Estimating an adjusted risk difference in a cluster randomized trial with individual-level analyses

Authors: Jules Antoine Pereira Macedo, Bruno Giraudeau, null ESCIENT collaborators

Contributors: Pereira Macedo, Jules Antoine, MethodS in Patients-centered outcomes and HEalth ResEarch (SPHERE), Université de Tours (UT)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Nantes Université - UFR des Sciences Pharmaceutiques et Biologiques (Nantes Univ - UFR Pharmacie), Nantes Université - pôle Santé, Nantes Université (Nantes Univ)-Nantes Université (Nantes Univ)-Nantes Université - pôle Santé, Nantes Université (Nantes Univ)-Nantes Université (Nantes Univ), Centre d’Investigation Clinique Tours CIC 1415 (CIC), Centre Hospitalier Régional Universitaire de Tours (CHRU Tours)-Hôpital Bretonneau-Institut National de la Santé et de la Recherche Médicale (INSERM), ANR-21-CE36-0007,ESCIENT,Edtimation de l'effet d'une intervention complexe sous la forme d'une différence de risques - Challenges conceptuels et biostatistiques(2021)

Source: Statistical Methods in Medical Research. 34:26-44

Subject Terms: g-computation, MESH: Humans, [STAT.ME] Statistics [stat]/Methodology [stat.ME], Statistical, MESH: Cluster Analysis, 01 natural sciences, binary outcome, MESH: Linear Models, generalized estimating equations, risk difference, 03 medical and health sciences, MESH: Randomized Controlled Trials as Topic, 0302 clinical medicine, MESH: Computer Simulation, generalized linear mixed models, MESH: Models, cluster randomized trial, 0101 mathematics, MESH: Normal Distribution, [STAT.ME]Statistics [stat]/Methodology [stat.ME]

File Description: application/pdf

Access URL: https://pubmed.ncbi.nlm.nih.gov/39501723
https://hal.science/hal-04952188v1
https://hal.science/hal-04952188v1/document
https://doi.org/10.1177/09622802241293783

A Systematic Review of Reported Outcomes in Randomized Controlled Trials Targeting Early Interventions in Moderate-to-Severe Traumatic Brain Injury

Authors: Derouin, Yvan, Delhomme, Thomas, Launey, Yoann, Bouras, Marwan, Sautenet, Benedicte, Sébille, Véronique, Cinotti, Raphaël

Contributors: SEBILLE, Veronique, MethodS in Patients-centered outcomes and HEalth ResEarch (SPHERE), Université de Tours (UT)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Nantes Université - UFR des Sciences Pharmaceutiques et Biologiques (Nantes Univ - UFR Pharmacie), Nantes Université - pôle Santé, Nantes Université (Nantes Univ)-Nantes Université (Nantes Univ)-Nantes Université - pôle Santé, Nantes Université (Nantes Univ)-Nantes Université (Nantes Univ), Centre Hospitalier Universitaire de Rennes CHU Rennes = Rennes University Hospital Pontchaillou, Centre de Recherche en Transplantation et Immunologie - Center for Research in Transplantation and Translational Immunology (U1064 Inserm - CR2TI), Institut National de la Santé et de la Recherche Médicale (INSERM)-Nantes Université - UFR de Médecine et des Techniques Médicales (Nantes Univ - UFR MEDECINE), Centre Hospitalier Régional Universitaire de Brest (CHRU Brest), Centre Hospitalier Régional Universitaire CHU Lille (CHRU Lille), Service d'anesthésie et réanimation chirurgicale Nantes, Hôtel-Dieu-Centre Hospitalier Universitaire de Nantes = Nantes University Hospital (CHU Nantes), Centre Hospitalier Universitaire de Nantes = Nantes University Hospital (CHU Nantes)

Source: Journal of Neurotrauma. 41:2238-2247

Subject Terms: Traumatic, post-intensive care syndrome, MESH: Humans, [SDV]Life Sciences [q-bio], traumatic brain injury, core outcome set, Health Care, [SDV] Life Sciences [q-bio], outcome measures, MESH: Randomized Controlled Trials as Topic, Treatment Outcome, Early Medical Intervention, MESH: Brain Injuries, randomized controlled trials, Brain Injuries, Traumatic, Outcome Assessment, Health Care, Humans, MESH: Early Medical Intervention, MESH: Outcome Assessment, MESH: Treatment Outcome, Randomized Controlled Trials as Topic

Access URL: https://pubmed.ncbi.nlm.nih.gov/39013835

Use of Lasers in the Nonsurgical Treatment of Peri-Implantitis: A Systematic Review of the Literature

Authors: Dominique, Claire, Rethoré, Gildas, Verner, Christian, Alliot, Charles, Soueidan, Assem, Struillou, Xavier

Contributors: Regenerative Medicine and Skeleton (RMeS), École nationale vétérinaire, agroalimentaire et de l'alimentation Nantes-Atlantique (ONIRIS)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Nantes Université - UFR Odontologie (Nantes Univ – UFR Odonto), Nantes Université - pôle Santé, Nantes Université (Nantes Univ)-Nantes Université (Nantes Univ)-Nantes Université - pôle Santé, Nantes Université (Nantes Univ)-Nantes Université (Nantes Univ), Nantes Université (Nantes Univ)

Source: Journal of Oral Implantology. 50:552-560

Subject Terms: nonsurgical, MESH: Humans, 0206 medical engineering, review, 02 engineering and technology, Peri-Implantitis, mechanical debridement, 3. Good health, 03 medical and health sciences, MESH: Randomized Controlled Trials as Topic, Treatment Outcome, 0302 clinical medicine, MESH: Laser Therapy, randomized controlled trial, Humans, Laser Therapy, lasers, MESH: Peri-Implantitis, [SDV.MHEP]Life Sciences [q-bio]/Human health and pathology, peri-implantitis, MESH: Treatment Outcome, Randomized Controlled Trials as Topic

Access URL: https://pubmed.ncbi.nlm.nih.gov/38867374

Heterogeneity of outcome measures in depression trials and the relevance of the content of outcome measures to patients: a systematic review: a systematic review

Authors: Veal, C., Tomlinson, A., Cipriani, A., Bulteau, S., Henry, C., Müh, C., Touboul, S., De Waal, N., Levy-Soussan, H., Furukawa, T.A., Fried, E.I., Tran, V.-T., Chevance, A.

Contributors: NantesU M, Dépôt, Centre for Research in Epidemiology and Statistics, Université Sorbonne Paris Cité (USPC)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris Cité (UPCité)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), AP-HP - Hôpital Cochin Broca Hôtel Dieu Paris, Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), University of Oxford, Oxford Health NHS Foundation Trust, Motricité, interactions, performance UR 4334 / Movement - Interactions - Performance (MIP), Le Mans Université (UM)-Nantes Université - UFR des Sciences et Techniques des Activités Physiques et Sportives (Nantes Univ - UFR STAPS), Nantes Université - pôle Santé, Nantes Université (Nantes Univ)-Nantes Université (Nantes Univ)-Nantes Université - pôle Santé, Nantes Université (Nantes Univ)-Nantes Université (Nantes Univ), MethodS in Patients-centered outcomes and HEalth ResEarch (SPHERE), Université de Tours (UT)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Nantes Université - UFR des Sciences Pharmaceutiques et Biologiques (Nantes Univ - UFR Pharmacie), Centre Hospitalier Universitaire de Nantes = Nantes University Hospital (CHU Nantes), Université Paris Cité (UPCité), Groupe hospitalier universitaire Paris psychiatrie & neurosciences Paris (GHU Paris Psychiatrie et Neurosciences), Perception et Mémoire / Perception and Memory, Institut Pasteur Paris (IP)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Cité (UPCité), Collège Doctoral, Sorbonne Université (SU), Auteur indépendant, La Maison Perchée Paris, Kyoto University, Universiteit Leiden = Leiden University, GHU AP-HP Nord - Université Paris Cité, GHU Paris Psychiatrie et Neurosciences

