Ivabradine alleviates the cisplatin-induced cardiotoxicity in rats through regulating the crosstalk between MLCP/PKG, MEK/ERK pathways and miRNA-34a levels.

Authors: Aldabaan NA; Department of Pharmacology, College of Pharmacy, Najran University, Najran, Saudi Arabia., Abdel-Wahab BA; Department of Pharmacology, College of Pharmacy, Najran University, Najran, Saudi Arabia., El-Shoura EAM; Department of Clinical Pharmacy, Faculty of Pharmacy, Al-Azhar University, Assiut, Egypt., Alqahtani SM; Department of Pathology, College of Medicine, The University Hospital, Najran University, Najran, Saudi Arabia., Bakir MB; Department of Medical Education, Faculty of Medicine, Najran University, Najran, Saudi Arabia., Saad HM; Department of Pathology, Faculty of Veterinary Medicine, Matrouh University, Marsa Matruh, Egypt., Mahmoud Omar ZM; Department of Basic Medical Sciences, College of Medicine, Prince Sattam Bin Abdulaziz University, Al-Kharj, Kingdom of Saudi Arabia.; Department of Pharmacology, Faculty of Medicine, Al- Azhar University, Assiut, Egypt., Zaafar D; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Cairo University, Giza, Egypt.

Source: Immunopharmacology and immunotoxicology [Immunopharmacol Immunotoxicol] 2026 Oct; Vol. 48 (5), pp. 857-869. Date of Electronic Publication: 2026 Aug 12.

Publication Type: Journal Article

Journal Info: Publisher: Informa Healthcare Country of Publication: England NLM ID: 8800150 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1532-2513 (Electronic) Linking ISSN: 08923973 NLM ISO Abbreviation: Immunopharmacol Immunotoxicol Subsets: MEDLINE

MeSH Terms: Cisplatin*/toxicity , MicroRNAs*/metabolism , MicroRNAs*/biosynthesis , Ivabradine*/pharmacology , Ivabradine*/therapeutic use , MAP Kinase Signaling System*/drug effects , MAP Kinase Signaling System*/physiology , Cardiotoxicity*/metabolism , Cardiotoxicity*/prevention & control , Cyclic GMP-Dependent Protein Kinases*/metabolism, Oxidative Stress/drug effects ; Animals ; Rats ; Male ; Rats, Sprague-Dawley

MAPK-driven remodeling of mitochondrial dynamics in melanoma: implications for metabolic plasticity and response to targeted therapy.

Authors: Prado-Souza LFL; Center for Natural and Human Sciences, Federal University of ABC, Santo Andre, SP, Brazil. Electronic address: laura.francisca@ufabc.edu.br., Grabauskas LA; Center for Natural and Human Sciences, Federal University of ABC, Santo Andre, SP, Brazil. Electronic address: lorraine.grabauskas@ufabc.edu.br., Chaguri R; Center for Natural and Human Sciences, Federal University of ABC, Santo Andre, SP, Brazil. Electronic address: chaguri.r@ufabc.edu.br., Cardoso CD; Center for Natural and Human Sciences, Federal University of ABC, Santo Andre, SP, Brazil. Electronic address: caroline.damascena@ufabc.edu.br., Urushima FY; Interdisciplinary Center for Biochemistry Investigation, University of Mogi das Cruzes, SP, Brazil. Electronic address: francinyyuko@gmail.com., Mangini LGR; Center for Natural and Human Sciences, Federal University of ABC, Santo Andre, SP, Brazil. Electronic address: luamangini@gmail.com., Ramos VS; Center for Natural and Human Sciences, Federal University of ABC, Santo Andre, SP, Brazil. Electronic address: vyctoria.ramos@ufabc.edu.br., Rodrigues T; Center for Natural and Human Sciences, Federal University of ABC, Santo Andre, SP, Brazil. Electronic address: tiago.rodrigues@ufabc.edu.br.

Source: Biochemical pharmacology [Biochem Pharmacol] 2026 Oct; Vol. 252, pp. 118211. Date of Electronic Publication: 2026 Jul 02.

Publication Type: Journal Article; Review

Journal Info: Publisher: Elsevier Science Country of Publication: England NLM ID: 0101032 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-2968 (Electronic) Linking ISSN: 00062952 NLM ISO Abbreviation: Biochem Pharmacol Subsets: MEDLINE

MeSH Terms: Melanoma*/metabolism , Melanoma*/drug therapy , Melanoma*/pathology , Mitochondrial Dynamics*/drug effects , Mitochondrial Dynamics*/physiology , Mitogen-Activated Protein Kinases*/metabolism , Mitogen-Activated Protein Kinases*/antagonists & inhibitors , Mitogen-Activated Protein Kinases*/genetics , Antineoplastic Agents*/administration & dosage , Skin Neoplasms*/metabolism , Skin Neoplasms*/drug therapy , MAP Kinase Signaling System*/physiology , MAP Kinase Signaling System*/drug effects, Molecular Targeted Therapy/methods ; Mitochondria/metabolism ; Mitochondria/drug effects ; Protein Kinase Inhibitors/administration & dosage ; Humans ; Animals ; Metabolic Reprogramming

Microcolin A, a lipopeptide from marine cyanobacteria, suppresses the non-small cell lung carcinoma by regulating the C-terminal of Hsp90α and ROS/ERK signaling pathways.

Authors: Lu Z; Experimental Training Center of Basic Medical Science, Naval Medical University, Shanghai 200433, China., Wang J; Department of Biochemistry and Molecular Biology, Naval Medical University, Shanghai 200433, China., Li S; Department of Biochemistry and Molecular Biology, Naval Medical University, Shanghai 200433, China., Jiang W; Department of Biochemistry and Molecular Biology, Naval Medical University, Shanghai 200433, China., Zhang X; Department of Biochemistry and Molecular Biology, Naval Medical University, Shanghai 200433, China., Ning Y; Department of Biochemistry and Molecular Biology, Naval Medical University, Shanghai 200433, China., Xu Y; Department of Biochemistry and Molecular Biology, Naval Medical University, Shanghai 200433, China., Jiao B; Department of Biochemistry and Molecular Biology, Naval Medical University, Shanghai 200433, China., Hu B; Naval Medical Center of PLA, Naval Medical University, Shanghai 200433, China., Yu H; Naval Medical Center of PLA, Naval Medical University, Shanghai 200433, China. Electronic address: yuhaobing@smmu.edu.cn., Lu X; Department of Biochemistry and Molecular Biology, Naval Medical University, Shanghai 200433, China. Electronic address: luxiaoling@smmu.edu.cn.

Source: Biochemical pharmacology [Biochem Pharmacol] 2026 Oct; Vol. 252, pp. 118195. Date of Electronic Publication: 2026 Jun 26.

