A multiscale modeling approach to study the role of mechanics and inflammation in the pathophysiology of articular cartilage.

Συγγραφείς: Mukherjee, Satanik, Lesage, Raphaelle, Geris, Liesbet

Πηγή: Computers in Biology and Medicine, 211, 111737 (2026-07-15)

Θεματικοί όροι: Articular cartilage, Finite element analysis, Gene regulatory network, Mechanotransduction, Multiscale modeling, Osteoarthritis, Animals, Humans, Finite Element Analysis, Computer Simulation, Stress, Mechanical, Cartilage, Articular/physiopathology, Cartilage, Articular/metabolism, Cartilage, Articular/pathology, Models, Biological, Osteoarthritis/physiopathology, Osteoarthritis/metabolism, Osteoarthritis/pathology, Chondrocytes/metabolism, Chondrocytes/pathology, Inflammation/physiopathology, Inflammation/metabolism, Inflammation/pathology, Mechanotransduction, Cellular, Articular cartilages, Chondrocytes, Finite element analyse, Finite element modelling (FEM), Gene regulatory networks, Length scale, Mechanical loading, Cartilage, Articular, Inflammation, Health Informatics, Computer Science Applications, Engineering, computing & technology, Ingénierie, informatique & technologie

Relation: https://api.elsevier.com/content/article/PII:S001048252600301X?httpAccept=text/xml; urn:issn:0010-4825; urn:issn:1879-0534

Σύνδεσμος πρόσβασης: https://orbi.uliege.be/handle/2268/346988

The effect of cyclic fluid perfusion on the proinflammatory tissue environment in osteoarthritis using equine joint-on-a-chip models

Συγγραφείς: Heidenberger, Johannes, Reihs, Eva I., Strauss, Jonathan, Frauenlob, Martin, Gültekin, Sinan, Gerner, Iris, Tögel, Stefan, Ertl, Peter, Windhager, Reinhard, Jenner, Florien, Rothbauer, Mario

Πηγή: Lab on a Chip. 25:2256-2269

Θεματικοί όροι: Inflammation, Chondrocytes Metabolism, Chondrocytes Cytology, Osteoarthritis Metabolism, Inflammation Pathology, Synoviocytes, Joints Pathology, Coculture Techniques, Chondrocytes Pathology, Perfusion, Synoviocytes Pathology, Chondrocytes, Lab-On-A-Chip Devices, Osteoarthritis Pathology, Synoviocytes Cytology, Osteoarthritis, Animals, Joints, Horses, Synoviocytes Metabolism, Cells, Cultured

Περιγραφή αρχείου: application/pdf

Σύνδεσμος πρόσβασης: https://pubmed.ncbi.nlm.nih.gov/40162708

Systemic and joint adipose tissue lipids and their role in osteoarthritis

Συγγραφείς: Zapata-Linares, N., Loisay, L., de Haro, D., Berenbaum, F., Hügle, T., Geurts, J., Houard, X.

Πηγή: Biochimie, vol. 227, no. Pt B, pp. 130-138

Θεματικοί όροι: Humans, Adipose Tissue/metabolism, Osteoarthritis/metabolism, Osteoarthritis/pathology, Lipid Metabolism, Animals, Adipokines/metabolism, Joints/metabolism, Joints/pathology, Lipids, Obesity/metabolism, Bone marrow adipose tissue, Infrapatellar fat pad, Intra-articular adipose tissue, Osteoarthritis, Adipose Tissue, Adipokines, Joints, Obesity

Περιγραφή αρχείου: application/pdf

Σύνδεσμος πρόσβασης: https://pubmed.ncbi.nlm.nih.gov/39343353
http://nbn-resolving.org/urn/resolver.pl?urn=urn:nbn:ch:serval-BIB_755B687633962
https://serval.unil.ch/resource/serval:BIB_755B68763396.P001/REF.pdf
https://serval.unil.ch/notice/serval:BIB_755B68763396

RNA sequencing uncovers key players of cartilage calcification: potential implications for osteoarthritis pathogenesis

Συγγραφείς: Bernabei, Ilaria, Faure, Elodie, Wegrzyn, Julien, Bertheaume, Nicolas, Falgayrac, Guillaume, Hugle, Thomas, Nasi, Sonia, Busso, Nathalie

Συνεισφορές: Falgayrac, Guillaume

Πηγή: Rheumatology (Oxford)
Rheumatology, vol. 64, no. 5, pp. 3151-3159

Θεματικοί όροι: Cartilage, Articular, Calciprotein, Sequence Analysis, RNA, Calcinosis, RNA sequencing, [SDV] Life Sciences [q-bio], osteoarthritis, Chondrocytes/metabolism, Chondrocytes/pathology, Osteoarthritis/genetics, Osteoarthritis/metabolism, Osteoarthritis/pathology, Animals, Humans, Mice, Calcinosis/genetics, Calcinosis/metabolism, Cartilage, Articular/pathology, Cartilage, Articular/metabolism, Cells, Cultured, OA, calciprotein particles, cartilage calcification genes, Chondrocytes, Basic Science, Osteoarthritis, osteoarthritis cartilage calcification genes calciprotein particles RNA sequencing, Cartilage Diseases

Περιγραφή αρχείου: application/pdf

Σύνδεσμος πρόσβασης: https://pubmed.ncbi.nlm.nih.gov/39432678
http://nbn-resolving.org/urn/resolver.pl?urn=urn:nbn:ch:serval-BIB_566F17970BB84
https://serval.unil.ch/notice/serval:BIB_566F17970BB8
https://serval.unil.ch/resource/serval:BIB_566F17970BB8.P001/REF.pdf

Subchondral bone marrow adipose tissue lipolysis regulates bone formation in hand osteoarthritis

Συγγραφείς: Mauro Maniglio, Léa Loisay, Diego de Haro, Alexander Antoniadis, Thomas Hügle, Jeroen Geurts

