Pharmacovigilance and toxicological studies on safety signals associated with the combined use of propofol and midazolam.

Authors: Wei W; Department of Anesthesiology and Pain Research Center, The Affiliated Hospital of Jiaxing University & The First Hospital of Jiaxing, Jiaxing, Zhejiang, China., Wang L; Department of Anesthesiology and Pain Research Center, The Affiliated Hospital of Jiaxing University & The First Hospital of Jiaxing, Jiaxing, Zhejiang, China., Chen L; Department of Hepatobiliary and Pancreatic Surgery, Conversion therapy center for Hepatobiliary and Pancreatic Tumors, The Affiliated Hospital of Jiaxing University & The First Hospital of Jiaxing, Jiaxing, Zhejiang, China., Ying X; Suzhou Hospital of Anhui Medical University, Anhui, Suzhou, China., Xu S; Department of Anesthesiology and Pain Research Center, The Affiliated Hospital of Jiaxing University & The First Hospital of Jiaxing, Jiaxing, Zhejiang, China. 1813110760@qq.com.

Source: BMC anesthesiology [BMC Anesthesiol] 2026 Apr 21; Vol. 26 (1). Date of Electronic Publication: 2026 Apr 21.

Publication Type: Journal Article

Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 100968535 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-2253 (Electronic) Linking ISSN: 14712253 NLM ISO Abbreviation: BMC Anesthesiol Subsets: MEDLINE

MeSH Terms: Midazolam*/adverse effects , Midazolam*/administration & dosage , Propofol*/adverse effects , Propofol*/administration & dosage , Hypnotics and Sedatives*/adverse effects , Hypnotics and Sedatives*/administration & dosage , Anesthetics, Intravenous*/adverse effects , Anesthetics, Intravenous*/administration & dosage , Anesthetics, Combined*/adverse effects , Anesthetics, Combined*/administration & dosage , Pharmacovigilance*, Propofol Infusion Syndrome/epidemiology ; Anaphylaxis/chemically induced ; Anaphylaxis/epidemiology ; Humans ; Databases, Factual

Neonatal propofol exposure induces region-specific neurotoxic proteomic signatures in mouse cortex and hippocampus.

Authors: Chen L; Department of Anesthesiology, the First Affiliated Hospital of Xiamen University, School of Medicine, Xiamen University, Xiamen 361003, China; Department of Anesthesiology, Department of Pediatrics, Women and Children's Hospital, School of Medicine, Xiamen University, Xiamen, Fujian 361102, China., Wang H; Department of Anesthesiology, The Fourth Hospital of Hebei Medical University, Shijiazhuang, Hebei 050010, China., Huang H; Department of Anesthesiology, the First Affiliated Hospital of Xiamen University, School of Medicine, Xiamen University, Xiamen 361003, China., Lin Y; Department of Anesthesiology, the First Affiliated Hospital of Xiamen University, School of Medicine, Xiamen University, Xiamen 361003, China., Gao H; Department of Anesthesiology, the First Affiliated Hospital of Xiamen University, School of Medicine, Xiamen University, Xiamen 361003, China. Electronic address: gaohaiying@xmu.edu.cn.

Source: Brain research [Brain Res] 2026 Oct 15; Vol. 1889, pp. 150477. Date of Electronic Publication: 2026 Jul 23.

Publication Type: Journal Article

Journal Info: Publisher: Elsevier/North-Holland Biomedical Press Country of Publication: Netherlands NLM ID: 0045503 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1872-6240 (Electronic) Linking ISSN: 00068993 NLM ISO Abbreviation: Brain Res Subsets: MEDLINE

MeSH Terms: Propofol*/pharmacology , Propofol*/toxicity , Hippocampus*/drug effects , Hippocampus*/metabolism , Cerebral Cortex*/drug effects , Cerebral Cortex*/metabolism, Proteomics/methods ; Exosomes/metabolism ; Exosomes/drug effects ; Proteome/metabolism ; Animals ; Mice, Inbred C57BL ; Mice ; Animals, Newborn ; Male ; Female

Lactoferrin-Modified Ultra-Sustained Release Propofol Nanoparticles for Multi-Pathway Therapy of Depression via Intraperitoneal Injection.

Authors: Wu Z; Department of Psychiatry and Center for Brain Science, the First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi, People's Republic of China.; Yan'an Medical College of Yan'an University, Yan'an, Shaanxi, People's Republic of China., Deng J; Department of Psychiatry and Center for Brain Science, the First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi, People's Republic of China.; Clinical Medical College, Shaanxi University of Chinese Medicine, Xianyang, Shaanxi, People's Republic of China., Li S; Department of Psychiatry and Center for Brain Science, the First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi, People's Republic of China.; Clinical Medical College, Shaanxi University of Chinese Medicine, Xianyang, Shaanxi, People's Republic of China., Yu L; Center for Translational Medicine, The First Affiliated Hospital of Xi' an Jiaotong University, Xi'an, Shaanxi, People's Republic of China., Zhang H; Department of Psychiatry and Center for Brain Science, the First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi, People's Republic of China.; Clinical Medical College, Shaanxi University of Chinese Medicine, Xianyang, Shaanxi, People's Republic of China., Xun Y; Center for Translational Medicine, The First Affiliated Hospital of Xi' an Jiaotong University, Xi'an, Shaanxi, People's Republic of China., Bian J; Department of Psychiatry and Center for Brain Science, the First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi, People's Republic of China., Liu J; Center for Translational Medicine, The First Affiliated Hospital of Xi' an Jiaotong University, Xi'an, Shaanxi, People's Republic of China., Zhang J; College of Forensic Medicine, Xi'an Jiaotong University, Xi'an, Shaanxi, People's Republic of China., Lei P; Department of Psychiatry and Center for Brain Science, the First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi, People's Republic of China., Ma Q; Department of Psychiatry and Center for Brain Science, the First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi, People's Republic of China., Fan Y; Department of Psychiatry and Center for Brain Science, the First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi, People's Republic of China., Yang Z; Department of Psychiatry and Center for Brain Science, the First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi, People's Republic of China., Zhu F; Department of Psychiatry and Center for Brain Science, the First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi, People's Republic of China., Ma X; Department of Psychiatry and Center for Brain Science, the First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi, People's Republic of China., Wu D; Key Laboratory of Biomedical Information Engineering of the Ministry of Education, School of Life Science and Technology, Xi'an Jiaotong University, Xi'an, Shaanxi, People's Republic of China., Zhang S; Department of Psychiatry and Center for Brain Science, the First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi, People's Republic of China.

