centre for Child Health and Disease, Hebei Children's Hospital, Shijiazhuang, Hebei 050031, P.R. China., Chen T; Department of Biochemistry and Molecule Biology, Hebei Medical University, Shijiazhuang, Hebei 050017, P.R. China., Lu H; Hebei Key Laboratory of Reproductive Medicine, Hebei Reproductive Health Hospital, Shijiazhuang, Hebei 050071, P.R. China., Zhang X; Hebei Key Laboratory of Reproductive Medicine, Hebei Reproductive Health Hospital, Shijiazhuang, Hebei 050071, P.R. China., Yu W; Hebei Key Laboratory of Reproductive Medicine, Hebei Reproductive Health Hospital, Shijiazhuang, Hebei 050071, P.R. China., Zhang J; Hebei Key Laboratory of Reproductive Medicine, Hebei Reproductive Health Hospital, Shijiazhuang, Hebei 050071, P.R. China., Shang D; Department of Biochemistry and Molecule Biology, Hebei Medical University, Shijiazhuang, Hebei 050017, P.R. China., Wang X; Hebei Key Laboratory of Reproductive Medicine, Hebei Reproductive Health Hospital, Shijiazhuang, Hebei 050071, P.R. China.

Πηγή: Molecular medicine reports [Mol Med Rep] 2026 Aug; Vol. 34 (2). Date of Electronic Publication: 2026 Jun 11.

Τύπος έκδοσης: Journal Article

Στοιχεία περιοδικού: Publisher: D. A. Spandidos Country of Publication: Greece NLM ID: 101475259 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1791-3004 (Electronic) Linking ISSN: 17912997 NLM ISO Abbreviation: Mol Med Rep Subsets: MEDLINE

Ιατρικοί όροι (MeSH): Sirtuin 3*/metabolism , Sirtuin 3*/genetics , Melatonin*/pharmacology , Polycystic Ovary Syndrome*/metabolism , Polycystic Ovary Syndrome*/pathology , Polycystic Ovary Syndrome*/drug therapy , Granulosa Cells*/metabolism , Granulosa Cells*/drug effects , Granulosa Cells*/pathology , Mitochondrial Dynamics*/drug effects , Mitochondria*/metabolism , Mitochondria*/drug effects , Mitochondria*/pathology, Mitophagy/drug effects ; Membrane Potential, Mitochondrial/drug effects ; Dihydrotestosterone/pharmacology ; Autophagy/drug effects ; Female ; Humans ; Cell Line

Loss of sirtuin 3 disrupts cellular senescence signaling pathways.

Συγγραφείς: Kura N; Jean Mayer USDA Human Nutrition Research On Aging at Tufts University, Boston, MA, 02111, USA.; Graduate School of Biological Sciences, Tufts University, Boston, MA, 02111, USA., Mogck BA; Jean Mayer USDA Human Nutrition Research On Aging at Tufts University, Boston, MA, 02111, USA., Jezak ST; Jean Mayer USDA Human Nutrition Research On Aging at Tufts University, Boston, MA, 02111, USA.; Friedman School of Nutrition Science & Policy, Tufts University, Boston, MA, 02111, USA., Velarde MC; Institute of Biology, College of Science, University of the Philippines, 1101, Quezon City, Philippines., Wiley CD; Jean Mayer USDA Human Nutrition Research On Aging at Tufts University, Boston, MA, 02111, USA. christopher.wiley@tufts.edu.; Graduate School of Biological Sciences, Tufts University, Boston, MA, 02111, USA. christopher.wiley@tufts.edu.; Friedman School of Nutrition Science & Policy, Tufts University, Boston, MA, 02111, USA. christopher.wiley@tufts.edu.; Department of Medicine, School of Medicine, Tufts University, Boston, MA, 02111, USA. christopher.wiley@tufts.edu.

Πηγή: GeroScience [Geroscience] 2026 Jun; Vol. 48 (3), pp. 3483-3495. Date of Electronic Publication: 2026 May 06.

Τύπος έκδοσης: Journal Article

Στοιχεία περιοδικού: Publisher: Springer International Publishing Country of Publication: Switzerland NLM ID: 101686284 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2509-2723 (Electronic) Linking ISSN: 25092723 NLM ISO Abbreviation: Geroscience Subsets: MEDLINE

Ιατρικοί όροι (MeSH): Sirtuin 3*/genetics , Sirtuin 3*/deficiency , Sirtuin 3*/metabolism , Cellular Senescence*/physiology , Cellular Senescence*/genetics , Signal Transduction* , Senescence-Associated Secretory Phenotype*, Fibroblasts/metabolism ; Wound Healing/physiology ; Tumor Suppressor Protein p53/metabolism ; Animals ; Mice, Knockout ; Mice ; Aging

SIRT3-mediated deacetylation of ATP5A1 improves mitochondrial function to attenuate myocardial ischemia-reperfusion injury.

Συγγραφείς: Chen Y; Institute of Basic Medicine, Xiyuan Hospital, China Academy of Chinese Medical Sciences, Beijing, 100091, China., Xin G; School of Pharmaceutical Sciences, Zhejiang Chinese Medical University, Hangzhou, 310053, China., Zhang H; Institute of Basic Medicine, Xiyuan Hospital, China Academy of Chinese Medical Sciences, Beijing, 100091, China., Cui X; Institute of Basic Medicine, Xiyuan Hospital, China Academy of Chinese Medical Sciences, Beijing, 100091, China., Gao J; Institute of Basic Medicine, Xiyuan Hospital, China Academy of Chinese Medical Sciences, Beijing, 100091, China., Liu Z; Institute of Basic Medicine, Xiyuan Hospital, China Academy of Chinese Medical Sciences, Beijing, 100091, China., Guo F; Institute of Basic Medicine, Xiyuan Hospital, China Academy of Chinese Medical Sciences, Beijing, 100091, China., Guo H; Safety Laboratory, Xiyuan Hospital, China Academy of Chinese Medical Sciences, Beijing, 100091, China. Electronic address: g0502g@163.com., Fu J; Institute of Basic Medicine, Xiyuan Hospital, China Academy of Chinese Medical Sciences, Beijing, 100091, China. Electronic address: jianhuaffcn@263.net.

Πηγή: Biochemical and biophysical research communications [Biochem Biophys Res Commun] 2026 Aug 06; Vol. 825, pp. 153990. Date of Electronic Publication: 2026 May 19.

Τύπος έκδοσης: Journal Article; Research Support, Non-U.S. Gov't

Στοιχεία περιοδικού: Publisher: Elsevier Country of Publication: United States NLM ID: 0372516 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1090-2104 (Electronic) Linking ISSN: 0006291X NLM ISO Abbreviation: Biochem Biophys Res Commun Subsets: MEDLINE

Ιατρικοί όροι (MeSH): Sirtuin 3*/metabolism , Sirtuin 3*/genetics , Myocardial Reperfusion Injury*/metabolism , Myocardial Reperfusion Injury*/pathology , Myocardial Reperfusion Injury*/genetics , Mitochondrial Proton-Translocating ATPases*/metabolism , Mitochondria, Heart*/metabolism , Mitochondria*/metabolism, Myocytes, Cardiac/metabolism ; Myocytes, Cardiac/pathology ; Animals ; Acetylation ; Mice ; Apoptosis ; Mice, Inbred C57BL ; Male ; Cell Line

miR-145-5p Targets KLF4 to Regulate the SIRT3/GPX4 Axis, Mediating Ferroptosis and Exacerbating Tubular Epithelial Cell Injury in Diabetic Nephropathy.

