Applying phylogenomics to understand the emergence of Shiga-toxin-producing Escherichia coli O157:H7 strains causing severe human disease in the UK

Συγγραφείς: Dallman, TJ, Ashton, PM, Byrne, L, Perry, NT, Petrovska, L, Ellis, R, Allison, L, Hanson, M, Holmes, A, Gunn, GJ, Chase-Topping, ME, Woolhouse, MEJ, Grant, KA, Gally, DL, Wain, J, Jenkins, C

Πηγή: Dallman, TJ, Ashton, PM, Byrne, L, Perry, NT, Petrovska, L, Ellis, R, Allison, L, Hanson, M, Holmes, A, Gunn, GJ, Chase-Topping, ME, Woolhouse, MEJ, Grant, KA, Gally, DL, Wain, J & Jenkins, C 2015, 'Applying phylogenomics to understand the emergence of Shiga-toxin-producing Escherichia coli O157:H7 strains causing severe human disease in the UK', Microbial Genomics, vol. 1, no. 3, pp. 1-13. https://doi.org/10.1099/mgen.0.000029

Θεματικοί όροι: Emerging infections, Eschericia coli, Genomics, One Health, Public health microbiology, Shiga toxin, /dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_being, name=SDG 3 - Good Health and Well-being

Περιγραφή αρχείου: application/pdf

Relation: info:eu-repo/semantics/altIdentifier/eissn/2057-5858

Διαθεσιμότητα: https://pure.sruc.ac.uk/en/publications/23442962-c124-460f-b0a9-1b1292042df9
https://doi.org/10.1099/mgen.0.000029
https://pure.sruc.ac.uk/ws/files/14866426/14155.pdf

Structural mechanism governing the directionality of bridge recombination.

Συγγραφείς: Hiraizumi M; Department of Chemistry and Biotechnology, Graduate School of Engineering, The University of Tokyo, Tokyo, Japan., Athukoralage JS; Arc Institute, Palo Alto, CA, USA., Perry NT; Arc Institute, Palo Alto, CA, USA.; Department of Bioengineering, University of California, Berkeley, Berkeley, CA, USA.; San Francisco Graduate Program in Bioengineering, University of California, Berkeley, Berkeley, CA, USA., Tsujimoto E; Department of Chemistry and Biotechnology, Graduate School of Engineering, The University of Tokyo, Tokyo, Japan., Shiojiri N; Department of Chemistry and Biotechnology, Graduate School of Engineering, The University of Tokyo, Tokyo, Japan., Nagahata N; Department of Chemistry and Biotechnology, Graduate School of Engineering, The University of Tokyo, Tokyo, Japan., Lee L; Arc Institute, Palo Alto, CA, USA., Sun G; Arc Institute, Palo Alto, CA, USA., Durrant MG; Arc Institute, Palo Alto, CA, USA.; Department of Bioengineering, University of California, Berkeley, Berkeley, CA, USA., Chandrasekaran SS; Arc Institute, Palo Alto, CA, USA., Konermann S; Arc Institute, Palo Alto, CA, USA.; Department of Biochemistry, School of Medicine, Stanford University, Stanford, CA, USA., Yamashita K; Structural Biology Division, Research Center for Advanced Science and Technology, The University of Tokyo, Tokyo, Japan., Hsu PD; Arc Institute, Palo Alto, CA, USA. patrick@arcinstitute.org.; Department of Bioengineering, University of California, Berkeley, Berkeley, CA, USA. patrick@arcinstitute.org.; Innovative Genomics Institute, University of California, Berkeley, Berkeley, CA, USA. patrick@arcinstitute.org.; Center for Computational Biology, University of California, Berkeley, Berkeley, CA, USA. patrick@arcinstitute.org., Nishimasu H; Department of Chemistry and Biotechnology, Graduate School of Engineering, The University of Tokyo, Tokyo, Japan. nisimasu@g.ecc.u-tokyo.ac.jp.; Structural Biology Division, Research Center for Advanced Science and Technology, The University of Tokyo, Tokyo, Japan. nisimasu@g.ecc.u-tokyo.ac.jp.; Inamori Research Institute for Science, Kyoto, Japan. nisimasu@g.ecc.u-tokyo.ac.jp.

Πηγή: Nature [Nature] 2026 Oct; Vol. 658 (8134), pp. 269-278. Date of Electronic Publication: 2026 Aug 12.

Τύπος έκδοσης: Journal Article

Στοιχεία περιοδικού: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 0410462 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-4687 (Electronic) Linking ISSN: 00280836 NLM ISO Abbreviation: Nature Subsets: MEDLINE

Ιατρικοί όροι (MeSH): Escherichia coli*/genetics , Escherichia coli*/enzymology , DNA Transposable Elements*/genetics , Recombinases*/metabolism , Recombinases*/chemistry , Recombinases*/ultrastructure , Recombination, Genetic* , Cryoelectron Microscopy*, DNA, Circular/genetics ; DNA, Circular/chemistry ; DNA, Circular/metabolism ; DNA, Circular/ultrastructure ; DNA/chemistry ; DNA/metabolism ; DNA/ultrastructure ; DNA/genetics ; Models, Molecular ; Substrate Specificity

Megabase-scale human genome rearrangement with programmable bridge recombinases.

Συγγραφείς: Perry NT; Arc Institute, Palo Alto, CA, USA.; Department of Bioengineering, University of California, Berkeley, Berkeley, CA, USA.; University of California, Berkeley - University of California, San Francisco, Graduate Program in Bioengineering, Berkeley, CA, USA., Bartie LJ; Arc Institute, Palo Alto, CA, USA.; Department of Bioengineering, University of California, Berkeley, Berkeley, CA, USA.; University of California, Berkeley - University of California, San Francisco, Graduate Program in Bioengineering, Berkeley, CA, USA., Katrekar D; Arc Institute, Palo Alto, CA, USA., Gonzalez GA; Arc Institute, Palo Alto, CA, USA., Durrant MG; Arc Institute, Palo Alto, CA, USA., Pai JJ; Arc Institute, Palo Alto, CA, USA., Fanton A; Arc Institute, Palo Alto, CA, USA.; Department of Bioengineering, University of California, Berkeley, Berkeley, CA, USA.; University of California, Berkeley - University of California, San Francisco, Graduate Program in Bioengineering, Berkeley, CA, USA., Martins JQ; Arc Institute, Palo Alto, CA, USA.; Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA, USA., Hiraizumi M; Department of Chemistry and Biotechnology, Graduate School of Engineering, The University of Tokyo, Bunkyo-ku, Tokyo, Japan., Ricci-Tam C; Arc Institute, Palo Alto, CA, USA., Nishimasu H; Department of Chemistry and Biotechnology, Graduate School of Engineering, The University of Tokyo, Bunkyo-ku, Tokyo, Japan.; Structural Biology Division, Research Center for Advanced Science and Technology, The University of Tokyo, Meguro-ku, Tokyo, Japan.; Inamori Research Institute for Science, Shimogyo-ku, Kyoto, Japan., Konermann S; Arc Institute, Palo Alto, CA, USA.; Department of Biochemistry, Stanford University School of Medicine, Stanford, CA, USA., Hsu PD; Arc Institute, Palo Alto, CA, USA.; Department of Bioengineering, University of California, Berkeley, Berkeley, CA, USA.; Center for Computational Biology, University of California, Berkeley, Berkeley, CA, USA.