Source: International journal of nanomedicine [Int J Nanomedicine] 2026 Oct 14; Vol. 21, pp. 645818. Date of Electronic Publication: 2026 Oct 14 (Print Publication: 2026).

Publication Type: Journal Article

Journal Info: Publisher: DOVE Medical Press Country of Publication: New Zealand NLM ID: 101263847 Publication Model: eCollection Cited Medium: Internet ISSN: 1178-2013 (Electronic) Linking ISSN: 11769114 NLM ISO Abbreviation: Int J Nanomedicine Subsets: MEDLINE

MeSH Terms: Propofol*/chemistry , Propofol*/pharmacokinetics , Propofol*/administration & dosage , Propofol*/pharmacology , Depression*/drug therapy , Nanoparticles*/chemistry , Nanoparticles*/administration & dosage , Lactoferrin*/chemistry , Lactoferrin*/pharmacokinetics , Antidepressive Agents*/pharmacokinetics , Antidepressive Agents*/chemistry , Antidepressive Agents*/administration & dosage , Antidepressive Agents*/pharmacology, Delayed-Action Preparations/chemistry ; Delayed-Action Preparations/pharmacokinetics ; Delayed-Action Preparations/administration & dosage ; Delayed-Action Preparations/pharmacology ; Brain/metabolism ; Brain/drug effects ; Animals ; Mice ; Injections, Intraperitoneal ; Male

Propofol for palliative sedation: A systematic review of clinical outcomes, safety, and ethical implications.

Authors: Almeida-Jardim L; Palliative Medicine Center, Faculty of Medicine, University of Lisbon, Lisboa, Portugal., Reis-Pina P; Palliative Medicine Center, Faculty of Medicine, University of Lisbon, Lisboa, Portugal.; Acute Palliative Care Inpatient Unit, Local Health Unit of Santa Maria, Lisboa, Portugal.

Source: Palliative medicine [Palliat Med] 2026 Oct; Vol. 40 (9), pp. 1302-1321. Date of Electronic Publication: 2026 Jul 31.

Publication Type: Systematic Review; Journal Article

Journal Info: Publisher: SAGE Publications Country of Publication: England NLM ID: 8704926 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1477-030X (Electronic) Linking ISSN: 02692163 NLM ISO Abbreviation: Palliat Med Subsets: MEDLINE

MeSH Terms: Propofol*/therapeutic use , Propofol*/adverse effects , Palliative Care*/methods , Palliative Care*/ethics , Hypnotics and Sedatives*/therapeutic use, Humans ; Female ; Adult ; Male

Transcriptomic characterization of prefrontal cortical remodeling and glutamate changes detected by Glu-CEST MRI in rats with propofol-induced neuroadaptations.

Authors: Huang Z; Department of Radiology, The First Affiliated Hospital of Shantou University Medical College, Shantou, 515041, China; Laboratory of Medical Molecular Imaging & Laboratory of Molecular Cardiology, The First Affiliated Hospital of Shantou University Medical College, Shantou, 515041, China., Zhuang Z; Department of Radiology, The First Affiliated Hospital of Shantou University Medical College, Shantou, 515041, China; Laboratory of Medical Molecular Imaging & Laboratory of Molecular Cardiology, The First Affiliated Hospital of Shantou University Medical College, Shantou, 515041, China., Huang Y; Department of Radiology, The First Affiliated Hospital of Shantou University Medical College, Shantou, 515041, China; Laboratory of Medical Molecular Imaging & Laboratory of Molecular Cardiology, The First Affiliated Hospital of Shantou University Medical College, Shantou, 515041, China., Shi X; Department of Radiology, The First Affiliated Hospital of Shantou University Medical College, Shantou, 515041, China., Guo B; Department of Radiology, The First Affiliated Hospital of Shantou University Medical College, Shantou, 515041, China; Laboratory of Medical Molecular Imaging & Laboratory of Molecular Cardiology, The First Affiliated Hospital of Shantou University Medical College, Shantou, 515041, China., Xu Z; Department of Radiology, The First Affiliated Hospital of Shantou University Medical College, Shantou, 515041, China; Laboratory of Medical Molecular Imaging & Laboratory of Molecular Cardiology, The First Affiliated Hospital of Shantou University Medical College, Shantou, 515041, China., Chen Y; Department of Radiology, The First Affiliated Hospital of Shantou University Medical College, Shantou, 515041, China; Laboratory of Medical Molecular Imaging & Laboratory of Molecular Cardiology, The First Affiliated Hospital of Shantou University Medical College, Shantou, 515041, China., Cao Y; Department of Radiology, The First Affiliated Hospital of Shantou University Medical College, Shantou, 515041, China; Laboratory of Medical Molecular Imaging & Laboratory of Molecular Cardiology, The First Affiliated Hospital of Shantou University Medical College, Shantou, 515041, China., Zheng Y; Department of Radiology, The First Affiliated Hospital of Shantou University Medical College, Shantou, 515041, China; Laboratory of Medical Molecular Imaging & Laboratory of Molecular Cardiology, The First Affiliated Hospital of Shantou University Medical College, Shantou, 515041, China., Xie L; Department of Radiology, The Cancer Hospital of Shantou University Medical College, Shantou, Guangdong, 515041, China. Electronic address: 13lxie1@stu.edu.cn., Wu R; Department of Radiology, The Second Affiliated Hospital of Shantou University Medical College, Shantou, China. Electronic address: hwu@stu.edu.cn., Ma S; Department of Radiology, The First Affiliated Hospital of Shantou University Medical College, Shantou, 515041, China; Laboratory of Medical Molecular Imaging & Laboratory of Molecular Cardiology, The First Affiliated Hospital of Shantou University Medical College, Shantou, 515041, China. Electronic address: shma@stu.edu.cn.