Συγγραφείς: Tan H; Xianning Central Hospital (The First Affiliated Hospital of Hubei University of Science and Technology), Xianning, Hubei, China., Lu Z; People's Hospital of Tongcheng County, Xianning, Hubei, China., Xu M; The Second Affiliated Hospital of Hubei University of Science and Technology, Xianning, Hubei, China., Wu G; School of Clinical Medicine, Xianning Medical College, Hubei University of Science and Technology, Xianning, Hubei, China.; National Demonstration Center for Experimental (General Practice) Education, Xianning Medical College, Hubei University of Science and Technology, Xianning, Hubei, China., Cao Y; Xianning Central Hospital (The First Affiliated Hospital of Hubei University of Science and Technology), Xianning, Hubei, China.

Πηγή: Nephrology (Carlton, Vic.) [Nephrology (Carlton)] 2026 Aug; Vol. 31 (8), pp. e70237.

Τύπος έκδοσης: Journal Article

Στοιχεία περιοδικού: Publisher: Blackwell Science Country of Publication: Australia NLM ID: 9615568 Publication Model: Print Cited Medium: Internet ISSN: 1440-1797 (Electronic) Linking ISSN: 13205358 NLM ISO Abbreviation: Nephrology (Carlton) Subsets: MEDLINE

Ιατρικοί όροι (MeSH): Ferroptosis*/drug effects , Ferroptosis*/genetics , MicroRNAs*/metabolism , MicroRNAs*/genetics , Epithelial Cells*/pathology , Epithelial Cells*/enzymology , Kruppel-Like Transcription Factors*/metabolism , Kruppel-Like Transcription Factors*/genetics , Phospholipid Hydroperoxide Glutathione Peroxidase*/metabolism , Phospholipid Hydroperoxide Glutathione Peroxidase*/genetics , Diabetic Nephropathies*/pathology , Diabetic Nephropathies*/genetics , Diabetic Nephropathies*/enzymology , Sirtuin 3*/metabolism , Sirtuin 3*/genetics , Kidney Tubules*/pathology , Kidney Tubules*/enzymology, Glucose/toxicity ; Humans ; Kruppel-Like Factor 4 ; Signal Transduction ; Cell Line

SIRT3-activating, biodegradable poly-honokiol with high drug loading for thoracic aortic dissection therapy.

Συγγραφείς: Qiao X; Department of Cardiovascular Surgery, Xijing Hospital of Air Force Military Medical University, Xi'an, Shaanxi 710032, PR China., Wang D; School of Chemistry, Xi'an Jiaotong University, Xi'an, Shaanxi 710049, PR China., Zhu H; Department of Cardiovascular Surgery, Xijing Hospital of Air Force Military Medical University, Xi'an, Shaanxi 710032, PR China., Zhang B; Department of Cardiovascular Surgery, Xijing Hospital of Air Force Military Medical University, Xi'an, Shaanxi 710032, PR China., Sun H; Department of Cardiovascular Surgery, Xijing Hospital of Air Force Military Medical University, Xi'an, Shaanxi 710032, PR China., Wang J; School of Chemistry, Xi'an Jiaotong University, Xi'an, Shaanxi 710049, PR China., Tan G; School of Chemistry, Xi'an Jiaotong University, Xi'an, Shaanxi 710049, PR China., Jiang L; Department of Cardiovascular Surgery, Xijing Hospital of Air Force Military Medical University, Xi'an, Shaanxi 710032, PR China., Peng X; Department of Cardiovascular Surgery, Xijing Hospital of Air Force Military Medical University, Xi'an, Shaanxi 710032, PR China., Zhang L; Department of Cardiovascular Surgery, Xijing Hospital of Air Force Military Medical University, Xi'an, Shaanxi 710032, PR China., Wang L; Department of Cardiovascular Surgery, Xijing Hospital of Air Force Military Medical University, Xi'an, Shaanxi 710032, PR China., Han S; Department of Cardiovascular Surgery, Xijing Hospital of Air Force Military Medical University, Xi'an, Shaanxi 710032, PR China., Meng L; School of Chemistry, Xi'an Jiaotong University, Xi'an, Shaanxi 710049, PR China; Instrumental Analysis Center, Xi'an Jiaotong University, Xi'an, Shaanxi 710049, PR China. Electronic address: menglingjie@mail.xjtu.edu.cn., Duan W; Department of Cardiovascular Surgery, Xijing Hospital of Air Force Military Medical University, Xi'an, Shaanxi 710032, PR China. Electronic address: duanweixun@126.com.

Πηγή: Journal of advanced research [J Adv Res] 2026 Aug; Vol. 86, pp. 605-619. Date of Electronic Publication: 2025 Nov 14.

Τύπος έκδοσης: Journal Article

Στοιχεία περιοδικού: Publisher: Cairo University, production and hosting by Elsevier B. V Country of Publication: Egypt NLM ID: 101546952 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2090-1224 (Electronic) Linking ISSN: 20901224 NLM ISO Abbreviation: J Adv Res Subsets: MEDLINE

Ιατρικοί όροι (MeSH): Biphenyl Compounds*/pharmacology , Biphenyl Compounds*/chemistry , Lignans*/pharmacology , Lignans*/chemistry , Sirtuin 3*/metabolism , Aortic Dissection*/drug therapy , Aortic Dissection*/metabolism, Dissection, Thoracic Aorta/drug therapy ; Muscle, Smooth, Vascular/drug effects ; Muscle, Smooth, Vascular/metabolism ; Myocytes, Smooth Muscle/drug effects ; Myocytes, Smooth Muscle/metabolism ; Reactive Oxygen Species/metabolism ; Animals ; Phenols ; Mice ; Allyl Compounds ; Humans ; Male ; Disease Models, Animal

Advances in the Role of SIRT3 in Vascular Remodeling in Hypertension.

Συγγραφείς: Wahid A; International School of Medicine, Changsha Medical University, 1501 Leifeng Road, Changsha 410219, China.; Department of Cardiology of the Third Xiang-Ya Hospital, Central South University, 138 Tongzipo Road, Changsha 410013, China., Islam MT; Department of Biochemistry and Biotechnology, School of Biomedical Sciences, Khwaja Yunus Ali University, Sirajganj 6751, Bangladesh., Rana MS; Department of Biochemistry and Biotechnology, School of Biomedical Sciences, Khwaja Yunus Ali University, Sirajganj 6751, Bangladesh., Parvin MM; Department of Biochemistry and Biotechnology, School of Biomedical Sciences, Khwaja Yunus Ali University, Sirajganj 6751, Bangladesh., Weng C; Department of Cardiology of the Third Xiang-Ya Hospital, Central South University, 138 Tongzipo Road, Changsha 410013, China., Tang X; Department of Cardiology of the Third Xiang-Ya Hospital, Central South University, 138 Tongzipo Road, Changsha 410013, China.

