SIRT3 in post-myocardial infarction macrophage reprogramming: linking mitochondrial fitness to inflammation resolution and repair.

Authors: Li X; Qihuang College, Guizhou University of Traditional Chinese Medicine, Guiyang, China., Luo X; School of Basic Medicine, Guizhou University of Traditional Chinese Medicine, Guiyang, China., Zhang Z; School of Basic Medicine, Guizhou University of Traditional Chinese Medicine, Guiyang, China., Tang L; School of Basic Medicine, Guizhou University of Traditional Chinese Medicine, Guiyang, China., Meng X; Qihuang College, Guizhou University of Traditional Chinese Medicine, Guiyang, China.

Source: Frontiers in immunology [Front Immunol] 2026 Jul 08; Vol. 17, pp. 1848626. Date of Electronic Publication: 2026 Jul 08 (Print Publication: 2026).

Publication Type: Journal Article; Review; Systematic Review

Journal Info: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101560960 Publication Model: eCollection Cited Medium: Internet ISSN: 1664-3224 (Electronic) Linking ISSN: 16643224 NLM ISO Abbreviation: Front Immunol Subsets: MEDLINE

MeSH Terms: Macrophages*/metabolism , Macrophages*/immunology , Myocardial Infarction*/metabolism , Myocardial Infarction*/pathology , Myocardial Infarction*/immunology , Sirtuin 3*/metabolism , Mitochondria*/metabolism , Cellular Reprogramming*, Inflammation/metabolism ; Inflammation/immunology ; Reactive Oxygen Species/metabolism ; Humans ; Animals ; Efferocytosis ; Metabolic Reprogramming

Spatial-Niche Perspective on the Heterogeneity and Functional Reprogramming of Tumor-Associated Macrophages in Digestive System Tumors.

Authors: Zhang J; School of Basic Medical Sciences, Zhejiang Chinese Medical University, Hangzhou 310053, China.; Zhejiang Key Laboratory of Blood-Stasis-Toxin Syndrome, Zhejiang Chinese Medical University, Hangzhou 310053, China., Huang Y; School of Basic Medical Sciences, Zhejiang Chinese Medical University, Hangzhou 310053, China.; Zhejiang Key Laboratory of Blood-Stasis-Toxin Syndrome, Zhejiang Chinese Medical University, Hangzhou 310053, China., Zhang M; School of Basic Medical Sciences, Zhejiang Chinese Medical University, Hangzhou 310053, China.; Zhejiang Key Laboratory of Blood-Stasis-Toxin Syndrome, Zhejiang Chinese Medical University, Hangzhou 310053, China., Lou J; School of Basic Medical Sciences, Zhejiang Chinese Medical University, Hangzhou 310053, China.; Zhejiang Key Laboratory of Blood-Stasis-Toxin Syndrome, Zhejiang Chinese Medical University, Hangzhou 310053, China., Zhang S; School of Basic Medical Sciences, Zhejiang Chinese Medical University, Hangzhou 310053, China.; Zhejiang Key Laboratory of Blood-Stasis-Toxin Syndrome, Zhejiang Chinese Medical University, Hangzhou 310053, China., Zhao S; School of Basic Medical Sciences, Zhejiang Chinese Medical University, Hangzhou 310053, China.; Zhejiang Key Laboratory of Blood-Stasis-Toxin Syndrome, Zhejiang Chinese Medical University, Hangzhou 310053, China., Song Z; School of Basic Medical Sciences, Zhejiang Chinese Medical University, Hangzhou 310053, China.; Zhejiang Key Laboratory of Blood-Stasis-Toxin Syndrome, Zhejiang Chinese Medical University, Hangzhou 310053, China., Zhang K; School of Basic Medical Sciences, Zhejiang Chinese Medical University, Hangzhou 310053, China.; Zhejiang Key Laboratory of Blood-Stasis-Toxin Syndrome, Zhejiang Chinese Medical University, Hangzhou 310053, China., Jiang T; School of Basic Medical Sciences, Zhejiang Chinese Medical University, Hangzhou 310053, China.; Zhejiang Key Laboratory of Blood-Stasis-Toxin Syndrome, Zhejiang Chinese Medical University, Hangzhou 310053, China.; Traditional Chinese Medicine 'Preventing Disease' Wisdom Health Project Research Center of Zhejiang, Hangzhou 310053, China., Zhang G; School of Basic Medical Sciences, Zhejiang Chinese Medical University, Hangzhou 310053, China.; Zhejiang Key Laboratory of Blood-Stasis-Toxin Syndrome, Zhejiang Chinese Medical University, Hangzhou 310053, China.; Traditional Chinese Medicine 'Preventing Disease' Wisdom Health Project Research Center of Zhejiang, Hangzhou 310053, China.

Source: Cells [Cells] 2026 Jul 01; Vol. 15 (13). Date of Electronic Publication: 2026 Jul 01.

Publication Type: Journal Article; Review

Journal Info: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101600052 Publication Model: Electronic Cited Medium: Internet ISSN: 2073-4409 (Electronic) Linking ISSN: 20734409 NLM ISO Abbreviation: Cells Subsets: MEDLINE

MeSH Terms: Tumor-Associated Macrophages*/pathology , Tumor-Associated Macrophages*/metabolism , Digestive System Neoplasms*/pathology , Digestive System Neoplasms*/immunology , Digestive System Neoplasms*/metabolism , Tumor Microenvironment* , Cellular Reprogramming*, Humans ; Animals ; Metabolic Reprogramming

Integrated stress response couples mitochondrial fitness with lineage reprogramming to drive cancer evolution.

