Multidimensional physical fitness is associated with reduced dementia risk through proteomic and neuroimaging pathways: a prospective cohort study of the UK Biobank

Συγγραφείς: Sun, Yiqing, Lin, Runyu, Qin, Jiayue, Pan, Feiyue, Li, Bingjie, Yao, Zhigang

Θεματικοί όροι: Applications, Quantitative Methods

Σύνδεσμος πρόσβασης: http://arxiv.org/abs/2604.03952

CellScope: high-performance cell atlas workflow with tree-structured representation

Συγγραφείς: Li, Bingjie, Lin, Runyu, Ni, Tianhao, Yan, Guanao, Burns, Mannix, Li, Jingyi Jessica, Yao, Zhigang

Πηγή: Nature Communications. 17(1)

Θεματικοί όροι: 31 Biological Sciences (for-2020), 3102 Bioinformatics and Computational Biology (for-2020), Bioengineering (rcdc), Human Genome (rcdc), Genetics (rcdc), 1.1 Normal biological development and functioning (hrcs-rac), Generic health relevance (hrcs-hc), Animals (mesh), Humans (mesh), Cluster Analysis (mesh), Gene Expression Profiling (mesh), Computational Biology (mesh), Cell Lineage (mesh), Algorithms (mesh), Software (mesh), Workflow (mesh), Single-Cell Analysis (mesh), Single-Cell Analysis (mesh), Humans (mesh), Workflow (mesh), Algorithms (mesh), Software (mesh), Cluster Analysis (mesh), Computational Biology (mesh), Cell Lineage (mesh), Gene Expression Profiling (mesh), Animals (mesh)

Περιγραφή αρχείου: application/pdf

Σύνδεσμος πρόσβασης: https://escholarship.org/uc/item/5qn8k5m8
https://escholarship.org/content/qt5qn8k5m8/qt5qn8k5m8.pdf

Manifold fitting reveals metabolomic heterogeneity and disease associations in UK Biobank populations.

Συγγραφείς: Li B; Department of Statistics and Data Science, National University of Singapore, Singapore 117546, Singapore., Su J; Department of Statistics and Data Science, National University of Singapore, Singapore 117546, Singapore., Lin R; Department of Statistics and Data Science, National University of Singapore, Singapore 117546, Singapore., Yau ST; Yau Mathematical Sciences Center, Tsinghua University, Jingzhai, Beijing 100084, China., Yao Z; Department of Statistics and Data Science, National University of Singapore, Singapore 117546, Singapore.

Πηγή: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2025 Jun 03; Vol. 122 (22), pp. e2500001122. Date of Electronic Publication: 2025 May 28.

Τύπος έκδοσης: Journal Article

Στοιχεία περιοδικού: Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1091-6490 (Electronic) Linking ISSN: 00278424 NLM ISO Abbreviation: Proc Natl Acad Sci U S A Subsets: MEDLINE

Ιατρικοί όροι (MeSH): Metabolomics*/methods , Biological Specimen Banks* , Metabolome*, Biomarkers/metabolism ; Humans ; United Kingdom ; Male ; Female ; Middle Aged ; Aged ; Magnetic Resonance Spectroscopy ; UK Biobank