Πηγή: Biomolecules [Biomolecules] 2026 Jul 16; Vol. 16 (7). Date of Electronic Publication: 2026 Jul 16.

Τύπος έκδοσης: Journal Article; Review

Στοιχεία περιοδικού: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101596414 Publication Model: Electronic Cited Medium: Internet ISSN: 2218-273X (Electronic) Linking ISSN: 2218273X NLM ISO Abbreviation: Biomolecules Subsets: MEDLINE

Ιατρικοί όροι (MeSH): Sirtuin 3*/metabolism , Sirtuin 3*/genetics , Hypertension*/metabolism , Hypertension*/pathology , Vascular Remodeling*, Mitochondria/metabolism ; Muscle, Smooth, Vascular/metabolism ; Humans ; Animals ; Oxidative Stress

SERPINE1 drives ferroptosis in acute respiratory distress syndrome by disrupting mitochondrial NAD⁺ homeostasis and suppressing Sirt3 activity.

Συγγραφείς: Gao N; China-Japan Friendship Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, People's Republic of China; Department of Emergency, China-Japan Friendship Hospital, Beijing, 100029, People's Republic of China., Zhang WJ; China-Japan Friendship Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, People's Republic of China; Department of Emergency, China-Japan Friendship Hospital, Beijing, 100029, People's Republic of China., Qian YX; China-Japan Friendship Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, People's Republic of China; Department of Emergency, China-Japan Friendship Hospital, Beijing, 100029, People's Republic of China., Yang S; China-Japan Friendship Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, People's Republic of China; Department of Emergency, China-Japan Friendship Hospital, Beijing, 100029, People's Republic of China., Zhang ZN; China-Japan Friendship Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, People's Republic of China; Graduate School, Peking University, Beijing, 100871, People's Republic of China., Lu HT; China-Japan Friendship Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, People's Republic of China; Department of Emergency, China-Japan Friendship Hospital, Beijing, 100029, People's Republic of China., Zhang GQ; Department of Emergency, China-Japan Friendship Hospital, Beijing, 100029, People's Republic of China. Electronic address: zhangchong2003@vip.sina.com.

Πηγή: Redox biology [Redox Biol] 2026 Jul; Vol. 94, pp. 104146. Date of Electronic Publication: 2026 Apr 15.

Τύπος έκδοσης: Journal Article; Research Support, Non-U.S. Gov't

Στοιχεία περιοδικού: Publisher: Elsevier, B.V Country of Publication: Netherlands NLM ID: 101605639 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2213-2317 (Electronic) Linking ISSN: 22132317 NLM ISO Abbreviation: Redox Biol Subsets: MEDLINE

Ιατρικοί όροι (MeSH): Respiratory Distress Syndrome*/metabolism , Respiratory Distress Syndrome*/pathology , Respiratory Distress Syndrome*/etiology , Respiratory Distress Syndrome*/genetics , Ferroptosis*/genetics , Mitochondria*/metabolism , Sirtuin 3*/metabolism , Sirtuin 3*/genetics , Plasminogen Activator Inhibitor 1*/metabolism , Plasminogen Activator Inhibitor 1*/genetics , NAD*/metabolism, Animals ; Mice ; Humans ; Homeostasis ; Disease Models, Animal

Honokiol protects against acute pancreatitis by activating SIRT3 to restore mitochondrial oxidative phosphorylation and alleviate hyperacetylation.

Συγγραφείς: Miao YF; Department of Emergency Medicine, Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu 610072, Sichuan Province, China., Yao JQ; Department of Integrated Traditional Chinese and Western Medicine, West China Hospital of Sichuan University, Chengdu 610041, Sichuan Province, China., Peng Y; School of Acupuncture and Tuina, Chengdu University of Traditional Chinese Medicine, Chengdu 611137, Sichuan Province, China., Bai D; School of Clinical Medicine, Chengdu University of Traditional Chinese Medicine, Chengdu 610072, Sichuan Province, China., Fan SH; School of Clinical Medicine, Chengdu University of Traditional Chinese Medicine, Chengdu 610072, Sichuan Province, China., Li HY; School of Clinical Medicine, Chengdu University of Traditional Chinese Medicine, Chengdu 610072, Sichuan Province, China., Jin W; Department of Emergency Medicine, Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu 610072, Sichuan Province, China., Lu Y; Department of Emergency Medicine, Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu 610072, Sichuan Province, China. Electronic address: 0550@cdutcm.edu.cn.

Πηγή: Journal of integrative medicine [J Integr Med] 2026 Jul; Vol. 24 (4), pp. 616-630. Date of Electronic Publication: 2026 Jan 28.

Τύπος έκδοσης: Journal Article

Στοιχεία περιοδικού: Publisher: Elsevier B.V Country of Publication: Netherlands NLM ID: 101603118 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2095-4964 (Print) NLM ISO Abbreviation: J Integr Med Subsets: MEDLINE

Ιατρικοί όροι (MeSH): Lignans*/pharmacology , Lignans*/administration & dosage , Biphenyl Compounds*/pharmacology , Biphenyl Compounds*/administration & dosage , Sirtuin 3*/metabolism , Sirtuin 3*/genetics , Oxidative Phosphorylation*/drug effects , Pancreatitis*/metabolism , Pancreatitis*/drug therapy , Pancreatitis*/prevention & control , Pancreatitis*/genetics , Mitochondria*/metabolism , Mitochondria*/drug effects, Acetylation/drug effects ; Phenols ; Allyl Compounds ; Animals ; Mice ; Male ; Humans ; Mice, Inbred C57BL

Chrysophanol ameliorates ferroptosis in acute kidney injury by promoting SIRT3-mediated NRF2 deacetylation.

