Melatonin Enhances the Mitochondrial Functionality of Brown Adipose Tissue in Obese-Diabetic Rats

Συγγραφείς: Agil, Ahmad, Navarro-Alarcon, Miguel, Ali, Fatma Abo Zakaib, Albrakati, Ashraf, Salagre, Diego, Campoy, Cristina, Elmahallawy, Ehab K.

Συνεισφορές: Agil,A, Salagre,D Department of Pharmacology and Neurosciences Institute, School of Medicine, University of Granada, Granada, Spain. Agil,A, Salagre,D, Campoy,C Biosanitary Research Institute of Granada (ibs.GRANADA), University Hospital of Granada, Granada, Spain. Navarro-Alarcon,M Department of Nutrition and Bromatology, School of Pharmacy, University of Granada, Granada, Spain. Ali,FAZ Department of Pathology and Clinical Pathology, Faculty of Veterinary Medicine, Sohag University, Sohag, Egypt. Albrakati,A Department of Human Anatomy, College of Medicine, Taif University,Taif, Saudi Arabia. Campoy,C Department of Pediatric, School of Medicine, University of Granada, Granada, Spain. Elmahallawy,EK Department of Zoonoses, Faculty of Veterinary Medicine, Sohag University, Sohag, Egypt., This work was supported by grant SAF2016-79794-R from the Ministerio de Ciencia e Innovación (Spain) and European Regional Development Fund (ERDF).

Θεματικοί όροι: Melatonin, Brown adipose tissue, Mitochondrial function, Zücker diabetic fatty rat, Melatonina, Tejido adiposo pardo, Roedores, Diabetes Mellitus Tipo 2, Medical Subject Headings::Organisms::Eukaryota::Animals, Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Rodentia::Muridae::Murinae::Rats, Medical Subject Headings::Anatomy::Tissues::Connective Tissue::Adipose Tissue::Adipose Tissue, Brown, Medical Subject Headings::Diseases::Nutritional and Metabolic Diseases::Metabolic Diseases::Glucose Metabolism Disorders::Diabetes Mellitus::Diabetes Mellitus, Type 2, Medical Subject Headings::Anatomy::Cells::Cellular Structures::Intracellular Space::Cytoplasm::Cytoplasmic Structures::Organelles::Mitochondria, Medical Subject Headings::Chemicals and Drugs::Carbohydrates::Monosaccharides::Hexoses::Glucose, Medical Subject Headings::Phenomena and Processes::Physiological Phenomena::Physiological Processes::Homeostasis, Medical Subject Headings::Phenomena and Processes::Cell Physiological Phenomena::Cell Physiological Processes::Cell Death::Apoptosis, Medical Subject Headings::Chemicals and Drugs::Heterocyclic Compounds::Heterocyclic Compounds, 2-Ring::Purines::Purine Nucleotides::Adenine Nucleotides::Adenosine Diphosphate, 2-Ring::Purines::Purine Nucleotides::Adenine Nucleotides::Adenosine Triphosphate

Περιγραφή αρχείου: application/pdf

Relation: https://www.mdpi.com/2076-3921/10/9/1482/htm; Agil A, Navarro-Alarcon M, Ali FAZ, Albrakati A, Salagre D, Campoy C, et al. Melatonin Enhances the Mitochondrial Functionality of Brown Adipose Tissue in Obese-Diabetic Rats. Antioxidants. 2021 Sep 17;10(9):1482; http://hdl.handle.net/10668/3727; PMC8466890

Διαθεσιμότητα: http://hdl.handle.net/10668/3727
https://doi.org/10.3390/antiox10091482

In Patients With Obesity, the Number of Adipose Tissue Mast Cells Is Significantly Lower in Subjects With Type 2 Diabetes

Συγγραφείς: David Lopez-Perez, Anaïs Redruello-Romero, Jesús Garcia-Rubio, Carlos Arana, Luis A. Garcia-Escudero, Francisco Tamayo, Jose D. Puentes-Pardo, Sara Moreno-SanJuan, Javier Salmeron, Armando Blanco, Julio Galvez, Josefa Leon, Ángel Carazo

Συνεισφορές: [Lopez-Perez,D, Puentes-Pardo,JD, Galvez,J] Department of Pharmacology, Faculty of Pharmacy, University of Granada, Granada, Spain. [Lopez-Perez,D, Redruello-Romero,A, Galvez,J, Leon,J, Carazo,A] Research Unit, Instituto de Investigación Biosanitaria de Granada (ibs.GRANADA), Granada, Spain. [Garcia-Rubio,J, Tamayo,F] Surgery Unit, San Cecilio University Hospital, Granada, Spain. [Arana,C] Endocrinology and Nutrition Unit, Virgen de las Nieves University Hospital, Granada, Spain. [García-Escuder,LA] Department of Statistics and Operative Research, Faculty of Sciences, University of Valladolid, Valladolid, Spain. [Moreno-SanJuan,S] Cytometry and Microscopy Research Service, Instituto de Investigación Biosanitaria de Granada (ibs.GRANADA), Granada, Spain. [Salmeron,J] Gastroenterology Unit, San Cecilio University Hospital, Granada, Spain. [Blanco,A] Department of Computer Science and Artificial Intelligence, University of Granada, Granada, Spain. [Galvez,J] Centro de Investigación Biomédica En Red para Enfermedades Hepáticas y Digestivas (CIBER-EHD), Center for Biomedical Research, University of Granada, Granada, Spain. [Leon,J, Carazo,A] Clinical Management Unit of Digestive Disease, San Cecilio University Hospital, Granada, Spain., Instituto de Salud Carlos III (grant PI18/01947). Instituto de Salud Carlos III is a research institution from the Spanish government that funds biomedical research. Instituto de Salud Carlos III funded all the experiments.

Πηγή: Front Immunol
Digibug. Repositorio Institucional de la Universidad de Granada
instname
Universidad de Granada (UGR)
Digibug: Repositorio Institucional de la Universidad de Granada
RISalud-ANDALUCIA. Repositorio Institucional de Salud de Andalucía
Frontiers in Immunology, Vol 12 (2021)

Θεματικοί όροι: 0301 basic medicine, obesity, Medical Subject Headings::Chemicals and Drugs::Biological Factors::Biological Markers, Medical Subject Headings::Anatomy::Digestive System::Gastrointestinal Tract::Intestines::Intestinal Mucosa, Adipose Tissue, White, Medical Subject Headings::Anatomy::Tissues::Connective Tissue::Adipose Tissue::Adipose Tissue, White, Medical Subject Headings::Diseases::Nutritional and Metabolic Diseases::Metabolic Diseases::Glucose Metabolism Disorders::Diabetes Mellitus::Diabetes Mellitus, Type 2, Immunology, Adipose tissue, Neovascularization, Physiologic, Cell Count, Medical Subject Headings::Diseases::Nutritional and Metabolic Diseases::Nutrition Disorders::Overnutrition::Obesity, Medical Subject Headings::Anatomy::Cells::Connective Tissue Cells::Mast Cells, Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans, Mast cell, Immunophenotyping, angiogenesis, 03 medical and health sciences, Humans, T2D, Flow cytometry, Mast Cells, Obesity, Medical Subject Headings::Anatomy::Tissues::Connective Tissue::Adipose Tissue, Intestinal Mucosa, 10. No inequality, Inflammation, 2. Zero hunger, 0303 health sciences, Adipogenesis, flow cytometry, Medical Subject Headings::Phenomena and Processes::Circulatory and Respiratory Physiological Phenomena::Cardiovascular Physiological Phenomena::Cardiovascular Physiological Processes::Neovascularization, Physiologic, Medical Subject Headings::Phenomena and Processes::Cell Physiological Phenomena::Cell Physiological Processes::Cell Differentiation::Adipogenesis, RC581-607, adipose tissue, 3. Good health, Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Diagnosis::Diagnostic Techniques and Procedures::Clinical Laboratory Techniques::Immunologic Tests::Immunophenotyping, Adipose Tissue, Diabetes Mellitus, Type 2, Angiogenesis, Immunologic diseases. Allergy, mast cell, Biomarkers

Περιγραφή αρχείου: application/pdf; application/vnd.openxmlformats-officedocument.wordprocessingml.document

Σύνδεσμος πρόσβασης: https://pubmed.ncbi.nlm.nih.gov/34093556
http://hdl.handle.net/10668/3523
https://doaj.org/article/8213980e590e43e2ba2c4b49b47d88f1
https://www.frontiersin.org/articles/10.3389/fimmu.2021.664576/full
https://digibug.ugr.es/handle/10481/69363
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8177010
https://www.ncbi.nlm.nih.gov/pubmed/34093556
https://pubmed.ncbi.nlm.nih.gov/34093556/
https://europepmc.org/articles/PMC8177010/figure/f3/
http://hdl.handle.net/10481/69363
https://hdl.handle.net/10668/3523

Oleic Acid Protects Against Insulin Resistance by Regulating the Genes Related to the PI3K Signaling Pathway

Συγγραφείς: López-Gómez, Carlos, Santiago-Fernández, Concepción, García-Serrano, Sara, García-Escobar, Eva, Gutiérrez-Repiso, Carolina, Rodríguez-Díaz, Cristina, Ho-Plágaro, Ailec, Martín-Reyes, Flores, Garrido-Sánchez, Lourdes, Valdés, Sergio, Rodríguez-Cañete, Alberto, Rodríguez-Pacheco, Francisca, García-Fuentes, Eduardo

Συνεισφορές: López-Gómez,C, Santiago-Fernández,C, Rodríguez-Díaz,C, Ho-Plágaro,A, Martín-Reyes,F, Rodríguez-Pacheco,F, García-Fuentes,E Unidad de Gestión Clínica de Aparato Digestivo, Hospital Universitario Virgen de la Victoria/Instituto de Investigación Biomédica de Málaga-IBIMA, Málaga, Spain. García-Serrano,S, García-Escobar,E, Valdés,S Unidad de Gestión Clínica de Endocrinología y Nutrición, Hospital Regional Universitario de Málaga/Instituto de Investigación Biomédica de Málaga-IBIMA, Málaga, Spain. García-Serrano,S, Valdés,S, Rodríguez-Pacheco,F CIBER de Diabetes y Enfermedades Metabólicas Asociadas-CIBERDEM, Málaga, Spain. Gutiérrez-Repiso,C, Garrido-Sánchez,L Unidad de Gestión Clínica de Endocrinología y Nutrición, Hospital Universitario Virgen de la Victoria/Instituto de Investigación Biomédica de Málaga-IBIMA, Málaga, Spain. Garrido-Sánchez,L CIBER Fisiopatología de la Obesidad y Nutrición-CIBEROBN, Málaga, Spain. Rodríguez-Cañete,A Unidad de Gestión Clínica de Cirugía General, Digestiva y Trasplantes, Hospital Regional Universitario de Málaga, Málaga, Spain., This work was supported in part by a grant from the Instituto de Salud Carlos III, Spain (PI09/01016), and from a grant of the Consejería de Economía, Innovación y Ciencia de la Junta de Andalucía, Spain (CTS8081). This study has been co-funded by FEDER funds (“A way to make Europe”) (“Andalucía se mueve con Europa”). CIBER Fisiopatología de la Obesidad y Nutrición (CIBEROBN) and CIBER de Diabetes y Enfermedades Metabólicas Asociadas (CIBERDEM) are ISCIII projects. all authors have read the journal’s authorship statement. CLG is supported by a grant from the Ministerio de Educación y Formación Professional (Spain) (IJCI-2017-31466). CSF is supported by a grant from the ISCIII (Spain) (FI16/00241). CGR is supported by a grant from the Ministerio de Educación y Formación Professional (Spain) (IJCI-2017-33065). CRD is supported by a grant from the ISCIII (Spain) (CD18/00188). AHP is supported by a grant from the Ministerio de Educación y Formación Professional (Spain) (FPU14/01972). FMR is supported by a grant from the ISCIII (Spain) (“PFIS” program, FI19/00189). LGS is supported by the Miguel Servet program from the ISCIII (Spain) (“Miguel Servet II” program, CPII18/00030) and Nicolas Monardes program from the Consejería de Salud de Andalucía (Spain) (C-0028-2018). FRP is supported by the Miguel Servet program from the ISCIII (Spain) (“Miguel Servet I” program, CP18/00042). EGF is supported by the Nicolas Monardes program from the Consejería de Salud de Andalucía (Spain) (C-0031-2016).