Authors: Diao S; Lady Davis Institute for Medical Research, Sir Mortimer B. Davis Jewish General Hospital, Montreal, Quebec, Canada.; Graduate Program in Clinical and Translational Research, Faculty of Medicine, McGill University, Montreal, Quebec, Canada., Zou JY; Lady Davis Institute for Medical Research, Sir Mortimer B. Davis Jewish General Hospital, Montreal, Quebec, Canada.; Graduate Program in Clinical and Translational Research, Faculty of Medicine, McGill University, Montreal, Quebec, Canada., Wang S; Lady Davis Institute for Medical Research, Sir Mortimer B. Davis Jewish General Hospital, Montreal, Quebec, Canada., Chan JE; Cancer Biology and Genetics Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.; Division of Solid Tumor Oncology, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Kortlever RM; The Francis Crick Institute, London, UK.; King's College London, London, UK., Poulain N; Cancer Research UK Scotland Institute, Garscube Estate, Glasgow, UK., Ghaddar N; Lady Davis Institute for Medical Research, Sir Mortimer B. Davis Jewish General Hospital, Montreal, Quebec, Canada., Kim H; Lady Davis Institute for Medical Research, Sir Mortimer B. Davis Jewish General Hospital, Montreal, Quebec, Canada.; Graduate Program in Clinical and Translational Research, Faculty of Medicine, McGill University, Montreal, Quebec, Canada., Evan GI; The Francis Crick Institute, London, UK.; King's College London, London, UK., Koumenis C; Department of Radiation Oncology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA., Hatzoglou M; Department of Genetics and Genome Sciences, Case Western Reserve University, Cleveland, OH, USA., Walter P; Altos Laboratories, Bay Area Institute of Science, Redwood City, CA, USA., Sonenberg N; Department of Biochemistry, McGill University, Montreal, Quebec, Canada.; Rosalind and Morris Goodman Cancer Institute, Montreal, Quebec, Canada., Le Quesne J; Cancer Research UK Scotland Institute, Garscube Estate, Glasgow, UK.; School of Cancer Sciences, University of Glasgow, Glasgow, UK.; Queen Elizabeth University Hospital, Greater Glasgow and Clyde NHS Trust, Glasgow, UK., Tammela T; Cancer Biology and Genetics Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Koromilas AE; Lady Davis Institute for Medical Research, Sir Mortimer B. Davis Jewish General Hospital, Montreal, Quebec, Canada. antonis.koromilas@mcgill.ca.; Graduate Program in Clinical and Translational Research, Faculty of Medicine, McGill University, Montreal, Quebec, Canada. antonis.koromilas@mcgill.ca.; Gerald Bronfman Department of Oncology, Faculty of Medicine, McGill University, Montreal, Quebec, Canada. antonis.koromilas@mcgill.ca.

Source: Nature cell biology [Nat Cell Biol] 2026 Jul; Vol. 28 (7), pp. 1529-1544. Date of Electronic Publication: 2026 Jun 15.

Publication Type: Journal Article

Journal Info: Publisher: Macmillan Magazines Ltd Country of Publication: England NLM ID: 100890575 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-4679 (Electronic) Linking ISSN: 14657392 NLM ISO Abbreviation: Nat Cell Biol Subsets: MEDLINE

MeSH Terms: Mitochondria*/metabolism , Mitochondria*/pathology , Mitochondria*/genetics , Lung Neoplasms*/pathology , Lung Neoplasms*/genetics , Lung Neoplasms*/metabolism , Adenocarcinoma*/pathology , Adenocarcinoma*/genetics , Adenocarcinoma*/metabolism , Integrated Stress Response* , Cell Lineage* , Cellular Reprogramming*, Activating Transcription Factor 4/metabolism ; Activating Transcription Factor 4/genetics ; Adenocarcinoma of Lung/pathology ; Adenocarcinoma of Lung/genetics ; Adenocarcinoma of Lung/metabolism ; Eukaryotic Initiation Factor-2/metabolism ; Eukaryotic Initiation Factor-2/genetics ; Proto-Oncogene Proteins c-myc/metabolism ; Proto-Oncogene Proteins c-myc/genetics ; Transcription Factors/metabolism ; Transcription Factors/genetics ; Animals ; Humans ; Epithelial-Mesenchymal Transition ; Mice ; Cell Line, Tumor ; Metabolic Reprogramming ; Gene Expression Regulation, Neoplastic ; Phosphorylation ; Signal Transduction ; Cell Dedifferentiation ; Thyroid Nuclear Factor 1

[Molecular mechanism of intervertebral disc cell senescence: telomeres, mitochondria, and cellular metabolic reprogramming].

Authors: Deng W; Guangzhou University of Chinese Medicine, Guangzhou 510006, China.; Department of Minimally Invasive Spine Surgery, The First Clinical Medical College of Guangzhou University of Chinese Medicine/The First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou 510006, China., Zhu RC; Guangzhou University of Chinese Medicine, Guangzhou 510006, China.; Department of Minimally Invasive Spine Surgery, The First Clinical Medical College of Guangzhou University of Chinese Medicine/The First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou 510006, China., Kong FG; The Second Department of Minimally Invasive Spine Surgery, Luoyang Orthopedic Hospital of Henan Province/Orthopedic Hospital of Henan Province, Zhengzhou 450000, China., Luan JY; Guangzhou University of Chinese Medicine, Guangzhou 510006, China.; The Second Department of Minimally Invasive Spine Surgery, Luoyang Orthopedic Hospital of Henan Province/Orthopedic Hospital of Henan Province, Zhengzhou 450000, China.

Source: Sheng li xue bao : [Acta physiologica Sinica] [Sheng Li Xue Bao] 2026 Jun 25; Vol. 78 (3), pp. 566-578.

Publication Type: Journal Article; Review; English Abstract

Journal Info: Publisher: Science Press Country of Publication: China NLM ID: 20730130R Publication Model: Print Cited Medium: Internet ISSN: 0371-0874 (Print) Linking ISSN: 03710874 NLM ISO Abbreviation: Sheng Li Xue Bao Subsets: MEDLINE

MeSH Terms: Cellular Senescence*/physiology , Cellular Senescence*/genetics , Mitochondria*/physiology , Mitochondria*/metabolism , Telomere*/physiology , Intervertebral Disc Degeneration*/metabolism , Intervertebral Disc Degeneration*/pathology , Intervertebral Disc*/cytology , Intervertebral Disc*/metabolism , Cellular Reprogramming*, Humans ; Metabolic Reprogramming ; Animals

Tumour endothelial cell reprogramming orchestrates angiocrine signalling to drive chemoresistance in breast cancer.

