Genetically Estimated Ancestry and the Risk of Pre-Eclampsia

Authors: Frances Conti-Ramsden, PhD, Kypros Nicolaides, PhD, Argyro Syngelaki, PhD, Peter Dixon, PhD, Catherine Williamson, PhD, Maria Tsoukaki, MD, Alan Wright, PhD, Lucy C. Chappell, PhD, Pirro G. Hysi, PhD, Antonio de Marvao, PhD

Source: JACC: Advances, Vol 4, Iss 12, Pp 102283- (2025)

Subject Terms: ethnicity, hypertension, pre-eclampsia, pregnancy, Diseases of the circulatory (Cardiovascular) system, RC666-701, Medical emergencies. Critical care. Intensive care. First aid, RC86-88.9

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2772963X25007124; https://doaj.org/toc/2772-963X

Access URL: https://doaj.org/article/37e5b11589fc4a999c10417688ed2e19

Inclusion of people with multiple long-term conditions in pregnancy research: patient, public and stakeholder involvement and engagement in a randomised controlled trial

Authors: Zoë Vowles, Danielle C. Ashworth, Rebecca L. Barron, Frances Conti-Ramsden, Hannah Wilson, Lisa Leighton, Louise Wall, Cherrelle Walter, Jenny Myers, Lucy C. Chappell

Source: Research Involvement and Engagement, Vol 10, Iss 1, Pp 1-13 (2024)

Subject Terms: PPIE, Patient and public involvement and engagement, Stakeholder engagement, Multiple long-term conditions, Maternity research, Pregnancy, Medicine, Medicine (General), R5-920

File Description: electronic resource

Relation: https://doaj.org/toc/2056-7529

Access URL: https://doaj.org/article/04c44c7e3e6c462a826827786c490aff

Pregnancy-Associated Cancer: A Systematic Review and Meta-Analysis

Authors: Ben Walters, MBChB, India Midwinter, BSc, MBBS, Carolyn A. Chew-Graham, MBChB, MD, Kelvin P. Jordan, PhD, Garima Sharma, MB, Lucy C. Chappell, MB, BCh, PhD, Emma J. Crosbie, MBChB, PhD, Purvi Parwani, MBBS, MPH, Mamas A. Mamas, BM BCh, DPhil, Pensée Wu, MBChB, MD(Res)

Source: Mayo Clinic Proceedings: Innovations, Quality & Outcomes, Vol 8, Iss 2, Pp 188-199 (2024)

Subject Terms: Medicine (General), R5-920

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2542454824000109; https://doaj.org/toc/2542-4548

Access URL: https://doaj.org/article/8bc42a0d86a3458a8a78d7ff9fde62d3

A treatment strategy with nifedipine versus labetalol for women with pregnancy hypertension: study protocol for a randomised controlled trial (Giant PANDA)

Authors: Danielle Ashworth, Cheryl Battersby, Debra Bick, Marcus Green, Pollyanna Hardy, Lisa Leighton, Laura A. Magee, Alisha Maher, Richard J. McManus, Catherine Moakes, R. Katie Morris, Catherine Nelson-Piercy, Jenie Sparkes, Oliver Rivero-Arias, Andrew Webb, Hannah Wilson, Jenny Myers, Lucy C. Chappell

Source: Trials, Vol 24, Iss 1, Pp 1-14 (2023)

Subject Terms: Hypertension, Pregnancy, Randomised controlled trial, Antihypertensives, Blood pressure, Medicine (General), R5-920

File Description: electronic resource

Relation: https://doaj.org/toc/1745-6215

Access URL: https://doaj.org/article/224fe3f3ab354e9c9980ca977e842906

5-HT2C Receptors in the BNST Modulate Contextual Fear Conditioning Without Affecting Acute Early Life Stress-Enhanced Fear Learning in Adult Rats

