Hippocampal hub failure is linked to long-term memory impairment in anti-NMDA-receptor encephalitis - Insights from structural connectome graph theoretical network analysis

Authors: André Hechler, Joseph Kuchling, Leonie Müller-Jensen, Johanna Klag, Friedemann Paul, Harald Prüss, Carsten Finke

Source: J Neurol
Journal of neurology 271(9), 5886-5898 (2024). doi:10.1007/s00415-024-12545-4

Subject Terms: Male, Adult, Memory, Long-Term, Adolescent, Original Communication, Anti, Diffusion-weighted MRI, Graph analysis, Human connectome, pathology [Nerve Net], physiopathology [Default Mode Network], diagnostic imaging [Memory Disorders], Hippocampus, physiology [Memory, Long-Term], Young Adult, physiopathology [Nerve Net], Connectome, physiopathology [Memory Disorders], Humans, pathology [Memory Disorders], ddc:610, physiopathology [Anti-N-Methyl-D-Aspartate Receptor Encephalitis], diagnostic imaging [Hippocampus], Anti-N-Methyl-D-Aspartate Receptor Encephalitis, pathology [Default Mode Network], Memory Disorders, diagnostic imaging [Nerve Net], complications [Anti-N-Methyl-D-Aspartate Receptor Encephalitis], Default Mode Network, pathology [Anti-N-Methyl-D-Aspartate Receptor Encephalitis], Middle Aged, ddc, etiology [Memory Disorders], 3. Good health, diagnostic imaging [Anti-N-Methyl-D-Aspartate Receptor Encephalitis], pathology [Hippocampus], Diffusion Tensor Imaging, Anti-N-Methyl-d-Aspartate receptor encephalitis, Integrative Biomedicine [Topic 3], Female, Memory Disorders/pathology [MeSH], Nerve Net/physiopathology [MeSH], Anti-N-Methyl-D-Aspartate Receptor Encephalitis/physiopathology [MeSH], Male [MeSH], Nerve Net/diagnostic imaging [MeSH], Anti-N-Methyl-D-Aspartate Receptor Encephalitis/diagnostic imaging [MeSH], Memory Disorders/diagnostic imaging [MeSH], Anti-N-Methyl-D-Aspartate Receptor Encephalitis/complications [MeSH], Hippocampus/diagnostic imaging [MeSH], Adolescent [MeSH], Female [MeSH], Diffusion Tensor Imaging [MeSH], Adult [MeSH], Humans [MeSH], Connectome [MeSH], Anti-N-Methyl-D-Aspartate Receptor Encephalitis/pathology [MeSH], Memory Disorders/etiology [MeSH], Middle Aged [MeSH], Default Mode Network/physiopathology [MeSH], Memory, Long-Term/physiology [MeSH], Default Mode Network/diagnostic imaging [MeSH], Nerve Net/pathology [MeSH], Memory Disorders/physiopathology [MeSH], Young Adult [MeSH], Hippocampus/pathology [MeSH], Default Mode Network/pathology [MeSH], Nerve Net, Function and Dysfunction of the Nervous System, diagnostic imaging [Default Mode Network]

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Access URL: https://pubmed.ncbi.nlm.nih.gov/38977462
https://edoc.mdc-berlin.de/id/eprint/24519/2/24519suppl.docx
https://repository.publisso.de/resource/frl:6521189
https://mediatum.ub.tum.de/1770803