Publication Type: Journal Article

Journal Info: Publisher: Elsevier Science Country of Publication: England NLM ID: 0101032 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-2968 (Electronic) Linking ISSN: 00062952 NLM ISO Abbreviation: Biochem Pharmacol Subsets: MEDLINE

MeSH Terms: Carcinoma, Non-Small-Cell Lung*/metabolism , Carcinoma, Non-Small-Cell Lung*/drug therapy , HSP90 Heat-Shock Proteins*/metabolism , HSP90 Heat-Shock Proteins*/antagonists & inhibitors , Reactive Oxygen Species*/metabolism , Lung Neoplasms*/drug therapy , Lung Neoplasms*/metabolism , MAP Kinase Signaling System*/drug effects , MAP Kinase Signaling System*/physiology , Lipopeptides*/pharmacology , Lipopeptides*/therapeutic use , Lipopeptides*/isolation & purification , Cyanobacteria*/chemistry, Antineoplastic Agents/pharmacology ; Antineoplastic Agents/therapeutic use ; Xenograft Model Antitumor Assays/methods ; Apoptosis/drug effects ; Humans ; Animals ; Mice, Nude ; Cell Line, Tumor ; Mice ; Mice, Inbred BALB C ; Male

Inhibition of the IRE1α/ASK1/JNK signaling pathway ameliorates perioperative neurocognitive disorder in aged mice following abdominal surgery.

Authors: Zhang W; Department of Anesthesiology, Perioperative and Pain Medicine, Nanjing First Hospital, Nanjing Medical University, Nanjing, China., Liu C; Department of Anesthesiology, Perioperative and Pain Medicine, Nanjing First Hospital, Nanjing Medical University, Nanjing, China., Xu R; Department of Anesthesiology, Fuyang People's Hospital, Fuyang, China., Li Z; Department of Anesthesiology, Perioperative and Pain Medicine, Nanjing First Hospital, Nanjing Medical University, Nanjing, China., Xu Y; Department of Anesthesiology, Perioperative and Pain Medicine, Nanjing First Hospital, Nanjing Medical University, Nanjing, China., Yin J; Department of Anesthesiology, Perioperative and Pain Medicine, Nanjing First Hospital, Nanjing Medical University, Nanjing, China., Han F; Department of Surgery, Lianshui County People's Hospital, Huai'an, China., Meng Q; School of Medicine, Nanjing University of Chinese Medicine, Nanjing, China., Duan M; Department of Anesthesiology, Nanjing Tianyinshan Hospital, The First Affiliated Hospital of China Pharmaceutical University, Nanjing, China; Department of Anesthesiology, Nanjing BenQ Medical Center, The Affiliated BenQ Hospital of Nanjing Medical University, Nanjing, China. Electronic address: dml9001@nju.edu.cn., Zhang Z; School of Basic Medical Sciences, Nanjing Medical University, Nanjing, China.. Electronic address: zzy@njmu.edu.cn., Wang X; Department of Anesthesiology, Perioperative and Pain Medicine, Nanjing First Hospital, Nanjing Medical University, Nanjing, China. Electronic address: wxl145381@njmu.edu.cn.

Source: Brain research [Brain Res] 2026 Oct 01; Vol. 1888, pp. 150397. Date of Electronic Publication: 2026 Jun 01.

Publication Type: Journal Article

Journal Info: Publisher: Elsevier/North-Holland Biomedical Press Country of Publication: Netherlands NLM ID: 0045503 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1872-6240 (Electronic) Linking ISSN: 00068993 NLM ISO Abbreviation: Brain Res Subsets: MEDLINE

MeSH Terms: Endoribonucleases*/metabolism , Endoribonucleases*/antagonists & inhibitors , Protein Serine-Threonine Kinases*/metabolism , Protein Serine-Threonine Kinases*/antagonists & inhibitors , MAP Kinase Kinase Kinase 5*/metabolism , MAP Kinase Signaling System*/drug effects , MAP Kinase Signaling System*/physiology , Neurocognitive Disorders*/metabolism , Neurocognitive Disorders*/etiology , Postoperative Cognitive Complications*/metabolism, Endoplasmic Reticulum Stress/physiology ; Endoplasmic Reticulum Stress/drug effects ; Hippocampus/metabolism ; Abdomen/surgery ; Aging/metabolism ; Animals ; Mice ; Male ; Mice, Inbred C57BL ; Signal Transduction ; Disease Models, Animal

Advances in MAPK pathway-targeted therapy for ameloblastoma: A literature review.

Authors: Lv Y; Department of Oral and Maxillofacial Surgery, Shandong University & Shandong Key Laboratory of Oral Tissue Regeneration & Shandong Engineering Research Center of Dental Materials and Oral Tissue Regeneration & Shandong Provincial Clinical Research Center for Oral Diseases, School and Hospital of Stomatology, Cheeloo College of Medicine, China., Yang Z; Department of Oral and Maxillofacial Surgery, Shandong University & Shandong Key Laboratory of Oral Tissue Regeneration & Shandong Engineering Research Center of Dental Materials and Oral Tissue Regeneration & Shandong Provincial Clinical Research Center for Oral Diseases, School and Hospital of Stomatology, Cheeloo College of Medicine, China., Pan Z; Department of Oral and Maxillofacial Surgery, Shandong University & Shandong Key Laboratory of Oral Tissue Regeneration & Shandong Engineering Research Center of Dental Materials and Oral Tissue Regeneration & Shandong Provincial Clinical Research Center for Oral Diseases, School and Hospital of Stomatology, Cheeloo College of Medicine, China., Liu X; Department of Oral and Maxillofacial Surgery, Shandong University & Shandong Key Laboratory of Oral Tissue Regeneration & Shandong Engineering Research Center of Dental Materials and Oral Tissue Regeneration & Shandong Provincial Clinical Research Center for Oral Diseases, School and Hospital of Stomatology, Cheeloo College of Medicine, China., Yu J; Department of Oral and Maxillofacial Surgery, Shandong University & Shandong Key Laboratory of Oral Tissue Regeneration & Shandong Engineering Research Center of Dental Materials and Oral Tissue Regeneration & Shandong Provincial Clinical Research Center for Oral Diseases, School and Hospital of Stomatology, Cheeloo College of Medicine, China., Li B; Department of Social Medicine and Health Management, School of Public Health, Cheeloo College of Medicine, Shandong University, China; NHC Key Lab of Health Economics and Policy Research (Shandong University), China; Center for Health Management and Policy Research, Shandong University (Shandong Provincial Key New Think Tank), China., Zhang F; Department of Oral and Maxillofacial Surgery, Shandong University & Shandong Key Laboratory of Oral Tissue Regeneration & Shandong Engineering Research Center of Dental Materials and Oral Tissue Regeneration & Shandong Provincial Clinical Research Center for Oral Diseases, School and Hospital of Stomatology, Cheeloo College of Medicine, China. Electronic address: zfengh@sdu.edu.cn.

