Artificial Intelligence technologies for assessing skin lesions for referral on the urgent suspected cancer pathway to detect benign lesions and reduce secondary care specialist appointments: early value assessment

Authors: Matthew Walton, Alexis Llewellyn, Eleonora Uphoff, Joseph Lord, Melissa Harden, Robert Hodgson, Mark Simmonds

Source: Health Technology Assessment, Vol 30, Iss 10 (2026)

Subject Terms: skin cancer, melanoma, artificial intelligence, diagnostic testing, systematic review, economic evaluation, Medical technology, R855-855.5

File Description: electronic resource

Relation: https://doaj.org/toc/2046-4924

Access URL: https://doaj.org/article/809aa079b3ac4539b67ddafe8ecf40fe

An Investigation into How Marine Mammal Distribution Is Being Affected by Climate Change, with a Focus on Out of Habitat Marine Mammals, Based on Expert Opinion

Authors: Maia Killian, Laetitia Nunny, Dan Jarvis, Lewis Griffin, Carlos Yaipen-Llanos, Anna Pili, Mark Simmonds

Source: Diversity, Vol 18, Iss 5, p 270 (2026)

Subject Terms: climate change, marine mammals, out of habitat, distribution shift, sea surface temperature, prey distribution, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://www.mdpi.com/1424-2818/18/5/270; https://doaj.org/toc/1424-2818

Access URL: https://doaj.org/article/510936f507804063a4e32b519d276113

Anti-VEGF drugs compared with laser photocoagulation for the treatment of diabetic retinopathy: a systematic review and economic analysis

Authors: Mark Simmonds, Matthew Walton, Rob Hodgson, Alexis Llewellyn, Ruth Walker, Helen Fulbright, Laura Bojke, Lesley Stewart, Sofia Dias, Thomas Rush, John Lawrenson, Tunde Peto, David Steel

Source: Health Technology Assessment, Vol 29, Iss 23 (2025)

Subject Terms: diabetic retinopathy, anti-vegf, panretinal photocoagulation, systematic review, meta-analysis, individual participant data, cost-effectiveness analysis, Medical technology, R855-855.5

File Description: electronic resource

Relation: https://doaj.org/toc/2046-4924

Access URL: https://doaj.org/article/6fbcdb626d7c4a5faf16e4144e0b4726

Anti-VEGF drugs compared with laser photocoagulation for the treatment of proliferative diabetic retinopathy: a systematic review and individual participant data meta-analysis

Authors: Mark Simmonds, Alexis Llewellyn, Ruth Walker, Helen Fulbright, Matthew Walton, Rob Hodgson, Laura Bojke, Lesley Stewart, Sofia Dias, Thomas Rush, João Pereira Figueira, Sobha Sivaprasad, John G Lawrenson, Tunde Peto, David Steel

Source: Health Technology Assessment, Vol 29, Iss 23 (2025)

Subject Terms: diabetic retinopathy, anti-vegf, panretinal photocoagulation, systematic review, meta-analysis, individual participant data, Medical technology, R855-855.5

File Description: electronic resource

Relation: https://doaj.org/toc/2046-4924

Access URL: https://doaj.org/article/f6e8d70524954993bb37e0a06faac9fc

Predictors of treatment REsponse to inhaled corticosteroids (ICS) in Chronic Obstructive pulmonary disease: randomised controlled trials individual participant Data re-Evaluation–protocol of the ICS-RECODE individual participant data meta-analysis

Authors: Matthew Sperrin, John R Hurst, Michael Miligkos, Joergen Vestbo, Pradeesh Sivapalan, Mike Clarke, Lesley Stewart, Jørgen Vestbo, Dave Singh, Tim Felton, Alexander G Mathioudakis, Rebecca Fortescue, Jennifer Quint, Jonathan Marshall, Anurita Majumdar, Jan Hansel, Alice M Turner, Sinduja Manohar, Catherine Fullwood, Nawar Diar Bakerly, Mark Simmonds, Steven Barnes, Ashley Woodcock, Sebastian Bate, Jens-Ulrik Jensen, Markus Fally, Helen Ashdown, Ashley A Woodcock, Emily Howlett, John Linnell, Alan Preston, Glauco Cappellini, Dmitry Galkin, Olaf Joens