Θεματικοί όροι: Morbid obesity, Insulin resistance, IRS1, p85α, p110β, Palmitic acid, Oleic acid, Docosahexaenoic acid, Linoleic acid, Visceral adipose tissue, Obesidad mórbida, Resistencia a la insulina, Ácido palmítico, Ácido oléico, Ácidos docosahexaenoicos, Ácido linoleico, Grasa intraabdominal, Andalucía, Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans, Medical Subject Headings::Diseases::Nutritional and Metabolic Diseases::Metabolic Diseases::Glucose Metabolism Disorders::Hyperinsulinism::Insulin Resistance, Medical Subject Headings::Chemicals and Drugs::Enzymes and Coenzymes::Enzymes::Transferases::Phosphotransferases::Phosphotransferases (Alcohol Group Acceptor)::Phosphatidylinositol 3-Kinases, Medical Subject Headings::Anatomy::Tissues::Connective Tissue::Adipose Tissue::Adipose Tissue, White::Abdominal Fat::Intra-Abdominal Fat, Medical Subject Headings::Diseases::Nutritional and Metabolic Diseases::Nutrition Disorders::Overnutrition::Obesity::Obesity, Morbid, Medical Subject Headings::Anatomy::Cells::Connective Tissue Cells::Adipocytes, Medical Subject Headings::Phenomena and Processes::Cell Physiological Phenomena::Cell Physiological Processes::Signal Transduction, Medical Subject Headings::Phenomena and Processes::Genetic Phenomena::Genetic Processes::Gene Expression, Medical Subject Headings::Chemicals and Drugs::Lipids::Fatty Acids::Palmitic Acids, Medical Subject Headings::Chemicals and Drugs::Lipids::Phospholipids

Περιγραφή αρχείου: application/pdf

Relation: https://www.mdpi.com/2077-0383/9/8/2615/htm; López-Gómez C, Santiago-Fernández C, García-Serrano S, García-Escobar E, Gutiérrez-Repiso C, Rodríguez-Díaz C, et al. Oleic Acid Protects Against Insulin Resistance by Regulating the Genes Related to the PI3K Signaling Pathway. J Clin Med. 2020 Aug 12;9(8):2615; http://hdl.handle.net/10668/4103; PMC7463472

Διαθεσιμότητα: http://hdl.handle.net/10668/4103
https://doi.org/10.3390/jcm9082615

Adipose tissue glycogen accumulation is associated with obesity-linked inflammation in humans

Συγγραφείς: Anna M. Gómez-Foix, Francisco J. Tinahones, Xavier Duran, Pablo M. Garcia-Roves, Sonia Fernández-Veledo, Joan Vendrell, Alan R. Saltiel, Kelly Roche, Oscar Yanes, Marta Montori-Grau, Catalina Núñez-Roa, Lourdes Garrido-Sánchez, Victoria Ceperuelo-Mallafré, Carolina Serena, Prasanth Puthanveetil, Miriam Ejarque, Miguel Angel Rodríguez, Enrique Saez

Συνεισφορές: [Ceperuelo-Mallafré,V, Ejarque,M, Serena,C, Núñez-Roa,C, Roche,K, Vendrell,J, Fernández-Veledo,S] Hospital Universitari de Tarragona Joan XXIII, Institut d'Investigació Sanitària Pere Virgili, Universitat Rovira i Virgili, Tarragona, Spain. [Ceperuelo-Mallafré,V, Durán,X, Montori-Grau,M, Rodríguez,MA, Yánes,O, Gómez-Foix,AM, Fernández-Veledo,S] CIBER de Diabetes y Enfermedades Metabólicas Asociadas (CIBERDEM), Instituto de Salud Carlos III, Madrid, Spain. [Montori-Grau,M] Departament de Bioquímica i Biologia Molecular, Institut de Biomedicina de la Universitat de Barcelona (IBUB), Facultat de Biologia, Universitat de Barcelona, Barcelona, Spain. [Rodríguez,MA] Centre for Omic Sciences (COS), Institut d'Investigació Sanitària Pere Virgili, Universitat Rovira i Virgili, Tarragona, Spain. [Yanes,O] Department of Electronic Engineering, Universitat Rovira i Virgili, Tarragona, Spain. [Puthanveetil,P, Saltiel,AR] Life Sciences Institute, University of Michigan, Ann Arbor, MI, USA. [Garrido-Sánchez,L, Tinahones,FJ] Hospital Universitario Virgen de la Victoria, Instituto de Investigaciones Biomédicas de Málaga (IBIMA), Universidad de Málaga, IBIMA, Spain. [Garrido-Sánchez,L, Tinahones,FJ] CIBER de Fisiopatología de Obesidad y Nutrición (CIBEROBN), Instituto de Salud Carlos III, Madrid, Spain. [Sáez,E] Department of Chemical Physiology and The Skaggs Institute for Chemical Biology, The Scripps Research Institute, La Jolla, CA, USA. [García-Roves,PM] Departamento de Ciencias Fisiológicas II, Facultad de Medicina, Universitat de Barcelona, Barcelona, Spain., This study was supported by grants from the Spanish Ministry of Economy and Competitiveness (SAF2012-36186 to SF-V, PI14/00228 to JV and PI12/02355 to FJT). The Spanish Biomedical Research Center in Diabetes and Associated Metabolic Disorders (CIBERDEM) (CB07708/0012) is an initiative of the Instituto de Salud Carlos III. SF-V and LG-S acknowledge support from the 'Miguel Servet' tenure-track program (CP10/00438 and CP13/00188, respectively) from the Fondo de Investigación Sanitaria (FIS) co-financed by the European Regional Development Fund (ERDF).

Πηγή: Mol Metab
RISalud-ANDALUCIA. Repositorio Institucional de Salud de Andalucía
instname
Repisalud
Instituto de Salud Carlos III (ISCIII)
Articles publicats en revistes (Ciències Fisiològiques)
Dipòsit Digital de la UB
Universidad de Barcelona
Molecular Metabolism, Vol 5, Iss 1, Pp 5-18 (2016)
Molecular Metabolism, vol 5, iss 1

Θεματικοί όροι: Medical Subject Headings::Chemicals and Drugs::Carbohydrates::Monosaccharides::Hexoses::Glucose, 0301 basic medicine, Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Chemistry Techniques, Analytical::Mass Spectrometry, Macròfags, Physiology, Macrophage, Medical Subject Headings::Chemicals and Drugs::Enzymes and Coenzymes::Enzymes::Transferases::Glycosyltransferases::Hexosyltransferases::Glucosyltransferases::Glycogen Synthase, Obesidad, Medical Subject Headings::Phenomena and Processes::Cell Physiological Phenomena::Cell Physiological Processes::Cell Death::Autophagy, Índice de masa corporal, Grasa subcutánea, Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans, 2.1 Biological and endogenous factors, Glucógeno sintasa, Aetiology, Masculino, Internal medicine, 2. Zero hunger, 0303 health sciences, Adipocyte, Diabetes, Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Chemistry Techniques, Analytical::Spectrum Analysis::Magnetic Resonance Spectroscopy, Ratón, Biological Sciences, Humanos, 3. Good health, Medical Subject Headings::Check Tags::Male, Medical Subject Headings::Organisms::Eukaryota::Animals, Estrés fisiológico, Medical Subject Headings::Chemicals and Drugs::Enzymes and Coenzymes::Enzymes::Transferases::Phosphotransferases::Phosphotransferases (Alcohol Group Acceptor)::Protein Kinases::Protein-Serine-Threonine Kinases::TOR Serine-Threonine Kinases, Obesitat, Medical Subject Headings::Anatomy::Tissues::Connective Tissue::Adipose Tissue::Adipose Tissue, White::Subcutaneous Fat, Original Article, Resistència a la insulina, Glycogen, Resistencia a la insulina, Serina-Treonina Quinasas TOR, 03 medical and health sciences, Affordable and Clean Energy, Autofàgia, Medical Subject Headings::Anatomy::Cells::Connective Tissue Cells::Adipocytes, Adipocitos, Autophagy, Medical Subject Headings::Phenomena and Processes::Physiological Phenomena::Body Constitution::Body Weights and Measures::Body Mass Index, Obesity, Metabolic and endocrine, Nutrition, Espectrometría de Masas, Macrophages, Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Rodentia::Muridae::Murinae::Mice, Espectroscopía de Resonancia Magnética, Insulin resistance, RC31-1245, Glicogen, Medical Subject Headings::Diseases::Nutritional and Metabolic Diseases::Metabolic Diseases::Glucose Metabolism Disorders::Hyperinsulinism::Insulin Resistance, Biochemistry and cell biology, Animales, Glucosa, Biochemistry and Cell Biology, Medical Subject Headings::Phenomena and Processes::Physiological Phenomena::Physiological Processes::Stress, Physiological

Περιγραφή αρχείου: application/pdf; application/vnd.openxmlformats-officedocument.wordprocessingml.document

Σύνδεσμος πρόσβασης: https://pubmed.ncbi.nlm.nih.gov/26844203
http://hdl.handle.net/10668/2220
http://hdl.handle.net/20.500.12105/17101
https://hdl.handle.net/2445/179528
http://hdl.handle.net/2445/179528
https://doaj.org/article/fd5e2d64a54b4718a269b27ec17db6d1
https://www.sciencedirect.com/science/article/pii/S2212877815001969
http://diposit.ub.edu/dspace/handle/2445/179528
https://www.ncbi.nlm.nih.gov/pubmed/26844203
https://escholarship.org/uc/item/7st9k7v3
https://pubmed.ncbi.nlm.nih.gov/26844203/
https://core.ac.uk/display/44128864
https://hdl.handle.net/10668/26322
https://hdl.handle.net/20.500.12105/17101
https://escholarship.org/content/qt7st9k7v3/qt7st9k7v3.pdf
https://escholarship.org/uc/item/7st9k7v3

DecreasedSTAMP2Expression in Association with Visceral Adipose Tissue Dysfunction

Συγγραφείς: Moreno-Navarrete, José María, Ortega, Francisco, Serrano, Marta, Pérez-Pérez, Rafael, Sabater, Mònica, Ricart, Wifredo, Tinahones Madueño, Francisco José, Peral, Belén, Fernández-Real, José Manuel

Συνεισφορές: [Moreno-Navarrete,JM, Ortega,F, Serrano,M, Sabater,M, Ricart,W, Fernández-Real,JM] Service of Diabetes, Endocrinology, and Nutrition, Institut d'Investigació Biomèdica de Girona, CIBEROBN and Instituto de Salud Carlos III, Girona, Spain. [Pérez-Pérez,R, Peral,B] Instituto de Investigaciones Biomédicas 'Alberto Sols' (IIB), Consejo Superior de Investigaciones Científicas and Universidad Autónoma de Madrid, Madrid, Spain. [Tinahones Madueño,FJ] Department of Endocrinology and Nutrition, Hospital Universitario Virgen de la Victoria de Málaga, CIBEROBN Fisiopatología Obesidad y Nutrición, Instituto de Salud Carlos III, Málaga, Spain., This work was supported by SAF-2009-10461 and Grant SAF-2008-02073 from the Ministerio de Ciencia e Innovación, Spain, and from the Fundación Mutua Madrileña, Spain.

