Analysis of Both Lipid Metabolism and Endocannabinoid Signaling Reveals a New Role for Hypothalamic Astrocytes in Maternal Caloric Restriction-Induced Perinatal Programming

Συγγραφείς: Tovar, Rubén, Vargas, Antonio, Aranda, Jesús, Sánchez-Salido, Lourdes, González-González, Laura, Chowen, Julie A., Rodríguez de Fonseca, Fernando, Suárez, Juan, Rivera, Patricia

Συνεισφορές: Tovar,R, Vargas,A, Aranda,J, Sánchez-Salido,L, González-González,L, Rodríguez de Fonseca,F, Suárez,J, Rivera,P Instituto de Investigación Biomédica de Málaga-IBIMA, Málaga, Spain. Tovar,R, Rivera,P UGC Salud Mental, Hospital Regional Universitario de Málaga, Málaga, Spain. Tovar,R, Aranda,J Andalucia Tech, Facultad de Medicina, Universidad de Málaga, Málaga, Spain. Chowen,JA Department of Endocrinology, Instituto de Investigación Biomédica la Princesa, Fundación Investigación Biomédica del Hospital Infantil Universitario Niño Jesús, Madrid, Spain. Chowen,JA CIBEROBN (Centro de Investigación Biomédica en Red Sobre Fisiopatología de la Obesidad y Nutrición), Instituto de Salud Carlos III, Madrid, Spain. Chowen,JA IMDEA Food Institute, CEI UAM + CSIC, Madrid, Spain. Suárez,J Departamento de Anatomía Humana, Medicina Legal e Historia de la Ciencia, Universidad de Málaga, Málaga, Spain., This research was funded by European Regional Development Funds-European Union (ERDF-EU) and Instituto de Salud Carlos III (ISCIII), grant numbers CP19/00068 and PI19/00343, Consejería de Economía, Conocimien to y Universidad, Junta de Andalucía, grant number P18-TP 5194. J.S. (CPII17/00024) holds a “Miguel Servet II” research contract from the National System of Health, EU-ERDF-ISCIII. P.R. (CP19/00068) holds a “Miguel Servet I” research contract from the National System of Health, ISCIII (CD19/00068), co-funded by ESF (“Investing in your future”).

Θεματικοί όροι: Perinatal programming, Hypothalamus, Astrocytes, Endocannabinoid system, Lipid metabolism, Atención perinatal, Hipotálamo, Astrocitos, Endocannabinoides, Metabolismo de los lípidos, Medical Subject Headings::Organisms::Eukaryota::Animals, Medical Subject Headings::Organisms::Eukaryota::Animals::Animal Population Groups::Animals, Newborn, Medical Subject Headings::Anatomy::Cells::Neuroglia::Astrocytes, Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Diagnosis::Diagnostic Techniques and Procedures::Physical Examination::Body Constitution::Body Weights and Measures::Body Size::Body Weight, Medical Subject Headings::Anatomy::Nervous System::Central Nervous System::Brain, Medical Subject Headings::Chemicals and Drugs::Lipids::Fatty Acids::Endocannabinoids, Medical Subject Headings::Check Tags::Female, Medical Subject Headings::Phenomena and Processes::Genetic Phenomena::Genetic Processes::Gene Expression Regulation, Medical Subject Headings::Diseases::Pathological Conditions, Signs and Symptoms::Pathologic Processes::Gliosis, Medical Subject Headings::Anatomy::Nervous System::Central Nervous System::Brain::Limbic System::Hypothalamus, Signs and Symptoms::Pathologic Processes::Inflammation, Medical Subject Headings::Phenomena and Processes::Reproductive and Urinary Physiological Phenomena::Reproductive Physiological Phenomena::Reproductive Physiological Processes::Reproduction::Pregnancy, Medical Subject Headings::Chemicals and Drugs::Nucleic Acids, Nucleotides, and Nucleosides::Nucleic Acids::RNA::RNA, Messenger, Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Rodentia::Muridae::Murinae::Rats

Περιγραφή αρχείου: application/pdf

Relation: https://www.mdpi.com/1422-0067/22/12/6292/htm; Tovar R, Vargas A, Aranda J, Sánchez-Salido L, González-González L, Chowen JA, et al. Analysis of Both Lipid Metabolism and Endocannabinoid Signaling Reveals a New Role for Hypothalamic Astrocytes in Maternal Caloric Restriction-Induced Perinatal Programming. Int J Mol Sci. 2021 Jun 11;22(12):6292; http://hdl.handle.net/10668/3956; PMC8230792

Διαθεσιμότητα: http://hdl.handle.net/10668/3956
https://doi.org/10.3390/ijms22126292

Aquaporin-4 Mediates Permanent Brain Alterations in a Mouse Model of Hypoxia-Aged Hydrocephalus

Συγγραφείς: Trillo-Contreras, José Luis, Toledo-Aral, Juan José, Villadiego, Javier, Echevarría, Miriam

Συνεισφορές: Trillo-Contreras,JL, Toledo-Aral,JJ, Villadiego,J, Echevarría,M Institute of Biomedicine of Seville-IBiS, University Hospital Virgen del Rocío, CSIC, University of Seville, Seville, Spain. Trillo-Contreras,JL, Echevarría,M Department of Medical Physiology and Biophysics, University of Seville, Seville, Spain. Toledo-Aral,JJ, Villadiego,J Network Center for Biomedical Research in Neurodegenerative Diseases (CIBERNED), Madrid, Spain, This study was supported by grants FIS: PI16/00493 and PI19/01096 from the Spanish Ministry of Economy and Competitiveness, co-financed by the Carlos III Health Institute (ISCIII) and European Regional Development Fund (FEDER).

Θεματικοί όροι: AQP4, Astrocytes, Hypoxia, Hydrocephalus, Cerebrospinal fluid, Cerebral ventricles, Homeostasis, Drainage, Acuaporina 4, Astrocitos, Hipoxia, Hidrocefalia, Líquido cefalorraquídeo, Ventrículos cerebrales, Drenaje, Medical Subject Headings::Health Care::Health Care Quality, Access, and Evaluation::Quality of Health Care::Epidemiologic Factors::Age Factors, Medical Subject Headings::Organisms::Eukaryota::Animals, Medical Subject Headings::Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Proteins::Carrier Proteins::Membrane Transport Proteins::Ion Channels::Porins::Aquaporins::Aquaporin 4, Medical Subject Headings::Chemicals and Drugs::Biological Factors::Biological Markers::Biomarkers, Pharmacological, Medical Subject Headings::Anatomy::Nervous System::Central Nervous System::Brain, Medical Subject Headings::Diseases::Animal Diseases::Disease Models, Animal, Medical Subject Headings::Diseases::Nervous System Diseases::Central Nervous System Diseases::Brain Diseases::Hydrocephalus, Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Diagnosis::Diagnostic Techniques and Procedures::Clinical Laboratory Techniques::Cytological Techniques::Histocytochemistry::Immunohistochemistry

Περιγραφή αρχείου: application/pdf

Relation: https://www.mdpi.com/1422-0067/22/18/9745/htm; Trillo-Contreras JL, Toledo-Aral JJ, Villadiego J, Echevarría M. Aquaporin-4 Mediates Permanent Brain Alterations in a Mouse Model of Hypoxia-Aged Hydrocephalus. Int J Mol Sci. 2021 Sep 9;22(18):9745; http://hdl.handle.net/10668/4403; PMC8471142

Διαθεσιμότητα: http://hdl.handle.net/10668/4403
https://doi.org/10.3390/ijms22189745

Impact of Visual Design Elements and Principles in Human Electroencephalogram Brain Activity Assessed with Spectral Methods and Convolutional Neural Networks

Συγγραφείς: Cabrera, Francisco E., Sánchez-Núñez, Pablo, Vaccaro, Gustavo, Peláez, José Ignacio, Escudero, Javier

Συνεισφορές: Cabrera,FE, Vaccaro,G, Peláez,JI Department of Languages and Computer Sciences, School of Computer Science and Engineering, Universidad de Málaga, Málaga, Spain. Cabrera,FE, Sánchez-Núñez,P, Peláez,JI Centre for Applied Social Research (CISA), Ada Byron Research Building, Universidad de Málaga, Málaga, Spain. Cabrera,FE, Peláez,JI Instituto de Investigación Biomédica de Málaga (IBIMA), Málaga, Spain. Sánchez-Núñez,P Department of Audiovisual Communication and Advertising, Faculty of Communication Sciences, Universidad de Málaga, Málaga, Spain. Escudero,J School of Engineering, Institute for Digital Communications (IDCOM), The University of Edinburgh, Edinburgh, UK., This research was partially supported by On the Move, an international mobility pro gramme organized by the Society of Spanish Researchers in the United Kingdom (SRUK) and CRUE Universidades Españolas. The Article Processing Charge (APC) was funded by the Programa Op erativo Fondo Europeo de Desarrollo Regional (FEDER) Andalucía 2014–2020 under Grant UMA 18-FEDERJA-148 and Plan Nacional de I+D+i del Ministerio de Ciencia e Innovación-Gobierno de España (2021-2024) under Grant PID2020-115673RB-100.

Θεματικοί όροι: EEG, Emotion classification, CNN, Spectral analysis, Visual perception, Visual attention, Visual features, Visual design elements and principles (VDEPs), Electroencefalografía, Emociones, Clasificación, Red nerviosa, Cariotipificación espectral, Percepción visual, Pruebas neuropsicológicas, Medical Subject Headings::Anatomy::Nervous System::Central Nervous System::Brain, Medical Subject Headings::Psychiatry and Psychology::Behavior and Behavior Mechanisms::Emotions, Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans, Medical Subject Headings::Phenomena and Processes::Mathematical Concepts::Neural Networks (Computer), Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Diagnosis::Diagnostic Techniques and Procedures::Diagnostic Techniques, Neurological::Electroencephalography, Medical Subject Headings::Humanities::Humanities::Music, Medical Subject Headings::Psychiatry and Psychology::Psychological Phenomena and Processes::Mental Processes::Perception::Visual Perception

Περιγραφή αρχείου: application/pdf

Relation: https://www.mdpi.com/1424-8220/21/14/4695; Cabrera FE, Sánchez-Núñez P, Vaccaro G, Peláez JI, Escudero J. Impact of Visual Design Elements and Principles in Human Electroencephalogram Brain Activity Assessed with Spectral Methods and Convolutional Neural Networks. Sensors. 2021 Jul 9;21(14):4695; http://hdl.handle.net/10668/4562; PMC8309592

Διαθεσιμότητα: http://hdl.handle.net/10668/4562
https://doi.org/10.3390/s21144695

Burden of rare variants in synaptic genes in patients with severe tinnitus: An exome based extreme phenotype study

Συγγραφείς: Amanat, Sana, Gallego-Martinez, Alvaro, Sollini, Joseph, Perez-Carpena, Patricia, Espinosa-Sanchez, Juan M., Aran, Ismael, Soto-Varela, Andres, Batuecas-Caletrio, Angel, Canlon, Barbara, May, Patrick, Cederroth, Christopher R., Lopez-Escamez, Jose A.