Πηγή: Osteoarthritis and cartilage, vol. 33, no. 3, pp. 322-329

Θεματικοί όροι: Male, Humans, Lipolysis/physiology, Osteoarthritis/metabolism, Osteoarthritis/pathology, Osteoarthritis/physiopathology, Middle Aged, Female, Adipose Tissue/metabolism, Adipose Tissue/pathology, Aged, Osteogenesis/physiology, Bone Marrow/metabolism, Bone Marrow/pathology, Osteoblasts/metabolism, Osteoblasts/pathology, Adipocytes/metabolism, Adipocytes/pathology, Hand Joints/metabolism, Hand Joints/pathology, Lipase/metabolism, Bone, Bone marrow adipose tissue, Hand OA, Lipolysis, Osteoblast, Osteoblasts, Hand Joints, Lipase, Adipose Tissue, Osteogenesis, Bone Marrow, Osteoarthritis, Adipocytes, 610 Medicine & health

Περιγραφή αρχείου: application/pdf

Σύνδεσμος πρόσβασης: https://pubmed.ncbi.nlm.nih.gov/39725154
https://pure.amsterdamumc.nl/en/publications/4626eb20-73e2-4434-b7cf-a6321fb130c7
https://doi.org/10.1016/j.joca.2024.12.005
https://serval.unil.ch/resource/serval:BIB_9AC304E3EC2E.P001/REF.pdf
http://nbn-resolving.org/urn/resolver.pl?urn=urn:nbn:ch:serval-BIB_9AC304E3EC2E9
https://serval.unil.ch/notice/serval:BIB_9AC304E3EC2E

Exploration of bioactive variants of the BMP7-derived p[63-82] peptide for ameliorating the OA-associated chondrocyte phenotype

Συγγραφείς: Steijns,Jessica S J, Welting,Tim J M, Cremers,Andy, Akker,Guus G H van den, Emans,Pieter J, Rhijn, Lodewijk W van, Caron,Marjolein M J, MS Orthopaedie Algemeen

Θεματικοί όροι: Male, Peptide Fragments/pharmacology, Middle Aged, Synovial Fluid/metabolism, Bone Morphogenetic Protein 7/pharmacology, Osteoarthritis/metabolism, Phenotype, Chondrocytes/drug effects, Osteoarthritis, Knee/metabolism, Journal Article, Humans, Female, Cells, Cultured, Aged

Περιγραφή αρχείου: text/plain

Σύνδεσμος πρόσβασης: https://dspace.library.uu.nl/handle/1874/467088

Three decades of advancements in osteoarthritis research: insights from transcriptomic, proteomic, and metabolomic studies

Συγγραφείς: Muhammad Farooq Rai, Kelsey H. Collins, Annemarie Lang, Tristan Maerz, Jeroen Geurts, Cristina Ruiz-Romero, Ronald K. June, Yolande Ramos, Sarah J. Rice, Shabana Amanda Ali, Chiara Pastrello, Igor Jurisica, C. Thomas Appleton, Jason S. Rockel, Mohit Kapoor

Πηγή: Osteoarthritis Cartilage
Osteoarthritis and cartilage, vol. 32, no. 4, pp. 385-397

Θεματικοί όροι: Humans, Proteomics, Metabolomics, Gene Expression Profiling, Proteome, Osteoarthritis/genetics, Osteoarthritis/metabolism, Multi-omics, Spatial-omics, Transcriptomics, Osteoarthritis, Article, 3. Good health

Περιγραφή αρχείου: application/pdf

Σύνδεσμος πρόσβασης: https://pubmed.ncbi.nlm.nih.gov/38049029
https://serval.unil.ch/resource/serval:BIB_D1B4F6D830DD.P001/REF.pdf
https://serval.unil.ch/notice/serval:BIB_D1B4F6D830DD
http://nbn-resolving.org/urn/resolver.pl?urn=urn:nbn:ch:serval-BIB_D1B4F6D830DD6

Osteoarthritis year in review 2023: Biology

Συγγραφείς: Anke J. Roelofs, Cosimo De Bari

Συνεισφορές: University of Aberdeen.Medical Sciences, University of Aberdeen.Aberdeen Centre for Arthritis and Musculoskeletal Health (ACAMH), University of Aberdeen.Applied Medicine

Πηγή: Roelofs, A J & De Bari, C 2024, 'Osteoarthritis year in review 2023 : Biology', Osteoarthritis and Cartilage, vol. 32, no. 2, pp. 148-158. https://doi.org/10.1016/j.joca.2023.11.002

Θεματικοί όροι: Inflammation, Cartilage, Articular, subchondral bone, Inflammation/metabolism, synovium, R Medicine (General), Bone and Bones/metabolism, R1, Bone and Bones, 3. Good health, Arthritis Research UK (ARUK), Osteoarthritis/metabolism, osteoarthritis, ageing, Cartilage, Articular/metabolism, Osteoarthritis, Humans, pain, cartilage, Biology, Ageing, Cartilage, Pain, Subchondral bone, Synovium

Περιγραφή αρχείου: application/pdf

Σύνδεσμος πρόσβασης: https://pubmed.ncbi.nlm.nih.gov/37944663
https://www.research.ed.ac.uk/en/publications/896168ca-78cc-42ba-be38-28743a6cad28
https://doi.org/10.1016/j.joca.2023.11.002
https://hdl.handle.net/20.500.11820/896168ca-78cc-42ba-be38-28743a6cad28
https://www.pure.ed.ac.uk/ws/files/501962512/Osteoarthritis_year_in_review_2023_Biology.pdf

Dexamethasone: a double-edged sword in the treatment of osteoarthritis

Συγγραφείς: Tarasova, Karyna, Arteaga, Maria Belen, Kidtiwong, Angkana, Gueltekin, Sinan, Bileck, Andrea, Gerner, Christopher, Gerner, Iris, Jenner, Florien

Πηγή: Sci Rep
Scientific Reports, Vol 15, Iss 1, Pp 1-13 (2025)

Θεματικοί όροι: Triamcinolone Acetonide Pharmacology, Chondrocytes Metabolism, Science, Anti-Inflammatory Agents, Apoptosis, Chondrocytes Drug Effects, Triamcinolone, Senescence, Triamcinolone Acetonide, Article, Dexamethasone, Cellular Senescence Drug Effects, Chondrocytes, Osteoarthritis Pathology, Osteoarthritis, Humans, Inflammation Drug Therapy, Glucocorticoids, Cells, Cultured, Cellular Senescence, Osteoarthritis Drug Therapy, Cell Proliferation, Inflammation, Glucocorticoids Pharmacology, Gene Expression Profiling, Anti-Inflammatory Agents Pharmacology, Osteoarthritis Metabolism, Cell Proliferation Drug Effects, Gene Expression Regulation Drug Effects, Chondrocytes Pathology, Dexamethasone Therapeutic Use, Dexamethasone Pharmacology, Gene Expression Regulation, Medicine, Apoptosis Drug Effects