Πηγή: RISalud-ANDALUCIA. Repositorio Institucional de Salud de Andalucía
instname
Digital.CSIC. Repositorio Institucional del CSIC
Consejo Superior de Investigaciones Científicas (CSIC)

Θεματικοί όροι: Medical Subject Headings::Anatomy::Tissues::Connective Tissue::Adipose Tissue::Adipose Tissue, White::Abdominal Fat::Intra-Abdominal Fat, Medical Subject Headings::Chemicals and Drugs::Organic Chemicals::Sulfur Compounds::Thiazoles::Thiazolidinediones, Adult, Male, 0301 basic medicine, Medical Subject Headings::Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Proteins::Membrane Proteins, Medical Subject Headings::Diseases::Nutritional and Metabolic Diseases::Metabolic Diseases::Glucose Metabolism Disorders::Diabetes Mellitus::Diabetes Mellitus, Type 2, Subcutaneous Fat, Gene Expression, Medical Subject Headings::Named Groups::Persons::Age Groups::Adult::Aged, Medical Subject Headings::Diseases::Nutritional and Metabolic Diseases::Nutrition Disorders::Overnutrition::Obesity, Intra-Abdominal Fat, Human obesity, STAMP2, Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans, Rosiglitazone, 03 medical and health sciences, Medical Subject Headings::Chemicals and Drugs::Chemical Actions and Uses::Pharmacologic Actions::Physiological Effects of Drugs::Hypoglycemic Agents, Medical Subject Headings::Anatomy::Cells::Connective Tissue Cells::Adipocytes, Medical Subject Headings::Named Groups::Persons::Age Groups::Adult, Adipocytes, Humans, Hypoglycemic Agents, Obesity, Medical Subject Headings::Named Groups::Persons::Age Groups::Adult::Middle Aged, Aged, 2. Zero hunger, 0303 health sciences, Tumor Necrosis Factor-alpha, Membrane Proteins, Type 2 diabetes, Medical Subject Headings::Check Tags::Female, Cell Differentiation, Medical Subject Headings::Phenomena and Processes::Cell Physiological Phenomena::Cell Physiological Processes::Cell Differentiation, Middle Aged, Medical Subject Headings::Chemicals and Drugs::Enzymes and Coenzymes::Enzymes::Oxidoreductases, Medical Subject Headings::Check Tags::Male, Diabetes Mellitus, Type 2, Medical Subject Headings::Anatomy::Tissues::Connective Tissue::Adipose Tissue::Adipose Tissue, White::Subcutaneous Fat, Medical Subject Headings::Phenomena and Processes::Genetic Phenomena::Genetic Processes::Gene Expression, Medical Subject Headings::Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Peptides::Intercellular Signaling Peptides and Proteins::Tumor Necrosis Factors::Tumor Necrosis Factor-alpha, Female, Thiazolidinediones, Gene expression, Oxidoreductases

Περιγραφή αρχείου: application/pdf

Σύνδεσμος πρόσβασης: https://academic.oup.com/jcem/article-pdf/96/11/E1816/9085338/jcem1816.pdf
https://pubmed.ncbi.nlm.nih.gov/21849520
http://hdl.handle.net/10668/705
http://hdl.handle.net/10261/40602
https://www.repositoriosalud.es/bitstream/10668/705/1/Moreno_Decreased.pdf
https://academic.oup.com/jcem/article/96/11/E1816/2833861
http://digital.csic.es/handle/10261/40602
https://core.ac.uk/display/36050656
https://www.repositoriosalud.es/handle/10668/705
https://europepmc.org/article/MED/21849520
https://hdl.handle.net/10668/705

Association between serum 25-hydroxyvitamin D and global DNA methylation in visceral adipose tissue from colorectal cancer patients

Συγγραφείς: Daniel Castellano-Castillo, Sonsoles Morcillo, Ana B. Crujeiras, Lidia Sánchez-Alcoholado, Mercedes Clemente-Postigo, Esperanza Torres, Francisco José Tinahones, Manuel Macias-Gonzalez

Συνεισφορές: [Castellano-Castillo,D, Morcillo,S, Sánchez-Alcoholado,L, Clemente-Postigo,M, Tinahones,FJ, Macias-Gonzalez,M] Unidad de Gestión Clínica Endocrinología y Nutrición. Instituto de Investigación Biomédica de Málaga (IBIMA), Complejo Hospitalario de Málaga (Virgen de la Victoria) Málaga (Spain). CIBER Fisiopatología de la Obesidad y Nutrición (CB06/03), Málaga, Spain. [Crujeiras,AB] Epigenomics in Endocrinology and Nutrition Group. Instituto de Investigacion Sanitaria (IDIS), Complejo Hospitalario Universitario de Santiago (CHUS) and CIBER Fisiopatologia de la Obesidad y Nutricion (CIBERobn), Málaga, Spain. [Torres,E] Unidad de Gestión Clínica de Oncología Intercentros Hospital Universitario Virgen de la Victoria, Málaga, Spain., This study was supported by 'Centros de Investigación En Red' (CIBER, CB06/03/0018) of the 'Instituto de Salud Carlos III' (ISCIII), and grants from ISCIII (PI11/01661) and from Consejeria de Innovacion, Ciencia y Empresa de la Junta de Andalucia (PI11-CTS-8181). Co financed by the European Regional Development Fund (FEDER).

Πηγή: BMC Cancer
Repisalud
Instituto de Salud Carlos III (ISCIII)
RISalud-ANDALUCIA. Repositorio Institucional de Salud de Andalucía
instname
BMC Cancer, Vol 19, Iss 1, Pp 1-7 (2019)

Θεματικοί όροι: Medical Subject Headings::Anatomy::Tissues::Connective Tissue::Adipose Tissue::Adipose Tissue, White::Abdominal Fat::Intra-Abdominal Fat, Male, 0301 basic medicine, Medical Subject Headings::Diseases::Neoplasms::Neoplasms by Site::Digestive System Neoplasms::Gastrointestinal Neoplasms::Intestinal Neoplasms::Colorectal Neoplasms, Vitamina D, Obesidad, Enzyme-Linked Immunosorbent Assay, Medical Subject Headings::Diseases::Nutritional and Metabolic Diseases::Nutrition Disorders::Overnutrition::Obesity, Intra-Abdominal Fat, Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans, 03 medical and health sciences, Neoplasias colorrectales, Humans, Medical Subject Headings::Chemicals and Drugs::Polycyclic Compounds::Steroids::Secosteroids::Vitamin D, Obesity, Vitamin D, RC254-282, Medical Subject Headings::Phenomena and Processes::Genetic Phenomena::Genetic Structures::Genome::Genome Components::Interspersed Repetitive Sequences::Retroelements::Long Interspersed Nucleotide Elements, Aged, Global DNA methylation, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, Epigenetic, Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Genetic Techniques::Sequence Analysis::Sequence Analysis, DNA, Medical Subject Headings::Check Tags::Female, Sequence Analysis, DNA, DNA Methylation, Middle Aged, Medical Subject Headings::Phenomena and Processes::Genetic Phenomena::Genetic Processes::DNA Methylation, Colorectal cancer, 3. Good health, Medical Subject Headings::Check Tags::Male, Long Interspersed Nucleotide Elements, Medical Subject Headings::Persons::Persons::Age Groups::Adult::Aged, Epigenómica, Multivariate Analysis, Female, Enzyme-Linked Immunosorbent Assay|Aged, Colorectal Neoplasms, Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Molecular Probe Techniques::Immunoassay::Immunoenzyme Techniques::Enzyme-Linked Immunosorbent Assay, Epigénesis genética, Nucleotide Elements, Metilación de ADN, Research Article

Περιγραφή αρχείου: application/pdf

Σύνδεσμος πρόσβασης: https://pubmed.ncbi.nlm.nih.gov/30665376
http://hdl.handle.net/20.500.12105/17811
http://hdl.handle.net/10668/3182
https://doaj.org/article/99ba311d930d46e4937ffa4d1e359a99
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6341579/
https://link.springer.com/article/10.1186/s12885-018-5226-4/tables/2
https://pubmed.ncbi.nlm.nih.gov/30665376/
https://link.springer.com/content/pdf/10.1186/s12885-018-5226-4.pdf
http://europepmc.org/abstract/MED/30665376
https://www.repositoriosalud.es/bitstream/10668/3182/1/CastellanoCastillo_AssociationBetween.pdf
https://hdl.handle.net/10668/3182
https://hdl.handle.net/20.500.12105/17811

RPL13A and EEF1A1 Are Suitable Reference Genes for qPCR during Adipocyte Differentiation of Vascular Stromal Cells from Patients with Different BMI and HOMA-IR.

Συγγραφείς: Gentile, Adriana-Mariel, Lhamyani, Said, Coín-Aragüez, Leticia, Oliva-Olivera, Wilfredo, Zayed, Hatem, Vega-Rioja, Antonio, Monteseirin, Javier, Romero-Zerbo, Silvana-Yanina, Tinahones, Francisco-José, Bermúdez-Silva, Francisco-Javier, El Bekay, Rajaa

Συνεισφορές: Gentile,AM, Lhamyani,S IBIMA, Universidad de Málaga, Málaga, España. Coín-Aragüez,L, Oliva-Olivera,W, Tinahones,FJ, El Bekay,R CIBER Pathophysiology of obesity and nutrition CB06/03, Carlos III Health Institute, Malaga, Spain, Laboratory of Biomedical Research, Virgen de la Victoria Clinical University Hospital, Málaga, Spain. Zayed,H Biomedical Sciences Program, Health Sciences Department, College of Arts and Sciences, Qatar University, Doha, Qatar. Vega-Rioja,A, Monteseirin,J Unidad de Gestión Clínica de Alergia Intercentros, Hospital Universitario Virgen Macarena, Sevilla, Spain. Romero-Zerbo,SY, Bermudez-Silva,FJ Unidad de Gestion Clínica Intercentros de Endocrinología y Nutrición, Instituto de Investigación Biomédica de Málaga (IBIMA), Hospital Regional Universitario de Málaga/Universidad de Málaga, Málaga, Spain. Centro de Investigación Biomédica en Red de Diabetes y Enfermedades Metabólicas Asociadas (CIBERDEM), Málaga, Spain. Tinahones,FJ Endocrinology Service, Virgen de la Victoria Clinical University Hospital, Malaga, Spain., This work was supported by grants from the Instituto de Salud Carlos III (PI10/01947, PI13/ 02628) with Fondos FEDER and the Consejería de Economía e Innovación, Ciencia y Empleo, Junta de Andalucía (CTS-7895). This work was supported by the FIS-Thematic Networks and Co-Operative Research Centres RIRAAF (RD07-0064).