Source: Neurochemistry international [Neurochem Int] 2026 Oct; Vol. 199, pp. 106227. Date of Electronic Publication: 2026 Jul 20.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Pergamon Press Country of Publication: England NLM ID: 8006959 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1872-9754 (Electronic) Linking ISSN: 01970186 NLM ISO Abbreviation: Neurochem Int Subsets: MEDLINE

MeSH Terms: Propofol*/pharmacology , Propofol*/administration & dosage , Prefrontal Cortex*/drug effects , Prefrontal Cortex*/metabolism , Prefrontal Cortex*/diagnostic imaging , Glutamic Acid*/metabolism , Transcriptome*/drug effects , Transcriptome*/physiology , Magnetic Resonance Imaging*/methods , Anesthetics, Intravenous*/administration & dosage , Anesthetics, Intravenous*/pharmacology , Adaptation, Physiological*/drug effects , Adaptation, Physiological*/physiology , Neuronal Plasticity*/drug effects , Neuronal Plasticity*/physiology, Animals ; Rats ; Male ; Rats, Sprague-Dawley

Region-specific high-frequency oscillations under propofol anesthesia: comparison of epileptogenic and functional cortex.

Authors: Sakuraba-Hirata R; Department of Epileptology, Tohoku University Graduate School of Medicine, Japan; Department of Clinical Laboratory Sciences School of Health Sciences, Fukushima Medical University, Japan., Osawa SI; Department of Neurosurgery, Tohoku University Graduate School of Medicine, Japan. Electronic address: osws@tohoku.ac.jp., Ukishiro K; Department of Epileptology, Tohoku University Graduate School of Medicine, Japan., Iwasaki M; Department of Neurosurgery, National Center Hospital, National Center of Neurology and Psychiatry, Japan., Sugiyama SI; Department of Neuroanesthesia, Kohnan Hospital, Japan., Kakisaka Y; Tohoku University School of Medicine Office of Medical Education, Japan., Jin K; Department of Epileptology, Tohoku University Graduate School of Medicine, Japan., Uematsu M; Department of Pediatrics, Tohoku University Graduate School of Medicine, Japan., Okumura E; Department of Epileptology, Tohoku University Graduate School of Medicine, Japan., Horikoshi Y; Department of Clinical Laboratory Sciences School of Health Sciences, Fukushima Medical University, Japan., Nakasato N; Department of Epileptology, Tohoku University Graduate School of Medicine, Japan., Nishio Y; Department of Behavioral Neurology and Neuropsychiatry, Osaka University United Graduate School of Child Development, Japan., Suzuki K; Department of Behavioral and Cognitive Neuroscience, Tohoku University Graduate School of Medicine, Japan., Yoshihisa A; Department of Clinical Laboratory Sciences School of Health Sciences, Fukushima Medical University, Japan; Department of Cardiovascular Medicine, Fukushima Medical University, Japan., Endo H; Department of Neurosurgery, Tohoku University Graduate School of Medicine, Japan.

Source: Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology [Clin Neurophysiol] 2026 Oct; Vol. 190, pp. 2111982. Date of Electronic Publication: 2026 Jun 16.

Publication Type: Journal Article; Comparative Study

Journal Info: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 100883319 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1872-8952 (Electronic) Linking ISSN: 13882457 NLM ISO Abbreviation: Clin Neurophysiol Subsets: MEDLINE

MeSH Terms: Propofol*/administration & dosage , Propofol*/pharmacology , Cerebral Cortex*/physiopathology , Cerebral Cortex*/drug effects , Anesthetics, Intravenous*/administration & dosage , Anesthetics, Intravenous*/pharmacology , Drug Resistant Epilepsy*/physiopathology , Drug Resistant Epilepsy*/surgery , Brain Waves*/drug effects , Brain Waves*/physiology, Electroencephalography/methods ; Electrocorticography/methods ; Humans ; Female ; Male ; Retrospective Studies ; Adult ; Young Adult ; Adolescent

Differential Neurodevelopmental Toxicity of Propofol and Fospropofol: Mechanistic Insights and Potential Clinical Implications-A Zebrafish Model Study.

Authors: Liu Z; Department of Anesthesiology, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an 710061, China.; Department of Physiology and Pathophysiology, School of Basic Medical Sciences, Health Science Center, Xi'an Jiaotong University, Xi'an 710049, China., Deng Y; Department of Anesthesiology, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an 710061, China., Gao Y; Department of Anesthesiology, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an 710061, China.; Department of Physiology and Pathophysiology, School of Basic Medical Sciences, Health Science Center, Xi'an Jiaotong University, Xi'an 710049, China., Jia C; Department of Anesthesiology, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an 710061, China.; Department of Physiology and Pathophysiology, School of Basic Medical Sciences, Health Science Center, Xi'an Jiaotong University, Xi'an 710049, China., Zhao X; Department of Anesthesiology, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an 710061, China.; Department of Physiology and Pathophysiology, School of Basic Medical Sciences, Health Science Center, Xi'an Jiaotong University, Xi'an 710049, China., Tao L; Department of Anesthesiology, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an 710061, China.; Department of Physiology and Pathophysiology, School of Basic Medical Sciences, Health Science Center, Xi'an Jiaotong University, Xi'an 710049, China., Lai B; Cardiovascular Research Center, School of Basic Medical Sciences, Health Science Center, Xi'an Jiaotong University, Xi'an 710061, China., Chen X; Department of Anesthesiology, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an 710061, China., Li Y; Department of Anesthesiology, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an 710061, China., Han Y; Department of Anesthesiology, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an 710061, China.; Department of Physiology and Pathophysiology, School of Basic Medical Sciences, Health Science Center, Xi'an Jiaotong University, Xi'an 710049, China., Zhu Y; Department of Anesthesiology, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an 710061, China.

Source: International journal of molecular sciences [Int J Mol Sci] 2026 Sep 23; Vol. 27 (19). Date of Electronic Publication: 2026 Sep 23.

Publication Type: Journal Article

Journal Info: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067 (Electronic) Linking ISSN: 14220067 NLM ISO Abbreviation: Int J Mol Sci Subsets: MEDLINE

MeSH Terms: Propofol*/analogs & derivatives , Propofol*/toxicity , Zebrafish*/embryology , Anesthetics, Intravenous*/toxicity, Neurodevelopment/drug effects ; Embryo, Nonmammalian/drug effects ; Gene Expression Regulation, Developmental/drug effects ; Animals ; Molecular Docking Simulation

Comparison of Remimazolam and Propofol for Anesthesia Management in Liver Cancer Patients Undergoing Percutaneous Radiofrequency Ablation: A Randomized Controlled Trial.