Source: The Lancet Psychiatry. 11:285-294

Subject Terms: Psychiatric Status Rating Scales, MESH: Psychiatric Status Rating Scales, Depressive Disorder, MESH: Humans, [SDV.MHEP] Life Sciences [q-bio]/Human health and pathology, Bipolar Disorder, MESH: Depressive Disorder, Health Care, MESH: Randomized Controlled Trials as Topic, MESH: Bipolar Disorder, Outcome Assessment, Health Care, Humans, MESH: Outcome Assessment, [SDV.MHEP]Life Sciences [q-bio]/Human health and pathology, Randomized Controlled Trials as Topic

File Description: application/pdf

Access URL: https://pubmed.ncbi.nlm.nih.gov/38490761
https://hal.science/hal-04789360v1
https://doi.org/10.1016/s2215-0366(23)00438-8
https://hdl.handle.net/1887/3729697

Lung virome convergence precedes hospital-acquired pneumonia in intubated critically ill patients

Authors: Anani, Hussein, Destras, Grégory, Bulteau, Simon, Castain, Louise, Semanas, Quentin, Burfin, Gwendolyne, Petrier, Mélanie, Martin, Florian, Poulain, Cecile, Dickson, Robert, Bressollette-Bodin, Céline, Roquilly, Antoine, Josset, Laurence

Contributors: Risques Infectieux Tropicaux et Microorganismes Emergents (RITMES), Institut de Recherche pour le Développement (IRD)-Aix Marseille Université (AMU)-Service de Santé des Armées, Hospices Civils de Lyon (HCL), Centre International de Recherche en Infectiologie (CIRI), École normale supérieure de Lyon (ENS de Lyon), Université de Lyon-Université de Lyon-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université Jean Monnet - Saint-Étienne (UJM)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Centre de Recherche en Transplantation et Immunologie - Center for Research in Transplantation and Translational Immunology (U1064 Inserm - CR2TI), Institut National de la Santé et de la Recherche Médicale (INSERM)-Nantes Université - UFR de Médecine et des Techniques Médicales (Nantes Univ - UFR MEDECINE), Nantes Université - pôle Santé, Nantes Université (Nantes Univ)-Nantes Université (Nantes Univ)-Nantes Université - pôle Santé, Nantes Université (Nantes Univ)-Nantes Université (Nantes Univ), Team 1 : Mononuclear phagocytes, Immunopathology, Immunovirology (Team 1 - U1064 Inserm - CR2TI), Nantes Université (Nantes Univ)-Nantes Université (Nantes Univ)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Nantes Université - UFR de Médecine et des Techniques Médicales (Nantes Univ - UFR MEDECINE), Service de virologie CHU Nantes, Centre Hospitalier Universitaire de Nantes = Nantes University Hospital (CHU Nantes), Institut des Agents Infectieux Lyon (IAI), HCL Groupement Hospitalier Nord Lyon, Team 6 : Impact of acute inflammation on host pathogen interactions and lung homeostasis (Team 6 - U1064 Inserm - CR2TI), Centre for Environment, Fisheries and Aquaculture Science Lowestoft (CEFAS), Centre National de Référence des virus respiratoires (dont la grippe et le SARS-CoV2) Lyon (CNR - laboratoire coordonnateur), Hospices Civils de Lyon (HCL)-Hospices Civils de Lyon (HCL), Center for Interdisciplinary Research and Innovation (CIRI), Aristotle University of Thessaloniki

Source: ISSN: 2666-3791 ; Cell Reports Medicine ; https://inserm.hal.science/inserm-05357012 ; Cell Reports Medicine, 2025, 6 (9), pp.102289. ⟨10.1016/j.xcrm.2025.102289⟩.

Subject Terms: Caudoviricetes bacteriophages, Respiratory virome, cross-kingdom interactions, hospital-acquired pneumonia (HAP), intubated critically ill patients, microbiome, respiratory interactome, viral metagenomics, MESH: Aged, MESH: Bacteriophages, MESH: Humans, MESH: Intubation, Intratracheal, MESH: Lung* / microbiology, MESH: Lung* / virology, MESH: Male, MESH: Microbiota, MESH: Middle Aged, MESH: Multicenter Studies as Topic, MESH: Observational Studies as Topic, MESH: Randomized Controlled Trials as Topic, MESH: Clinical Trials, Phase II as Topic, MESH: Streptococcus / virology, MESH: Virome, MESH: Critical Illness, MESH: Cross Infection* / microbiology, MESH: Cross Infection* / virology, MESH: Dysbiosis / microbiology, MESH: Female

Relation: info:eu-repo/semantics/altIdentifier/pmid/40914165; PUBMED: 40914165; PUBMEDCENTRAL: PMC12490257

Availability: https://inserm.hal.science/inserm-05357012
https://inserm.hal.science/inserm-05357012v1/document
https://inserm.hal.science/inserm-05357012v1/file/1-s2.0-S2666379125003623-main.pdf
https://doi.org/10.1016/j.xcrm.2025.102289

Effect of a multimodal analgesia strategy on remifentanil daily consumption in mechanically ventilated adult ICU patients: study protocol for a randomised, placebo-controlled, double-blind, parallel-group clinical trial

Authors: Widehem, Remy, Nicolet, Camille, Delannoy, Violaine, Barthelemi, Laurie, Soulairol, Ian, Lefrant, Jean-Yves, Mura, Thibault, Penetrat-Roger, Claire

Contributors: Centre Hospitalier Régional Universitaire Montpellier (CHRU Montpellier), Institut Charles Gerhardt Montpellier - Institut de Chimie Moléculaire et des Matériaux de Montpellier (ICGM), Institut de Chimie - CNRS Chimie (INC-CNRS)-Centre National de la Recherche Scientifique (CNRS)-Université de Montpellier (UM)-Ecole Nationale Supérieure de Chimie de Montpellier (ENSCM), Université de Montpellier (UM), Centre Hospitalier Universitaire de Nîmes (CHU Nîmes), Initial MAnagement and prevention of acute orGan failures IN critically ill patiEnts (IMAGINE), Institut des Neurosciences de Montpellier (INM), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Montpellier (UM), This clinical study was financially supported by Nîmes University Hospital, Nimes, France (grant number: RIN2022017).

Source: EISSN: 2044-6055 ; BMJ Open ; https://hal.science/hal-05063300 ; BMJ Open, 2025, 15 (1), pp.e090396. ⟨10.1136/bmjopen-2024-090396⟩

Subject Terms: Adult intensive and critical care, INTENSIVE and CRITICAL CARE, PAIN MANAGEMENT, MESH: Humans, MESH: Remifentanil, MESH: Nefopam, MESH: Analgesia, MESH: Female, MESH: Randomized Controlled Trials as Topic, MESH: Feasibility Studies, MESH: Male, MESH: Middle Aged, MESH: Analgesics, MESH: Double-Blind Method, MESH: Respiration, Artificial, Opioid, MESH: Intensive Care Units, MESH: Adult, MESH: Ketamine, MESH: Tramadol, MESH: Pain Management, [SDV]Life Sciences [q-bio]

Relation: info:eu-repo/semantics/altIdentifier/pmid/39832962; PUBMED: 39832962; PUBMEDCENTRAL: PMC11749888

Availability: https://hal.science/hal-05063300
https://hal.science/hal-05063300v1/document
https://hal.science/hal-05063300v1/file/e090396.full.pdf
https://doi.org/10.1136/bmjopen-2024-090396

Assessment of quitting versus using aspirin therapy in patients with stabilized coronary artery disease after stenting who require long-term oral anticoagulation: Rationale for and design of the AQUATIC double-blind randomized trial