Πηγή: Science (New York, N.Y.) [Science] 2026 Mar 12; Vol. 391 (6790), pp. eadz0276. Date of Electronic Publication: 2026 Mar 12.

Τύπος έκδοσης: Journal Article

Στοιχεία περιοδικού: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 0404511 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1095-9203 (Electronic) Linking ISSN: 00368075 NLM ISO Abbreviation: Science Subsets: MEDLINE

Ιατρικοί όροι (MeSH): Recombinases*/genetics , Recombinases*/metabolism , DNA Nucleotidyltransferases*/genetics , DNA Nucleotidyltransferases*/metabolism , DNA Nucleotidyltransferases*/chemistry , Genome, Human* , Gene Rearrangement*, Escherichia coli/genetics ; DNA/genetics ; Humans ; Plasmids ; Genetic Engineering

Structural mechanism of bridge RNA-guided recombination.

Συγγραφείς: Hiraizumi M; Department of Chemistry and Biotechnology, Graduate School of Engineering, The University of Tokyo, Tokyo, Japan., Perry NT; Arc Institute, Palo Alto, CA, USA.; Department of Bioengineering, University of California, Berkeley, Berkeley, CA, USA.; San Francisco Graduate Program in Bioengineering, University of California, Berkeley, Berkeley, CA, USA., Durrant MG; Arc Institute, Palo Alto, CA, USA., Soma T; Department of Chemistry and Biotechnology, Graduate School of Engineering, The University of Tokyo, Tokyo, Japan., Nagahata N; Department of Chemistry and Biotechnology, Graduate School of Engineering, The University of Tokyo, Tokyo, Japan., Okazaki S; Structural Biology Division, Research Center for Advanced Science and Technology, The University of Tokyo, Tokyo, Japan., Athukoralage JS; Arc Institute, Palo Alto, CA, USA., Isayama Y; Structural Biology Division, Research Center for Advanced Science and Technology, The University of Tokyo, Tokyo, Japan., Pai JJ; Arc Institute, Palo Alto, CA, USA., Pawluk A; Arc Institute, Palo Alto, CA, USA., Konermann S; Arc Institute, Palo Alto, CA, USA.; Department of Biochemistry, Stanford University School of Medicine, Stanford, CA, USA., Yamashita K; Structural Biology Division, Research Center for Advanced Science and Technology, The University of Tokyo, Tokyo, Japan., Hsu PD; Arc Institute, Palo Alto, CA, USA. patrick@arcinstitute.org.; Department of Bioengineering, University of California, Berkeley, Berkeley, CA, USA. patrick@arcinstitute.org.; Center for Computational Biology, University of California, Berkeley, Berkeley, CA, USA. patrick@arcinstitute.org., Nishimasu H; Department of Chemistry and Biotechnology, Graduate School of Engineering, The University of Tokyo, Tokyo, Japan. nisimasu@g.ecc.u-tokyo.ac.jp.; Structural Biology Division, Research Center for Advanced Science and Technology, The University of Tokyo, Tokyo, Japan. nisimasu@g.ecc.u-tokyo.ac.jp.; Inamori Research Institute for Science, Kyoto, Japan. nisimasu@g.ecc.u-tokyo.ac.jp.

Πηγή: Nature [Nature] 2024 Jun; Vol. 630 (8018), pp. 994-1002. Date of Electronic Publication: 2024 Jun 26.

Τύπος έκδοσης: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural

Στοιχεία περιοδικού: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 0410462 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-4687 (Electronic) Linking ISSN: 00280836 NLM ISO Abbreviation: Nature Subsets: MEDLINE

Ιατρικοί όροι (MeSH): DNA*/chemistry , DNA*/metabolism , DNA*/ultrastructure , RNA, Untranslated*/chemistry , RNA, Untranslated*/genetics , RNA, Untranslated*/metabolism , RNA, Untranslated*/ultrastructure , Recombination, Genetic*, DNA Transposable Elements/genetics ; Recombinases/chemistry ; Recombinases/genetics ; Recombinases/metabolism ; Catalytic Domain ; Cryoelectron Microscopy ; Models, Molecular ; Nucleic Acid Conformation ; Protein Multimerization ; Substrate Specificity

Bridge RNAs direct programmable recombination of target and donor DNA.

Συγγραφείς: Durrant MG; Arc Institute, Palo Alto, CA, USA.; Department of Bioengineering, University of California, Berkeley, Berkeley, CA, USA., Perry NT; Arc Institute, Palo Alto, CA, USA.; Department of Bioengineering, University of California, Berkeley, Berkeley, CA, USA.; University of California, Berkeley-University of California, San Francisco Graduate Program in Bioengineering, Berkeley, CA, USA., Pai JJ; Arc Institute, Palo Alto, CA, USA., Jangid AR; Arc Institute, Palo Alto, CA, USA.; Department of Bioengineering, University of California, Berkeley, Berkeley, CA, USA., Athukoralage JS; Arc Institute, Palo Alto, CA, USA., Hiraizumi M; Department of Chemistry and Biotechnology, Graduate School of Engineering, University of Tokyo, Tokyo, Japan., McSpedon JP; Arc Institute, Palo Alto, CA, USA., Pawluk A; Arc Institute, Palo Alto, CA, USA., Nishimasu H; Department of Chemistry and Biotechnology, Graduate School of Engineering, University of Tokyo, Tokyo, Japan.; Structural Biology Division, Research Center for Advanced Science and Technology, University of Tokyo, Tokyo, Japan.; Department of Biological Sciences, Graduate School of Science, University of Tokyo, Tokyo, Japan.; Inamori Research Institute for Science, Kyoto, Japan.; Japan Science and Technology Agency, Core Research for Evolutional Science and Technology, Saitama, Japan., Konermann S; Arc Institute, Palo Alto, CA, USA.; Department of Biochemistry, Stanford University School of Medicine, Stanford, CA, USA., Hsu PD; Arc Institute, Palo Alto, CA, USA. patrick@arcinstitute.org.; Department of Bioengineering, University of California, Berkeley, Berkeley, CA, USA. patrick@arcinstitute.org.; Center for Computational Biology, University of California, Berkeley, Berkeley, CA, USA. patrick@arcinstitute.org.

