Myokine Levels in Relation to Bone Markers and Adipokines in Children with Prader-Willi Syndrome During Growth Hormone Therapy and Dietary Intervention.

Authors: Gajewska J; Department of Screening Tests and Metabolic Diagnostics, Institute of Mother and Child, 01-211 Warsaw, Poland., Chełchowska M; Department of Screening Tests and Metabolic Diagnostics, Institute of Mother and Child, 01-211 Warsaw, Poland., Szamotulska K; Department of Epidemiology and Biostatistics, Institute of Mother and Child, 01-211 Warsaw, Poland., Strucińska M; Department of Nutrition, Institute of Mother and Child, 01-211 Warsaw, Poland., Klemarczyk W; Department of Nutrition, Institute of Mother and Child, 01-211 Warsaw, Poland., Ambroszkiewicz J; Department of Screening Tests and Metabolic Diagnostics, Institute of Mother and Child, 01-211 Warsaw, Poland.

Source: International journal of molecular sciences [Int J Mol Sci] 2025 Nov 07; Vol. 26 (22). Date of Electronic Publication: 2025 Nov 07.

Publication Type: Journal Article

Journal Info: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067 (Electronic) Linking ISSN: 14220067 NLM ISO Abbreviation: Int J Mol Sci Subsets: MEDLINE

MeSH Terms: Prader-Willi Syndrome*/blood , Prader-Willi Syndrome*/diet therapy , Prader-Willi Syndrome*/drug therapy , Prader-Willi Syndrome*/metabolism , Adipokines*/blood , Human Growth Hormone*/therapeutic use , Bone and Bones*/metabolism, Humans ; Male ; Child ; Female ; Biomarkers/blood ; Adolescent ; Child, Preschool ; Myostatin/blood ; Case-Control Studies ; Osteocalcin/blood ; Body Composition ; Myokines

A questionnaire-based survey on hyperphagia in individuals with Prader-Willi syndrome in Japan.

Authors: Tachibana M; Research Committee on Clinical Management of Growth Disorders and Differences of Sex Development, Research on Measures for Intractable Diseases, Health and Labour Sciences Research Grants, Tokyo, Japan.; Department of Pediatrics, Osaka University, Suita 565-0871, Japan., Oto Y; Research Committee on Clinical Management of Growth Disorders and Differences of Sex Development, Research on Measures for Intractable Diseases, Health and Labour Sciences Research Grants, Tokyo, Japan.; Department of Pediatrics, Dokkyo Medical University Saitama Medical Center, Koshigaya 343-8555, Japan., Kashimada K; Research Committee on Clinical Management of Growth Disorders and Differences of Sex Development, Research on Measures for Intractable Diseases, Health and Labour Sciences Research Grants, Tokyo, Japan.; Division of Endocrinology and Metabolism, National Center for Child Health and Development, Tokyo 157-8535, Japan., Ishii T; Research Committee on Clinical Management of Growth Disorders and Differences of Sex Development, Research on Measures for Intractable Diseases, Health and Labour Sciences Research Grants, Tokyo, Japan.; Department of Pediatrics, Keio University School of Medicine, Tokyo 160-8582, Japan., Takahashi Y; Research Committee on Clinical Management of Growth Disorders and Differences of Sex Development, Research on Measures for Intractable Diseases, Health and Labour Sciences Research Grants, Tokyo, Japan.; Department of Diabetes and Endocrinology, Nara Medical University, Kashihara 634-8521, Japan., Muroya K; Research Committee on Clinical Management of Growth Disorders and Differences of Sex Development, Research on Measures for Intractable Diseases, Health and Labour Sciences Research Grants, Tokyo, Japan.; Department of Endocrinology and Metabolism, Kanagawa Children's Medical Center, Yokohama 232-8555, Japan., Aoki Y; Research Committee on Clinical Management of Growth Disorders and Differences of Sex Development, Research on Measures for Intractable Diseases, Health and Labour Sciences Research Grants, Tokyo, Japan.; Department of Medical Genetics, Tohoku University School of Medicine, Sendai 980-8574, Japan., Kurosawa K; Research Committee on Clinical Management of Growth Disorders and Differences of Sex Development, Research on Measures for Intractable Diseases, Health and Labour Sciences Research Grants, Tokyo, Japan.; Division of Medical Genetics, Kanagawa Children's Medical Center, Yokohama 232-8555, Japan., Ogata T; Research Committee on Clinical Management of Growth Disorders and Differences of Sex Development, Research on Measures for Intractable Diseases, Health and Labour Sciences Research Grants, Tokyo, Japan.; Department of Pediatrics, Hamamatsu Medical Center, Hamamatsu 431-3192, Japan., Kawai M; Research Committee on Clinical Management of Growth Disorders and Differences of Sex Development, Research on Measures for Intractable Diseases, Health and Labour Sciences Research Grants, Tokyo, Japan.; Department of Gastroenterology, Nutrition, and Endocrinology, Osaka Women's and Children's Hospital, Izumi 594-1101, Japan.; Department of Molecular Genetics and Endocrinology, Research Institute, Osaka Women's and Children's Hospital, Izumi 594-1101, Japan.

Source: Endocrine journal [Endocr J] 2025 Nov 04; Vol. 72 (11), pp. 1217-1225. Date of Electronic Publication: 2025 Jul 23.

Publication Type: Journal Article

Journal Info: Publisher: Japan Endocrine Society Country of Publication: Japan NLM ID: 9313485 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1348-4540 (Electronic) Linking ISSN: 09188959 NLM ISO Abbreviation: Endocr J Subsets: MEDLINE

MeSH Terms: Prader-Willi Syndrome*/complications , Prader-Willi Syndrome*/epidemiology , Prader-Willi Syndrome*/genetics , Hyperphagia*/epidemiology , Hyperphagia*/etiology , Hyperphagia*/diagnosis, Humans ; Japan/epidemiology ; Adult ; Male ; Female ; Middle Aged ; Adolescent ; Surveys and Questionnaires ; Young Adult ; Child ; Child, Preschool ; Infant ; Obesity/epidemiology ; Obesity/etiology ; Infant, Newborn

Long-term growth hormone effects in Prader-Willi syndrome: A systematic review and meta-analysis.