Περιγραφή αρχείου: application/pdf

Σύνδεσμος πρόσβασης: https://pubmed.ncbi.nlm.nih.gov/40195473
https://doaj.org/article/194006edd23b4f7aaa0a959c0531241b
https://phaidra.vetmeduni.ac.at/o:4102
https://doi.org/10.1038/s41598-025-96050-2

Interdisciplinary management of FGF23-related phosphate wasting syndromes: a Consensus Statement on the evaluation, diagnosis and care of patients with X-linked hypophosphataemia

Συγγραφείς: Trombetti, Andrea, Al-Daghri, Nasser, Brandi, Maria Luisa, Cannata-Andía, Jorge B, CAVALIER, Etienne, Chandran, Manju, Chaussain, Catherine, Cipullo, Lucia, Cooper, Cyrus, Haffner, Dieter, Harvengt, Pol, Harvey, Nicholas C, Javaid, Muhammad Kassim, Jiwa, Famida, Kanis, John A, Laslop, Andrea, Laurent, Michaël R, Linglart, Agnès, Marques, Andréa, Mindler, Gabriel T, Minisola, Salvatore, Yerro, María Concepción Prieto, Rosa, Mario Miguel, Seefried, Lothar, Vlaskovska, Mila, Zanchetta, María Belén, Rizzoli, René

Συνεισφορές: Ribeiro, Kira, ACU Research Bank, King Saud University Riyadh (KSU), Università degli Studi di Firenze = University of Florence = Université de Florence (UniFI), Université de Liège = University of Liège = Universiteit van Luik = Universität Lüttich (ULiège), Centre Hospitalier Universitaire de Liège (CHU-Liège), National University Hospital Singapore (NUH), Pathologies, imagerie et biothérapies oro-faciales = Orofacial pathologies, imaging and biotherapies (URP 2496), Université Paris Cité (UPCité), University Hospital Southampton NHS Foundation Trust, University of Southampton, University of Sheffield Sheffield, Scientific Office, Austrian Agency for Health and Food Safety (AGES), Société de Culture Légumière (SCL), Physiologie et physiopathologie endocriniennes (PHYSENDO), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris-Saclay, Université Paris-Saclay, Hôpital Bicêtre AP-HP, Le Kremlin-Bicêtre, Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Centro Hospitalar e Universitário Coimbra

Πηγή: Nature Reviews Endocrinology. 18:366-384

Θεματικοί όροι: 0301 basic medicine, Fibroblast Growth Factor-23/metabolism, Hypophosphatemia, Endocrinology, Diabetes and Metabolism, Familial Hypophosphatemic Rickets / genetics, Wasting Syndrome / diagnosis, Familial Hypophosphatemic Rickets/diagnosis, Osteoarthritis/metabolism, 618.97, Endocrinology, Laboratory medicine & medical technology, Wasting Syndrome/diagnosis, Osteoarthritis / genetics, Wasting Syndrome / genetics, Human health sciences, [SDV.MHEP.EM] Life Sciences [q-bio]/Human health and pathology/Endocrinology and metabolism, 0303 health sciences, Familial Hypophosphatemic Rickets/drug therapy, Osteoarthritis/genetics, Familial Hypophosphatemic Rickets/genetics, [SDV.MHEP.EM]Life Sciences [q-bio]/Human health and pathology/Endocrinology and metabolism, Wasting Syndrome/drug therapy, 3. Good health, Wasting Syndrome/genetics, Médecine de laboratoire & technologie médicale, Rhumatologie, Wasting Syndrome / drug therapy, Familial Hypophosphatemic Rickets, Familial Hypophosphatemic Rickets / drug therapy, Adult, Public health, health care sciences & services, Familial Hypophosphatemic Rickets / diagnosis, Osteoarthritis/diagnosis, Sciences de la santé humaine, Santé publique, services médicaux & soins de santé, Phosphates, 03 medical and health sciences, Rheumatology, Osteoarthritis, Osteoarthritis/drug therapy, Animals, Humans, Wasting Syndrome / metabolism, Osteoarthritis / drug therapy, Wasting Syndrome, Fibroblast Growth Factor-23 / metabolism, Familial Hypophosphatemic Rickets/metabolism, Osteoarthritis / diagnosis, Osteoarthritis / metabolism, Familial Hypophosphatemic Rickets / metabolism, Wasting Syndrome/metabolism, Fibroblast Growth Factors, Fibroblast Growth Factor-23, Quality of Life

Περιγραφή αρχείου: application/pdf

Σύνδεσμος πρόσβασης: https://pubmed.ncbi.nlm.nih.gov/35484227
https://ora.ox.ac.uk/objects/uuid:35ca8364-2c72-47a2-abbd-08054a2631dd
https://doi.org/10.1038/s41574-022-00662-x
https://hdl.handle.net/2268/291983
https://doi.org/10.1038/s41574-022-00662-x
https://archive-ouverte.unige.ch/unige:163101
https://doi.org/10.1038/s41574-022-00662-x
https://hdl.handle.net/20.500.14802/22999

ShcA promotes chondrocyte hypertrophic commitment and osteoarthritis in mice through RunX2 nuclear translocation and YAP1 inactivation

Συγγραφείς: Abou-Jaoude, A., Courtes, M., Badique, L., Elhaj Mahmoud, D., Abboud, C., Mlih, M., Justiniano, H., Milbach, M., Lambert, M., Lemle, A., Awan, S., Terrand, J., Niemeier, A., Barbero, A., Houard, X., Boucher, P., Matz, R.L.