Authors: Jiang P; Department of Anesthesia, Affiliated Hospital of North Sichuan Medical College, Nanchong, Sichuan, People's Republic of China., Deng M; Department of Surgery Center, Affiliated Hospital of North Sichuan Medical College, Nanchong, Sichuan, People's Republic of China., Wang Q; Department of Anesthesia, Affiliated Hospital of North Sichuan Medical College, Nanchong, Sichuan, People's Republic of China., Feng Y; Department of Anesthesia, Affiliated Hospital of North Sichuan Medical College, Nanchong, Sichuan, People's Republic of China., Wang D; Department of Anesthesia, Affiliated Hospital of North Sichuan Medical College, Nanchong, Sichuan, People's Republic of China., Chen X; Department of Anesthesia, Affiliated Hospital of North Sichuan Medical College, Nanchong, Sichuan, People's Republic of China.

Source: Drug design, development and therapy [Drug Des Devel Ther] 2026 Sep 22; Vol. 20, pp. 645319. Date of Electronic Publication: 2026 Sep 22 (Print Publication: 2026).

Publication Type: Journal Article; Randomized Controlled Trial; Comparative Study

Journal Info: Publisher: Dove Press Limited Country of Publication: New Zealand NLM ID: 101475745 Publication Model: eCollection Cited Medium: Internet ISSN: 1177-8881 (Electronic) Linking ISSN: 11778881 NLM ISO Abbreviation: Drug Des Devel Ther Subsets: MEDLINE

MeSH Terms: Propofol*/administration & dosage , Propofol*/therapeutic use , Propofol*/pharmacology , Liver Neoplasms*/surgery , Liver Neoplasms*/drug therapy , Carcinoma, Hepatocellular*/surgery , Radiofrequency Ablation*, Humans ; Female ; Male ; Middle Aged ; Aged ; Benzodiazepines

Comparison of Remimazolam and Propofol in Large Skull Base Tumor Resections: Effects on Hemodynamic Stability, Neurocognitive Recovery, and Inflammatory Response.

Authors: Huang L; Department of Anesthesiology, Jinan Central Hospital, Jinan, Shandong, 250013, People's Republic of China., Huang K; Operating Room, The Fourth People's Hospital of Jinan, Jinan, Shandong, 250031, People's Republic of China., Ning H; Department of Anesthesiology, Jinan Central Hospital, Jinan, Shandong, 250013, People's Republic of China., Zheng B; Department of Neurosurgery, The Second Affiliated Hospital of Shandong First Medical University, Tai'an, Shandong, 271000, People's Republic of China.

Source: Drug design, development and therapy [Drug Des Devel Ther] 2026 Sep 21; Vol. 20, pp. 642884. Date of Electronic Publication: 2026 Sep 21 (Print Publication: 2026).

Publication Type: Journal Article; Comparative Study

Journal Info: Publisher: Dove Press Limited Country of Publication: New Zealand NLM ID: 101475745 Publication Model: eCollection Cited Medium: Internet ISSN: 1177-8881 (Electronic) Linking ISSN: 11778881 NLM ISO Abbreviation: Drug Des Devel Ther Subsets: MEDLINE

MeSH Terms: Propofol*/pharmacology , Propofol*/administration & dosage , Hemodynamics*/drug effects , Inflammation*/drug therapy , Skull Base Neoplasms*/surgery , Skull Base Neoplasms*/drug therapy, Cognition/drug effects ; Humans ; Female ; Male ; Retrospective Studies ; Middle Aged ; Adult ; Aged

Fospropofol vs Propofol for Early Postoperative Nausea and Vomiting Prophylaxis in High-Risk Patients Undergoing Gynecological Laparoscopic Surgery: A Randomized Controlled Trial.

Authors: Ma L; Department of Anesthesiology, Obstetrics & Gynecology Hospital of Fudan University, Shanghai, 200433, People's Republic of China.; Shanghai Key Laboratory of Reproduction and Development, Shanghai, 200433, People's Republic of China., Guo Y; Department of Anesthesiology, Obstetrics & Gynecology Hospital of Fudan University, Shanghai, 200433, People's Republic of China.; Shanghai Key Laboratory of Reproduction and Development, Shanghai, 200433, People's Republic of China., Wang W; Department of Anesthesiology, Obstetrics & Gynecology Hospital of Fudan University, Shanghai, 200433, People's Republic of China.; Shanghai Key Laboratory of Reproduction and Development, Shanghai, 200433, People's Republic of China., Lin C; Department of Anesthesiology, Obstetrics & Gynecology Hospital of Fudan University, Shanghai, 200433, People's Republic of China.; Shanghai Key Laboratory of Reproduction and Development, Shanghai, 200433, People's Republic of China., Yuan Y; Department of Anesthesiology, Obstetrics & Gynecology Hospital of Fudan University, Shanghai, 200433, People's Republic of China.; Shanghai Key Laboratory of Reproduction and Development, Shanghai, 200433, People's Republic of China., Wu H; Department of Anesthesiology, Obstetrics & Gynecology Hospital of Fudan University, Shanghai, 200433, People's Republic of China.; Shanghai Key Laboratory of Reproduction and Development, Shanghai, 200433, People's Republic of China., Liu Z; Department of Anesthesiology, Obstetrics & Gynecology Hospital of Fudan University, Shanghai, 200433, People's Republic of China.; Shanghai Key Laboratory of Reproduction and Development, Shanghai, 200433, People's Republic of China., Du W; Department of Anesthesiology, Obstetrics & Gynecology Hospital of Fudan University, Shanghai, 200433, People's Republic of China.; Shanghai Key Laboratory of Reproduction and Development, Shanghai, 200433, People's Republic of China.

Source: Drug design, development and therapy [Drug Des Devel Ther] 2026 Sep 19; Vol. 20, pp. 636353. Date of Electronic Publication: 2026 Sep 19 (Print Publication: 2026).