Authors: Brianna L. Minshall, Catherine F. Wasylyshyn, Kate M. Brand, Caroline M. Bartoszek, Kennedy A. Seipel, Madeline M. Booms, Lucy C. Chappell, Amanda N. Reichert, Jacob R. Dowell, Angeles L. Buck, Henry T. Beckett, Christopher A. Lowry, Jennifer J. Quinn

Source: Brain Sciences, Vol 14, Iss 12, p 1287 (2024)

Subject Terms: early-life stress, post-traumatic stress disorder, serotonin, bed nucleus of the stria terminalis, stress-enhanced fear learning, SEFL, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571

File Description: electronic resource

Relation: https://www.mdpi.com/2076-3425/14/12/1287; https://doaj.org/toc/2076-3425

Access URL: https://doaj.org/article/9a24c6707c4b410b9472d6164f8be583

Placental growth fActor Repeat sampling for Reduction of adverse perinatal Outcomes in women with suspecTed pre-eclampsia: study protocol for a randomised controlled trial (PARROT-2)

Authors: Alice Hurrell, Jenie Sparkes, Kate Duhig, Paul T. Seed, Jenny Myers, Cheryl Battersby, Katherine Clark, Marcus Green, Rachael M. Hunter, Andrew H. Shennan, Lucy C. Chappell, Louise Webster

Source: Trials, Vol 23, Iss 1, Pp 1-12 (2022)

Subject Terms: Pre-eclampsia, Angiogenic biomarkers, Placental growth factor, Soluble fms-like tyrosine kinase 1, Medicine (General), R5-920

File Description: electronic resource

Relation: https://doaj.org/toc/1745-6215

Access URL: https://doaj.org/article/cf6e8995014344c5bd8ac1ca6b418c41

Postnatal health and care following hypertensive disorders in pregnancy: a prospective cohort study (BPiPP study)

Authors: Danielle C. Ashworth, Liza Bowen, Sophie P. Maule, Paul T. Seed, Marcus Green, Debra Bick, BPiPP study group, Lucy C. Chappell

Source: BMC Pregnancy and Childbirth, Vol 22, Iss 1, Pp 1-12 (2022)

Subject Terms: Pregnancy, Hypertension, High blood pressure, Postnatal, Gynecology and obstetrics, RG1-991

File Description: electronic resource

Relation: https://doaj.org/toc/1471-2393

Access URL: https://doaj.org/article/36603bce1e7543dda9c276931775e3d7

The effectiveness of decision aids for pregnancy related decision-making in women with pre-pregnancy morbidity; systematic review and meta-analysis

Authors: Rebecca Whybrow, Louise M. Webster, Paul T. Seed, Jane Sandall, Lucy C. Chappell

Source: BMC Pregnancy and Childbirth, Vol 22, Iss 1, Pp 1-12 (2022)

Subject Terms: Decision aid, Shared decision-making, Informed decision, Obstetric medicine, Pre-existing medical condition, Previous caesarean section, Gynecology and obstetrics, RG1-991

File Description: electronic resource

Relation: https://doaj.org/toc/1471-2393

Access URL: https://doaj.org/article/c800f5a8758e4b00912cfd55658e353b

Planned early delivery for late preterm pre-eclampsia in a low- and middle-income setting: a feasibility study

Authors: Alice Beardmore-Gray, Nicola Vousden, Sergio A. Silverio, Umesh Charantimath, Geetanjali Katageri, Mrutyunjaya Bellad, Sebastian Chinkoyo, Bellington Vwalika, Shivaprasad Goudar, Jane Sandall, Lucy C. Chappell, Andrew H. Shennan

Source: Reproductive Health, Vol 18, Iss 1, Pp 1-17 (2021)

Subject Terms: Pregnancy, Pre-eclampsia, Delivery, Low- and middle-income, Feasibility, Acceptability, Gynecology and obstetrics, RG1-991