Συνεισφορές: univOAK, Archive ouverte

Πηγή: Osteoarthritis and Cartilage. 30:1365-1375

Θεματικοί όροι: Male, Src Homology 2 Domain-Containing, Transforming Protein 1, ShcA, Cell Differentiation/genetics, Transcription Factors/genetics, Biomedical Engineering, Core Binding Factor Alpha 1 Subunit, Biochimie, biophysique & biologie moléculaire, Osteoarthritis/metabolism, Core Binding Factor Alpha 1 Subunit/genetics, Mice, Chondrocytes, Rheumatology, Collagen/metabolism, Osteoarthritis, Animals, Orthopedics and Sports Medicine, Sciences du Vivant [q-bio]/Immunologie, Shc1 protein, mouse, Endochondral ossification, Chondrocytes/metabolism, Cell Differentiation, YAP-Signaling Proteins, Hypertrophy, Chondrocyte hypertrophy, Life sciences, [SDV] Life Sciences [q-bio], Runx2 protein, mouse, Sciences du vivant, Collagen, Yap1 protein, mouse, Biochemistry, biophysics & molecular biology, Transcription Factors

Περιγραφή αρχείου: application/pdf

Σύνδεσμος πρόσβασης: https://pubmed.ncbi.nlm.nih.gov/35840017
https://hal.sorbonne-universite.fr/hal-03986285v1/document
https://doi.org/10.1016/j.joca.2022.07.001
https://hal.sorbonne-universite.fr/hal-03986285v1
https://linkinghub.elsevier.com/retrieve/pii/S1063458422007919

Development of human cartilage circadian rhythm in a stem cell-chondrogenesis model

Συγγραφείς: Naven, MA, Zeef, LAH, Li, S, Humphreys, PA, Smith, CA, Pathiranage, D, Cain, S, Woods, S, Bates, N, Au, M, Wen, C, Kimber, SJ, Meng, QJ

Συνεισφορές: Department of Biomedical Engineering

Πηγή: Theranostics
Naven, M A, Zeef, L A H, Li, S, Humphreys, P A, Smith, C A, Pathiranage, D, Cain, S, Woods, S, Bates, N, Au, M, Wen, C, Kimber, S J & Meng, Q-J 2022, 'Development of human cartilage circadian rhythm in a stem cell-chondrogenesis model', Theranostics, vol. 12, no. 9, pp. 3963-3976. https://doi.org/10.7150/THNO.70893
Naven, M, Zeef, L, Li, S, Humphreys, P, Smith, C, Pathiranage, D, Cain, S, Woods, S, Bates, N, Au, M, Wen, C, Kimber, S & Meng, Q-J 2022, 'Development of human cartilage circadian rhythm in a stem cell-chondrogenesis model', Theranostics, vol. 12, no. 8, pp. 3963-3976. https://doi.org/10.7150/thno.70893

Θεματικοί όροι: Cartilage, Articular, 0301 basic medicine, Circadian rhythm, Human Embryonic Stem Cells, Human stem cells, Human Embryonic Stem Cells/metabolism, Cell Differentiation, Development, Osteoarthritis/metabolism, Circadian Rhythm, Articular/metabolism, Mice, 03 medical and health sciences, Cartilage, Cartilage, Articular/metabolism, Osteoarthritis, Animals, Humans, Chondrogenesis/genetics, Chondrogenesis, Research Paper

Περιγραφή αρχείου: application/pdf

Σύνδεσμος πρόσβασης: https://pubmed.ncbi.nlm.nih.gov/35664072
https://europepmc.org/articles/PMC9131279
https://research-information.bris.ac.uk/ws/files/329964126/Full_text_PDF_final_published_version_.pdf
https://research-information.bris.ac.uk/en/publications/89deef4b-aff7-4345-ba01-ffc2879a8d5c
https://hdl.handle.net/1983/89deef4b-aff7-4345-ba01-ffc2879a8d5c
https://doi.org/10.7150/THNO.70893

Anti-aging effect of extracellular vesicles from mesenchymal stromal cells on senescence-induced chondrocytes in osteoarthritis

Συγγραφείς: Boulestreau, Jérémy, Maumus, Marie, Minani, Giuliana, Bertolino, Jorgensen, Christian, Noël, Danièle

Συνεισφορές: Cellules Souches, Plasticité Cellulaire, Médecine Régénératrice et Immunothérapies (IRMB), Centre Hospitalier Régional Universitaire Montpellier (CHRU Montpellier)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Montpellier (UM), Service de Rhumatologie CHU de Montpellier, CHU Montpellier, FOREUM Foundation for Research in Rheumatology, ANR-22-PEBI-0013,STROMAEV,From engineering of iPS-derived mesenchymal stromal cell-derived extracellular vesicles to clinical translation(2022), ANR-22-AIBB-0007,OBBI,Occitanie Biotherapy-Bioproduction Integrator : Intégrateur de Bioproduction de Vésicules Extracellulaires et d'Organoïdes en Occitanie(2022), ANR-11-INBS-0005,ECELLFRANCE,Développement d'une Plateforme Nationale pour la médecine régénératrice(2011)

Πηγή: EISSN: 1945-4589 ; Aging ; https://inserm.hal.science/inserm-04888483 ; Aging, 2024, 16 (21), pp.13252-13270. ⟨10.18632/aging.206158⟩

Θεματικοί όροι: osteoarthritis, aging, senescence, extracellular vesicle, mesenchymal stromal cell, regenerative medicine, MESH: Animals, MESH: Cells, Cultured, MESH: Mesenchymal Stem Cells* / metabolism, MESH: Mice, MESH: Osteoarthritis* / metabolism, MESH: Osteoarthritis* / therapy, MESH: Oxidative Stress / drug effects, MESH: Senescence-Associated Secretory Phenotype, MESH: Cellular Senescence, MESH: Chondrocytes* / metabolism, MESH: DNA Damage, MESH: Disease Models, Animal, MESH: Extracellular Vesicles* / metabolism, MESH: Extracellular Vesicles* / transplantation, MESH: Humans, MESH: Male, [SDV.MHEP.RSOA]Life Sciences [q-bio]/Human health and pathology/Rhumatology and musculoskeletal system

Relation: info:eu-repo/semantics/altIdentifier/pmid/39578049; PUBMED: 39578049; PUBMEDCENTRAL: PMC11719114

Διαθεσιμότητα: https://inserm.hal.science/inserm-04888483
https://inserm.hal.science/inserm-04888483v1/document
https://inserm.hal.science/inserm-04888483v1/file/2024-aging-J%C3%A9r%C3%A9my.pdf
https://doi.org/10.18632/aging.206158

Subchondral bone microarchitecture and mineral density in human osteoarthritis and osteoporosis: A regional and compartmental analysis: A regional and compartmental analysis

