O-linked glycan-dependent gating of TPC2 controls lysosomal excitability and organelle remodeling

Συγγραφείς: Alice Lin, Neng-Yu Lin, Marco Keller, Ramona Schütz, Yi-Zhen Wu, William Burton, Novelyn Putri Kinanti, Chi-Yuan Yao, Nicole Urban, Ya-Wen Liu, Franz Bracher, Antony Galione, Hao-Jen Hsu, Ching-Ying Kuo, Cheng-Chang Chen

Πηγή: Nature Communications, Vol 17, Iss 1 (2026)

Θεματικοί όροι: Science

Περιγραφή αρχείου: electronic resource

Relation: https://doaj.org/toc/2041-1723

Σύνδεσμος πρόσβασης: https://doaj.org/article/6c8a4474f3874b53af597b5a8609c0c5

O-GlcNAcylation expression predicts a favorable prognosis and mitigates malignant phenotypes via MYCN suppression in neuroblastoma

Συγγραφείς: Neng-Yu Lin, Hsiu-Hao Chang, Chia-Yeh Hsieh, Hsiu-Ling Chang, Wan-Ling Ho, Yen-Lin Liu, Pei-Yi Wu, Chi-Tai Yeh, Min-Chuan Huang, Wen-Ming Hsu

Πηγή: Molecular and Cellular Pediatrics, Vol 13, Iss 1 (2026)

Θεματικοί όροι: O-GlcNAc, Neuroblastoma, MYCN, GSK3β, Pediatrics, RJ1-570

Περιγραφή αρχείου: electronic resource

Relation: https://doaj.org/toc/2194-7791

Σύνδεσμος πρόσβασης: https://doaj.org/article/a07928151dfa4ba4b0bca7c0fbe51f83

The branched N-glycan of PD-L1 predicts immunotherapy responses in patients with recurrent/metastatic HNSCC

Συγγραφείς: Huai-Cheng Huang, Yen-Lin Huang, Yi-Ju Chen, Hsin-Yi Wu, Chia-Lang Hsu, Hsiang-Fong Kao, Bin-Chi Liao, Min-Shu Hsieh, Neng-Yu Lin, Yu-Hao Liao, Hsin-Lin Chen, Chun-Nan Chen, Tseng-Cheng Chen, Cheng-Ping Wang, Tsung-Lin Yang, Min-Chuan Huang, Mei-Chun Lin, Pei-Jen Lou

Πηγή: Oncogenesis, Vol 13, Iss 1, Pp 1-10 (2024)

Θεματικοί όροι: Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

Περιγραφή αρχείου: electronic resource

Relation: https://doaj.org/toc/2157-9024

Σύνδεσμος πρόσβασης: https://doaj.org/article/70de69921c8547aeb318aa0db5ded965

Targeting tumor O‐glycosylation modulates cancer–immune‐cell crosstalk and enhances anti‐PD‐1 immunotherapy in head and neck cancer

Συγγραφείς: Mei‐Chun Lin, Ya‐Ting Chuang, Hsin‐Yi Wu, Chia‐Lang Hsu, Neng‐Yu Lin, Min‐Chuan Huang, Pei‐Jen Lou

Πηγή: Molecular Oncology, Vol 18, Iss 2, Pp 350-368 (2024)

Θεματικοί όροι: core 1 β1,3‐galactosyltransferase, head and neck cancer, IL‐6, immune checkpoint inhibitor, itraconazole, O‐glycosylation, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

Περιγραφή αρχείου: electronic resource

Relation: https://doaj.org/toc/1574-7891; https://doaj.org/toc/1878-0261

Σύνδεσμος πρόσβασης: https://doaj.org/article/e9ed1e8e7af94aa582632080fc33d22f

Noncanonical WNT5A controls the activation of latent TGF-β to drive fibroblast activation and tissue fibrosis

Συγγραφείς: Thuong Trinh-Minh, Chih-Wei Chen, Cuong Tran Manh, Yi-Nan Li, Honglin Zhu, Xiang Zhou, Debomita Chakraborty, Yun Zhang, Simon Rauber, Clara Dees, Neng-Yu Lin, Delf Kah, Richard Gerum, Christina Bergmann, Alexander Kreuter, Christiane Reuter, Florian Groeber-Becker, Beate Eckes, Oliver Distler, Ben Fabry, Andreas Ramming, Alexandra Schambony, Georg Schett, Jörg H.W. Distler