Authors: Almutadares MN; From the Department of Genetic Medicine (Almutadares), Faculty of Medicine, King Abdulaziz University; from the Department of Pediatrics (Gazzaz, Alyahyawi, Hothan, Bukhari, A. Mazi), Faculty of Medicine, King Abdulaziz University; from the Medical Laboratory Sciences (Alrayes), Faculty of Applied Medical Sciences, King Abdulaziz University; from Princess Al-Jawhara Center of Excellence in Research of Hereditary Disorders (Alrayes); from the Primary Health Care (E. Mazi), King Abdullah Complex Center, Jeddah Second Health Cluster, Ministry of Health; from the Department of Emergency Medicine (Mansouri), Faculty of Medicine, King Abdulaziz University; and from the Faculty of Medicine in Rabigh (Hamadallah), King Abdulaziz University Jeddah, Kingdom of Saudi Arabia., Gazzaz NM; From the Department of Genetic Medicine (Almutadares), Faculty of Medicine, King Abdulaziz University; from the Department of Pediatrics (Gazzaz, Alyahyawi, Hothan, Bukhari, A. Mazi), Faculty of Medicine, King Abdulaziz University; from the Medical Laboratory Sciences (Alrayes), Faculty of Applied Medical Sciences, King Abdulaziz University; from Princess Al-Jawhara Center of Excellence in Research of Hereditary Disorders (Alrayes); from the Primary Health Care (E. Mazi), King Abdullah Complex Center, Jeddah Second Health Cluster, Ministry of Health; from the Department of Emergency Medicine (Mansouri), Faculty of Medicine, King Abdulaziz University; and from the Faculty of Medicine in Rabigh (Hamadallah), King Abdulaziz University Jeddah, Kingdom of Saudi Arabia., Alyahyawi NY; From the Department of Genetic Medicine (Almutadares), Faculty of Medicine, King Abdulaziz University; from the Department of Pediatrics (Gazzaz, Alyahyawi, Hothan, Bukhari, A. Mazi), Faculty of Medicine, King Abdulaziz University; from the Medical Laboratory Sciences (Alrayes), Faculty of Applied Medical Sciences, King Abdulaziz University; from Princess Al-Jawhara Center of Excellence in Research of Hereditary Disorders (Alrayes); from the Primary Health Care (E. Mazi), King Abdullah Complex Center, Jeddah Second Health Cluster, Ministry of Health; from the Department of Emergency Medicine (Mansouri), Faculty of Medicine, King Abdulaziz University; and from the Faculty of Medicine in Rabigh (Hamadallah), King Abdulaziz University Jeddah, Kingdom of Saudi Arabia., Alrayes NM; From the Department of Genetic Medicine (Almutadares), Faculty of Medicine, King Abdulaziz University; from the Department of Pediatrics (Gazzaz, Alyahyawi, Hothan, Bukhari, A. Mazi), Faculty of Medicine, King Abdulaziz University; from the Medical Laboratory Sciences (Alrayes), Faculty of Applied Medical Sciences, King Abdulaziz University; from Princess Al-Jawhara Center of Excellence in Research of Hereditary Disorders (Alrayes); from the Primary Health Care (E. Mazi), King Abdullah Complex Center, Jeddah Second Health Cluster, Ministry of Health; from the Department of Emergency Medicine (Mansouri), Faculty of Medicine, King Abdulaziz University; and from the Faculty of Medicine in Rabigh (Hamadallah), King Abdulaziz University Jeddah, Kingdom of Saudi Arabia., Mazi EA; From the Department of Genetic Medicine (Almutadares), Faculty of Medicine, King Abdulaziz University; from the Department of Pediatrics (Gazzaz, Alyahyawi, Hothan, Bukhari, A. Mazi), Faculty of Medicine, King Abdulaziz University; from the Medical Laboratory Sciences (Alrayes), Faculty of Applied Medical Sciences, King Abdulaziz University; from Princess Al-Jawhara Center of Excellence in Research of Hereditary Disorders (Alrayes); from the Primary Health Care (E. Mazi), King Abdullah Complex Center, Jeddah Second Health Cluster, Ministry of Health; from the Department of Emergency Medicine (Mansouri), Faculty of Medicine, King Abdulaziz University; and from the Faculty of Medicine in Rabigh (Hamadallah), King Abdulaziz University Jeddah, Kingdom of Saudi Arabia., Mansouri FF; From the Department of Genetic Medicine (Almutadares), Faculty of Medicine, King Abdulaziz University; from the Department of Pediatrics (Gazzaz, Alyahyawi, Hothan, Bukhari, A. Mazi), Faculty of Medicine, King Abdulaziz University; from the Medical Laboratory Sciences (Alrayes), Faculty of Applied Medical Sciences, King Abdulaziz University; from Princess Al-Jawhara Center of Excellence in Research of Hereditary Disorders (Alrayes); from the Primary Health Care (E. Mazi), King Abdullah Complex Center, Jeddah Second Health Cluster, Ministry of Health; from the Department of Emergency Medicine (Mansouri), Faculty of Medicine, King Abdulaziz University; and from the Faculty of Medicine in Rabigh (Hamadallah), King Abdulaziz University Jeddah, Kingdom of Saudi Arabia., Hothan KA; From the Department of Genetic Medicine (Almutadares), Faculty of Medicine, King Abdulaziz University; from the Department of Pediatrics (Gazzaz, Alyahyawi, Hothan, Bukhari, A. Mazi), Faculty of Medicine, King Abdulaziz University; from the Medical Laboratory Sciences (Alrayes), Faculty of Applied Medical Sciences, King Abdulaziz University; from Princess Al-Jawhara Center of Excellence in Research of Hereditary Disorders (Alrayes); from the Primary Health Care (E. Mazi), King Abdullah Complex Center, Jeddah Second Health Cluster, Ministry of Health; from the Department of Emergency Medicine (Mansouri), Faculty of Medicine, King Abdulaziz University; and from the Faculty of Medicine in Rabigh (Hamadallah), King Abdulaziz University Jeddah, Kingdom of Saudi Arabia., Hamadallah HA; From the Department of Genetic Medicine (Almutadares), Faculty of Medicine, King Abdulaziz University; from the Department of Pediatrics (Gazzaz, Alyahyawi, Hothan, Bukhari, A. Mazi), Faculty of Medicine, King Abdulaziz University; from the Medical Laboratory Sciences (Alrayes), Faculty of Applied Medical Sciences, King Abdulaziz University; from Princess Al-Jawhara Center of Excellence in Research of Hereditary Disorders (Alrayes); from the Primary Health Care (E. Mazi), King Abdullah Complex Center, Jeddah Second Health Cluster, Ministry of Health; from the Department of Emergency Medicine (Mansouri), Faculty of Medicine, King Abdulaziz University; and from the Faculty of Medicine in Rabigh (Hamadallah), King Abdulaziz University Jeddah, Kingdom of Saudi Arabia., Bukhari EM; From the Department of Genetic Medicine (Almutadares), Faculty of Medicine, King Abdulaziz University; from the Department of Pediatrics (Gazzaz, Alyahyawi, Hothan, Bukhari, A. Mazi), Faculty of Medicine, King Abdulaziz University; from the Medical Laboratory Sciences (Alrayes), Faculty of Applied Medical Sciences, King Abdulaziz University; from Princess Al-Jawhara Center of Excellence in Research of Hereditary Disorders (Alrayes); from the Primary Health Care (E. Mazi), King Abdullah Complex Center, Jeddah Second Health Cluster, Ministry of Health; from the Department of Emergency Medicine (Mansouri), Faculty of Medicine, King Abdulaziz University; and from the Faculty of Medicine in Rabigh (Hamadallah), King Abdulaziz University Jeddah, Kingdom of Saudi Arabia., Mazi AA; From the Department of Genetic Medicine (Almutadares), Faculty of Medicine, King Abdulaziz University; from the Department of Pediatrics (Gazzaz, Alyahyawi, Hothan, Bukhari, A. Mazi), Faculty of Medicine, King Abdulaziz University; from the Medical Laboratory Sciences (Alrayes), Faculty of Applied Medical Sciences, King Abdulaziz University; from Princess Al-Jawhara Center of Excellence in Research of Hereditary Disorders (Alrayes); from the Primary Health Care (E. Mazi), King Abdullah Complex Center, Jeddah Second Health Cluster, Ministry of Health; from the Department of Emergency Medicine (Mansouri), Faculty of Medicine, King Abdulaziz University; and from the Faculty of Medicine in Rabigh (Hamadallah), King Abdulaziz University Jeddah, Kingdom of Saudi Arabia.