Πηγή: Nature [Nature] 2024 Jun; Vol. 630 (8018), pp. 984-993. Date of Electronic Publication: 2024 Jun 26.

Τύπος έκδοσης: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural

Στοιχεία περιοδικού: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 0410462 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-4687 (Electronic) Linking ISSN: 00280836 NLM ISO Abbreviation: Nature Subsets: MEDLINE

Ιατρικοί όροι (MeSH): DNA*/genetics , DNA*/metabolism , Recombination, Genetic*/genetics , RNA, Untranslated*/genetics , RNA, Untranslated*/metabolism, DNA Transposable Elements/genetics ; Mutagenesis, Insertional/genetics ; Recombinases/metabolism ; Recombinases/genetics ; Base Pairing ; Base Sequence

Bridge RNAs direct modular and programmable recombination of target and donor DNA.

Συγγραφείς: Durrant MG; Arc Institute, 3181 Porter Drive, Palo Alto, CA 94304, USA.; Department of Bioengineering, University of California, Berkeley, Berkeley, CA, USA., Perry NT; Arc Institute, 3181 Porter Drive, Palo Alto, CA 94304, USA.; Department of Bioengineering, University of California, Berkeley, Berkeley, CA, USA.; University of California, Berkeley - University of California, San Francisco Graduate Program in Bioengineering, Berkeley, CA, USA., Pai JJ; Arc Institute, 3181 Porter Drive, Palo Alto, CA 94304, USA., Jangid AR; Arc Institute, 3181 Porter Drive, Palo Alto, CA 94304, USA.; Department of Bioengineering, University of California, Berkeley, Berkeley, CA, USA., Athukoralage JS; Arc Institute, 3181 Porter Drive, Palo Alto, CA 94304, USA., Hiraizumi M; Department of Chemistry and Biotechnology, Graduate School of Engineering, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8656, Japan., McSpedon JP; Arc Institute, 3181 Porter Drive, Palo Alto, CA 94304, USA., Pawluk A; Arc Institute, 3181 Porter Drive, Palo Alto, CA 94304, USA., Nishimasu H; Department of Chemistry and Biotechnology, Graduate School of Engineering, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8656, Japan.; Structural Biology Division, Research Center for Advanced Science and Technology, The University of Tokyo, 4-6-1 Komaba, Meguro-ku, Tokyo 153-8904, Japan.; Department of Biological Sciences, Graduate School of Science, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033, Japan.; Inamori Research Institute for Science, 620 Suiginya-cho, Shimogyo-ku, Kyoto 600-8411, Japan.; Japan Science and Technology Agency, Core Research for Evolutional Science and Technology, 4-1-8, Honcho, Kawaguchi-shi, Saitama 332-0012, Japan., Konermann S; Arc Institute, 3181 Porter Drive, Palo Alto, CA 94304, USA.; Department of Biochemistry, Stanford University School of Medicine, Stanford, CA, USA., Hsu PD; Arc Institute, 3181 Porter Drive, Palo Alto, CA 94304, USA.; Department of Bioengineering, University of California, Berkeley, Berkeley, CA, USA.; Center for Computational Biology, University of California, Berkeley, Berkeley, CA, USA.

Πηγή: BioRxiv : the preprint server for biology [bioRxiv] 2024 Jan 26. Date of Electronic Publication: 2024 Jan 26.

Τύπος έκδοσης: Preprint; Journal Article

Στοιχεία περιοδικού: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE

Systematic discovery of recombinases for efficient integration of large DNA sequences into the human genome.

Συγγραφείς: Durrant MG; Arc Institute, Palo Alto, CA, USA.; Department of Bioengineering, University of California, Berkeley, Berkeley, CA, USA.; Department of Genetics, Stanford University, Stanford, CA, USA., Fanton A; Department of Bioengineering, University of California, Berkeley, Berkeley, CA, USA.; University of California, Berkeley-University of California, San Francisco Graduate Program in Bioengineering, Berkeley, CA, USA., Tycko J; Department of Genetics, Stanford University, Stanford, CA, USA., Hinks M; Department of Bioengineering, Stanford University, Stanford, CA, USA., Chandrasekaran SS; Department of Bioengineering, University of California, Berkeley, Berkeley, CA, USA.; University of California, Berkeley-University of California, San Francisco Graduate Program in Bioengineering, Berkeley, CA, USA., Perry NT; Department of Bioengineering, University of California, Berkeley, Berkeley, CA, USA.; University of California, Berkeley-University of California, San Francisco Graduate Program in Bioengineering, Berkeley, CA, USA., Schaepe J; Department of Bioengineering, Stanford University, Stanford, CA, USA., Du PP; Department of Genetics, Stanford University, Stanford, CA, USA.; Cancer Biology Program, Stanford University, Stanford, CA, USA., Lotfy P; Laboratory of Molecular and Cell Biology, Salk Institute for Biological Studies, La Jolla, CA, USA., Bassik MC; Department of Genetics, Stanford University, Stanford, CA, USA. bassik@stanford.edu., Bintu L; Department of Bioengineering, Stanford University, Stanford, CA, USA. lbintu@stanford.edu., Bhatt AS; Department of Genetics, Stanford University, Stanford, CA, USA. asbhatt@stanford.edu.; Department of Medicine (Hematology), Stanford University, Stanford, CA, USA. asbhatt@stanford.edu., Hsu PD; Arc Institute, Palo Alto, CA, USA. pdhsu@berkeley.edu.; Department of Bioengineering, University of California, Berkeley, Berkeley, CA, USA. pdhsu@berkeley.edu.; Laboratory of Molecular and Cell Biology, Salk Institute for Biological Studies, La Jolla, CA, USA. pdhsu@berkeley.edu.; Innovative Genomics Institute, University of California, Berkeley, Berkeley, CA, USA. pdhsu@berkeley.edu.; Center for Computational Biology, University of California, Berkeley, Berkeley, CA, USA. pdhsu@berkeley.edu.

Πηγή: Nature biotechnology [Nat Biotechnol] 2023 Apr; Vol. 41 (4), pp. 488-499. Date of Electronic Publication: 2022 Oct 10.

Τύπος έκδοσης: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.

