LC/MS guided discovery of new kavalactone derivatives in the pericarps of Alpinia zerumbet.

Συγγραφείς: Nishidono Y; Pharmaceutical Research and Technology Institute, Kindai University, Higashi-osaka, Osaka 577-8502, Japan; College of Pharmaceutical Sciences, Ritsumeikan University, Kusatsu, Shiga 525-8577, Japan. Electronic address: nisidono@phar.kindai.ac.jp., Okuyama T; Department of Pancreatobiliary Surgery, Kansai Medical University, Hirakata, Osaka 573-1010, Japan., Nakatake R; Department of Pancreatobiliary Surgery, Kansai Medical University, Hirakata, Osaka 573-1010, Japan., Tanaka K; College of Pharmaceutical Sciences, Ritsumeikan University, Kusatsu, Shiga 525-8577, Japan., Morikawa T; Pharmaceutical Research and Technology Institute, Kindai University, Higashi-osaka, Osaka 577-8502, Japan; Antiaging Center, Kindai University, Higashi-osaka, Osaka 577-8502, Japan.

Πηγή: Fitoterapia [Fitoterapia] 2026 Oct; Vol. 194, pp. 107450. Date of Electronic Publication: 2026 Sep 04.

Τύπος έκδοσης: Journal Article

Στοιχεία περιοδικού: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 16930290R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-6971 (Electronic) Linking ISSN: 0367326X NLM ISO Abbreviation: Fitoterapia Subsets: MEDLINE

Ιατρικοί όροι (MeSH): Alpinia*/chemistry , Pyrones*/chemistry , Pyrones*/isolation & purification , Lactones*/chemistry , Lactones*/isolation & purification, Fruit/chemistry ; Chromatography, Liquid/methods ; Monoterpenes/chemistry ; Monoterpenes/isolation & purification ; Plant Extracts/chemistry ; Magnetic Resonance Spectroscopy ; Mass Spectrometry

A trimethyl lock successfully stabilizes a nascent Michael acceptor for prodrug applications.

Συγγραφείς: Cheema EK; Department of Chemistry, Johns Hopkins University, Baltimore, MD 21218, USA. rokita@jhu.edu., Rokita SE; Department of Chemistry, Johns Hopkins University, Baltimore, MD 21218, USA. rokita@jhu.edu.

Πηγή: Chemical communications (Cambridge, England) [Chem Commun (Camb)] 2026 Oct 15; Vol. 62 (81), pp. 20326-20329. Date of Electronic Publication: 2026 Oct 15.

Τύπος έκδοσης: Journal Article

Στοιχεία περιοδικού: Publisher: Royal Society of Chemistry Country of Publication: England NLM ID: 9610838 Publication Model: Electronic Cited Medium: Internet ISSN: 1364-548X (Electronic) Linking ISSN: 13597345 NLM ISO Abbreviation: Chem Commun (Camb) Subsets: MEDLINE

Ιατρικοί όροι (MeSH): Prodrugs*/chemistry , Prodrugs*/pharmacology , Prodrugs*/metabolism , STAT3 Transcription Factor*/antagonists & inhibitors , STAT3 Transcription Factor*/metabolism , Pyrones*/chemistry , Pyrones*/pharmacology, NAD(P)H Dehydrogenase (Quinone)/metabolism ; Humans

Tyrosinase inhibition mechanism of kojic acid-phenylpiperazine derivatives and their anti-browning effect on fresh-cut apples.

Συγγραφείς: Zhao Y; State Key Laboratory of Discovery and Utilization of Functional Components in Traditional Chinese Medicine, Engineering Research Center for the Development and Application of Ethnic Medicine and TCM (Ministry of Education), Guizhou Provincial Engineering Research Center for the Development and Application of Ethnic Medicine and TCM, Guizhou Medical University, Guian New Area, 561113, China; School of Pharmaceutical Sciences, Guizhou Medical University, Guian New Area, 561113, China., Zhang J; State Key Laboratory of Discovery and Utilization of Functional Components in Traditional Chinese Medicine, Engineering Research Center for the Development and Application of Ethnic Medicine and TCM (Ministry of Education), Guizhou Provincial Engineering Research Center for the Development and Application of Ethnic Medicine and TCM, Guizhou Medical University, Guian New Area, 561113, China; School of Pharmaceutical Sciences, Guizhou Medical University, Guian New Area, 561113, China., Huang Y; State Key Laboratory of Discovery and Utilization of Functional Components in Traditional Chinese Medicine, Engineering Research Center for the Development and Application of Ethnic Medicine and TCM (Ministry of Education), Guizhou Provincial Engineering Research Center for the Development and Application of Ethnic Medicine and TCM, Guizhou Medical University, Guian New Area, 561113, China; School of Pharmaceutical Sciences, Guizhou Medical University, Guian New Area, 561113, China., Peng Z; Clinical Trails Center, The Affiliated Hospital of Guizhou Medical University, Guiyang 550004, China. Electronic address: pengzhiyun1986@163.com., Wang G; State Key Laboratory of Discovery and Utilization of Functional Components in Traditional Chinese Medicine, Engineering Research Center for the Development and Application of Ethnic Medicine and TCM (Ministry of Education), Guizhou Provincial Engineering Research Center for the Development and Application of Ethnic Medicine and TCM, Guizhou Medical University, Guian New Area, 561113, China. Electronic address: wanggch123@163.com.

Πηγή: Food chemistry [Food Chem] 2026 Oct 01; Vol. 525 (Pt 2), pp. 150421. Date of Electronic Publication: 2026 Jul 14.

Τύπος έκδοσης: Journal Article

Στοιχεία περιοδικού: Publisher: Elsevier Applied Science Publishers Country of Publication: England NLM ID: 7702639 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-7072 (Electronic) Linking ISSN: 03088146 NLM ISO Abbreviation: Food Chem Subsets: MEDLINE

Ιατρικοί όροι (MeSH): Monophenol Monooxygenase*/antagonists & inhibitors , Monophenol Monooxygenase*/chemistry , Enzyme Inhibitors*/chemistry , Enzyme Inhibitors*/pharmacology , Piperazines*/chemistry , Piperazines*/pharmacology , Pyrones*/chemistry , Pyrones*/pharmacology , Malus*/chemistry , Malus*/enzymology , Fungal Proteins*/chemistry , Fungal Proteins*/antagonists & inhibitors , Plant Proteins*/chemistry , Plant Proteins*/antagonists & inhibitors, Fruit/chemistry ; Fruit/enzymology ; Maillard Reaction/drug effects ; Food Preservation/methods ; Humans ; Animals ; Mice ; Kinetics ; Molecular Docking Simulation ; Molecular Structure

Discovery of new α-pyrone derivative with α-glucosidase inhibitory activity from the fungus Acremonium persicinum.