Συγγραφείς: Cui M; The First Clinical College, Hubei University of Chinese Medicine, Wuhan, China.; Hubei Provincial Hospital of Traditional Chinese Medicine, 4 Garden 14 Hill Road, Wuchang District, Wuhan, 430000, Hubei, China.; Affiliated Hospital of Hubei University of Chinese Medicine, Wuhan, China.; Hubei Research Institute of Traditional Chinese Medicine, Wuhan, China.; Hubei Key Laboratory of Theory and Application Research of Liver and Kidney in Traditional Chinese Medicine, Wuhan, China., Tian H; Hubei Provincial Hospital of Traditional Chinese Medicine, 4 Garden 14 Hill Road, Wuchang District, Wuhan, 430000, Hubei, China.; Affiliated Hospital of Hubei University of Chinese Medicine, Wuhan, China.; Hubei Research Institute of Traditional Chinese Medicine, Wuhan, China.; Hubei Key Laboratory of Theory and Application Research of Liver and Kidney in Traditional Chinese Medicine, Wuhan, China., Zhu J; Hubei Provincial Hospital of Traditional Chinese Medicine, 4 Garden 14 Hill Road, Wuchang District, Wuhan, 430000, Hubei, China.; Affiliated Hospital of Hubei University of Chinese Medicine, Wuhan, China.; Hubei Research Institute of Traditional Chinese Medicine, Wuhan, China.; Hubei Key Laboratory of Theory and Application Research of Liver and Kidney in Traditional Chinese Medicine, Wuhan, China., Zhu J; Hubei Provincial Hospital of Traditional Chinese Medicine, 4 Garden 14 Hill Road, Wuchang District, Wuhan, 430000, Hubei, China. zhujing@hbhtcm.com.; Affiliated Hospital of Hubei University of Chinese Medicine, Wuhan, China. zhujing@hbhtcm.com.; Hubei Research Institute of Traditional Chinese Medicine, Wuhan, China. zhujing@hbhtcm.com.; Hubei Key Laboratory of Theory and Application Research of Liver and Kidney in Traditional Chinese Medicine, Wuhan, China. zhujing@hbhtcm.com., Wang Q; Hubei Provincial Hospital of Traditional Chinese Medicine, 4 Garden 14 Hill Road, Wuchang District, Wuhan, 430000, Hubei, China. 149806520@qq.com.; Affiliated Hospital of Hubei University of Chinese Medicine, Wuhan, China. 149806520@qq.com.; Hubei Research Institute of Traditional Chinese Medicine, Wuhan, China. 149806520@qq.com.; Hubei Key Laboratory of Theory and Application Research of Liver and Kidney in Traditional Chinese Medicine, Wuhan, China. 149806520@qq.com., Zou Y; Hubei Provincial Hospital of Traditional Chinese Medicine, 4 Garden 14 Hill Road, Wuchang District, Wuhan, 430000, Hubei, China. zouyinshui@hbhtcm.com.; Affiliated Hospital of Hubei University of Chinese Medicine, Wuhan, China. zouyinshui@hbhtcm.com.; Hubei Research Institute of Traditional Chinese Medicine, Wuhan, China. zouyinshui@hbhtcm.com.; Hubei Key Laboratory of Theory and Application Research of Liver and Kidney in Traditional Chinese Medicine, Wuhan, China. zouyinshui@hbhtcm.com.

Πηγή: Naunyn-Schmiedeberg's archives of pharmacology [Naunyn Schmiedebergs Arch Pharmacol] 2026 Jul; Vol. 399 (10), pp. 15941-15953. Date of Electronic Publication: 2026 May 05.

Τύπος έκδοσης: Journal Article

Στοιχεία περιοδικού: Publisher: Springer Verlag Country of Publication: Germany NLM ID: 0326264 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-1912 (Electronic) Linking ISSN: 00281298 NLM ISO Abbreviation: Naunyn Schmiedebergs Arch Pharmacol Subsets: MEDLINE

Ιατρικοί όροι (MeSH): NF-E2-Related Factor 2*/metabolism , Acute Kidney Injury*/drug therapy , Acute Kidney Injury*/metabolism , Acute Kidney Injury*/pathology , Acute Kidney Injury*/chemically induced , Ferroptosis*/drug effects , Sirtuin 3*/metabolism , Sirtuin 3*/genetics, Acetylation/drug effects ; Anti-Inflammatory Agents/pharmacology ; Animals ; Male ; Mice, Knockout ; Mice, Inbred C57BL ; Mice ; Lipopolysaccharides ; Anthraquinones

SIRT3-mediated mitochondrial fatty acid oxidation protects against hepatic lipid deposition in fatty liver hemorrhagic syndrome.

Συγγραφείς: Cao P; Jiangxi Provincial Key Laboratory for Animal Health, Institute of Animal Population Health, College of Animal Science and Technology, Jiangxi Agricultural University, Nanchang 330045, Jiangxi, PR China., Chen J; Jiangxi Provincial Key Laboratory for Animal Health, Institute of Animal Population Health, College of Animal Science and Technology, Jiangxi Agricultural University, Nanchang 330045, Jiangxi, PR China., Zeng C; Jiangxi Provincial Key Laboratory for Animal Health, Institute of Animal Population Health, College of Animal Science and Technology, Jiangxi Agricultural University, Nanchang 330045, Jiangxi, PR China., Hu Y; College of Computer and Information Engineering, Jiangxi Agricultural University, Nanchang 330045, Jiangxi, PR China., Yuan J; Jiangxi Provincial Key Laboratory for Animal Health, Institute of Animal Population Health, College of Animal Science and Technology, Jiangxi Agricultural University, Nanchang 330045, Jiangxi, PR China., Guo X; Jiangxi Provincial Key Laboratory for Animal Health, Institute of Animal Population Health, College of Animal Science and Technology, Jiangxi Agricultural University, Nanchang 330045, Jiangxi, PR China., Cao H; Jiangxi Provincial Key Laboratory for Animal Health, Institute of Animal Population Health, College of Animal Science and Technology, Jiangxi Agricultural University, Nanchang 330045, Jiangxi, PR China., Zhang C; Jiangxi Provincial Key Laboratory for Animal Health, Institute of Animal Population Health, College of Animal Science and Technology, Jiangxi Agricultural University, Nanchang 330045, Jiangxi, PR China., Zhuang Y; Jiangxi Provincial Key Laboratory for Animal Health, Institute of Animal Population Health, College of Animal Science and Technology, Jiangxi Agricultural University, Nanchang 330045, Jiangxi, PR China., Hu G; Jiangxi Provincial Key Laboratory for Animal Health, Institute of Animal Population Health, College of Animal Science and Technology, Jiangxi Agricultural University, Nanchang 330045, Jiangxi, PR China. Electronic address: hgljx3818@jxau.edu.cn.

Πηγή: Poultry science [Poult Sci] 2026 Jul; Vol. 105 (7), pp. 106901. Date of Electronic Publication: 2026 Apr 07.

Τύπος έκδοσης: Journal Article

Στοιχεία περιοδικού: Publisher: Elsevier Country of Publication: England NLM ID: 0401150 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1525-3171 (Electronic) Linking ISSN: 00325791 NLM ISO Abbreviation: Poult Sci Subsets: MEDLINE

Ιατρικοί όροι (MeSH): Sirtuin 3*/metabolism , Sirtuin 3*/genetics , Fatty Liver*/veterinary , Fatty Liver*/metabolism , Fatty Acids*/metabolism , Poultry Diseases*/metabolism , Avian Proteins*/metabolism , Avian Proteins*/genetics , Chickens* , Lipid Metabolism*, Liver/metabolism ; Diet/veterinary ; Hepatocytes/metabolism ; Mitochondria/metabolism ; Animals ; Oxidation-Reduction ; Female

Ethyl caffeate reprograms macrophage immunometabolism via the SIRT3-FOXO3A-AKT axis to enhance host defense against Candida auris.