Source: Journal of stomatology, oral and maxillofacial surgery [J Stomatol Oral Maxillofac Surg] 2026 Oct; Vol. 127 (5), pp. 102829. Date of Electronic Publication: 2026 May 13.

Publication Type: Journal Article; Review

Journal Info: Publisher: Elsevier Masson SAS Country of Publication: France NLM ID: 101701089 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2468-7855 (Electronic) Linking ISSN: 24687855 NLM ISO Abbreviation: J Stomatol Oral Maxillofac Surg Subsets: MEDLINE

MeSH Terms: Ameloblastoma*/genetics , Ameloblastoma*/drug therapy , Ameloblastoma*/therapy , Molecular Targeted Therapy*/methods , MAP Kinase Signaling System*/drug effects , MAP Kinase Signaling System*/genetics , Jaw Neoplasms*/genetics , Jaw Neoplasms*/drug therapy, Proto-Oncogene Proteins B-raf/genetics ; Proto-Oncogene Proteins B-raf/antagonists & inhibitors ; Protein Kinase Inhibitors/therapeutic use ; Humans ; Mutation ; Prognosis

Single-Molecule Imaging Reveals ERK-Dependent Spatial Translation in Cardiomyocytes.

Authors: Erlich I; The Rappaport Family Institute for Research in the Medical Sciences and the Ruth and Bruce Rappaport Faculty of Medicine, Department of Physiology, Biophysics, and Systems Biology, Technion-Israel Institute of Technology, Haifa, Israel (I.E., G.D., R.H., I.K.)., Douvdevany G; The Rappaport Family Institute for Research in the Medical Sciences and the Ruth and Bruce Rappaport Faculty of Medicine, Department of Physiology, Biophysics, and Systems Biology, Technion-Israel Institute of Technology, Haifa, Israel (I.E., G.D., R.H., I.K.)., Haddad R; The Rappaport Family Institute for Research in the Medical Sciences and the Ruth and Bruce Rappaport Faculty of Medicine, Department of Physiology, Biophysics, and Systems Biology, Technion-Israel Institute of Technology, Haifa, Israel (I.E., G.D., R.H., I.K.)., Prosser BL; Department of Physiology, Pennsylvania Muscle Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia (B.L.P.)., Kehat I; The Rappaport Family Institute for Research in the Medical Sciences and the Ruth and Bruce Rappaport Faculty of Medicine, Department of Physiology, Biophysics, and Systems Biology, Technion-Israel Institute of Technology, Haifa, Israel (I.E., G.D., R.H., I.K.).

Source: Circulation research [Circ Res] 2026 Sep 25; Vol. 139 (8), pp. e329033. Date of Electronic Publication: 2026 Aug 21.

Publication Type: Journal Article

Journal Info: Publisher: Lippincott Williams & Wilkins Country of Publication: United States NLM ID: 0047103 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1524-4571 (Electronic) Linking ISSN: 00097330 NLM ISO Abbreviation: Circ Res Subsets: MEDLINE

MeSH Terms: Myocytes, Cardiac*/drug effects , Myocytes, Cardiac*/enzymology , Myocytes, Cardiac*/metabolism , Protein Biosynthesis*/drug effects , Protein Biosynthesis*/physiology , Extracellular Signal-Regulated MAP Kinases*/metabolism , MAP Kinase Signaling System*/physiology , MAP Kinase Signaling System*/drug effects , Single Molecule Imaging*/methods, Microtubules/metabolism ; Animals ; Rats ; Rats, Sprague-Dawley ; Cells, Cultured ; Male

Ginsenoside RD2 inhibits gastric cancer progression by suppressing TRIM46-mediated DUSP1 ubiquitination and modulating the ERK signaling pathway.

Authors: Jiang J; Endoscopy Center, Minhang Hospital, Fudan University, No.170 Xinsong Road, Shanghai, 201199, China., Tang J; Endoscopy Center, Minhang Hospital, Fudan University, No.170 Xinsong Road, Shanghai, 201199, China., Li D; Endoscopy Center, Minhang Hospital, Fudan University, No.170 Xinsong Road, Shanghai, 201199, China., Qin Z; Endoscopy Center, Minhang Hospital, Fudan University, No.170 Xinsong Road, Shanghai, 201199, China., Li F; Endoscopy Center, Minhang Hospital, Fudan University, No.170 Xinsong Road, Shanghai, 201199, China., Bei S; Endoscopy Center, Minhang Hospital, Fudan University, No.170 Xinsong Road, Shanghai, 201199, China., Zhang X; Endoscopy Center, Minhang Hospital, Fudan University, No.170 Xinsong Road, Shanghai, 201199, China. Electronic address: zxh_njzx@163.com., Li H; Endoscopy Center, Minhang Hospital, Fudan University, No.170 Xinsong Road, Shanghai, 201199, China. Electronic address: 176545456@qq.com., Feng L; Endoscopy Center, Minhang Hospital, Fudan University, No.170 Xinsong Road, Shanghai, 201199, China. Electronic address: feng_li@fudan.edu.cn.

Source: Journal of pharmacological sciences [J Pharmacol Sci] 2026 Sep; Vol. 162 (1), pp. 11-28. Date of Electronic Publication: 2026 Jun 02.

Publication Type: Journal Article

Journal Info: Publisher: Japanese Pharmacological Society Country of Publication: Japan NLM ID: 101167001 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1347-8648 (Electronic) Linking ISSN: 13478613 NLM ISO Abbreviation: J Pharmacol Sci Subsets: MEDLINE

MeSH Terms: Stomach Neoplasms*/pathology , Stomach Neoplasms*/genetics , Stomach Neoplasms*/drug therapy , Dual Specificity Phosphatase 1*/metabolism , Dual Specificity Phosphatase 1*/genetics , MAP Kinase Signaling System*/drug effects , MAP Kinase Signaling System*/genetics , Ginsenosides*/pharmacology , Ginsenosides*/therapeutic use , Ubiquitination*/drug effects , Ubiquitination*/genetics , Tripartite Motif Proteins*/metabolism , Phytotherapy*, Epithelial-Mesenchymal Transition/drug effects ; Epithelial-Mesenchymal Transition/genetics ; Cell Proliferation/drug effects ; Cell Proliferation/genetics ; Cell Movement/drug effects ; Gene Expression/drug effects ; Humans ; Cell Line, Tumor ; Disease Progression ; Animals ; Dose-Response Relationship, Drug

Pyrethrin II impairs mitochondrial potential through ROS and MAPK pathways in HT‑22 cells.