Authors: Gomez-Escudero J; Barts Cancer Institute, Queen Mary University of London, Charterhouse Square, London, UK. jesuschgoes@usal.es.; Biochemistry and Molecular Biology Department, Salamanca University, Salamanca, Spain. jesuschgoes@usal.es., Maniati E; Barts Cancer Institute, Queen Mary University of London, Charterhouse Square, London, UK., Holdsworth J; Barts Cancer Institute, Queen Mary University of London, Charterhouse Square, London, UK., Beattie G; UCL Cancer Institute, CRUK City of London Centre Single Cell Genomics Facility, University College London, London, UK.; Bioinformatics Hub, UCL Cancer Institute, University College London, London, UK., Hijazi M; Barts Cancer Institute, Queen Mary University of London, Charterhouse Square, London, UK.; Biochemistry and Molecular Biology Department, Salamanca University, Salamanca, Spain., Guelbert M; Division of Cancer Biology, The Institute of Cancer Research, London, UK., Elorbany S; Barts Cancer Institute, Queen Mary University of London, Charterhouse Square, London, UK., Cutillas P; Barts Cancer Institute, Queen Mary University of London, Charterhouse Square, London, UK., Wang J; Barts Cancer Institute, Queen Mary University of London, Charterhouse Square, London, UK., Hodivala-Dilke K; Barts Cancer Institute, Queen Mary University of London, Charterhouse Square, London, UK. k.hodivala-dilke@qmul.ac.uk., D'Amico G; Barts Cancer Institute, Queen Mary University of London, Charterhouse Square, London, UK. g.damico@qmul.ac.uk.

Source: Angiogenesis [Angiogenesis] 2026 Jun 22; Vol. 29 (3). Date of Electronic Publication: 2026 Jun 22.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Springer Country of Publication: Germany NLM ID: 9814575 Publication Model: Electronic Cited Medium: Internet ISSN: 1573-7209 (Electronic) Linking ISSN: 09696970 NLM ISO Abbreviation: Angiogenesis Subsets: MEDLINE

MeSH Terms: Drug Resistance, Neoplasm*/drug effects , Signal Transduction*/drug effects , Neovascularization, Pathologic*/pathology , Neovascularization, Pathologic*/metabolism , Endothelial Cells*/pathology , Endothelial Cells*/metabolism , Breast Neoplasms*/pathology , Breast Neoplasms*/drug therapy , Breast Neoplasms*/metabolism , Breast Neoplasms*/blood supply , Cellular Reprogramming*/drug effects, Doxorubicin/pharmacology ; NF-kappa B/metabolism ; Animals ; Female ; Mice ; Humans ; Metabolic Reprogramming

Microglia Reprogramming in Glioblastoma: Stem Cell-Derived Factors as Emerging Immunomodulators.

Authors: Amiri Z; Section of Pharmacology, Department of Internal Medicine, University of Genova, Viale Benedetto XV, 2, 16132 Genova, Italy., Tremonti BF; Section of Pharmacology, Department of Internal Medicine, University of Genova, Viale Benedetto XV, 2, 16132 Genova, Italy., Corsaro A; Section of Pharmacology, Department of Internal Medicine, University of Genova, Viale Benedetto XV, 2, 16132 Genova, Italy., Pattarozzi A; Section of Pharmacology, Department of Internal Medicine, University of Genova, Viale Benedetto XV, 2, 16132 Genova, Italy., Bajetto A; Section of Pharmacology, Department of Internal Medicine, University of Genova, Viale Benedetto XV, 2, 16132 Genova, Italy., Barbieri F; Section of Pharmacology, Department of Internal Medicine, University of Genova, Viale Benedetto XV, 2, 16132 Genova, Italy.; IRCCS Azienda Ospedaliera Metropolitana, Largo Rosanna Benzi 10, 16132 Genova, Italy., Thellung S; Section of Pharmacology, Department of Internal Medicine, University of Genova, Viale Benedetto XV, 2, 16132 Genova, Italy.; IRCCS Azienda Ospedaliera Metropolitana, Largo Rosanna Benzi 10, 16132 Genova, Italy., Florio T; Section of Pharmacology, Department of Internal Medicine, University of Genova, Viale Benedetto XV, 2, 16132 Genova, Italy.; IRCCS Azienda Ospedaliera Metropolitana, Largo Rosanna Benzi 10, 16132 Genova, Italy.

Source: Cells [Cells] 2026 May 04; Vol. 15 (9). Date of Electronic Publication: 2026 May 04.

Publication Type: Journal Article; Review

Journal Info: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101600052 Publication Model: Electronic Cited Medium: Internet ISSN: 2073-4409 (Electronic) Linking ISSN: 20734409 NLM ISO Abbreviation: Cells Subsets: MEDLINE

MeSH Terms: Glioblastoma*/pathology , Glioblastoma*/immunology , Glioblastoma*/metabolism , Microglia*/metabolism , Microglia*/pathology , Brain Neoplasms*/pathology , Brain Neoplasms*/immunology , Immunologic Factors*/metabolism , Stem Cells*/metabolism , Cellular Reprogramming*, Extracellular Vesicles/metabolism ; Humans ; Animals ; Tumor Microenvironment ; Metabolic Reprogramming

Inositol Hexaphosphate as a Metabolic Rheostat: Reprogramming and Plasticity in Stem Cells and Disease States.

Authors: Lin JY; Department of Audiology and Speech-Language Pathology, Mackay Medical University, 252005 New Taipei City, Taiwan.; Institute of Biomedical Sciences, Mackay Medical University, 252005 New Taipei City, Taiwan.; Institute of Brain Science, National Yang Ming Chiao Tung University, 112304 Taipei City, Taiwan., Yang CCH; Institute of Brain Science, National Yang Ming Chiao Tung University, 112304 Taipei City, Taiwan.; Sleep Research Center, National Yang Ming Chiao Tung University, 112304 Taipei City, Taiwan.; Brain Research Center, National Yang Ming Chiao Tung University, 112304 Taipei City, Taiwan., Hsu YC; Department of Audiology and Speech-Language Pathology, Mackay Medical University, 252005 New Taipei City, Taiwan.; Institute of Biomedical Sciences, Mackay Medical University, 252005 New Taipei City, Taiwan.

Source: Frontiers in bioscience (Landmark edition) [Front Biosci (Landmark Ed)] 2026 May 22; Vol. 31 (5), pp. 49611.