Συνεισφορές: Amanat,S, Gallego-Martinez,A, Perez-Carpena,P, Espinosa-Sanchez,JM, Lopez-Escamez,JA a Otology & Neurotology Group CTS495, Department of Genomic Medicine, GENYO-Centre for Genomics and Oncological Research-Pfizer/University of Granada/ Junta de Andalucía, PTS, Granada, Spain. Sollini,J, Cederroth,CR Hearing Sciences, Division of Clinical Neuroscience, School of Medicine, University of Nottingham, Nottingham, UK. Perez-Carpena,P, Lopez-Escamez,JA c Department of Otolaryngology, Instituto de Investigacion Biosanitaria, ibs.Granada, Hospital Universitario Virgen de las Nieves, Granada, Spain. Aran,I Department of Otolaryngology, Complexo Hospitalario de Pontevedra, Pontevedra, Spain. Soto-Varela,A e Division of Otoneurology, Department of Otorhinolaryngology, Complexo Hospitalario Universitario, Santiago de Compostela, Spain. Batuecas-Caletrio,A Department of Otolaryngology, Hospital Universitario de Salamanca, IBSAL Salamanca, Spain. Canlon,B, Cederroth,CR Laboratory of Experimental Audiology, Department of Physiology and Pharmacology, Karolinska Institute, Stockholm, Sweden. May,P Bioinformatics Core, Luxembourg Centre for System Biomedicine, University of Luxemburg, Esch-sur-Alzette, Luxembourg. Cederroth,CR National Institute for Health Research (NIHR) Nottingham Biomedical Research Centre, Nottingham University Hospitals NHS Trust, Ropewalk House, Nottingham, UK. Lopez-Escamez,JA Department of Surgery, Division of Otolaryngology, University of Granada, Granada, Spain, This study has been funded by H2020 MSCA-ITN-2016–722046, the H2020-SC1-2019-848261, and the GNP-182 GENDER-Net Co-Plus Fund (JALE and CRC). The project leading to these results has received funding from “la Caixa” Foundation (ID 100010434), under agreement LCF/PR/DE18/52010002 (JALE). This project is a part of European School of Interdisciplinary Tinnitus (ESIT) research and Sana Amanat is a PhD student in Biomedicine Program at the University of Granada. CRC received additional funding from Svenska Läkaresällskapet (SLS- 779681 ), Hörselforskningsfonden (503). The data handling for STOP and SweGen cohorts were enabled by resources provided by the Swedish National Infrastructure for Computing (SNIC) at UPPMAX partially funded by the Swedish Research Council through Grant agreement No. 2018-05973 . The time provided by JS was funded by the University of Nottingham, Nottingham Research Fellowship. PM was supported by the BMBF Treat-ION Grant ( 01GM1907 ) and the DFG Research Unit FOR2715 (FNR INTER/DFG/17/ 11583046 ).

Θεματικοί όροι: Tinnitus, Extreme phenotype, Axon initial segment, Exome sequencing, Meniere disease, Epilepsy, Genetic studies, Acúfeno, Fenotipo, Segmento inicial del axón, Secuenciación del exoma completo, Enfermedad de Meniere, Epilepsia, Estudios de asociación genética, Medical Subject Headings::Phenomena and Processes::Genetic Phenomena::Genetic Structures::Genome::Genome Components::Genes::Alleles, Medical Subject Headings::Organisms::Eukaryota::Animals, Medical Subject Headings::Anatomy::Nervous System::Central Nervous System::Brain, Medical Subject Headings::Disciplines and Occupations::Natural Science Disciplines::Biological Science Disciplines::Biology::Computational Biology, Medical Subject Headings::Check Tags::Female, Medical Subject Headings::Disciplines and Occupations::Natural Science Disciplines::Biological Science Disciplines::Biology::Genetics::Genetic Research::Gene Ontology, Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Genetic Techniques::Genetic Association Studies, Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans, Medical Subject Headings::Check Tags::Male, Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Rodentia::Muridae::Murinae::Mice, Medical Subject Headings::Phenomena and Processes::Genetic Phenomena::Phenotype, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Data Collection::Health Surveys::Health Status Indicators::Patient Acuity::Severity of Illness Index, Medical Subject Headings::Geographical Locations::Geographic Locations::Europe::Scandinavia::Sweden, Medical Subject Headings::Anatomy::Nervous System::Synapses, Medical Subject Headings::Diseases::Otorhinolaryngologic Diseases::Ear Diseases::Hearing Disorders::Tinnitus

Περιγραφή αρχείου: application/pdf; application/vnd.openxmlformats-officedocument.wordprocessingml.document

Relation: https://www.thelancet.com/journals/ebiom/article/PIIS2352-3964(21)00102-X/fulltext; Amanat S, Gallego-Martinez A, Sollini J, Perez-Carpena P, Espinosa-Sanchez JM, Aran I, et al. Burden of rare variants in synaptic genes in patients with severe tinnitus: An exome based extreme phenotype study. EBioMedicine. 2021 Apr;66:103309. doi:10.1016/j.ebiom.2021.103309.; http://hdl.handle.net/10668/4136; PMC8047463

Διαθεσιμότητα: http://hdl.handle.net/10668/4136
https://doi.org/10.1016/j.ebiom.2021.103309

Plaque-Associated Oligomeric Amyloid-Beta Drives Early Synaptotoxicity in APP/PS1 Mice Hippocampus: Ultrastructural Pathology Analysis

Συγγραφείς: Sanchez-Varo, Raquel, Sanchez-Mejias, Elisabeth, Fernandez-Valenzuela, Juan Jose, De Castro, Vanessa, Mejias-Ortega, Marina, Gomez-Arboledas, Angela, Jimenez, Sebastian, Sanchez-Mico, Maria Virtudes, Trujillo-Estrada, Laura, Moreno-Gonzalez, Ines, Baglietto-Vargas, David, Vizuete, Marisa, Davila, Jose Carlos, Vitorica, Javier, Gutierrez, Antonia

Συνεισφορές: Sanchez-Varo,R, Sanchez-Mejias,E, Fernandez-Valenzuela,JJ, De Castro,V, Mejias-Ortega,M, Gomez-Arboledas,A, Trujillo-Estrada,L, Moreno-Gonzalez,I, Baglietto-Vargas,D, Davila,JC, Gutierrez,A Departamento Biologia Celular, Genetica y Fisiologia, Instituto de Investigacion Biomedica de Malaga-IBIMA, Facultad de Ciencias, Universidad de Málaga, Málaga, Spain. Sanchez-Varo,R, Jimenez,S, Sanchez-Mico,MV, Vizuete,M, Vitorica,J, Gutierrez,A Centro de Investigación Biomedica en Red Sobre Enfermedades Neurodegenerativas (CIBERNED), Madrid, Spain. Sanchez-Varo,R Departamento Fisiologia Humana, Histologia Humana, Anatomia Patologica y Educacion Fisica y Deportiva, Facultad de Medicina, Universidad de Málaga, Málaga, Spain. Jimenez,S, Vitorica,J Departamento Bioquimica y Biologia Molecular, Facultad de Farmacia, Universidad de Sevilla, Seville, Spain. Jimenez,S, Vitorica,J Instituto de Biomedicina de Sevilla (IBiS), Hospital Universitario Virgen del Rocio CSIC/Universidad de Sevilla, Seville, Spain. Moreno-Gonzalez,I Department of Neurology, McGovern Medical School, UTHealth Science Center at Houston, Houston, TX, United States, This study was supported by the Instituto de Salud Carlos III (ISCiii) of Spain, co-financed by the FEDER funds from European Union, through grants PI18/01557 (to AG) and PI18/01556 (to JV), by the Junta de Andalucia Consejería de Economía y Conocimiento through grants UMA18-FEDERJA-211 (to AG), P18-RT-2233 (to AG), and US-1262734 (to JV) co-financed by Programa Operativo FEDER 2014–2020, by the Spanish Minister of Science and Innovation grant PID2019-108911RA-100 (to DB-V), Beatriz Galindo program BAGAL18/00052 (to DB-V) grant PID2019-107090RA-I00 (to IM-G), and Ramon y Cajal Program RYC-2017-21879 (to IM-G), and by the Malaga University grants B1-2019_07 (to ES-M) and B1-2019_06 (to IM-G). MM-O held a predoctoral contract from Malaga University and ES-M a postdoctoral contract (DOC_00251) from Junta de Andalucia.

Θεματικοί όροι: Alzheimer’s disease, Synaptic pathology, Hippocampus, Transgenic mice (Tg), Amyloid, Oligomers, Enfermedad de Alzheimer, Hipocampo, Ratones transgénicos, Amiloide, Morfolinos, Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans, Medical Subject Headings::Persons::Persons::Age Groups::Infant, Medical Subject Headings::Diseases::Pathological Conditions, Signs and Symptoms::Pathological Conditions, Anatomical::Plaque, Medical Subject Headings::Diseases::Nervous System Diseases::Neurodegenerative Diseases::Tauopathies::Alzheimer Disease, Medical Subject Headings::Anatomy::Nervous System::Neurons::Neurofibrils::Neurofibrillary Tangles, Medical Subject Headings::Anatomy::Nervous System::Synapses::Presynaptic Terminals, Medical Subject Headings::Anatomy::Nervous System::Neurons::Nerve Fibers::Axons::Neurites, Medical Subject Headings::Anatomy::Nervous System::Neuroglia::Astrocytes, Medical Subject Headings::Phenomena and Processes::Physical Phenomena::Elementary Particles::Electrons, Medical Subject Headings::Anatomy::Nervous System::Neuroglia::Microglia, Medical Subject Headings::Anatomy::Nervous System::Central Nervous System::Brain, Medical Subject Headings::Anatomy::Nervous System::Central Nervous System::Brain::Limbic System::Hippocampus, Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Diagnosis::Diagnostic Techniques and Procedures::Diagnostic Imaging::Microscopy::Microscopy, Electron

Περιγραφή αρχείου: application/pdf

Relation: https://www.frontiersin.org/articles/10.3389/fnins.2021.752594/full; Sanchez-Varo R, Sanchez-Mejias E, Fernandez-Valenzuela JJ, De Castro V, Mejias-Ortega M, Gomez-Arboledas A, et al. Plaque-Associated Oligomeric Amyloid-Beta Drives Early Synaptotoxicity in APP/PS1 Mice Hippocampus: Ultrastructural Pathology Analysis. Front Neurosci. 2021 Nov 4;15:752594.; http://hdl.handle.net/10668/4098; PMC8600261

Διαθεσιμότητα: http://hdl.handle.net/10668/4098
https://doi.org/10.3389/fnins.2021.752594

Extra Virgin Oil Polyphenols Improve the Protective Effects of Hydroxytyrosol in an In Vitro Model of Hypoxia-Reoxygenation of Rat Brain

Συγγραφείς: De La Cruz Cortés, José Pedro, Pérez de Algaba, Inmaculada, Martín-Aurioles, Esther, Arrebola, María Monsalud, Ortega-Hombrados, Laura, Rodríguez-Pérez, María Dolores, Fernández-Prior, María África, Bermúdez-Oria, Alejandra, Verdugo, Cristina, González-Correa, José Antonio

Συνεισφορές: De La Cruz Cortés,JP, Ortega-Hombrados,L, Rodríguez-Pérez,MD, Verdugo,C, González-Correa,JA Departmento de Farmacología, Facultad de Medicina, Instituto de Investigación Biomédica (IBIMA), Universidad de Málaga, Málaga, Spain. Pérez de Algaba,I Clinical Laboratory Department, Hospital Público de Montilla, Córdoba, Spain. Martín-Aurioles,E UGC La Roca, Distrito Sanitario Málaga-Guadalhorce, Málaga, Spain. Arrebola,MM UGC Laboratorio Clínico, Hospital de la Axarquía, AGSEMA, Málaga, Spain. Fernández-Prior,MÁ, Bermúdez-Oria,A Instituto de la Grasa, Consejo Superior de Investigaciones Científicas (CSIC), Seville, Spain., This study was supported in part by Consejería de Salud—Junta de Andalucía (Spain), Proyectos de Investigación en Salud (PI-0129-2017), and by Ministerio de Economía y Competitividad (Spain), Centro para el Desarrollo Tecnológico Industrial, Programa FEDER Interconecta Pluri Regional (PS17173. NUTRADAF, ITC-20161265)

Θεματικοί όροι: Hydroxytyrosol, Extra virgin olive oil, Polyphenols, In vitro, Neuroprotection, Aceite de oliva, Polifenoles, Neuroprotección, Medical Subject Headings::Organisms::Eukaryota::Animals, Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Rodentia::Muridae::Murinae::Rats, Medical Subject Headings::Chemicals and Drugs::Chemical Actions and Uses::Pharmacologic Actions::Molecular Mechanisms of Pharmacological Action::Antioxidants, Medical Subject Headings::Chemicals and Drugs::Organic Chemicals::Hydrocarbons::Hydrocarbons, Cyclic::Hydrocarbons, Aromatic::Benzene Derivatives::Phenols::Polyphenols, Aromatic::Benzene Derivatives::Phenols::Catechols::3-Methoxy-4-hydroxyphenylethanol, Medical Subject Headings::Chemicals and Drugs::Chemical Actions and Uses::Pharmacologic Actions::Physiological Effects of Drugs::Protective Agents::Neuroprotective Agents, Medical Subject Headings::Chemicals and Drugs::Inorganic Chemicals::Nitrogen Compounds::Nitrous Acid::Peroxynitrous Acid, Medical Subject Headings::Anatomy::Nervous System::Central Nervous System::Brain, Medical Subject Headings::Phenomena and Processes::Cell Physiological Phenomena::Cell Physiological Processes::Cell Death