Στοιχεία περιοδικού: Publisher: Nature America Publishing Country of Publication: United States NLM ID: 9604648 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1546-1696 (Electronic) Linking ISSN: 10870156 NLM ISO Abbreviation: Nat Biotechnol Subsets: MEDLINE

Ιατρικοί όροι (MeSH): Integrases* , Genetic Engineering*, Humans ; Genome, Human ; Transfection ; Genomic Library

Author Correction: Augmenting and directing long-range CRISPR-mediated activation in human cells.

Συγγραφείς: Tak YE; Molecular Pathology Unit, Massachusetts General Hospital, Charlestown, MA, USA.; Center for Cancer Research, Massachusetts General Hospital, Charlestown, MA, USA.; Center for Computational and Integrative Biology, Massachusetts General Hospital, Charlestown, MA, USA.; Department of Pathology, Harvard Medical School, Boston, MA, USA., Horng JE; Molecular Pathology Unit, Massachusetts General Hospital, Charlestown, MA, USA.; Center for Cancer Research, Massachusetts General Hospital, Charlestown, MA, USA.; Center for Computational and Integrative Biology, Massachusetts General Hospital, Charlestown, MA, USA., Perry NT; Molecular Pathology Unit, Massachusetts General Hospital, Charlestown, MA, USA.; Center for Cancer Research, Massachusetts General Hospital, Charlestown, MA, USA.; Center for Computational and Integrative Biology, Massachusetts General Hospital, Charlestown, MA, USA., Schultz HT; Molecular Pathology Unit, Massachusetts General Hospital, Charlestown, MA, USA.; Center for Cancer Research, Massachusetts General Hospital, Charlestown, MA, USA.; Center for Computational and Integrative Biology, Massachusetts General Hospital, Charlestown, MA, USA., Iyer S; Molecular Pathology Unit, Massachusetts General Hospital, Charlestown, MA, USA., Yao Q; Molecular Pathology Unit, Massachusetts General Hospital, Charlestown, MA, USA.; Center for Cancer Research, Massachusetts General Hospital, Charlestown, MA, USA.; Department of Pathology, Harvard Medical School, Boston, MA, USA.; Cell Circuits and Epigenomics Program, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Zou LS; Cell Circuits and Epigenomics Program, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Department of Biostatistics, Harvard T. H. Chan School of Public Health, Boston, MA, USA., Aryee MJ; Molecular Pathology Unit, Massachusetts General Hospital, Charlestown, MA, USA.; Center for Cancer Research, Massachusetts General Hospital, Charlestown, MA, USA.; Department of Pathology, Harvard Medical School, Boston, MA, USA.; Cell Circuits and Epigenomics Program, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Department of Biostatistics, Harvard T. H. Chan School of Public Health, Boston, MA, USA., Pinello L; Molecular Pathology Unit, Massachusetts General Hospital, Charlestown, MA, USA.; Center for Cancer Research, Massachusetts General Hospital, Charlestown, MA, USA.; Department of Pathology, Harvard Medical School, Boston, MA, USA.; Cell Circuits and Epigenomics Program, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Joung JK; Molecular Pathology Unit, Massachusetts General Hospital, Charlestown, MA, USA. jjoung@mgh.harvard.edu.; Center for Cancer Research, Massachusetts General Hospital, Charlestown, MA, USA. jjoung@mgh.harvard.edu.; Center for Computational and Integrative Biology, Massachusetts General Hospital, Charlestown, MA, USA. jjoung@mgh.harvard.edu.; Department of Pathology, Harvard Medical School, Boston, MA, USA. jjoung@mgh.harvard.edu.

Πηγή: Nature methods [Nat Methods] 2022 Jul; Vol. 19 (7), pp. 899.

Τύπος έκδοσης: Published Erratum

Στοιχεία περιοδικού: Publisher: Nature Pub. Group Country of Publication: United States NLM ID: 101215604 Publication Model: Print Cited Medium: Internet ISSN: 1548-7105 (Electronic) Linking ISSN: 15487091 NLM ISO Abbreviation: Nat Methods Subsets: MEDLINE; PubMed not MEDLINE

Genome-wide functional perturbation of human microsatellite repeats using engineered zinc finger transcription factors.

Συγγραφείς: Tak YE; Molecular Pathology Unit and Center for Cancer Research, Massachusetts General Hospital, Charlestown, MA, USA.; Center for Computational and Integrative Biology, Massachusetts General Hospital, Charlestown, MA, USA.; Department of Pathology, Harvard Medical School, Boston, MA, USA., Boulay G; Molecular Pathology Unit and Center for Cancer Research, Massachusetts General Hospital, Charlestown, MA, USA.; Department of Pathology, Harvard Medical School, Boston, MA, USA.; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Lee L; Molecular Pathology Unit and Center for Cancer Research, Massachusetts General Hospital, Charlestown, MA, USA., Iyer S; Molecular Pathology Unit and Center for Cancer Research, Massachusetts General Hospital, Charlestown, MA, USA., Perry NT; Molecular Pathology Unit and Center for Cancer Research, Massachusetts General Hospital, Charlestown, MA, USA.; Center for Computational and Integrative Biology, Massachusetts General Hospital, Charlestown, MA, USA., Schultz HT; Molecular Pathology Unit and Center for Cancer Research, Massachusetts General Hospital, Charlestown, MA, USA.; Center for Computational and Integrative Biology, Massachusetts General Hospital, Charlestown, MA, USA., Garcia SP; Molecular Pathology Unit and Center for Cancer Research, Massachusetts General Hospital, Charlestown, MA, USA., Broye L; Institute of Pathology, Department of Experimental Pathology, Centre Hospitalier Universitaire Vaudois, University of Lausanne, 1011 Lausanne, Switzerland., Horng JE; Molecular Pathology Unit and Center for Cancer Research, Massachusetts General Hospital, Charlestown, MA, USA.; Center for Computational and Integrative Biology, Massachusetts General Hospital, Charlestown, MA, USA., Rengarajan S; Molecular Pathology Unit and Center for Cancer Research, Massachusetts General Hospital, Charlestown, MA, USA., Naigles B; Molecular Pathology Unit and Center for Cancer Research, Massachusetts General Hospital, Charlestown, MA, USA., Volorio A; Molecular Pathology Unit and Center for Cancer Research, Massachusetts General Hospital, Charlestown, MA, USA.; Institute of Pathology, Department of Experimental Pathology, Centre Hospitalier Universitaire Vaudois, University of Lausanne, 1011 Lausanne, Switzerland., Sander JD; Molecular Pathology Unit and Center for Cancer Research, Massachusetts General Hospital, Charlestown, MA, USA.; Center for Computational and Integrative Biology, Massachusetts General Hospital, Charlestown, MA, USA.; Department of Pathology, Harvard Medical School, Boston, MA, USA., Gong J; Molecular Pathology Unit and Center for Cancer Research, Massachusetts General Hospital, Charlestown, MA, USA.; Center for Computational and Integrative Biology, Massachusetts General Hospital, Charlestown, MA, USA., Riggi N; Institute of Pathology, Department of Experimental Pathology, Centre Hospitalier Universitaire Vaudois, University of Lausanne, 1011 Lausanne, Switzerland., Joung JK; Molecular Pathology Unit and Center for Cancer Research, Massachusetts General Hospital, Charlestown, MA, USA.; Center for Computational and Integrative Biology, Massachusetts General Hospital, Charlestown, MA, USA.; Department of Pathology, Harvard Medical School, Boston, MA, USA., Rivera MN; Molecular Pathology Unit and Center for Cancer Research, Massachusetts General Hospital, Charlestown, MA, USA.; Department of Pathology, Harvard Medical School, Boston, MA, USA.; Broad Institute of MIT and Harvard, Cambridge, MA, USA.