Publication Type: Journal Article; Review

Journal Info: Publisher: IMR Press Country of Publication: Singapore NLM ID: 101612996 Publication Model: Print Cited Medium: Internet ISSN: 2768-6698 (Electronic) Linking ISSN: 27686698 NLM ISO Abbreviation: Front Biosci (Landmark Ed) Subsets: MEDLINE

MeSH Terms: Phytic Acid*/metabolism , Phytic Acid*/pharmacology , Stem Cells*/metabolism , Neoplasms*/metabolism , Neoplasms*/pathology , Cellular Reprogramming*, Mitochondria/metabolism ; Humans ; Metabolic Reprogramming ; Animals ; Signal Transduction ; Glycolysis

MicroRNA-targeted reprogramming of CD8+ T cells against cancer.

Authors: Mao Y; Department of Oncology, The First Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang, Jiangxi, China.; The First Clinical Medical College, Jiangxi Medical College, Nanchang University, Nanchang, Jiangxi, China., Liu Y; The First Clinical Medical College, Jiangxi Medical College, Nanchang University, Nanchang, Jiangxi, China., Jing K; The First Clinical Medical College, Jiangxi Medical College, Nanchang University, Nanchang, Jiangxi, China., Shao Y; The Second Clinical Medical College, Jiangxi Medical College, Nanchang University, Nanchang, Jiangxi, China., Yang K; The Second Clinical Medical College, Jiangxi Medical College, Nanchang University, Nanchang, Jiangxi, China., Wu J; The Second Clinical Medical College, Jiangxi Medical College, Nanchang University, Nanchang, Jiangxi, China., Zhou X; The Second Clinical Medical College, Jiangxi Medical College, Nanchang University, Nanchang, Jiangxi, China., Wang H; Department of Orthopedics, The First Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang, Jiangxi, China., Fang Z; Department of Oncology, The First Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang, Jiangxi, China.

Source: Frontiers in immunology [Front Immunol] 2026 Apr 24; Vol. 17, pp. 1770102. Date of Electronic Publication: 2026 Apr 24 (Print Publication: 2026).

Publication Type: Journal Article; Review

Journal Info: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101560960 Publication Model: eCollection Cited Medium: Internet ISSN: 1664-3224 (Electronic) Linking ISSN: 16643224 NLM ISO Abbreviation: Front Immunol Subsets: MEDLINE

MeSH Terms: MicroRNAs*/genetics , MicroRNAs*/immunology , CD8-Positive T-Lymphocytes*/immunology , CD8-Positive T-Lymphocytes*/metabolism , Neoplasms*/immunology , Neoplasms*/genetics , Neoplasms*/therapy , Cellular Reprogramming*/genetics , Cellular Reprogramming*/immunology, Tumor Microenvironment/immunology ; Tumor Microenvironment/genetics ; Humans ; Animals ; Exosomes ; Gene Expression Regulation, Neoplastic ; Metabolic Reprogramming

NADH reductive stress drives metabolic reprogramming.

Authors: Yang R; Beijing Institute of Hepatology, Beijing Youan Hospital, Capital Medical University, Beijing 100069, China., Guo Z; Beijing Institute of Hepatology, Beijing Youan Hospital, Capital Medical University, Beijing 100069, China., Li B; Beijing Institute of Hepatology, Beijing Youan Hospital, Capital Medical University, Beijing 100069, China. Electronic address: bli@ccmu.edu.cn.

Source: Trends in cell biology [Trends Cell Biol] 2026 Mar; Vol. 36 (3), pp. 177-189. Date of Electronic Publication: 2025 Aug 05.

Publication Type: Journal Article; Review

Journal Info: Publisher: Elsevier Science Publishers Country of Publication: England NLM ID: 9200566 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-3088 (Electronic) Linking ISSN: 09628924 NLM ISO Abbreviation: Trends Cell Biol Subsets: MEDLINE

MeSH Terms: NAD*/metabolism , Cellular Reprogramming*, Humans ; Animals ; Oxidation-Reduction ; Oxidative Stress ; Energy Metabolism ; Signal Transduction ; Metabolic Reprogramming

Reprogramming Induced Pluripotent Stem Cell Lines from Frozen Buffy Coat Samples.

Authors: Art J; Center for Molecular Medicine, University of Georgia; Interdisciplinary Neuroscience, University of Georgia; js.esquibel@yahoo.com., James C; Center for Molecular Medicine, University of Georgia; Department of Biochemistry and Molecular Biology, University of Georgia., Dalal B; Center for Molecular Medicine, University of Georgia; Department of Biochemistry and Molecular Biology, University of Georgia., Fantone K; Department of Infectious Diseases, College of Veterinary Medicine, University of Georgia., Rada B; Department of Infectious Diseases, College of Veterinary Medicine, University of Georgia., Felner EI; Division of Pediatric Endocrinology, Emory University School of Medicine., Gonzalez-Duarte A; Dysautonomia Center, New York University Langone Health., Michopoulos V; Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine., Corneo B; Stem Cell Core, Columbia Stem Cell Initiative, Columbia University., Zeltner N; Center for Molecular Medicine, University of Georgia; Department of Biochemistry and Molecular Biology, University of Georgia; Department of Cellular Biology, University of Georgia.

Source: Journal of visualized experiments : JoVE [J Vis Exp] 2026 Apr 10 (230). Date of Electronic Publication: 2026 Apr 10.

Publication Type: Journal Article; Video-Audio Media; Research Support, N.I.H., Extramural

Journal Info: Publisher: MYJoVE Corporation Country of Publication: United States NLM ID: 101313252 Publication Model: Electronic Cited Medium: Internet ISSN: 1940-087X (Electronic) Linking ISSN: 1940087X NLM ISO Abbreviation: J Vis Exp Subsets: MEDLINE

MeSH Terms: Induced Pluripotent Stem Cells*/cytology , Blood Buffy Coat*/cytology , Cellular Reprogramming Techniques*/methods, Leukocytes, Mononuclear/cytology ; Humans ; Cryopreservation ; Cellular Reprogramming

Reprogramming CAR T cells across genetic, epigenetic, metabolic and microenvironmental axes to improve efficacy and safety in cancer and autoimmune disease.

Authors: Scherlinger M; Rheumatology Department, National Reference Center for Systemic Autoimmune Diseases (CNR RESO), Strasbourg University Hospital, Strasbourg, France.; UMR Inserm 1109 Immuno-Rhumatologie Moléculaire, Centre de recherche en biomédecine de Strasbourg (CRBS), Strasbourg, France.

Source: Frontiers in immunology [Front Immunol] 2026 Apr 07; Vol. 17, pp. 1806459. Date of Electronic Publication: 2026 Apr 07 (Print Publication: 2026).