Πηγή: The Journal of Clinical Investigation, Vol 134, Iss 10 (2024)

Θεματικοί όροι: Dermatology, Pulmonology, Medicine

Περιγραφή αρχείου: electronic resource

Relation: https://doaj.org/toc/1558-8238

Σύνδεσμος πρόσβασης: https://doaj.org/article/90215e3007814711a8524fc9ae3c8975

GALNT2 promotes invasiveness of colorectal cancer cells partly through AXL

Συγγραφείς: Ying‐Yu Liao, Ya‐Ting Chuang, Hsuan‐Yu Lin, Neng‐Yu Lin, Tzu‐Wen Hsu, Szu‐Chia Hsieh, Syue‐Ting Chen, Ji‐Shiang Hung, Hung‐Jen Yang, Jin‐Tung Liang, Min‐Chuan Huang, John Huang

Πηγή: Molecular Oncology, Vol 17, Iss 1, Pp 119-133 (2023)

Θεματικοί όροι: AXL, GALNT, glycosylation, invasion, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

Περιγραφή αρχείου: electronic resource

Relation: https://doaj.org/toc/1574-7891; https://doaj.org/toc/1878-0261

Σύνδεσμος πρόσβασης: https://doaj.org/article/7df1b90412ab4d11a81a0359468905a8

Dynamic changes in O-GlcNAcylation regulate osteoclast differentiation and bone loss via nucleoporin 153

Συγγραφείς: Yi-Nan Li, Chih-Wei Chen, Thuong Trinh-Minh, Honglin Zhu, Alexandru-Emil Matei, Andrea-Hermina Györfi, Frederic Kuwert, Philipp Hubel, Xiao Ding, Cuong Tran Manh, Xiaohan Xu, Christoph Liebel, Vladyslav Fedorchenko, Ruifang Liang, Kaiyue Huang, Jens Pfannstiel, Min-Chuan Huang, Neng-Yu Lin, Andreas Ramming, Georg Schett, Jörg H. W. Distler

Πηγή: Bone Research, Vol 10, Iss 1, Pp 1-17 (2022)

Θεματικοί όροι: Biology (General), QH301-705.5, Physiology, QP1-981

Περιγραφή αρχείου: electronic resource

Relation: https://doaj.org/toc/2095-6231

Σύνδεσμος πρόσβασης: https://doaj.org/article/9ac47eda1306433987ca42044a6cf8fb

C1GALT1 expression predicts a favorable prognosis and suppresses malignant phenotypes via TrkA signaling in neuroblastoma

Συγγραφείς: Neng-Yu Lin, Syue-Ting Chen, Hsiu-Ling Chang, Meng-Yao Lu, Yung-Li Yang, Shu-Wei Chou, Dong-Tsamn Lin, Kai-Hsin Lin, Shiann-Tarng Jou, Wen-Ming Hsu, Min-Chuan Huang, Hsiu-Hao Chang

Πηγή: Oncogenesis, Vol 11, Iss 1, Pp 1-9 (2022)

Θεματικοί όροι: Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

Περιγραφή αρχείου: electronic resource

Relation: https://doaj.org/toc/2157-9024

Σύνδεσμος πρόσβασης: https://doaj.org/article/b6694bc2a5e843d1b1d0952aa096ac54

TGFβ promotes fibrosis by MYST1-dependent epigenetic regulation of autophagy

Συγγραφείς: Ariella Zehender, Yi-Nan Li, Neng-Yu Lin, Adrian Stefanica, Julian Nüchel, Chih-Wei Chen, Hsiao-Han Hsu, Honglin Zhu, Xiao Ding, Jingang Huang, Lichong Shen, Andrea-Hermina Györfi, Alina Soare, Simon Rauber, Christina Bergmann, Andreas Ramming, Markus Plomann, Beate Eckes, Georg Schett, Jörg H. W. Distler

Πηγή: Nature Communications, Vol 12, Iss 1, Pp 1-19 (2021)