Source: Saudi medical journal [Saudi Med J] 2025 Nov; Vol. 46 (11), pp. 1257-1275.

Publication Type: Journal Article; Systematic Review; Meta-Analysis

Journal Info: Publisher: Medical Services Department, Saudi Arabian Armed Forces, Ministry Of Defence And Aviation Country of Publication: Saudi Arabia NLM ID: 7909441 Publication Model: Print Cited Medium: Internet ISSN: 1658-3175 (Electronic) Linking ISSN: 03795284 NLM ISO Abbreviation: Saudi Med J Subsets: MEDLINE

MeSH Terms: Prader-Willi Syndrome*/drug therapy , Prader-Willi Syndrome*/mortality , Human Growth Hormone*/therapeutic use, Humans ; Insulin-Like Growth Factor I/metabolism ; Body Mass Index ; Body Height/drug effects ; Blood Glucose/metabolism ; Cholesterol, LDL/blood

Systematic Review of Intervention Programs Designed to Improve the Socioemotional Skills of Children and Adolescents With Prader-Willi Syndrome.

Authors: Perosanz A; Ane Perosanz and Oscar Martínez, University of Deusto, Bilbao Biscay, Spain; Néstor Roselli, Pontifical Catholic University of Argentina, Autonomous City of Buenos Aires, Argentina; Paula Pérez-Núñez, Samuel Anguiano, and Juan Francisco López-Paz, University of Deusto, Bilbao Biscay, Spain., Martínez O; Ane Perosanz and Oscar Martínez, University of Deusto, Bilbao Biscay, Spain; Néstor Roselli, Pontifical Catholic University of Argentina, Autonomous City of Buenos Aires, Argentina; Paula Pérez-Núñez, Samuel Anguiano, and Juan Francisco López-Paz, University of Deusto, Bilbao Biscay, Spain., Roselli N; Ane Perosanz and Oscar Martínez, University of Deusto, Bilbao Biscay, Spain; Néstor Roselli, Pontifical Catholic University of Argentina, Autonomous City of Buenos Aires, Argentina; Paula Pérez-Núñez, Samuel Anguiano, and Juan Francisco López-Paz, University of Deusto, Bilbao Biscay, Spain., Pérez-Núñez P; Ane Perosanz and Oscar Martínez, University of Deusto, Bilbao Biscay, Spain; Néstor Roselli, Pontifical Catholic University of Argentina, Autonomous City of Buenos Aires, Argentina; Paula Pérez-Núñez, Samuel Anguiano, and Juan Francisco López-Paz, University of Deusto, Bilbao Biscay, Spain., Anguiano S; Ane Perosanz and Oscar Martínez, University of Deusto, Bilbao Biscay, Spain; Néstor Roselli, Pontifical Catholic University of Argentina, Autonomous City of Buenos Aires, Argentina; Paula Pérez-Núñez, Samuel Anguiano, and Juan Francisco López-Paz, University of Deusto, Bilbao Biscay, Spain., López-Paz JF; Ane Perosanz and Oscar Martínez, University of Deusto, Bilbao Biscay, Spain; Néstor Roselli, Pontifical Catholic University of Argentina, Autonomous City of Buenos Aires, Argentina; Paula Pérez-Núñez, Samuel Anguiano, and Juan Francisco López-Paz, University of Deusto, Bilbao Biscay, Spain.

Source: American journal on intellectual and developmental disabilities [Am J Intellect Dev Disabil] 2025 Nov 01; Vol. 130 (6), pp. 475-489.

Publication Type: Journal Article; Systematic Review

Journal Info: Publisher: American Association on Intellectual and Developmental Disabilities Country of Publication: United States NLM ID: 101492916 Publication Model: Print Cited Medium: Internet ISSN: 1944-7558 (Electronic) Linking ISSN: 19447558 NLM ISO Abbreviation: Am J Intellect Dev Disabil Subsets: MEDLINE

MeSH Terms: Prader-Willi Syndrome*/psychology , Prader-Willi Syndrome*/rehabilitation , Social Skills*, Humans ; Child ; Adolescent ; Telemedicine

Food responsiveness, addiction, and hyperphagia in Prader-Willi syndrome: a cross-sectional study of 210 Chinese patients.

Authors: Hu CX; Department of Endocrinology, Children's Hospital, Zhejiang University School of Medicine, National Clinical Research Center for Child Health, Hangzhou, Zhejiang, China., Xia FL; Department of Endocrinology, Children's Hospital, Zhejiang University School of Medicine, National Clinical Research Center for Child Health, Hangzhou, Zhejiang, China., Qin YF; Department of Endocrinology, Children's Hospital, Zhejiang University School of Medicine, National Clinical Research Center for Child Health, Hangzhou, Zhejiang, China., Chao YQ; Department of Endocrinology, Children's Hospital, Zhejiang University School of Medicine, National Clinical Research Center for Child Health, Hangzhou, Zhejiang, China., Ruan YL; Department of Endocrinology, Children's Hospital, Zhejiang University School of Medicine, National Clinical Research Center for Child Health, Hangzhou, Zhejiang, China., Li JW; Department of Endocrinology, Children's Hospital, Zhejiang University School of Medicine, National Clinical Research Center for Child Health, Hangzhou, Zhejiang, China., Dong GP; Department of Endocrinology, Children's Hospital, Zhejiang University School of Medicine, National Clinical Research Center for Child Health, Hangzhou, Zhejiang, China., Zou CC; Department of Endocrinology, Children's Hospital, Zhejiang University School of Medicine, National Clinical Research Center for Child Health, Hangzhou, Zhejiang, China.

Source: Frontiers in endocrinology [Front Endocrinol (Lausanne)] 2025 Oct 23; Vol. 16, pp. 1665040. Date of Electronic Publication: 2025 Oct 23 (Print Publication: 2025).