Source: BMJ Open, Vol 15, Iss 3 (2025)

Subject Terms: Medicine

File Description: electronic resource

Relation: https://bmjopen.bmj.com/content/15/3/e095541.full; https://doaj.org/toc/2044-6055

Access URL: https://doaj.org/article/fea239c582ac458080c6415ced884e41

A systematic review of the cost-effectiveness of anti-VEGF drugs for the treatment of diabetic retinopathy

Authors: Robert Hodgson, Matthew Walton, Helen Fulbright, Laura Bojke, Ruth Walker, Alexis Llewellyn, Sofia Dias, Lesley Stewart, David Steel, John Lawrenson, Tunde Peto, Mark Simmonds

Source: Health Technology Assessment, Vol 29, Iss 23 (2025)

Subject Terms: cost-effectiveness, diabetic retinopathy, anti-vegf, ranibizumab, Medical technology, R855-855.5

File Description: electronic resource

Relation: https://doaj.org/toc/2046-4924

Access URL: https://doaj.org/article/6bc5050961dd4e538597afb462b1a1ad

Anti-VEGF drugs compared with laser photocoagulation for the treatment of diabetic retinopathy: a systematic review and meta-analysis

Authors: Mark Simmonds, Alexis Llewellyn, Ruth Walker, Helen Fulbright, Matthew Walton, Rob Hodgson, Laura Bojke, Lesley Stewart, Sofia Dias, Thomas Rush, John G Lawrenson, Tunde Peto, David Steel

Source: Health Technology Assessment, Vol 29, Iss 23 (2024)

Subject Terms: diabetic retinopathy, anti-vegf, panretinal photocoagulation, systematic review, meta-analysis, Medical technology, R855-855.5

File Description: electronic resource

Relation: https://doaj.org/toc/2046-4924

Access URL: https://doaj.org/article/fed87cfbb7bd4de1a9c0f7b530ea4bbc

The effectiveness of ablative and non‐surgical therapies for early hepatocellular carcinoma: Systematic review and network meta‐analysis of randomised controlled trials

Authors: Emily South, Ros Wade, Sumayya Anwer, Sahar Sharif‐Hurst, Melissa Harden, Helen Fulbright, Sofia Dias, Mark Simmonds, Ian Rowe, Patricia Thornton, Tze Min Wah, Alison Eastwood

Source: Cancer Medicine, Vol 12, Iss 22, Pp 20759-20772 (2023)

Subject Terms: hepatocellular carcinoma, microwave ablation, network meta‐analysis, percutaneous ethanol injection, radiofrequency ablation, systematic review, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/2045-7634

Access URL: https://doaj.org/article/8a7f91f9400c44a39e45dd83bc436273

Devices for remote continuous monitoring of people with Parkinson’s disease: a systematic review and cost-effectiveness analysis

Authors: Edward Cox, Ros Wade, Robert Hodgson, Helen Fulbright, Thai Han Phung, Nicholas Meader, Simon Walker, Claire Rothery, Mark Simmonds

Source: Health Technology Assessment, Vol 28, Iss 30 (2024)

Subject Terms: parkinson’s disease, remote monitoring, personal kinetigraph, systematic review, economic analysis, Medical technology, R855-855.5

File Description: electronic resource

Relation: https://doaj.org/toc/2046-4924

Access URL: https://doaj.org/article/622770438be64f26883bc4f10dab7464

Estimating interactions in individual participant data meta-analysis: a comparison of methods in practice

Authors: Ruth Walker, Lesley Stewart, Mark Simmonds

Source: Systematic Reviews, Vol 11, Iss 1, Pp 1-9 (2022)

Subject Terms: Individual patient data, Meta-analysis, One-stage, Two-stage, Subgroups, Medicine