Πηγή: Cell genomics [Cell Genom] 2022 Apr 13; Vol. 2 (4).

Τύπος έκδοσης: Journal Article

Στοιχεία περιοδικού: Publisher: Elsevier, Inc Country of Publication: United States NLM ID: 9918284260106676 Publication Model: Print Cited Medium: Internet ISSN: 2666-979X (Electronic) Linking ISSN: 2666979X NLM ISO Abbreviation: Cell Genom Subsets: PubMed not MEDLINE

Augmenting and directing long-range CRISPR-mediated activation in human cells.

Συγγραφείς: Tak YE; Molecular Pathology Unit, Massachusetts General Hospital, Charlestown, MA, USA.; Center for Cancer Research, Massachusetts General Hospital, Charlestown, MA, USA.; Center for Computational and Integrative Biology, Massachusetts General Hospital, Charlestown, MA, USA.; Department of Pathology, Harvard Medical School, Boston, MA, USA., Horng JE; Molecular Pathology Unit, Massachusetts General Hospital, Charlestown, MA, USA.; Center for Cancer Research, Massachusetts General Hospital, Charlestown, MA, USA.; Center for Computational and Integrative Biology, Massachusetts General Hospital, Charlestown, MA, USA., Perry NT; Molecular Pathology Unit, Massachusetts General Hospital, Charlestown, MA, USA.; Center for Cancer Research, Massachusetts General Hospital, Charlestown, MA, USA.; Center for Computational and Integrative Biology, Massachusetts General Hospital, Charlestown, MA, USA., Schultz HT; Molecular Pathology Unit, Massachusetts General Hospital, Charlestown, MA, USA.; Center for Cancer Research, Massachusetts General Hospital, Charlestown, MA, USA.; Center for Computational and Integrative Biology, Massachusetts General Hospital, Charlestown, MA, USA., Iyer S; Molecular Pathology Unit, Massachusetts General Hospital, Charlestown, MA, USA., Yao Q; Molecular Pathology Unit, Massachusetts General Hospital, Charlestown, MA, USA.; Center for Cancer Research, Massachusetts General Hospital, Charlestown, MA, USA.; Department of Pathology, Harvard Medical School, Boston, MA, USA.; Cell Circuits and Epigenomics Program, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Zou LS; Cell Circuits and Epigenomics Program, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Department of Biostatistics, Harvard T. H. Chan School of Public Health, Boston, MA, USA., Aryee MJ; Molecular Pathology Unit, Massachusetts General Hospital, Charlestown, MA, USA.; Center for Cancer Research, Massachusetts General Hospital, Charlestown, MA, USA.; Department of Pathology, Harvard Medical School, Boston, MA, USA.; Cell Circuits and Epigenomics Program, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Department of Biostatistics, Harvard T. H. Chan School of Public Health, Boston, MA, USA., Pinello L; Molecular Pathology Unit, Massachusetts General Hospital, Charlestown, MA, USA.; Center for Cancer Research, Massachusetts General Hospital, Charlestown, MA, USA.; Department of Pathology, Harvard Medical School, Boston, MA, USA.; Cell Circuits and Epigenomics Program, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Joung JK; Molecular Pathology Unit, Massachusetts General Hospital, Charlestown, MA, USA. jjoung@mgh.harvard.edu.; Center for Cancer Research, Massachusetts General Hospital, Charlestown, MA, USA. jjoung@mgh.harvard.edu.; Center for Computational and Integrative Biology, Massachusetts General Hospital, Charlestown, MA, USA. jjoung@mgh.harvard.edu.; Department of Pathology, Harvard Medical School, Boston, MA, USA. jjoung@mgh.harvard.edu.

Πηγή: Nature methods [Nat Methods] 2021 Sep; Vol. 18 (9), pp. 1075-1081. Date of Electronic Publication: 2021 Aug 05.

Τύπος έκδοσης: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

Στοιχεία περιοδικού: Publisher: Nature Pub. Group Country of Publication: United States NLM ID: 101215604 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1548-7105 (Electronic) Linking ISSN: 15487091 NLM ISO Abbreviation: Nat Methods Subsets: MEDLINE

Ιατρικοί όροι (MeSH): Clustered Regularly Interspaced Short Palindromic Repeats* , Promoter Regions, Genetic*, Gene Targeting/*methods , Transcription Factors/*genetics, Apolipoprotein C-III/genetics ; Apolipoproteins A/genetics ; Interleukin-2 Receptor alpha Subunit/genetics ; MyoD Protein/genetics ; beta-Globins/genetics ; Alleles ; Cell Line ; Enhancer Elements, Genetic ; Humans ; Polymorphism, Single Nucleotide ; Transcriptional Activation

Design and Structure-Activity Relationships of Isothiocyanates as Potent and Selective N-Acylethanolamine-Hydrolyzing Acid Amidase Inhibitors.