File Description: electronic resource

Relation: https://doaj.org/toc/1742-4755

Access URL: https://doaj.org/article/cbf2c0b5c6744f0c8af455fc8bed9780

Effect of the CRADLE vital signs alert device intervention on referrals for obstetric haemorrhage in low-middle income countries: a secondary analysis of a stepped- wedge cluster-randomised control trial

Authors: Lucie Giblin, Nicola Vousden, Hannah Nathan, Francis Gidiri, Shivaprasad Goudar, Umesh Charantimath, Jane Sandall, Paul T. Seed, Lucy C. Chappell, Andrew H. Shennan

Source: BMC Pregnancy and Childbirth, Vol 21, Iss 1, Pp 1-7 (2021)

Subject Terms: Referral, Shock index, Obstetric haemorrhage, Bleeding, Triage, Resource allocation, Gynecology and obstetrics, RG1-991

File Description: electronic resource

Relation: https://doaj.org/toc/1471-2393

Access URL: https://doaj.org/article/b2efe94741834419b1bf67fcb3b90114

External validation of prognostic models predicting pre-eclampsia: individual participant data meta-analysis

Authors: Kym I. E. Snell, John Allotey, Melanie Smuk, Richard Hooper, Claire Chan, Asif Ahmed, Lucy C. Chappell, Peter Von Dadelszen, Marcus Green, Louise Kenny, Asma Khalil, Khalid S. Khan, Ben W. Mol, Jenny Myers, Lucilla Poston, Basky Thilaganathan, Anne C. Staff, Gordon C. S. Smith, Wessel Ganzevoort, Hannele Laivuori, Anthony O. Odibo, Javier Arenas Ramírez, John Kingdom, George Daskalakis, Diane Farrar, Ahmet A. Baschat, Paul T. Seed, Federico Prefumo, Fabricio da Silva Costa, Henk Groen, Francois Audibert, Jacques Masse, Ragnhild B. Skråstad, Kjell Å. Salvesen, Camilla Haavaldsen, Chie Nagata, Alice R. Rumbold, Seppo Heinonen, Lisa M. Askie, Luc J. M. Smits, Christina A. Vinter, Per Magnus, Kajantie Eero, Pia M. Villa, Anne K. Jenum, Louise B. Andersen, Jane E. Norman, Akihide Ohkuchi, Anne Eskild, Sohinee Bhattacharya, Fionnuala M. McAuliffe, Alberto Galindo, Ignacio Herraiz, Lionel Carbillon, Kerstin Klipstein-Grobusch, Seon Ae Yeo, Joyce L. Browne, Karel G. M. Moons, Richard D. Riley, Shakila Thangaratinam, for the IPPIC Collaborative Network

Source: BMC Medicine, Vol 18, Iss 1, Pp 1-18 (2020)

Subject Terms: Pre-eclampsia, External validation, Prediction model, Individual participant data, Medicine

File Description: electronic resource

Relation: http://link.springer.com/article/10.1186/s12916-020-01766-9; https://doaj.org/toc/1741-7015

Access URL: https://doaj.org/article/aa967abb5a8146c29455aad1bee4df5a

Placental growth factor for the prognosis of women with preeclampsia (fullPIERS model extension): context matters

Authors: U. Vivian Ukah, Beth A. Payne, Jennifer A. Hutcheon, Lucy C. Chappell, Paul T. Seed, Frances Inez Conti-Ramsden, J. Mark Ansermino, Laura A. Magee, Peter von Dadelszen, for the fullPIERS Group

Source: BMC Pregnancy and Childbirth, Vol 20, Iss 1, Pp 1-9 (2020)

Subject Terms: Preeclampsia, Prediction, Placental growth factor, Prognosis, Hypertension, Model extension, Gynecology and obstetrics, RG1-991

File Description: electronic resource

Relation: http://link.springer.com/article/10.1186/s12884-020-03332-w; https://doaj.org/toc/1471-2393