Περιγραφή αρχείου: application/pdf

Relation: https://www.mdpi.com/2076-3425/11/9/1133/htm; De La Cruz Cortés JP, Pérez de Algaba I, Martín-Aurioles E, Arrebola MM, Ortega-Hombrados L, Rodríguez-Pérez MD, et al. Extra Virgin Oil Polyphenols Improve the Protective Effects of Hydroxytyrosol in an In Vitro Model of Hypoxia-Reoxygenation of Rat Brain. Brain Sci. 2021 Aug 26;11(9):1133; http://hdl.handle.net/10668/3815; PMC8471209

Διαθεσιμότητα: http://hdl.handle.net/10668/3815
https://doi.org/10.3390/brainsci11091133

Ultrasonographic Estimation of Total Brain Volume: 3D Reliability and 2D Estimation. Enabling Routine Estimation During NICU Admission in the Preterm Infant

Συγγραφείς: Benavente-Fernández, Isabel, Ruiz-González, Estefanía, Lubian-Gutiérrez, Manuel, Lubián-Fernández, Simón Pedro, Cabrales Fontela, Yunior, Roca-Cornejo, Cristina, Olmo-Duran, Pedro, Lubián-López, Simón Pedro

Συνεισφορές: Benavente-Fernández,I, Ruiz-González,E, Lubián-López,SP Division of Neonatology, Department of Paediatrics, Puerta del Mar University Hospital, Cádiz, Spain. Benavente-Fernández,I, Cabrales Fontela,Y, Lubián-López,SP Biomedical Research and Innovation Institute of Cádiz (INiBICA) Research Unit, Puerta del Mar University, Cádiz, Spain. Benavente-Fernández,I, Lubián-Fernández,SP, Roca-Cornejo,C, Olmo-Duran,P, Lubián-López,SP Area of Paediatrics, Department of Child and Mother Health and Radiology, Medical School, University of Cádiz, Cádiz, Spain. Lubian-Gutiérrez,M Department of Paediatrics, Puerta del Mar University Hospital, Cádiz, Spain., This work was supported by the 2017 (PI0052/2017) and 2019 (ITI-0019-2019) ITI-Cadiz integrated territorial initiative for biomedical research European Regional Development Fund (ERDF) 2014–2020. Andalusian Ministry of Health and Families, Spain.

Θεματικοί όροι: 3D ultrasonography, Preterm infant, Lineal measure, Brain volume, Magnetic resonance imaging, Neonatal intensive care unit, Neuroimaging, Ultrasonografía, Ultrasonografía prenatal, Recien nacido prematuro, Encéfalo, Imagen por resonancia magnética, Unidades de cuidado intensivo neonatal, Neuroimagen, Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans, Medical Subject Headings::Persons::Persons::Age Groups::Infant::Infant, Newborn, Medical Subject Headings::Persons::Persons::Age Groups::Infant, Medical Subject Headings::Health Care::Health Care Facilities, Manpower, and Services::Health Facilities::Hospital Units::Intensive Care Units::Intensive Care Units, Pediatric::Intensive Care Units, Neonatal, Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Diagnosis::Diagnostic Errors::Observer Variation, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Statistics as Topic::Confidence Intervals, Newborn::Infant, Premature, Diagnostic and Therapeutic Techniques and Equipment::Diagnosis::Diagnostic Techniques and Procedures::Diagnostic Imaging::Magnetic Resonance Imaging, Medical Subject Headings::Anatomy::Nervous System::Central Nervous System::Brain

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Relation: https://www.frontiersin.org/articles/10.3389/fped.2021.708396/full; Benavente-Fernández I, Ruiz-González E, Lubian-Gutiérrez M, Lubián-Fernández SP, Cabrales Fontela Y, Roca-Cornejo C, et al. Ultrasonographic Estimation of Total Brain Volume: 3D Reliability and 2D Estimation. Enabling Routine Estimation During NICU Admission in the Preterm Infant. Front Pediatr. 2021 Jul 22;9:708396; http://hdl.handle.net/10668/4321; PMC8339409

Διαθεσιμότητα: http://hdl.handle.net/10668/4321
https://doi.org/10.3389/fped.2021.708396

Citation Classics in Consumer Neuroscience, Neuromarketing and Neuroaesthetics: Identification and Conceptual Analysis

Συγγραφείς: Sánchez-Núñez, Pablo, Cobo, Manuel J., Vaccaro, Gustavo, Peláez, José Ignacio, Herrera-Viedma, Enrique

Συνεισφορές: Sánchez-Núñez,P Joint-PhD Programme in Communication, Department of Audiovisual Communication and Advertising, Faculty of Communication Sciences, Universidad de Málaga, Málaga, Spain. Sánchez-Núñez,P, Vaccaro,G, Peláez,JI Center for Applied Social Research (CISA), Universidad de Málaga, Málaga, Spain. Sánchez-Núñez,P, Peláez,JI Instituto de Investigación Biomédica de Málaga (IBIMA), Málaga, Spain. Cobo,MJ Department of Computer Science and Engineering, School of Engineering, Universidad de Cádiz, Cádiz, Spain. Vaccaro,G, Peláez,JI Department of Languages and Computer Science, Higher Technical School of Computer Engineering, Universidad de Málaga, Málaga, Spain. Herrera-Viedma,E Andalusian Research Institute on Data Science and Computational Intelligence, Department of Computer Science and AI, University of Granada, Granada, Spain., This work was supported by the Programa Operativo FEDER Andalucía 2014–2020 under Grant UMA 18-FEDERJA-148.

Θεματικοί όροι: Bibliometrix, Consumer behaviour, Consumer psychology, Consumer neuroscience, H-index, Highly cited papers (HCPs), Scientometrics, Science mapping analysis, SciMAT, Neuromarketing, Comportamiento del consumidor, Bibliometría, Neurociencia cognitiva, Psicología cognitiva, Factor de impacto de la revista, Artículo de revista, Medical Subject Headings::Information Science::Information Science::Computing Methodologies::Software, Medical Subject Headings::Information Science::Information Science::Communications Media::Publications::Bibliography as Topic::Bibliometrics, Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Diagnosis::Diagnostic Techniques and Procedures::Diagnostic Imaging::Magnetic Resonance Imaging, Medical Subject Headings::Psychiatry and Psychology::Behavior and Behavior Mechanisms::Motivation::Goals, Medical Subject Headings::Anatomy::Nervous System::Central Nervous System::Brain, Medical Subject Headings::Psychiatry and Psychology::Psychological Phenomena and Processes::Mental Processes::Cognition, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Chemistry Techniques, Analytical::Spectrum Analysis::Magnetic Resonance Spectroscopy, Medical Subject Headings::Information Science::Information Science::Communications Media::Publications::Bibliography as Topic::Bibliometrics::Journal Impact Factor, Medical Subject Headings::Publication Type::Publication Formats::Journal Article

Περιγραφή αρχείου: application/pdf

Relation: https://www.mdpi.com/2076-3425/11/5/548/htm; Sánchez-Núñez P, Cobo MJ, Vaccaro G, Peláez JI, Herrera-Viedma E. Citation Classics in Consumer Neuroscience, Neuromarketing and Neuroaesthetics: Identification and Conceptual Analysis. Brain Sci. 2021 Apr 27;11(5):548; http://hdl.handle.net/10668/4449; PMC8146570

Διαθεσιμότητα: http://hdl.handle.net/10668/4449
https://doi.org/10.3390/brainsci11050548

Generation of a humanized Aβ expressing mouse demonstrating aspects of Alzheimer's disease-like pathology

Συγγραφείς: Baglietto-Vargas, David, Forner, Stefania, Cai, Lena, Martini, Alessandra C., Trujillo-Estrada, Laura, Swarup, Vivek, Nguyen, Marie Minh Thu, Do Huynh, Kelly, Javonillo, Dominic I., Tran, Kristine Minh, Phan, Jimmy, Jiang, Shan, Kramár, Enikö A., Nuñez-Diaz, Cristina, Balderrama-Gutierrez, Gabriela, Garcia, Franklin, Childs, Jessica, Rodriguez-Ortiz, Carlos J., Garcia-Leon, Juan Antonio, Kitazawa, Masashi, Shahnawaz, Mohammad, Matheos, Dina P., Ma, Xinyi, Da Cunha, Celia, Walls, Ken C., Ager, Rahasson R., Soto, Claudio, Gutierrez, Antonia, Moreno-Gonzalez, Ines, Mortazavi, Ali, Tenner, Andrea J., MacGregor, Grant R., Wood, Marcelo, Green, Kim N., LaFerla, Frank M.

Συνεισφορές: Baglietto-Vargas,D, Forner,S, Cai,L, Martini,AC, Trujillo-Estrada,L, Swarup,V, Nguyen,MMT, Do Huynh,K, Javonillo,DI, Tran,KM, Phan,J, Kramár,EA, Garcia,F, Childs,J, Rodriguez-Ortiz,CJ, Kitazawa,M, Matheos,DP, Da Cunha,C, Walls,KC, Ager,RR, Tenner,AJ, Wood,M, Green,KM, LaFerla,FM Institute for Memory Impairments and Neurological Disorders, University of California, Irvine, CA, USA. Baglietto-Vargas,D, LaFerla,FM Department of Neurobiology and Behavior, University of California, Irvine, CA, USA. Baglietto-Vargas,D, Nuñez-Diaz,C, Garcia-Leon,JA, Gutierrez,A, Moreno-Gonzalez,I Department of Cell Biology, Genetic and Physiology, Faculty of Sciences, Instituto de Investigacion Biomedica de Malaga-IBIMA, Networking Research Center on Neurodegenerative Diseases (CIBERNED), University of Malaga, Malaga, Spain. Jiang,S, Balderrama-Gutierrez,G, Ma,X, Mortazavi,A, MacGregor,GR Department of Developmental and Cell Biology, University of California, Irvine, CA, USA. Rodriguez-Ortiz,CJ, Kitazawa,M Division of Occupational and Environmental Medicine, Department of Medicine. Center for Occupational and Environmental Health (COEH), University of California, Irvine, CA, USA. Shahnawaz,M, Soto,C, Moreno-Gonzale,I The Mitchell Center for Alzheimer’s Disease and Related Brain Disorders, Department of Neurology, McGovern Medical School, University of Texas Health Science Center at Houston, Houston, TX, USA. Tenner,AJ Department of Molecular Biology and Biochemistry, University of California, Irvine, CA, USA., This study was initiated by the generosity of Harry Bubb through Cure Alzheimer’s Fund CAF-50997 (F.M.L.). Additional support was from Alzheimer’s Association NIRG-15-363477 (D.B.V.), AARF-16-440760 (S.F.) and NIRG-394284 (I.M.G.), The Larry Hillblom Foundation 2013-A-016-FEL (D.B.V.) and 2016-A-016-FEL (A.C.M.), the National Institute of Health (NIH) NIH/NIA/NINDS AG027544 (F.M.L.), AG00538 (F.M.L.), AG54884 (F.M.L.), OD010420 (F.M.L.), U54 AG054349 (F.M.L., A.J.T.), AG049562 (C.S.) NS083801 (K.N.G.) and AG056768 (K.N.G.), BrightFocus Foundation grant A2015535S (F.M.L.), by Minister of Science and Innovation grant PID2019-108911RA-100 (D.B.V.), Beatriz Galindo program BAGAL18/00052 (D.B.V.) and Institute of Health Carlos III (ISCiii) grant PI18/01557 (A.G.) co-financed by FEDER funds from European Union, by American federation of aging research-AFAR young investigator award and UC Irvine startup funds (V.S.) and UCI MIND pilot project (D.B.V.). The UCI-ADRC is funded by NIH/NIA Grant P50 AG16573 (F.M.L.). Genetically modified hAβ-KI mice were generated by the UCI Transgenic Mouse Facility, a shared resource funded in part by the Chao Family Comprehensive Cancer Center Support Grant (P30CA062203) from the National Cancer Institute. We thank Drs. Malcolm Leissring and Rodrigo Medeiros for critically reading the manuscript.