Authors: Gao J; Department of Biological and Food Engineering, Lyuliang University, Lvliang, Shanxi 033001, China., Zhang X; Department of Biochemistry and Molecular Biology, Shanxi Medical University, Taiyuan, Shanxi 030001, China., Mu Q; Department of Biochemistry and Molecular Biology, Shanxi Medical University, Taiyuan, Shanxi 030001, China., Liu Y; Department of Biochemistry and Molecular Biology, Shanxi Medical University, Taiyuan, Shanxi 030001, China., Yang H; Department of Hepatobiliary Surgery, The First Hospital of Shanxi Medical University, Taiyuan, Shanxi 030001, China., Cao R; Department of Biochemistry and Molecular Biology, Shanxi Medical University, Taiyuan, Shanxi 030001, China., Wang X; Beijing Municipal Key Laboratory of Child Development and Nutriomics, Capital Institute of Pediatrics, Beijing 100020, China., Yu B; Department of Biochemistry and Molecular Biology, Shanxi Medical University, Taiyuan, Shanxi 030001, China. Electronic address: shanxiyangcheng@126.com., Zhang L; Department of Biochemistry and Molecular Biology, Shanxi Medical University, Taiyuan, Shanxi 030001, China; Department of Hepatobiliary Surgery, The First Hospital of Shanxi Medical University, Taiyuan, Shanxi 030001, China. Electronic address: zhangli3788@163.com., Guo Y; Department of Pain Management, Shanxi Bethune Hospital, Shanxi Academy of Medical Sciences, Third Hospital of Shanxi Medical University, Tongji Shanxi Hospital, Taiyuan 030032, China. Electronic address: guoyaoyao@sxbqeh.com.cn.

Source: Neurotoxicology [Neurotoxicology] 2026 Sep; Vol. 116, pp. 103518. Date of Electronic Publication: 2026 Jul 13.

Publication Type: Journal Article

Journal Info: Publisher: Elsevier Science Country of Publication: Netherlands NLM ID: 7905589 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1872-9711 (Electronic) Linking ISSN: 0161813X NLM ISO Abbreviation: Neurotoxicology Subsets: MEDLINE

MeSH Terms: Reactive Oxygen Species*/metabolism , Membrane Potential, Mitochondrial*/drug effects , Pyrethrins*/toxicity , MAP Kinase Signaling System*/drug effects , MAP Kinase Signaling System*/physiology , Insecticides*/toxicity , Neurons*/drug effects , Neurons*/metabolism, Apoptosis/drug effects ; Cell Survival/drug effects ; Cell Proliferation/drug effects ; Mitochondria/drug effects ; Animals ; Cell Line ; Mice ; Dose-Response Relationship, Drug

Pharmacological inhibition of Htr2b ameliorates bone destruction in glucocorticoid-induced osteonecrosis of the femoral head by suppressing Ca²⁺/ERK ‑ dependent osteoclast hyperactivation.

Authors: Yuan T; Department of Joint Surgery, Shandong Provincial Hospital, Cheeloo College of Medicine, Shandong University, Jinan, Shandong 250012, China., Wang Y; Department of Joint Surgery, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, Shandong 250021, China; Skeletal Aging Research Laboratory, Medical Science and Technology Innovation Center, Shandong First Medical University & Shandong Academy of Medical Sciences, Jinan, Shandong 250117, China., Qin C; Department of Joint Surgery, Shandong Provincial Hospital, Cheeloo College of Medicine, Shandong University, Jinan, Shandong 250012, China., Qian K; Department of Joint Surgery, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, Shandong 250021, China; Skeletal Aging Research Laboratory, Medical Science and Technology Innovation Center, Shandong First Medical University & Shandong Academy of Medical Sciences, Jinan, Shandong 250117, China., Lv Y; Department of Joint Surgery, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, Shandong 250021, China; Skeletal Aging Research Laboratory, Medical Science and Technology Innovation Center, Shandong First Medical University & Shandong Academy of Medical Sciences, Jinan, Shandong 250117, China., Wang W; Department of Joint Surgery, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, Shandong 250021, China; Skeletal Aging Research Laboratory, Medical Science and Technology Innovation Center, Shandong First Medical University & Shandong Academy of Medical Sciences, Jinan, Shandong 250117, China., Li Z; Department of Joint Surgery, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, Shandong 250021, China; Skeletal Aging Research Laboratory, Medical Science and Technology Innovation Center, Shandong First Medical University & Shandong Academy of Medical Sciences, Jinan, Shandong 250117, China. Electronic address: liziqing@sdfmu.edu.cn., Sun S; Department of Joint Surgery, Shandong Provincial Hospital, Cheeloo College of Medicine, Shandong University, Jinan, Shandong 250012, China; Department of Joint Surgery, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, Shandong 250021, China; Skeletal Aging Research Laboratory, Medical Science and Technology Innovation Center, Shandong First Medical University & Shandong Academy of Medical Sciences, Jinan, Shandong 250117, China. Electronic address: sunshui@sdfmu.edu.cn.

Source: Biochemical pharmacology [Biochem Pharmacol] 2026 Sep; Vol. 251 (Pt 1), pp. 118120. Date of Electronic Publication: 2026 Jun 03.

Publication Type: Journal Article

Journal Info: Publisher: Elsevier Science Country of Publication: England NLM ID: 0101032 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-2968 (Electronic) Linking ISSN: 00062952 NLM ISO Abbreviation: Biochem Pharmacol Subsets: MEDLINE

MeSH Terms: Osteoclasts*/drug effects , Osteoclasts*/metabolism , Receptor, Serotonin, 5-HT2B*/metabolism , Receptor, Serotonin, 5-HT2B*/genetics , Glucocorticoids*/toxicity , Serotonin 5-HT2 Receptor Antagonists*/pharmacology , Serotonin 5-HT2 Receptor Antagonists*/therapeutic use , Femur Head Necrosis*/chemically induced , Femur Head Necrosis*/metabolism , Femur Head Necrosis*/drug therapy , Femur Head Necrosis*/pathology , Calcium*/metabolism , MAP Kinase Signaling System*/drug effects , MAP Kinase Signaling System*/physiology, Dexamethasone/toxicity ; Femur Head/drug effects ; Femur Head/metabolism ; Femur Head/pathology ; Animals ; Mice, Inbred C57BL ; Mice ; Male

Naringin affects VEGFC/TGF-β1 to mediate intercellular communication in MASH through coordinated Src and p38 MAPK pathways.