Συγγραφείς: Yunfei Li, Yulia Liem, Enrico Dall'Ara, Niall Sullivan, Haroon Ahmed, Ashley Blom, Mohammed Sharif

Πηγή: Li, Y, Liem, Y, Dall'Ara, E, Sullivan, N, Ahmed, H, Blom, A W & Sharif, M 2021, 'Subchondral bone microarchitecture and mineral density inhuman osteoarthritis and osteoporosis : A regional and compartmental analysis', Journal of Orthopaedic Research, vol. 39, no. 12, pp. 2568-2580. https://doi.org/10.1002/jor.25018
Li, Y, Liem, Y, Dall'Ara, E, Sullivan, N, Ahmed, H, Blom, A & Sharif, M 2021, 'Subchondral bone microarchitecture and mineral density in human osteoarthritis and osteoporosis : A regional and compartmental analysis', Journal of orthopaedic research : official publication of the Orthopaedic Research Society, vol. 39, no. 12, pp. 2568-2580. https://doi.org/10.1002/jor.25018

Θεματικοί όροι: Cartilage, Articular, 0301 basic medicine, subchondral bone, Cartilage Degeneration, Femur Head/diagnostic imaging, Osteoarthritis/metabolism, 03 medical and health sciences, 0302 clinical medicine, Bone Density, Osteoarthritis, Humans, Subchondral Bone, Osteoporosis/diagnostic imaging, Minerals, Femur Head, X-Ray Microtomography, cartilage degeneration, osteoporosis, Articular/metabolism, osteoarthritis, Cartilage, Cartilage, Articular/metabolism, Mineral Density, Osteoporosis, mineral density, Cartilage Diseases

Περιγραφή αρχείου: application/pdf

Σύνδεσμος πρόσβασης: https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/jor.25018
https://pubmed.ncbi.nlm.nih.gov/33751647
https://research-information.bris.ac.uk/ws/files/274126361/jor.25018.pdf
https://research-information.bris.ac.uk/en/publications/c9603194-14bd-4353-ad21-dda77eab9a7b
https://doi.org/10.1002/jor.25018
https://hdl.handle.net/1983/c9603194-14bd-4353-ad21-dda77eab9a7b
https://eprints.whiterose.ac.uk/id/eprint/172372/

Intergenerational Transmission of Diet‐Induced Obesity, Metabolic Imbalance, and Osteoarthritis in Mice

Συγγραφείς: Natalia S. Harasymowicz, Yun‐Rak Choi, Chia‐Lung Wu, Leanne Iannucci, Ruhang Tang, Farshid Guilak

Συνεισφορές: Natalia S Harasymowicz, Yun-Rak Choi, Chia-Lung Wu, Leanne Iannucci, Ruhang Tang, Farshid Guilak, Choi, Yun Rak

Πηγή: Arthritis & Rheumatology. 72:632-644

Θεματικοί όροι: Inflammation, Male, 0301 basic medicine, 2. Zero hunger, 0303 health sciences, Inflammation / metabolism, Osteoarthritis / genetics, Osteoarthritis / metabolism, Diet, High-Fat, Weight Gain, Diet, 3. Good health, High-Fat, Mice, 03 medical and health sciences, Adipose Tissue, Obesity / metabolism, Osteoarthritis, Adipose Tissue / metabolism, Animals, Female, Obesity, Weight Gain / genetics, Obesity / genetics

Σύνδεσμος πρόσβασης: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7113102
https://pubmed.ncbi.nlm.nih.gov/31646754

Blockade of Activin Receptor IIB Protects Arthritis Pathogenesis by Non‐Amplification of Activin A‐ACVR2B‐NOX4 Axis Pathway

Συγγραφείς: Jimin Jeon, Hyemi Lee, Min‐Seung Jeon, Seok‐Jung Kim, Cham Choi, Ki Woo Kim, Dong Joo Yang, Sangho Lee, Yong‐Soo Bae, Won Il Choi, Juyeon Jung, Seong‐il Eyun, Siyoung Yang

Συνεισφορές: Jimin Jeon, Hyemi Lee, Min-Seung Jeon, Seok-Jung Kim, Cham Choi, Ki Woo Kim, Dong Joo Yang, Sangho Lee, Yong-Soo Bae, Won Il Choi, Juyeon Jung, Seong-Il Eyun, Siyoung Yang, kim, KiWoo

Πηγή: Adv Sci (Weinh)
Advanced Science, Vol 10, Iss 14, Pp n/a-n/a (2023)

Θεματικοί όροι: NADPH Oxidase 4 / metabolism, mouse model, Science, Activin Receptors, Activin Receptors, Type II, Chondrocytes* / pathology, ACVR2B assembly, Ligands, druggable target, 3. Good health, Activins, Activin Receptors / metabolism, human OA cartilage, Mice, Osteoarthritis* / metabolism, Chondrocytes, NADPH Oxidase 4, Chondrocytes* / metabolism, Osteoarthritis, Animals, arthritis treatment, Research Articles

Σύνδεσμος πρόσβασης: https://pubmed.ncbi.nlm.nih.gov/36950748
https://doaj.org/article/27d8c16919974a4aa38255628bd3002c

ShcA promotes chondrocyte hypertrophic commitment and osteoarthritis in mice through RunX2 nuclear translocation and YAP1 inactivation.

Συγγραφείς: Abou-Jaoude, A, Courtes, M, Badique, L, Elhaj Mahmoud, D, Abboud, Clauda, Mlih, M, Justiniano, H, Milbach, M, Lambert, M, Lemle, A, Awan, S, Terrand, J, Niemeier, A, Barbero, A, Houard, X, Boucher, P, Matz, R L

Πηγή: Osteoarthritis and Cartilage, 30 (10), 1365 - 1375 (2022-10)

Θεματικοί όροι: Chondrocyte hypertrophy, Endochondral ossification, Osteoarthritis, ShcA, Core Binding Factor Alpha 1 Subunit, Runx2 protein, mouse, Shc1 protein, mouse, Src Homology 2 Domain-Containing, Transforming Protein 1, Transcription Factors, YAP-Signaling Proteins, Yap1 protein, mouse, Collagen, Animals, Cell Differentiation/genetics, Collagen/metabolism, Core Binding Factor Alpha 1 Subunit/genetics, Hypertrophy, Male, Mice, Transcription Factors/genetics, Chondrocytes/metabolism, Osteoarthritis/metabolism, Cell Differentiation, Chondrocytes, Rheumatology, Biomedical Engineering, Orthopedics and Sports Medicine, Life sciences, Biochemistry, biophysics & molecular biology, Sciences du vivant, Biochimie, biophysique & biologie moléculaire