Θεματικοί όροι: Adipocitos, Adipogénesis, Procesos biológicos, Índice de masa corporal, Expresión génica, Humanos, Resistencia a la insulina, Reacción en cadena de la polimerasa en tiempo real, Células del estroma, Grasa subcutánea, Medical Subject Headings::Anatomy::Cells::Connective Tissue Cells::Adipocytes, Medical Subject Headings::Phenomena and Processes::Cell Physiological Phenomena::Cell Physiological Processes::Cell Differentiation::Adipogenesis, Medical Subject Headings::Phenomena and Processes::Biological Phenomena::Biological Processes, Medical Subject Headings::Phenomena and Processes::Physiological Phenomena::Body Constitution::Body Weights and Measures::Body Mass Index, Medical Subject Headings::Phenomena and Processes::Genetic Phenomena::Genetic Processes::Gene Expression, Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans, Medical Subject Headings::Phenomena and Processes::Physiological Phenomena::Pharmacological Phenomena::Drug Resistance::Insulin Resistance, Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Genetic Techniques::Nucleic Acid Amplification Techniques::Polymerase Chain Reaction::Real-Time Polymerase Chain Reaction, Medical Subject Headings::Anatomy::Cells::Connective Tissue Cells::Stromal Cells, Medical Subject Headings::Anatomy::Tissues::Connective Tissue::Adipose Tissue::Adipose Tissue, White::Subcutaneous Fat

Περιγραφή αρχείου: application/pdf; application/vnd.openxmlformats-officedocument.wordprocessingml.document

Relation: http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0157002#abstract0; Gentile AM, Lhamyani S, Coín-Aragüez L, Oliva-Olivera W, Zayed H, Vega-Rioja A, et al. RPL13A and EEF1A1 Are Suitable Reference Genes for qPCR during Adipocyte Differentiation of Vascular Stromal Cells from Patients with Different BMI and HOMA-IR. PLoS ONE. 2016; 11(6):e0157002; http://hdl.handle.net/10668/2443; PMC4909211

Διαθεσιμότητα: http://hdl.handle.net/10668/2443
https://doi.org/10.1371/journal.pone.0157002

Adipose tissue fatty acid chain length and mono-unsaturation increases with obesity and insulin resistance.

Συγγραφείς: Yew Tan, Chong, Virtue, Samuel, Murfitt, Steven, Robert, Lee D, Phua, Yi Hui, Dale, Martin, Griffin, Julian L, Tinahones, Francisco, Scherer, Philipp E, Vidal-Puig, Antonio

Συνεισφορές: Yew Tan,C, Virtue,S, Dale,M, Vidal-Puig,A University of Cambridge Metabolic Research Laboratories, Institute of Metabolic Science, MDU MRC. Addenbrooke’s Hospital, Cambridge, UK. Murfitt,S, Robert,LD, Phua,YH, Griffin,JL University of Cambridge Department of Biochemistry, Cambridge, UK. Tinahones,FJ UGC Endocrinologia y Nutrición (IBIMA), Hospital Virgen de la Victoria. CIBER of Physiopathology, Obesity and Nutrition (CIBEROBN) Málaga, Spain. Scherer,P Touchstone Diabetes Center, Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, Texas, USA. Vidal-Puig,A Wellcome Trust Sanger Institute, Hinxton, Uk. Robert,LD, Griffin,JL Medical Research Council – Human Nutrition Research, Elsie Widdowson Laboratory, Cambridge, Uk., BB/H002731/1, Biotechnology and Biological Sciences Research Council, United Kingdom, BB/H013539/1, Biotechnology and Biological Sciences Research Council, United Kingdom, MC_G0802535, Medical Research Council, United Kingdom, MC_PC_13030, Medical Research Council, United Kingdom, MC_UP_A090_1006, Medical Research Council, United Kingdom, MC_UU_12012/2, Medical Research Council, United Kingdom, RG/12/13/29853, British Heart Foundation, United Kingdom

Θεματικοί όροι: Adiponectina, Tejido adiposo, Adiposidad, Ácidos grasos, esenciales, Ácidos grasos monoinsaturados, Humanos, Gato, Grasa intra-abdominal, Obesidad, Grasa subcutánea, Medical Subject Headings::Chemicals and Drugs::Hormones, Hormone Substitutes, and Hormone Antagonists::Hormones::Peptide Hormones::Adipokines::Adiponectin, Medical Subject Headings::Anatomy::Tissues::Connective Tissue::Adipose Tissue, Medical Subject Headings::Phenomena and Processes::Chemical Phenomena::Biochemical Phenomena::Body Composition::Body Fat Distribution::Adiposity, Medical Subject Headings::Chemicals and Drugs::Inorganic Chemicals::Elements::Carbon, Medical Subject Headings::Chemicals and Drugs::Lipids::Fatty Acids::Fatty Acids, Unsaturated::Fatty Acids, Essential, Monounsaturated, Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans, Medical Subject Headings::Phenomena and Processes::Physiological Phenomena::Pharmacological Phenomena::Drug Resistance::Insulin Resistance, Medical Subject Headings::Organisms::Eukaryota::Animals, Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Rodentia::Muridae::Murinae::Mice, Medical Subject Headings::Anatomy::Tissues::Connective Tissue::Adipose Tissue::Adipose Tissue, White::Abdominal Fat::Intra-Abdominal Fat, Medical Subject Headings::Diseases::Nutritional and Metabolic Diseases::Nutrition Disorders::Overnutrition::Obesity, Medical Subject Headings::Chemicals and Drugs::Lipids::Glycerides::Triglycerides

Περιγραφή αρχείου: application/pdf; application/msword

Relation: http://www.nature.com/articles/srep18366; Yew Tan C, Virtue S, Murfitt S, Robert LD, Phua YH, Dale M, et al. Adipose tissue fatty acid chain length and mono-unsaturation increases with obesity and insulin resistance. Sci Rep. 2015; 5:18366; http://hdl.handle.net/10668/2271; PMC4683622

Διαθεσιμότητα: http://hdl.handle.net/10668/2271
https://doi.org/10.1038/srep18366

Hypoxia is associated with a lower expression of genes involved in lipogenesis in visceral adipose tissue.

Συγγραφείς: García-Fuentes, Eduardo, Santiago-Fernández, Concepción, Gutiérrez-Repiso, Carolina, Mayas, María D, Oliva-Olivera, Wilfredo, Coín-Aragüez, Leticia, Alcaide, Juan, Ocaña-Wilhelmi, Luis, Vendrell, Joan, Tinahones, Francisco J, Garrido-Sánchez, Lourdes

Συνεισφορές: García-Fuentes,E, Gutiérrez-Repiso,C Department of Endocrinology and Nutrition, Institute of Biomedical Research of Malaga (IBIMA), Regional University Hospital, Malaga, Spain. García-Fuentes,E, Oliva-Olivera,W, Coín-Aragüez, L, Alcaide,J, Tinahones,FJ, Garrido-Sánchez,L CIBEROBN, Institute of Health Carlos III, Malaga, Spain. Santiago-Fernández,C, Coín-Aragüez,L, Garrido-Sánchez,L Department of Endocrinology and Nutrition, Institute of Biomedical Research of Malaga (IBIMA), Virgen de la Victoria Clinical University Hospital, Malaga, Spain. Mayas,MD Department of Physiology, University of Jaen, Jaén, Spain. Ocaña-Wilhelmi,L Department of Surgery, Institute of Biomedical Research of Malaga (IBIMA), Virgen de la Victoria Clinical University Hospital, Malaga, Spain. Vendrell,J CIBERDEM, Institute of Health Carlos III, Tarragona, Spain. Department of Endocrinology and Nutrition, Joan XXIII University Hospital, Pere Virgili Institute, Rovira i Virgili University, Tarragona, Spain. García-Fuentes,E Laboratorio de Investigación, Hospital Civil, Málaga, Spain., This work was supported in part by grants from Instituto de Salud Carlos III (PS09/01060, PS09/00997 and CP13/00188) and Consejería de Innovación, Ciencia y Empresa de la Junta de Andalucía (CTS-08081) (Spain). This study has been co-funded by FEDER funds.

Θεματικοί όροι: Adipogénesis, Tejido adiposo, Índice de masa corporal, Dieta, Ayuno, Factor 1 inducible por hipoxia, Resistencia a la insulina, Grasa intraabdominal, Lipogénesis, Ratones, Humanos, Obesidad mórbida, PPAR gamma, ARN mensajero, Proteína 1 de unión a elementos reguladores de esteroles, Medical Subject Headings::Phenomena and Processes::Cell Physiological Phenomena::Cell Physiological Processes::Cell Differentiation::Adipogenesis, Medical Subject Headings::Anatomy::Tissues::Connective Tissue::Adipose Tissue, Medical Subject Headings::Phenomena and Processes::Physiological Phenomena::Body Constitution::Body Weights and Measures::Body Mass Index, Medical Subject Headings::Phenomena and Processes::Physiological Phenomena::Nutritional Physiological Phenomena::Diet, Medical Subject Headings::Phenomena and Processes::Physiological Phenomena::Nutritional Physiological Phenomena::Diet::Fasting, Medical Subject Headings::Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Proteins::DNA-Binding Proteins::Basic Helix-Loop-Helix Transcription Factors::Hypoxia-Inducible Factor 1::Hypoxia-Inducible Factor 1, alpha Subunit, Medical Subject Headings::Phenomena and Processes::Physiological Phenomena::Pharmacological Phenomena::Drug Resistance::Insulin Resistance, Medical Subject Headings::Anatomy::Tissues::Connective Tissue::Adipose Tissue::Adipose Tissue, White::Abdominal Fat::Intra-Abdominal Fat, Medical Subject Headings::Phenomena and Processes::Metabolic Phenomena::Metabolism::Lipid Metabolism::Lipogenesis, Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Rodentia::Muridae::Murinae::Mice, Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans

Περιγραφή αρχείου: application/pdf

Relation: http://translational-medicine.biomedcentral.com/articles/10.1186/s12967-015-0732-5#Abs1; García-Fuentes E, Santiago-Fernández C, Gutiérrez-Repiso C, Mayas MD, Oliva-Olivera W, Coín-Aragüez L, et al. Hypoxia is associated with a lower expression of genes involved in lipogenesis in visceral adipose tissue. J Transl Med. 2015; 13:373; http://hdl.handle.net/10668/2449; PMC4663723

Διαθεσιμότητα: http://hdl.handle.net/10668/2449
https://doi.org/10.1186/s12967-015-0732-5

De novo lipogenesis in adipose tissue is associated with course of morbid obesity after bariatric surgery.