Publication Type: Comparative Study; Journal Article; Randomized Controlled Trial

Journal Info: Publisher: Dove Press Limited Country of Publication: New Zealand NLM ID: 101475745 Publication Model: eCollection Cited Medium: Internet ISSN: 1177-8881 (Electronic) Linking ISSN: 11778881 NLM ISO Abbreviation: Drug Des Devel Ther Subsets: MEDLINE

MeSH Terms: Antiemetics*/administration & dosage , Gynecologic Surgical Procedures*/adverse effects , Laparoscopy*/adverse effects , Postoperative Nausea and Vomiting*/prevention & control , Postoperative Nausea and Vomiting*/drug therapy , Propofol*/administration & dosage , Propofol*/analogs & derivatives , Propofol*/analogs & derivatives, Adult ; Female ; Humans ; Middle Aged ; Prospective Studies

Combined Use of Etomidate and Propofol Reduce the Duration of Apnea vs Propofol Alone in Patients Undergoing Hysteroscopy: A Randomised Double-Blind Trial.

Authors: Qin Y; Department of Anaesthesiology, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, 200127, People's Republic of China.; Key Laboratory of Anesthesiology, Ministry of Education, Shanghai Jiao Tong University, Shanghai, People's Republic of China., Ye F; Department of Anaesthesiology, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, 200127, People's Republic of China.; Key Laboratory of Anesthesiology, Ministry of Education, Shanghai Jiao Tong University, Shanghai, People's Republic of China., Wang T; Department of Anaesthesiology, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, 200127, People's Republic of China.; Key Laboratory of Anesthesiology, Ministry of Education, Shanghai Jiao Tong University, Shanghai, People's Republic of China., Chen Y; Department of Anaesthesiology, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, 200127, People's Republic of China.; Key Laboratory of Anesthesiology, Ministry of Education, Shanghai Jiao Tong University, Shanghai, People's Republic of China., Zhang X; Department of Anaesthesiology, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, 200127, People's Republic of China., Qin Y; Department of Military Health Statistics, Naval Medical University, Shanghai, People's Republic of China., Gu X; Department of Anaesthesiology, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, 200127, People's Republic of China.; Key Laboratory of Anesthesiology, Ministry of Education, Shanghai Jiao Tong University, Shanghai, People's Republic of China., Yang L; Department of Anaesthesiology, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, 200127, People's Republic of China.; Key Laboratory of Anesthesiology, Ministry of Education, Shanghai Jiao Tong University, Shanghai, People's Republic of China., Zhu Z; Department of Anaesthesiology, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, 200127, People's Republic of China.; Key Laboratory of Anesthesiology, Ministry of Education, Shanghai Jiao Tong University, Shanghai, People's Republic of China., Xiao J; Department of Anaesthesiology, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, 200127, People's Republic of China.; Key Laboratory of Anesthesiology, Ministry of Education, Shanghai Jiao Tong University, Shanghai, People's Republic of China.

Source: Drug design, development and therapy [Drug Des Devel Ther] 2026 Sep 17; Vol. 20, pp. 645021. Date of Electronic Publication: 2026 Sep 17 (Print Publication: 2026).

Publication Type: Equivalence Trial; Journal Article; Randomized Controlled Trial

Journal Info: Publisher: Dove Press Limited Country of Publication: New Zealand NLM ID: 101475745 Publication Model: eCollection Cited Medium: Internet ISSN: 1177-8881 (Electronic) Linking ISSN: 11778881 NLM ISO Abbreviation: Drug Des Devel Ther Subsets: MEDLINE

MeSH Terms: Anesthetics, Intravenous*/administration & dosage , Apnea*/drug therapy , Apnea*/chemically induced , Etomidate*/administration & dosage , Etomidate*/pharmacology , Propofol*/administration & dosage , Propofol*/pharmacology , Hysteroscopy*, Adolescent ; Adult ; Female ; Humans ; Middle Aged ; Young Adult ; Double-Blind Method ; Aged

Impact of Cipepofol versus Propofol on Long-Term Cardiovascular Outcomes After TAVR: An Extended Follow-Up of a Randomized Trial.

Authors: Ni T; Department of Anesthesiology, The Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou, Zhejiang, People's Republic of China., Lv Y; Department of Anesthesiology, The Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou, Zhejiang, People's Republic of China., Zhou L; Department of Anesthesiology, The Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou, Zhejiang, People's Republic of China., Yu J; Department of Anesthesiology, The Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou, Zhejiang, People's Republic of China., Tao X; Department of Anesthesiology, The Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou, Zhejiang, People's Republic of China., Cao H; Department of Anesthesiology, The Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou, Zhejiang, People's Republic of China., Yao Y; Department of Anesthesiology, The Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou, Zhejiang, People's Republic of China., Yan M; Department of Anesthesiology, The Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou, Zhejiang, People's Republic of China.

Source: Drug design, development and therapy [Drug Des Devel Ther] 2026 Sep 17; Vol. 20, pp. 621481. Date of Electronic Publication: 2026 Sep 17 (Print Publication: 2026).

Publication Type: Journal Article; Randomized Controlled Trial; Comparative Study

Journal Info: Publisher: Dove Press Limited Country of Publication: New Zealand NLM ID: 101475745 Publication Model: eCollection Cited Medium: Internet ISSN: 1177-8881 (Electronic) Linking ISSN: 11778881 NLM ISO Abbreviation: Drug Des Devel Ther Subsets: MEDLINE

MeSH Terms: Propofol*/administration & dosage , Propofol*/adverse effects , Anesthetics, Intravenous*/administration & dosage , Transcatheter Aortic Valve Replacement*, Humans ; Female ; Follow-Up Studies ; Male ; Aged, 80 and over ; Aged ; Treatment Outcome ; Time Factors

Paraventricular Hypothalamic GLP-1R Neurons Mediate Propofol-Induced Suppression of Food Intake.