Publication Type: Journal Article

Journal Info: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101555782 Publication Model: eCollection Cited Medium: Print ISSN: 1664-2392 (Print) Linking ISSN: 16642392 NLM ISO Abbreviation: Front Endocrinol (Lausanne) Subsets: MEDLINE

MeSH Terms: Prader-Willi Syndrome*/complications , Prader-Willi Syndrome*/psychology , Prader-Willi Syndrome*/physiopathology , Prader-Willi Syndrome*/epidemiology , Prader-Willi Syndrome*/drug therapy , Hyperphagia*/etiology , Hyperphagia*/epidemiology , Food Addiction*/etiology , Food Addiction*/epidemiology , Food Addiction*/psychology , Feeding Behavior*/physiology, Humans ; Male ; Female ; Cross-Sectional Studies ; Child ; Adolescent ; China/epidemiology ; Surveys and Questionnaires ; Child, Preschool ; East Asian People

Fiber Intervention Study in Prader-Willi Syndrome: Insights into Metabolic and Microbiota Shifts.

Authors: Tan Q; Department of Pediatrics, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, AB, Canada T6G 2B7., Peng Y; Microbiota I-Center (MagIC), Hong Kong SAR, 999077, China.; JC School of Public Health and Primary Care, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong SAR, 999077, China.; Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong, Hong Kong SAR, 999077, China., Deehan EC; Department of Food Science and Technology, University of Nebraska, Lincoln, NE 68588, USA.; Nebraska Food for Health Center, Food Science & Technology, Lincoln, NE 68588, USA., Vieira FT; Department of Pediatrics, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, AB, Canada T6G 2B7., Ho BWP; Microbiota I-Center (MagIC), Hong Kong SAR, 999077, China., Afhami S; Cumming School of Medicine, University of Calgary, Calgary, AB, Canada T2N 1N4., Wine E; Department of Pediatrics, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, AB, Canada T6G 2B7., Madsen KL; Department of Medicine, University of Alberta, Edmonton, AB, Canada T6G 2B7., Field CJ; Department of Agricultural, Food and Nutritional Science, University of Alberta, Edmonton, AB, Canada T6G 2P5., Pakseresht M; Department of Agricultural, Food and Nutritional Science, University of Alberta, Edmonton, AB, Canada T6G 2P5., Ilkayeva O; Duke Molecular Physiology Institute and Sarah W. Stedman Nutrition and Metabolism Center, Duke University School of Medicine, Durham, NC 27710, USA.; Department of Medicine, Division of Endocrinology, Metabolism, and Nutrition, Duke University School of Medicine, Durham, NC 27710, USA., Newgard CB; Duke Molecular Physiology Institute and Sarah W. Stedman Nutrition and Metabolism Center, Duke University School of Medicine, Durham, NC 27710, USA.; Department of Medicine, Division of Endocrinology, Metabolism, and Nutrition, Duke University School of Medicine, Durham, NC 27710, USA.; Department of Pharmacology and Cancer Biology, Duke University Medical Center, Durham, NC 27710, USA., Walter J; APC Microbiome Ireland, University College Cork, Cork T12 K8AF, County Cork, Ireland.; School of Microbiology, University College Cork, Cork T12 K8AF, County Cork, Ireland.; Department of Medicine, University College Cork, Cork T12 K8AF, County Cork, Ireland., Tun HM; Microbiota I-Center (MagIC), Hong Kong SAR, 999077, China.; JC School of Public Health and Primary Care, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong SAR, 999077, China.; Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong, Hong Kong SAR, 999077, China., Haqq AM; Department of Pediatrics, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, AB, Canada T6G 2B7.; Department of Agricultural, Food and Nutritional Science, University of Alberta, Edmonton, AB, Canada T6G 2P5.

Source: The Journal of clinical endocrinology and metabolism [J Clin Endocrinol Metab] 2025 Oct 16; Vol. 110 (11), pp. 3120-3132.

Publication Type: Journal Article

Journal Info: Publisher: Oxford University Press Country of Publication: United States NLM ID: 0375362 Publication Model: Print Cited Medium: Internet ISSN: 1945-7197 (Electronic) Linking ISSN: 0021972X NLM ISO Abbreviation: J Clin Endocrinol Metab Subsets: MEDLINE

MeSH Terms: Prader-Willi Syndrome*/microbiology , Prader-Willi Syndrome*/metabolism , Prader-Willi Syndrome*/diet therapy , Gastrointestinal Microbiome*/physiology , Gastrointestinal Microbiome*/drug effects , Dietary Fiber*/administration & dosage , Hyperphagia*/diet therapy , Hyperphagia*/metabolism , Hyperphagia*/microbiology , Hyperphagia*/etiology, Humans ; Female ; Male ; Adolescent ; Feces/microbiology ; Child ; Young Adult ; Adult ; Biomarkers/analysis

High Rates of Dysphagia and Silent Aspiration in Infants With Prader-Willi Syndrome.

Authors: Roy SM; Cook Children's Medical Center, Fort Worth, Texas, USA., Trejo A; Cook Children's Medical Center, Fort Worth, Texas, USA., McReynolds J; Cook Children's Medical Center, Fort Worth, Texas, USA., Fagerman A; Cook Children's Medical Center, Fort Worth, Texas, USA., Johnson YR; Cook Children's Medical Center, Fort Worth, Texas, USA.; Texas Christian University Burnett School of Medicine, Fort Worth, Texas, USA., Neblett A; Cook Children's Medical Center, Fort Worth, Texas, USA., Shaheed K; Cook Children's Medical Center, Fort Worth, Texas, USA., Taylor K; Cook Children's Medical Center, Fort Worth, Texas, USA.; University of North Texas Health Science Center, Fort Worth, Texas, USA.

Source: American journal of medical genetics. Part A [Am J Med Genet A] 2025 Oct; Vol. 197 (10), pp. e64121. Date of Electronic Publication: 2025 May 23.

Publication Type: Journal Article

Journal Info: Publisher: Wiley-Blackwell Country of Publication: United States NLM ID: 101235741 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1552-4833 (Electronic) Linking ISSN: 15524825 NLM ISO Abbreviation: Am J Med Genet A Subsets: MEDLINE

MeSH Terms: Prader-Willi Syndrome*/complications , Prader-Willi Syndrome*/physiopathology , Prader-Willi Syndrome*/epidemiology , Deglutition Disorders*/epidemiology , Deglutition Disorders*/physiopathology , Deglutition Disorders*/etiology , Deglutition Disorders*/diagnosis , Deglutition Disorders*/complications , Respiratory Aspiration*/epidemiology , Respiratory Aspiration*/physiopathology, Humans ; Male ; Infant ; Female ; Fluoroscopy ; Deglutition ; Risk Factors ; Infant, Newborn ; Prevalence

Relationship between body mass index and nutritional status across genetic subtypes of Prader-Willi syndrome.

Authors: Ceccomancini R; Department of Nutrition, Fundación SPINE, Buenos Aires, Argentina., Mendiola D; Department of Clinical Research, Fundación SPINE, Buenos Aires, Argentina., Nunes-Campos L; Department of Clinical Research, Fundación SPINE, Buenos Aires, Argentina., Stegmann J; Department of Internal Medicine, Fundación SPINE, Buenos Aires, Argentina. Electronic address: coordinacioninvestigacion@spine.org.ar.