Θεματικοί όροι: Periodic acid-schiff, Exon, Cognition, Mutation, Gene expression, Alzheimer disease, Reacción del ácido peryódico de Schiff, Exones, Cognición, Mutación, Expresión génica, Enfermedad de Alzheimer, Medical Subject Headings::Diseases::Nervous System Diseases::Neurodegenerative Diseases::Tauopathies::Alzheimer Disease, Medical Subject Headings::Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Peptides::Amyloid beta-Peptides, and Proteins::Proteins::Amyloid::Amyloidogenic Proteins::Amyloid beta-Protein Precursor, Medical Subject Headings::Organisms::Eukaryota::Animals, Medical Subject Headings::Anatomy::Nervous System::Central Nervous System::Brain, Medical Subject Headings::Check Tags::Female, Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Genetic Techniques::Gene Expression Profiling, Medical Subject Headings::Disciplines and Occupations::Natural Science Disciplines::Biological Science Disciplines::Biology::Genetics::Genetic Research::Gene Ontology, Medical Subject Headings::Phenomena and Processes::Genetic Phenomena::Genetic Structures::Base Sequence::Regulatory Sequences, Nucleic Acid::Gene Regulatory Networks, Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans, Medical Subject Headings::Check Tags::Male, Medical Subject Headings::Organisms::Eukaryota::Animals::Animal Population Groups::Animals, Laboratory::Animals, Inbred Strains::Mice

Περιγραφή αρχείου: application/pdf

Relation: https://www.nature.com/articles/s41467-021-22624-z; Baglietto-Vargas D, Forner S, Cai L, Martini AC, Trujillo-Estrada L, Swarup V, et al. Generation of a humanized Aβ expressing mouse demonstrating aspects of Alzheimer's disease-like pathology. Nat Commun. 2021 Apr 23;12(1):2421; http://hdl.handle.net/10668/4585; PMC8065162

Διαθεσιμότητα: http://hdl.handle.net/10668/4585
https://doi.org/10.1038/s41467-021-22624-z

Amyloid pathology arrangements in Alzheimer's disease brains modulate in vivo seeding capability

Συγγραφείς: Duran-Aniotz, Claudia, Moreno-Gonzalez, Ines, Gamez, Nazaret, Perez-Urrutia, Nelson, Vegas-Gomez, Laura, Soto, Claudio, Morales, Rodrigo

Συνεισφορές: Duran-Aniotz,C, Moreno-Gonzalez,I, Gamez,N, Perez-Urrutia,N, Soto,C, Morales,R Department of Neurology, The University of Texas Health Science Center at Houston, Fannin, St. Houston, USA. Duran-Aniotz,C Center for Social and Cognitive Neuroscience (CSCN), School of Psychology, Universidad Adolfo Ibanez, Santiago, Chile. Duran-Aniotz,C Latin American Brain Health Institute (BrainLat), Universidad Adolfo Ibanez, Santiago, Chile. Duran-Aniotz,C, Soto,C Universidad de los Andes, Facultad de Medicina, Las Condes, Santiago, Chile. Moreno-Gonzalez,I, Vegas-Gomez,L Department of Cell Biology, Faculty of Sciences, University of Malaga-IBIMA, Malaga, Spain. Moreno-Gonzalez,I Networking Research Center On Neurodegenerative Diseases (CIBERNED), Madrid, Spain. Moreno-Gonzalez,I, Morales,R Centro Integrativo de Biologia Y Quimica Aplicada (CIBQA), Universidad Bernardo O’Higgins, Santiago, Chile., This work was supported by a grants from the NIH (R56AG061878 and RF1AG059321) to RM and CS, the Alzheimer’s Association (AARGD-18–566576 to RM and 2018-AARG-591107 to CDA), ANID/FONDEF ID20I10152 and ANID/FONDECYT 1210622 to CDA, and PID2019-107090RA-100, 27565 2018 NARSAD and RYC-2017–21879 to IMG.

Θεματικοί όροι: Alzheimer’s disease, Amyloid-beta, Pathology, Prions, Strains, Enfermedad de alzheimer, beta-Amiloides, Patología, Priones, Medical Subject Headings::Persons::Persons::Age Groups::Adult::Aged, Medical Subject Headings::Persons::Persons::Age Groups::Adult::Aged::Aged, 80 and over, Medical Subject Headings::Diseases::Nervous System Diseases::Neurodegenerative Diseases::Tauopathies::Alzheimer Disease, Medical Subject Headings::Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Peptides::Amyloid beta-Peptides, Medical Subject Headings::Organisms::Eukaryota::Animals, Medical Subject Headings::Anatomy::Nervous System::Central Nervous System::Brain, Medical Subject Headings::Check Tags::Female, Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans, Medical Subject Headings::Check Tags::Male, Medical Subject Headings::Organisms::Eukaryota::Animals::Animal Population Groups::Animals, Genetically Modified::Mice, Transgenic, Medical Subject Headings::Persons::Persons::Age Groups::Adult::Middle Aged, and Proteins::Proteins::Prions, Medical Subject Headings::Diseases::Nervous System Diseases::Neurodegenerative Diseases::Prion Diseases, Medical Subject Headings::Diseases::Nutritional and Metabolic Diseases::Metabolic Diseases::Proteostasis Deficiencies::Amyloidosis, Medical Subject Headings::Phenomena and Processes::Genetic Phenomena::Phenotype

Περιγραφή αρχείου: application/pdf

Relation: https://actaneurocomms.biomedcentral.com/articles/10.1186/s40478-021-01155-0; Duran-Aniotz C, Moreno-Gonzalez I, Gamez N, Perez-Urrutia N, Vegas-Gomez L, Soto C, et al. Amyloid pathology arrangements in Alzheimer's disease brains modulate in vivo seeding capability. Acta Neuropathol Commun. 2021 Mar 30;9(1):56; http://hdl.handle.net/10668/3905; PMC8008576

Διαθεσιμότητα: http://hdl.handle.net/10668/3905
https://doi.org/10.1186/s40478-021-01155-0

Non-productive angiogenesis disassembles Aß plaque-associated blood vessels

Συγγραφείς: Alvarez-Vergara, Maria I., Rosales-Nieves, Alicia E., March-Diaz, Rosana, Rodriguez-Perinan, Guiomar, Lara-Ureña, Nieves, Ortega-de San Luis, Clara, Sanchez-Garcia, Manuel A., Martin-Bornez, Miguel, Gómez-Gálvez, Pedro, Vicente-Munuera, Pablo, Fernandez-Gomez, Beatriz, Marchena, Miguel A., Bullones-Bolanos, Andrea S., Davila, Jose C., Gonzalez-Martinez, Rocio, Trillo-Contreras, Jose L., Sanchez-Hidalgo, Ana C., del Toro, Raquel, Scholl, Francisco G., Herrera, Eloisa, Trepel, Martin, Körbelin, Jakob, Escudero, Luis M., Villadiego, Javier, Echevarria, Miriam, de Castro, Fernando, Gutierrez, Antonia, Rabano, Alberto, Vitorica, Javier, Pascual, Alberto

Συνεισφορές: Alvarez-Vergara,MI, Rosales-Nieves,AE, March-Diaz,R, Rodriguez-Perinan,G, Lara-Ureña,N, Ortega-de San Luis,C, Sanchez-Garcia,MA, Martin-Bornez,M, Gómez-Gálvez,P, Vicente-Munuera,P, Bullones-Bolanos,AS, Trillo-Contreras,JL, Sanchez-Hidalgo,AC, del Toro,R, Scholl,FG, Escudero,LM, Villadiego,J, Echevarria,M, Vitorica,J, Pascual,A Instituto de Biomedicina de Sevilla (IBiS), Hospital Universitario Virgen del Rocio/CSIC/Universidad de Sevilla, Seville, Spain. Gómez-Gálvez,P, Escudero,LM Department of Biología Celular, Universidad de Sevilla. Seville, Spain. Gómez-Gálvez,P, Davila,JC, Gutierrez,A, Vitorica,J Centro de Investigacion Biomedica en Red sobre Enfermedades Neurodegenerativas (CIBERNED), Madrid, Spain. Fernandez-Gomez,B, Marchena,MA, de Castro,F Grupo de Neurobiología del Desarrollo-GNDe, Instituto Cajal-CSIC, Madrid, Spain. Marchena,MA Departamento de Medicina, Facultad de Ciencias, Biomédicas y de la Salud, Universidad Europea de Madrid, Villaviciosa de Odón, Spain. Davila,JC, Gutierrez,A Department of Biologia Celular, Genetica y Fisiologia, Facultad de Ciencias, Instituto de Investigacion Biomedica de Malaga (IBIMA), Universidad de Malaga, Malaga, Spain. Gonzalez-Martinez,R, Herrera,E 7 Instituto de Neurociencias de Alicante, Consejo Superior de Investigaciones Científicas-Universidad Miguel Hernández (CSIC-UMH), Alicante, Spain. Trillo-Contreras,JL, Echevarria,M Department of Fisiología Médica y Biofisica, Universidad de Sevilla, Seville, Spain. del Toro,R Centro de Investigacion Biomedica en Red de Enfermedades Cardiovasculares (CIBER-CV), Madrid, Spain. Trepel,M Augsburg Medical Center, Department of Hematology and Oncology, Augsburg, Germany. Körbelin,J Section of Pneumology, Department of Oncology, Hematology and Stem Cell Transplantation, University Medical Center Hamburg-Eppendorf, Hamburg, Germany. Rabano,A Fundacion CIEN, Madrid, Spain. Vitorica,J Department of Bioquimica y Biologia Molecular, Facultad de Farmacia, Universidad de Sevilla, Seville, Spain. Ortega-de San Luis,L Present address: School of Biochemistry and Immunology, Trinity Biomedical Sciences Institute, Trinity College of Dublin, Dublin, Ireland. Sanchez-Garcia,MA Present address: Centre for Inflammation Research, Queen’s Medical Research Institute, University of Edinburgh, Edinburgh, UK. Alvarez-Vergara,MI, Rosales-Nieves,AE These authors contributed equally: Maria I. Alvarez-Vergara, Alicia E. Rosales-Nieves., A.E.R.-N. was the recipient of a JdlC-F fellowship from the Spanish Ministry of Economy, Industry, and Competitiveness (MINEICO) (FJCI-2015-23708), M.I.A.-V., N.L.-U., and C.O.-d.S.L. were the recipient of an FPU fellowship from Spanish Ministry of Education, Culture, and Sport (respectively, FPU15/02898, FPU14-02115, and AP2010‐1598), and R.M.-D. was the recipient of a “Sara Borrell” fellowship from ISCIII (CD09/0007). Work was supported by grants to A.P. by the Spanish MINEICO, ISCIII, and FEDER (SAF2012‐33816, SAF2015‐64111‐R, RTI2018-096629-B-100, SAF2017-90794-REDT, and PIE13/0004), by the regional Government of Andalusia (“Proyectos de Excelencia”, P12‐CTS‐2138 and P12‐CTS‐2232) co-funded by CEC and FEDER funds, and by the “Ayuda de Biomedicina 2018”, Fundación Domingo Martínez, J.Vitorica: Instituto de Salud Carlos III (ISCiii) of Spain, co-financed by FEDER funds from European Union (PI18/01556) by La Marató-TV3 Foundation grant 20141431, by CIBERNED (CB06/05/0094), and by Junta de Andalucia Consejería de Economía y Conocimiento through grant US-1262734, A.G.: Instituto de Salud Carlos III (ISCiii) of Spain, co-financed by FEDER funds from European Union, through grant PI18/01557, and by Junta de Andalucia Consejería de Economía y Conocimiento through grants UMA18-FEDERJA-211 and P18-RT-2233 co-financed by Programa Operativo FEDER 2014-2020. The authors thank Maria Llorens-Martin (CBM-Severo Ochoa, Madrid, Spain) for the generous gift of the human samples, Ralf H. Adams and Jose L. de la Pompa for providing the Cdh5-Cre