Συγγραφείς: Tu Y; State Key Laboratory of Microbial Diversity and Innovative Utilization, Institute of Microbiology, Chinese Academy of Sciences, Beijing, PR China., Zhang B; State Key Laboratory of Microbial Diversity and Innovative Utilization, Institute of Microbiology, Chinese Academy of Sciences, Beijing, PR China.; University of Chinese Academy of Sciences, Beijing, PR China., Bao M; State Key Laboratory of Microbial Diversity and Innovative Utilization, Institute of Microbiology, Chinese Academy of Sciences, Beijing, PR China.; University of Chinese Academy of Sciences, Beijing, PR China., Ji M; State Key Laboratory of Microbial Diversity and Innovative Utilization, Institute of Microbiology, Chinese Academy of Sciences, Beijing, PR China.; University of Chinese Academy of Sciences, Beijing, PR China., Liu L; State Key Laboratory of Microbial Diversity and Innovative Utilization, Institute of Microbiology, Chinese Academy of Sciences, Beijing, PR China. liul@im.ac.cn.; University of Chinese Academy of Sciences, Beijing, PR China. liul@im.ac.cn.

Πηγή: The Journal of antibiotics [J Antibiot (Tokyo)] 2026 Oct; Vol. 79 (10), pp. 621-625. Date of Electronic Publication: 2026 Jul 15.

Τύπος έκδοσης: Journal Article

Στοιχεία περιοδικού: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 0151115 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1881-1469 (Electronic) Linking ISSN: 00218820 NLM ISO Abbreviation: J Antibiot (Tokyo) Subsets: MEDLINE

Ιατρικοί όροι (MeSH): Acremonium*/chemistry , Acremonium*/metabolism , Glycoside Hydrolase Inhibitors*/pharmacology , Glycoside Hydrolase Inhibitors*/chemistry , Glycoside Hydrolase Inhibitors*/isolation & purification , Pyrones*/pharmacology , Pyrones*/chemistry , Pyrones*/isolation & purification, alpha-Glucosidases/metabolism ; Magnetic Resonance Spectroscopy ; Spectrometry, Mass, Electrospray Ionization ; Molecular Docking Simulation ; Molecular Structure ; Kinetics

Galactosylated Solid Lipid Nanoparticles with Swertiamarin Alleviate Cholestiatic Liver Injury via Enhancing the SIRT1/Nrf2 Pathway.

Συγγραφείς: Wu J; Department of Medicine, City University of Wuhan, Wuhan, 430083, China., Wu T; Department of Hematology, The Sixth Hospital of Wuhan (Affiliated Hospital of Jianghan University), Jianghan University, Wuhan, 430014, China., Guan X; Central Laboratory, Hubei Key Laboratory of Sports Injury and Precision Therapy, Wuhan Fourth Hospital, Hanzheng street 473, Wuhan, 430000, China., Zhu X; Central Laboratory, Hubei Key Laboratory of Sports Injury and Precision Therapy, Wuhan Fourth Hospital, Hanzheng street 473, Wuhan, 430000, China., Lei L; Central Laboratory, Hubei Key Laboratory of Sports Injury and Precision Therapy, Wuhan Fourth Hospital, Hanzheng street 473, Wuhan, 430000, China., Wu T; Central Laboratory, Hubei Key Laboratory of Sports Injury and Precision Therapy, Wuhan Fourth Hospital, Hanzheng street 473, Wuhan, 430000, China. D201178413@alumni.hust.edu.cn., Zhang Q; Department of Pharmacy, General Hospital of the Yangtze River Shipping, Wuhan Brain Hospital, Wuhan, 430014, China.

Πηγή: Applied biochemistry and biotechnology [Appl Biochem Biotechnol] 2026 Oct; Vol. 198 (10), pp. 7410-7427. Date of Electronic Publication: 2026 Jun 13.

Τύπος έκδοσης: Journal Article

Στοιχεία περιοδικού: Publisher: Humana Press Country of Publication: United States NLM ID: 8208561 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1559-0291 (Electronic) Linking ISSN: 02732289 NLM ISO Abbreviation: Appl Biochem Biotechnol Subsets: MEDLINE

Ιατρικοί όροι (MeSH): Sirtuin 1*/metabolism , Nanoparticles*/chemistry , NF-E2-Related Factor 2*/metabolism , Iridoid Glucosides*/pharmacology , Iridoid Glucosides*/chemistry , Pyrones*/pharmacology , Pyrones*/chemistry , Signal Transduction*/drug effects , Galactose*/chemistry , Lipids*/chemistry , Cholestasis*/drug therapy , Cholestasis*/metabolism , Cholestasis*/pathology , Chemical and Drug Induced Liver Injury*/metabolism , Chemical and Drug Induced Liver Injury*/drug therapy , Chemical and Drug Induced Liver Injury*/pathology, Oxidative Stress/drug effects ; Apoptosis/drug effects ; Animals ; Humans ; Mice ; Hep G2 Cells ; Male ; Liposomes

Structural diversity, natural occurrence, synthesis, and bioactivities of naphthopyrones.