Publication Type: Journal Article; Review

Journal Info: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101560960 Publication Model: eCollection Cited Medium: Internet ISSN: 1664-3224 (Electronic) Linking ISSN: 16643224 NLM ISO Abbreviation: Front Immunol Subsets: MEDLINE

MeSH Terms: Autoimmune Diseases*/therapy , Autoimmune Diseases*/immunology , Autoimmune Diseases*/genetics , Autoimmune Diseases*/metabolism , Neoplasms*/therapy , Neoplasms*/immunology , Neoplasms*/genetics , Neoplasms*/metabolism , Immunotherapy, Adoptive*/methods , Immunotherapy, Adoptive*/adverse effects , Receptors, Chimeric Antigen*/immunology , Receptors, Chimeric Antigen*/genetics , Receptors, Chimeric Antigen*/metabolism , T-Lymphocytes*/immunology , T-Lymphocytes*/metabolism , Epigenesis, Genetic* , Cellular Reprogramming*, Tumor Microenvironment/immunology ; Humans ; Animals ; Metabolic Reprogramming

Remodeling of Mitochondrial Networks: Cellular Adaptation and Microenvironmental Reprogramming in Hematologic Malignancies.

Authors: Li Y; Department of Hematology, Shandong Provincial Hospital, Cheeloo College of Medicine, Shandong University, Jinan, China., Hu X; Department of Hematology, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, China., Zhou X; Department of Hematology, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, China.; National Clinical Research Center for Hematologic Diseases, the First Affiliated Hospital of Soochow University, Suzhou, China.

Source: Blood cancer discovery [Blood Cancer Discov] 2026 Mar 04; Vol. 7 (2), pp. 212-224.

Publication Type: Journal Article; Review

Journal Info: Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 101764786 Publication Model: Print Cited Medium: Internet ISSN: 2643-3249 (Electronic) Linking ISSN: 26433230 NLM ISO Abbreviation: Blood Cancer Discov Subsets: MEDLINE

MeSH Terms: Hematologic Neoplasms*/metabolism , Hematologic Neoplasms*/pathology , Hematologic Neoplasms*/genetics , Mitochondria*/metabolism , Mitochondria*/pathology , Mitochondria*/genetics , Tumor Microenvironment* , Cellular Reprogramming*, Humans ; Animals ; Metabolic Reprogramming ; Mitophagy

Spatiotemporal dynamics of radioresistance: decoding macrophage-driven radioprotective niches through temporal-spatial reprogramming.

Authors: Zhang M; Department of Radiation Oncology, First Hospital of China Medical University, Shenyang, 110001, People's Republic of China.; Department of Pharmacology, School of Pharmacy, China Medical University, Shenyang, 110122, People's Republic of China., Zhang X; Department of Pharmacology, School of Pharmacy, China Medical University, Shenyang, 110122, People's Republic of China., Song X; Department of Pharmacology, School of Pharmacy, China Medical University, Shenyang, 110122, People's Republic of China., Bai R; Department of Pharmacology, School of Pharmacy, Shengjing Hospital of China Medical University, Shenyang, 110004, People's Republic of China., Qiao Q; Department of Radiation Oncology, First Hospital of China Medical University, Shenyang, 110001, People's Republic of China. braveheart8063@outlook.com., Wei M; Department of Pharmacology, School of Pharmacy, China Medical University, Shenyang, 110122, People's Republic of China. mjwei@cmu.edu.cn.; Liaoning Key Laboratory of Molecular Targeted Anti-Tumor Drug Development and Evaluation, China Medical University, Shenyang, 110122, People's Republic of China. mjwei@cmu.edu.cn., Zhao L; Department of Pharmacology, School of Pharmacy, China Medical University, Shenyang, 110122, People's Republic of China. lzhao@cmu.edu.cn.; Liaoning Key Laboratory of Molecular Targeted Anti-Tumor Drug Development and Evaluation, China Medical University, Shenyang, 110122, People's Republic of China. lzhao@cmu.edu.cn.

Source: Molecular cancer [Mol Cancer] 2026 Mar 03; Vol. 25 (1). Date of Electronic Publication: 2026 Mar 03.

Publication Type: Journal Article; Review

Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101147698 Publication Model: Electronic Cited Medium: Internet ISSN: 1476-4598 (Electronic) Linking ISSN: 14764598 NLM ISO Abbreviation: Mol Cancer Subsets: MEDLINE

MeSH Terms: Tumor Microenvironment*/radiation effects , Tumor Microenvironment*/immunology , Tumor-Associated Macrophages*/metabolism , Tumor-Associated Macrophages*/immunology , Tumor-Associated Macrophages*/radiation effects , Neoplasms*/radiotherapy , Neoplasms*/pathology , Neoplasms*/metabolism , Neoplasms*/immunology , Macrophages*/metabolism , Macrophages*/immunology , Radiation Tolerance* , Cellular Reprogramming*, Humans ; Animals ; Metabolic Reprogramming

Deciphering reprogramming efficiency in human induced pluripotent stem cells: insights from the generation of 150 cell lines.

Authors: Kuebler B; Barcelona Stem Cell Bank, Regenerative Medicine Program, Institut d'Investigació Biomèdica de Bellvitge (IDIBELL), L´Hospitalet de Llobregat, Spain.; Program for Clinical Translation of Regenerative Medicine in Catalonia (P-[CMRC]), L´Hospitalet de Llobregat, Spain., Selvitella S; Barcelona Stem Cell Bank, Regenerative Medicine Program, Institut d'Investigació Biomèdica de Bellvitge (IDIBELL), L´Hospitalet de Llobregat, Spain.; Program for Clinical Translation of Regenerative Medicine in Catalonia (P-[CMRC]), L´Hospitalet de Llobregat, Spain., Aran B; Barcelona Stem Cell Bank, Regenerative Medicine Program, Institut d'Investigació Biomèdica de Bellvitge (IDIBELL), L´Hospitalet de Llobregat, Spain.; Program for Clinical Translation of Regenerative Medicine in Catalonia (P-[CMRC]), L´Hospitalet de Llobregat, Spain., Raya A; Program for Clinical Translation of Regenerative Medicine in Catalonia (P-[CMRC]), L´Hospitalet de Llobregat, Spain.; Stem Cell Potency Group, Regenerative Medicine Program, Institut d'Investigació Biomèdica de Bellvitge (IDIBELL), L´Hospitalet de Llobregat, Spain.; Center for Networked Biomedical Research on Bioengineering, Biomaterials and Nanomedicine (CIBER-BBN), Madrid, Spain.; Physiological Sciences Department, Faculty of Medicine and Health Sciences, University of Barcelona, L´Hospitalet de Llobregat, Spain.; Institució Catalana de Recerca i Estudis Avançats (ICREA), Barcelona, Spain., Veiga A; Barcelona Stem Cell Bank, Regenerative Medicine Program, Institut d'Investigació Biomèdica de Bellvitge (IDIBELL), L´Hospitalet de Llobregat, Spain.; Program for Clinical Translation of Regenerative Medicine in Catalonia (P-[CMRC]), L´Hospitalet de Llobregat, Spain.