Θεματικοί όροι: Alzheimer disease, Brain, Endothelial cells, Presenilins, Péptidos beta-Amiloides, Plaque, amyloid, Blood vessels, Vascular malformations, Angiogenesis, Enfermedad de Alzheimer, Encéfalo, Células endoteliales, Presenilinas, Placa amiloide, Vasos sanguíneos, Malformaciones vasculares, Medical Subject Headings::Diseases::Nervous System Diseases::Neurodegenerative Diseases::Tauopathies::Alzheimer Disease, Medical Subject Headings::Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Peptides::Amyloid beta-Peptides, Medical Subject Headings::Organisms::Eukaryota::Animals, Medical Subject Headings::Anatomy::Cardiovascular System::Blood Vessels, Medical Subject Headings::Anatomy::Nervous System::Central Nervous System::Brain, Medical Subject Headings::Diseases::Animal Diseases::Disease Models, Animal, Medical Subject Headings::Anatomy::Cells::Epithelial Cells::Endothelial Cells, Medical Subject Headings::Check Tags::Female, Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Genetic Techniques::Gene Expression Profiling

Περιγραφή αρχείου: application/pdf; application/vnd.openxmlformats-officedocument.spreadsheetml.sheet

Relation: https://www.nature.com/articles/s41467-021-23337-z; Alvarez-Vergara MI, Rosales-Nieves AE, March-Diaz R, Rodriguez-Perinan G, Lara-Ureña N, Ortega-de San Luis C, et al. Non-productive angiogenesis disassembles Aß plaque-associated blood vessels. Nat Commun. 2021 May 25;12(1):3098; http://hdl.handle.net/10668/4516; PMC8149638

Διαθεσιμότητα: http://hdl.handle.net/10668/4516
https://doi.org/10.1038/s41467-021-23337-z

Association of Sedentary Behavior with Brain Structure and Intelligence in Children with Overweight or Obesity: The ActiveBrains Project

Συγγραφείς: Zavala-Crichton, Juan Pablo, Esteban-Cornejo, Irene, Solis-Urra, Patricio, Mora-Gonzalez, José, Cadenas-Sanchez, Cristina, Rodriguez-Ayllon, María, Migueles, Jairo H., Molina-Garcia, Pablo, Verdejo-Roman, Juan, Kramer, Arthur F., Hillman, Charles H., Erickson, Kirk I., Catena, Andrés, Ortega, Francisco B.

Συνεισφορές: Zavala-Crichton,JP, Esteban-Cornejo,I, Solis-Urra,P, Mora-Gonzalez,J, Cadenas-Sanchez,C, Rodriguez-Ayllon,M, Migueles,JH, Molina-Garcia,P, Ortega,FB PROFITH “PROmoting FITness and Health Through Physical Activity” Research Group, Sport and Health University Research Institute (iMUDS), Department of Physical and Sports Education, Faculty of Sport Sciences, University of Granada, Granada, Spain. Zavala-Crichton,JP Faculty of Education and Social Sciences, Universidad Andres Bello, Viña del Mar, Chile. Solis-Urra,P IRyS Research Group, School of Physical Education, Pontificia Universidad Católica de Valparaiso, Valparaiso, Chile. Mora-Gonzalez,J College of Health and Human Services, University of North Carolina at Charlotte, Charlotte, NC, USA. Cadenas-Sanchez,C MOVE-IT Research Group and Department of Physical Education, Faculty of Education Sciences University of Cádiz, Cádiz, Spain. Cadenas-Sanchez,C Biomedical Research and Innovation Institute of Cádiz (INiBICA) Research Unit, Puerta del Mar University Hospital University of Cádiz, Cádiz, Spain. Molina-Garcia,P Department of Rehabilitation Sciences, KU Leuven – University of Leuven, Leuven, Belgium. Verdejo-Roman,J Mind, Brain and Behavior Research Center (CIMCYC), University of Granada, Granada, Spain. Verdejo-Roman,J Laboratory of Cognitive and Computational Neuroscience (UCM-UPM), Center for Biomedical Technology (CTB), Pozuelo de Alarcón, Madrid, Spain. Kramer,AF, Hillman,CH Department of Psychology, Northeastern University, Boston, MA, USA. Kramer,AF Beckman Institute, University of Illinois at Urbana-Champaign, Champaign, IL, USA. Hillman,CH Department of Physical Therapy, Movement & Rehabilitation Sciences, Northeastern University, Boston, MA, USA. Erickson,KI Brain Aging & Cognitive Health Lab, Department of Psychology, University of Pittsburgh, Pittsburgh, PA, USA. Catena,A Department of Experimental Psychology, Mind, Brain and Behavior Research Centre (CIMCYC), University of Granada, Granada, Spain., This work study was supported by the Spanish Ministry of Economy and Competitiveness (DEP2013-47540, DEP2016-79512-R, and DEP2017-91544-EXP), the European Regional Development Fund (ERDF), European Union’s 2020 research and innovation program under grant agreement No. 667302 and the Alicia Koplowitz Foundation. This study was partially funded by the UGR Research and Knowledge Transfer Fund (PPIT) 2016, Excellence Actions Programme. Units of Scientific Excellence, Scientific Unit of Excellence on Excercise and Health (UCEES) and by the Regional Government of Andalusia, Regional Ministry of Economy, Knowledge, Entreprises and University and European Regional Development Fund (ERDF), ref. SOMM17/6107/UGR. In addition, this study was further supported by the SAMID III network, RETICS, funded by the PN I+D+I 2017-2021 (Spain), ISCIII-Sub-Directorate General for Research Assessment and Promotion, the European Regional Development Fund (ERDF) (Ref. RD16/0022), the EXERNET Research Network on Exercise and Health in Special Populations (DEP2005-00046/ACTI). IE-C is supported by a grant from the Alicia Koplowitz Foundation and by the Spanish Ministry of Economy and Competitiveness (RTI2018-095284-J-100)). CC-S is supported by the Regional Government of Andalusia, Integrated Territorial Initiative 2014-2020 of the province of Cádiz (PI-0002-2017) and the Spanish Ministry of Science and Innovation (FJC2018-037925-I). JHM and JM-G are supported by the Spanish Ministry of Education, Culture and Sport (FPU15/02645 and FPU14/06837, respectively). P-MG is supported by Horizon 2020 Framework Programme (Grant/ Award Number: 667302). PS-U was supported by a grant from CONICYT/BECAS Chile/72180543. JVR is supported by a grant from the Spanish Ministry of Science, Innovation and Universities (FJCI-2017-33396). This work is part of the Juan Pablo Zavala-Crichton Ph.D. Thesis conducted in the O_cial Doctoral Programme in Biomedicine of the University of Granada, Spain.

Θεματικοί όροι: Sedentariness, TV viewing, Magnetic resonance imaging, Brain, Cognition, Childhood, Obesity, Sedentary behavior, Imagen por resonancia magnética, Encéfalo, Cognición, Obesidad, Conducta sedentaria, Medical Subject Headings::Persons::Persons::Age Groups::Adolescent, Medical Subject Headings::Persons::Persons::Age Groups::Child, Medical Subject Headings::Anatomy::Nervous System::Central Nervous System::Brain, Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Epidemiologic Study Characteristics as Topic::Epidemiologic Studies::Cross-Sectional Studies, Medical Subject Headings::Phenomena and Processes::Physiological Phenomena::Body Constitution::Body Weights and Measures::Body Size::Body Weight::Overweight, Medical Subject Headings::Geographical Locations::Geographic Locations::Europe::Spain, Medical Subject Headings::Psychiatry and Psychology::Behavior and Behavior Mechanisms::Personality::Intelligence, Medical Subject Headings::Diseases::Nutritional and Metabolic Diseases::Nutrition Disorders::Overnutrition::Obesity, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Data Collection::Nutrition Assessment::Nutrition Surveys::Diet Surveys, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Data Collection::Questionnaires, Medical Subject Headings::Anthropology, Education, Sociology and Social Phenomena::Human Activities::Leisure Activities::Recreation::Play and Playthings::Video Games, Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans

Περιγραφή αρχείου: application/pdf

Relation: https://www.mdpi.com/2077-0383/9/4/1101/htm; Zavala-Crichton JP, Esteban-Cornejo I, Solis-Urra P, Mora-Gonzalez J, Cadenas-Sanchez C, Rodriguez-Ayllon M, et al. Association of Sedentary Behavior with Brain Structure and Intelligence in Children with Overweight or Obesity: The ActiveBrains Project. J Clin Med. 2020 Apr 12;9(4):1101; http://hdl.handle.net/10668/4124; PMC7230478

Διαθεσιμότητα: http://hdl.handle.net/10668/4124
https://doi.org/10.3390/jcm9041101

Characterization of an eutherian gene cluster generated after transposon domestication identifies Bex3 as relevant for advanced neurological functions

Συγγραφείς: Navas-Pérez, Enrique, Vicente-García, Cristina, Mirra, Serena, Burguera, Demian, Fernàndez-Castillo, Noèlia, Ferrán, José Luis, López-Mayorga, Macarena, Alaiz-Noya, Marta, Suárez-Pereira, Irene, Antón-Galindo, Ester, Ulloa, Fausto, Herrera-Úbeda, Carlos, Cuscó, Pol, Falcón-Moya, Rafael, Rodríguez-Moreno, Antonio, D'Aniello, Salvatore, Cormand, Bru, Marfany, Gemma, Soriano, Eduardo, Carrión, Ángel M., Carvajal, Jaime J., Garcia-Fernàndez, Jordi

Συνεισφορές: Navas-Pérez,E, Mirra,S, Burguera,D, Fernàndez-Castillo,N, Antón-Galindo,E, Herrera-Úbeda,C, Cormand,B, Marfany,G, Garcia-Fernàndez,J Department of Genetics, Microbiology and Statistics, Faculty of Biology, and Institut de Biomedicina (IBUB), University of Barcelona, Barcelona, Spain. Vicente-García,C, López-Mayorga,M, Carvajal,JJ Centro Andaluz de Biología del Desarrollo, CSIC-UPO-JA, Universidad Pablo de Olavide, Sevilla, Spain. Mirra,S, Ulloa,F, Soriano,E Department of Cell Biology, Physiology and Immunology, and Institute of Neurosciences, University of Barcelona, Barcelona, Spain. Mirra,S, Marfany,G Centro de Investigación Biomédica en Red de Enfermedades Raras (CIBERER), Instituto de Salud Carlos III (ISCIII), Madrid, Spain. Mirra,S, Soriano,E Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED), Instituto de Salud Carlos III (ISCIII), Madrid, Spain. Burguera,D Department of Zoology, Charles University, Prague, Czech Republic. Fernàndez-Castillo,N, Marfany,G Institut de Recerca Sant Joan de Déu (IR-SJD), Esplugues de Llobregat, Barcelona, Spain. Ferrán,JL Department of Human Anatomy, School of Medicine, University of Murcia and IMIB-Arrixaca Institute, Murcia, Spain. Alaiz-Noya,M, Suárez-Pereira,I, Falcón-Moya,R, Rodríguez-Moreno,A, Carrión,AM Department of Physiology, Anatomy and Cell Biology, Universidad Pablo de Olavide, Sevilla, Spain. Alaiz-Noya,M Present Address: Instituto de Neurociencias de Alicante (Universidad Miguel Hernández - Consejo Superior de Investigaciones Científicas), Alicante, Spain. Suárez-Pereira,I Present Address: Centro de Investigación Biomédica en Red de Salud Mental (CIBERSAM), Neuropsychopharmacology and psychobiology research group, UCA, INiBICA, Cádiz, Spain. Cuscó,P Genome Architecture, Gene Regulation, Stem Cells and Cancer Programme, Centre for Genomic Regulation (CRG), the Barcelona Institute of Science and Technology, Barcelona, Spain. Cuscó,P Universitat Pompeu Fabra (UPF), Barcelona, Spain. D'Aniello,S Department of Biology and Evolution of Marine Organisms, Stazione Zoologica Anton Dohrn, Naples, Italy. Soriano,E Institució Catalana de Recerca i Estudis Avançats (ICREA), Barcelona, Spain., Major financial support for this research was received from Spanish “Ministerio de Ciencia, Innovación y Universidades.” Grants BFU2015-68655-P and BFU2017-861152-P to J.G.F., RTI2018-100968-B-I00, 2017-SGR-738, H2020/2014-2020 under grant agreements n°667302, n°643051, and n°728018 to B.C., PGC2018-098229-B-I00 to J.L.F., BES-2016-077374 to E.A.-G., CVI-7290 Junta de Andalucía to A.R.M., SAF2016-80937-R (Ministerio de Economía y Competitividad/FEDER) to G.M., Institutional Grant MDM-2016-0687 (Maria de Maeztu Excellence Unit, Department of Gene Regulation and Morphogenesis at CABD) and BFU2017-83150-P to J.J.C, BFU2017-89780-R and P12-CTS-2257 to A.M.C. and SAF2016-76340-R and María de Maeztu Excellence Unit, Institute of Neurosciences to E.S. E.N.P. held an FPI pre-doctoral fellowship (Spanish “Ministerio de Ciencia, Innovación y Universidades”). S.M. was first supported by a contract with the “Centro de Investigación Biomédica en Enfermedades Neurodegenerativas,” and later by “Centro de Investigación Biomédica en Red de Enfermedades Raras” (CIBERER). N.F.C. is also under contract by CIBERER. This study makes use of data generated by the DECIPHER community. A full list of centres who contributed to the generation of the data is available at http://decipher.sanger.ac.uk and via email from decipher@sanger.ac.uk. Funding for the project was provided by the Wellcome Trust.