Συγγραφείς: Cong M; Guangdong Key Laboratory of Marine Materia Medica, State Key Laboratory of Tropical Oceanography, South China Sea Institute of Oceanology, Chinese Academy of Sciences, Guangzhou, 510301, China; University of Chinese Academy of Sciences, 19 Yuquan Road, Beijing, 100049, China., Shen S; Guangdong Key Laboratory of Marine Materia Medica, State Key Laboratory of Tropical Oceanography, South China Sea Institute of Oceanology, Chinese Academy of Sciences, Guangzhou, 510301, China., Pang X; Guangdong Key Laboratory of Marine Materia Medica, State Key Laboratory of Tropical Oceanography, South China Sea Institute of Oceanology, Chinese Academy of Sciences, Guangzhou, 510301, China; Sanya Institute of Ocean Eco-Environmental Engineering, Sanya, 572000, China., Liu Y; Guangdong Key Laboratory of Marine Materia Medica, State Key Laboratory of Tropical Oceanography, South China Sea Institute of Oceanology, Chinese Academy of Sciences, Guangzhou, 510301, China; University of Chinese Academy of Sciences, 19 Yuquan Road, Beijing, 100049, China; Sanya Institute of Ocean Eco-Environmental Engineering, Sanya, 572000, China. Electronic address: yonghongliu@scsio.ac.cn., Wang J; Guangdong Key Laboratory of Marine Materia Medica, State Key Laboratory of Tropical Oceanography, South China Sea Institute of Oceanology, Chinese Academy of Sciences, Guangzhou, 510301, China; University of Chinese Academy of Sciences, 19 Yuquan Road, Beijing, 100049, China; Sanya Institute of Ocean Eco-Environmental Engineering, Sanya, 572000, China. Electronic address: wangjunfeng@scsio.ac.cn.

Πηγή: Phytochemistry [Phytochemistry] 2026 Oct; Vol. 250, pp. 114985. Date of Electronic Publication: 2026 May 30.

Τύπος έκδοσης: Journal Article; Review

Στοιχεία περιοδικού: Publisher: Elsevier Country of Publication: England NLM ID: 0151434 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-3700 (Electronic) Linking ISSN: 00319422 NLM ISO Abbreviation: Phytochemistry Subsets: MEDLINE

Ιατρικοί όροι (MeSH): Naphthalenes*/chemistry , Naphthalenes*/pharmacology , Naphthalenes*/chemical synthesis , Biological Products*/chemistry , Biological Products*/pharmacology , Biological Products*/chemical synthesis , Pyrones*/chemistry , Pyrones*/pharmacology , Pyrones*/chemical synthesis, Molecular Structure ; Humans ; Animals

Synthesis and biological evaluation of novel Kojic acid-cinnamic acid hybrids as tyrosinase inhibitors.

Συγγραφείς: Wen Y; School of Pharmacy and Food Engineering & Guangdong Provincial Key Laboratory of Large Animal Models for Biomedicine & International Healthcare Innovation Institute (Jiangmen), Wuyi University, Jiangmen, 529020, China., Yu Q; School of Pharmacy and Food Engineering & Guangdong Provincial Key Laboratory of Large Animal Models for Biomedicine & International Healthcare Innovation Institute (Jiangmen), Wuyi University, Jiangmen, 529020, China., Yang F; Jiangmen Customs Technology Center, Jiangmen, 529020, China., Li J; School of Pharmacy and Food Engineering & Guangdong Provincial Key Laboratory of Large Animal Models for Biomedicine & International Healthcare Innovation Institute (Jiangmen), Wuyi University, Jiangmen, 529020, China., Lang M; School of Pharmacy and Food Engineering & Guangdong Provincial Key Laboratory of Large Animal Models for Biomedicine & International Healthcare Innovation Institute (Jiangmen), Wuyi University, Jiangmen, 529020, China. langm2019@163.com., Yan JL; School of Pharmacy and Food Engineering & Guangdong Provincial Key Laboratory of Large Animal Models for Biomedicine & International Healthcare Innovation Institute (Jiangmen), Wuyi University, Jiangmen, 529020, China. yanjialei@wyu.edu.cn., Xu X; School of Pharmacy and Food Engineering & Guangdong Provincial Key Laboratory of Large Animal Models for Biomedicine & International Healthcare Innovation Institute (Jiangmen), Wuyi University, Jiangmen, 529020, China. wyuchemxxt@126.com.

Πηγή: Molecular diversity [Mol Divers] 2026 Oct; Vol. 30 (5), pp. 7235-7246. Date of Electronic Publication: 2026 Mar 01.

Τύπος έκδοσης: Journal Article

Στοιχεία περιοδικού: Publisher: ESCOM Science Publishers Country of Publication: Netherlands NLM ID: 9516534 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1573-501X (Electronic) Linking ISSN: 13811991 NLM ISO Abbreviation: Mol Divers Subsets: MEDLINE

Ιατρικοί όροι (MeSH): Pyrones*/chemistry , Pyrones*/pharmacology , Pyrones*/chemical synthesis , Monophenol Monooxygenase*/antagonists & inhibitors , Monophenol Monooxygenase*/chemistry , Monophenol Monooxygenase*/metabolism , Cinnamates*/chemistry , Cinnamates*/pharmacology , Cinnamates*/chemical synthesis , Enzyme Inhibitors*/pharmacology , Enzyme Inhibitors*/chemical synthesis , Enzyme Inhibitors*/chemistry, Melanins/biosynthesis ; Molecular Docking Simulation ; Animals ; Mice

Drimane-Pyrone-Type Meroterpenoids and Co-Isolated Compounds from the Deep-Sea Fungus Penicillium rubens MABC05 and Their Anti-Ferroptotic and Cytotoxic Activities.

Συγγραφείς: Liu L; Key Laboratory of Tropical Biological Resources of Ministry of Education, School of Pharmaceutical Sciences, Hainan University, Haikou 570228, China., Yang X; Key Laboratory of Tropical Biological Resources of Ministry of Education, School of Pharmaceutical Sciences, Hainan University, Haikou 570228, China., Hu C; Key Laboratory of Tropical Biological Resources of Ministry of Education, School of Pharmaceutical Sciences, Hainan University, Haikou 570228, China., Wang P; Key Laboratory of Tropical Biological Resources of Ministry of Education, School of Pharmaceutical Sciences, Hainan University, Haikou 570228, China., Luo Z; Key Laboratory of Marine Biogenetic Resources, Third Institute of Oceanography, Ministry of Natural Resources, Xiamen 361005, China., Lv Q; Key Laboratory of Tropical Biological Resources of Ministry of Education, School of Pharmaceutical Sciences, Hainan University, Haikou 570228, China., Zhang Y; Key Laboratory of Tropical Biological Resources of Ministry of Education, School of Pharmaceutical Sciences, Hainan University, Haikou 570228, China., Cheng Z; Key Laboratory of Tropical Biological Resources of Ministry of Education, School of Pharmaceutical Sciences, Hainan University, Haikou 570228, China.

Πηγή: Marine drugs [Mar Drugs] 2026 Sep 17; Vol. 24 (9). Date of Electronic Publication: 2026 Sep 17.