Συγγραφείς: Garrido-Sánchez, Lourdes, Vendrell, Joan, Fernández-García, Diego, Ceperuelo-Mallafré, María Victoria, Chacón, Matilde R, Ocaña-Wilhelmi, Luis, Alcaide, Juan, Tinahones Madueño, Francisco José, García-Fuentes, Eduardo

Συνεισφορές: Garrido-Sánchez,L, Vendrell,J, Chacón,MR Hospital Universitari Joan XXIII, IISPV, Tarragona, Spain. Fernández-García,D, Ceperuelo-Mallafré,MV, Tinahones Madueño,FJ Servicio de Endocrinología y Nutrición, Hospital Universitario Virgen de la Victoria, Málaga, Spain. Ocaña-Wilhelmi,L Servicio de Cirugía, Hospital Universitario Virgen de la Victoria, Málaga, Spain. Alcaide,J, García-Fuentes,E Fundación IMABIS, Málaga, Spain., This work was supported in part by grants from the Instituto de Salud Carlos III (PS09/01060, PS09/00997, PI08/0733, CP06/00119, JCI-2009-04086 and JCI-2010-06395) and Servicio Andaluz de Salud (PI0255/2007).

Θεματικοί όροι: aminoglycoside N1-acetyltransferase, ACACB protein, human, Acetil CoA Carboxilasa, Acetiltransferasas, Tejido adiposo, Antropometría, Cirugía bariátrica, Grasa Intraabdominal, Lipogénesis, lipolisis, ARN Mensajero, Grasa subcutánea, ATP Citrato (pro-S)-Liasa, Medical Subject Headings::Chemicals and Drugs::Enzymes and Coenzymes::Enzymes::Ligases::Carbon-Carbon Ligases::Acetyl-CoA Carboxylase, Medical Subject Headings::Chemicals and Drugs::Enzymes and Coenzymes::Enzymes::Transferases::Acyltransferases::Acetyltransferases, Medical Subject Headings::Anatomy::Tissues::Connective Tissue::Adipose Tissue, Medical Subject Headings::Named Groups::Persons::Age Groups::Adult, Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Anthropometry, Diagnostic and Therapeutic Techniques and Equipment::Surgical Procedures, Operative::Bariatric Surgery, Medical Subject Headings::Check Tags::Female, Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans, Medical Subject Headings::Anatomy::Tissues::Connective Tissue::Adipose Tissue::Adipose Tissue, White::Abdominal Fat::Intra-Abdominal Fat, Medical Subject Headings::Phenomena and Processes::Chemical Phenomena::Biochemical Phenomena::Biochemical Processes::Lipogenesis, Medical Subject Headings::Phenomena and Processes::Chemical Phenomena::Biochemical Phenomena::Biochemical Processes::Lipolysis, Medical Subject Headings::Check Tags::Male, Medical Subject Headings::Named Groups::Persons::Age Groups::Adult::Middle Aged

Περιγραφή αρχείου: application/pdf

Relation: http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0031280; Garrido-Sánchez L, Vendrell J, Fernández-García D, Ceperuelo-Mallafré V, Chacón MR, Ocaña-Wilhelmi L, et al. De novo lipogenesis in adipose tissue is associated with course of morbid obesity after bariatric surgery. PLoS ONE; 7(2):e31280; http://hdl.handle.net/10668/658; PMC3285616

Διαθεσιμότητα: http://hdl.handle.net/10668/658
https://doi.org/10.1371/journal.pone.0031280

Progression from high insulin resistance to type 2 diabetes does not entail additional visceral adipose tissue inflammation.

Συγγραφείς: Barbarroja Puerto, Nuria, López-Pedrera, Chary, Garrido-Sánchez, Lourdes, Mayas Torres, María Dolores, Oliva-Olivera, Wilfredo, Bernal-López, María Rosa, El Bekay, Rajaa, Tinahones Madueño, Francisco José

Συνεισφορές: Barbarroja Puerto,N, Oliva-Olivera,W, Bernal-López,MR, El Bekay,R, Tinahones Madueño,FJ Servicio de Endocrinología y Nutrición, Hospital Universitario Virgen de la Victoria, Málaga, Spain. Barbarroja Puerto,N, Tinahones Madueño,FJ Fundación IMABIS, Málaga, Spain. Barbarroja Puerto,N, Tinahones Madueño,FJ CIBER Fisiopatología de la Obesidad y Nutrición CB06/03, Instituto de Salud Carlos III, Madrid, Spain. López-Pedrera,C Unidad de Investigación, Hospital Reina Sofía-IMIBIC, Córdoba, Spain Garrido-Sánchez,L CIBERDEM, Hospital Universitari de Tarragona Joan XXIII, IISPV, Universitat Rovira i Virgili, Tarragona, Spain. Mayas Torres,MD Área de Fisiología, Universidad de Jaén, Spain., This work was supported by the Junta de Andalucia, (grant number P08-CTS-04369) and the Fondo de Investigación Sanitaria (grant number PS09/00997), Spain. NB was supported by a ‘‘Sara Borrell’’ postdoctoral contract from the ‘‘Instituto de Salud Carlos III’’, Spain. LGS was supported by a ‘‘Juan de la Cierva (JCI-2009-04086)’’ postdoctoral contrac.The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.

Θεματικοί όροι: Inflamación, Resistencia a la Insulina, Obesidad Mórbida, Diabetes Mellitus Tipo 2, Grasa Intraabdominal, FN-kappa B, Interleucina-1beta, Interleucina-6, Lípidos, ARN Mensajero, Proteína Quinasa 1 Activada por Mitógenos, Quinasa Activada por Mitógeno 3, Quinasas MAP Reguladas por Señal Extracelular, Factor de Transcripción STAT3, Factor de Necrosis Tumoral alfa, Humanos, Medical Subject Headings::Diseases::Pathological Conditions, Signs and Symptoms::Pathologic Processes::Inflammation, Medical Subject Headings::Diseases::Nutritional and Metabolic Diseases::Metabolic Diseases::Glucose Metabolism Disorders::Hyperinsulinism::Insulin Resistance, Medical Subject Headings::Diseases::Nutritional and Metabolic Diseases::Nutrition Disorders::Overnutrition::Obesity::Obesity, Morbid, Medical Subject Headings::Diseases::Nutritional and Metabolic Diseases::Metabolic Diseases::Glucose Metabolism Disorders::Diabetes Mellitus::Diabetes Mellitus, Type 2, Medical Subject Headings::Anatomy::Tissues::Connective Tissue::Adipose Tissue::Adipose Tissue, White::Abdominal Fat::Intra-Abdominal Fat, Medical Subject Headings::Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Proteins::DNA-Binding Proteins::NF-kappa B, and Proteins::Peptides::Intercellular Signaling Peptides and Proteins::Cytokines::Interleukins::Interleukin-1::Interleukin-1beta, and Proteins::Peptides::Intercellular Signaling Peptides and Proteins::Cytokines::Interleukins::Interleukin-6

Περιγραφή αρχείου: application/pdf

Relation: http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0048155; Barbarroja Puerto N, López-Pedrera C, Garrido-Sánchez L, Mayas Torres MD, Oliva-Olivera W, Bernal-López MR, et al. Progression from high insulin resistance to type 2 diabetes does not entail additional visceral adipose tissue inflammation. PLoS ONE. 2012; 7(10):e48155; http://hdl.handle.net/10668/768; PMC3480488

Διαθεσιμότητα: http://hdl.handle.net/10668/768
https://doi.org/10.1371/journal.pone.0048155

Zinc-alpha 2-glycoprotein gene expression in adipose tissue is related with insulin resistance and lipolytic genes in morbidly obese patients.

Συγγραφείς: Garrido-Sánchez, Lourdes, García-Fuentes, Eduardo, Fernández-García, Diego, Escoté, Xavier, Alcaide, Juan, Pérez-Martínez, Pablo, Vendrell, Joan, Tinahones, Francisco J

Συνεισφορές: Garrido-Sánchez,L, Escoté,X, Vendrell,J CIBERDEM, Hospital Universitari Joan XXIII, Pere Virgili Institute, Tarragona, Spain. García-Fuentes,E, AlcaideJ Fundación IMABIS, Málaga, Spain. García-Fuentes,E, Fernández-García,D, Pérez-Martínez,P Ciber Fisiopatología Obesidad y Nutrición (CIBEROBN), Málaga, Spain. Alcaide,J, Tinahones,FJ Servicio de Endocrinología y Nutrición, Hospital Universitario Virgen de la Victoria, Málaga, Spain. Pérez-Martínez,P Servicio de Medicina Interna, Hospital Universitario Reina Sofía, Córdoba, Spain., This work was supported in part by grants from the Programa Juan de la Cierva (JCI-2009-04086), Instituto de Salud Carlos III (CP04/00133, PS09/01060, PS09/00997), Servicio Andaluz de Salud (PI0255/2007).

Θεματικοί όροι: IRS1 protein, human, Zn-alpha-2-glycoprotein, marneral synthase, Arabidopsis, Proteínas de Arabidopsis, Regulación de la Expresión Génica, Proteínas Sustrato del Receptor de Insulina, Resistencia a la Insulina, Grasa Intraabdominal, Transferasas Intramoleculares, Lipólisis, Obesidad Mórbida, Proteínas de Plasma Seminal, Grasa Subcutánea, Medical Subject Headings::Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Proteins::Plant Proteins::Arabidopsis Proteins, Medical Subject Headings::Phenomena and Processes::Genetic Phenomena::Genetic Processes::Gene Expression Regulation, Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans, and Proteins::Peptides::Intracellular Signaling Peptides and Proteins::Adaptor Proteins, Signal Transducing::Insulin Receptor Substrate Proteins, Medical Subject Headings::Diseases::Nutritional and Metabolic Diseases::Metabolic Diseases::Glucose Metabolism Disorders::Hyperinsulinism::Insulin Resistance, Medical Subject Headings::Anatomy::Tissues::Connective Tissue::Adipose Tissue::Adipose Tissue, White::Abdominal Fat::Intra-Abdominal Fat, Medical Subject Headings::Chemicals and Drugs::Enzymes and Coenzymes::Enzymes::Isomerases::Intramolecular Transferases, Medical Subject Headings::Phenomena and Processes::Chemical Phenomena::Biochemical Phenomena::Biochemical Processes::Lipolysis, Medical Subject Headings::Check Tags::Male, Medical Subject Headings::Named Groups::Persons::Age Groups::Adult::Middle Aged, Medical Subject Headings::Diseases::Nutritional and Metabolic Diseases::Nutrition Disorders::Overnutrition::Obesity::Obesity

Περιγραφή αρχείου: application/pdf

Relation: http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0033264; Garrido-Sánchez L, García-Fuentes E, Fernández-García D, Escoté X, Alcaide J, Pérez-Martínez P, et al. Zinc-alpha 2-glycoprotein gene expression in adipose tissue is related with insulin resistance and lipolytic genes in morbidly obese patients. PLoS ONE. 2012; 7(3):e33264; http://hdl.handle.net/10668/1158; PMC3307730

Διαθεσιμότητα: http://hdl.handle.net/10668/1158
https://doi.org/10.1371/journal.pone.0033264

Adipose tissue gene expression of factors related to lipid processing in obesity.