Authors: Didier, Romain, Lemesle, Gilles, Montalescot, Gilles, Steg, Philippe Gabriel, Vicaut, Eric, Mottier, Dominique, Bauters, Christophe, Mabo, Philippe, Simon, Tabassome, Bouleti, Claire, Andrieux, Stéphane, Angoulvant, Denis, Vanzetto, Gerald, Kerneis, Mathieu, Cayla, Guillaume, Gilard, Martine

Contributors: Groupe d'Etude de la Thrombose de Bretagne Occidentale (GETBO), Université de Brest (UBO)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Institut Brestois Santé Agro Matière (IBSAM), Université de Brest (UBO)-Université de Brest (UBO), Centre Hospitalier Henri Duffaut (Avignon), Récepteurs Nucléaires, Maladies Métaboliques et Cardiovasculaires - U 1011 (RNMCD), Institut Pasteur de Lille, Pasteur Network (Réseau International des Instituts Pasteur)-Pasteur Network (Réseau International des Instituts Pasteur)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Lille-Centre Hospitalier Régional Universitaire CHU Lille (CHRU Lille), Unité de Recherche sur les Maladies Cardiovasculaires, du Métabolisme et de la Nutrition = Research Unit on Cardiovascular and Metabolic Diseases (ICAN), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Sorbonne Université (SU)-Institut de Cardiométabolisme et Nutrition = Institute of Cardiometabolism and Nutrition CHU Pitié Salpêtrière (IHU ICAN), CHU Pitié-Salpêtrière AP-HP, Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)-CHU Pitié-Salpêtrière AP-HP, Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU), Laboratoire de Recherche Vasculaire Translationnelle (LVTS (UMR_S_1148 / U1148)), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris Cité (UPCité)-Université Sorbonne Paris Nord, Alliance française pour les essais cliniques cardio-vasculaires - French Alliance for Cardiovascular Trials (FACT), Hôpital Lariboisière-Fernand-Widal APHP, Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), CIC Brest, Université de Brest (UBO)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Hôpital de la Cavale Blanche, Centre Hospitalier Régional Universitaire de Brest (CHRU Brest), Biologie Structurale Intégrative (ERL 9002 - INSERM U1167 - BSI), Pasteur Network (Réseau International des Instituts Pasteur)-Pasteur Network (Réseau International des Instituts Pasteur)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Lille-Centre National de la Recherche Scientifique (CNRS), Centre Hospitalier Universitaire Rennes, CIC Poitiers – Centre d'investigation clinique de Poitiers (CIC 1402), Université de Poitiers = University of Poitiers (UP)-Centre hospitalier universitaire de Poitiers = Poitiers University Hospital (CHU de Poitiers La Milétrie )-Direction Générale de l'Organisation des Soins (DGOS)-Institut National de la Santé et de la Recherche Médicale (INSERM), Centre Hospitalier Régional Universitaire de Tours (CHRU Tours), Membrane Signalling and Inflammation in reperfusion Injuries (ISCHEMIA), Université de Tours (UT)-Institut National de la Santé et de la Recherche Médicale (INSERM), Centre Hospitalier Universitaire CHU Grenoble (CHUGA), Centre Hospitalier Universitaire de Nîmes (CHU Nîmes), CHU Montpellier = Montpellier University Hospital, Centre Hospitalier Régional Universitaire Montpellier (CHRU Montpellier), none

Source: ISSN: 1875-2136.

Subject Terms: Chronic coronary syndrome, Stent, Oral anticoagulation, Aspirin, MESH: Administration, Oral, MESH: Anticoagulants* / administration & dosage, MESH: Drug Administration Schedule, MESH: Fibrinolytic Agents* / administration & dosage, MESH: Fibrinolytic Agents* / adverse effects, MESH: Hemorrhage / chemically induced, MESH: Humans, MESH: Multicenter Studies as Topic, MESH: Percutaneous Coronary Intervention* / adverse effects, MESH: Percutaneous Coronary Intervention* / instrumentation, MESH: Percutaneous Coronary Intervention* / mortality, MESH: Platelet Aggregation Inhibitors* / administration & dosage, MESH: Anticoagulants* / adverse effects, MESH: Platelet Aggregation Inhibitors* / adverse effects, MESH: Prospective Studies, MESH: Randomized Controlled Trials as Topic, MESH: Recurrence, MESH: Risk Assessment, MESH: Risk Factors, MESH: Stents, MESH: Time Factors, MESH: Treatment Outcome, MESH: Aspirin* / administration & dosage, MESH: Aspirin* / adverse effects, MESH: Coronary Artery Disease* / diagnosis

Relation: info:eu-repo/semantics/altIdentifier/pmid/40011110; PUBMED: 40011110

Availability: https://hal.science/hal-05109967
https://hal.science/hal-05109967v1/document
https://hal.science/hal-05109967v1/file/Didier%20et%20al.%20-%202025%20-%20Assessment%20of%20quitting%20versus%20using%20aspirin%20therapy%20in%20patients%20with%20stabilized%20coronary%20artery%20dise.pdf
https://doi.org/10.1016/j.acvd.2025.01.006

Randomised controlled trial to assess the impact of hospital–community pharmaceutical care on drug-related problems in oncology practice for at-risk outpatients treated with oral anticancer drugs—a French Society for Oncology Pharmacy (SFPO) study: DROP-SFPO study protocol

Authors: Ranchon, Florence, Huot, Laure, Bardin, Christophe, Madelaine, Isabelle, Cazin, Jean Louis, Pourroy, Bertrand, Tilleul, Patrick, Lemare, François, Rioufol, Catherine

Contributors: Research on Healthcare Performance (RESHAPE - Inserm U1290 - UCBL1), Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Institut National de la Santé et de la Recherche Médicale (INSERM)

Source: ISSN: 2044-6055 ; BMJ Open ; https://hal.science/hal-05223512 ; BMJ Open, 2025, 15 (6), pp.e094825. ⟨10.1136/bmjopen-2024-094825⟩.

Subject Terms: CHEMOTHERAPY, Drug Utilization, Randomized Controlled Trial, MESH: Humans, MESH: Antineoplastic Agents, MESH: Randomized Controlled Trials as Topic, MESH: Pharmacy Service, Hospital, MESH: Community Pharmacy Services, MESH: Drug-Related Side Effects and Adverse Reactions, MESH: Multicenter Studies as Topic, MESH: Medication Errors, MESH: France, MESH: Prospective Studies, MESH: Administration, Oral, MESH: Neoplasms, MESH: Outpatients, [SDV.SPEE]Life Sciences [q-bio]/Santé publique et épidémiologie

Relation: info:eu-repo/semantics/altIdentifier/pmid/40578885; PUBMED: 40578885; PUBMEDCENTRAL: PMC12207170

Availability: https://hal.science/hal-05223512
https://hal.science/hal-05223512v1/document
https://hal.science/hal-05223512v1/file/bmjopen-15-6.pdf
https://doi.org/10.1136/bmjopen-2024-094825

AEROfen: protocol for a phase I, open-label, randomised crossover study evaluating the efficiency of nebulised fentanyl in healthy volunteers – comparing facial versus intranasal administration via pharmacometric modelling

Authors: Follet, Cassandre, Dumont, Audrey, Roussel, Melanie, Gillibert, André, Boedard, Cyprienne, Quillard, Muriel, Ruault, Sophie, Vallin, Florian, Donnadieu, Nathalie, Nunes Ferreira, Davis, Pereira, Tony, Joly, Luc-Marie, Lvovschi, Virginie, Duflot, Thomas

Contributors: Unité de Biostatistiques CHU Rouen, CHU Rouen, Normandie Université (NU)-Normandie Université (NU)-Université de Rouen Normandie (UNIROUEN), Normandie Université (NU), Research on Healthcare Performance (RESHAPE - Inserm U1290 - UCBL1), Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Institut National de la Santé et de la Recherche Médicale (INSERM)

Source: ISSN: 2044-6055 ; BMJ Open ; https://hal.science/hal-05223435 ; BMJ Open, 2025, 15 (7), pp.e091125. ⟨10.1136/bmjopen-2024-091125⟩.