Τύπος έκδοσης: Journal Article

Στοιχεία περιοδικού: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101213729 Publication Model: Electronic Cited Medium: Internet ISSN: 1660-3397 (Electronic) Linking ISSN: 16603397 NLM ISO Abbreviation: Mar Drugs Subsets: MEDLINE

Ιατρικοί όροι (MeSH): Penicillium*/chemistry , Polycyclic Sesquiterpenes*/pharmacology , Polycyclic Sesquiterpenes*/chemistry , Pyrones*/pharmacology , Pyrones*/chemistry , Pyrones*/isolation & purification , Terpenes*/pharmacology , Terpenes*/chemistry , Terpenes*/isolation & purification, Kidney Tubules, Proximal/drug effects ; Humans ; Crystallography, X-Ray ; Molecular Structure

Oxygen-to-Sulfur Coordination Switching in Kojic Acid Ligands Tunes the Electronics and Anticancer Activity of Ru(II)-Diphosphine Complexes against Glioblastoma Cells.

Συγγραφείς: Saha A; Department of Chemistry, Indian Institute of Technology Kanpur, Kanpur, U.P.208016, India., Singh RR; Department of Biochemical Engineering & Biotechnology, Indian Institute of Technology Delhi, Hauz Khas, New Delhi110016, India.; University of Queensland-IIT Delhi Research Academy, Indian Institute of Technology Delhi, Hauz Khas, New Delhi110016, India., Butcher RJ; Department of Chemistry, Howard University, Washington, District of Columbia20059, United States., Kulshreshtha R; Department of Biochemical Engineering & Biotechnology, Indian Institute of Technology Delhi, Hauz Khas, New Delhi110016, India., Patra AK; Department of Chemistry, Indian Institute of Technology Kanpur, Kanpur, U.P.208016, India.

Πηγή: Inorganic chemistry [Inorg Chem] 2026 Sep 14; Vol. 65 (36), pp. 20786-20804.

Τύπος έκδοσης: Journal Article

Στοιχεία περιοδικού: Publisher: American Chemical Society Country of Publication: United States NLM ID: 0366543 Publication Model: Print Cited Medium: Internet ISSN: 1520-510X (Electronic) Linking ISSN: 00201669 NLM ISO Abbreviation: Inorg Chem Subsets: MEDLINE

Ιατρικοί όροι (MeSH): Pyrones*/chemistry , Pyrones*/pharmacology , Ruthenium*/chemistry , Ruthenium*/pharmacology , Antineoplastic Agents*/pharmacology , Antineoplastic Agents*/chemistry , Antineoplastic Agents*/chemical synthesis , Coordination Complexes*/pharmacology , Coordination Complexes*/chemistry , Coordination Complexes*/chemical synthesis , Glioblastoma*/pathology , Glioblastoma*/drug therapy , Phosphines*/chemistry , Phosphines*/pharmacology , Sulfur*/chemistry , Oxygen*/chemistry, Cell Proliferation/drug effects ; Humans ; Ligands ; Drug Screening Assays, Antitumor ; Cell Line, Tumor ; Molecular Structure ; Models, Molecular ; Crystallography, X-Ray

Multimethod-guided discovery of novel α-pyrone dimers with cardiomyocyte-protective activity against cold ischemia injury from the coral-derived Talaromyces sp. TJ403-AL05.

Συγγραφείς: Zeng H; Hubei Key Laboratory of Natural Medicinal Chemistry and Resource Evaluation, School of Pharmacy, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China., Wang Y; Hubei Key Laboratory of Natural Medicinal Chemistry and Resource Evaluation, School of Pharmacy, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China., Huang C; Department of Oncology, The First Affiliated Hospital of Henan University, Kaifeng 475001, China., Jiang R; Hubei Key Laboratory of Natural Medicinal Chemistry and Resource Evaluation, School of Pharmacy, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China., Zhang Y; Hubei Key Laboratory of Natural Medicinal Chemistry and Resource Evaluation, School of Pharmacy, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China., Chai Z; Hubei Key Laboratory of Natural Medicinal Chemistry and Resource Evaluation, School of Pharmacy, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China., Chi J; State Key Laboratory of Biocatalysis and Enzyme Engineering, School of Life Sciences, Hubei University, Wuhan 430062, China. Electronic address: chijiangyang@163.com., Zhang Y; Hubei Key Laboratory of Natural Medicinal Chemistry and Resource Evaluation, School of Pharmacy, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China. Electronic address: zhangyh@mails.tjmu.edu.cn., Hu Z; Hubei Key Laboratory of Natural Medicinal Chemistry and Resource Evaluation, School of Pharmacy, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China; Hubei Jiangxia Laboratory, Wuhan 430200, China; Hubei Shizhen Laboratory, Wuhan 430061, China. Electronic address: hzx616@126.com.

Πηγή: Chinese journal of natural medicines [Chin J Nat Med] 2026 Sep; Vol. 24 (9), pp. 1110-1122.

Τύπος έκδοσης: Journal Article

Στοιχεία περιοδικού: Publisher: Science Press Country of Publication: China NLM ID: 101504416 Publication Model: Print Cited Medium: Internet ISSN: 1875-5364 (Electronic) Linking ISSN: 18755364 NLM ISO Abbreviation: Chin J Nat Med Subsets: MEDLINE

Ιατρικοί όροι (MeSH): Talaromyces*/chemistry , Myocytes, Cardiac*/drug effects , Myocytes, Cardiac*/metabolism , Pyrones*/chemistry , Pyrones*/pharmacology , Pyrones*/isolation & purification , Anthozoa*/microbiology , Cardiotonic Agents*/pharmacology , Cardiotonic Agents*/chemistry, Animals ; Humans ; Molecular Structure ; Dimerization

Safety and Efficacy of Oral Ferric Maltol and Ferrous Sulfate for Iron Deficiency Anemia in Infants, Children and Adolescents: A Multicenter Randomized Trial.

Συγγραφείς: Gass D; Atrium Health, Levine Children's Hospital, Charlotte, USA., Freiberg A; Penn State Health, Lancaster, USA., Auth MKH; Alder Hey Hospital, Children's NHS Foundation Trust, Liverpool, UK.; University of Liverpool, Liverpool, UK., Russell RK; NHS Scotland, Edinburgh, UK. richard.russell@nhs.scot.; Department of Paediatric Gastroenterology, Royal Hospital for Children and Young People, Clinical Staff Offices, 2nd Floor, 50 Little France Crescent, Edinburgh, EH16 4TJ, UK. richard.russell@nhs.scot.