Συγγραφείς: Clemente-Postigo, Mercedes, Queipo-Ortuño, María Isabel, Fernández-García, Diego José, Gómez-Huelgas, Ricardo, Tinahones Madueño, Francisco José, Cardona Díaz, Fernando

Συνεισφορές: Clemente-Postigo,M, Queipo-Ortuño,MI, Fernández-García,DJ Laboratorio de Investigaciones Biomédicas del Hospital Universitario Virgen de la Victoria, Málaga (Fundación IMABIS), Spain. Queipo-Ortuño,MI, Fernández-García,DJ, Gomez-Huelgas,R, Tinahones FJ, Cardona,F CIBER Fisiopatología de la Obesidad y la Nutrición, Spain. Fernández-García,DJ, Tinahones Madueño,FJ Servicio Endocrinología y Nutrición del Hospital Universitario Virgen de la Victoria, Málaga, Spain. Gómez-Huelgas,R Servicio de Medicina Interna del Hospital Regional Carlos Haya, Spain., This research group belongs to the ‘‘Centros de Investigación en Red’’ CIBER, CB06/03/0018 of the ‘‘Instituto de Salud Carlos III’’. This work was supported in part by a grant from the Instituto de Salud Carlos III CP07/0095, PI081655 and PS09/00997 Madrid, Spain, the Servicio Andaluz de Salud PI325/ 2008 , and author MCP is a recipient of a grant (FPU) from the Education Ministry, Madrid, Spain AP2009-4537 .

Θεματικοί όροι: LRP1 protein, human, acylation stimulating protein, Proteínas de Unión a Ácidos Grasos, Índice de masa corporal, Diabetes Mellitus Tipo 2, FABP4 protein, Expresión genética, Resistencia a la insulina, Péptidos y Proteínas de Señalización Intercelular, Grasa intraabdominal, Metabolismo de los Lípidos, Lipoproteína Lipasa, Proteina 1 Relacionada con Receptor de Lipoproteína de Baja Densidad, Obesidad mórbida, Reacción en Cadena de la Polimerasa de Transcriptasa Inversa, Grasa subcutánea, Medical Subject Headings::Phenomena and Processes::Physiological Phenomena::Body Constitution::Body Weights and Measures::Body Mass Index, Medical Subject Headings::Diseases::Nutritional and Metabolic Diseases::Metabolic Diseases::Glucose Metabolism Disorders::Diabetes Mellitus::Diabetes Mellitus, Type 2, Medical Subject Headings::Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Proteins::Carrier Proteins::Fatty Acid-Binding Proteins, Medical Subject Headings::Check Tags::Female, Medical Subject Headings::Phenomena and Processes::Genetic Phenomena::Genetic Processes::Gene Expression, Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans, Medical Subject Headings::Phenomena and Processes::Physiological Phenomena::Pharmacological Phenomena::Drug Resistance::Insulin Resistance, and Proteins::Peptides::Intercellular Signaling Peptides and Proteins, Medical Subject Headings::Anatomy::Tissues::Connective Tissue::Adipose Tissue::Adipose Tissue, White::Abdominal Fat::Intra-Abdominal Fat

Περιγραφή αρχείου: application/pdf

Relation: http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0024783; Clemente-Postigo M, Queipo-Ortuño MI, Fernandez-Garcia DJ, Gomez-Huelgas R, Tinahones Madueño FJ, Cardona Díaz F. Adipose tissue gene expression of factors related to lipid processing in obesity. PLoS ONE; 6(9):e24783; http://hdl.handle.net/10668/694; PMC3178563

Διαθεσιμότητα: http://hdl.handle.net/10668/694
https://doi.org/10.1371/journal.pone.0024783

Omics Approaches in Adipose Tissue and Skeletal Muscle Addressing the Role of Extracellular Matrix in Obesity and Metabolic Dysfunction

Συγγραφείς: Anguita-Ruiz, Augusto, Bustos-Aibar, Mireia, Plaza-Díaz, Julio, Mendez-Gutierrez, Andrea, Alcalá-Fdez, Jesús, Aguilera, Concepción María, Ruiz-Ojeda, Francisco Javier

Συνεισφορές: Anguita-Ruiz,A, Bustos-Aibar,M, Plaza-Díaz,J, Mendez-Gutierrez,A, Aguilera,CM, Ruiz-Ojeda,FJ Department of Biochemistry and Molecular Biology II, School of Pharmacy, University of Granada, Granada, Spain. Anguita-Ruiz,A, Ruiz-Ojeda,FJ Instituto de Investigación Biosanitaria IBS.GRANADA, Complejo Hospitalario Universitario de Granada, Granada, Spain. Anguita-Ruiz,A, Aguilera,CM Institute of Nutrition and Food Technology “José Mataix”, Center of Biomedical Research, University of Granada, Granada, Spain. Anguita-Ruiz,A, Aguilera,CM CIBEROBN (CIBER Physiopathology of Obesity and Nutrition), Instituto de Salud Carlos III, Madrid, Spain. Plaza-Díaz,J Children’s Hospital of Eastern Ontario Research Institute, Ottawa, Canada. Alcalá-Fdez,J Department of Computer Science and Artificial Intelligence, University of Granada, Granada, Spain. Ruiz-Ojeda,FJ RG Adipocytes and Metabolism, Institute for Diabetes and Obesity, Helmholtz Diabetes Center at Helmholtz Center Munich, Neuherberg, Munich, Germany., AMG is supported by a doctorate fellowship Formación del Profesorado Universitario (FPU 16/03653)”, which is being completed as part of the Nutrition and Food Sciences Program at the University of Granada, Spain. AAR is supported by a doctorate contract i-PFIS: Doctorados IIS-empresa en ciencias y tecnologías de la salud (IFI17/00048). JPD is supported by a grant to postdoctoral researchers at foreign Universities and Research Centers from the “Ramón-Areces Foundation”, Spain. FJRO is part of the “Personal Investigador Doctor”, University of Granada, funded by Junta de Andalucía (PAIDI, 2020).

Θεματικοί όροι: Obesity, Adipose tissue, Extracellular matrix, Skeletal muscle, Genetics, Epigenetic, Transcriptomic, Obesidad, Tejido adiposo, Matriz extracelular, Músculo esquelético, Genética, Epigenómica, Transcriptoma, Medical Subject Headings::Anatomy::Tissues::Connective Tissue::Adipose Tissue::Adipose Tissue, White, Medical Subject Headings::Organisms::Eukaryota::Animals, Medical Subject Headings::Anatomy::Cells::Cellular Structures::Extracellular Space::Extracellular Matrix, Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Genetic Techniques::Genetic Association Studies::Genome-Wide Association Study, Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans, Medical Subject Headings::Diseases::Nutritional and Metabolic Diseases::Metabolic Diseases, Medical Subject Headings::Anatomy::Musculoskeletal System::Muscles::Muscle, Skeletal, Medical Subject Headings::Diseases::Nutritional and Metabolic Diseases::Nutrition Disorders::Overnutrition::Obesity, Medical Subject Headings::Phenomena and Processes::Genetic Phenomena::Genetic Processes::Gene Expression Regulation::Epigenesis, Genetic, Medical Subject Headings::Phenomena and Processes::Chemical Phenomena::Biochemical Phenomena::Biochemical Processes::Transcription, Genetic::Transcriptome

Περιγραφή αρχείου: application/pdf

Relation: https://www.mdpi.com/1422-0067/22/5/2756/htm; Anguita-Ruiz A, Bustos-Aibar M, Plaza-Díaz J, Mendez-Gutierrez A, Alcalá-Fdez J, Aguilera CM, et al. Omics Approaches in Adipose Tissue and Skeletal Muscle Addressing the Role of Extracellular Matrix in Obesity and Metabolic Dysfunction. Int J Mol Sci. 2021 Mar 9;22(5):2756; http://hdl.handle.net/10668/4430; PMC7963192

Διαθεσιμότητα: http://hdl.handle.net/10668/4430
https://doi.org/10.3390/ijms22052756

Obesity-associated insulin resistance is correlated to adipose tissue vascular endothelial growth factors and metalloproteinase levels

Συγγραφείς: Tinahones, Francisco José, Coín-Aragüez, Leticia, Mayas, María Dolores, García-Fuentes, Eduardo, Hurtado-Del-Pozo, Carmen, Vendrell, Joan, Cardona, Fernando, Calvo, Rosa-María, Obregón, María-Jesus, El Bekay, Rajaa

Συνεισφορές: [Tinahones,FJ, Coín-Aragüez,L, Mayas,MD, García-Fuentes,E, Cardona,F, El Bekay,R] CIBER Fisiopatología Obesidad y Nutrición (CB06/03), Instituto de Salud Carlos III, Madrid, Spain. [Tinahones,FJ, El Bekay,R] Laboratorio de Investigación Biomédica, Hospital Universitario Virgen de la Victoria, Málaga, Spain. [Tinahones,FJ, Cardona,F] Servicio de Endocrinología, Hospital Universitario Virgen de la Victoria, Málaga, Spain. [Hurtado-Del-Pozo,C, Calvo,RM, Obregón,MJ] Instituto de Investigaciones Biomédicas (IIBM, CSIC-UAM]), Madrid, Spain. [Vendrell,J] CIBERDEM. University Hospital of Tarragona Joan XXIII. IISPV, Rovira i Virgili University, Tarragona, Spain., This work was supported in part by grants from the Andalusian Health Service [SAS PI-0251], from Fondos de Investigación Sanitaria PS09/00997, Instituto Carlos III, from Incentivos a Proyectos de Excelencia p08-CTS-04369. Consejería de Innovación, Junta de Andalucía, and Rajaa El Bekay is recipient of a post-doctoral grant 'Miguel Servet' (FIS-2007) (CP07/00288) from the Spanish Ministry of Health, and part of this project was supported by a grant from the Spanish Ministry of Health (FIS) (PI070953), and from Plan Nacional (MEC) SAF2009-09364 and S2010-BMD-2423 from Comunidad de Madrid. CIBEROBN is an initiative of ISCIII (Instituto de Salud Carlos III), Spain.

Πηγή: BMC Physiol
Digital.CSIC. Repositorio Institucional del CSIC
instname
Consejo Superior de Investigaciones Científicas (CSIC)
RISalud-ANDALUCIA. Repositorio Institucional de Salud de Andalucía

Θεματικοί όροι: Vascular Endothelial Growth Factor A, 0301 basic medicine, Medical Subject Headings::Chemicals and Drugs::Biological Factors::Biological Markers, Physiology, Medical Subject Headings::Anatomy::Body Regions::Torso::Abdomen::Abdominal Cavity::Peritoneum::Omentum, Medical Subject Headings::Phenomena and Processes::Physiological Phenomena::Pharmacological Phenomena::Drug Resistance::Insulin Resistance, Subcutaneous Fat, Medical Subject Headings::Diseases::Nutritional and Metabolic Diseases::Nutrition Disorders::Overnutrition::Obesity::Obesity, Morbid, Gene Expression, Neovascularization, Physiologic, Medical Subject Headings::Chemicals and Drugs::Enzymes and Coenzymes::Enzymes::Hydrolases::Peptide Hydrolases::Metalloproteases, Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans, Medical Subject Headings::Chemicals and Drugs::Biological Factors::Intercellular Signaling Peptides and Proteins::Angiogenic Proteins::Vascular Endothelial Growth Factors::Vascular Endothelial Growth Factor A, 03 medical and health sciences, Physiology (medical), Humans, Medical Subject Headings::Phenomena and Processes::Physiological Phenomena::Body Constitution::Body Weights and Measures::Body Size::Body Weight::Overweight::Obesity, Obesity, Medical Subject Headings::Anatomy::Tissues::Connective Tissue::Adipose Tissue, 2. Zero hunger, 0303 health sciences, Medical Subject Headings::Phenomena and Processes::Circulatory and Respiratory Physiological Phenomena::Cardiovascular Physiological Phenomena::Cardiovascular Physiological Processes::Neovascularization, Physiologic, Medical Subject Headings::Chemicals and Drugs::Chemical Actions and Uses::Pharmacologic Actions::Physiological Effects of Drugs::Growth Substances::Angiogenesis Modulating Agents::Angiogenesis Inducing Agents, Obesity, Morbid, 3. Good health, Adipose Tissue, Metalloproteases, Medical Subject Headings::Anatomy::Tissues::Connective Tissue::Adipose Tissue::Adipose Tissue, White::Subcutaneous Fat, Medical Subject Headings::Phenomena and Processes::Genetic Phenomena::Genetic Processes::Gene Expression, Angiogenesis Inducing Agents, Insulin Resistance, Omentum, Biomarkers, Research Article