Subject Terms: Clinical Trial, Emergency Departments, Pain management, MESH: Humans, MESH: Fentanyl, MESH: Healthy Volunteers, MESH: Nebulizers and Vaporizers, MESH: Prospective Studies, MESH: Administration, Inhalation, MESH: Clinical Trials, Phase I as Topic, MESH: Adult, MESH: Male, MESH: Female, MESH: Randomized Controlled Trials as Topic, MESH: Young Adult, MESH: Cross-Over Studies, Intranasal, MESH: Analgesics, Opioid, [SDV.SPEE]Life Sciences [q-bio]/Santé publique et épidémiologie

Relation: info:eu-repo/semantics/altIdentifier/pmid/40615143; PUBMED: 40615143; PUBMEDCENTRAL: PMC12226948

Availability: https://hal.science/hal-05223435
https://hal.science/hal-05223435v1/document
https://hal.science/hal-05223435v1/file/bmjopen-15-7.pdf
https://doi.org/10.1136/bmjopen-2024-091125

Oral factor xia inhibitor milvexian after a recent acute coronary syndrome: Rationale and design of the phase 3 (Librexia ACS)

Authors: Gibson, C, Michael, Bahit, M, Cecilia, Mehran, Roxana, Mehta, Shamir, R, Lamee, Rasha, Al, Goto, Shinya, Weitz, Jeffrey, I, Horrow, Jay, Barnathan, Elliot, S, Harrington, Robert, A, Mahaffey, Kenneth, W, Lam, Carolyn, S P, Pieper, Karen, S, Johnston, S, Claiborne, Hankey, Graeme, J, Plotnikov, Alexei, N, Li, Danshi, Deng, Hsiaowei, Steg, Philippe, Gabriel

Contributors: Mécanismes moléculaires dans les démences neurodégénératives (MMDN), École Pratique des Hautes Études (EPHE), Université Paris Sciences et Lettres (PSL)-Université Paris Sciences et Lettres (PSL)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Montpellier (UM), Laboratoire de Recherche Vasculaire Translationnelle (LVTS (UMR_S_1148 / U1148)), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris Cité (UPCité)-Université Sorbonne Paris Nord, This study is sponsored by Bristol Myers Squibb and Janssen Research & Development, LLC., a Johnson & Johnson Company

Source: ISSN: 0002-8703.

Subject Terms: Hemorrhage / chemically induced, inhibitors, Factor XIa* / antagonists &, Acute coronary syndrome, MESH: Acute Coronary Syndrome* / complications, MESH: Acute Coronary Syndrome* / drug therapy, MESH: Myocardial Infarction / prevention & control, MESH: Platelet Aggregation Inhibitors / administration & dosage, MESH: Platelet Aggregation Inhibitors / therapeutic use, MESH: Triazoles, MESH: Randomized Controlled Trials as Topic, MESH: Administration, Oral, MESH: Clinical Trials, Phase III as Topic, MESH: Double-Blind Method, MESH: Factor XIa* / antagonists & inhibitors, MESH: Female, MESH: Hemorrhage / chemically induced, MESH: Humans, MESH: Male, [SDV]Life Sciences [q-bio]

Relation: info:eu-repo/semantics/altIdentifier/pmid/39986336; PUBMED: 39986336

Availability: https://hal.science/hal-05105057
https://hal.science/hal-05105057v1/document
https://hal.science/hal-05105057v1/file/1-s2.0-S0002870325000444-main.pdf
https://doi.org/10.1016/j.ahj.2025.02.011

Safety comparison of single-donor and pooled fecal microbiota transfer product preparation in ulcerative colitis: systematic review and meta-analysis

Authors: Laperrousaz, Bastien, Levast, Benoît, Fontaine, Mathieu, Nancey, Stéphane, Dechelotte, Pierre, Dore, Joel, Lehert, Philippe

Contributors: douville, sabine, MaaT Pharma Lyon, Service d'Hépatologie et de Gastroentérologie Lyon, Hospices Civils de Lyon (HCL), Autophagie infection et immunité - Autophagy Infection Immunity CIRI (CIRI-APY), Centre International de Recherche en Infectiologie (CIRI), École normale supérieure de Lyon (ENS de Lyon), Université de Lyon-Université de Lyon-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université Jean Monnet - Saint-Étienne (UJM)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-École normale supérieure de Lyon (ENS de Lyon), Université de Lyon-Université Jean Monnet - Saint-Étienne (UJM)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Nutrition, Inflammation et axe Microbiote-Intestin-Cerveau (ADEN), Université de Rouen Normandie (UNIROUEN), Normandie Université (NU)-Normandie Université (NU)-Institute for Research and Innovation in Biomedicine (IRIB), Normandie Université (NU)-Normandie Université (NU)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Université de Rouen Normandie (UNIROUEN), Normandie Université (NU)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Institut National de la Santé et de la Recherche Médicale (INSERM), Institute for Research and Innovation in Biomedicine (IRIB), Normandie Université (NU)-Normandie Université (NU)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Normandie Université (NU), Service de Nutrition CHU Rouen, CHU Rouen, Normandie Université (NU)-Normandie Université (NU)-Université de Rouen Normandie (UNIROUEN), Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), MetaGenoPolis (MGP (US 1367)), MICrobiologie de l'ALImentation au Service de la Santé (MICALIS), AgroParisTech-Université Paris-Saclay-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), UCL Crypto Group, Université Catholique de Louvain = Catholic University of Louvain (UCL), University of Melbourne

Source: BMC Gastroenterol
BMC Gastroenterology, Vol 24, Iss 1, Pp 1-12 (2024)

Subject Terms: Pooling, 0301 basic medicine, Benefit-risk, [SDV]Life Sciences [q-bio], Ulcerative, RC799-869, 03 medical and health sciences, MESH: Colitis, MESH: Fecal Microbiota Transplantation, Humans, MESH: Treatment Outcome, Randomized Controlled Trials as Topic, 0303 health sciences, MESH: Humans, Fecal microbiota transfer, Research, Diseases of the digestive system. Gastroenterology, Fecal Microbiota Transplantation, [SDV] Life Sciences [q-bio], Meta-analysis, MESH: Randomized Controlled Trials as Topic, Treatment Outcome, Ulcerative colitis, Colitis, Ulcerative, Safety

Access URL: https://pubmed.ncbi.nlm.nih.gov/39528920
https://doaj.org/article/76d1f1b1578f47ebb1b17441928000b7

Spin and fragility in randomised controlled trials in the anaesthesia literature: a systematic review

Authors: Demarquette, Achille, Perrault, Tristan, Alapetite, Thomas, Bouizegarene, Madjid, Bronnert, Romain, Fouré, Gaël, Masson, Charline, Nicolas, Vivian, Lasocki, Sigismond, Léger, Maxime

Contributors: CCSD, Accord Elsevier, Centre Hospitalier Universitaire d'Angers (CHU Angers), PRES Université Nantes Angers Le Mans (UNAM), MethodS in Patients-centered outcomes and HEalth ResEarch (SPHERE), Université de Tours (UT)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Nantes Université - UFR des Sciences Pharmaceutiques et Biologiques (Nantes Univ - UFR Pharmacie), Nantes Université - pôle Santé, Nantes Université (Nantes Univ)-Nantes Université (Nantes Univ)-Nantes Université - pôle Santé, Nantes Université (Nantes Univ)-Nantes Université (Nantes Univ)