Πηγή: Paediatric drugs [Paediatr Drugs] 2026 Sep; Vol. 28 (5), pp. 531-545. Date of Electronic Publication: 2026 Jul 15.

Τύπος έκδοσης: Clinical Trial, Phase III; Comparative Study; Journal Article; Multicenter Study; Randomized Controlled Trial

Στοιχεία περιοδικού: Publisher: Springer International Country of Publication: Switzerland NLM ID: 100883685 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1179-2019 (Electronic) Linking ISSN: 11745878 NLM ISO Abbreviation: Paediatr Drugs Subsets: MEDLINE

Ιατρικοί όροι (MeSH): Anemia, Iron-Deficiency*/drug therapy , Anemia, Iron-Deficiency*/blood , Ferric Compounds*/adverse effects , Ferric Compounds*/administration & dosage , Ferric Compounds*/therapeutic use , Ferric Compounds*/pharmacokinetics , Ferrous Compounds*/adverse effects , Ferrous Compounds*/administration & dosage , Ferrous Compounds*/therapeutic use , Ferrous Compounds*/pharmacokinetics , Pyrones*/adverse effects , Pyrones*/administration & dosage , Pyrones*/therapeutic use , Pyrones*/pharmacokinetics, Hemoglobins/analysis ; Adolescent ; Child ; Child, Preschool ; Female ; Humans ; Infant ; Male ; Administration, Oral ; Treatment Outcome

Preparation, characterization and in-vitro anti-cholestatic activity of swertiamarin-loaded galactosylated solid lipid nanoparticle.

Συγγραφείς: Wu T; Central Laboratory, Hubei Key Laboratory of Sports Injury and Precision Therapy, Wuhan Fourth Hospital, Wuhan, China, 430033., Guan X; Central Laboratory, Hubei Key Laboratory of Sports Injury and Precision Therapy, Wuhan Fourth Hospital, Wuhan, China, 430033., He W; Central Laboratory, Hubei Key Laboratory of Sports Injury and Precision Therapy, Wuhan Fourth Hospital, Wuhan, China, 430033., Zhu X; Central Laboratory, Hubei Key Laboratory of Sports Injury and Precision Therapy, Wuhan Fourth Hospital, Wuhan, China, 430033., Lei L; Central Laboratory, Hubei Key Laboratory of Sports Injury and Precision Therapy, Wuhan Fourth Hospital, Wuhan, China, 430033.

Πηγή: Pakistan journal of pharmaceutical sciences [Pak J Pharm Sci] 2026 Sep; Vol. 39 (9), pp. 2816-2824.

Τύπος έκδοσης: Journal Article

Στοιχεία περιοδικού: Publisher: Faculty of Pharmacy, University of Karachi Country of Publication: Pakistan NLM ID: 9426356 Publication Model: Print Cited Medium: Internet ISSN: 3105-9686 (Electronic) Linking ISSN: 1011601X NLM ISO Abbreviation: Pak J Pharm Sci Subsets: MEDLINE

Ιατρικοί όροι (MeSH): Nanoparticles*/chemistry , Pyrones*/chemistry , Pyrones*/pharmacology , Iridoid Glucosides*/chemistry , Iridoid Glucosides*/pharmacology , Cholestasis, Intrahepatic*/drug therapy , Liposomes*, Drug Carriers/chemistry ; Glycosylation ; Particle Size ; Humans ; Hep G2 Cells ; Molecular Structure

Kavalactone profiling of Piper methysticum root and rhizome extracts and the modulation of CYP450 activity in vitro.

Συγγραφείς: Daniels T; Sonoran University of Health Sciences, The Ric Scalzo Institute for Botanical Research, 2140 E. Broadway Rd., Tempe, AZ, 85282, USA., Puchalski K; Sonoran University of Health Sciences, The Ric Scalzo Institute for Botanical Research, 2140 E. Broadway Rd., Tempe, AZ, 85282, USA., Trapp S; Sonoran University of Health Sciences, The Ric Scalzo Institute for Botanical Research, 2140 E. Broadway Rd., Tempe, AZ, 85282, USA., Jimoh A; Sonoran University of Health Sciences, The Ric Scalzo Institute for Botanical Research, 2140 E. Broadway Rd., Tempe, AZ, 85282, USA., Baravati B; Sonoran University of Health Sciences, The Ric Scalzo Institute for Botanical Research, 2140 E. Broadway Rd., Tempe, AZ, 85282, USA., Shokoohinia Y; Sonoran University of Health Sciences, The Ric Scalzo Institute for Botanical Research, 2140 E. Broadway Rd., Tempe, AZ, 85282, USA., Smith S; Thorne Research, Inc., 620 Omni Industrial Blvd, Summerville, SC, 29486, USA., Langland J; Sonoran University of Health Sciences, The Ric Scalzo Institute for Botanical Research, 2140 E. Broadway Rd., Tempe, AZ, 85282, USA. Electronic address: j.langland@sonoran.edu.

Πηγή: Chemico-biological interactions [Chem Biol Interact] 2026 Sep 01; Vol. 437, pp. 112219. Date of Electronic Publication: 2026 Jul 10.

Τύπος έκδοσης: Journal Article

Στοιχεία περιοδικού: Publisher: Elsevier Country of Publication: Ireland NLM ID: 0227276 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1872-7786 (Electronic) Linking ISSN: 00092797 NLM ISO Abbreviation: Chem Biol Interact Subsets: MEDLINE

Ιατρικοί όροι (MeSH): Kava*/chemistry , Kava*/metabolism , Plant Extracts*/chemistry , Plant Extracts*/pharmacology , Pyrones*/analysis , Pyrones*/chemistry , Pyrones*/pharmacology , Pyrones*/toxicity , Cytochrome P-450 Enzyme System*/metabolism , Lactones*/chemistry , Lactones*/analysis , Lactones*/pharmacology, Plant Roots/chemistry ; Plant Roots/metabolism ; Hepatocytes/drug effects ; Hepatocytes/metabolism ; Hepatocytes/cytology ; Rhizome/chemistry ; Rhizome/metabolism ; Pyrans/analysis ; Pyrans/chemistry ; Pyrans/pharmacology ; Cytochrome P-450 CYP3A/metabolism ; Cytochrome P-450 Enzyme Inhibitors/pharmacology ; Humans ; Chromatography, High Pressure Liquid ; Flavonoids ; Cytochrome P-450 CYP1A2

Hispidin-enriched Sanhuangporus sanghuang ethanolic extract: A novel GLP-1 inducer with non-mutagenic properties.