Source: Clinical nutrition ESPEN [Clin Nutr ESPEN] 2025 Oct; Vol. 69, pp. 477-481. Date of Electronic Publication: 2025 Aug 07.

Publication Type: Journal Article

Journal Info: Publisher: Elsevier Ltd Country of Publication: England NLM ID: 101654592 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2405-4577 (Electronic) Linking ISSN: 24054577 NLM ISO Abbreviation: Clin Nutr ESPEN Subsets: MEDLINE

MeSH Terms: Prader-Willi Syndrome*/genetics , Prader-Willi Syndrome*/physiopathology , Body Mass Index* , Nutritional Status*, Humans ; Male ; Female ; Cross-Sectional Studies ; Retrospective Studies ; Young Adult ; Adolescent ; Adult ; Child ; Nutrition Assessment ; Genotype

Development of disease-specific growth charts for Argentine Prader-Willi syndrome without growth hormone treatment.

Authors: Caino S; Growth and Development Department, Hospital de Pediatría J.P. Garrahan, Buenos Aires, Argentina., Caminiti C; Department of Nutrition, Hospital de Pediatría J.P. Garrahan, Buenos Aires, Argentina., Rabosto Moleón R; Growth and Development Department, Hospital de Pediatría J.P. Garrahan, Buenos Aires, Argentina., Krochik G; Department of Nutrition, Hospital de Pediatría J.P. Garrahan, Buenos Aires, Argentina., Del Pino M; Growth and Development Department, Hospital de Pediatría J.P. Garrahan, Buenos Aires, Argentina.

Source: Annals of human biology [Ann Hum Biol] 2025 Dec; Vol. 52 (1), pp. 2534345. Date of Electronic Publication: 2025 Sep 04.

Publication Type: Journal Article

Journal Info: Publisher: Taylor & Francis Country of Publication: England NLM ID: 0404024 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1464-5033 (Electronic) Linking ISSN: 03014460 NLM ISO Abbreviation: Ann Hum Biol Subsets: MEDLINE

MeSH Terms: Prader-Willi Syndrome*/physiopathology , Growth Charts* , Body Height*, Humans ; Male ; Child ; Female ; Child, Preschool ; Infant ; Adolescent ; Young Adult ; Argentina ; Infant, Newborn

Sex Hormone Replacement Therapy and Bleeding Patterns among Adolescents and Young Adult Females with Prader-Willi Syndrome.

Authors: Friedman JC; University of Colorado Department of Obstetrics and Gynecology, Section of Pediatric and Adolescent Gynecology, Aurora, Colorado. Electronic address: juliecfriedman@gmail.com., Hutchens K; University of Tennessee Knoxville, College of Law, Appalachian Justice Research Center, Knoxville, Tennessee., Starkman H; University of Toronto Department of Obstetrics and Gynaecology, Toronto, Ontario, Canada., Beaty LE; Department of Biostatistics and Informatics, Colorado School of Public Health, Aurora, Colorado., Sammel MD; Department of Biostatistics and Informatics, Colorado School of Public Health, Aurora, Colorado., Finn E; Division of Endocrinology, University of Colorado Department of Medicine, Aurora, Colorado; Department of Pediatrics, Section of Endocrinology, Children's Hospital Colorado, University of Colorado Anschutz Medical Campus, Aurora, Colorado., Appiah LC; University of Colorado Department of Obstetrics and Gynecology, Section of Pediatric and Adolescent Gynecology, Aurora, Colorado., Alaniz VI; University of Colorado Department of Obstetrics and Gynecology, Section of Pediatric and Adolescent Gynecology, Aurora, Colorado., Chan CL; Department of Pediatrics, Section of Endocrinology, Children's Hospital Colorado, University of Colorado Anschutz Medical Campus, Aurora, Colorado.

Source: Journal of pediatric and adolescent gynecology [J Pediatr Adolesc Gynecol] 2025 Dec; Vol. 38 (6), pp. 724-730. Date of Electronic Publication: 2025 Aug 07.

Publication Type: Journal Article

Journal Info: Publisher: Elsevier Science Country of Publication: United States NLM ID: 9610774 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-4332 (Electronic) Linking ISSN: 10833188 NLM ISO Abbreviation: J Pediatr Adolesc Gynecol Subsets: MEDLINE

MeSH Terms: Prader-Willi Syndrome*/complications , Hypogonadism*/drug therapy , Hypogonadism*/etiology , Hormone Replacement Therapy* , Uterine Hemorrhage*/etiology, Humans ; Female ; Adolescent ; Retrospective Studies ; Young Adult ; Child ; Adult ; Child, Preschool ; Amenorrhea/etiology ; Amenorrhea/drug therapy ; Puberty, Delayed/etiology

Clinical Case of Comorbid Course of Metabolically Associated Fatty Liver and Pancreas Disease in a Child with Prader-Willi Syndrome.

Authors: Kryuchko TO; Department of Paediatrics No. 2, Poltava State Medical University. Address: St. 23 Shevchenko Street, Poltava, 36011, Ukraine., Nesina IM; Department of Paediatrics No. 2, Poltava State Medical University. Address: St. 23 Shevchenko Street, Poltava, 36011, Ukraine., Lytus SI; Department of Paediatrics No. 2, Poltava State Medical University. Address: St. 23 Shevchenko Street, Poltava, 36011, Ukraine., Poda OA; Department of Paediatrics No. 2, Poltava State Medical University. Address: St. 23 Shevchenko Street, Poltava, 36011, Ukraine., Bubyr LM; Department of Paediatrics No. 2, Poltava State Medical University. Address: St. 23 Shevchenko Street, Poltava, 36011, Ukraine.

Source: Journal of mother and child [J Mother Child] 2025 Nov 05; Vol. 29 (1), pp. 193-196. Date of Electronic Publication: 2025 Nov 05 (Print Publication: 2025).

Publication Type: Case Reports; Journal Article

Journal Info: Publisher: Sciendo Country of Publication: Poland NLM ID: 101771247 Publication Model: eCollection Cited Medium: Internet ISSN: 2719-535X (Electronic) Linking ISSN: 1428345X NLM ISO Abbreviation: J Mother Child Subsets: MEDLINE

MeSH Terms: Prader-Willi Syndrome*/complications , Exocrine Pancreatic Insufficiency*/etiology , Exocrine Pancreatic Insufficiency*/diagnosis , Fatty Liver*/complications, Humans ; Female ; Male ; Child ; Disease Progression

Growth hormone treatment in adults with Prader-Willi syndrome: an update.

Authors: Grugni G; Experimental Laboratory for Auxo-Endocrinological Research, Istituto Auxologico Italiano, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS), Piancavallo-Verbania, Italy., Sartorio A; Experimental Laboratory for Auxo-Endocrinological Research, Istituto Auxologico Italiano, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS), Piancavallo-Verbania, Italy.