Authors: Liang J; Department of Endocrinology, Songjiang Research Institute, Songjiang Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, 201699‌ Shanghai, China.; Shanghai Key Laboratory of Emotions and Affective Disorders (LEAD), Shanghai Jiao Tong University School of Medicine, 201699‌ Shanghai, China., Yin M; Department of Endocrinology, Songjiang Research Institute, Songjiang Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, 201699‌ Shanghai, China.; Shanghai Key Laboratory of Emotions and Affective Disorders (LEAD), Shanghai Jiao Tong University School of Medicine, 201699‌ Shanghai, China., Su Y; Department of Endocrinology, Songjiang Research Institute, Songjiang Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, 201699‌ Shanghai, China.; Shanghai Key Laboratory of Emotions and Affective Disorders (LEAD), Shanghai Jiao Tong University School of Medicine, 201699‌ Shanghai, China., Zhang L; Department of Endocrinology, Songjiang Research Institute, Songjiang Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, 201699‌ Shanghai, China.; Shanghai Key Laboratory of Emotions and Affective Disorders (LEAD), Shanghai Jiao Tong University School of Medicine, 201699‌ Shanghai, China., Han Y; Department of Endocrinology, Songjiang Research Institute, Songjiang Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, 201699‌ Shanghai, China.; Shanghai Key Laboratory of Emotions and Affective Disorders (LEAD), Shanghai Jiao Tong University School of Medicine, 201699‌ Shanghai, China.

Source: Journal of integrative neuroscience [J Integr Neurosci] 2026 Sep 15; Vol. 25 (9), pp. 52398.

Publication Type: Journal Article

Journal Info: Publisher: IMR Press Country of Publication: Singapore NLM ID: 101156357 Publication Model: Print Cited Medium: Internet ISSN: 0219-6352 (Print) Linking ISSN: 02196352 NLM ISO Abbreviation: J Integr Neurosci Subsets: MEDLINE

MeSH Terms: Propofol*/pharmacology , Propofol*/administration & dosage , Neurons*/drug effects , Neurons*/metabolism , Paraventricular Hypothalamic Nucleus*/drug effects , Paraventricular Hypothalamic Nucleus*/metabolism , Eating*/drug effects , Glucagon-Like Peptide-1 Receptor*/metabolism , Glucagon-Like Peptide-1 Receptor*/drug effects , Anesthetics, Intravenous*/pharmacology , Anesthetics, Intravenous*/administration & dosage, Feeding Behavior/drug effects ; Animals ; Male ; Mice ; Mice, Inbred C57BL

Safety of Coadministration of Continuous Infusions of Propofol and Clevidipine: A Multi-Site Retrospective Analysis.

Authors: Warfield MN; Department of Pharmacy, Mayo Clinic, Rochester, Minnesota, USA., Cole KC; Division of Clinical Trials and Biostatistics, Mayo Clinic, Rochester, Minnesota, USA., Heybati K; Department of Internal Medicine, Mayo Clinic, Rochester, Minnesota, USA., Vollmer NJ; Department of Pharmacy, Mayo Clinic, Rochester, Minnesota, USA., Wieruszewski ED; Department of Pharmacy, Mayo Clinic, Rochester, Minnesota, USA.; Department of Emergency Medicine, Mayo Clinic, Rochester, Minnesota, USA., Yadav H; Division of Pulmonary and Critical Care Medicine, Mayo Clinic, Rochester, Minnesota, USA., Rabinstein AA; Department of Neurology, Mayo Clinic, Rochester, Minnesota, USA., Brown CS; Department of Pharmacy, Mayo Clinic, Rochester, Minnesota, USA.; Department of Emergency Medicine, Mayo Clinic, Rochester, Minnesota, USA.

Source: Pharmacotherapy [Pharmacotherapy] 2026 Sep; Vol. 46 (9), pp. e70196.

Publication Type: Journal Article; Multicenter Study

Journal Info: Publisher: Wiley-Blackwell Country of Publication: United States NLM ID: 8111305 Publication Model: Print Cited Medium: Internet ISSN: 1875-9114 (Electronic) Linking ISSN: 02770008 NLM ISO Abbreviation: Pharmacotherapy Subsets: MEDLINE

MeSH Terms: Propofol*/administration & dosage , Propofol*/adverse effects , Pancreatitis*/chemically induced , Pancreatitis*/epidemiology , Hypertriglyceridemia*/chemically induced , Hypertriglyceridemia*/epidemiology , Pyridines*/administration & dosage , Pyridines*/adverse effects, Triglycerides/blood ; Retrospective Studies ; Humans ; Male ; Female ; Risk Factors ; Middle Aged ; Infusions, Intravenous ; Aged

Effects of midazolam and propofol on EEG detection of epileptiform activity in patients with altered consciousness.

Authors: Guinchard M; Emergency Department, Lausanne University Hospital (CHUV), Lausanne, Switzerland., Rossetti AO; Department of Clinical Neurosciences, Lausanne University Hospital (CHUV), University of Lausanne, Lausanne, Switzerland., Schindler K; Sleep-Wake-Epilepsy-Center, Department of Neurology, Bern University Hospital (Inselspital), University of Bern, Bern, Switzerland., Rüegg S; Department of Neurology, University Hospital Basel and University of Basel, Basel, Switzerland., Alvarez V; Department of Neurology, Hôpital du Valais, Sion, Switzerland., Novy J; Department of Clinical Neurosciences, Lausanne University Hospital (CHUV), University of Lausanne, Lausanne, Switzerland. Electronic address: jan.novy@chuv.ch.

Source: Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology [Clin Neurophysiol] 2026 Sep; Vol. 189, pp. 2111941. Date of Electronic Publication: 2026 May 23.

Publication Type: Journal Article; Multicenter Study; Randomized Controlled Trial

Journal Info: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 100883319 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1872-8952 (Electronic) Linking ISSN: 13882457 NLM ISO Abbreviation: Clin Neurophysiol Subsets: MEDLINE

MeSH Terms: Propofol*/administration & dosage , Propofol*/therapeutic use , Propofol*/pharmacology , Electroencephalography*/drug effects , Electroencephalography*/methods , Midazolam*/administration & dosage , Midazolam*/therapeutic use , Midazolam*/pharmacology , Hypnotics and Sedatives*/therapeutic use , Hypnotics and Sedatives*/administration & dosage , Hypnotics and Sedatives*/pharmacology , Consciousness Disorders*/physiopathology , Consciousness Disorders*/drug therapy , Consciousness Disorders*/diagnosis , Epilepsy*/diagnosis , Epilepsy*/physiopathology , Epilepsy*/drug therapy, Consciousness/drug effects ; Humans ; Female ; Male ; Middle Aged ; Retrospective Studies ; Adult ; Aged

Breaking the Limitations of 'Milk': Research Progress on New Derivatives of Propofol.