Συγγραφείς: Yang X; Institute of Vascular Disease, Shanghai TCM-Integrated Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai 200082, China., Li J; Institute of Vascular Disease, Shanghai TCM-Integrated Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai 200082, China., Zhong Y; Institute of Vascular Disease, Shanghai TCM-Integrated Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai 200082, China., Shen Y; Institute of Vascular Disease, Shanghai TCM-Integrated Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai 200082, China., Xu C; Institute of Vascular Disease, Shanghai TCM-Integrated Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai 200082, China., Nie Z; Institute of Vascular Disease, Shanghai TCM-Integrated Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai 200082, China., Wang H; Institute of Vascular Disease, Shanghai TCM-Integrated Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai 200082, China., Cao R; Institute of Vascular Disease, Shanghai TCM-Integrated Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai 200082, China; School of Basic Medicine and Clinical Pharmacy, China Pharmaceutical University, Nanjing, Jiangsu 210008, China., Wang M; Institute of Vascular Disease, Shanghai TCM-Integrated Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai 200082, China., Zhang J; Institute of Vascular Disease, Shanghai TCM-Integrated Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai 200082, China., Ma C; Institute of Vascular Disease, Shanghai TCM-Integrated Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai 200082, China., Cai T; Shanghai Diacart Biomedical Science and Technology Limited Company, Shanghai 201203, China., Jia C; Institute of Vascular Disease, Shanghai TCM-Integrated Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai 200082, China., Wang R; Institute of Vascular Disease, Shanghai TCM-Integrated Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai 200082, China., Yin H; Institute of Vascular Disease, Shanghai TCM-Integrated Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai 200082, China. Electronic address: haoyin183@126.com., Chen J; Institute of Vascular Disease, Shanghai TCM-Integrated Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai 200082, China. Electronic address: alexandercj@126.com., Cao Y; Institute of Vascular Disease, Shanghai TCM-Integrated Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai 200082, China. Electronic address: ybcao@vip.sina.com.

Πηγή: International immunopharmacology [Int Immunopharmacol] 2026 Jul 01; Vol. 180, pp. 116651. Date of Electronic Publication: 2026 Apr 25.

Τύπος έκδοσης: Journal Article

Στοιχεία περιοδικού: Publisher: Elsevier Science Country of Publication: Netherlands NLM ID: 100965259 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1878-1705 (Electronic) Linking ISSN: 15675769 NLM ISO Abbreviation: Int Immunopharmacol Subsets: MEDLINE

Ιατρικοί όροι (MeSH): Macrophages*/immunology , Macrophages*/drug effects , Macrophages*/metabolism , Sirtuin 3*/metabolism , Sirtuin 3*/genetics , Candidiasis*/immunology , Candidiasis*/drug therapy , Candida*/immunology , Antifungal Agents*/pharmacology , Caffeic Acids*/pharmacology, Forkhead Box Protein O3/metabolism ; Proto-Oncogene Proteins c-akt/metabolism ; Signal Transduction/drug effects ; Phagocytosis/drug effects ; Animals ; Mice ; Mice, Inbred C57BL ; Mice, Knockout

Corylin promotes healthy aging via RAGA-mTOR suppression and sex-dependent activation of SIRT3.

Συγγραφείς: Cheng SF; Graduate Institute of Natural Products, Chang Gung University, Taoyuan, Taiwan, ROC., Lin YT; Molecular Medicine Research Center, Chang Gung University, Taoyuan, Taiwan, ROC., Wang TH; Graduate Institute of Natural Products, Chang Gung University, Taoyuan, Taiwan, ROC.; Biobank, Chang Gung Memorial Hospital, Taoyuan, Taiwan, ROC.; Department of Hepato-Gastroenterology, Liver Research Center, Chang Gung Memorial Hospital, Taoyuan, Taiwan, ROC.; Graduate Institute of Health Industry Technology and Research Center for Food and Cosmetic Safety, Chang Gung University of Science and Technology, Taoyuan, Taiwan, ROC., Leu YL; Graduate Institute of Natural Products, Chang Gung University, Taoyuan, Taiwan, ROC.; Biobank, Chang Gung Memorial Hospital, Taoyuan, Taiwan, ROC., Hsia KC; Institute of Molecular Biology, Academia Sinica, Taipei, Taiwan, ROC., Lee WC; Department and Graduate Institute of Pharmacology, National Taiwan University College of Medicine, Taipei, Taiwan, ROC.; Institute of Biomedical Science, Academia Sinica, Taipei, Taiwan, ROC., Feng CH; Graduate Institute of Natural Products, Chang Gung University, Taoyuan, Taiwan, ROC., Kuo CH; Institute of Biomedical Science, Academia Sinica, Taipei, Taiwan, ROC., Yang SH; School of Traditional Chinese Medicine, Chang Gung University, Taoyuan, Taiwan, ROC.; Division of Chinese Internal Medicine, Center for Traditional Chinese Medicine, Chang Gung Memorial Hospital, Taoyuan, Taiwan, ROC., Wang MC; School of Traditional Chinese Medicine, Chang Gung University, Taoyuan, Taiwan, ROC.; Division of Chinese Gynecology Medicine, Center for Traditional Chinese Medicine, Chang Gung Memorial Hospital, Taoyuan, Taiwan, ROC., Liu CY; Graduate Institute of Natural Products, Chang Gung University, Taoyuan, Taiwan, ROC., Hu PC; Graduate Institute of Natural Products, Chang Gung University, Taoyuan, Taiwan, ROC., Hsieh YC; Office of the Texas State Chemist, AgriLife Research, Texas A&M University System, College Station, TX, USA., Yang CW; Department of Nephrology and Kidney Research Center, School of Medicine, Chang Gung University, Chang Gung Memorial Hospital, Taoyuan, Taiwan, ROC., Wang SH; Department of Anatomy and Cell Biology, College of Medicine, National Taiwan University, Taipei, Taiwan, ROC., Yu JS; Molecular Medicine Research Center, Chang Gung University, Taoyuan, Taiwan, ROC. yusong@mail.cgu.edu.tw.; Department of Otolaryngology-Head & Neck Surgery, Chang Gung Memorial Hospital, Taoyuan, Taiwan, ROC. yusong@mail.cgu.edu.tw.; Research Center for Food and Cosmetic Safety, College of Human Ecology, Chang Gung University of Science and Technology, Taoyuan, Taiwan, ROC. yusong@mail.cgu.edu.tw., Chen CY; Biobank, Chang Gung Memorial Hospital, Taoyuan, Taiwan, ROC. cychen@mail.cgust.edu.tw.; Graduate Institute of Health Industry Technology and Research Center for Food and Cosmetic Safety, Chang Gung University of Science and Technology, Taoyuan, Taiwan, ROC. cychen@mail.cgust.edu.tw., Chen CC; Graduate Institute of Natural Products, Chang Gung University, Taoyuan, Taiwan, ROC. chinchuan@mail.cgu.edu.tw.; Biobank, Chang Gung Memorial Hospital, Taoyuan, Taiwan, ROC. chinchuan@mail.cgu.edu.tw.