Source: British Journal of Anaesthesia. 130:528-535

Subject Terms: [SDV.MHEP] Life Sciences [q-bio]/Human health and pathology, misleading reporting, fragility index, anaesthesia, MESH: Anesthesia, spin, MESH: Journal Impact Factor, quality of literature, 3. Good health, MESH: Anesthesiology, 03 medical and health sciences, MESH: Randomized Controlled Trials as Topic, 0302 clinical medicine, systematic review, Anesthesiology, Anesthesia, Periodicals as Topic, Journal Impact Factor, reproducibility, [SDV.MHEP]Life Sciences [q-bio]/Human health and pathology, MESH: Periodicals as Topic, Randomized Controlled Trials as Topic

File Description: application/pdf

Access URL: https://pubmed.ncbi.nlm.nih.gov/36759291

Sample Size Calculation for an Individual Stepped‐Wedge Randomized Trial

Authors: Allemang-Trivalle, Aude, Maruani, Annabel, Giraudeau, Bruno

Contributors: Giraudeau, Bruno, MethodS in Patients-centered outcomes and HEalth ResEarch (SPHERE), Université de Tours (UT)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Nantes Université - UFR des Sciences Pharmaceutiques et Biologiques (Nantes Univ - UFR Pharmacie), Nantes Université - pôle Santé, Nantes Université (Nantes Univ)-Nantes Université (Nantes Univ)-Nantes Université - pôle Santé, Nantes Université (Nantes Univ)-Nantes Université (Nantes Univ), Centre d’Investigation Clinique Tours CIC 1415 (CIC), Centre Hospitalier Régional Universitaire de Tours (CHRU Tours)-Hôpital Bretonneau-Institut National de la Santé et de la Recherche Médicale (INSERM)

Source: Biometrical Journal. 66

Subject Terms: MESH: Humans, Biometry, MESH: Monte Carlo Method, Individual stepped-wedge randomized trial, [STAT] Statistics [stat], [STAT]Statistics [stat], Sample size calculation, MESH: Randomized Controlled Trials as Topic, Clinical trials, Individual auto-correlation, Sample Size, Stepped-wedge cluster randomized trial, Humans, MESH: Biometry, Monte Carlo Method, MESH: Sample Size, Randomized Controlled Trials as Topic

File Description: application/pdf

Access URL: https://pubmed.ncbi.nlm.nih.gov/38988194
https://hal.science/hal-04674143v1
https://hal.science/hal-04674143v1/document
https://doi.org/10.1002/bimj.202300167

Association of intravenous thrombolysis and pre-interventional reperfusion: a post hoc analysis of the SWIFT DIRECT trial

Authors: Adnan Mujanovic, Omer Eker, Gaultier Marnat, Daniel Strbian, Petra Ijäs, Cécile Préterre, Aude Triquenot, Jean François Albucher, Maxime Gauberti, David Weisenburger-Lile, Marielle Ernst, Omid Nikoubashman, Anastasios Mpotsaris, Benjamin Gory, Vi Tuan Hua, Marc Ribo, David S Liebeskind, Tomas Dobrocky, Thomas R Meinel, Lukas Buetikofer, Jan Gralla, Urs Fischer, Johannes Kaesmacher

Contributors: Institut Català de la Salut, [Mujanovic A] University Institute of Diagnostic and Interventional Neuroradiology, University Hospital Bern Inselspital, University of Bern, Bern, Switzerland. [Eker O] Department of Neuroradiology, Hospices Civils de Lyon, Bron, France. [Marnat G] Interventional and Diagnostic Neuroradiology, University Hospital Centre Bordeaux, Bordeaux, France. [Strbian D, Ijäs P] Department of Neurology, HUS Helsinki University Hospital, Helsinki, Finland. [Préterre C] Stroke Unit, University Hospital Centre Nantes, Nantes, France. [Ribo M] Unitat d’Ictus, Servei de Neurologia, Vall d’Hebron Hospital Universitari, Barcelona, Spain, Vall d'Hebron Barcelona Hospital Campus, Neurologian yksikkö, HUS Neurocenter, Clinicum, Department of Neurosciences, Mujanovic, Adnan, Eker, Omer, Marnat, Gaultier, Strbian, Daniel, Ijäs, Petra, Préterre, Cécile, Triquenot, Aude, Albucher, Jean François, Gauberti, Maxime, Weisenburger-Lile, David, Kaesmacher, Johannes, Bern University Hospital Berne (Inselspital), Département de Neuroradiologie Centre Hospitalier Lyon Sud - HCL, Centre Hospitalier Lyon Sud CHU - HCL (CHLS), Hospices Civils de Lyon (HCL)-Hospices Civils de Lyon (HCL), Département de Neuro-Radiologie Bordeaux (DNR - Bordeaux), Centre Hospitalier Universitaire de Bordeaux (CHU Bordeaux), Helsinki University Hospital Finland (HUS), Centre Hospitalier Universitaire de Nantes = Nantes University Hospital (CHU Nantes), Service de neurologie Rouen, CHU Rouen, Normandie Université (NU)-Normandie Université (NU)-Université de Rouen Normandie (UNIROUEN), Normandie Université (NU), Départment de Neuroradiologie CHU Caen, Université de Caen Normandie (UNICAEN), Normandie Université (NU)-Normandie Université (NU)-CHU Caen, Normandie Université (NU)-Tumorothèque de Caen Basse-Normandie (TCBN)-Tumorothèque de Caen Basse-Normandie (TCBN), Service de neuroradiologie Suresnes, Hôpital Foch Suresnes, University Medical Center Göttingen (UMG), Universitätsklinikum RWTH Aachen - University Hospital Aachen Aachen, Germany (UKA), RWTH Aachen University = Rheinisch-Westfälische Technische Hochschule Aachen (RWTH Aachen), University-Hospital Munich-Großhadern München, Service de neurologie CHRU Nancy, Centre Hospitalier Régional Universitaire de Nancy (CHRU Nancy), Service de neurologie Reims, Hôpital universitaire Robert Debré Reims (CHU Reims), Vall d'Hebron University Hospital Barcelona, Department of Neurology UCLA, University of California Los Angeles (UCLA), University of California (UC)-University of California (UC)-David Geffen School of Medicine Los Angeles, University of California (UC)-University of California (UC), Universität Bern = University of Bern = Université de Berne (UNIBE), University Hospital Basel Basel

Source: J Neurointerv Surg
Scientia
Scientia. Dipòsit d'Informació Digital del Departament de Salut
instname
Mujanovic, Adnan; Eker, Omer; Marnat, Gaultier; Strbian, Daniel; Ijäs, Petra; Préterre, Cécile; Triquenot, Aude; Albucher, Jean François; Gauberti, Maxime; Weisenburger-Lile, David; Ernst, Marielle; Nikoubashman, Omid; Mpotsaris, Anastasios; Gory, Benjamin; Tuan Hua, Vi; Ribo, Marc; Liebeskind, David S; Dobrocky, Tomas; Meinel, Thomas R; Buetikofer, Lukas; ... (2023). Association of intravenous thrombolysis and pre-interventional reperfusion: a post hoc analysis of the SWIFT DIRECT trial. Journal of neurointerventional surgery, 15(e2), e232-e239. BMJ Publishing Group 10.1136/jnis-2022-019585 <http://dx.doi.org/10.1136/jnis-2022-019585>