Authors: Huang L; Department of Biomedical Engineering, College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan 430074, China., Xia Y; Jiangsu Key Laboratory of Marine Biological Resources and Environment, Jiangsu Key Laboratory of Marine Pharmaceutical Compound Screening, School of Pharmacy, Jiangsu Ocean University, Lianyungang 222005, China., Shi J; Jiangsu Key Laboratory of Marine Biological Resources and Environment, Jiangsu Key Laboratory of Marine Pharmaceutical Compound Screening, School of Pharmacy, Jiangsu Ocean University, Lianyungang 222005, China., Chen Y; Jiangsu Key Laboratory of Marine Biological Resources and Environment, Jiangsu Key Laboratory of Marine Pharmaceutical Compound Screening, School of Pharmacy, Jiangsu Ocean University, Lianyungang 222005, China., Hao C; Jiangsu Key Laboratory of Marine Biological Resources and Environment, Jiangsu Key Laboratory of Marine Pharmaceutical Compound Screening, School of Pharmacy, Jiangsu Ocean University, Lianyungang 222005, China.

Source: Molecules (Basel, Switzerland) [Molecules] 2026 Aug 31; Vol. 31 (17). Date of Electronic Publication: 2026 Aug 31.

Publication Type: Journal Article; Review

Journal Info: Publisher: MDPI Country of Publication: Switzerland NLM ID: 100964009 Publication Model: Electronic Cited Medium: Internet ISSN: 1420-3049 (Electronic) Linking ISSN: 14203049 NLM ISO Abbreviation: Molecules Subsets: MEDLINE

MeSH Terms: Propofol*/chemistry , Propofol*/analogs & derivatives , Propofol*/adverse effects , Propofol*/pharmacology , Propofol*/therapeutic use , Anesthetics, Intravenous*/chemistry , Anesthetics, Intravenous*/therapeutic use , Anesthetics, Intravenous*/adverse effects , Anesthetics, Intravenous*/pharmacology, Humans ; Animals ; Solubility

An Oxycodone-Based Conscious Analgesia Strategy with Supplemental Low-Dose Propofol Improves Safety in Elderly Obese Patients Undergoing Gastroscopy: A Prospective Randomized Controlled Trial.

Authors: Chang H; Department of Anesthesiology, The Third Xiangya Hospital, Central South University, Hunan, Changsha, 410013, People's Republic of China., Zhu X; Department of Anesthesiology, Xiangya Hospital, Central South University, Hunan, Changsha, 410008, People's Republic of China., Chen J; Department of Endocrinology, The First Hospital of Changsha, Changsha, Hunan, 410005, People's Republic of China., Chin M; Department of Anesthesiology, The Third Xiangya Hospital, Central South University, Hunan, Changsha, 410013, People's Republic of China., Zhan C; Department of Anesthesiology, Xiangya School of Medicine, Central South University, Hunan, Changsha, 410013, People's Republic of China., Zhang F; Department of Anesthesiology, The Third Xiangya Hospital, Central South University, Hunan, Changsha, 410013, People's Republic of China.

Source: Drug design, development and therapy [Drug Des Devel Ther] 2026 Aug 30; Vol. 20, pp. 625073. Date of Electronic Publication: 2026 Aug 30 (Print Publication: 2026).

Publication Type: Journal Article; Randomized Controlled Trial

Journal Info: Publisher: Dove Press Limited Country of Publication: New Zealand NLM ID: 101475745 Publication Model: eCollection Cited Medium: Internet ISSN: 1177-8881 (Electronic) Linking ISSN: 11778881 NLM ISO Abbreviation: Drug Des Devel Ther Subsets: MEDLINE

MeSH Terms: Analgesics, Opioid*/administration & dosage , Obesity*/drug therapy , Oxycodone*/administration & dosage , Oxycodone*/adverse effects , Propofol*/administration & dosage , Propofol*/adverse effects , Gastroscopy*, Aged ; Aged, 80 and over ; Female ; Humans ; Male ; Analgesia ; Dose-Response Relationship, Drug ; Geriatric Anesthesia ; Prospective Studies

Evaluating sedation efficacy and perioperative safety of fospropofol disodium versus propofol in elderly patients undergoing elective TURP: study protocol for a randomized controlled trial.

Authors: Sui H; Department of Anaesthesiology, The Second Hospital of Jiaxing, Second Affiliated Hospital of JiaXing University, 1518 Huancheng North Road, Nanhu District, Jiaxing City, Zhejiang Province, 314001, China., Wu T; Department of Anaesthesiology, The First Hospital of Jiaxing, Affiliated Hospital of JiaXing University, 1882 Zhonghuan South Road, Jiaxing City, Zhejiang Province, 314001, China., Gao L; Department of Anaesthesiology, The Second Hospital of Jiaxing, Second Affiliated Hospital of JiaXing University, 1518 Huancheng North Road, Nanhu District, Jiaxing City, Zhejiang Province, 314001, China., He Q; Department of Anaesthesiology, The Second Hospital of Jiaxing, Second Affiliated Hospital of JiaXing University, 1518 Huancheng North Road, Nanhu District, Jiaxing City, Zhejiang Province, 314001, China., Fan J; Department of Anesthesiology, Women and Children's Hospital of Jiaxing University, 2468 East Huancheng Road, Nanhu District, Jiaxing City, Zhejiang Province, 314001, China. 254602480@qq.com., Li Q; Department of Anaesthesiology, The Second Hospital of Jiaxing, Second Affiliated Hospital of JiaXing University, 1518 Huancheng North Road, Nanhu District, Jiaxing City, Zhejiang Province, 314001, China. Liqi77fyx@163.com.

Source: Trials [Trials] 2026 Aug 24; Vol. 27 (1). Date of Electronic Publication: 2026 Aug 24.