Συγγραφείς: Malamas MS; Northeastern University, Boston, Massachusetts 02115, United States., Pavlopoulos S; Center for Drug Discovery, Northeastern University, Boston, Massachusetts 02115, United States., Alapafuja SO; MAK Scientific LLC, 151 South Bedford Street, Burlington, Massachusetts 01803, United States., Farah SI; Center for Drug Discovery, Northeastern University, Boston, Massachusetts 02115, United States., Zvonok A; Center for Drug Discovery, Northeastern University, Boston, Massachusetts 02115, United States., Mohammad KA; Center for Drug Discovery, Northeastern University, Boston, Massachusetts 02115, United States., West J; Center for Drug Discovery, Northeastern University, Boston, Massachusetts 02115, United States., Perry NT; Center for Drug Discovery, Northeastern University, Boston, Massachusetts 02115, United States., Pelekoudas DN; Center for Drug Discovery, Northeastern University, Boston, Massachusetts 02115, United States., Rajarshi G; Center for Drug Discovery, Northeastern University, Boston, Massachusetts 02115, United States., Shields C; Center for Drug Discovery, Northeastern University, Boston, Massachusetts 02115, United States., Chandrashekhar H; Center for Drug Discovery, Northeastern University, Boston, Massachusetts 02115, United States., Wood J; Center for Drug Discovery, Northeastern University, Boston, Massachusetts 02115, United States., Makriyannis A; Center for Drug Discovery and Departments of Chemistry and Chemical Biology and Pharmaceutical Sciences, Northeastern University, Boston, Massachusetts 02115, United States.

Πηγή: Journal of medicinal chemistry [J Med Chem] 2021 May 13; Vol. 64 (9), pp. 5956-5972. Date of Electronic Publication: 2021 Apr 26.

Τύπος έκδοσης: Journal Article; Research Support, N.I.H., Extramural

Στοιχεία περιοδικού: Publisher: American Chemical Society Country of Publication: United States NLM ID: 9716531 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-4804 (Electronic) Linking ISSN: 00222623 NLM ISO Abbreviation: J Med Chem Subsets: MEDLINE

Ιατρικοί όροι (MeSH): Drug Design*, Amidohydrolases/*antagonists & inhibitors , Enzyme Inhibitors/*chemistry , Enzyme Inhibitors/*pharmacology , Isothiocyanates/*chemistry , Isothiocyanates/*pharmacology, Amidohydrolases/metabolism ; Drug Stability ; Humans ; Hydrolysis ; Structure-Activity Relationship

Evaluation of chromogenic selective agar (CHROMagar STEC) for the direct detection of Shiga toxin-producing Escherichia coli from faecal specimens.

Συγγραφείς: Jenkins C; National Infection Service, Public Health England, London, NW9 5HT, UK., Perry NT; National Infection Service, Public Health England, London, NW9 5HT, UK., Godbole G; National Infection Service, Public Health England, London, NW9 5HT, UK., Gharbia S; National Infection Service, Public Health England, London, NW9 5HT, UK.

Πηγή: Journal of medical microbiology [J Med Microbiol] 2020 Mar; Vol. 69 (3), pp. 487-491.

Τύπος έκδοσης: Evaluation Study; Journal Article

Στοιχεία περιοδικού: Publisher: Microbiology Society Country of Publication: England NLM ID: 0224131 Publication Model: Print Cited Medium: Internet ISSN: 1473-5644 (Electronic) Linking ISSN: 00222615 NLM ISO Abbreviation: J Med Microbiol Subsets: MEDLINE

Ιατρικοί όροι (MeSH): Escherichia coli Infections/*diagnosis , Shiga-Toxigenic Escherichia coli/*isolation & purification, Escherichia coli Infections/microbiology ; Feces/microbiology ; Shiga Toxin/genetics ; Shiga-Toxigenic Escherichia coli/genetics ; Agar ; Chromogenic Compounds ; Humans

Design and synthesis of cyanamides as potent and selective N-acylethanolamine acid amidase inhibitors.

Συγγραφείς: Malamas MS; Center for Drug Discovery and Departments of Chemistry and Chemical Biology and Pharmaceutical Sciences, Northeastern University, Boston, MA 02115, United States. Electronic address: m.malamas@northeastern.edu., Farah SI; Center for Drug Discovery and Departments of Chemistry and Chemical Biology and Pharmaceutical Sciences, Northeastern University, Boston, MA 02115, United States., Lamani M; Center for Drug Discovery and Departments of Chemistry and Chemical Biology and Pharmaceutical Sciences, Northeastern University, Boston, MA 02115, United States., Pelekoudas DN; Center for Drug Discovery and Departments of Chemistry and Chemical Biology and Pharmaceutical Sciences, Northeastern University, Boston, MA 02115, United States., Perry NT; Center for Drug Discovery and Departments of Chemistry and Chemical Biology and Pharmaceutical Sciences, Northeastern University, Boston, MA 02115, United States., Rajarshi G; Center for Drug Discovery and Departments of Chemistry and Chemical Biology and Pharmaceutical Sciences, Northeastern University, Boston, MA 02115, United States., Miyabe CY; Center for Drug Discovery and Departments of Chemistry and Chemical Biology and Pharmaceutical Sciences, Northeastern University, Boston, MA 02115, United States., Chandrashekhar H; Center for Drug Discovery and Departments of Chemistry and Chemical Biology and Pharmaceutical Sciences, Northeastern University, Boston, MA 02115, United States., West J; Center for Drug Discovery and Departments of Chemistry and Chemical Biology and Pharmaceutical Sciences, Northeastern University, Boston, MA 02115, United States., Pavlopoulos S; Center for Drug Discovery and Departments of Chemistry and Chemical Biology and Pharmaceutical Sciences, Northeastern University, Boston, MA 02115, United States., Makriyannis A; Center for Drug Discovery and Departments of Chemistry and Chemical Biology and Pharmaceutical Sciences, Northeastern University, Boston, MA 02115, United States.

Πηγή: Bioorganic & medicinal chemistry [Bioorg Med Chem] 2020 Jan 01; Vol. 28 (1), pp. 115195. Date of Electronic Publication: 2019 Nov 11.

Τύπος έκδοσης: Journal Article; Research Support, N.I.H., Extramural

Στοιχεία περιοδικού: Publisher: Elsevier Science Country of Publication: England NLM ID: 9413298 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1464-3391 (Electronic) Linking ISSN: 09680896 NLM ISO Abbreviation: Bioorg Med Chem Subsets: MEDLINE

Ιατρικοί όροι (MeSH): Drug Design*, Amidohydrolases/*antagonists & inhibitors , Cyanamide/*pharmacology , Enzyme Inhibitors/*pharmacology, Amidohydrolases/metabolism ; Cyanamide/chemical synthesis ; Cyanamide/chemistry ; Enzyme Inhibitors/chemical synthesis ; Enzyme Inhibitors/chemistry ; Animals ; Dose-Response Relationship, Drug ; Mice ; Models, Molecular ; Molecular Structure ; Rats ; Structure-Activity Relationship

Short-term evolution of Shiga toxin-producing Escherichia coli O157:H7 between two food-borne outbreaks.