Subject Terms: MESH: Thrombolytic Therapy / methods, Mechanical Thrombolysis, [SDV]Life Sciences [q-bio], Surgery, anesthesiology, intensive care, radiology, MESH: Fibrinolytic Agents / therapeutic use, 610 Medicine & health, MESH: Thrombectomy / methods, Brain Ischemia, 03 medical and health sciences, Vasos sanguinis - Cirurgia, 0302 clinical medicine, MESH: Brain Ischemia* / surgery, Fibrinolytic Agents, DISEASES::Nervous System Diseases::Central Nervous System Diseases::Brain Diseases::Cerebrovascular Disorders::Stroke, MESH: Brain Ischemia* / drug therapy, Humans, Thrombolytic Therapy, TÉCNICAS Y EQUIPOS ANALÍTICOS, DIAGNÓSTICOS Y TERAPÉUTICOS::terapéutica::trombólisis mecánica, MESH: Treatment Outcome, Ischemic Stroke, Thrombectomy, Randomized Controlled Trials as Topic, MESH: Humans, Neurosciences, MESH: Mechanical Thrombolysis* / methods, Thrombolysis, MESH: Reperfusion, MESH: Stroke* / diagnostic imaging, 3. Good health, Stroke, MESH: Brain Ischemia* / diagnostic imaging, MESH: Randomized Controlled Trials as Topic, ENFERMEDADES::enfermedades del sistema nervioso::enfermedades del sistema nervioso central::enfermedades cerebrales::trastornos cerebrovasculares::accidente cerebrovascular, Treatment Outcome, MESH: Ischemic Stroke* / etiology, ANALYTICAL, DIAGNOSTIC AND THERAPEUTIC TECHNIQUES, AND EQUIPMENT::Surgical Procedures, Operative::Cardiovascular Surgical Procedures::Vascular Surgical Procedures::Thrombectomy, ANALYTICAL, DIAGNOSTIC AND THERAPEUTIC TECHNIQUES, AND EQUIPMENT::Therapeutics::Mechanical Thrombolysis, Reperfusion, Malalties cerebrovasculars - Cirurgia, TÉCNICAS Y EQUIPOS ANALÍTICOS, DIAGNÓSTICOS Y TERAPÉUTICOS::intervenciones quirúrgicas::procedimientos quirúrgicos cardiovasculares::procedimientos quirúrgicos vasculares::trombectomía, Teràpia trombolítica, MESH: Stroke* / surgery, MESH: Stroke* / drug therapy

File Description: application/pdf

Access URL: https://pubmed.ncbi.nlm.nih.gov/36396433
https://hdl.handle.net/11351/10649
http://hdl.handle.net/10138/572216
https://resolver.sub.uni-goettingen.de/purl?gro-2/118128
https://boris.unibe.ch/174935/

Efficacy of Transcranial Direct Current Stimulation to Improve Insight in Patients With Schizophrenia: A Systematic Review and Meta-analysis of Randomized Controlled Trials

Authors: Ondine Adam, Martin Blay, Andre R Brunoni, Hsin-An Chang, July S Gomes, Daniel C Javitt, Do-Un Jung, Joshua T Kantrowitz, Sanne Koops, Jean-Pierre Lindenmayer, Ulrich Palm, Robert C Smith, Iris E Sommer, Leandro do Costa Lane Valiengo, Thomas W Weickert, Jérôme Brunelin, Marine Mondino

Contributors: Psychiatric Disorders, Neuroscience Research and Clinical Research (CRNL-PSYR2), Centre de recherche en neurosciences de Lyon - Lyon Neuroscience Research Center (CRNL), Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Université Jean Monnet - Saint-Étienne (UJM)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Université Jean Monnet - Saint-Étienne (UJM)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Université de Lyon, Universidade de São Paulo = University of São Paulo (USP), University Medical Center Utrecht (UMCU), Department of Psychiatry and Psychotherapy, Ludwig Maximilian University Munich = Ludwig Maximilians Universität München (LMU), The Florey Institute of Neuroscience and Mental Health, University of Melbourne, University of Groningen Groningen, University of Bergen (UiB), Centre Hospitalier le Vinatier Bron

Source: Schizophrenia Bulletin. 48:1284-1294

Subject Terms: MESH: Humans, Neuromodulation, [SCCO.NEUR]Cognitive science/Neuroscience, MESH: Transcranial Direct Current Stimulation, Psychosis, Transcranial Direct Current Stimulation, Transcranial Magnetic Stimulation, tDCS, MESH: Schizophrenia, 3. Good health, TDCS, 03 medical and health sciences, MESH: Randomized Controlled Trials as Topic, Treatment Outcome, 0302 clinical medicine, MESH: Transcranial Magnetic Stimulation, [SDV.MHEP.PSM]Life Sciences [q-bio]/Human health and pathology/Psychiatrics and mental health, neuromodulation, Schizophrenia, Humans, psychosis, MESH: Treatment Outcome, Randomized Controlled Trials as Topic

Access URL: https://pubmed.ncbi.nlm.nih.gov/35820035

Molecular profiling of non-small-cell lung cancer patients with or without brain metastases included in the randomized SAFIR02-LUNG trial and association with intracranial outcome

Authors: Mogenet, Alice, Barlesi, Fabrice, Besse, Benjamin, Michiels, Stefan, Karimi, Maryam, Tran-Dien, Alicia, Girard, Nicolas, Mazieres, Julien, Audigier-Valette, Clarisse, Locatelli-Sanchez, Myriam, Kamal, Maud, Gestraud, Pierre, Hamza, Abderaouf, Jacquet, Alexandra, Jimenez, Marta, Yara, Sabrina, Greillier, Laurent, Bertucci, François, Planchard, David, Soria, Jean-Charles, Bieche, Ivan, Tomasini, Pascale

Contributors: CCSD, Accord Elsevier, Aix-Marseille Université - École de médecine (AMU SMPM MED), Aix-Marseille Université - Faculté des sciences médicales et paramédicales (AMU SMPM), Aix Marseille Université (AMU)-Aix Marseille Université (AMU), Centre de Recherche en Cancérologie de Marseille (CRCM), Aix Marseille Université (AMU)-Institut Paoli-Calmettes (IPC), Fédération nationale des Centres de lutte contre le Cancer (FNCLCC)-Fédération nationale des Centres de lutte contre le Cancer (FNCLCC)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Institut Gustave Roussy (IGR), Département de médecine oncologique Gustave Roussy, Service de biostatistique et d'épidémiologie (SBE), Direction de la recherche clinique Gustave Roussy, Institut Gustave Roussy (IGR)-Institut Gustave Roussy (IGR), Oncostat (U1018 (Équipe 2)), Institut Gustave Roussy (IGR)-Centre de recherche en épidémiologie et santé des populations (CESP), Université de Versailles Saint-Quentin-en-Yvelines (UVSQ)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpital Paul Brousse-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris-Saclay-Université de Versailles Saint-Quentin-en-Yvelines (UVSQ)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpital Paul Brousse-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris-Saclay, Tarbiat Modares University Tehran, Prédicteurs moléculaires et nouvelles cibles en oncologie (PMNCO), Institut Gustave Roussy (IGR)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris-Saclay, ENGIE GREEN, parent, Service de pneumologie Toulouse, Centre Hospitalier Universitaire de Toulouse (CHU Toulouse), Centre Hospitalier Intercommunal Toulon-La Seyne sur Mer - Hôpital Sainte-Musse, Centre Hospitalier Lyon Sud CHU - HCL (CHLS), Hospices Civils de Lyon (HCL), Institut Curie Paris, Centre de Bioinformatique (CBIO), Mines Paris - PSL (École nationale supérieure des mines de Paris), Université Paris Sciences et Lettres (PSL)-Université Paris Sciences et Lettres (PSL), Imagine - Institut des maladies génétiques (IHU) (Imagine - U1163), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris Cité (UPCité), Centre d'Investigation Clinique en Biotherapie des cancers (CIC 1428 , CBT 507), Institut Gustave Roussy (IGR)-Institut Curie Paris -Institut National de la Santé et de la Recherche Médicale (INSERM), UNICANCER, Méthodes computationnelles pour la prise en charge thérapeutique en oncologie : Optimisation des stratégies par modélisation mécaniste et statistique (COMPO), Inria Sophia Antipolis - Méditerranée (CRISAM), Institut National de Recherche en Informatique et en Automatique (Inria)-Institut National de Recherche en Informatique et en Automatique (Inria)-Centre de Recherche en Cancérologie de Marseille (CRCM), Fédération nationale des Centres de lutte contre le Cancer (FNCLCC)-Fédération nationale des Centres de lutte contre le Cancer (FNCLCC)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Aix Marseille Université (AMU)-Institut Paoli-Calmettes (IPC), Multidisciplinary Oncology and Therapeutic Innovations Unit / Service d’Oncologie Multidisciplinaire et d’Innovations Thérapeutiques (OMIT), Hôpital Nord CHU - APHM