Relation: https://api.elsevier.com/content/article/PII:S1063458422007919?httpAccept=text/xml; urn:issn:1063-4584; urn:issn:1522-9653

Σύνδεσμος πρόσβασης: https://orbi.uliege.be/handle/2268/303072

Assessment of disease activity in patients with rheumatoid arthritis using plasma tumour M2-pyruvate kinase test

Συνεισφορές: Sung Soo Ahn, Hye Min Kim, Younhee Park, Kim, Hye Min

Θεματικοί όροι: Arthritis, Rheumatoid* / diagnosis, Rheumatoid* / pathology, Blood Sedimentation, C-Reactive Protein / metabolism, Humans, Neoplasms / diagnosis, Neoplasms / pathology, Osteoarthritis* / diagnosis, Osteoarthritis* / metabolism, Osteoarthritis* / pathology, Pyruvate Kinase, Synovial Membrane / pathology, biomarker, disease activity, predictor, rheumatoid arthritis, tumour M2-pyruvate kinase

Relation: FRONTIERS IN IMMUNOLOGY; J03075; https://ir.ymlib.yonsei.ac.kr/handle/22282913/191814; T202203321

Διαθεσιμότητα: https://ir.ymlib.yonsei.ac.kr/handle/22282913/191814
https://doi.org/10.3389/fimmu.2022.901555

Fibrin deposition associates with cartilage degeneration in arthritis

Συγγραφείς: Ehirchiou, D., Omoumi, P., So, A., Busso, N.

Πηγή: EBioMedicine, vol. 81, pp. 104081

Θεματικοί όροι: Animals, Arthritis, Rheumatoid/metabolism, Cartilage/metabolism, Chondrocytes/metabolism, Fibrin/metabolism, Fibrinogen/genetics, Fibrinogen/metabolism, Humans, Mice, Osteoarthritis/genetics, Osteoarthritis/metabolism, Synovial Membrane, Arthritis, Calcification, Cartilage degradation, Chondro-synovial adhesion, Fibrin, Fibrinogen

Περιγραφή αρχείου: application/pdf

Σύνδεσμος πρόσβασης: https://serval.unil.ch/notice/serval:BIB_51597531A1D0
https://serval.unil.ch/resource/serval:BIB_51597531A1D0.P001/REF.pdf
http://nbn-resolving.org/urn/resolver.pl?urn=urn:nbn:ch:serval-BIB_51597531A1D03

Occurrence of food borne pathogen in some types of soft cheese in local market

Συγγραφείς: Benha University, Egyptian Government, Egyptian Universities Network, Harvard University, Russian Research Institute for Phytopathology, Indian Navy, University of Iranians, Healthcare over Internet Protocol Community Interest Company (United Kingdom), InternetSpeech (United States), Keys for Networking