Πηγή: Nature communications [Nat Commun] 2026 Jun 10; Vol. 17 (1). Date of Electronic Publication: 2026 Jun 10.

Τύπος έκδοσης: Journal Article

Στοιχεία περιοδικού: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

Ιατρικοί όροι (MeSH): TOR Serine-Threonine Kinases*/metabolism , TOR Serine-Threonine Kinases*/genetics , Sirtuin 3*/metabolism , Sirtuin 3*/genetics , Flavonoids*/pharmacology , Healthy Aging*/drug effects , Monomeric GTP-Binding Proteins*/metabolism , Monomeric GTP-Binding Proteins*/genetics, Longevity/drug effects ; Signal Transduction/drug effects ; Animals ; Female ; Male ; Mice ; Mice, Inbred C57BL ; Sex Factors

Cornuside alleviates microglia-mediated neuroinflammation to ameliorate chronic neuropathic pain-induced cognitive impairment via the Nrf2/Sirt3 signaling pathway.

Συγγραφείς: Yin J; Department of Pediatrics, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China; Department of Anesthesiology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, 430030, China., Chu L; Department of Pathophysiology, School of Basic Medicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, 430030, China., Chen Y; Department of Anesthesiology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, 430030, China., Fan L; Department of Anesthesiology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, 430030, China., Wang X; Department of Anesthesiology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, 430030, China., Wen Y; Department of Pediatrics, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China., He L; Department of Pediatrics, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China. Electronic address: 2025TJ0059@hust.edu.cn.

Πηγή: Free radical biology & medicine [Free Radic Biol Med] 2026 Jun; Vol. 249, pp. 292-307. Date of Electronic Publication: 2026 Mar 12.

Τύπος έκδοσης: Journal Article

Στοιχεία περιοδικού: Publisher: Elsevier Science Country of Publication: United States NLM ID: 8709159 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-4596 (Electronic) Linking ISSN: 08915849 NLM ISO Abbreviation: Free Radic Biol Med Subsets: MEDLINE

Ιατρικοί όροι (MeSH): Microglia*/drug effects , Microglia*/pathology , Microglia*/metabolism , NF-E2-Related Factor 2*/metabolism , NF-E2-Related Factor 2*/genetics , Neuralgia*/drug therapy , Neuralgia*/complications , Neuralgia*/pathology , Cognitive Dysfunction*/drug therapy , Cognitive Dysfunction*/etiology , Cognitive Dysfunction*/pathology , Cognitive Dysfunction*/metabolism , Sirtuin 3*/metabolism , Sirtuin 3*/genetics , Glycosides*/pharmacology , Neuroinflammatory Diseases*/drug therapy , Neuroinflammatory Diseases*/pathology , Flavonoids*/pharmacology , Chronic Pain*/drug therapy , Chronic Pain*/complications, Signal Transduction/drug effects ; Cornus/chemistry ; Inflammation/drug therapy ; Animals ; Mice ; Male ; Humans ; Disease Models, Animal ; Glucosides ; Pyrans

Hyperacetylation escalates myocardial susceptibility to ischemia reperfusion injury by mediating mitochondrial supercomplexes assembly in T2DM.

Συγγραφείς: Deng Y; Department of Anesthesiology, National-Local Joint Engineering Research Centre of Translational Medicine of Anesthesiology, West China Hospital of Sichuan University, Chengdu, 610041, China; Laboratory of Mitochondrial Metabolism and Perioperative Medicine, National Clinical Research Center for Geriatrics, West China Hospital of Sichuan University, Chengdu, 610041, China., Yang W; Department of Anesthesiology, National-Local Joint Engineering Research Centre of Translational Medicine of Anesthesiology, West China Hospital of Sichuan University, Chengdu, 610041, China; Laboratory of Mitochondrial Metabolism and Perioperative Medicine, National Clinical Research Center for Geriatrics, West China Hospital of Sichuan University, Chengdu, 610041, China., Yang J; Laboratory of Mitochondrial Metabolism and Perioperative Medicine, National Clinical Research Center for Geriatrics, West China Hospital of Sichuan University, Chengdu, 610041, China., Ji L; Department of Anesthesiology, National-Local Joint Engineering Research Centre of Translational Medicine of Anesthesiology, West China Hospital of Sichuan University, Chengdu, 610041, China; Laboratory of Mitochondrial Metabolism and Perioperative Medicine, National Clinical Research Center for Geriatrics, West China Hospital of Sichuan University, Chengdu, 610041, China., Xie M; Laboratory of Mitochondrial Metabolism and Perioperative Medicine, National Clinical Research Center for Geriatrics, West China Hospital of Sichuan University, Chengdu, 610041, China., Tang K; Laboratory of Mitochondrial Metabolism and Perioperative Medicine, National Clinical Research Center for Geriatrics, West China Hospital of Sichuan University, Chengdu, 610041, China., He Q; Department of Anesthesiology, National-Local Joint Engineering Research Centre of Translational Medicine of Anesthesiology, West China Hospital of Sichuan University, Chengdu, 610041, China; Laboratory of Mitochondrial Metabolism and Perioperative Medicine, National Clinical Research Center for Geriatrics, West China Hospital of Sichuan University, Chengdu, 610041, China., Hu G; Department of Anesthesiology, University of Illinois College of Medicine, Chicago, IL, USA., Shangguan W; Department of Anesthesiology and Perioperative Medicine, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, 325027, China. Electronic address: sgwning@163.com., Jiang C; Department of Anesthesiology, National-Local Joint Engineering Research Centre of Translational Medicine of Anesthesiology, West China Hospital of Sichuan University, Chengdu, 610041, China; Laboratory of Mitochondrial Metabolism and Perioperative Medicine, National Clinical Research Center for Geriatrics, West China Hospital of Sichuan University, Chengdu, 610041, China. Electronic address: jiangchunling@scu.edu.cn., Li T; Department of Anesthesiology, National-Local Joint Engineering Research Centre of Translational Medicine of Anesthesiology, West China Hospital of Sichuan University, Chengdu, 610041, China; Laboratory of Mitochondrial Metabolism and Perioperative Medicine, National Clinical Research Center for Geriatrics, West China Hospital of Sichuan University, Chengdu, 610041, China. Electronic address: scutaoli1981@scu.edu.cn.

Πηγή: Redox biology [Redox Biol] 2026 Jun; Vol. 93, pp. 104163. Date of Electronic Publication: 2026 Apr 08.