Authors: Li J; The First Affiliated Hospital of Zhejiang Chinese Medical University (Zhejiang Provincial Hospital of Chinese Medicine), Hangzhou 310006, People's Republic of China., Nie A; The First Affiliated Hospital of Zhejiang Chinese Medical University (Zhejiang Provincial Hospital of Chinese Medicine), Hangzhou 310006, People's Republic of China; School of Basic Medical Sciences, Zhejiang Chinese Medical University, Hangzhou 310053, People's Republic of China., Mao F; The Key Laboratory of Developmental Genes and Human Disease, School of Life Science and Technology, Southeast University, Nanjing 210096, People's Republic of China., Chen Z; The First Affiliated Hospital of Zhejiang Chinese Medical University (Zhejiang Provincial Hospital of Chinese Medicine), Hangzhou 310006, People's Republic of China., Kang H; The First Affiliated Hospital of Zhejiang Chinese Medical University (Zhejiang Provincial Hospital of Chinese Medicine), Hangzhou 310006, People's Republic of China., Yao K; The First Affiliated Hospital of Zhejiang Chinese Medical University (Zhejiang Provincial Hospital of Chinese Medicine), Hangzhou 310006, People's Republic of China., Chen Z; The First Affiliated Hospital of Zhejiang Chinese Medical University (Zhejiang Provincial Hospital of Chinese Medicine), Hangzhou 310006, People's Republic of China. Electronic address: zhiych123@163.com., Hong W; The First Affiliated Hospital of Zhejiang Chinese Medical University (Zhejiang Provincial Hospital of Chinese Medicine), Hangzhou 310006, People's Republic of China; School of Basic Medical Sciences, Zhejiang Chinese Medical University, Hangzhou 310053, People's Republic of China. Electronic address: hongweibio@pku.edu.cn.

Source: Biochemical pharmacology [Biochem Pharmacol] 2026 Sep; Vol. 251 (Pt 1), pp. 118009. Date of Electronic Publication: 2026 Apr 25.

Publication Type: Journal Article

Journal Info: Publisher: Elsevier Science Country of Publication: England NLM ID: 0101032 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-2968 (Electronic) Linking ISSN: 00062952 NLM ISO Abbreviation: Biochem Pharmacol Subsets: MEDLINE

MeSH Terms: Transforming Growth Factor beta1*/metabolism , p38 Mitogen-Activated Protein Kinases*/metabolism , Flavanones*/pharmacology , Flavanones*/therapeutic use , Vascular Endothelial Growth Factor C*/metabolism , Vascular Endothelial Growth Factor C*/genetics , Fatty Liver*/metabolism , Fatty Liver*/drug therapy , src-Family Kinases*/metabolism , MAP Kinase Signaling System*/drug effects , MAP Kinase Signaling System*/physiology, Animals ; Mice ; Male ; Mice, Inbred C57BL

Molecular crosstalk between MAPK signaling and neuroprotective pathways in Parkinson's disease: from pathogenesis to therapeutic potential.

Authors: Shalabi MG; Department of Clinical Laboratory Sciences, College of Applied Medical Sciences, Jouf University, Sakala 72388, Saudi Arabia. Electronic address: mgshalbi@ju.edu.sa., Al-Kuraishy HM; Department of Clinical Pharmacology and Medicine, College of Medicine, Mustansiriyah University, Baghdad, Iraq. Electronic address: haydermutter@uomustansiriyah.edu.iq., Shokr MM; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Sinai University- Arish Branch, Arish 45511, Egypt. Electronic address: mostafa.mohsen@su.edu.eg., Batiha GE; Department of Pharmacology and Therapeutics, Faculty of Veterinary Medicine, Damanhour University, Damanhour 22511, AlBeheira, Egypt. Electronic address: Gaberelsaberbatiha@gmail.com.

Source: Neuroscience [Neuroscience] 2026 Aug 28; Vol. 610, pp. 297-310. Date of Electronic Publication: 2026 Jun 19.

Publication Type: Journal Article; Review

Journal Info: Publisher: Elsevier Science Country of Publication: United States NLM ID: 7605074 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-7544 (Electronic) Linking ISSN: 03064522 NLM ISO Abbreviation: Neuroscience Subsets: MEDLINE

MeSH Terms: Parkinson Disease*/metabolism , Parkinson Disease*/drug therapy , MAP Kinase Signaling System*/physiology , MAP Kinase Signaling System*/drug effects , Neuroprotection*/physiology , Mitogen-Activated Protein Kinases*/metabolism, Neuroprotective Agents/pharmacology ; Neuroprotective Agents/therapeutic use ; Dopaminergic Neurons/metabolism ; Humans ; Animals

Toxic effects of 5-hydroxymethylfurfural on intestinal epithelial cell and its impact on the expression of MAPK pathway-related genes.

Authors: Qin D; Scientific Research Base of Tea Comprehensive Utilization Technology Integration of Ministry of Agriculture and Rural Affairs, Guangdong Provincial Key Laboratory of Food Quality and Safety, College of Food Science, South China Agricultural University, Guangzhou 510642, China., Chen X; Scientific Research Base of Tea Comprehensive Utilization Technology Integration of Ministry of Agriculture and Rural Affairs, Guangdong Provincial Key Laboratory of Food Quality and Safety, College of Food Science, South China Agricultural University, Guangzhou 510642, China., Pan K; Scientific Research Base of Tea Comprehensive Utilization Technology Integration of Ministry of Agriculture and Rural Affairs, Guangdong Provincial Key Laboratory of Food Quality and Safety, College of Food Science, South China Agricultural University, Guangzhou 510642, China., Tang Z; Scientific Research Base of Tea Comprehensive Utilization Technology Integration of Ministry of Agriculture and Rural Affairs, Guangdong Provincial Key Laboratory of Food Quality and Safety, College of Food Science, South China Agricultural University, Guangzhou 510642, China., Chen Z; Scientific Research Base of Tea Comprehensive Utilization Technology Integration of Ministry of Agriculture and Rural Affairs, Guangdong Provincial Key Laboratory of Food Quality and Safety, College of Food Science, South China Agricultural University, Guangzhou 510642, China., Lin X; Scientific Research Base of Tea Comprehensive Utilization Technology Integration of Ministry of Agriculture and Rural Affairs, Guangdong Provincial Key Laboratory of Food Quality and Safety, College of Food Science, South China Agricultural University, Guangzhou 510642, China., Zhang Y; Scientific Research Base of Tea Comprehensive Utilization Technology Integration of Ministry of Agriculture and Rural Affairs, Guangdong Provincial Key Laboratory of Food Quality and Safety, College of Food Science, South China Agricultural University, Guangzhou 510642, China. Electronic address: zhangyy@scau.edu.cn.

Source: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association [Food Chem Toxicol] 2026 Aug; Vol. 214, pp. 116112. Date of Electronic Publication: 2026 Apr 24.

Publication Type: Journal Article

Journal Info: Publisher: Elsevier Science Ltd Country of Publication: England NLM ID: 8207483 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-6351 (Electronic) Linking ISSN: 02786915 NLM ISO Abbreviation: Food Chem Toxicol Subsets: MEDLINE

MeSH Terms: Furaldehyde*/analogs & derivatives , Furaldehyde*/toxicity , Epithelial Cells*/drug effects , Epithelial Cells*/metabolism , Intestinal Mucosa*/drug effects , Intestinal Mucosa*/cytology , Intestinal Mucosa*/metabolism , MAP Kinase Signaling System*/drug effects , MAP Kinase Signaling System*/genetics , Intestines*/cytology , Intestines*/drug effects, Apoptosis/drug effects ; Reactive Oxygen Species/metabolism ; Oxidative Stress/drug effects ; Cell Proliferation/drug effects ; Gene Expression Regulation/drug effects ; NF-kappa B/metabolism ; NF-kappa B/genetics ; Interleukin-6/metabolism ; Interleukin-6/genetics ; Humans ; Cell Line

Spautin-1 inhibits osteoclast differentiation and attenuates bone loss by blocking USP10/JIP1-mediated JNK pathway.