Περιγραφή αρχείου: application/pdf

Σύνδεσμος πρόσβασης: https://bmcphysiol.biomedcentral.com/track/pdf/10.1186/1472-6793-12-4
https://pubmed.ncbi.nlm.nih.gov/22471305
http://hdl.handle.net/10261/52172
http://hdl.handle.net/10668/860
http://www.biomedcentral.com/content/pdf/1472-6793-12-4.pdf
http://digital.csic.es/handle/10261/52172
https://www.repositoriosalud.es/bitstream/10668/860/1/Tinahones_Obesity.pdf
https://link.springer.com/content/pdf/10.1186%2F1472-6793-12-4.pdf
https://bmcphysiol.biomedcentral.com/articles/10.1186/1472-6793-12-4/metrics
http://europepmc.org/articles/PMC3382430
https://hdl.handle.net/10668/860

Myocardial Ischemic Subject’s Thymus Fat: A Novel Source of Multipotent Stromal Cells

Συγγραφείς: Oliva-Olivera, Wilfredo, Coin-Araguez, Leticia, Salas, Julian, Lhamyani, Said, Gentile, Adriana-Mariel, Garcia, Esteban Sarria, Hmadcha, Abdelkrim, Zayed, Hatem, Vega-Rioja, Antonio, Tinahones, Francisco J., El Bekay, Rajaa

Συνεισφορές: [Oliva-Olivera,W, Coín-Aragüez,L, Tinahones,FJ, El Bekay,R] CIBER Pathophysiology of obesity and nutrition CB06/03, Carlos III Health Institute, Malaga, Spain, Laboratory of Biomedical Research, Virgen de la Victoria Clinical University Hospital, Málaga, Spain. [Salas,J, Sarria García,E] Cardiovascular Surgery Department, University Hospital Carlos Haya, Málaga, Spain. [Lhamyani,S, Gentile,AM] Research Laboratory, Science School, Málaga University, Málaga, Spain. [Hmadcha,A] Andalusian Center for Molecular Biology and Regenerative Medicine (CABIMER), Department of Stem Cells, Sevilla, Spain. Centro de Investigación Biomédica en Red-Diabetes y Enfermedades Metabólicas (CIBERDEM), Instituto de Salud Carlos III, Madrid, Spain. [Zayed,H] Biomedical Sciences Program, Health Sciences Department, College of Arts and Sciences, Qatar University, Doha, Qatar.[Vega-Rioja,A] Servicio Regional de Inmunología y Alergia, Hospital Universitario Virgen Macarena, Sevilla, Spain., Instituto de Salud Carlos III, European Commission, This work was supported in part by grants from the Instituto de Salud Carlos III/FEDER, EU (PI10/01947, PI13/02628), CTS-7895 from the Consejería de Economía e Innovación, Ciencia y Empleo, Junta de Andalucía/FEDER, EU. R. El Bekay is supported by fellowships from the ISCIII/ FEDER, EU 'Miguel Servet II' (CPII13/00041). AV-R is under a contract Proyectos de I+D+i para jóvenes investigadores from the Ministerio de Economía y Competitividad (SAF2014-60649-JIN) and co-funded by Fondo Europeo de Desarrollo Regional–FEDER.

Πηγή: PLoS One
Repisalud
Instituto de Salud Carlos III (ISCIII)
Digital.CSIC. Repositorio Institucional del CSIC
Consejo Superior de Investigaciones Científicas (CSIC)
RISalud-ANDALUCIA. Repositorio Institucional de Salud de Andalucía
instname
PLoS ONE, Vol 10, Iss 12, p e0144401 (2015)

Θεματικοί όροι: Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Cytological Techniques::Cell Separation::Flow Cytometry, 0301 basic medicine, Medical Subject Headings::Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Proteins::DNA-Binding Proteins::Basic-Leucine Zipper Transcription Factors::Basic Helix-Loop-Helix Leucine Zipper Transcription Factors::Sterol Regulatory Element Binding Proteins::Sterol Regulatory Element Binding Protein 1, adipose tissue stromal cell, subcutaneous fat, Myocardial Ischemia, Gene Expression, HLA DR antigen, Regenerative Medicine, Grasa subcutánea, Medicina regenerativa, Ensayo de unidades formadoras de colonias, thymus, Osteogenesis, adipose tissue cell, CD34 antigen, CD133 antigen, Diferenciación celular, Medical Subject Headings::Named Groups::Persons::Age Groups::Adult::Middle Aged, endoglin, 0303 health sciences, Adipogenesis, Mesenchymal Stromal Cells, Reverse Transcriptase Polymerase Chain Reaction, Medical Subject Headings::Phenomena and Processes::Cell Physiological Phenomena::Cell Physiological Processes::Cell Differentiation::Adipogenesis, Cell Differentiation, Middle Aged, Medical Subject Headings::Phenomena and Processes::Cell Physiological Phenomena::Cell Physiological Processes::Cell Growth Processes::Cell Proliferation, Flow Cytometry, adipose tissue, 3. Good health, stroma cell, Medical Subject Headings::Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Proteins::Carrier Proteins::Fatty Acid-Binding Proteins, Adipose Tissue, bone development, Medicine, Medical Subject Headings::Anatomy::Tissues::Connective Tissue::Adipose Tissue::Adipose Tissue, White::Subcutaneous Fat, Medical Subject Headings::Phenomena and Processes::Genetic Phenomena::Genetic Processes::Gene Expression, Isquemia miocárdica, Sterol Regulatory Element Binding Protein 1, Medical Subject Headings::Diseases::Cardiovascular Diseases::Heart Diseases::Myocardial Ischemia, Medical Subject Headings::Disciplines and Occupations::Health Occupations::Medicine::Regenerative Medicine, Research Article, Tejido adiposo, heart muscle ischemia, Science, Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Clinical Laboratory Techniques::Immunologic Tests::Immunophenotyping, colony forming unit F, osteocyte, Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Clinical Laboratory Techniques::Cytological Techniques::Colony-Forming Units Assay, Anciano, Subcutaneous Fat, thymus adipose tissue, Medical Subject Headings::Named Groups::Persons::Age Groups::Adult::Aged, Thymus Gland, adipocyte, Medical Subject Headings::Anatomy::Tissues::Lymphoid Tissue::Thymus Gland, Proteínas de unión a ácidos Ggrasos, Fatty Acid-Binding Proteins, adipogenesis, Immunophenotyping, Osteogénesis, Colony-Forming Units Assay, 03 medical and health sciences, Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Genetic Techniques::Nucleic Acid Amplification Techniques::Polymerase Chain Reaction::Reverse Transcriptase Polymerase Chain Reaction, Células del estroma mesenquimatoso, Proteína 1 de unión a los elementos reguladores de esteroles, Humans, Medical Subject Headings::Anatomy::Tissues::Connective Tissue::Adipose Tissue, Aged, Cell Proliferation, Mediana edad, Reacción en cadena de la polimerasa de transcriptasa inversa, CD19 antigen, Adipogénesis, Proliferación de la célula, CD45 antigen, Thy 1 antigen, cell adhesion, Mesenchymal Stem Cells, Medical Subject Headings::Phenomena and Processes::Cell Physiological Phenomena::Cell Physiological Processes::Cell Differentiation, CD14 antigen, cell differentiation, Inmunofenotipificación, Medical Subject Headings::Phenomena and Processes::Musculoskeletal and Neural Physiological Phenomena::Musculoskeletal Physiological Phenomena::Musculoskeletal Physiological Processes::Musculoskeletal Development::Bone Development::Osteogenesis, 5' nucleotidase, Timo, Medical Subject Headings::Anatomy::Cells::Connective Tissue Cells::Stromal Cells::Mesenchymal Stromal Cells, Citometría de flujo, cell structure, Expresión génica

Περιγραφή αρχείου: application/pdf; application/msword

Σύνδεσμος πρόσβασης: https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0144401&type=printable
https://pubmed.ncbi.nlm.nih.gov/26657132
http://hdl.handle.net/20.500.12105/17108
http://hdl.handle.net/10261/396434
https://api.elsevier.com/content/abstract/scopus_id/84957111429
http://hdl.handle.net/10668/2403
https://doaj.org/article/8bb7318bc9754f2d93b6d4a2e377dafd
https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0144401
https://core.ac.uk/display/76419929
https://www.ncbi.nlm.nih.gov/pubmed/26657132
https://pubmed.ncbi.nlm.nih.gov/26657132/
https://www.repositoriosalud.es/handle/10668/2403
https://paperity.org/p/74877583/myocardial-ischemic-subjects-thymus-fat-a-novel-source-of-multipotent-stromal-cells
https://hdl.handle.net/10576/4293
https://hdl.handle.net/20.500.12105/17108

CB1 Blockade Potentiates Down-Regulation of Lipogenic Gene Expression in Perirenal Adipose Tissue in High Carbohydrate Diet-Induced Obesity

Συγγραφείς: Vida, Margarita, Rivera, Patricia, Gavito, Ana Luisa, Suárez, Juan, Pavón, Francisco Javier, Arrabal, Sergio, Romero-Cuevas, Miguel, Bautista, Dolores, Martínez, Ana, Rodríguez de Fonseca, Fernando, Serrano, Antonia, Baixeras, Elena

Συνεισφορές: [Vida,M, Rivera,P, Gavito,AL, Suárez,J, Pavón,FJ, Arrabal,S, Romero-Cuevas,M, Rodriguez de Fonseca,F, Serrano.A] Unidad de Gestión Clínica de Salud Mental, Hospital Regional Universitario de Málaga, Universidad de Málaga, Málaga, Spain. [Baixeras,E] Unidad de Gestión Clínica de Medicina Interna, Hospital Regional Universitario de Málaga, Universidad de Málaga, Málaga, Spain. [Bautista,D] Unidad de Gestión Clínica de Anatomía Patológica, Hospital Regional Universitario de Málaga, Universidad de Málaga, Málaga, Spain. [Vida,M, Bautista,D, Rodríguez de Fonseca,F, Serrano,A, Baixeras,E] Instituto de Investigación Biomédica de Málaga (IBIMA), Hospital Regional Universitario de Málaga, Universidad de Málaga, Málaga, Spain. [Martínez,A] Instituto de Química Médica Lora Tamayo, Consejo Superior de Investigaciones Científicas. Madrid, Spain. [Vida,M, RiveraP, Rodríguez de Fonseca, Serrano,A] CIBER de Fisiopatología de la Obesidad y Nutrición (CIBEROBN), Santiago de Compostela, Spain., This work was supported by Grants: from the Spanish Institute of Health ‘‘Carlos III (PI061109, CP12/03109, CIBERobn EU-ERDF-CB06/03/1008), from the Andalusian Ministry of Health (PI0552), from Andalusian Ministry of Economy, Innovation, Science and Employment EU-ERDF (CTS-8221 and CTS-433), from Spanish Ministry of Science and Innovation (SAF2010-20521), from European Union’s 7th Framework Programme (Health- F2-2008-223713, REPROBESITY). I3SNS Program of the Spanish National Health System of Spanish Ministry of Science and Innovation.