Source: Lung Cancer. 169:31-39

Subject Terms: MESH: Carcinoma, MESH: Mutation, Lung Neoplasms, DNA Copy Number Variations, Molecular biology, [SDV.CAN]Life Sciences [q-bio]/Cancer, [SDV.MHEP.PSR]Life Sciences [q-bio]/Human health and pathology/Pulmonology and respiratory tract, Targeted therapy, 03 medical and health sciences, 0302 clinical medicine, [SDV.CAN] Life Sciences [q-bio]/Cancer, MESH: Tumor Microenvironment, Carcinoma, Non-Small-Cell Lung, Tumor Microenvironment, Humans, MESH: Lung, Non-Small-Cell Lung, Lung, Randomized Controlled Trials as Topic, Comparative Genomic Hybridization, MESH: Humans, Brain Neoplasms, Brain metastases, MESH: Lung Neoplasms, 3. Good health, MESH: Comparative Genomic Hybridization, MESH: Randomized Controlled Trials as Topic, MESH: Brain Neoplasms, Mutation, [SDV.MHEP.PSR] Life Sciences [q-bio]/Human health and pathology/Pulmonology and respiratory tract, MESH: DNA Copy Number Variations, Immunotherapy, Lung cancer

File Description: application/pdf

Access URL: https://pubmed.ncbi.nlm.nih.gov/35609409
https://hal.science/hal-03925563v1/document
https://hal.science/hal-03925563v1
https://doi.org/10.1016/j.lungcan.2022.05.004

Effectiveness of brief interventions in primary care for cannabis users aged from 12 to 25 years old: a systematic review

Authors: Camille Chazal, Charline Roux, Shérazade Kinouani, Matthieu Schuers, Frédéric Fortin, Bruno Pereira, Olivier Blanc, Nathalie Piñol-Domenech, Georges Brousse, Philippe Vorilhon, Catherine Laporte

Contributors: Faculté de Médecine - Clermont-Auvergne (FM - UCA), Université Clermont Auvergne (UCA), Université de Bordeaux (UB), Bordeaux population health (BPH), Université de Bordeaux (UB)-Institut de Santé Publique, d'Épidémiologie et de Développement (ISPED)-Institut National de la Santé et de la Recherche Médicale (INSERM), Université de Rouen Normandie (UNIROUEN), Normandie Université (NU), CHU Rouen, Laboratoire d'Informatique Médicale et Ingénierie des Connaissances en e-Santé (LIMICS), Institut National de la Santé et de la Recherche Médicale (INSERM)-Sorbonne Université (SU)-Université Sorbonne Paris Nord, Institut Pascal (IP), Centre National de la Recherche Scientifique (CNRS)-Université Clermont Auvergne (UCA)-Institut national polytechnique Clermont Auvergne (INP Clermont Auvergne), Université Clermont Auvergne (UCA)-Université Clermont Auvergne (UCA), Service Biostatistiques, Télématiques, Traitement de l’image CHU Clermont-Ferrand, CHU Gabriel Montpied Clermont-Ferrand, CHU Clermont-Ferrand-CHU Clermont-Ferrand-Pôle Santé Publique CHU Clermont-Ferrand, CHU Clermont-Ferrand-CHU Clermont-Ferrand, Bibliothèque Université Clermont Auvergne (BUCA), Service Psychiatrie Adulte CHU Clermont-Ferrand, CHU Clermont-Ferrand-CHU Clermont-Ferrand-Pôle Psychiatrie Enfant-Adulte CHU Clermont-Ferrand, CHU Clermont-Ferrand-CHU Gabriel Montpied Clermont-Ferrand, CHU Clermont-Ferrand, AutomédiCation aCcompagnement Pluriprofessionnel PatienT (ACCePPT)

Source: Family Practice. 39:1156-1168

Subject Terms: Adult, Adolescent, Motivational Interviewing, Adolescents, MESH: Primary Health Care, Young Adult, 03 medical and health sciences, 0302 clinical medicine, General practitioners, MESH: Child, Humans, Emerging adults, Child, MESH: Motivational Interviewing / methods, Cannabis, Randomized Controlled Trials as Topic, MESH: Adolescent, Primary Health Care, Primary care, 3. Good health, MESH: Randomized Controlled Trials as Topic, Crisis Intervention, MESH: Young Adult, MESH: Cannabis, MESH: Crisis Intervention, [SDV.SPEE]Life Sciences [q-bio]/Santé publique et épidémiologie, Brief interventions, 0305 other medical science

Access URL: https://pubmed.ncbi.nlm.nih.gov/35696124

Study protocol for a multicenter randomized controlled trial on simulation-based communication training for pediatric cardiology trainees (SIMUL-CHD)

Authors: Padovani, Paul, Hauet, Quentin, Lefort, Bruno, Chauviré-Drouard, Anne, Letellier, Marine, Bergé, Marie, Marguin, Gaëlle, Titos, Myriam, Grain, Audrey, Babonneau, Marie-Lise, Michon, Claire-Cécile, Trosdorf, Mathilde, Lejus-Bourdeau, Corinne, Lwin, Naychi, Picot, Marie-Christine, Amedro, Pascal, Baruteau, Alban-Elouen

Contributors: Centre Hospitalier Universitaire de Nantes = Nantes University Hospital (CHU Nantes), Département de pédiatrie CHU Nantes, CHU Trousseau Tours, Centre Hospitalier Régional Universitaire de Tours (CHRU Tours), Sans affiliation, Centre de Recherche en Cancérologie et Immunologie Intégrée Nantes-Angers (CRCI2NA), Université d'Angers (UA)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Nantes Université - UFR de Médecine et des Techniques Médicales (Nantes Univ - UFR MEDECINE), Nantes Université - pôle Santé, Nantes Université (Nantes Univ)-Nantes Université (Nantes Univ)-Nantes Université - pôle Santé, Nantes Université (Nantes Univ)-Nantes Université (Nantes Univ), Nantes Université (Nantes Univ), CIC Montpellier, Centre Hospitalier Régional Universitaire Montpellier (CHRU Montpellier)-Hôpital Saint Eloi CHU Montpellier, Centre Hospitalier Régional Universitaire Montpellier (CHRU Montpellier)-Institut National de la Santé et de la Recherche Médicale (INSERM), CHU de Bordeaux Pellegrin Bordeaux, ITX-lab unité de recherche de l'institut du thorax UMR1087 UMR6291 (ITX-lab), Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Nantes Université - UFR de Médecine et des Techniques Médicales (Nantes Univ - UFR MEDECINE), Physiopathologie des Adaptations Nutritionnelles (PhAN), Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)-Nantes Université - UFR de Médecine et des Techniques Médicales (Nantes Univ - UFR MEDECINE), ANR-16-IDEX-0007,NExT (I-SITE),NExT (I-SITE)(2016)

Source: ISSN: 1472-6920 ; BMC Medical Education ; https://nantes-universite.hal.science/hal-05094065 ; BMC Medical Education, 2024, 24 (1), pp.1268. ⟨10.1186/s12909-024-06260-x⟩.