Τύπος έκδοσης: Journal Article

Στοιχεία περιοδικού: Publisher: Elsevier, B.V Country of Publication: Netherlands NLM ID: 101605639 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2213-2317 (Electronic) Linking ISSN: 22132317 NLM ISO Abbreviation: Redox Biol Subsets: MEDLINE

Ιατρικοί όροι (MeSH): Sirtuin 3*/genetics , Sirtuin 3*/metabolism , Sirtuin 3*/deficiency , Myocardial Reperfusion Injury*/metabolism , Myocardial Reperfusion Injury*/pathology , Myocardial Reperfusion Injury*/etiology , Myocardial Reperfusion Injury*/genetics , Diabetes Mellitus, Type 2*/metabolism , Diabetes Mellitus, Type 2*/complications , Diabetes Mellitus, Type 2*/pathology , Diabetes Mellitus, Type 2*/genetics , Mitochondria, Heart*/metabolism , Mitochondria*/metabolism, Reactive Oxygen Species/metabolism ; Mitochondrial Proteins/metabolism ; Myocardium/metabolism ; Myocardium/pathology ; Diabetes Mellitus, Experimental/metabolism ; Animals ; Acetylation ; Mice ; Mice, Knockout ; Male ; Disease Susceptibility ; Disease Models, Animal

Hyperglycemia-induced SIRT3 inhibition contributes to diabetic cardiomyopathy by impairing Cav-3-mediated mitophagy.

Συγγραφείς: Jin Z; Department of Anesthesiology, Renmin Hospital of Wuhan University, Wuhan, China., Ji Y; Department of Anesthesiology, Renmin Hospital of Wuhan University, Wuhan, China., Su W; Department of Anesthesiology, Renmin Hospital of Wuhan University, Wuhan, China., Zhou L; Department of Anesthesiology, Renmin Hospital of Wuhan University, Wuhan, China., Gao L; Department of Anesthesiology, Renmin Hospital of Wuhan University, Wuhan, China., Wen X; Department of Anesthesiology, Renmin Hospital of Wuhan University, Wuhan, China., Tang H; Department of Anesthesiology, Renmin Hospital of Wuhan University, Wuhan, China., Xia ZY; Department of Anesthesiology, Renmin Hospital of Wuhan University, Wuhan, China., Lei S; Department of Anesthesiology, Renmin Hospital of Wuhan University, Wuhan, China. Electronic address: leishaoqing@163.com.

Πηγή: Biochemical pharmacology [Biochem Pharmacol] 2026 Jun; Vol. 248, pp. 117835. Date of Electronic Publication: 2026 Feb 20.

Τύπος έκδοσης: Journal Article

Στοιχεία περιοδικού: Publisher: Elsevier Science Country of Publication: England NLM ID: 0101032 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-2968 (Electronic) Linking ISSN: 00062952 NLM ISO Abbreviation: Biochem Pharmacol Subsets: MEDLINE

Ιατρικοί όροι (MeSH): Sirtuin 3*/antagonists & inhibitors , Sirtuin 3*/metabolism , Sirtuin 3*/genetics , Diabetic Cardiomyopathies*/metabolism , Diabetic Cardiomyopathies*/pathology , Mitophagy*/physiology , Mitophagy*/drug effects , Caveolin 3*/metabolism , Caveolin 3*/genetics , Caveolin 3*/antagonists & inhibitors , Hyperglycemia*/metabolism , Hyperglycemia*/pathology, Myocytes, Cardiac/metabolism ; Myocytes, Cardiac/drug effects ; Myocytes, Cardiac/pathology ; Diabetes Mellitus, Experimental/metabolism ; Animals ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; Male ; Rats ; Cell Line

SIRT3 ameliorates hepatic inflammation, oxidative stress, and fibrosis in HFD- or MCD diet-fed mice.

Συγγραφείς: Lv H; Department of Nutrition and Food Hygiene, School of Public Health, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, China., Sun W; Department of Nutrition and Food Hygiene, School of Public Health, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, China., Tian C; Department of Nutrition and Food Hygiene, School of Public Health, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, China., Bian C; Department of Nutrition and Food Hygiene, School of Public Health, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, China., Lu Z; Department of Nutrition and Food Hygiene, School of Public Health, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, China., Guo X; Department of Nutrition and Food Hygiene, School of Public Health, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, China. Electronic address: xguo@sdu.edu.cn.

Πηγή: The Journal of nutritional biochemistry [J Nutr Biochem] 2026 Jun; Vol. 152, pp. 110276. Date of Electronic Publication: 2026 Jan 29.

Τύπος έκδοσης: Journal Article

Στοιχεία περιοδικού: Publisher: Elsevier Science Country of Publication: United States NLM ID: 9010081 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-4847 (Electronic) Linking ISSN: 09552863 NLM ISO Abbreviation: J Nutr Biochem Subsets: MEDLINE

Ιατρικοί όροι (MeSH): Sirtuin 3*/metabolism , Sirtuin 3*/genetics , Diet, High-Fat*/adverse effects , Liver Cirrhosis*/metabolism , Oxidative Stress*, Liver/metabolism ; Liver/pathology ; Inflammation/metabolism ; Animals ; Male ; Mice, Inbred C57BL ; Mice

Benzalkonium chlorides compromise oocyte maturation and developmental competence by disrupting mitochondrial function and the SIRT3-SOD2 antioxidant axis.

Συγγραφείς: Lay K; College of Animal Science and Technology, Anhui Agricultural University, Key Laboratory of Local Livestock and Poultry Genetical Resource Conservation and Breeding of Anhui Province, Hefei 230036, China., Zhang D; Department of Reproductive Medicine, Wanbei Coal and Electricity Group General Hospital, Key Laboratory of Reproductive Medicine and Embryo of Suzhou city, Suzhou 234000, China., Wang H; College of Animal Science and Technology, Anhui Agricultural University, Key Laboratory of Local Livestock and Poultry Genetical Resource Conservation and Breeding of Anhui Province, Hefei 230036, China., Li M; College of Animal Science and Technology, Anhui Agricultural University, Key Laboratory of Local Livestock and Poultry Genetical Resource Conservation and Breeding of Anhui Province, Hefei 230036, China., Zhang Y; College of Animal Science and Technology, Anhui Agricultural University, Key Laboratory of Local Livestock and Poultry Genetical Resource Conservation and Breeding of Anhui Province, Hefei 230036, China., Xu Q; College of Animal Science and Technology, Anhui Agricultural University, Key Laboratory of Local Livestock and Poultry Genetical Resource Conservation and Breeding of Anhui Province, Hefei 230036, China., Jia B; College of Animal Science and Technology, Anhui Agricultural University, Key Laboratory of Local Livestock and Poultry Genetical Resource Conservation and Breeding of Anhui Province, Hefei 230036, China., Nguyen T; Branch of Animal Husbandry, Veterinary Medicine and Fisheries in Binh Duong Province, Vietnam., Ren C; College of Animal Science and Technology, Anhui Agricultural University, Key Laboratory of Local Livestock and Poultry Genetical Resource Conservation and Breeding of Anhui Province, Hefei 230036, China., Zhou X; Department of Reproductive Medicine, Wanbei Coal and Electricity Group General Hospital, Key Laboratory of Reproductive Medicine and Embryo of Suzhou city, Suzhou 234000, China., Tang H; Department of Reproductive Medicine, Wanbei Coal and Electricity Group General Hospital, Key Laboratory of Reproductive Medicine and Embryo of Suzhou city, Suzhou 234000, China., Ling Y; College of Animal Science and Technology, Anhui Agricultural University, Key Laboratory of Local Livestock and Poultry Genetical Resource Conservation and Breeding of Anhui Province, Hefei 230036, China., Wu M; School of Biology and Food Engineering, Hefei Normal University, Hefei 230061, China., Gao Y; School of Biology and Food Engineering, Hefei Normal University, Hefei 230061, China. Electronic address: gaoyang@hfnu.edu.cn., Zhang M; College of Animal Science and Technology, Anhui Agricultural University, Key Laboratory of Local Livestock and Poultry Genetical Resource Conservation and Breeding of Anhui Province, Hefei 230036, China. Electronic address: zhangmianqun@ahau.edu.cn., Zhang Y; College of Animal Science and Technology, Anhui Agricultural University, Key Laboratory of Local Livestock and Poultry Genetical Resource Conservation and Breeding of Anhui Province, Hefei 230036, China. Electronic address: dkzyh@ahau.edu.cn.