Θεματικοί όροι: Genetic novelty, Transposon domestication, Bex3, Tceal, Placental mammals, Gene cluster, Neurodevelopmental disorders, mTOR, Autism spectrum disorder, Euterios, Familia de multigenes, Trastornos del neurodesarrollo, Serina-treonina quinasas TOR, Trastorno del espectro autista, Medical Subject Headings::Organisms::Eukaryota::Animals, Medical Subject Headings::Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Proteins::Intracellular Signaling Peptides and Proteins::Apoptosis Regulatory Proteins, Medical Subject Headings::Psychiatry and Psychology::Mental Disorders::Mental Disorders Diagnosed in Childhood::Child Development Disorders, Pervasive::Autistic Disorder, Medical Subject Headings::Anatomy::Nervous System::Central Nervous System::Brain, Medical Subject Headings::Phenomena and Processes::Genetic Phenomena::Genetic Processes::Gene Expression Regulation::Epigenesis, Genetic::Gene Silencing::CRISPR-Cas Systems, and Proteins::Proteins::DNA-Binding Proteins, Medical Subject Headings::Phenomena and Processes::Biological Phenomena::Biological Processes::Biological Evolution::Evolution, Molecular, Medical Subject Headings::Check Tags::Female, Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans, Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Rodentia::Muridae::Murinae::Mice, Medical Subject Headings::Organisms::Eukaryota::Animals::Animal Population Groups::Animals

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Relation: https://genomebiology.biomedcentral.com/articles/10.1186/s13059-020-02172-3; Navas-Pérez E, Vicente-García C, Mirra S, Burguera D, Fernàndez-Castillo N, Ferrán JL, et al. Characterization of an eutherian gene cluster generated after transposon domestication identifies Bex3 as relevant for advanced neurological functions. Genome Biol. 2020 Oct 26;21(1):267; http://hdl.handle.net/10668/3788; PMC7586669

Διαθεσιμότητα: http://hdl.handle.net/10668/3788
https://doi.org/10.1186/s13059-020-02172-3

C9orf72-associated SMCR8 protein binds in the ubiquitin pathway and with proteins linked with neurological disease

Συγγραφείς: Goodier, John L., Soares, Alisha O., Pereira, Gavin C., DeVine, Lauren R., Sanchez, Laura, Cole, Robert N., García-Pérez, Jose Luis

Συνεισφορές: Goodier,JL, Soares,AO, Pereira,GC McKusick-Nathans Department of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA. DeVine,LR, Cole,RN Mass Spectrometry and Proteomics Facility, Department of Biological Chemistry, Johns Hopkins University School of Medicine, Baltimore, MD, USA. Sanchez,L, García-Pérez,JL GENYO. Centre for Genomics and Oncological Research: Pfizer, University of Granada, Andalusian Regional Government, Granada, Spain. García-Pérez,JL MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine (IGMM), University of Edinburgh, Western General Hospital, Edinburgh, UK., JLG was supported by grants from the NIH National Institute of Neurological Disorders and Stroke (1R03NS087290–01), the NIH Eunice Kennedy Shriver National Institute of Child Health and Human Development (R21HD083915-01A1), and the ALS Therapy Alliance (2013-F-067). The JLGP lab acknowledges funding from the European Research Council (ERC-Consolidator ERC-STG-2012-309433), the MINECO-FEDER (SAF2017–89745-R), and The Wellcome Trust-University of Edinburgh Institutional Strategic Support Fund (ISFF2). RNC was partially supported by NIH/NCATS grant UL1 TR003098.

Θεματικοί όροι: Amyotrophic lateral sclerosis, Autophagy, Biomarker, Mass spectrometry, Proteasome, Stress granules, Ubiquitin, Esclerosis amiotrófica lateral, Autofagia, Biomarcadores, Espectrometría de masas, Complejo de la endopetidasa proteasomal, Ubiquitina, Proteína C9orf72, Medical Subject Headings::Diseases::Nervous System Diseases::Central Nervous System Diseases::Spinal Cord Diseases::Amyotrophic Lateral Sclerosis, Medical Subject Headings::Anatomy::Nervous System::Central Nervous System::Brain, Medical Subject Headings::Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Proteins::Carrier Proteins, Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans, Medical Subject Headings::Chemicals and Drugs::Biological Factors::Biological Markers, Medical Subject Headings::Phenomena and Processes::Cell Physiological Phenomena::Cell Physiological Processes::Cell Death::Autophagy, Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Chemistry Techniques, Analytical::Mass Spectrometry, Medical Subject Headings::Chemicals and Drugs::Macromolecular Substances::Multiprotein Complexes::Multienzyme Complexes::Proteasome Endopeptidase Complex, and Proteins::Proteins::Ubiquitins::Ubiquitin

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Relation: https://actaneurocomms.biomedcentral.com/articles/10.1186/s40478-020-00982-x; Goodier JL, Soares AO, Pereira GC, DeVine LR, Sanchez L, Cole RN, et al. C9orf72-associated SMCR8 protein binds in the ubiquitin pathway and with proteins linked with neurological disease. Acta Neuropathol Commun. 2020 Jul 16;8(1):110; http://hdl.handle.net/10668/3677; PMC7364817

Διαθεσιμότητα: http://hdl.handle.net/10668/3677
https://doi.org/10.1186/s40478-020-00982-x

Whole-exome sequencing of 81 individuals from 27 multiply affected bipolar disorder families

Συγγραφείς: Forstner, Andreas J., Fischer, Sascha B., Schenk, Lorena M., Strohmaier, Jana, Maaser-Hecker, Anna, Reinbold, Céline S., Sivalingam, Sugirthan, Hecker, Julian, Streit, Fabian, Degenhardt, Franziska, Witt, Stephanie H., Schumacher, Johannes, Thiele, Holger, Nürnberg, Peter, Guzman-Parra, José, Orozco Diaz, Guillermo, Auburger, Georg, Albus, Margot, Borrmann-Hassenbach, Margitta, González, Maria José, Gil Flores, Susana, Cabaleiro Fabeiro, Francisco J., del Río Noriega, Francisco, Perez Perez, Fermin, Haro González, Jesus, Rivas, Fabio, Mayoral, Fermin, Bauer, Michael, Pfennig, Andrea, Reif, Andreas, Herms, Stefan, Hoffmann, Per, Pirooznia, Mehdi, Goes, Fernando S., Rietschel, Marcella, Nöthen, Markus M., Cichon, Sven

Συνεισφορές: Forstner,AJ, Schumacher,J Centre for Human Genetics, University of Marburg, Marburg, Germany. Forstner,AJ, Schenk,LM, Maaser-Hecker,A, Sivalingam,S, Degenhardt,F, Schumacher,J, Herms,S, Hoffmann,P, Nöthen,MM, Cichon,S Institute of Human Genetics, University of Bonn, School of Medicine & University Hospital Bonn, Bonn, Germany. Forstner,AJ, Fischer,SB, Reinbold,CS, Cichon,S Department of Biomedicine, University of Basel, Basel, Switzerland. Forstner,AJ Department of Psychiatry (UPK), University of Basel, Basel, Switzerland. Fischer,SB, Cichon,S Institute of Medical Genetics and Pathology, University Hospital Basel, Basel, Switzerland. Strohmaier,J, Streit,F, Witt,SH, Rietschel,M Department of Genetic Epidemiology in Psychiatry, Central Institute of Mental Health, Medical Faculty Mannheim, University of Heidelberg, Mannheim, Germany. Strohmaier,J SRH University Heidelberg, Academy for Psychotherapy, Heidelberg, Germany. Reinbold,CS Center for Lifespan Changes in Brain and Cognition (LCBC), Department of Psychology, University of Oslo, Oslo, Norway. Hecker,J Department of Biostatistics, Harvard T.H. Chan School of Public Health, Boston, MA, USA. Thiele,H, Nürnberg,P Cologne Center for Genomics, University of Cologne, Cologne, Germany. Guzman-Parra,J, González,MJ Department of Mental Health, University Regional Hospital of Málaga, Institute of Biomedicine of Málaga (IBIMA), Málaga, Spain. Orozco Diaz,G Unidad de Gestión Clínica del Dispositivo de Cuidados Críticos y Urgencias del Distrito Sanitario Málaga - Coin- Gudalhorce, Málaga, Spain. Auburger,G Experimental Neurology, Department of Neurology, Goethe University Hospital, Frankfurt am Main, Germany. Albus,M, Borrmann-Hassenbach,M Isar Amper Klinikum München Ost, kbo, Haar, Germany. Gil Flores,S Department of Mental Health, University Hospital of Reina Sofia, Cordoba, Spain. Cabaleiro Fabeiro,FJ Department of Mental Health, Hospital of Jaén, Jaén, Spain. del Río Noriega,F Department of Mental Health, Hospital of Jerez de la Frontera, Jerez de la Frontera, Spain. Perez Perez,F Department of Mental Health, Hospital of Puerto Real, Cádiz, Spain. Haro González,J Department of Mental Health, Hospital Punta de Europa, Algeciras, Spain. Rivas,F, Mayoral,F Department of Psychiatry, Carlos Haya Regional University Hospital, Malaga, Spain. Bauer,M, Pfennig,A Department of Psychiatry and Psychotherapy, Medical Faculty, University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany. Reif,A Department of Psychiatry, Psychosomatic Medicine and Psychotherapy, University Hospital Frankfurt am Main, Frankfurt am Main, Germany. Hoffmann,P, Cichon,S Institute of Neuroscience and Medicine (INM-1), Research Center Jülich, Jülich, Germany. Pirooznia,M, Goes,FS Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, MD, USA, The study was supported by the German Federal Ministry of Education and Research (BMBF) through the Integrated Network IntegraMent (Integrated Understanding of Causes and Mechanisms in Mental Disorders), under the auspices of the e:Med Programme (grant 01ZX1314A/01ZX1614A to M.M.N. Forstner Translational Psychiatry (2020) 10:57 Page 8 of 10 and S.C., grant 01ZX1314G/01ZX1614G to M.R.) and through ERA-NET NEURON, “SynSchiz—Linking synaptic dysfunction to disease mechanisms in schizophrenia—a multilevel investigation“ (01EW1810 to MR). The study was also supported by the German Research Foundation (DFG, grant FOR2107, RI908/11-1 and RI908/11–2 to M.R., NO246/10-1 and NO 246/10-2 to M.M.N.), and the Swiss National Science Foundation (SNSF, grant 156791 to S.C.). M.M.N. is a member of the DFG-funded Excellence-Cluster ImmunoSensation.