Συγγραφείς: Chen YY; Biotech Research Institute, Grape King Bio Ltd., Taoyuan 325, Taiwan., Lin TW; Biotech Research Institute, Grape King Bio Ltd., Taoyuan 325, Taiwan., Chu HT; Biotech Research Institute, Grape King Bio Ltd., Taoyuan 325, Taiwan., Li TJ; Biotech Research Institute, Grape King Bio Ltd., Taoyuan 325, Taiwan., Chu YL; Department of Food Science, College of Agriculture National Pingtung University of Science and Technology, Pingtung County 912, Taiwan., Li IC; Biotech Research Institute, Grape King Bio Ltd., Taoyuan 325, Taiwan. Electronic address: ichen.li@grapeking.com.tw., Chen CC; Biotech Research Institute, Grape King Bio Ltd., Taoyuan 325, Taiwan; Institute of Food Science and Technology, National Taiwan University, Taipei 106, Taiwan; Department of Bioscience Technology, Chung Yuan Christian University, Taoyuan 320, Taiwan; Institute of BioPharmaceutical Science, National Sun Yat-sen University, Kaohsiung 804, Taiwan. Electronic address: gkbioeng@grapeking.com.tw.

Πηγή: Fitoterapia [Fitoterapia] 2026 Sep; Vol. 193, pp. 107355. Date of Electronic Publication: 2026 Jun 30.

Τύπος έκδοσης: Journal Article

Στοιχεία περιοδικού: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 16930290R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-6971 (Electronic) Linking ISSN: 0367326X NLM ISO Abbreviation: Fitoterapia Subsets: MEDLINE

Ιατρικοί όροι (MeSH): Glucagon-Like Peptide 1*/metabolism , Pyrones*/pharmacology , Pyrones*/chemistry , Pyrones*/isolation & purification , Hypoglycemic Agents*/pharmacology, Ethanol/chemistry ; Molecular Docking Simulation ; Animals ; Humans ; Mice ; Micronucleus Tests

Goniothalamin as a Styryl-Lactone Toxicophore in Cancer Models: Electrophile-Driven DNA Damage, Reactive Oxygen Species-Endoplasmic Reticulum Stress Signaling and Detoxification-Relevant Safety Considerations.

Συγγραφείς: Joković N; Department of Biology and Ecology, Faculty of Science and Mathematics, University of Niš, Niš, Serbia., Pešić S; Department of Biology and Ecology, Faculty of Science and Mathematics, University of Niš, Niš, Serbia., Novaković M; Department of Biology and Ecology, Faculty of Science and Mathematics, University of Niš, Niš, Serbia., Krstić AD; Department of Biology and Ecology, Faculty of Science and Mathematics, University of Niš, Niš, Serbia., Setzer WN; Aromatic Plant Research Center, Lehi, Utah, USA.; Department of Chemistry, University of Alabama in Huntsville, Huntsville, Alabama, USA., Sharifi-Rad J; Universidad Espíritu Santo, Samborondón, Ecuador.; Department of Medicine, College of Medicine, Korea University, Seoul, Republic of Korea.; Centro de Estudios Tecnológicos y Universitarios del Golfo, Veracruz, Mexico., Calina D; Department of Clinical Pharmacy, University of Medicine and Pharmacy of Craiova, Craiova, Romania.

Πηγή: Journal of biochemical and molecular toxicology [J Biochem Mol Toxicol] 2026 Aug; Vol. 40 (8), pp. e71040.

Τύπος έκδοσης: Journal Article; Review

Στοιχεία περιοδικού: Publisher: Wiley Country of Publication: United States NLM ID: 9717231 Publication Model: Print Cited Medium: Internet ISSN: 1099-0461 (Electronic) Linking ISSN: 10956670 NLM ISO Abbreviation: J Biochem Mol Toxicol Subsets: MEDLINE

Ιατρικοί όροι (MeSH): Pyrones*/chemistry , Pyrones*/pharmacology , Pyrones*/therapeutic use , Neoplasms*/drug therapy , Neoplasms*/metabolism , Neoplasms*/pathology, Antineoplastic Agents/pharmacology ; Endoplasmic Reticulum Stress/drug effects ; Reactive Oxygen Species/metabolism ; DNA Damage/drug effects ; Signal Transduction/drug effects ; Humans

Study on the structure-activity relationships of natural γ-pyranone products and their derivatives with anti-AD activities focusing on metal chelation.

Συγγραφείς: Mao J; School of Chinese Materia Medica, Tianjin University of Traditional Chinese Medicine, Tianjin, 301617, China., Wang C; Bijie Institute of Traditional Chinese Medicine, Bijie, 551700, China.; Guizhou Key Laboratory for Germplasm Innovation and Resource-Efficient Utilization of Dao-Di Herbs, Guizhou, 550025, China., Li X; School of Chinese Materia Medica, Tianjin University of Traditional Chinese Medicine, Tianjin, 301617, China., Du R; School of Chinese Materia Medica, Tianjin University of Traditional Chinese Medicine, Tianjin, 301617, China., Zhang X; Bijie Institute of Traditional Chinese Medicine, Bijie, 551700, China.; Guizhou Key Laboratory for Germplasm Innovation and Resource-Efficient Utilization of Dao-Di Herbs, Guizhou, 550025, China., Shen R; School of Chinese Materia Medica, Tianjin University of Traditional Chinese Medicine, Tianjin, 301617, China. shenr2016@126.com., Yang A; School of Chinese Materia Medica, Tianjin University of Traditional Chinese Medicine, Tianjin, 301617, China. yah408@163.com., Kou X; School of Chinese Materia Medica, Tianjin University of Traditional Chinese Medicine, Tianjin, 301617, China. xiaodikou2013@163.com.

Πηγή: Molecular diversity [Mol Divers] 2026 Aug; Vol. 30 (4), pp. 4701-4717. Date of Electronic Publication: 2025 Dec 03.