Authors: Chen X; School of Pharmaceutical Sciences, Marshall Laboratory of Biomedical Engineering, Shenzhen University, Shenzhen, China., Xiao Y; Guangdong Provincial Key Laboratory of Infection Immunity and Inflammation, Department of Immunology, Institute of Biological Therapy, Shenzhen University Medical School, Shenzhen University, Shenzhen, China., Wu H; Guangdong Provincial Key Laboratory of Infection Immunity and Inflammation, Department of Immunology, Institute of Biological Therapy, Shenzhen University Medical School, Shenzhen University, Shenzhen, China., Zhong M; Department of Spine Surgery, Ganzhou People's Hospital, Ganzhou 341000, China., Zhong R; Department of Neurosurgery, Shenzhen Second People's Hospital, The First Affiliated Hospital of Shenzhen University, Shenzhen University Medical School, Shenzhen University, Shenzhen 518055, China., Chen S; Guangdong Provincial Key Laboratory of Infection Immunity and Inflammation, Department of Immunology, Institute of Biological Therapy, Shenzhen University Medical School, Shenzhen University, Shenzhen, China., Tang H; Guangdong Provincial Key Laboratory of Infection Immunity and Inflammation, Department of Immunology, Institute of Biological Therapy, Shenzhen University Medical School, Shenzhen University, Shenzhen, China., Di Q; Guangdong Provincial Key Laboratory of Infection Immunity and Inflammation, Department of Immunology, Institute of Biological Therapy, Shenzhen University Medical School, Shenzhen University, Shenzhen, China., Zhao X; Guangdong Provincial Key Laboratory of Infection Immunity and Inflammation, Department of Immunology, Institute of Biological Therapy, Shenzhen University Medical School, Shenzhen University, Shenzhen, China., Gao Y; School of Pharmaceutical Sciences, Marshall Laboratory of Biomedical Engineering, Shenzhen University, Shenzhen, China., Chen W; Guangdong Provincial Key Laboratory of Infection Immunity and Inflammation, Department of Immunology, Institute of Biological Therapy, Shenzhen University Medical School, Shenzhen University, Shenzhen, China., Huang Q; Department of Pediatric Orthopaedics, Shenzhen Children's Hospital, Shenzhen University Medical School, Shenzhen University, Shenzhen 518035, China. Electronic address: hqi0606@163.com., Chen W; School of Pharmaceutical Sciences, Marshall Laboratory of Biomedical Engineering, Shenzhen University, Shenzhen, China; Guangdong Provincial Key Laboratory of Infection Immunity and Inflammation, Department of Immunology, Institute of Biological Therapy, Shenzhen University Medical School, Shenzhen University, Shenzhen, China. Electronic address: cwl@szu.edu.cn.

Source: Biochemical pharmacology [Biochem Pharmacol] 2026 Aug; Vol. 250 (Pt 1), pp. 117996. Date of Electronic Publication: 2026 Apr 20.

Publication Type: Journal Article

Journal Info: Publisher: Elsevier Science Country of Publication: England NLM ID: 0101032 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-2968 (Electronic) Linking ISSN: 00062952 NLM ISO Abbreviation: Biochem Pharmacol Subsets: MEDLINE

MeSH Terms: Osteoclasts*/drug effects , Osteoclasts*/metabolism , Osteoclasts*/cytology , Cell Differentiation*/drug effects , Cell Differentiation*/physiology , Ubiquitin Thiolesterase*/metabolism , Ubiquitin Thiolesterase*/antagonists & inhibitors , Bone Resorption*/metabolism , Bone Resorption*/drug therapy , Bone Resorption*/prevention & control , Adaptor Proteins, Signal Transducing*/metabolism , Adaptor Proteins, Signal Transducing*/antagonists & inhibitors , MAP Kinase Signaling System*/drug effects , MAP Kinase Signaling System*/physiology, Animals ; Mice ; Mice, Inbred C57BL ; Male ; Humans ; RANK Ligand ; Cells, Cultured ; Intracellular Signaling Peptides and Proteins

Cipepofol attenuates endothelial barrier dysfunction in acute lung injury through DUSP1-dependent suppression of MAPK signaling.

Authors: Zhou S; Department of Anesthesiology, Sixth People's Hospital Affiliated with Shanghai Jiao Tong University School of Medicine, Shanghai 200233, China; College of Fisheries and Life Science, Shanghai Ocean University, Shanghai 201306, China., He X; Department of Anesthesiology, Sixth People's Hospital Affiliated with Shanghai Jiao Tong University School of Medicine, Shanghai 200233, China; College of Fisheries and Life Science, Shanghai Ocean University, Shanghai 201306, China., Ni X; Department of Anesthesiology, Sixth People's Hospital Affiliated with Shanghai Jiao Tong University School of Medicine, Shanghai 200233, China; College of Fisheries and Life Science, Shanghai Ocean University, Shanghai 201306, China., Wang A; Department of Anesthesiology, Sixth People's Hospital Affiliated with Shanghai Jiao Tong University School of Medicine, Shanghai 200233, China. Electronic address: wangaz@sjtu.edu.cn., Xu X; Department of Anesthesiology, Sixth People's Hospital Affiliated with Shanghai Jiao Tong University School of Medicine, Shanghai 200233, China. Electronic address: 2015xuxiaotao@sjtu.edu.cn.

Source: Biochemical pharmacology [Biochem Pharmacol] 2026 Aug; Vol. 250 (Pt 1), pp. 117995. Date of Electronic Publication: 2026 Apr 19.

Publication Type: Journal Article

Journal Info: Publisher: Elsevier Science Country of Publication: England NLM ID: 0101032 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-2968 (Electronic) Linking ISSN: 00062952 NLM ISO Abbreviation: Biochem Pharmacol Subsets: MEDLINE

MeSH Terms: Acute Lung Injury*/metabolism , Acute Lung Injury*/drug therapy , Acute Lung Injury*/pathology , MAP Kinase Signaling System*/drug effects , MAP Kinase Signaling System*/physiology , Dual Specificity Phosphatase 1*/metabolism , Dual Specificity Phosphatase 1*/genetics, Human Umbilical Vein Endothelial Cells/drug effects ; Human Umbilical Vein Endothelial Cells/metabolism ; Sepsis/drug therapy ; Sepsis/metabolism ; Receptors, GABA-A/metabolism ; Capillary Permeability/drug effects ; Animals ; Humans ; Male ; Mice ; Mice, Inbred C57BL

Regulation of LPS-induced neuroinflammation in BV-2 cells by mung bean-derived chlorophyll metal salts via the NF-κB/MAPK signaling pathway.