Πηγή: PLoS One
Digital.CSIC. Repositorio Institucional del CSIC
instname
Consejo Superior de Investigaciones Científicas (CSIC)
RISalud-ANDALUCIA. Repositorio Institucional de Salud de Andalucía
PLoS ONE, Vol 9, Iss 2, p e90016 (2014)
PLoS ONE; Vol 9

Θεματικοί όροι: Male, 0301 basic medicine, Medical Subject Headings::Chemicals and Drugs::Heterocyclic Compounds::Heterocyclic Compounds, 1-Ring::Azoles::Pyrazoles, Time Factors, Medical Subject Headings::Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Proteins::Transcription Factors, Medical Subject Headings::Anatomy::Tissues::Connective Tissue::Adipose Tissue::Adipose Tissue, White, Obesidad, Riñón, Kidney, Piperidines, Receptor, Cannabinoid, CB1, Medical Subject Headings::Technology, Industry, Agriculture::Food and Beverages::Food::Dietary Carbohydrates, Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Rodentia::Muridae::Murinae::Rats::Rats, Wistar, 2. Zero hunger, Medical Subject Headings::Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Proteins::Membrane Proteins::Receptors, Cell Surface::Receptors, G-Protein-Coupled::Receptors, Cannabinoid::Receptor, Cannabinoid, CB1, 3. Good health, Medical Subject Headings::Check Tags::Male, Medical Subject Headings::Organisms::Eukaryota::Animals, Medicine, Medical Subject Headings::Phenomena and Processes::Cell Physiological Phenomena::Cell Physiological Processes::Signal Transduction, Research Article, Signal Transduction, Medical Subject Headings::Phenomena and Processes::Metabolic Phenomena::Metabolism::Lipid Metabolism::Lipogenesis, Science, Adipose Tissue, White, Tejido adiposo blanco, Down-Regulation, Diet, High-Fat, Alimentación rica en grasa, 03 medical and health sciences, Dietary Carbohydrates, Animals, Medical Subject Headings::Anatomy::Urogenital System::Urinary Tract::Kidney, Medical Subject Headings::Phenomena and Processes::Physiological Phenomena::Body Constitution::Body Weights and Measures::Body Size::Body Weight::Overweight::Obesity, Lipogénesis, Obesity, Rats, Wistar, Medical Subject Headings::Phenomena and Processes::Physiological Phenomena::Nutritional Physiological Phenomena::Diet::Diet, High-Fat, Lipogenesis, Body Weight, Medical Subject Headings::Phenomena and Processes::Physical Phenomena::Time::Time Factors, Peso corporal, Medical Subject Headings::Phenomena and Processes::Physiological Phenomena::Body Constitution::Body Weights and Measures::Body Size::Body Weight, Rats, Medical Subject Headings::Chemicals and Drugs::Heterocyclic Compounds::Heterocyclic Compounds, 1-Ring::Piperidines, Carbohidratos dietéticos, Medical Subject Headings::Phenomena and Processes::Physiological Phenomena::Physiological Processes::Pharmacological Processes::Down-Regulation, Pyrazoles, Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Rodentia::Muridae::Murinae::Rats, Transcription Factors

Περιγραφή αρχείου: application/pdf

Σύνδεσμος πρόσβασης: https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0090016&type=printable
https://pubmed.ncbi.nlm.nih.gov/24587189
http://hdl.handle.net/10261/101132
http://hdl.handle.net/10668/1976
https://doaj.org/article/3f25f651ec724cf09864ae78beeee2e6
http://digital.csic.es/bitstream/10261/101132/1/Plos%20one%202014.pdf
http://europepmc.org/articles/PMC3934980
https://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0090016
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3934980/
https://www.repositoriosalud.es/handle/10668/1976
https://digital.csic.es/handle/10261/101132
https://hdl.handle.net/10668/1976

FABP4 Dynamics in Obesity: Discrepancies in Adipose Tissue and Liver Expression Regarding Circulating Plasma Levels

Συγγραφείς: Francisco J. Tinahones, Xavier Escoté, Joan Vendrell, María Isabel Queipo-Ortuño, Fernando Cardona, Rafael Pérez-Pérez, Merce Miranda, Mercedes Clemente-Postigo, José Manuel Fernández-Real, Belén Peral, Lourdes Garrido-Sánchez, Victoria Ceperuelo-Mallafré

Συνεισφορές: [Queipo-Ortuño,MI, Ceperuelo-Mallafré,MV, Clemente-Postigo,M, Cardona Díaz,F] Laboratorio de Investigaciones Biomédicas del Hospital Universitario Virgen de la Victoria, Málaga, Spain. [Queipo-Ortuño,MI, Cardona Díaz,F] Fundación IMABIS, Málaga, Spain. [Queipo-Ortuño,MI, Pérez-Pérez,R, Peral,B, Cardona Díaz,F, Fernández-Real,JM, Tinahones Madueño,FJ] CIBER de Fisiopatología de la Obesidad y Nutrición (CIBEROBN), Instituto de Salud Carlos III, Madrid, Spain. [Escoté,X, Garrido-Sánchez,L, Miranda,M, Vendrell,J] Endocrinology and Diabetes Unit.Joan XXIII University Hospital, IISPV, Universitat Rovira i Virgili, Tarragona, Spain. [Escoté,X, Vendrell,J] CIBER de Diabetes y Enfermedades Metabólicas Asociadas (CIBERDEM), Instituto de Salud Carlos III, Madrid, Spain. [Pérez-Pérez,R, Peral,B] Instituto de Investigaciones Biomédicas, Alberto Sols, Consejo Superior de Investigaciones Científicas (CSIC) & Universidad Autónoma de Madrid (UAM), Madrid, Spain. [Fernández-Real,JM] Diabetes, Endocrinology and Nutrition Service, Institut d’Investigació Biomèdica de Girona (IdIBGi), Girona, Spain. [Tinahones Madueño,FJ] Servicio Endocrinología y Nutrición del Hospital Universitario Virgen de la Victoria, Málaga, Spain., This work was supported by Fondo de Investigacion Sanitaria (FIS) 07/1024, 08/1195, CB06/03/0018, CP07/0095 and PI081655, 10/00967, 11/00085 from the Spanish Instituto de Salud Carlos III (ISCIII), Ministerio de Sanidad y Consumo, with the participation of the European Regional Development Fund (ERDF) SAF-2009-10461 from the Ministerio de Economia y Competitividad (MICINN), the Servicio Andaluz de Salud (PI325/2008) and Fundación Mutua Madrileñaa, Spain (BP). LGS and VCM are supported by fellowships from the Juan de la Cierva programme (JdlC) (JCI200904086 and JCI-2010-06395). CIBERs are an ISCIII Project.

Πηγή: PLoS One
RIUMA. Repositorio Institucional de la Universidad de Málaga
Universidad de Málaga
Digital.CSIC. Repositorio Institucional del CSIC
instname
Repisalud
Instituto de Salud Carlos III (ISCIII)
RISalud-ANDALUCIA. Repositorio Institucional de Salud de Andalucía
PLoS ONE, Vol 7, Iss 11, p e48605 (2012)

Θεματικοί όροι: Índice de Masa Corporal, Male, 0301 basic medicine, FABP4, Peroxisome Proliferator-Activated Receptors, Obesidad, Medical Subject Headings::Diseases::Nutritional and Metabolic Diseases::Nutrition Disorders::Overnutrition::Obesity, Cell Separation, Resistencia a la Insulina, Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans, Body Mass Index, Cohort Studies, Mice, Subcutaneous Tissue, Medical Subject Headings::Health Care::Environment and Public Health::Public Health::Epidemiologic Measurements::Biometry::Anthropometry::Body Mass Index, Receptores Activados del Proliferador del Peroxisoma, Adipocytes, Tejido Adiposo, Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Genetic Techniques::Nucleic Acid Amplification Techniques::Polymerase Chain Reaction::Real-Time Polymerase Chain Reaction, 2. Zero hunger, 0303 health sciences, Hígado, Anthropometry, Middle Aged, Tejido Subcutáneo, Medical Subject Headings::Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Proteins::Carrier Proteins::Fatty Acid-Binding Proteins, Adipose Tissue, Liver, Medicine, Female, Research Article, Medical Subject Headings::Anatomy::Tissues::Connective Tissue::Adipose Tissue::Adipose Tissue, White::Abdominal Fat::Intra-Abdominal Fat, Animal Experimentation, Adult, Obesidad Mórbida, Science, Medical Subject Headings::Diseases::Nutritional and Metabolic Diseases::Nutrition Disorders::Overnutrition::Obesity::Obesity, Morbid, Adipose tissue, Medical Subject Headings::Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Proteins::DNA-Binding Proteins::Receptors, Cytoplasmic and Nuclear::Peroxisome Proliferator-Activated Receptors, Intra-Abdominal Fat, Real-Time Polymerase Chain Reaction, Fatty Acid-Binding Proteins, Medical Subject Headings::Anatomy::Digestive System::Liver, 03 medical and health sciences, ARN Mensajero, Medical Subject Headings::Phenomena and Processes::Chemical Phenomena::Biochemical Phenomena::Molecular Structure::Base Sequence, Animals, Humans, Obesity, RNA, Messenger, Medical Subject Headings::Anatomy::Tissues::Connective Tissue::Adipose Tissue, Plasma sanguíneo, Proteínas de Unión a Ácidos Grasos, Experimentación Animal, Medical Subject Headings::Anatomy::Tissues::Connective Tissue::Subcutaneous Tissue, Base Sequence, Medical Subject Headings::Chemicals and Drugs::Nucleic Acids, Nucleotides, and Nucleosides::Nucleic Acids::RNA::RNA, Messenger, Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Animal Experimentation, Reacción en Cadena en Tiempo Real de la Polimerasa, Medical Subject Headings::Diseases::Nutritional and Metabolic Diseases::Metabolic Diseases::Glucose Metabolism Disorders::Hyperinsulinism::Insulin Resistance, Mice, Inbred C57BL, Disease Models, Animal, Gene Expression Regulation, Insulin Resistance, Grasa Intraabdominal, Secuencia de Bases

Περιγραφή αρχείου: application/pdf

Σύνδεσμος πρόσβασης: https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0048605&type=printable
https://pubmed.ncbi.nlm.nih.gov/23139800
https://hdl.handle.net/10630/34102
http://hdl.handle.net/10261/76923
http://hdl.handle.net/20.500.12105/17042
http://hdl.handle.net/10668/845
https://doaj.org/article/2e3dc68d5895411d9b15fc98dab7db39
https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0048605
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3489666/
https://dx.plos.org/10.1371/journal.pone.0048605
https://pubmed.ncbi.nlm.nih.gov/23139800/
https://www.mendeley.com/catalogue/2635948f-254c-3f62-81dc-d286e4af3e74/
https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23139800/
https://hdl.handle.net/10668/845
https://hdl.handle.net/20.500.12105/17042