Τύπος έκδοσης: Journal Article; Review

Στοιχεία περιοδικού: Publisher: ESCOM Science Publishers Country of Publication: Netherlands NLM ID: 9516534 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1573-501X (Electronic) Linking ISSN: 13811991 NLM ISO Abbreviation: Mol Divers Subsets: MEDLINE

Ιατρικοί όροι (MeSH): Alzheimer Disease*/drug therapy , Alzheimer Disease*/metabolism , Biological Products*/chemistry , Biological Products*/pharmacology , Biological Products*/therapeutic use , Chelating Agents*/chemistry , Chelating Agents*/pharmacology , Chelating Agents*/therapeutic use , Metals*/chemistry , Pyrones*/chemistry , Pyrones*/pharmacology , Pyrones*/therapeutic use, Structure-Activity Relationship ; Humans ; Animals

The pan-AMPK activator MK-8722 outperforms the AMPK activators SC4 and A-769662 in human endothelial cells.

Συγγραφείς: Doshi H; Institute for Molecular Cell Biology, Center for Molecular Biomedicine, Jena University Hospital, 07745 Jena, Germany., Spengler K; Institute for Molecular Cell Biology, Center for Molecular Biomedicine, Jena University Hospital, 07745 Jena, Germany., Siniuk K; Leibniz Institute on Aging- Fritz Lipmann Institute (FLI), 07745 Jena, Germany., Groth M; Leibniz Institute on Aging- Fritz Lipmann Institute (FLI), 07745 Jena, Germany., Heyne E; Department of Cardiothoracic Surgery, Jena University Hospital, 07747 Jena, Germany., Schwarzer M; Department of Cardiothoracic Surgery, Jena University Hospital, 07747 Jena, Germany., Godbole A; Institute for Molecular Cell Biology, Center for Molecular Biomedicine, Jena University Hospital, 07745 Jena, Germany., Gee YS; Medicinal Chemistry, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville 3052, Australia., Baell J; Medicinal Chemistry, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville 3052, Australia.; School of Pharmaceutical Sciences, Nanjing Tech University, Nanjing 211816, People's Republic of China., Oakhill JS; Metabolic Signaling Laboratory, St. Vincent's Institute of Medical Research, Fitzroy 3065, Australia.; Faculty of Health Sciences, Australian Catholic University, Melbourne 3065, Australia., Henke A; Section of Experimental Virology, Institute of Medical Microbiology, Jena University Hospital, 07745 Jena, Germany., Heller R; Institute for Molecular Cell Biology, Center for Molecular Biomedicine, Jena University Hospital, 07745 Jena, Germany.

Πηγή: Bioscience reports [Biosci Rep] 2026 Oct 21; Vol. 46 (10).

Τύπος έκδοσης: Journal Article

Στοιχεία περιοδικού: Publisher: Portland Press on behalf of the Biochemical Society Country of Publication: England NLM ID: 8102797 Publication Model: Print Cited Medium: Internet ISSN: 1573-4935 (Electronic) Linking ISSN: 01448463 NLM ISO Abbreviation: Biosci Rep Subsets: MEDLINE

Ιατρικοί όροι (MeSH): Thiophenes*/pharmacology , AMP-Activated Protein Kinases*/metabolism , Pyrones*/pharmacology , Endothelial Cells*/drug effects , Endothelial Cells*/enzymology , Enzyme Activators*/pharmacology , Resorcinols*/pharmacology, Enzyme Activation/drug effects ; Phosphorylation/drug effects ; Human Umbilical Vein Endothelial Cells/drug effects ; Humans ; Biphenyl Compounds

Allantopyrone A promotes cross-linking of ubiquitin-specific protease 5 (USP5) and inhibits its deubiquitinase activity by targeting distinct domains.

Συγγραφείς: Okuda C; Department of Applied Biology, Kyoto Institute of Technology, Kyoto, Japan., Tokumori S; Department of Applied Biology, Kyoto Institute of Technology, Kyoto, Japan., Vu NT; Department of Applied Biology, Kyoto Institute of Technology, Kyoto, Japan., Muroi M; Biomolecular Characterization Unit, Technology Platform Division, RIKEN Center for Sustainable Resource Science, Saitama, Japan.; Chemical Resource Development Research Unit, Technology Platform Division, RIKEN Center for Sustainable Resource Science, Saitama, Japan., Sanada E; Chemical Resource Development Research Unit, Technology Platform Division, RIKEN Center for Sustainable Resource Science, Saitama, Japan., Suzuki T; Biomolecular Characterization Unit, Technology Platform Division, RIKEN Center for Sustainable Resource Science, Saitama, Japan., Dohmae N; Biomolecular Characterization Unit, Technology Platform Division, RIKEN Center for Sustainable Resource Science, Saitama, Japan., Osada H; Chemical Resource Development Research Unit, Technology Platform Division, RIKEN Center for Sustainable Resource Science, Saitama, Japan.; Institute of Microbial Chemistry (BIKAKEN), Shinagawa, Japan., Shiono Y; Department of Food, Life, and Environmental Science, Faculty of Agriculture, Yamagata University, Yamagata, Japan., Kimura KI; The United Graduate School of Agricultural Sciences, Iwate University, Iwate, Japan., Kumada Y; Department of Functional Chemistry and Engineering, Kyoto Institute of Technology, Kyoto, Japan., Shiba T; Department of Applied Biology, Kyoto Institute of Technology, Kyoto, Japan., Komada M; Cell Biology Center, Institute of Integrated Research, Institute of Science Tokyo, Yokohama, Japan., Fukushima T; Cell Biology Center, Institute of Integrated Research, Institute of Science Tokyo, Yokohama, Japan., Kataoka T; Department of Applied Biology, Kyoto Institute of Technology, Kyoto, Japan. takao.kataoka@kit.ac.jp.; Center for Social and Biomedical Engineering, Kyoto Institute of Technology, Kyoto, Japan. takao.kataoka@kit.ac.jp.

Πηγή: The Journal of antibiotics [J Antibiot (Tokyo)] 2026 Oct; Vol. 79 (10), pp. 673-686. Date of Electronic Publication: 2026 Jul 14.