Θεματικοί όροι: Whole exome sequencing, Bipolar disorder, Neuropsychiatry, Genetic predisposition to disease, Secuenciación del exoma completo, Trastorno bipolar, Neuropsiquiatría, Predisposición genética a la enfermedad, Medical Subject Headings::Phenomena and Processes::Genetic Phenomena::Genetic Structures::Genome::Exome, Medical Subject Headings::Phenomena and Processes::Genetic Phenomena::Genotype::Genetic Predisposition to Disease, Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans, Medical Subject Headings::Psychiatry and Psychology::Mental Disorders::Schizophrenia and Disorders with Psychotic Features::Schizophrenia, Medical Subject Headings::Psychiatry and Psychology::Mental Disorders::Mood Disorders::Affective Disorders, Psychotic::Bipolar Disorder, Medical Subject Headings::Psychiatry and Psychology::Mental Disorders::Mental Disorders Diagnosed in Childhood::Child Development Disorders, Pervasive::Autistic Disorder, Medical Subject Headings::Geographical Locations::Geographic Locations::Europe::Spain, Medical Subject Headings::Geographical Locations::Geographic Locations::Europe::Germany, Medical Subject Headings::Phenomena and Processes::Genetic Phenomena::Inheritance Patterns::Penetrance, Medical Subject Headings::Anatomy::Nervous System::Central Nervous System::Brain

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Relation: https://www.nature.com/articles/s41398-020-0732-y; Forstner AJ, Fischer SB, Schenk LM, Strohmaier J, Maaser-Hecker A, Reinbold CS, et al. Whole-exome sequencing of 81 individuals from 27 multiply affected bipolar disorder families. Transl Psychiatry. 2020 Feb 4;10(1):57; http://hdl.handle.net/10668/3860; PMC7026119

Διαθεσιμότητα: http://hdl.handle.net/10668/3860
https://doi.org/10.1038/s41398-020-0732-y

Physical fitness and white matter microstructure in children with overweight or obesity: the ActiveBrains project

Συγγραφείς: Rodriguez-Ayllon, M., Esteban-Cornejo, I., Verdejo-Román, J., Muetzel, R. L., Mora-Gonzalez, J., Cadenas-Sanchez, C., Plaza-Florido, A., Molina-Garcia, P., Kramer, A. F., Catena, A., Ortega, F. B.

Συνεισφορές: Rodriguez-Ayllon,M, Esteban-Cornejo,I, Mora-Gonzalez,J, Cadenas-Sanchez,C, Plaza-Florido,A, Molina-Garcia,P, Ortega,FB PROFITH “Promoting Fitness and Health Through Physical Activity” Research Group, Department of Physical and Sports Education, Faculty of Sport Sciences, University of Granada, Granada, Spain. Verdejo-Román,J, Catena,A The Brain, Mind and Behavior Research Center, University of Granada (CIMCYC-UGR), Granada, Spain. Verdejo-Román,J Laboratory of Cognitive and Computational Neuroscience (UCM‑UPM), Centre for Biomedical Technology (CTB), Madrid, Spain. Muetzel,RL Department of Child and Adolescent Psychiatry, Erasmus MC – Sophia Children’s Hospital, Rotterdam, The Netherlands. Muetzel,RL Department of Epidemiology, Erasmus MC, Rotterdam, The Netherlands. Mora-Gonzalez,J College of Health and Human Services, University of North Carolina at Charlotte, Charlotte, NC, USA. Cadenas-Sanchez,C MOVE‑IT Research Group and Department of Physical Education, Faculty of Education Sciences, University of Cádiz, Cádiz, Spain. Cadenas-Sanchez,C Biomedical Research and Innovation Institute of Cádiz (INiBICA) Research Unit, Puerta del Mar University Hospital, University of Cádiz, Cádiz, Spain. Kramer,AF Center for Cognitive and Brain Health, Department of Psychology, Northeastern University, Boston, MA, USA. Kramer,AF Beckman Institute, University of Illinois at Urbana-Champaign, IL, USA. Catena,A Department of Clinical Psychology, University of Granada, Granada, Spain. Ortega,FB Department of Biosciences and Nutrition, Karolinska Institutet, Group MLO, Huddinge, Sweden., This work study was supported by the Spanish Ministry of Economy and Competitiveness (DEP2013-47540, DEP2016-79512-R, and DEP2017-91544-EXP), the European Regional Development Fund (ERDF)”, the European Commission (No 667302), and the Alicia Koplowitz Foundation. Tis study was partially funded by the University of Granada, Research and Knowledge Transfer Fund (PPIT) 2016, the Excellence Actions Programme: Units of Excellence, Scientifc Unit of Excellence on Exercise and Health (UCEES), the Andalusian Regional Government, the Regional Ministry of Economy, Knowledge, Entreprises and University, and the European Regional Development Fund (ERDF), ref. SOMM17/6107/UGR. IE-C is supported by the Spanish Ministry of Economy and Competitiveness (RTI2018-095284-J-100). In addition, this study was further supported by the SAMID III network, RETICS, funded by the PN I+D+I 2017-2021 (Spain). JM-G and AP-F are supported by the Spanish Ministry of Education, Culture and Sport (FPU14/06837, FPU 16/02760, respectively). CC-S is supported by the Government of Andalusian, Integrated Territorial Initiative 2014-2020 for the province of Cádiz (PI-0002-2017). JVR is supported by a grant from the Spanish Ministry of Science, Innovation and Universities (FJCI-2017-33396).

Θεματικοί όροι: Anisotropy, Obesity, Overweight, Children, Brain, Physical ftness, Anisotropía, Obesidad, Sobrepeso, Encéfalo, Andalucía, Medical Subject Headings::Phenomena and Processes::Physical Phenomena::Optical Phenomena::Anisotropy, Medical Subject Headings::Persons::Persons::Age Groups::Child, Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Epidemiologic Study Characteristics as Topic::Epidemiologic Studies::Cross-Sectional Studies, Diagnostic and Therapeutic Techniques and Equipment::Diagnosis::Diagnostic Techniques and Procedures::Diagnostic Techniques, Neurological::Neuroimaging::Diffusion Tensor Imaging, Medical Subject Headings::Check Tags::Female, Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans, Medical Subject Headings::Check Tags::Male, Diagnostic and Therapeutic Techniques and Equipment::Diagnosis::Diagnostic Techniques and Procedures::Physical Examination::Muscle Strength, Medical Subject Headings::Diseases::Nutritional and Metabolic Diseases::Nutrition Disorders::Overnutrition::Obesity, Medical Subject Headings::Diseases::Pathological Conditions, Signs and Symptoms::Signs and Symptoms::Body Weight::Overweight, Medical Subject Headings::Anthropology, Education, Sociology and Social Phenomena::Human Activities::Leisure Activities::Recreation::Sports::Athletic Performance::Physical Fitness, Medical Subject Headings::Health Care::Health Services Administration::Quality of Health Care::Program Evaluation::Benchmarking, Medical Subject Headings::Anatomy::Nervous System::Central Nervous System::Brain, Medical Subject Headings::Anatomy::Nervous System::Central Nervous System::Brain::Prosencephalon::Telencephalon::Cerebrum::Cerebral Cortex::Frontal Lobe

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Relation: https://www.nature.com/articles/s41598-020-67996-2; Rodriguez-Ayllon M, Esteban-Cornejo I, Verdejo-Román J, Muetzel RL, Mora-Gonzalez J, Cadenas-Sanchez C, et al. Physical fitness and white matter microstructure in children with overweight or obesity: the ActiveBrains project. Sci Rep. 2020 Jul 27;10(1):12469; http://hdl.handle.net/10668/4367; PMC7385257

Διαθεσιμότητα: http://hdl.handle.net/10668/4367
https://doi.org/10.1038/s41598-020-67996-2

Increased mitochondrial calcium levels associated with neuronal death in a mouse model of Alzheimer's disease

Συγγραφείς: Calvo-Rodriguez, Maria, Hou, Steven S., Snyder, Austin C., Kharitonova, Elizabeth K., Russ, Alyssa N., Das, Sudeshna, Fan, Zhanyun, Muzikansky, Alona, Garcia-Alloza, Monica, Serrano-Pozo, Alberto, Hudry, Eloise, Bacskai, Brian J.

Συνεισφορές: Calvo-Rodriguez,M, Hou,SS, Snyder,AC, Kharitonova,EK, Russ,AN, Das,S, Fan,Z, Serrano-Pozo,A, Hudry,E, Bacskai,BJ Department of Neurology, Massachusetts General Hospital and Harvard Medical School, MA, USA. Muzikansky,A Department of Biostatistics, Harvard School of Public Health, Boston, MA, USA. Garcia-Alloza,M Division of Physiology, School of Medicine, Instituto de Investigacion Biomedica de Cadiz (INIBICA), Universidad de Cadiz, Cadiz, Spain., This work was supported by NIHR01AG0442603, S10 RR025645 and R56AG060974 (BJB), and by the Tosteson & Fund for Medical Discovery and the BrightFocus Foundation A2019488F (MCR). MSBB study was supported by the grants AG046170, AG054014, AG057440 and AG057907 from the NIH/National Institute on Aging (NIA). A.S.-P. was supported by the Alzheimer’s Association (AACF-17-524184) and the National Institute for Neurodegenerative Diseases and Stroke (NINDS R25NS065743).

Θεματικοί όροι: Mitochondria, Calcium, Cell death, Amyloid, Brain, Genes, Microscopy, Alzheimer disease, Lead, Mitocondrias, Calcio, Muerte celular, Amiloide, Encéfalo, Microscopía, Enfermedad de Alzheimer, Plomo, Medical Subject Headings::Diseases::Nervous System Diseases::Neurodegenerative Diseases::Tauopathies::Alzheimer Disease, Medical Subject Headings::Organisms::Eukaryota::Animals, Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Genetic Techniques::Molecular Probe Techniques::Blotting, Western, Medical Subject Headings::Anatomy::Nervous System::Central Nervous System::Brain, Medical Subject Headings::Chemicals and Drugs::Inorganic Chemicals::Elements::Metals, Alkaline Earth::Calcium, Medical Subject Headings::Anatomy::Cells::Cells, Cultured, Medical Subject Headings::Anatomy::Cells::Cellular Structures::Intracellular Space::Cytoplasm::Cytosol, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Immunologic Techniques::Immunohistochemistry, Medical Subject Headings::Check Tags::Male

Περιγραφή αρχείου: application/pdf

Relation: https://www.nature.com/articles/s41467-020-16074-2; Calvo-Rodriguez M, Hou SS, Snyder AC, Kharitonova EK, Russ AN, Das S, et al. Increased mitochondrial calcium levels associated with neuronal death in a mouse model of Alzheimer's disease. Nat Commun. 2020 May 1;11(1):2146.; http://hdl.handle.net/10668/3567; PMC7195480

Διαθεσιμότητα: http://hdl.handle.net/10668/3567
https://doi.org/10.1038/s41467-020-16074-2

Clinical and Neurochemical Effects of Transcranial Magnetic Stimulation (TMS) in Multiple Sclerosis: A Study Protocol for a Randomized Clinical Trial

Συγγραφείς: Agüera, Eduardo, Caballero-Villarraso, Javier, Feijóo, Montserrat, Escribano, Begoña M., Conde, Cristina, Bahamonde, María C., Giraldo, Ana I., Paz-Rojas, Elier, Túnez, Isaac

Συνεισφορές: Agüera,E, Caballero-Villarraso,J, Feijóo,M, Escribano,BM, Conde,C, Bahamonde,MC, Giraldo,AI, Paz-Rojas,E, Túnez,I Instituto Maimónides de Investigación Biomédica de Córdoba (IMIBIC), Córdoba, Spain. Agüera,E, Bahamonde,MC Unidad de Gestión Clínica de Neurología, Hospital Universitario Reina Sofía, Córdoba, Spain. Caballero-Villarraso,J, Túnez,I Departmento de Bioquímica y Biología Molecular, Facultad de Medicina y Enfermería, Universidad de Córdoba, Córdoba, Spain. Caballero-Villarraso,J Unidad de Gestión Clínica de Análisis Clínicos, Hospital Universitario Reina Sofía, Córdoba, Spain. Escribano,BM Departamento de Biología Celular, Fisiología e Inmunología, Universidad de Córdoba, Córdoba, Spain. Paz-Rojas,E Canvax Biotech S.L., Córdoba, Spain.