Publication Type: Journal Article; Clinical Trial Protocol

Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101263253 Publication Model: Electronic Cited Medium: Internet ISSN: 1745-6215 (Electronic) Linking ISSN: 17456215 NLM ISO Abbreviation: Trials Subsets: MEDLINE

MeSH Terms: Propofol*/analogs & derivatives , Propofol*/adverse effects , Propofol*/administration & dosage , Anesthetics, Intravenous*/adverse effects , Anesthetics, Intravenous*/administration & dosage , Transurethral Resection of Prostate*/adverse effects , Anesthesia, General*/methods , Anesthesia, General*/adverse effects , Hypnotics and Sedatives*/adverse effects , Hypnotics and Sedatives*/administration & dosage, Consciousness/drug effects ; Humans ; Male ; Aged ; Aged, 80 and over ; Elective Surgical Procedures ; Geriatric Anesthesia ; Treatment Outcome ; Randomized Controlled Trials as Topic ; Age Factors ; Time Factors ; China

Post-Intubation Hypotension After Titrated Induction with Ciprofol versus Propofol in Older Adults Undergoing Non-Cardiac Surgery: A Randomized Controlled Trial.

Authors: Bai H; Department of Anesthesia, The Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou, People's Republic of China.; Biomedical Innovation Center, The Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou, People's Republic of China., Guo J; Department of Anesthesia, The Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou, People's Republic of China.; Biomedical Innovation Center, The Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou, People's Republic of China., Li Y; Department of Anesthesia, The Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou, People's Republic of China.; Biomedical Innovation Center, The Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou, People's Republic of China., Zhang S; Department of Anesthesia, The Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou, People's Republic of China., Chen S; Department of Anesthesia, The Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou, People's Republic of China., Wang Z; Department of Anesthesia, The Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou, People's Republic of China., Lu K; Department of Anesthesia, The Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou, People's Republic of China., Zhang L; Department of Anesthesia, The Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou, People's Republic of China.; Biomedical Innovation Center, The Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou, People's Republic of China., Zhong F; Department of Anesthesia, The Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou, People's Republic of China., Gong R; Department of Anesthesia, The Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou, People's Republic of China., Li J; Department of Anesthesia, The Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou, People's Republic of China., Han J; Department of Anesthesia, The Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou, People's Republic of China., Song X; Department of Anesthesia, The Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou, People's Republic of China., Jin S; Department of Anesthesia, The Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou, People's Republic of China.; Biomedical Innovation Center, The Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou, People's Republic of China.

Source: Clinical interventions in aging [Clin Interv Aging] 2026 Aug 22; Vol. 21, pp. 609412. Date of Electronic Publication: 2026 Aug 22 (Print Publication: 2026).

Publication Type: Journal Article; Randomized Controlled Trial; Comparative Study

Journal Info: Publisher: Dove Medical Press Country of Publication: New Zealand NLM ID: 101273480 Publication Model: eCollection Cited Medium: Internet ISSN: 1178-1998 (Electronic) Linking ISSN: 11769092 NLM ISO Abbreviation: Clin Interv Aging Subsets: MEDLINE

MeSH Terms: Propofol*/adverse effects , Propofol*/administration & dosage , Hypotension*/chemically induced , Hypotension*/etiology , Anesthetics, Intravenous*/adverse effects , Anesthetics, Intravenous*/administration & dosage , Intubation, Intratracheal*/adverse effects, Norepinephrine/administration & dosage ; Humans ; Aged ; Female ; Double-Blind Method ; Male ; Prospective Studies ; Aged, 80 and over ; Geriatric Anesthesia ; Cyclopropanes

Effect of Remimazolam and Propofol on Intraoperative Blood Pressure Variability in Patients Undergoing Endovascular Embolization of Intracranial Aneurysms.

Authors: Duan Y; Department of Anesthesiology, Shanxi Bethune Hospital, Shanxi Academy of Medical Sciences, Third Hospital of Shanxi Medical University, Tongji Shanxi Hospital, Taiyuan, Shanxi, People's Republic of China., He J; Department of Anesthesiology, Shanxi Bethune Hospital, Shanxi Academy of Medical Sciences, Third Hospital of Shanxi Medical University, Tongji Shanxi Hospital, Taiyuan, Shanxi, People's Republic of China., Han C; Department of Anesthesiology, Shanxi Bethune Hospital, Shanxi Academy of Medical Sciences, Third Hospital of Shanxi Medical University, Tongji Shanxi Hospital, Taiyuan, Shanxi, People's Republic of China., Yang W; Department of Anesthesiology, Shanxi Bethune Hospital, Shanxi Academy of Medical Sciences, Third Hospital of Shanxi Medical University, Tongji Shanxi Hospital, Taiyuan, Shanxi, People's Republic of China., Wang Z; Department of Anesthesiology, Shanxi Bethune Hospital, Shanxi Academy of Medical Sciences, Third Hospital of Shanxi Medical University, Tongji Shanxi Hospital, Taiyuan, Shanxi, People's Republic of China., Zhou X; Department of Anesthesiology, The First Hospital of Hebei Medical University, Shijiazhuang, Hebei, People's Republic of China., Yu J; Department of Anesthesiology, Shanxi Bethune Hospital, Shanxi Academy of Medical Sciences, Third Hospital of Shanxi Medical University, Tongji Shanxi Hospital, Taiyuan, Shanxi, People's Republic of China.

Source: Drug design, development and therapy [Drug Des Devel Ther] 2026 Aug 21; Vol. 20, pp. 630786. Date of Electronic Publication: 2026 Aug 21 (Print Publication: 2026).

Publication Type: Journal Article; Randomized Controlled Trial

Journal Info: Publisher: Dove Press Limited Country of Publication: New Zealand NLM ID: 101475745 Publication Model: eCollection Cited Medium: Internet ISSN: 1177-8881 (Electronic) Linking ISSN: 11778881 NLM ISO Abbreviation: Drug Des Devel Ther Subsets: MEDLINE

MeSH Terms: Blood Pressure*/drug effects , Intracranial Aneurysm*/drug therapy , Intracranial Aneurysm*/therapy , Intracranial Aneurysm*/surgery , Intracranial Aneurysm*/physiopathology , Propofol*/pharmacology , Propofol*/administration & dosage , Benzodiazepines*/administration & dosage , Benzodiazepines*/pharmacology , Embolization, Therapeutic* , Endovascular Procedures*, Adult ; Aged ; Female ; Humans ; Male ; Middle Aged ; Prospective Studies