Authors: Su Y; Key Laboratory of Agro-Products Processing Technology of Shandong Province, Key Laboratory of Novel Food Resources Processing Ministry of Agriculture, Institute of Food & Nutrition Science and Technology, Shandong Academy of Agricultural Sciences, Jinan 250100, China; College of Food and Biotechnology, Hebei University of Science and Technology, Shijiazhuang 050018, China., Wang X; Key Laboratory of Agro-Products Processing Technology of Shandong Province, Key Laboratory of Novel Food Resources Processing Ministry of Agriculture, Institute of Food & Nutrition Science and Technology, Shandong Academy of Agricultural Sciences, Jinan 250100, China. Electronic address: xinkunwang2016@163.com., Fan J; Key Laboratory of Agro-Products Processing Technology of Shandong Province, Key Laboratory of Novel Food Resources Processing Ministry of Agriculture, Institute of Food & Nutrition Science and Technology, Shandong Academy of Agricultural Sciences, Jinan 250100, China., Li Y; College of Food and Biotechnology, Hebei University of Science and Technology, Shijiazhuang 050018, China., Wu J; School of Food Science and Technology, Henan Institute of Science and Technology, Xinxiang 453003, China., Lodi RS; Key Laboratory of Agro-Products Processing Technology of Shandong Province, Key Laboratory of Novel Food Resources Processing Ministry of Agriculture, Institute of Food & Nutrition Science and Technology, Shandong Academy of Agricultural Sciences, Jinan 250100, China., Wang Z; College of Food and Biotechnology, Hebei University of Science and Technology, Shijiazhuang 050018, China. Electronic address: zhxwang0311@163.com., Peng L; Key Laboratory of Agro-Products Processing Technology of Shandong Province, Key Laboratory of Novel Food Resources Processing Ministry of Agriculture, Institute of Food & Nutrition Science and Technology, Shandong Academy of Agricultural Sciences, Jinan 250100, China. Electronic address: penglizeng@sdnu.edu.cn.

Source: Food research international (Ottawa, Ont.) [Food Res Int] 2026 Oct 31; Vol. 242 (Pt 3), pp. 120044. Date of Electronic Publication: 2026 Jul 18.

Publication Type: Journal Article

Journal Info: Publisher: Published on behalf of the Canadian Institute of Food Science and Technology by Elsevier Applied Science Country of Publication: Canada NLM ID: 9210143 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-7145 (Electronic) Linking ISSN: 09639969 NLM ISO Abbreviation: Food Res Int Subsets: MEDLINE

MeSH Terms: NF-kappa B*/metabolism , Chlorophyll*/pharmacology , Chlorophyll*/chemistry , MAP Kinase Signaling System*/drug effects , Anti-Inflammatory Agents*/pharmacology , Fabaceae*/chemistry , Microglia*/drug effects , Microglia*/metabolism , Neuroinflammatory Diseases*/chemically induced , Neuroinflammatory Diseases*/metabolism , Lipopolysaccharides*, Signal Transduction/drug effects ; Animals ; Mice ; Cell Line ; Chlorophyllides

Dietary anthocyanins and the MAPK signaling pathway: from food sources to molecular mechanisms.

Authors: Luo J; School of Food & Pharmaceutical Science and Technology, Guangzhou College of Technology and Business, Guangzhou 510850, China., Luo J; Food Science and Technology Program, Department of Life Sciences, Beijing Normal-Hong Kong Baptist University, Zhuhai, Guangdong 519087, China; School of Chinese Medicine, Hong Kong Baptist University, Hong Kong, China., Han B; Food Science and Technology Program, Department of Life Sciences, Beijing Normal-Hong Kong Baptist University, Zhuhai, Guangdong 519087, China; School of Chinese Medicine, Hong Kong Baptist University, Hong Kong, China., Xu B; Food Science and Technology Program, Department of Life Sciences, Beijing Normal-Hong Kong Baptist University, Zhuhai, Guangdong 519087, China. Electronic address: baojunxu@bnbu.edu.cn.

Source: Food research international (Ottawa, Ont.) [Food Res Int] 2026 Oct 31; Vol. 242 (Pt 2), pp. 119932. Date of Electronic Publication: 2026 Jul 06.

Publication Type: Journal Article; Review

Journal Info: Publisher: Published on behalf of the Canadian Institute of Food Science and Technology by Elsevier Applied Science Country of Publication: Canada NLM ID: 9210143 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-7145 (Electronic) Linking ISSN: 09639969 NLM ISO Abbreviation: Food Res Int Subsets: MEDLINE

MeSH Terms: Anthocyanins*/pharmacology , Anthocyanins*/administration & dosage , MAP Kinase Signaling System*/drug effects , Diet*, Humans ; Animals ; Inflammation

Fermentation with aspergillus costiformis enhances the anti-migratory activity of Aquilaria sinensis leaves with possible involvement of MAPK-related pathways.

Authors: Wu L; College of Biomass Science and Engineering, Sichuan University, Chengdu 610065, China. Electronic address: wulianqun23@163.com., Zhu X; School of Public Health, Chengdu University of Traditional Chinese Medicine, Chengdu 611137, China. Electronic address: zxzqyc0909@163.com., Wang X; College of Biomass Science and Engineering, Sichuan University, Chengdu 610065, China. Electronic address: 17729974511@163.com., Wu Y; College of Biomass Science and Engineering, Sichuan University, Chengdu 610065, China. Electronic address: wyp9202@163.com., Bu Q; West China School of Public Health and West China Fourth Hospital, Sichuan University, Chengdu 610041, China. Electronic address: buqian7978@scu.edu.cn., Dai T; Guosen Tianxiang (Hainan) Technology Co., Ltd., Hainan 571199, China. Electronic address: dai2277@163.com., Wen X; Institute of Plant and Food Science, Department of Biology, Southern University of Science and Technology (SUSTech), Shenzhen, Guangdong 518055, China. Electronic address: wenx@sustech.edu.cn., Zhong K; College of Biomass Science and Engineering, Sichuan University, Chengdu 610065, China. Electronic address: eric211@163.com., Guo H; Institute of Plant and Food Science, Department of Biology, Southern University of Science and Technology (SUSTech), Shenzhen, Guangdong 518055, China. Electronic address: guohw@sustech.edu.cn., Gao H; College of Biomass Science and Engineering, Sichuan University, Chengdu 610065, China. Electronic address: gao523421@outlook.com.

Source: Food research international (Ottawa, Ont.) [Food Res Int] 2026 Oct 31; Vol. 242 (Pt 2), pp. 119955. Date of Electronic Publication: 2026 Jul 10.