Source: Frontiers in immunology [Front Immunol] 2026 Jan 13; Vol. 16, pp. 1719056. Date of Electronic Publication: 2026 Jan 13 (Print Publication: 2025).

Publication Type: Journal Article

Journal Info: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101560960 Publication Model: eCollection Cited Medium: Internet ISSN: 1664-3224 (Electronic) Linking ISSN: 16643224 NLM ISO Abbreviation: Front Immunol Subsets: MEDLINE

MeSH Terms: Induced Pluripotent Stem Cells*/cytology , Induced Pluripotent Stem Cells*/metabolism , Induced Pluripotent Stem Cells*/physiology , Cellular Reprogramming*/genetics, Humans ; Cell Line ; Cell Differentiation ; Cellular Reprogramming Techniques

The role of m6A reader IGF2BPs in tumor metabolic reprogramming.

Authors: Zhou X; The Affiliated Nanhua Hospital, Department of Clinical Laboratory, Hengyang Medical School, University of South China, Hengyang, Hunan 421001, China., Li G; Institute of Cardiovascular Disease, Key Laboratory for Arteriosclerology of Hunan Province, Hunan International Scientific and Technological Cooperation Base of Arteriosclerotic Disease, Department of Pathophysiology, School of Basic Medical Sciences, Hengyang Medical School, University of South China, Hengyang, Hunan 421001, China., Su X; The Affiliated Nanhua Hospital, Department of Clinical Laboratory, Hengyang Medical School, University of South China, Hengyang, Hunan 421001, China., Wang Y; The Affiliated Nanhua Hospital, Department of Clinical Laboratory, Hengyang Medical School, University of South China, Hengyang, Hunan 421001, China., Liu L; Hunan Province Key Laboratory of Basic and Applied Hematology, Molecular Biology Research Center & Center for Medical Genetics, School of Life Sciences, Central South University, Changsha 410078 Hunan, China., Yang C; Hunan Province Key Laboratory of Basic and Applied Hematology, Molecular Biology Research Center & Center for Medical Genetics, School of Life Sciences, Central South University, Changsha 410078 Hunan, China., Xu Y; The Affiliated Nanhua Hospital, Department of Clinical Laboratory, Hengyang Medical School, University of South China, Hengyang, Hunan 421001, China., He J; The Affiliated Nanhua Hospital, Department of Hepatobiliary Surgery, Hengyang Medical School, University of South China, Hengyang, Hunan 421001, China. Electronic address: 1684131533@qq.com., Zhang J; The Affiliated Nanhua Hospital, Department of Clinical Laboratory, Hengyang Medical School, University of South China, Hengyang, Hunan 421001, China. Electronic address: zhang_ji001@hotmail.com.

Source: Biochemical pharmacology [Biochem Pharmacol] 2026 Jan; Vol. 243 (Pt 1), pp. 117452. Date of Electronic Publication: 2025 Oct 24.

Publication Type: Journal Article; Review; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Elsevier Science Country of Publication: England NLM ID: 0101032 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-2968 (Electronic) Linking ISSN: 00062952 NLM ISO Abbreviation: Biochem Pharmacol Subsets: MEDLINE

MeSH Terms: Neoplasms*/metabolism , Neoplasms*/genetics , RNA-Binding Proteins*/metabolism , RNA-Binding Proteins*/genetics , Adenosine*/analogs & derivatives , Adenosine*/metabolism , Cellular Reprogramming*/physiology, Lipid Metabolism/physiology ; Glycolysis/physiology ; Insulin-Like Growth Factor II/metabolism ; Humans ; Animals ; Metabolic Reprogramming

Metabolic reprogramming of pancreatic beta cells in type 2 diabetes and its therapeutic strategy.

Authors: Miao L; Chengdu University of Traditional Chinese Medicine, Chengdu 610075, China; Institute of Metabolic Diseases, Guang'anmen Hospital, China Academy of Chinese Medical Sciences, Beijing, China. Electronic address: 1249448953@qq.com., Miao R; Oncology Department of Integrative Medicine, China-Japan Friendship Hospital, Beijing, China. Electronic address: 20160141002@bucm.edu.cn., Yao Y; Institute of Metabolic Diseases, Guang'anmen Hospital, China Academy of Chinese Medical Sciences, Beijing, China. Electronic address: gzucm2019@126.com., Fang X; Institute of Metabolic Diseases, Guang'anmen Hospital, China Academy of Chinese Medical Sciences, Beijing, China; Graduate College, Beijing University of Chinese Medicine, Beijing, China. Electronic address: 749860324@qq.com., Guan H; Institute of Metabolic Diseases, Guang'anmen Hospital, China Academy of Chinese Medical Sciences, Beijing, China; Changchun University of Chinese Medicine, Changchun, China. Electronic address: 20202701028@stu.ccucm.edu.cn., Tian J; Institute of Metabolic Diseases, Guang'anmen Hospital, China Academy of Chinese Medical Sciences, Beijing, China. Electronic address: tina_yai@126.com., Tong X; Institute of Metabolic Diseases, Guang'anmen Hospital, China Academy of Chinese Medical Sciences, Beijing, China. Electronic address: tongxiaolin@vip.163.com.

Source: Ageing research reviews [Ageing Res Rev] 2026 Jan; Vol. 113, pp. 102938. Date of Electronic Publication: 2025 Nov 12.