Τύπος έκδοσης: Journal Article

Στοιχεία περιοδικού: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 0151115 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1881-1469 (Electronic) Linking ISSN: 00218820 NLM ISO Abbreviation: J Antibiot (Tokyo) Subsets: MEDLINE

Ιατρικοί όροι (MeSH): Ubiquitin-Specific Proteases*/metabolism , Ubiquitin-Specific Proteases*/chemistry , Deubiquitinating Enzymes*/antagonists & inhibitors , Deubiquitinating Enzymes*/metabolism , Pyrones*/pharmacology, Proteasome Endopeptidase Complex/metabolism ; Humans ; Mass Spectrometry

Inhibition of maltol on enzymatic browning in potato: Combined effects on PPO activity, substrate biosynthesis, and oxidative stress.

Συγγραφείς: Chang X; State Key Laboratory of Food Science and Resources, Nanchang University, Nanchang 330047, China., Fan P; State Key Laboratory of Food Science and Resources, Nanchang University, Nanchang 330047, China., Liang Z; State Key Laboratory of Food Science and Resources, Nanchang University, Nanchang 330047, China., Lu X; State Key Laboratory of Food Science and Resources, Nanchang University, Nanchang 330047, China., Liu J; State Key Laboratory of Food Science and Resources, Nanchang University, Nanchang 330047, China., Liu W; State Key Laboratory of Food Science and Resources, Nanchang University, Nanchang 330047, China; International Institute of Food Innovation Co, Ltd., Nanchang University, Nanchang 330047, China., Zhang X; Tobacco Science Institute of Jiangxi Province, Nanchang 330025, China., Jiao S; Tobacco Science Institute of Jiangxi Province, Nanchang 330025, China., Zhou L; State Key Laboratory of Food Science and Resources, Nanchang University, Nanchang 330047, China; International Institute of Food Innovation Co, Ltd., Nanchang University, Nanchang 330047, China. Electronic address: ncuskzhoulei@163.com.

Πηγή: Food chemistry [Food Chem] 2026 Oct 01; Vol. 525 (Pt 1), pp. 150335. Date of Electronic Publication: 2026 Jul 07.

Τύπος έκδοσης: Journal Article

Στοιχεία περιοδικού: Publisher: Elsevier Applied Science Publishers Country of Publication: England NLM ID: 7702639 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-7072 (Electronic) Linking ISSN: 03088146 NLM ISO Abbreviation: Food Chem Subsets: MEDLINE

Ιατρικοί όροι (MeSH): Solanum tuberosum*/chemistry , Solanum tuberosum*/enzymology , Solanum tuberosum*/drug effects , Solanum tuberosum*/metabolism , Catechol Oxidase*/metabolism , Catechol Oxidase*/antagonists & inhibitors , Catechol Oxidase*/chemistry , Pyrones*/pharmacology , Plant Proteins*/metabolism , Plant Proteins*/chemistry , Plant Proteins*/antagonists & inhibitors , Enzyme Inhibitors*/pharmacology, Oxidative Stress/drug effects ; Maillard Reaction/drug effects ; Plant Tubers/enzymology ; Plant Tubers/drug effects ; Plant Tubers/chemistry ; Plant Tubers/metabolism ; Catalase/metabolism

The AMPK-PGC-1α-SIRT3 axis mediates mitochondrial metabolic dysfunction and neuronal senescence induced by Al(mal)3 exposure in HT22 hippocampal neuronal cells.

Συγγραφείς: Zhang H; Department of Occupational Health, School of Public Health, Shanxi Medical University, Taiyuan, China; MOE Key Laboratory of Coal Environmental Pathogenicity and Prevention in Shanxi, Taiyuan, China. Electronic address: zhf201101@sxmu.edu.cn., Gao X; Department of Occupational Health, School of Public Health, Shanxi Medical University, Taiyuan, China; MOE Key Laboratory of Coal Environmental Pathogenicity and Prevention in Shanxi, Taiyuan, China., Jin Z; Department of Occupational Health, School of Public Health, Shanxi Medical University, Taiyuan, China; MOE Key Laboratory of Coal Environmental Pathogenicity and Prevention in Shanxi, Taiyuan, China., Liu Y; Department of Occupational Health, School of Public Health, Shanxi Medical University, Taiyuan, China; MOE Key Laboratory of Coal Environmental Pathogenicity and Prevention in Shanxi, Taiyuan, China., Yin J; Department of Neurosurgery, Datong Key Laboratory of Nervous Systems Disease Prevention and Treatment for Coal Mine Workers, Shanxi Health Commission Key Laboratory of Nervous System Disease Prevention and Treatment, Sinopharm Tongmei General Hospital, Datong, Shanxi, 037003, China., Zhang R; Fifth Hospital of Shanxi Medical University, Taiyuan, China. Electronic address: zhangrui_gc@163.com.

Πηγή: Free radical biology & medicine [Free Radic Biol Med] 2026 Oct; Vol. 254, pp. 78-90. Date of Electronic Publication: 2026 Jun 09.

Τύπος έκδοσης: Journal Article

Στοιχεία περιοδικού: Publisher: Elsevier Science Country of Publication: United States NLM ID: 8709159 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-4596 (Electronic) Linking ISSN: 08915849 NLM ISO Abbreviation: Free Radic Biol Med Subsets: MEDLINE

Ιατρικοί όροι (MeSH): Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha*/metabolism , Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha*/genetics , Mitochondria*/drug effects , Mitochondria*/metabolism , Mitochondria*/pathology , Cellular Senescence*/drug effects , Hippocampus*/drug effects , Hippocampus*/metabolism , Hippocampus*/pathology , Hippocampus*/cytology , Neurons*/drug effects , Neurons*/metabolism , Neurons*/pathology , Pyrones*/toxicity , AMP-Activated Protein Kinases*/metabolism , AMP-Activated Protein Kinases*/genetics , Sirtuin 3*/metabolism , Sirtuin 3*/genetics , Organometallic Compounds*/toxicity, Signal Transduction/drug effects ; Isocitrate Dehydrogenase/metabolism ; Isocitrate Dehydrogenase/genetics ; Aminoimidazole Carboxamide/analogs & derivatives ; Aminoimidazole Carboxamide/pharmacology ; Superoxide Dismutase/metabolism ; Superoxide Dismutase/genetics ; Ribonucleotides/pharmacology ; Glycolysis/drug effects ; Aluminum/toxicity ; beta-Galactosidase/metabolism ; beta-Galactosidase/genetics ; Animals ; Mice ; Superoxide Dismutase 2 ; Cell Line