Source: Expert review of endocrinology & metabolism [Expert Rev Endocrinol Metab] 2025 Nov; Vol. 20 (6), pp. 553-564. Date of Electronic Publication: 2025 Oct 28.

Publication Type: Journal Article; Review

Journal Info: Publisher: Taylor & Francis Country of Publication: England NLM ID: 101278293 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1744-8417 (Electronic) Linking ISSN: 17446651 NLM ISO Abbreviation: Expert Rev Endocrinol Metab Subsets: MEDLINE

MeSH Terms: Prader-Willi Syndrome*/drug therapy , Human Growth Hormone*/therapeutic use, Humans ; Adult ; Body Composition/drug effects ; Muscle Strength/drug effects

Glycemic and renal effects of SGLT2 Inhibitors in Prader-Willi syndrome: Benefits and risks.

Authors: Jacquot-Thierry J; Sorbonne Université, Inserm, Assistance Publique Hôpitaux de Paris, Service de Nutrition, CRMR PRADORT, Hôpital de la Pitié-Salpêtrière, Paris, France; Sorbonne Université, Inserm, Assistance Publique Hôpitaux de Paris, Service de Diabétologie, Hôpital de la Pitié-Salpêtrière, Paris, France., Chalopin S; Sorbonne Université, Inserm, Assistance Publique Hôpitaux de Paris, Service de Nutrition, CRMR PRADORT, Hôpital de la Pitié-Salpêtrière, Paris, France., Mosbah H; Department of Endocrinology, Diabetology and Nutrition, Poitiers University Hospital, INSERM, Centre d'Investigation Clinique CIC1402, Poitiers 86021, France; University of Poitiers, Poitiers 86000, France., Montastier É; Université de Toulouse, UMR1297, Department of Endocrinology and Nutrition, CRMR PRADORT, Rangueil Toulouse University Hospital, Toulouse, France., Mourre F; Assistance Publique Hôpitaux de Paris, SMR, CRMR PRADORT, Hôpital Marin, Hendaye, France., Gatta-Cherifi B; Department of Endocrinology, Diabetology, Nutrition. INSERMU1215, University of Bordeaux, Bordeaux University Hospital, Bordeaux, France., Bourry J; Lille University Hospital, Department of Diabetology and Nutrition, Lille, France., Guichard E; Sorbonne Université, Inserm, Assistance Publique Hôpitaux de Paris, Service de Nutrition, CRMR PRADORT, Hôpital de la Pitié-Salpêtrière, Paris, France., Faucher P; Sorbonne Université, Inserm, Assistance Publique Hôpitaux de Paris, Service de Nutrition, CRMR PRADORT, Hôpital de la Pitié-Salpêtrière, Paris, France., Poitou C; Sorbonne Université, Inserm, Assistance Publique Hôpitaux de Paris, Service de Nutrition, CRMR PRADORT, Hôpital de la Pitié-Salpêtrière, Paris, France; Sorbonne Université, Inserm Nutrition et Obésités: approches systémiques, NutriOmique, Paris, France. Electronic address: christine.poitou-bernert@aphp.fr., Amouyal C; Sorbonne Université, Inserm, Assistance Publique Hôpitaux de Paris, Service de Diabétologie, Hôpital de la Pitié-Salpêtrière, Paris, France; Sorbonne Université, Inserm Nutrition et Obésités: approches systémiques, NutriOmique, Paris, France. Electronic address: chloe.amouyal@aphp.fr.

Source: Diabetes & metabolism [Diabetes Metab] 2025 Nov; Vol. 51 (6), pp. 101704. Date of Electronic Publication: 2025 Sep 18.

Publication Type: Journal Article; Multicenter Study

Journal Info: Publisher: Masson Country of Publication: France NLM ID: 9607599 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1878-1780 (Electronic) Linking ISSN: 12623636 NLM ISO Abbreviation: Diabetes Metab Subsets: MEDLINE

MeSH Terms: Prader-Willi Syndrome*/drug therapy , Prader-Willi Syndrome*/complications , Prader-Willi Syndrome*/blood , Sodium-Glucose Transporter 2 Inhibitors*/therapeutic use , Sodium-Glucose Transporter 2 Inhibitors*/adverse effects , Diabetes Mellitus, Type 2*/drug therapy , Diabetes Mellitus, Type 2*/complications , Kidney*/drug effects, Humans ; Female ; Male ; Adult ; Retrospective Studies ; Middle Aged ; Blood Glucose/drug effects ; Blood Glucose/analysis ; Glycated Hemoglobin/analysis

Rescue of imprinted genes by epigenome editing in human cellular models of Prader-Willi syndrome.

Authors: Nemoto A; Department of Physiology, Keio University School of Medicine, Tokyo, Japan.; Keio University Regenerative Medicine Research Center, Kawasaki, Japan.; Department of Pediatrics and Adolescent Medicine, Tokyo Medical University, Tokyo, Japan., Imaizumi K; Department of Physiology, Keio University School of Medicine, Tokyo, Japan.; Keio University Regenerative Medicine Research Center, Kawasaki, Japan.; Department of Psychiatry and Behavioral Sciences, Stanford University, Stanford, CA, USA.; Stanford Brain Organogenesis, Wu Tsai Neurosciences Institute, Stanford University, Stanford, CA, USA., Miya F; Center for Medical Genetics, Keio University School of Medicine, Tokyo, Japan., Hiroi Y; Department of Pediatrics and Adolescent Medicine, Tokyo Medical University, Tokyo, Japan., Yamada M; Center for Medical Genetics, Keio University School of Medicine, Tokyo, Japan., Ideno H; Department of Physiology, Keio University School of Medicine, Tokyo, Japan., Saitoh S; Department of Pediatrics and Neonatology, Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan., Kosaki K; Center for Medical Genetics, Keio University School of Medicine, Tokyo, Japan., Okuno H; Department of Physiology, Keio University School of Medicine, Tokyo, Japan. okuno.hironobu.6v@tokyo-med.ac.jp.; Keio University Regenerative Medicine Research Center, Kawasaki, Japan. okuno.hironobu.6v@tokyo-med.ac.jp.; Department of Pediatrics and Adolescent Medicine, Tokyo Medical University, Tokyo, Japan. okuno.hironobu.6v@tokyo-med.ac.jp.; Center for Medical Genetics, Keio University School of Medicine, Tokyo, Japan. okuno.hironobu.6v@tokyo-med.ac.jp., Okano H; Department of Physiology, Keio University School of Medicine, Tokyo, Japan. hidokano@keio.jp.; Keio University Regenerative Medicine Research Center, Kawasaki, Japan. hidokano@keio.jp.

Source: Nature communications [Nat Commun] 2025 Oct 28; Vol. 16 (1), pp. 9442. Date of Electronic Publication: 2025 Oct 28.