Publication Type: Journal Article; Review

Journal Info: Publisher: Elsevier Science Country of Publication: England NLM ID: 101128963 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1872-9649 (Electronic) Linking ISSN: 15681637 NLM ISO Abbreviation: Ageing Res Rev Subsets: MEDLINE

MeSH Terms: Diabetes Mellitus, Type 2*/metabolism , Diabetes Mellitus, Type 2*/therapy , Diabetes Mellitus, Type 2*/pathology , Insulin-Secreting Cells*/metabolism , Insulin-Secreting Cells*/pathology , Cellular Reprogramming*/physiology, Humans ; Animals ; Metabolic Reprogramming

Metabolic reprogramming and immune regulation in acute myeloid leukemia.

Authors: Hao X; First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, National Clinical Research Center for Chinese Medicine Acupuncture and Moxibustion, Tianjin, China., Fan C; First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, National Clinical Research Center for Chinese Medicine Acupuncture and Moxibustion, Tianjin, China., Yan L; First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, National Clinical Research Center for Chinese Medicine Acupuncture and Moxibustion, Tianjin, China., Jianati R; First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, National Clinical Research Center for Chinese Medicine Acupuncture and Moxibustion, Tianjin, China., Guo Y; First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, National Clinical Research Center for Chinese Medicine Acupuncture and Moxibustion, Tianjin, China., Zhou X; First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, National Clinical Research Center for Chinese Medicine Acupuncture and Moxibustion, Tianjin, China., Zhu G; First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, National Clinical Research Center for Chinese Medicine Acupuncture and Moxibustion, Tianjin, China., Zhang Y; First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, National Clinical Research Center for Chinese Medicine Acupuncture and Moxibustion, Tianjin, China., Zheng C; First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, National Clinical Research Center for Chinese Medicine Acupuncture and Moxibustion, Tianjin, China., Zhang Y; First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, National Clinical Research Center for Chinese Medicine Acupuncture and Moxibustion, Tianjin, China., Shi Z; First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, National Clinical Research Center for Chinese Medicine Acupuncture and Moxibustion, Tianjin, China.

Source: Frontiers in immunology [Front Immunol] 2025 Dec 10; Vol. 16, pp. 1655005. Date of Electronic Publication: 2025 Dec 10 (Print Publication: 2025).

Publication Type: Journal Article; Review

Journal Info: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101560960 Publication Model: eCollection Cited Medium: Internet ISSN: 1664-3224 (Electronic) Linking ISSN: 16643224 NLM ISO Abbreviation: Front Immunol Subsets: MEDLINE

MeSH Terms: Leukemia, Myeloid, Acute*/metabolism , Leukemia, Myeloid, Acute*/immunology , Leukemia, Myeloid, Acute*/therapy , Energy Metabolism* , Cellular Reprogramming* , Immunomodulation*, Tumor Microenvironment/immunology ; Immunotherapy/methods ; Metabolic Networks and Pathways/immunology ; Humans ; Animals ; Metabolic Reprogramming

AMPK maintains the activation of hepatic stellate cells through mitophagy-induced metabolic reprogramming.

Authors: Wang H; State Key Laboratory of Chemical Biology, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China.; Shandong Laboratory of Yantai Drug Discovery, Bohai Rim Advanced Research Institute for Drug Discovery, Yantai 264117, China.; University of Chinese Academy of Sciences, Beijing 100049, China., Wang G; State Key Laboratory of Chemical Biology, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China.; University of Chinese Academy of Sciences, Beijing 100049, China., Yin T; State Key Laboratory of Chemical Biology, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China.; University of Chinese Academy of Sciences, Beijing 100049, China.; Lingang Laboratory, Shanghai 200031, China., Li H; School of Chinese Materia Medica, Nanjing University of Chinese Medicine, Nanjing 210023, China., Wang H; State Key Laboratory of Chemical Biology, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China.; University of Chinese Academy of Sciences, Beijing 100049, China., Shao Y; Center for Obesity and Hernia Surgery, Huashan Hospital of Fudan University, Shanghai 200040, China.; Department of General Surgery, Huashan Hospital of Fudan University, Shanghai 200040, China.; National Center for Neurological Disorders, Huashan Hospital of Fudan University, Shanghai 200040, China., Li Y; State Key Laboratory of Chemical Biology, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China.; University of Chinese Academy of Sciences, Beijing 100049, China.; Zhongshan Institute for Drug Discovery, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Zhongshan 528400, China., Hua R; Center for Obesity and Hernia Surgery, Huashan Hospital of Fudan University, Shanghai 200040, China.; Department of General Surgery, Huashan Hospital of Fudan University, Shanghai 200040, China.; National Center for Neurological Disorders, Huashan Hospital of Fudan University, Shanghai 200040, China., Li J; State Key Laboratory of Chemical Biology, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China.; Shandong Laboratory of Yantai Drug Discovery, Bohai Rim Advanced Research Institute for Drug Discovery, Yantai 264117, China.; University of Chinese Academy of Sciences, Beijing 100049, China.; Zhongshan Institute for Drug Discovery, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Zhongshan 528400, China.; School of Pharmaceutical Science and Technology, Hangzhou Institute for Advanced Study, University of Chinese Academy of Sciences, Hangzhou 310024, China., Zang Y; Lingang Laboratory, Shanghai 200031, China.

Source: Journal of molecular cell biology [J Mol Cell Biol] 2026 Feb 13; Vol. 17 (7).

Publication Type: Journal Article

Journal Info: Publisher: Oxford University Press Country of Publication: United States NLM ID: 101503669 Publication Model: Print Cited Medium: Internet ISSN: 1759-4685 (Electronic) Linking ISSN: 17594685 NLM ISO Abbreviation: J Mol Cell Biol Subsets: MEDLINE

MeSH Terms: Hepatic Stellate Cells*/metabolism , Hepatic Stellate Cells*/pathology , AMP-Activated Protein Kinases*/metabolism , AMP-Activated Protein Kinases*/genetics , Mitophagy* , Cellular Reprogramming*, Liver Cirrhosis/pathology ; Liver Cirrhosis/metabolism ; Mitochondria/metabolism ; Animals ; Mice ; Humans ; Mice, Inbred C57BL ; Male ; Carbon Tetrachloride ; Signal Transduction ; Phosphorylation ; Metabolic Reprogramming

Integrative methylation and transcriptomic analysis reveals key genes linking cellular senescence and metabolic reprogramming in colorectal liver metastasis.