File Description: electronic resource

Relation: https://doaj.org/toc/2046-4053

Access URL: https://doaj.org/article/21f5a0d3453449689a163ce121fb1546

Ablative and non-surgical therapies for early and very early hepatocellular carcinoma: a systematic review and network meta-analysis

Authors: Ros Wade, Emily South, Sumayya Anwer, Sahar Sharif-Hurst, Melissa Harden, Helen Fulbright, Robert Hodgson, Sofia Dias, Mark Simmonds, Ian Rowe, Patricia Thornton, Alison Eastwood

Source: Health Technology Assessment, Vol 27, Iss 29 (2023)

Subject Terms: hepatocellular carcinoma, radiofrequency ablation, microwave ablation, percutaneous ethanol injection, systematic review, network meta-analysis, Medical technology, R855-855.5

File Description: electronic resource

Relation: https://doaj.org/toc/1366-5278; https://doaj.org/toc/2046-4924

Access URL: https://doaj.org/article/a07dc13cc387469ea5b424d313ce1bda

EarlyCDT Lung blood test for risk classification of solid pulmonary nodules: systematic review and economic evaluation

Authors: Ana Duarte, Mark Corbett, Hollie Melton, Melissa Harden, Stephen Palmer, Marta Soares, Mark Simmonds

Source: Health Technology Assessment, Vol 26, Iss 49 (2022)

Subject Terms: lung cancer, pulmonary nodules, earlycdt lung, diagnostic accuracy, systematic review, economic analysis, Medical technology, R855-855.5

File Description: electronic resource

Relation: https://doaj.org/toc/1366-5278; https://doaj.org/toc/2046-4924

Access URL: https://doaj.org/article/178448a4bc804fbf8bdc21a336b0092e

Intensive behavioural interventions based on applied behaviour analysis (ABA) for young children with autism: A cost-effectiveness analysis.

Authors: Robert Hodgson, Mousumi Biswas, Stephen Palmer, David Marshall, Mark Rodgers, Lesley Stewart, Mark Simmonds, Dheeraj Rai, Ann Le Couteur

Source: PLoS ONE, Vol 17, Iss 8, p e0270833 (2022)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0270833&type=printable; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/1f7a34754a0e49cdb62877a8d43ed95a

Coenzyme Q10 to manage chronic heart failure with a reduced ejection fraction: a systematic review and economic evaluation

Authors: Lindsay Claxton, Mark Simmonds, Lucy Beresford, Richard Cubbon, Mark Dayer, Stephen S Gottlieb, Nick Hartshorne-Evans, Bruce Kilroy, Alexis Llewellyn, Claire Rothery, Sahar Sharif, Jayne F Tierney, Klaus K Witte, Kath Wright, Lesley A Stewart

Source: Health Technology Assessment, Vol 26, Iss 4 (2022)

Subject Terms: heart failure, coenzyme q10, ubiquinone, micronutrients, vitamins, systematic review, meta-analysis, economic evaluation, value of information analysis, cost–benefit analysis, quality of life, Medical technology, R855-855.5

File Description: electronic resource

Relation: https://doaj.org/toc/1366-5278; https://doaj.org/toc/2046-4924

Access URL: https://doaj.org/article/b151c5176c8c45e09fa4005ddb878ab4

Non-invasive imaging software to assess the functional significance of coronary stenoses: a systematic review and economic evaluation

Authors: Ana Duarte, Alexis Llewellyn, Ruth Walker, Laetitia Schmitt, Kath Wright, Simon Walker, Claire Rothery, Mark Simmonds

Source: Health Technology Assessment, Vol 25, Iss 56 (2021)

Subject Terms: invasive coronary angiography, coronary stenosis, revascularisation, qangio xa 3d/qfr, caas vffr, systematic review, meta-analysis, diagnostic accuracy, cost-effectiveness, Medical technology, R855-855.5