Θεματικοί όροι: Science

Περιγραφή αρχείου: electronic resource

Relation: https://doaj.org/toc/2041-1723

Σύνδεσμος πρόσβασης: https://doaj.org/article/62b5d5ace81c405bb445c8cf7e9725a7

C1GALT1 expression predicts poor survival in osteosarcoma and is crucial for ABCC1 transporter‐mediated doxorubicin resistance

Συγγραφείς: Chun‐Wei Liu, Jing‐Hui Huang, Hsiu‐Hao Chang, Chia‐Hua Chen, Yi‐Huan Tsai, Wei‐Li Chen, Jung‐An Lin, Hsiu‐Ling Chang, Cheng‐Chang Chen, Mei‐Chun Lin, Min‐Chuan Huang, Neng‐Yu Lin

Πηγή: J Pathol

Θεματικοί όροι: ATP-Binding Cassette, Sub-Family C Proteins, Male, Adult, Osteosarcoma, Antibiotics, Antineoplastic, Bone Neoplasms, Apoptosis, Galactosyltransferases, Gene Expression Regulation, Neoplastic, Mice, Doxorubicin, Drug Resistance, Neoplasm, Cell Line, Tumor, Biomarkers, Tumor, Humans, Animals, Original Article, Female

Σύνδεσμος πρόσβασης: https://pubmed.ncbi.nlm.nih.gov/39844613

Truncation of GalNAc-type O-glycans Suppresses CD44-mediated Osteoclastogenesis and Bone Metastasis in Breast Cancer

Συγγραφείς: Neng-Yu Lin, Jian-Jr Lee, Syue-Ting Chen, Jung-An Lin, Chia-Hsuan Lin, Hsuan-Yu Lin, Yong-Han Su, Cheng-Chang Chen, Mei-Chun Lin, Ching-Ying Kuo, Min-Chuan Huang

Πηγή: Mol Cancer Res

Θεματικοί όροι: Glycosylation, Hyaluronan Receptors, Osteogenesis, Polysaccharides, Humans, Female, Breast Neoplasms, Cancer Genes and Networks, Galactosyltransferases, 3. Good health, Signal Transduction

Σύνδεσμος πρόσβασης: https://pubmed.ncbi.nlm.nih.gov/37040171

Targeting neuroblastoma with 3β,5α-tetrahydrocorticosterone: Activation of aryl hydrocarbon receptor inhibits tumor growth, metastasis, and stemness while promoting neural differentiation

Συγγραφείς: Zhu-Qian Wen, Wen-Ming Hsu, Chien-Chun Chiou, Farhan Azhwin Maulana, Chia-Hwa Chang, Jie-Ming Huang, Zhi-Kai Yu, Chien-Chin Chen, Neng-Yu Lin, Chun-FA. Tsai, Jheng-Siou Lai, Yue-Ling Chen, Pei-Yi Wu

Πηγή: Chemico-Biological Interactions. 421:111780

Θεματικοί όροι: Mice, Nude, Cell Differentiation, Apoptosis, Antineoplastic Agents, Molecular Docking Simulation, Neuroblastoma, Mice, Receptors, Aryl Hydrocarbon, Cell Line, Tumor, Cytochrome P-450 CYP1A1, Humans, Animals, Neoplasm Metastasis, Cell Proliferation

Σύνδεσμος πρόσβασης: https://pubmed.ncbi.nlm.nih.gov/41093127

TMTC1 promotes invasiveness of ovarian cancer cells through integrins β1 and β4

Συγγραφείς: Ting-Chih Yeh, Neng-Yu Lin, Chin-Yu Chiu, Tzu-Wen Hsu, Hsin-Yi Wu, Hsuan-Yu Lin, Chi-Hau Chen, Min-Chuan Huang

Πηγή: Cancer Gene Ther

Θεματικοί όροι: Ovarian Neoplasms, Cell Movement, Cell Line, Tumor, Integrin beta1, Integrin beta4, Cell Adhesion, Humans, Membrane Proteins, Female, Carrier Proteins, Article, 3. Good health

Σύνδεσμος πρόσβασης: https://pubmed.ncbi.nlm.nih.gov/37221403

TRPML2 channel modulation by PI(3,5)P₂ and small-molecule agonists controls endosomal vesicle dynamics