Publication Type: Journal Article

Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

MeSH Terms: Prader-Willi Syndrome*/genetics , Prader-Willi Syndrome*/therapy , Genomic Imprinting*/genetics , Gene Editing*/methods , Epigenome*/genetics, Humans ; Induced Pluripotent Stem Cells/metabolism ; DNA Methylation/genetics ; CRISPR-Cas Systems ; Hypothalamus/metabolism ; Organoids/metabolism ; Chromosomes, Human, Pair 15/genetics ; Epigenesis, Genetic ; Epigenome Editing

Health outcomes of children with Prader-Willi or Angelman syndromes: a European population-based multicentre study.

Authors: Abate MV; Unit of Epidemiology of Rare Diseases and Congenital Anomalies, Institute of Clinical Physiology, National Research Council, Pisa, Italy mariavalentinaabate@cnr.it., Barisic I; Centre of Excellence for Reproductive and Regenerative Medicine, Children's Hospital Zagreb, Zagreb, Croatia.; Medical School, University of Zagreb, Zagreb, Croatia., Santoro M; Unit of Epidemiology of Rare Diseases and Congenital Anomalies, Institute of Clinical Physiology, National Research Council, Pisa, Italy., Coi A; Unit of Epidemiology of Rare Diseases and Congenital Anomalies, Institute of Clinical Physiology, National Research Council, Pisa, Italy., Tan J; NIHR GOSH BRC, London, UK., Garne E; Department of Paediatrics and Adolescent Medicine, Lillebaelt Hospital, Kolding, Denmark., Loane M; Institute of Nursing and Health Research, Ulster University, Belfast, UK., Odak L; Department of Medical and Laboratory Genetics, Endocrinology and Diabetology with Daily Care Unit, Children's Hospital Zagreb, Zagreb, Croatia., Ballardini E; Neonatal Intensive Care Unit, Paediatric Section, IMER Registry (Emilia Romagna Registry of Birth Defects), Department of Medical Sciences, University of Ferrara, Ferrara, Italy., Cavero-Carbonell C; Joint Research Unit on Rare Diseases, FISABIO-UVEG, FISABIO, Valencia, Spain., Gatt M; Department of Health Information, Directorate for Health Information and Research, Pietà, Malta., Gissler M; Finish Institute for Health and Welfare, Department of Data and Analytics, THL, Helsinki, Finland.; Academic Primary Health Care Centre, Region Stockholm, Stockholm, Sweden., Jordan S; Faculty of Medicine, Health and Life Science, Swansea University, Swansea, UK., Klungsøyr K; Department of Global Public Health and Primary Care, University of Bergen, Bergen, Norway.; Division of Mental and Physical Health, Norwegian Institute of Public Health, Bergen, Norway., Monier I; Centre of Research in Epidemiology and Statistics (CRESS), Université Paris Cité Faculté de Santé, Paris, France.; Obstetrical Perinatal and Pediatric Epidemiology Research Team (EPOPé), INSERM, Paris, France., Wellesley DG; Wessex Clinical Genetic Service, University Hospital Southampton NHS Foundation Trust Wessex Clinical Genetics Service, Southampton, UK., Morris JK; School of Health and Medical Sciences, St George's University, London, UK.

Source: Archives of disease in childhood [Arch Dis Child] 2025 Oct 17; Vol. 110 (11), pp. 899-904. Date of Electronic Publication: 2025 Oct 17.

Publication Type: Journal Article; Multicenter Study

Journal Info: Publisher: BMJ Pub. Group [etc.] Country of Publication: England NLM ID: 0372434 Publication Model: Electronic Cited Medium: Internet ISSN: 1468-2044 (Electronic) Linking ISSN: 00039888 NLM ISO Abbreviation: Arch Dis Child Subsets: MEDLINE

MeSH Terms: Prader-Willi Syndrome*/mortality , Prader-Willi Syndrome*/epidemiology , Prader-Willi Syndrome*/therapy , Angelman Syndrome*/mortality , Angelman Syndrome*/epidemiology , Angelman Syndrome*/therapy, Humans ; Male ; Female ; Child ; Child, Preschool ; Infant ; Europe/epidemiology ; Hospitalization/statistics & numerical data ; Length of Stay/statistics & numerical data ; Adolescent ; Registries ; Infant, Newborn

A proof-of-concept study of pitolisant for excessive daytime sleepiness in patients with Prader-Willi syndrome.

Authors: Revana A; Baylor College of Medicine, Texas Children's Hospital, Houston, Texas., Bhattacharjee R; Rady Children's Hospital, University of California San Diego, San Diego, California., Miller JL; University of Florida Health Shands Hospital, Gainesville, Florida., Chidekel A; Nemours Children's Health, Wilmington, Delaware., Khanna P; Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, Illinois., Ratnam S; Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, Illinois., Runyan G; Harmony Biosciences, Plymouth Meeting, Pennsylvania., Bauer E; Harmony Biosciences, Plymouth Meeting, Pennsylvania., Davis Rapchak K; Harmony Biosciences, Plymouth Meeting, Pennsylvania., Seiden D; Harmony Biosciences, Plymouth Meeting, Pennsylvania., Budur K; Harmony Biosciences, Plymouth Meeting, Pennsylvania., Dayno JM; Harmony Biosciences, Plymouth Meeting, Pennsylvania.

Source: Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine [J Clin Sleep Med] 2025 Nov 01; Vol. 21 (11), pp. 1893-1902.

Publication Type: Journal Article; Randomized Controlled Trial; Clinical Trial, Phase II

Journal Info: Publisher: American Academy of Sleep Medicine Country of Publication: United States NLM ID: 101231977 Publication Model: Print Cited Medium: Internet ISSN: 1550-9397 (Electronic) Linking ISSN: 15509389 NLM ISO Abbreviation: J Clin Sleep Med Subsets: MEDLINE

MeSH Terms: Disorders of Excessive Somnolence*/drug therapy , Disorders of Excessive Somnolence*/etiology , Piperidines*/therapeutic use , Piperidines*/administration & dosage , Prader-Willi Syndrome*/complications, Adolescent ; Adult ; Aged ; Child ; Female ; Humans ; Male ; Middle Aged ; Young Adult ; Dose-Response Relationship, Drug ; Double-Blind Method ; Proof of Concept Study ; Treatment Outcome

A Randomized Double-Blind Placebo-Controlled Trial of Guanfacine Extended Release for Aggression and Self-Injurious Behavior Associated With Prader-Willi Syndrome.

Authors: Singh D; Department of Psychiatry, Maimonides Medical Center, Brooklyn, New York, USA., Silver M; Research Administration, Maimonides Medical Center, Brooklyn, New York, USA., Jacob T; Department of Psychiatry, Maimonides Medical Center, Brooklyn, New York, USA.; Clinical and Translational Research Labs, Maimonides Medical Center, Brooklyn, New York, USA.

Source: American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics [Am J Med Genet B Neuropsychiatr Genet] 2025 Sep; Vol. 198 (6), pp. 62-70. Date of Electronic Publication: 2025 May 21.