Θεματικοί όροι: Food preservation, Nanotechnology/standards, Bacterial Zoonoses, Secrets, Epidemiology, Behavioural ecology, Skin Diseases, Bacterial/classification, Television/trends, Myositis/classification, Polymerase Chain Reaction, Pulmonary Arterial Hypertension/epidemiology, Osteoarthritis/metabolism, Breast Diseases, Zoonoses/enzymology, Population ecology, Barth Syndrome/epidemiology, Bacteria morphology and physiology, Nanotechnology, Plant ecology, Polymerase Chain Reaction/ethics, Skin Diseases, Bacterial/etiology, Electron Microscope Tomography/veterinary, FOS: Media and communications, Multiplex Polymerase Chain Reaction/classification, Vaccination, Microscopy, Electron/standards, Satellite Communications/ethics, Vaccination/instrumentation, Immunologic Surveillance/immunology, Metals, Light, Hepatic Infarction, Zoonoses/diagnosis, Skin Diseases, Bacterial/epidemiology, Cardiovascular diseases, PCR, Clinical Alarms, Cheese/history, Cheese/statistics & numerical data, Protein Corona, Gene Expression Regulation, Bacterial/radiation effects, Nanotechnology/history, Molecular Biology/standards, Cerebral Arterial Diseases/epidemiology, Zoonoses/embryology, Mycology/instrumentation, Multiplex Polymerase Chain Reaction/methods, Electron Microscope Tomography/instrumentation, Constriction, Pathologic/pathology, Satellite Communications/economics, Retinal Arterial Macroaneurysm/epidemiology, Mycology/economics, Chemical, Electron Microscope Tomography/psychology, Metals/history, Osteoarthritis/microbiology, Myositis/metabolism, Media Exposure, Milk/parasitology, Mass Media, Genome, Bacterial/radiation effects, Milk/microbiology, Media Exposure/standards, FOS: Nanotechnology, Cheese/poisoning, Hepatic Infarction/metabolism, Bacteria, Metals/poisoning, Food Inspection, Communications, Culture Media, Neuroinflammatory Diseases, Milk/classification, Transformation, Bacterial, Bacteriology/ethics, Sexually Transmitted Diseases, Bacterial, Cheese/virology, Abetalipoproteinemia/pathology, Vaccination Coverage, Immunologic Capping/immunology, Nanotechnology/trends, Vaccination/history, Crystalluria/epidemiology, Ankyloglossia/epidemiology, Immunologic Factors/immunology, Skin Diseases, Bacterial/diagnosis, Electron Microscope Tomography/mortality, Multiplex Polymerase Chain Reaction/ethics, Ecology, Forensic Sciences, Vaginosis, Bacterial, Transition metals, Molecular Biology/trends, Osteoarthritis, Knee, Scientific ecology, Metals/metabolism, Luciferases, Bacterial, Communications Media/trends, Meningitis, Bacterial/epidemiology, Nystagmus, Pathologic/pathology, Forensic sciences, Molecular Biology/legislation & jurisprudence, Ciliopathies/epidemiology, Polymerase Chain Reaction/veterinary, Vaccination/ethics, Osteoarthritis/urine, Mass Vaccination, Meningitis, Bacterial, Metals, Heavy, Immunologic Deficiency Syndromes/immunology, Bacterial Lysates, Bacterial epidemics, Milk/toxicity, Orbital Myositis, Bacteriology/classification, Gene Expression Regulation, Bacterial/ethics, Defoliants, Chemical/chemical synthesis, Skin Diseases, Bacterial/immunology, Clinical Deterioration, Communications Media, Abscess/pathology, Anti-Vaccination Movement, Teratozoospermia/epidemiology, Otitis Media, Ethics, Clinical, Corona, Arterial Occlusive Diseases/epidemiology, Satellite Communications/instrumentation, Electron Microscope Tomography/statistics & numerical data, Electron Microscope Tomography/ethics, Polymerase Chain Reaction/methods, Electron Microscope Tomography/history, Molecular Biology/ethics, Bacteriology/trends, Antibacterial drugs, Gram-Positive Bacterial Infections/epidemiology, Satellite Communications/legislation & jurisprudence, Colonic Diseases, Zoonosis, Ecology/economics, Clinical Protocols, Molecular Biology/history, Cheese/radiation effects, Nanotechnology/statistics & numerical data, Internal Medicine/standards, Insects reservoirs, Communications Media/legislation & jurisprudence, Skin Diseases, Bacterial/virology, Bacteriology/economics, Molecular Biology/education, Hepatic Infarction/nursing, Communications Media/supply & distribution, (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride, Multiplex Polymerase Chain Reaction/standards, Media Exposure/education, Communications Media/ethics, Multiplex Polymerase Chain Reaction/history, Bacterial Vaccines, Phycology, Convenience food, Milk/cytology, Electron Microscope Tomography/economics, Farms, Bunion/epidemiology, Hepatic Infarction/enzymology, Cattle Diseases, Cheese/adverse effects, Food Contamination, Food technology, Cytotoxicity, Immunologic/immunology, Electron Microscope Tomography/trends, Endocarditis, Subacute Bacterial/epidemiology, Genome, Bacterial/physiology, Contrast Media/metabolism, Food allergy, Pneumonia, Bacterial, Myositis/blood, Skin Diseases, Bacterial/economics, Vaccination/methods, Communications Media/standards, Bacterial growth, Laboratory Chemicals/chemical synthesis, Antibiotic Prophylaxis/history, Prophylaxis, Farms/ethics, Bacteriology/standards, Quantum computers, Mycology/ethics, Tympanosclerosis/epidemiology, Porphyrias, Hepatic, Myositis/history, Zoonoses/blood, Milk Banks, Inorganic Chemicals, Clinical medicine, Gingival Diseases, Bone Demineralization, Pathologic/pathology, Clinical Medicine, Zoonoses/immunology, Mass media, Satellite Communications/classification, Molecular Biology/organization & administration, Eye Infections, Bacterial/epidemiology, Renal faliure, Molecular biology, Osteoarthritis/complications, Zoonoses/metabolism, Neovascularization, Pathologic/pathology, Portoenterostomy, Hepatic, Microscopy, Electron/ethics, Bacterial pyelonephritis, Animal Diseases, Polymerase Chain Reaction/history, Zoonoses, Electron Microscope Tomography/classification, Skin Diseases, Bacterial/therapy, Mandatory Vaccination, Farms/economics, Myositis/urine, Bacterial Shedding, Kidney diseases, Nanotechnology/organization & administration, Clinical Clerkship, Milk/immunology, Milk/metabolism, Skin Diseases, Bacterial/genetics, Skin Diseases, Bacterial/congenital, Mycology/history, Satellite Communications, Zoonoses/complications, Clinical neurology, Bacterial Zoonoses/epidemiology, Gram-Negative Bacterial Infections/epidemiology, Myositis/enzymology, Gene Expression Regulation, Bacterial/physiology, Clinical Competence, Bacteriology/organization & administration, Echinococcosis, Hepatic, Metals/economics, Bacterial diseases, Landscape ecology, Computers/classification, Gallbladder Diseases, Mycology, Inorganic Chemicals/chemical synthesis, Metals/agonists, Ototoxicity/epidemiology, Molecular biology parameters, Computers/trends, Polymerase Chain Reaction/economics, Mycology/legislation & jurisprudence, Zoonoses/history, Vaccinations, Mycology/organization & administration, Myositis, Nanotechnology/instrumentation, Computers, FOS: Clinical medicine, Vaccination/classification, Skin Diseases, Bacterial/physiopathology, Inorganic Chemicals/pharmacology, Antibiotic Prophylaxis, Zoonoses/etiology, Microscopy, Electron, Zoonoses/mortality, Milk Hypersensitivity, Cytology, Temefos/pharmacology, Metals/standards, Molecular