Θεματικοί όροι: Clinical trial, Multiple sclerosis, Neurodegenerative diseases, Transcranial magnetic stimulation, Neuroplasticity, Neurochemistry, Ensayo clínico, Esclerosis múltiple, Enfermedades neurodegenerativas, Estimulación magnética transcraneal, Plasticidad neuronal, Neuroquímica, Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans, Medical Subject Headings::Organisms::Eukaryota::Animals, Medical Subject Headings::Diseases::Nervous System Diseases::Autoimmune Diseases of the Nervous System::Demyelinating Autoimmune Diseases, CNS::Multiple Sclerosis, CNS::Multiple Sclerosis::Multiple Sclerosis, Relapsing-Remitting, Medical Subject Headings::Diseases::Nervous System Diseases::Neurodegenerative Diseases, Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Epidemiologic Research Design::Single-Blind Method, Medical Subject Headings::Diseases::Nervous System Diseases::Central Nervous System Diseases::Movement Disorders::Dyskinesias::Chorea, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Epidemiologic Study Characteristics as Topic::Feasibility Studies, Medical Subject Headings::Diseases::Nervous System Diseases::Central Nervous System Diseases::Movement Disorders::Parkinsonian Disorders::Parkinson Disease, Medical Subject Headings::Health Care::Environment and Public Health::Public Health::Epidemiologic Methods::Epidemiologic Research Design::Random Allocation, Medical Subject Headings::Anatomy::Nervous System::Central Nervous System::Brain, Medical Subject Headings::Phenomena and Processes::Physical Phenomena::Magnetic Phenomena::Electromagnetic Phenomena, Medical Subject Headings::Psychiatry and Psychology::Behavior and Behavior Mechanisms::Psychology, Social::Family

Περιγραφή αρχείου: application/pdf

Relation: https://www.frontiersin.org/articles/10.3389/fneur.2020.00750/; Agüera E, Caballero-Villarraso J, Feijóo M, Escribano BM, Conde C, Bahamonde MC, et al. Clinical and Neurochemical Effects of Transcranial Magnetic Stimulation (TMS) in Multiple Sclerosis: A Study Protocol for a Randomized Clinical Trial. Front Neurol. 2020 Aug 11;11:750; http://hdl.handle.net/10668/4549; PMC7431867

Διαθεσιμότητα: http://hdl.handle.net/10668/4549
https://doi.org/10.3389/fneur.2020.00750

Neurocognitive signatures of phonemic sequencing in expert backward speakers

Συγγραφείς: Torres-Prioris, María José, López-Barroso, Diana, Càmara, Estela, Fittipaldi, Sol, Sedeño, Lucas, Ibáñez, Agustín, Berthier, Marcelo L., García, Adolfo M.

Συνεισφορές: Torres-Prioris,MJ, López-Barroso,D, Berthier,ML Cognitive Neurology and Aphasia Unit, Centro de Investigaciones Médico‑Sanitarias, Instituto de Investigación Biomédica de Málaga (IBIMA), University of Malaga, Malaga, Spain. Torres-Prioris,MJ, López-Barroso,D Area of Psychobiology, Faculty of Psychology and Speech Therapy, University of Malaga, Malaga, Spain. Càmara,E Cognition and Brain Plasticity Unit, Bellvitge Biomedical Research Institute (IDIBELL), L’Hospitalet de Llobregat, Barcelona, Spain. Fittipaldi,S, Ibáñez,A, García,AM Universidad de San Andrés, Victoria, Buenos Aires, Argentina. Fittipaldi,S, Sedeño,L, García,AM National Scientific and Technical Research Council (CONICET), Buenos Aires, Argentina. Ibáñez,A Universidad Autónoma del Caribe, Barranquilla, Colombia. Ibáñez,A Center for Social and Cognitive Neuroscience (CSCN), School of Psychology, Universidad Adolfo Ibáñez, Santiago, Chile. Ibáñez,A, García,AM Global Brain Health Institute, University of California, San Francisco, United States. García,AM Faculty of Education, National University of Cuyo (UNCuyo), Mendoza, Argentina. García,AM Departamento de Lingüística Y Literatura, Facultad de Humanidades, Universidad de Santiago de Chile, Santiago, Chile., This work was supported by CONICET, FONCYT-PICT 2017-1818, 2017-1820, CONICYT/FONDECYT Regular grant number 1170010, FONDAP grant number 15150012, Programa Interdisciplinario de Investigación Experimental en Comunicación y Cognición (PIIECC), Facultad de Humanidades, USACH, GBHI ALZ UK-20-639295, and the Multi-Partner Consortium to Expand Dementia Research in Latin America (ReDLat), funded by the National Institutes of Aging of the National Institutes of Health under award number R01AG057234, an Alzheimer’s Association grant (SG-20-725707-ReDLat), the Rainwater Foundation, and the Global Brain Health Institute. MJTP has been funded by the Spanish Ministry of Education, Culture and Sport under the FPU program (FPU14/04021) and by a postdoctoral fellowship from the University of Malaga. DLB has been supported by the Juan de la Cierva postdoctoral programme (IJCI-2017-34164) and by I+D+i Project, Andalucia and European Union Funds (FEDER) (UMA18-FEDERJA-221).

Θεματικοί όροι: Diffusion tensor imaging, Gray matter, Brain, Functional neuroimaging, Magnetic resonance imaging, Memory, short-term, Speech, Imagen de difusión tensora, Sustancia gris, Encéfalo, Neuroimagen funcional, Imagen por resonancia magnética, Memoria a corto plazo, Habla, Medical Subject Headings::Persons::Persons::Age Groups::Adult, Medical Subject Headings::Anatomy::Nervous System::Central Nervous System::Brain, Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Neuroimaging::Diffusion Tensor Imaging, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Neuroimaging::Functional Neuroimaging, Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans, Diagnostic and Therapeutic Techniques and Equipment::Diagnosis::Diagnostic Techniques and Procedures::Diagnostic Imaging::Magnetic Resonance Imaging, Medical Subject Headings::Check Tags::Male, Medical Subject Headings::Psychiatry and Psychology::Psychological Phenomena and Processes::Mental Processes::Learning::Memory::Memory, Medical Subject Headings::Persons::Persons::Age Groups::Adult::Middle Aged, Medical Subject Headings::Anatomy::Nervous System::Nerve Net, Medical Subject Headings::Phenomena and Processes::Musculoskeletal and Neural Physiological Phenomena::Nervous System Physiological Phenomena::Nervous System Physiological Processes::Speech

Περιγραφή αρχείου: application/pdf

Relation: https://www.nature.com/articles/s41598-020-67551-z; Torres-Prioris MJ, López-Barroso D, Càmara E, Fittipaldi S, Sedeño L, Ibáñez A, et al. Neurocognitive signatures of phonemic sequencing in expert backward speakers. Sci Rep. 2020 Jun 30;10(1):10621; http://hdl.handle.net/10668/3680; PMC7326922

Διαθεσιμότητα: http://hdl.handle.net/10668/3680
https://doi.org/10.1038/s41598-020-67551-z

Effects of Maternal Fish Oil and/or 5-Methyl-Tetrahydrofolate Supplementation during Pregnancy on Offspring Brain Resting-State at 10 Years Old: A Follow-Up Study from the NUHEAL Randomized Controlled Trial

Συγγραφείς: Azaryah, Hatim, Verdejo-Román, Juan, Martin-Pérez, Cristina, García-Santos, José Antonio, Martínez-Zaldívar, Cristina, Torres-Espínola, Francisco J., Campos, Daniel, Koletzko, Berthold, Pérez-García, Miguel, Catena, Andrés, Campoy, Cristina

Συνεισφορές: Azaryah,H, García-Santos,JA, Martínez-Zaldívar,C, Torres-Espínola,FJ, Campos,D, Campoy,C Department of Paediatrics, School of Medicine, University of Granada, Granada, Spain. Azaryah,H, Campoy,C EURISTIKOS Excellence Centre for Paediatric Research, Biomedical Research Centre, University of Granada, Granada, Spain. Verdejo-Román,J, Martin-Pérez,C, Pérez-García,M, Catena,A Mind, Brain and Behaviour International Research Centre (CIMCYC), University of Granada, Granada, Spain. García-Santos,JA, Campoy,C Instituto de Investigación Biosanitaria de Granada (Ibs-GRANADA), Health Sciences Technological Park, Granada, Spain. Koletzko,B Ludwig-Maximiliams-Universität München, Dr. von Hauner Children’s Hospital, University of Munich Hospitals, Munich, Germany. Campoy,C Spanish Network of Biomedical Research in Epidemiology and Public Health (CIBERESP), Granada’s Node, Institute of Health Carlos III, Madrid, Spain., This work was supported by the Commission of the European Community’s 7th Framework Program (FP7/2008–2013), Grant agreement No. 212652 (NUTRIMENTHE Project), within the 6th Framework Program, Contract no. 007036 (EARNEST Project), and supported in part by the Commission of the European Community within the 5th Framework Program, Contract No. QLK1-CT-1999-00888 (NUHEAL EU Project). This publication is the work of the authors and does not necessarily reflect the views of the Commission of the European Community. The work of B.K. is supported by the European Research Council Advanced Grant ERC-2012-AdG-No.322605 META-GROWTH. J.V.-R is supported by a grant from the Spanish Ministry of Science, Innovation and Universities (FJCI-2017-33396). The funders had no role in the design, analysis or writing of this article.

Θεματικοί όροι: Fish oil, Folate, Pregnancy, Brain function, Resting-state functional neuroimaging, Neurodevelopment, Children, Maternal nutritional physiological phenomena, Aceites de pescado, Ácido fólico, Embarazo, Niño, Fenómenos fisiologicos nutricionales maternos, Medical Subject Headings::Persons::Persons::Age Groups::Adult, Medical Subject Headings::Anatomy::Nervous System::Central Nervous System::Brain, Medical Subject Headings::Persons::Persons::Age Groups::Child, Medical Subject Headings::Phenomena and Processes::Physiological Phenomena::Physiological Processes::Growth and Development::Human Development::Child Development, Medical Subject Headings::Check Tags::Female, Medical Subject Headings::Chemicals and Drugs::Lipids::Oils::Fish Oils, Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Epidemiologic Study Characteristics as Topic::Epidemiologic Studies::Cohort Studies::Longitudinal Studies::Follow-Up Studies, Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans, Diagnostic and Therapeutic Techniques and Equipment::Diagnosis::Diagnostic Techniques and Procedures::Diagnostic Imaging::Magnetic Resonance Imaging, Medical Subject Headings::Check Tags::Male, Medical Subject Headings::Health Care::Environment and Public Health::Public Health::Environmental Pollution::Environmental Exposure::Maternal Exposure, Medical Subject Headings::Phenomena and Processes::Physiological Phenomena::Nutritional Physiological Phenomena::Maternal Nutritional Physiological Phenomena, Medical Subject Headings::Anatomy::Nervous System::Nerve Net, Medical Subject Headings::Phenomena and Processes::Reproductive and Urinary Physiological Phenomena::Reproductive Physiological Phenomena::Reproductive Physiological Processes::Reproduction::Pregnancy, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Statistics as Topic::Principal Component Analysis, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Statistics as Topic::Regression Analysis

Περιγραφή αρχείου: application/pdf

Relation: https://www.mdpi.com/2072-6643/12/9/2701/htm; Azaryah H, Verdejo-Román J, Martin-Pérez C, García-Santos JA, Martínez-Zaldívar C, Torres-Espínola FJ, et al. Effects of Maternal Fish Oil and/or 5-Methyl-Tetrahydrofolate Supplementation during Pregnancy on Offspring Brain Resting-State at 10 Years Old: A Follow-Up Study from the NUHEAL Randomized Controlled Trial. Nutrients. 2020 Sep 4;12(9):2701; http://hdl.handle.net/10668/4058; PMC7551257

Διαθεσιμότητα: http://hdl.handle.net/10668/4058
https://doi.org/10.3390/nu12092701