File Description: electronic resource

Relation: https://doaj.org/toc/1366-5278; https://doaj.org/toc/2046-4924

Access URL: https://doaj.org/article/06cac2dc63c543c99e265a69c22fef79

High-throughput, non-invasive prenatal testing for fetal rhesus D status in RhD-negative women: a systematic review and meta-analysis

Authors: Huiqin Yang, Alexis Llewellyn, Ruth Walker, Melissa Harden, Pedro Saramago, Susan Griffin, Mark Simmonds

Source: BMC Medicine, Vol 17, Iss 1, Pp 1-10 (2019)

Subject Terms: Fetal rhesus D status, Non-invasive prenatal testing, Diagnostic accuracy, Anti-D immunoglobulin, Systematic review, Medicine

File Description: electronic resource

Relation: http://link.springer.com/article/10.1186/s12916-019-1254-4; https://doaj.org/toc/1741-7015

Access URL: https://doaj.org/article/ae027a3d771a4fd5bf8eea3924e41579

Evaluating progestogens for prevention of preterm birth international collaborative (EPPPIC) individual participant data (IPD) meta-analysis: protocol

Authors: Lesley A. Stewart, Mark Simmonds, Lelia Duley, Kristina Charlotte Dietz, Melissa Harden, Alex Hodkinson, Alexis Llewellyn, Sahar Sharif, Ruth Walker, Kath Wright, the EPPPIC group

Source: Systematic Reviews, Vol 6, Iss 1, Pp 1-17 (2017)

Subject Terms: Preterm birth, Progestogen, Individual participant data, IPD, Meta-analysis, Medicine

File Description: electronic resource

Relation: http://link.springer.com/article/10.1186/s13643-017-0600-x; https://doaj.org/toc/2046-4053

Access URL: https://doaj.org/article/7bbddba3ede1459ca442cce00e3088a9

Interventions based on early intensive applied behaviour analysis for autistic children: a systematic review and cost-effectiveness analysis

Authors: Mark Rodgers, David Marshall, Mark Simmonds, Ann Le Couteur, Mousumi Biswas, Kath Wright, Dheeraj Rai, Stephen Palmer, Lesley Stewart, Robert Hodgson

Source: Health Technology Assessment, Vol 24, Iss 35 (2020)

Subject Terms: autism, asd, applied behaviour analysis systematic review, ipd, meta-analysis, cost-effectiveness, Medical technology, R855-855.5

File Description: electronic resource

Relation: https://doaj.org/toc/1366-5278; https://doaj.org/toc/2046-4924

Access URL: https://doaj.org/article/3838491c54a6488ea85ea510822c4f5b

Anthropogenic Threats to Wild Cetacean Welfare and a Tool to Inform Policy in This Area

Authors: Christine Nicol, Lars Bejder, Laura Green, Craig Johnson, Linda Keeling, Dawn Noren, Julie Van der Hoop, Mark Simmonds

Source: Frontiers in Veterinary Science, Vol 7 (2020)

Subject Terms: cetacean, animal welfare, anthropogenic threat, expert elicitation, Five Domains model, Veterinary medicine, SF600-1100

File Description: electronic resource

Relation: https://www.frontiersin.org/article/10.3389/fvets.2020.00057/full; https://doaj.org/toc/2297-1769

Access URL: https://doaj.org/article/d77fd755b1fd45a491f2f4bc638bc9ec

Imaging tests for the detection of osteomyelitis: a systematic review

Authors: Alexis Llewellyn, Julie Jones-Diette, Jeannette Kraft, Colin Holton, Melissa Harden, Mark Simmonds

Source: Health Technology Assessment, Vol 23, Iss 61 (2019)

Subject Terms: osteomyelitis, diagnostic accuracy, systematic review, magnetic resonance imaging, positron emission tomography, single photon emission computed tomography, Medical technology, R855-855.5

File Description: electronic resource

Relation: https://doaj.org/toc/1366-5278; https://doaj.org/toc/2046-4924

Access URL: https://doaj.org/article/f28cdf5f5d7045b3b9a2555e6cb2c019