Συγγραφείς: Cowley LA; 1​Gastrointestinal Bacterial Reference Unit, 61 Colindale Avenue, Public Health England, NW9 5EQ London, UK., Dallman TJ; 1​Gastrointestinal Bacterial Reference Unit, 61 Colindale Avenue, Public Health England, NW9 5EQ London, UK., Fitzgerald S; 2​Division of Infection and Immunity, The Roslin Institute and Royal (Dick) School of Veterinary Studies, University of Edinburgh, EH25 9RG Roslin, UK., Irvine N; 3​Public Health Agency, 12-22 Linenhall St, BT2 8BS Belfast, Northern Ireland., Rooney PJ; 4​Microbiology Laboratory, Royal Victoria Hospital, BT12 6BA Belfast, Northern Ireland., McAteer SP; 2​Division of Infection and Immunity, The Roslin Institute and Royal (Dick) School of Veterinary Studies, University of Edinburgh, EH25 9RG Roslin, UK., Day M; 1​Gastrointestinal Bacterial Reference Unit, 61 Colindale Avenue, Public Health England, NW9 5EQ London, UK., Perry NT; 1​Gastrointestinal Bacterial Reference Unit, 61 Colindale Avenue, Public Health England, NW9 5EQ London, UK., Bono JL; 5​U.S. Meat Animal Research Center, Agricultural Research Service, U.S. Department of Agriculture, Clay Center, Nebraska 68933-0166, USA., Jenkins C; 1​Gastrointestinal Bacterial Reference Unit, 61 Colindale Avenue, Public Health England, NW9 5EQ London, UK., Gally DL; 2​Division of Infection and Immunity, The Roslin Institute and Royal (Dick) School of Veterinary Studies, University of Edinburgh, EH25 9RG Roslin, UK.

Πηγή: Microbial genomics [Microb Genom] 2016 Sep 08; Vol. 2 (9), pp. e000084. Date of Electronic Publication: 2016 Sep 08 (Print Publication: 2016).

Τύπος έκδοσης: Journal Article

Στοιχεία περιοδικού: Publisher: Microbiology Society Country of Publication: England NLM ID: 101671820 Publication Model: eCollection Cited Medium: Print ISSN: 2057-5858 (Print) Linking ISSN: 20575858 NLM ISO Abbreviation: Microb Genom Subsets: MEDLINE

Ιατρικοί όροι (MeSH): Escherichia coli Infections/*microbiology , Escherichia coli O157/*genetics , Genome, Bacterial/*genetics, Escherichia coli Infections/epidemiology ; Escherichia coli Infections/transmission ; Plasmids/genetics ; Prophages/genetics ; Africa, Northern ; Disease Outbreaks ; Evolution, Molecular ; Humans ; Middle East

Whole Genome Sequencing for Public Health Surveillance of Shiga Toxin-Producing Escherichia coli Other than Serogroup O157.

Συγγραφείς: Chattaway MA; Gastrointestinal Bacteria Reference Unit, Public Health England London, UK., Dallman TJ; Gastrointestinal Bacteria Reference Unit, Public Health England London, UK., Gentle A; Gastrointestinal Bacteria Reference Unit, Public Health England London, UK., Wright MJ; Gastrointestinal Bacteria Reference Unit, Public Health England London, UK., Long SE; Gastrointestinal Bacteria Reference Unit, Public Health England London, UK., Ashton PM; Gastrointestinal Bacteria Reference Unit, Public Health England London, UK., Perry NT; Gastrointestinal Bacteria Reference Unit, Public Health England London, UK., Jenkins C; Gastrointestinal Bacteria Reference Unit, Public Health England London, UK.

Πηγή: Frontiers in microbiology [Front Microbiol] 2016 Mar 03; Vol. 7, pp. 258. Date of Electronic Publication: 2016 Mar 03 (Print Publication: 2016).

Τύπος έκδοσης: Journal Article

Στοιχεία περιοδικού: Publisher: Frontiers Research Foundation Country of Publication: Switzerland NLM ID: 101548977 Publication Model: eCollection Cited Medium: Print ISSN: 1664-302X (Print) Linking ISSN: 1664302X NLM ISO Abbreviation: Front Microbiol Subsets: PubMed not MEDLINE

Whole-genome sequencing for national surveillance of Shiga toxin-producing Escherichia coli O157.

Συγγραφείς: Dallman TJ; Public Health England, London., Byrne L; Public Health England, London., Ashton PM; Public Health England, London., Cowley LA; Public Health England, London., Perry NT; Public Health England, London., Adak G; Public Health England, London., Petrovska L; Animal and Plant Health Agency, Addlestone, Surrey, United Kingdom., Ellis RJ; Animal and Plant Health Agency, Addlestone, Surrey, United Kingdom., Elson R; Public Health England, London., Underwood A; Public Health England, London., Green J; Public Health England, London., Hanage WP; Harvard School of Public Health, Boston, Massachusetts., Jenkins C; Public Health England, London., Grant K; Public Health England, London., Wain J; University of East Anglia, Norwich, United Kingdom.

Πηγή: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America [Clin Infect Dis] 2015 Aug 01; Vol. 61 (3), pp. 305-12. Date of Electronic Publication: 2015 Apr 17.

Τύπος έκδοσης: Journal Article; Research Support, N.I.H., Extramural

Στοιχεία περιοδικού: Publisher: Oxford University Press Country of Publication: United States NLM ID: 9203213 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1537-6591 (Electronic) Linking ISSN: 10584838 NLM ISO Abbreviation: Clin Infect Dis Subsets: MEDLINE

Ιατρικοί όροι (MeSH): Public Health Surveillance*, Escherichia coli Infections/*microbiology , Genome, Bacterial/*genetics , Shiga-Toxigenic Escherichia coli/*genetics, DNA, Bacterial/analysis ; DNA, Bacterial/genetics ; Shiga-Toxigenic Escherichia coli/classification ; Disease Outbreaks ; Humans ; Phylogeny ; Retrospective Studies ; Sequence Analysis, DNA

Epidemiology and microbiology of Shiga toxin-producing Escherichia coli other than serogroup O157 in England, 2009-2013.