Authors: Ma X; Department of General Surgery, Hepatobiliary Surgery Center, Huashan Hospital & Cancer Metastasis Institute, Fudan University, Shanghai, China., Chen L; Department of Hepatobiliary Cancer, Liver cancer research center, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Tianjin Key Laboratory of Digestive Cancer, Tianjin's Clinical Research Center for Cancer, Tianjin, China., Yi C; Department of General Surgery, Hepatobiliary Surgery Center, Huashan Hospital & Cancer Metastasis Institute, Fudan University, Shanghai, China., Li Y; Department of General Surgery, Hepatobiliary Surgery Center, Huashan Hospital & Cancer Metastasis Institute, Fudan University, Shanghai, China., Geng Y; Department of General Surgery, Hepatobiliary Surgery Center, Huashan Hospital & Cancer Metastasis Institute, Fudan University, Shanghai, China., Tao B; Department of General Surgery, Hepatobiliary Surgery Center, Huashan Hospital & Cancer Metastasis Institute, Fudan University, Shanghai, China., Chen J; Department of General Surgery, Hepatobiliary Surgery Center, Huashan Hospital & Cancer Metastasis Institute, Fudan University, Shanghai, China.

Source: Bioscience trends [Biosci Trends] 2026 Jan 07; Vol. 19 (6), pp. 672-683. Date of Electronic Publication: 2025 Oct 31.

Publication Type: Journal Article

Journal Info: Publisher: International Research and Cooperation Association for Bio & Socio-Sciences Advancement Country of Publication: Japan NLM ID: 101502754 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1881-7823 (Electronic) Linking ISSN: 18817815 NLM ISO Abbreviation: Biosci Trends Subsets: MEDLINE

MeSH Terms: Liver Neoplasms*/secondary , Liver Neoplasms*/genetics , Liver Neoplasms*/metabolism , Colorectal Neoplasms*/genetics , Colorectal Neoplasms*/pathology , Colorectal Neoplasms*/metabolism , DNA Methylation*/genetics , Cellular Senescence*/genetics , Cellular Reprogramming*/genetics, Chemokine CXCL1/genetics ; Plasminogen Activator Inhibitor 1/genetics ; Intracellular Signaling Peptides and Proteins/genetics ; Fluorouracil/pharmacology ; Fluorouracil/therapeutic use ; Biomarkers, Tumor/genetics ; Oxaliplatin/pharmacology ; Oxaliplatin/therapeutic use ; Humans ; Gene Expression Profiling ; Gene Expression Regulation, Neoplastic ; Transcriptome ; Epigenesis, Genetic ; Metabolic Reprogramming ; Cell Cycle Proteins ; N-myc Downstream-Regulated Gene 1 Protein

Trained immunity attenuated acute lung injury by activating alveolar macrophages via AKT2-PDK1 axis-mediated metabolic reprogramming.

Authors: Sun Z; College of Life Science, Institute of Biomedical Science, Henan Normal University, Xinxiang, Henan, China.; State Key Laboratory of Cell Differentiation and Regulation, Xinxiang, Henan, China., Meng H; College of Life Science, Institute of Biomedical Science, Henan Normal University, Xinxiang, Henan, China.; State Key Laboratory of Cell Differentiation and Regulation, Xinxiang, Henan, China., Wang X; College of Life Science, Institute of Biomedical Science, Henan Normal University, Xinxiang, Henan, China.; State Key Laboratory of Cell Differentiation and Regulation, Xinxiang, Henan, China., Guo X; College of Life Science, Institute of Biomedical Science, Henan Normal University, Xinxiang, Henan, China.; State Key Laboratory of Cell Differentiation and Regulation, Xinxiang, Henan, China., He W; College of Life Science, Institute of Biomedical Science, Henan Normal University, Xinxiang, Henan, China.; State Key Laboratory of Cell Differentiation and Regulation, Xinxiang, Henan, China., Zhou Y; College of Life Science, Institute of Biomedical Science, Henan Normal University, Xinxiang, Henan, China.; State Key Laboratory of Cell Differentiation and Regulation, Xinxiang, Henan, China., Wang Z; College of Life Science, Institute of Biomedical Science, Henan Normal University, Xinxiang, Henan, China.; State Key Laboratory of Cell Differentiation and Regulation, Xinxiang, Henan, China., Li Z; Department of Pulmonary and Critical Care Medicine, Hebei Chest Hospital, Shijiazhuang, Hebei, China. li-zhsh@163.com.; Hebei Provincial Key Laboratory of Pulmonary Disease, Shijiazhuang, Hebei, China. li-zhsh@163.com., Li X; Department of Pulmonary and Critical Care Medicine, Hebei Chest Hospital, Shijiazhuang, Hebei, China. lixingbin@126.com.; Hebei Provincial Key Laboratory of Pulmonary Disease, Shijiazhuang, Hebei, China. lixingbin@126.com., Wang Y; Department of Pulmonary and Critical Care Medicine, Hebei Chest Hospital, Shijiazhuang, Hebei, China. yuanwang3389@163.com.; Hebei Provincial Key Laboratory of Pulmonary Disease, Shijiazhuang, Hebei, China. yuanwang3389@163.com.

Source: Journal of translational medicine [J Transl Med] 2025 Dec 23; Vol. 23 (1), pp. 1412. Date of Electronic Publication: 2025 Dec 23.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101190741 Publication Model: Electronic Cited Medium: Internet ISSN: 1479-5876 (Electronic) Linking ISSN: 14795876 NLM ISO Abbreviation: J Transl Med Subsets: MEDLINE

MeSH Terms: Macrophages, Alveolar*/metabolism , Macrophages, Alveolar*/immunology , Macrophages, Alveolar*/drug effects , Acute Lung Injury*/immunology , Acute Lung Injury*/pathology , Acute Lung Injury*/metabolism , Proto-Oncogene Proteins c-akt*/metabolism , Cellular Reprogramming*, Lipopolysaccharides/pharmacology ; Signal Transduction/drug effects ; beta-Glucans/pharmacology ; Glycolysis/drug effects ; Pyruvate Dehydrogenase Acetyl-Transferring Kinase/metabolism ; Lactic Acid/metabolism ; Animals ; Male ; Mice, Inbred C57BL ; Mice ; Metabolic Reprogramming ; Trained Immunity