Publication Type: Journal Article; Randomized Controlled Trial

Journal Info: Publisher: Wiley-Blackwell Country of Publication: United States NLM ID: 101235742 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1552-485X (Electronic) Linking ISSN: 15524841 NLM ISO Abbreviation: Am J Med Genet B Neuropsychiatr Genet Subsets: MEDLINE

MeSH Terms: Prader-Willi Syndrome*/drug therapy , Prader-Willi Syndrome*/complications , Prader-Willi Syndrome*/psychology , Self-Injurious Behavior*/drug therapy , Aggression*/drug effects , Guanfacine*/therapeutic use , Guanfacine*/administration & dosage , Guanfacine*/adverse effects, Humans ; Adolescent ; Female ; Male ; Double-Blind Method ; Child ; Adult ; Young Adult ; Delayed-Action Preparations ; Treatment Outcome

Role of mitochondrial function in the oxidative stress profile of children with Prader-Willi syndrome.

Authors: Carrasco-García Á; Department of Internal Medicine, Erasmus MC, University Medical Center Rotterdam, Rotterdam, the Netherlands; Department of Pediatrics, Obstetrics and Gynecology, University of Valencia, Valencia, Spain. Electronic address: a.carrascogarcia@erasmusmc.nl., Herrera G; Flow Cytometry Unit, Fundación Investigación Hospital Clínico Valencia, Instituto de Investigación Sanitaria INCLIVA-UCIM, University of Valencia, Spain., de Graaff LCG; Department of Internal Medicine, Erasmus MC, University Medical Center Rotterdam, Rotterdam, the Netherlands; Department of Internal Medicine, Radboudumc, Nijmegen, the Netherlands; Dutch National Reference Center for Prader-Willi Syndrome, Division of Endocrinology, Department of Internal Medicine, Erasmus University Medical Center Rotterdam, Rotterdam, the Netherlands; European Reference Network ERN-ITHACA; European Reference Network Endo-ERN., Visser JA; Department of Internal Medicine, Erasmus MC, University Medical Center Rotterdam, Rotterdam, the Netherlands., Dasí F; Universitat de València, Facultad de Medicina, Departamento de Fisiología, IIS INCLIVA, Valencia, Spain. Electronic address: francisco.dasi@uv.es., Codoñer-Franch P; Department of Pediatrics, Obstetrics and Gynecology, University of Valencia, Valencia, Spain.

Source: Free radical biology & medicine [Free Radic Biol Med] 2025 Sep; Vol. 237, pp. 397-402. Date of Electronic Publication: 2025 Jun 11.

Publication Type: Journal Article

Journal Info: Publisher: Elsevier Science Country of Publication: United States NLM ID: 8709159 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-4596 (Electronic) Linking ISSN: 08915849 NLM ISO Abbreviation: Free Radic Biol Med Subsets: MEDLINE

MeSH Terms: Prader-Willi Syndrome*/drug therapy , Prader-Willi Syndrome*/metabolism , Prader-Willi Syndrome*/pathology , Oxidative Stress*/drug effects , Mitochondria*/metabolism , Mitochondria*/drug effects , Mitochondria*/pathology , Human Growth Hormone*/therapeutic use , Obesity*/metabolism , Obesity*/drug therapy , Obesity*/pathology, Humans ; Adolescent ; Male ; Female ; Child ; Reactive Oxygen Species/metabolism ; Inflammation/pathology ; Inflammation/metabolism ; Inflammation/drug therapy ; Glutathione/metabolism

Long-term impact of growth hormone therapy on mortality and type 2 diabetes in Prader-Willi syndrome: a nationwide cohort study.

Authors: Choi YJ; Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul, Republic of Korea., Yang A; Department of Pediatrics, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea.

Source: Frontiers in endocrinology [Front Endocrinol (Lausanne)] 2025 Aug 22; Vol. 16, pp. 1642129. Date of Electronic Publication: 2025 Aug 22 (Print Publication: 2025).

Publication Type: Journal Article

Journal Info: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101555782 Publication Model: eCollection Cited Medium: Print ISSN: 1664-2392 (Print) Linking ISSN: 16642392 NLM ISO Abbreviation: Front Endocrinol (Lausanne) Subsets: MEDLINE

MeSH Terms: Prader-Willi Syndrome*/drug therapy , Prader-Willi Syndrome*/mortality , Prader-Willi Syndrome*/complications , Diabetes Mellitus, Type 2*/epidemiology , Diabetes Mellitus, Type 2*/mortality , Diabetes Mellitus, Type 2*/etiology , Human Growth Hormone*/therapeutic use , Human Growth Hormone*/adverse effects, Humans ; Female ; Male ; Adult ; Cohort Studies ; Middle Aged ; Republic of Korea/epidemiology ; Young Adult ; Adolescent ; Incidence ; Child ; Risk Factors ; Follow-Up Studies

Improvement in body composition of Japanese participants with Prader-Willi syndrome following somatropin treatment: an open-label, multi cohort Phase 3 study.

Authors: Kawai M; Department of Gastroenterology, Nutrition and Endocrinology, Osaka Women's and Children's Hospital, Izumi 594-1101, Japan., Murakami N; Department of Pediatrics, Dokkyo Medical University Saitama Medical Center, Koshigaya 343-8555, Japan., Horikawa R; Division of Endocrinology and Metabolism, National Center for Child Health and Development, Setagaya 157-8535, Japan., Muroya K; Department of Endocrinology and Metabolism, Kanagawa Children's Medical Center, Yokohama 232-8555, Japan., Fujisawa Y; Department of Pediatrics, Hamamatsu University School of Medicine, Hamamatsu 431-3192, Japan., Hoshino Y; Pfizer R&D Japan, Shibuya 151-8589, Japan., Okayama A; Pfizer R&D Japan, Shibuya 151-8589, Japan., Sato T; Pfizer Japan Inc., Shibuya 151-8589, Japan., Ebata N; Pfizer Japan Inc., Shibuya 151-8589, Japan., Ogata T; Departments of Pediatrics and Biochemistry, Hamamatsu University School of Medicine, Hamamatsu 431-3192, Japan.

Source: Endocrine journal [Endocr J] 2025 Aug 01; Vol. 72 (8), pp. 925-935. Date of Electronic Publication: 2025 May 28.

Publication Type: Journal Article; Clinical Trial, Phase III; Multicenter Study

Journal Info: Publisher: Japan Endocrine Society Country of Publication: Japan NLM ID: 9313485 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1348-4540 (Electronic) Linking ISSN: 09188959 NLM ISO Abbreviation: Endocr J Subsets: MEDLINE

MeSH Terms: Prader-Willi Syndrome*/drug therapy , Prader-Willi Syndrome*/physiopathology , Body Composition*/drug effects , Human Growth Hormone*/therapeutic use , Human Growth Hormone*/adverse effects, Humans ; Female ; Male ; Child ; Adult ; Adolescent ; Japan ; Young Adult ; Treatment Outcome ; Child, Preschool ; Cohort Studies ; Recombinant Proteins/therapeutic use ; Middle Aged ; East Asian People