Subject Terms: Pediatric cardiology, Breaking bad news, Communication skills, Congenital heart disease, Empathy, Medical education, Patient-centered care, Simulation-based training, Physician-patient communication, MESH: Child, MESH: Humans, MESH: Heart Defects, Congenital, MESH: Multicenter Studies as Topic, MESH: Pediatrics, MESH: Physician-Patient Relations, MESH: Simulation Training, MESH: Randomized Controlled Trials as Topic, MESH: Cardiology, MESH: Clinical Competence, MESH: Communication, MESH: France, [SDV]Life Sciences [q-bio]

Relation: info:eu-repo/semantics/altIdentifier/pmid/39506730; PUBMED: 39506730; PUBMEDCENTRAL: PMC11539632; WOS: 001349603700003

Availability: https://nantes-universite.hal.science/hal-05094065
https://nantes-universite.hal.science/hal-05094065v1/document
https://nantes-universite.hal.science/hal-05094065v1/file/12909_2024_Article_6260.pdf
https://doi.org/10.1186/s12909-024-06260-x

Vaginal misoprostol versus vaginal dinoprostone for cervical ripening and induction of labour: An individual participant data meta‐analysis of randomised controlled trials

Authors: Patabendige, Malitha, Chan, Fei, Vayssiere, Christophe, Ehlinger, Virginie, van Gemund, Nicolette, Le Cessie, Saskia, Prager, Martina, Marions, Lena, Rozenberg, Patrick, Chevret, Sylvie, Young, David, Le Roux, Paul, Gregson, Sarah, Waterstone, Mark, Rolnik, Daniel, Mol, Ben, Li, Wentao

Contributors: Monash University Clayton, Ministry of Health Colombo, Sri Lanka, Casey Hospital, Berwick, Victoria, Equipe SPHERE (CERPOP), Centre d'Epidémiologie et de Recherche en santé des POPulations (CERPOP), Université Toulouse III - Paul Sabatier (UT3), Communauté d'universités et établissements de Toulouse (Comue de Toulouse)-Communauté d'universités et établissements de Toulouse (Comue de Toulouse)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Toulouse III - Paul Sabatier (UT3), Communauté d'universités et établissements de Toulouse (Comue de Toulouse)-Communauté d'universités et établissements de Toulouse (Comue de Toulouse)-Institut National de la Santé et de la Recherche Médicale (INSERM), Franciscus Hospital, Leiden University Medical Center (LUMC), Universiteit Leiden = Leiden University, Karolinska University Hospital Stockholm, Centre hospitalier intercommunal de Poissy/Saint-Germain-en-Laye - CHIPS Poissy, Service de biostatistique et information médicale de l’hôpital Saint Louis (Equipe ECSTRA) (SBIM), Institut National de la Santé et de la Recherche Médicale (INSERM)-Institut national du cancer (INCa)-Hopital Saint-Louis AP-HP (AP-HP), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Université Paris Cité (UPCité), Dalhousie University Halifax, IWK health centre, University of Cape Town, Queen Elizabeth, The Queen Mother Hospital, Margate, Kent. CT9 4AN, United Kingdom., University of New South Wales Sydney (UNSW)

Source: ISSN: 1470-0328 ; EISSN: 1471-0528.

Subject Terms: induction of labour, IPD, dinoprostone, individual participant data, randomised trials, prostaglandin, misoprostol, meta‐analysis, MESH: Administration, Intravaginal, MESH: Cervical Ripening* / drug effects, MESH: Randomized Controlled Trials as Topic, MESH: Dinoprostone* / administration & dosage, MESH: Female, MESH: Humans, MESH: Labor, Induced* / methods, MESH: Misoprostol* / administration & dosage, MESH: Misoprostol* / adverse effects, MESH: Oxytocics* / administration & dosage, MESH: Pregnancy, [SDV.MHEP.GEO]Life Sciences [q-bio]/Human health and pathology/Gynecology and obstetrics

Availability: https://ut3-toulouseinp.hal.science/hal-04954596
https://ut3-toulouseinp.hal.science/hal-04954596v1/document
https://ut3-toulouseinp.hal.science/hal-04954596v1/file/Patabendige_2024.pdf
https://doi.org/10.1111/1471-0528.17794

How to Balance Prognostic Factors in Controlled Phase II Trials: Stratified Permuted Block Randomization or Minimization? An Analysis of Clinical Trials in Digestive Oncology

Authors: Martin, Elodie, Le Malicot, Karine, Guérin-Charbonnel, Catherine, Bocquet, François, Bouché, Olivier, Turpin, Anthony, Aparicio, Thomas, Legoux, Jean-Louis, Dahan, Laetitia, Taieb, Julien, Lepage, Côme, Dourthe, Louis-Marie, Pétorin, Caroline, Bourgeois, Vincent, Raoul, Jean-Luc, Seegers, Valérie

Contributors: Institut de Cancérologie de l'Ouest Angers/Nantes (UNICANCER/ICO), UNICANCER, Fédération Francophone de Cancérologie Digestive (FFCD), Epidémiologie et recherche clinique en oncologie digestive : EPICAD (CTM UMR 1231) (EPICAD), Center for Translational and Molecular medicine Dijon - UMR1231 (CTM), École Pratique des Hautes Études (EPHE), Université Paris Sciences et Lettres (PSL)-Université Paris Sciences et Lettres (PSL)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Institut Agro Dijon, Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro)-Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro)-Université Bourgogne Europe (UBE)-École Pratique des Hautes Études (EPHE), Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro)-Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro)-Université Bourgogne Europe (UBE), Centre de Recherche en Cancérologie et Immunologie Intégrée Nantes-Angers (CRCI2NA), Université d'Angers (UA)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Nantes Université - UFR de Médecine et des Techniques Médicales (Nantes Univ - UFR MEDECINE), Nantes Université - pôle Santé, Nantes Université (Nantes Univ)-Nantes Université (Nantes Univ)-Nantes Université - pôle Santé, Nantes Université (Nantes Univ)-Nantes Université (Nantes Univ), Droit et changement social (DCS), Centre National de la Recherche Scientifique (CNRS)-Nantes Université - UFR Droit et Sciences Politiques (Nantes Univ - UFR DSP), Nantes Université - pôle Sociétés, Nantes Université (Nantes Univ)-Nantes Université (Nantes Univ)-Nantes Université - pôle Sociétés, Hôpital universitaire Robert Debré Reims (CHU Reims), Service d'oncologie médicale (CHRU Lille), Centre Hospitalier Régional Universitaire CHU Lille (CHRU Lille), Hopital Saint-Louis AP-HP (AP-HP), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Centre Hospitalier Regional d'Orléans (CHRO), Hôpital de la Timone CHU - APHM (TIMONE), Hôpital Européen Georges Pompidou APHP (HEGP), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpitaux Universitaires Paris Ouest - Hôpitaux Universitaires Île de France Ouest (HUPO), Centre de Recherche des Cordeliers (CRC (UMR_S_1138 / U1138)), Université Paris Sciences et Lettres (PSL)-Université Paris Sciences et Lettres (PSL)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Sorbonne Université (SU)-Université Paris Cité (UPCité), CHU Dijon, Centre Hospitalier Universitaire de Dijon - Hôpital François Mitterrand (CHU Dijon), Clinique Sainte Anne Strasbourg, CHU Clermont-Ferrand, Centre Hospitalier Boulogne-sur-mer

Source: ISSN: 1718-7729 ; Current Oncology ; https://nantes-universite.hal.science/hal-05082095 ; Current Oncology, 2024, 31 (6), pp.3513 - 3528. ⟨10.3390/curroncol31060259⟩.

Subject Terms: minimization, phase II trials, randomization, MESH: Humans, MESH: Clinical Trials, Phase II as Topic, MESH: Prognosis, MESH: Randomized Controlled Trials as Topic, MESH: Gastrointestinal Neoplasms, MESH: Research Design, MESH: Digestive System Neoplasms, [SDV]Life Sciences [q-bio]

Relation: info:eu-repo/semantics/altIdentifier/pmid/38920742; PUBMED: 38920742; PUBMEDCENTRAL: PMC11202503

Availability: https://nantes-universite.hal.science/hal-05082095
https://nantes-universite.hal.science/hal-05082095v1/document
https://nantes-universite.hal.science/hal-05082095v1/file/curroncol-31-00259-v3.pdf
https://doi.org/10.3390/curroncol31060259