Συγγραφείς: Zi-Qi Gu, Hsuan-Ti Wang, Yanfen Li, Einar Krogsaeter, Alice C. Lin, Jackson Lin, Yi-Shan Liu, Wei-Shuan Lin, William Burton, Mu-Lin Liu, Colin Feldmann, Rachel Tang, Ching-Wen Po, Pei-Shan Hou, Neng-Yu Lin, Jing-Yi Lin, Tai-Ling Chao, Sui-Yuan Chang, Zhuo Yang, Marco Keller, Charlotte Leser, Stefanie Fenske, Franz Bracher, Christian Wahl-Schott, Antony Galione, Yu-Huan Tsai, Christian Grimm, Martin Biel, Cheng-Chang Chen

Πηγή: Biomedicine & Pharmacotherapy. 189:118350

Θεματικοί όροι: Transient Receptor Potential Channels, HEK293 Cells, Phosphatidylinositol Phosphates, rab4 GTP-Binding Proteins, Mutation, Humans, Animals, Endosomes, Lysosomes

Σύνδεσμος πρόσβασης: https://pubmed.ncbi.nlm.nih.gov/40664038

C1GALT1-specific chaperone 1 promotes malignant phenotypes of colon cancer cells

C1GALT1-specificchaperone1促進大腸直腸癌細胞惡性行為

Συγγραφείς: Neng-Yu Lin, 林能裕

Thesis Advisors: Min-Chuan Huang, 黃敏銓

Περιγραφή αρχείου: 42

Διαθεσιμότητα: http://ndltd.ncl.edu.tw/handle/23066551306525752947

Supplementary Figure 1 from Truncation of GalNAc-type O-glycans Suppresses CD44-mediated Osteoclastogenesis and Bone Metastasis in Breast Cancer

Συγγραφείς: Min-Chuan Haung, Ching-Ying Kuo, Mei-Chun Lin, Cheng-Chang Chen, Yong-Han Su, Hsuan-Yu Lin, Chia-Hsuan Lin, Jung-An Lin, Syue-Ting Chen, Jian-Jr Lee, Neng-Yu Lin

Supplementary Figure 3 from Truncation of GalNAc-type O-glycans suppresses CD44-mediated osteoclastogenesis and bone metastasis in breast cancer

Συγγραφείς: Min-Chuan Huang, Ching-Ying Kuo, Mei-Chun Lin, Cheng-Chang Chen, Yong-Han Su, Hsuan-Yu Lin, Chia-Hsuan Lin, Jung-An Lin, Syue-Ting Chen, Jian-Jr Lee, Neng-Yu Lin

Data from Truncation of GalNAc-type O-glycans Suppresses CD44-mediated Osteoclastogenesis and Bone Metastasis in Breast Cancer

Συγγραφείς: Min-Chuan Huang, Ching-Ying Kuo, Mei-Chun Lin, Cheng-Chang Chen, Yong-Han Su, Hsuan-Yu Lin, Chia-Hsuan Lin, Jung-An Lin, Syue-Ting Chen, Jian-Jr Lee, Neng-Yu Lin

Θεματικοί όροι: 3. Good health

Supplementary Figure 2 from Truncation of GalNAc-type O-glycans Suppresses CD44-mediated Osteoclastogenesis and Bone Metastasis in Breast Cancer

Συγγραφείς: Min-Chuan Haung, Ching-Ying Kuo, Mei-Chun Lin, Cheng-Chang Chen, Yong-Han Su, Hsuan-Yu Lin, Chia-Hsuan Lin, Jung-An Lin, Syue-Ting Chen, Jian-Jr Lee, Neng-Yu Lin

Supplementary Table 1 from Truncation of GalNAc-type O-glycans Suppresses CD44-mediated Osteoclastogenesis and Bone Metastasis in Breast Cancer

Συγγραφείς: Min-Chuan Huang, Ching-Ying Kuo, Mei-Chun Lin, Cheng-Chang Chen, Yong-Han Su, Hsuan-Yu Lin, Chia-Hsuan Lin, Jung-An Lin, Syue-Ting Chen, Jian-Jr Lee, Neng-Yu Lin

Θεματικοί όροι: 3. Good health