Publication Type: Journal Article

Journal Info: Publisher: Published on behalf of the Canadian Institute of Food Science and Technology by Elsevier Applied Science Country of Publication: Canada NLM ID: 9210143 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-7145 (Electronic) Linking ISSN: 09639969 NLM ISO Abbreviation: Food Res Int Subsets: MEDLINE

MeSH Terms: Aspergillus*/metabolism , Plant Leaves*/chemistry , Thymelaeaceae*/chemistry , Thymelaeaceae*/metabolism , Plant Extracts*/pharmacology , Cell Movement*/drug effects , MAP Kinase Signaling System*/drug effects , Fermentation*, Cell Proliferation/drug effects ; Humans ; HeLa Cells ; Flavonoids

Carpesium abrotanoides extract attenuates chronic obstructive pulmonary disease-associated airway inflammation through inhibition of MAPK signaling.

Authors: Han YK; KM Science Research Division, Korea Institute of Oriental Medicine, Daejeon, 34054, Republic of Korea., Kim SY; KM Science Research Division, Korea Institute of Oriental Medicine, Daejeon, 34054, Republic of Korea., Yang WK; DJU Industry-University Cooperation Foundation, Daejeon University, Daejeon, 34520, Republic of Korea., Ji YE; DJU Industry-University Cooperation Foundation, Daejeon University, Daejeon, 34520, Republic of Korea., Kim SH; DJU Industry-University Cooperation Foundation, Daejeon University, Daejeon, 34520, Republic of Korea., Kim DS; KM Science Research Division, Korea Institute of Oriental Medicine, Daejeon, 34054, Republic of Korea., Sung YY; KM Science Research Division, Korea Institute of Oriental Medicine, Daejeon, 34054, Republic of Korea. Electronic address: yysung@kiom.re.kr.

Source: Journal of ethnopharmacology [J Ethnopharmacol] 2026 Oct 28; Vol. 369, pp. 121894. Date of Electronic Publication: 2026 May 26.

Publication Type: Journal Article

Journal Info: Publisher: Elsevier Sequoia Country of Publication: Ireland NLM ID: 7903310 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1872-7573 (Electronic) Linking ISSN: 03788741 NLM ISO Abbreviation: J Ethnopharmacol Subsets: MEDLINE

MeSH Terms: Plant Extracts*/pharmacology , Plant Extracts*/therapeutic use , Pulmonary Disease, Chronic Obstructive*/drug therapy , Pulmonary Disease, Chronic Obstructive*/pathology , Asteraceae*/chemistry , Anti-Inflammatory Agents*/pharmacology , Anti-Inflammatory Agents*/therapeutic use , Anti-Inflammatory Agents*/isolation & purification , MAP Kinase Signaling System*/drug effects , Pneumonia*/drug therapy, Bronchoalveolar Lavage Fluid/cytology ; Lung/drug effects ; Lung/pathology ; Cytokines/metabolism ; Mitogen-Activated Protein Kinases/metabolism ; Smoke/adverse effects ; Nitric Oxide/metabolism ; Animals ; Mice, Inbred BALB C ; Mice ; Lipopolysaccharides ; RAW 264.7 Cells ; Male ; Disease Models, Animal ; Female

A comparative analysis of the tomato MAPK cascade at the transcriptional and translational levels under low-temperature conditions.

Authors: Suhorukova AV; Timiryazev Institute of Plant Physiology, Russian Academy of Sciences, Moscow 127276, Russia., Klychkov IO; Timiryazev Institute of Plant Physiology, Russian Academy of Sciences, Moscow 127276, Russia., Goldenkova-Pavlova IV; Timiryazev Institute of Plant Physiology, Russian Academy of Sciences, Moscow 127276, Russia., Piotrovskii MS; Timiryazev Institute of Plant Physiology, Russian Academy of Sciences, Moscow 127276, Russia., Tyurin AA; Timiryazev Institute of Plant Physiology, Russian Academy of Sciences, Moscow 127276, Russia.

Source: Functional plant biology : FPB [Funct Plant Biol] 2026 Oct 23; Vol. 53 (10).

Publication Type: Journal Article; Comparative Study

Journal Info: Publisher: CSIRO Pub Country of Publication: Australia NLM ID: 101154361 Publication Model: Print Cited Medium: Internet ISSN: 1445-4416 (Electronic) Linking ISSN: 14454416 NLM ISO Abbreviation: Funct Plant Biol Subsets: MEDLINE

MeSH Terms: Solanum lycopersicum*/genetics , Solanum lycopersicum*/enzymology , Solanum lycopersicum*/physiology , MAP Kinase Signaling System*/genetics , Mitogen-Activated Protein Kinases*/metabolism , Mitogen-Activated Protein Kinases*/genetics , Plant Proteins*/genetics , Plant Proteins*/metabolism , Cold Temperature* , Protein Biosynthesis* , Transcription, Genetic*, RNA, Messenger/genetics ; RNA, Messenger/metabolism ; Polyribosomes/metabolism ; Gene Expression Regulation, Plant ; Stress, Physiological

miR-iab-4-3p fine-tunes JNK signaling via a negative feedback loop targeting kay in Drosophila.

Authors: Sun Z; College of Life Sciences, Shandong Agricultural University, Tai'an, 271018, China., Shi Y; College of Life Sciences, Shandong Agricultural University, Tai'an, 271018, China., Liu S; College of Life Sciences, Shandong Agricultural University, Tai'an, 271018, China., Liu Y; College of Life Sciences, Shandong Agricultural University, Tai'an, 271018, China., Liu Q; College of Life Sciences, Shandong Agricultural University, Tai'an, 271018, China., Zhao Y; College of Life Sciences, Shandong Agricultural University, Tai'an, 271018, China. Electronic address: yhzhao@sdau.edu.cn.

Source: Biochemical and biophysical research communications [Biochem Biophys Res Commun] 2026 Oct 22; Vol. 836, pp. 154586. Date of Electronic Publication: 2026 Sep 13.

Publication Type: Journal Article

Journal Info: Publisher: Elsevier Country of Publication: United States NLM ID: 0372516 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1090-2104 (Electronic) Linking ISSN: 0006291X NLM ISO Abbreviation: Biochem Biophys Res Commun Subsets: MEDLINE

MeSH Terms: MicroRNAs*/metabolism , MicroRNAs*/genetics , Drosophila Proteins*/metabolism , Drosophila Proteins*/genetics , Drosophila melanogaster*/genetics , Drosophila melanogaster*/metabolism , JNK Mitogen-Activated Protein Kinases*/metabolism , MAP Kinase Signaling System*, Transcription Factor AP-1/metabolism ; Transcription Factor AP-1/genetics ; Animals ; Feedback, Physiological ; 3' Untranslated Regions ; Mitogen-Activated Protein Kinase Kinases