Biology/classification, Electron Microscope Tomography, Psychology, Clinical, Metals/blood, Hepatic Infarction/rehabilitation, Genome, Bacterial/immunology, Media and communications, Satellite Communications/organization & administration, Osteoarthritis/etiology, Genome, Bacterial/drug effects, Hepatic Artery, Acari/microbiology, Metals/chemistry, Trophic ecology, Cheese, Media Exposure/economics, Canaliculitis/epidemiology, Osteoarthritis/surgery, Skin Diseases, Bacterial/nursing, Vaccination/trends, Skin Diseases, Bacterial/ethnology, Oncology, Computers, Analog, Quarantine, Skin Diseases, Bacterial/transmission, Eyelid Diseases, Vaccination Refusal/history, Inorganic Chemicals/agonists, Breast milk, Sexually Transmitted Diseases, Bacterial/epidemiology, Mycology/classification, Communications Media/classification, Zoonoses/parasitology, Chemicals act, Microbiology, Corona viruses, Vaccination/psychology, Bacterial Proteins, Clinical waste, Skin Diseases, Bacterial/parasitology, Human ecology, Osteoarthritis, Earth epidemiology, Food hygiene, Milk/poisoning, Noncommunicable Diseases, Polymerase Chain Reaction/instrumentation, Molecular Biology, Abomasum/microbiology, Farms Diseases, Metals, Alkali, Metals/immunology, Milk Sickness, Endocarditis, Bacterial, Zoonoses/transmission, Zoonoses/economics, Receptors, Immunologic/immunology, Hepatic Encephalopathy, Osteoarthritis/embryology, Ecology/ethics, Molecular Biology/methods, Food Preservatives, Molecular Biology/statistics & numerical data, Osteoarthritis/epidemiology, Parasitology, Hepatic Infarction/classification, Social Media, Demyelinating Diseases, Food Safety, Alkali metals, Zoonoses/radiotherapy, Mycology/education, Cheese/standards, Television/standards, Nanotechnology/legislation & jurisprudence, Satellite Communications/standards, Communications Media/economics, Internal Medicine/ethics, Food science, Myositis/etiology, Conjunctivitis, Bacterial, Clinical insects epidemiology, Functional Food, Zoonoses/ethnology, Hepatic Infarction/radiotherapy, Myositis/mortality, Protein Corona/analysis, Osteoarthritis/therapy, Organic Chemicals, Vaccination/economics, Zoonoses/genetics, Myositis/virology, Reverse Transcriptase Polymerase Chain Reaction, Electron Microscope Tomography/methods, Milk/economics, Vaccination/nursing, Bacteriology/statistics & numerical data, Bacterial hepatitis, Television/classification, Computers, Mainframe, Antibodies, Bacterial, Internal Medicine/economics, Pathologic Processes/pathology, Ecology/instrumentation, Television/ethics, Satellite Communications/trends, Genital Diseases, Metals, Immunologic Memory/immunology, Food Irradiation, Food, Organic, Mycology/standards, Hepatic Infarction/etiology, Metals/classification, Myositis/microbiology, Central Nervous System Bacterial Infections/epidemiology, Osteoarthritis/diagnosis, Vaccination/veterinary, Metals/toxicity, Nanotechnology/economics, Foot Diseases, Myositis/congenital, Protein Corona/immunology, Bacteriology/legislation & jurisprudence, Food Preferences, Hepatic Infarction/embryology, Mycology/methods, Gene Expression Regulation, Bacterial/immunology, Electron microscopy, Tuberculosis, Hepatic, Hepatic Insufficiency, Transplantation Immunology/immunology, Cheese/toxicity, Clinical microbiology, Vaccination/mortality, Gene Expression Regulation, Bacterial/drug effects, Clinical Relevance, Milk, Human, Osteoarthritis/pathology, Food waste, Bacteriology, Bacteriology/education, Molecular Biology/economics, Vaginosis, Bacterial/epidemiology, Skin Diseases, Bacterial, Jejunal Diseases, Nanotechnology/classification, Forensic Medicine, Organic Chemicals/chemical synthesis, Polymerase Chain Reaction/trends, Osteoarthritis/economics, Osteoarthritis/psychology, Bacteriology/instrumentation, Multiplex Polymerase Chain Reaction/economics, Forensic Anthropology, Audiovisual media, Media Exposure/ethics, Contrast Media, Microscopy, Electron/methods, Bacterial Adhesion, Bacterial Infections and Mycoses/epidemiology, Acanthocytes/microbiology, Nanotechnology/ethics, Cheese/microbiology, Pathology, Polymerase Chain Reaction/standards, Acantholysis/pathology, Myositis/parasitology, Forensic Pathology, Spores, Bacterial, Frailty/epidemiology, Polysaccharides, Bacterial, Computers/standards, Food Services, Myositis/nursing, Multiplex Polymerase Chain Reaction/veterinary, Milk, Nanotechnology/education, Osteoarthritis/immunology, Adnexal Diseases, Milk/physiology, Infectious diseases, Television, Urogenital Diseases, Metals/urine, Decalcification, Pathologic/pathology, Media, Internal Medicine/classification, Myositis/embryology, Suppressor Factors, Immunologic/immunology, Computers/ethics, Immunology, Cheese/supply & distribution, Press release, Myositis/diagnosis, Hepatic Veins, Thromboinflammation/epidemiology, Molecular Biology/instrumentation, Food packaging, Zoonoses/classification, Mycology/statistics & numerical data, Milk/enzymology, Milk/chemistry, Endocarditis, Bacterial/epidemiology, Clinical Governance, Skin Diseases, Bacterial/embryology, Protein Corona/chemistry, Bacterial epidemiology, Diverticular Diseases, Pharmacology, Gene Expression Regulation, Bacterial/genetics, Mythology, Peripheral Arterial Disease/epidemiology, Computers/economics, Osteoarthritis/mortality, High primates reservoirs, Milk/history, Food, Chemistry, Clinical, FOS: Biological sciences, Applied ecology, Myositis/ethnology, Inorganic Chemicals/economics, Rhinorrhea/epidemiology, Bacterial Infections/epidemiology, Laboratories, Clinical, Osteoarthritis/veterinary, Osteoarthritis/congenital, Mycology/trends, Electron Microscope Tomography/standards, Myositis/immunology, Skin Diseases, Bacterial/microbiology, Polymerase Chain Reaction/classification, Bacterial morphology, Skin Diseases, Bacterial/urine, Clinical Reasoning, Bacteriology/history, Conjunctival Diseases, Cheese/parasitology, Pneumonia, Bacterial/epidemiology, Bacterial genotypes, Vaccination Refusal, Conjunctivitis, Bacterial/epidemiology, Hepatic Infarction/immunology, Multiplex Polymerase Chain Reaction/instrumentation, Hepatic Infarction/ethnology, Osteoarthritis/parasitology, Abetalipoproteinemia/epidemiology, Internal medicine, Pathology, Clinical, Television/history, Food Fussiness, Press, Communications Media/history, Cheese/classification, Metals/pharmacokinetics, Pharmacology, Clinical, Chemicals, Anatomy, Tunica Media, Cheese/analysis, Histology, Cheese/economics, Histopathology, Bacterial genome, Nanotechnology/methods, Satellite Communications/history, Marine ecology, Forensic Imaging, Forensic Toxicology, Electron Microscope Tomography/nursing, Laboratory Chemicals, Vaccination/standards, Electron Microscope Tomography/adverse effects, MINOCA/epidemiology, Agricultural ecology, Internal Medicine, Nutrition, Antigens, Bacterial, Clinical Audit, Genome, Bacterial/genetics, Gene Expression Regulation, Bacterial, Hepatic Infarction/diagnosis, Metals/analysis, Food Insecurity, Myositis Ossificans, Dilatation, Pathologic/pathology, Vaccination Hesitancy, Multiplex Polymerase Chain Reaction, Genome, Bacterial