Access URL: https://doaj.org/article/859437f101984798aa72467393e3843f

Perturbation of placental protein glycosylation by endoplasmic reticulum stress promotes maladaptation of maternal hepatic glucose metabolism

Authors: Hong Wa Yung, Xiaohui Zhao, Luke Glover, Charlotte Burrin, Poh-Choo Pang, Carolyn J.P. Jones, Carolyn Gill, Kate Duhig, Matts Olovsson, Lucy C. Chappell, Stuart M. Haslam, Anne Dell, Graham J. Burton, D. Stephen Charnock-Jones

Source: iScience, Vol 26, Iss 1, Pp 105911- (2023)

Subject Terms: Pregnancy, Biological sciences, Human metabolism, Science

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2589004222021848; https://doaj.org/toc/2589-0042

Access URL: https://doaj.org/article/6e34dcb2f7314238b61be21430ba8238

Optimising the monitoring and management of raised blood pressure including proteinuria testing during pregnancy: the BUMP research programme including 2 RCTs

Authors: Richard J McManus, Lucy C Chappell, Katherine L Tucker, Lisa Hinton, Oliver Rivero-Arias, Julie Allen, Rebecca Band, Helen E Campbell, Alison Chisholm, Marcus Green, Ushma Galal, Sheila Greenfield, James Hodgkinson, Bethany Jakubowski, Layla Lavallee, Paul Leeson, Lucy H Mackillop, Christine McCourt, Sam Mort, Louise M Pealing, Jane Sandall, Richard J Stevens, Lionel Tarassenko, Hannah Wilson, Lucy Yardley, Ly-Mee Yu

Source: Programme Grants for Applied Research. :1-50

File Description: text

Access URL: https://eprints.soton.ac.uk/510983/1/3050474.pdf

In‐Hospital Complications in Pregnancies Conceived by Assisted Reproductive Technology

Authors: Pensée Wu, Garima V. Sharma, Laxmi S. Mehta, Carolyn A. Chew‐Graham, Gina P. Lundberg, Kara A. Nerenberg, Michelle M. Graham, Lucy C. Chappell, Umesh T. Kadam, Kelvin P. Jordan, Mamas A. Mamas

Source: Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 11, Iss 5 (2022)

Subject Terms: cardiovascular disease risk factors, in vitro fertilization, pregnancy, prevention, Diseases of the circulatory (Cardiovascular) system, RC666-701

File Description: electronic resource

Relation: https://doaj.org/toc/2047-9980

Access URL: https://doaj.org/article/a72eeef8618e4b2fac20e5364c6e89d3

The ability of late pregnancy maternal tests to predict adverse pregnancy outcomes associated with placental dysfunction (specifically fetal growth restriction and pre-eclampsia): a protocol for a systematic review and meta-analysis of prognostic accuracy studies

Authors: Melanie Griffin, Alexander E. P. Heazell, Lucy C. Chappell, Jian Zhao, Deborah A. Lawlor

Source: Systematic Reviews, Vol 9, Iss 1, Pp 1-6 (2020)

Subject Terms: Pre-eclampsia, Small for gestational age (SGA), Fetal growth restriction (FGR), Neonatal growth restriction/growth restriction in the newborn (NGR), Stillbirth, Biomarker, Medicine

File Description: electronic resource

Relation: http://link.springer.com/article/10.1186/s13643-020-01334-5; https://doaj.org/toc/2046-4053

Access URL: https://doaj.org/article/87099f7961ae466e9d0e7950cc90441e

Intervention planning and modification of the BUMP intervention: a digital intervention for the early detection of raised blood pressure in pregnancy

Authors: Rebecca Band, Lisa Hinton, Katherine L. Tucker, Lucy C. Chappell, Carole Crawford, Marloes Franssen, Sheila Greenfield, James Hodgkinson, Christine McCourt, Richard J. McManus, Jane Sandall, Mauro Dala Santos, Carmelo Velardo, Lucy Yardley

Source: Pilot and Feasibility Studies, Vol 5, Iss 1, Pp 1-12 (2019)