Συγγραφείς: Byrne L; Gastrointestinal, Emerging and Zoonotic Infections Department, Public Health England, 61 Colindale Avenue, London NW9 5EQ, UK., Vanstone GL; Department of Medical Microbiology, Royal Free London NHS Foundation Trust, London NW3 2QG, UK., Perry NT; Gastrointestinal Bacteria Reference Unit, Public Health England, 61 Colindale Avenue, London NW9 5HT, UK., Launders N; Gastrointestinal, Emerging and Zoonotic Infections Department, Public Health England, 61 Colindale Avenue, London NW9 5EQ, UK., Adak GK; Gastrointestinal, Emerging and Zoonotic Infections Department, Public Health England, 61 Colindale Avenue, London NW9 5EQ, UK., Godbole G; Gastrointestinal Bacteria Reference Unit, Public Health England, 61 Colindale Avenue, London NW9 5HT, UK., Grant KA; Gastrointestinal Bacteria Reference Unit, Public Health England, 61 Colindale Avenue, London NW9 5HT, UK., Smith R; Department of Medical Microbiology, Royal Free London NHS Foundation Trust, London NW3 2QG, UK., Jenkins C; Gastrointestinal Bacteria Reference Unit, Public Health England, 61 Colindale Avenue, London NW9 5HT, UK.

Πηγή: Journal of medical microbiology [J Med Microbiol] 2014 Sep; Vol. 63 (Pt 9), pp. 1181-1188. Date of Electronic Publication: 2014 Jun 13.

Τύπος έκδοσης: Journal Article; Research Support, Non-U.S. Gov't

Στοιχεία περιοδικού: Publisher: Microbiology Society Country of Publication: England NLM ID: 0224131 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1473-5644 (Electronic) Linking ISSN: 00222615 NLM ISO Abbreviation: J Med Microbiol Subsets: MEDLINE

Ιατρικοί όροι (MeSH): Escherichia coli Infections/*epidemiology , Shiga-Toxigenic Escherichia coli/*classification , Shiga-Toxigenic Escherichia coli/*isolation & purification, Adhesins, Bacterial/genetics ; England/epidemiology ; Escherichia coli Proteins/genetics ; Feces/microbiology ; Shiga Toxin 1/genetics ; Shiga Toxin 2/genetics ; Trans-Activators/genetics ; Adolescent ; Adult ; Aged ; Aged, 80 and over ; Case-Control Studies ; Child ; Child, Preschool ; Female ; Genotype ; Humans ; Incidence ; Infant ; Male ; Middle Aged ; Polymerase Chain Reaction ; Serotyping ; Young Adult

The serological response to Verocytotoxigenic Escherichia coli in patients with haemolytic uraemic syndrome.

Συγγραφείς: Chart H; Laboratory of Enteric Pathogens, Specialist and Reference Microbiology Division, Health Protection Agency, London, UK. henrik.chart@hpa.org.uk, Perry NT

Πηγή: Letters in applied microbiology [Lett Appl Microbiol] 2004; Vol. 38 (5), pp. 351-4.

Τύπος έκδοσης: Journal Article

Στοιχεία περιοδικού: Publisher: Oxford University Press Country of Publication: England NLM ID: 8510094 Publication Model: Print Cited Medium: Print ISSN: 0266-8254 (Print) Linking ISSN: 02668254 NLM ISO Abbreviation: Lett Appl Microbiol Subsets: MEDLINE

Ιατρικοί όροι (MeSH): Antibodies, Bacterial/*blood , Escherichia coli/*immunology , Hemolytic-Uremic Syndrome/*microbiology , Shiga Toxins/*metabolism, Escherichia coli/metabolism ; Escherichia coli Infections/immunology ; Escherichia coli Infections/microbiology ; Escherichia coli O157/immunology ; Hemolytic-Uremic Syndrome/immunology ; Lipopolysaccharides/immunology ; Adolescent ; Child ; Enzyme-Linked Immunosorbent Assay ; Female ; Humans ; Immunoblotting ; Male ; Serotyping

The expression of an R3 lipopolysaccharide-core by pathotypes of Escherichia coli.

Συγγραφείς: Chart H; Laboratory of Enteric Pathogens, Division of Gastrointestinal Infections, Central Public Health Laboratory, London, UK. henrik.chart@hpa.org.uk, Perry NT, Jenkins C

Πηγή: Journal of applied microbiology [J Appl Microbiol] 2004; Vol. 96 (5), pp. 982-6.

Τύπος έκδοσης: Journal Article; Research Support, Non-U.S. Gov't

Στοιχεία περιοδικού: Publisher: Oxford University Press Country of Publication: England NLM ID: 9706280 Publication Model: Print Cited Medium: Print ISSN: 1364-5072 (Print) Linking ISSN: 13645072 NLM ISO Abbreviation: J Appl Microbiol Subsets: MEDLINE

Ιατρικοί όροι (MeSH): Escherichia coli/*genetics , Lipopolysaccharides/*analysis, Escherichia coli O157/genetics ; Genes, Bacterial/genetics ; Nucleic Acid Amplification Techniques/methods ; Shiga Toxins/biosynthesis ; Animals ; Cattle ; Humans ; Polymerase Chain Reaction ; Serotyping

Analysis of saliva for antibodies to the LPS of Escherichia coli O157 in patients with serum antibodies to E. coli O157 LPS.

Συγγραφείς: Chart H; Laboratory of Enteric Pathogens, Division of Gastrointestinal Infections, Central Public Health Laboratory, 61 Colindale Avenue, London NW9 5HT, UK., Perry NT; Laboratory of Enteric Pathogens, Division of Gastrointestinal Infections, Central Public Health Laboratory, 61 Colindale Avenue, London NW9 5HT, UK., Willshaw GA; Laboratory of Enteric Pathogens, Division of Gastrointestinal Infections, Central Public Health Laboratory, 61 Colindale Avenue, London NW9 5HT, UK., Cheasty T; Laboratory of Enteric Pathogens, Division of Gastrointestinal Infections, Central Public Health Laboratory, 61 Colindale Avenue, London NW9 5HT, UK.

Πηγή: Journal of medical microbiology [J Med Microbiol] 2003 Jul; Vol. 52 (Pt 7), pp. 569-572.

Τύπος έκδοσης: Journal Article

Στοιχεία περιοδικού: Publisher: Microbiology Society Country of Publication: England NLM ID: 0224131 Publication Model: Print Cited Medium: Print ISSN: 0022-2615 (Print) Linking ISSN: 00222615 NLM ISO Abbreviation: J Med Microbiol Subsets: MEDLINE

Ιατρικοί όροι (MeSH): Antibodies, Bacterial/*analysis , Antibodies, Bacterial/*blood , Escherichia coli Infections/*immunology , Escherichia coli O157/*immunology , Lipopolysaccharides/*immunology , Saliva/*immunology, Escherichia coli Infections/blood ; Adolescent ; Adult ; Child ; Child, Preschool ; Female ; Humans ; Male ; Middle Aged