Πηγή: Animal reproduction science [Anim Reprod Sci] 2026 Jun; Vol. 289, pp. 108163. Date of Electronic Publication: 2026 Mar 03.

Τύπος έκδοσης: Journal Article

Στοιχεία περιοδικού: Publisher: Elsevier Scientific Pub. Co Country of Publication: Netherlands NLM ID: 7807205 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-2232 (Electronic) Linking ISSN: 03784320 NLM ISO Abbreviation: Anim Reprod Sci Subsets: MEDLINE

Ιατρικοί όροι (MeSH): Mitochondria*/drug effects , Mitochondria*/physiology , Oocytes*/drug effects , Benzalkonium Compounds*/toxicity , Superoxide Dismutase*/metabolism , Superoxide Dismutase*/genetics , Sirtuin 3*/metabolism , Sirtuin 3*/genetics, In Vitro Oocyte Maturation Techniques/veterinary ; Antioxidants/metabolism ; Oxidative Stress/drug effects ; Animals ; Female ; Swine ; Superoxide Dismutase 2

Hyaluronic acid-coated metal-organic framework for co-delivery of Sirtuin 3 gene and zinc to inhibit liver fibrosis.

Συγγραφείς: Jung J; Department of Biotechnology, The Catholic University of Korea, 43 Jibong-ro, Wonmi-gu, Bucheon-si, Gyeonggi-do 14662, Republic of Korea; Department of Biomedical-Chemical Engineering, The Catholic University of Korea, 43 Jibong-ro, Wonmi-gu, Bucheon-si, Gyeonggi-do 14662, Republic of Korea., Jin M; Department of Biotechnology, The Catholic University of Korea, 43 Jibong-ro, Wonmi-gu, Bucheon-si, Gyeonggi-do 14662, Republic of Korea; Department of Biomedical-Chemical Engineering, The Catholic University of Korea, 43 Jibong-ro, Wonmi-gu, Bucheon-si, Gyeonggi-do 14662, Republic of Korea., Park N; Department of Nanomedical Engineering, Korea National University of Transportation, 50 Daehak-ro, Chungju-si, Chungcheongbuk-do 27469, Republic of Korea., Choi H; Department of Biotechnology, The Catholic University of Korea, 43 Jibong-ro, Wonmi-gu, Bucheon-si, Gyeonggi-do 14662, Republic of Korea; Department of Biomedical-Chemical Engineering, The Catholic University of Korea, 43 Jibong-ro, Wonmi-gu, Bucheon-si, Gyeonggi-do 14662, Republic of Korea., Na K; Department of Biotechnology, The Catholic University of Korea, 43 Jibong-ro, Wonmi-gu, Bucheon-si, Gyeonggi-do 14662, Republic of Korea; Department of Biomedical-Chemical Engineering, The Catholic University of Korea, 43 Jibong-ro, Wonmi-gu, Bucheon-si, Gyeonggi-do 14662, Republic of Korea. Electronic address: kna6997@catholic.ac.kr.

Πηγή: Acta biomaterialia [Acta Biomater] 2026 Aug; Vol. 219, pp. 510-525. Date of Electronic Publication: 2026 Jun 17.

Τύπος έκδοσης: Journal Article

Στοιχεία περιοδικού: Publisher: Elsevier Country of Publication: England NLM ID: 101233144 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1878-7568 (Electronic) Linking ISSN: 17427061 NLM ISO Abbreviation: Acta Biomater Subsets: MEDLINE

Ιατρικοί όροι (MeSH): Hyaluronic Acid*/chemistry , Hyaluronic Acid*/pharmacology , Zinc*/pharmacology , Zinc*/chemistry , Liver Cirrhosis*/pathology , Liver Cirrhosis*/therapy , Liver Cirrhosis*/genetics , Liver Cirrhosis*/metabolism , Sirtuin 3*/genetics , Gene Transfer Techniques*, Hepatic Stellate Cells/metabolism ; Hepatic Stellate Cells/pathology ; Imidazoles/chemistry ; Imidazoles/pharmacology ; Macrophages/metabolism ; Macrophages/pathology ; Endothelial Cells/metabolism ; Animals ; Mice ; Male ; Gene Therapy Agents ; Mice, Inbred C57BL ; Plasmids ; Metal-Organic Frameworks

Humanin improved the rotenone-induced reactive oxygen species formation in PC12 cells by modulating the SIRT3/Nrf2/HO-1 signaling pathway.

Συγγραφείς: Shan Y; The Institute of Toxicology, The Department of Preventive Medicine, The Third Military Medical University, Chongqing, China., Liu X; The Institute of Toxicology, The Department of Preventive Medicine, The Third Military Medical University, Chongqing, China., Ge W; The Institute of Toxicology, The Department of Preventive Medicine, The Third Military Medical University, Chongqing, China., Zhang Q; The Institute of Toxicology, The Department of Preventive Medicine, The Third Military Medical University, Chongqing, China., Yan S; The Institute of Toxicology, The Department of Preventive Medicine, The Third Military Medical University, Chongqing, China.

Πηγή: Toxicology and industrial health [Toxicol Ind Health] 2026 Aug; Vol. 42 (8), pp. 275-283. Date of Electronic Publication: 2026 Apr 27.

Τύπος έκδοσης: Journal Article

Στοιχεία περιοδικού: Publisher: SAGE Publications Country of Publication: England NLM ID: 8602702 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1477-0393 (Electronic) Linking ISSN: 07482337 NLM ISO Abbreviation: Toxicol Ind Health Subsets: MEDLINE

Ιατρικοί όροι (MeSH): Rotenone*/toxicity , Reactive Oxygen Species*/metabolism , NF-E2-Related Factor 2*/metabolism , Sirtuin 3*/metabolism, Signal Transduction/drug effects ; Cell Survival/drug effects ; Oxidative Stress/drug effects ; Heme Oxygenase-1/metabolism ; Heme Oxygenase (Decyclizing)/metabolism ; Animals ; PC12 Cells ; Rats ; Sirtuins