Subject Terms: Hypertension, Pregnancy, Pre-eclampsia, Digital intervention, Intervention planning, Person-based approach, Medicine (General), R5-920

File Description: electronic resource

Relation: https://doaj.org/toc/2055-5784

Access URL: https://doaj.org/article/69d96d9b62684caebb565618cea05129

Cost Comparison of Repeat Placental Growth Factor-Based Testing in Women with Suspected Preterm Pre-eclampsia, Compared to Usual Care: The PARROT-2 Trial

Authors: Alice Hurrell, Louise Webster, Jenie Sparkes, Cheryl Battersby, Katherine Clark, Kate E Duhig, Marcus Green, Paul T Seed, Zoe Vowles, Jenny Myers, Andrew H Shennan, Lucy C Chappell, Rachael M Hunter, Carolyn Gill, Sian McDonnell, Beth Peers, Angela Yulia, Orla Ferry, Martin Maher, Francis Pickering, Annabel Smith, Hilary Thompson, Sambita Basak, Lucy Dudgeon, Jo Ficquet, Mel Rich, Clare O’Brien, Seren Willson, Nikolaos Chados, Linda Bishop, Rachna Bahl, Brittany Smart, Rita Arya, Lindsay Roughley, Anku Mehta, Deniesha Campbell, Jo Girling, Grace Ryan, Lauren Trepte, Chandrima Biswas, Chinwe Obiozo, Lynda Verghese, Ashwin Ahuja, Sarah Davies, Katie Morris, Jessica Davison, Maeve Regan, Natalie Barry, Mel McBean, Jacqui Jennings, Andrew Sharp, Siobhan Holt, Laura Stirrat, Elaine Jack, Mihraban Bapir, Sharon Gowans, Hazel Alexander, Kim Hinshaw, Lesley Hewitt

Source: Pharmacoecon Open

Subject Terms: Original Research Article

Access URL: https://pubmed.ncbi.nlm.nih.gov/41493740
https://pmc.ncbi.nlm.nih.gov/articles/PMC13000100/
https://pubmed.ncbi.nlm.nih.gov/41493740/
https://doi.org/10.1007/s41669-025-00629-4

Diagnostic Indicators of Superimposed Preeclampsia in Women With CKD

Authors: Kate Wiles, Kate Bramham, Paul T. Seed, Lesia O. Kurlak, Hiten D. Mistry, Catherine Nelson-Piercy, Liz Lightstone, Lucy C. Chappell

Source: Kidney International Reports, Vol 4, Iss 6, Pp 842-853 (2019)

Subject Terms: Diseases of the genitourinary system. Urology, RC870-923

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2468024919301172; https://doaj.org/toc/2468-0249

Access URL: https://doaj.org/article/ff28a4d3b14346578ec828387ee87947

Exploring the effect of implementation and context on a stepped-wedge randomised controlled trial of a vital sign triage device in routine maternity care in low-resource settings

Authors: Nicola Vousden, Elodie Lawley, Paul T. Seed, Muchabayiwa Francis Gidiri, Umesh Charantimath, Grace Makonyola, Adrian Brown, Lomi Yadeta, Rebecca Best, Sebastian Chinkoyo, Bellington Vwalika, Annettee Nakimuli, James Ditai, Grace Greene, Lucy C. Chappell, Jane Sandall, Andrew H. Shennan, on behalf of the CRADLE Trial Collaborative Group

Source: Implementation Science, Vol 14, Iss 1, Pp 1-16 (2019)

Subject Terms: Implementation strength, Hybrid trial, Complex intervention, Global health, Maternal mortality, Medicine (General), R5-920

File Description: electronic resource

Relation: http://link.springer.com/article/10.1186/s13012-019-0885-3; https://doaj.org/toc/1748-5908

Access URL: https://doaj.org/article/e3f316cb39af40e0972ef4cef9ef65f0