Characterisation of the immune repertoire of a humanised transgenic mouse through immunophenotyping and high-throughput sequencing

Συγγραφείς: Richardson, E, Binter, Š, Kosmac, M, Ghraichy, M, von Niederhäusern, V, Kovaltsuk, A, Galson, JD, Trück, J, Kelly, DF, Deane, CM, Kellam, P, Watson, SJ

Relation: https://doi.org/10.7554/elife.81629

Διαθεσιμότητα: https://doi.org/10.7554/elife.81629
https://ora.ox.ac.uk/objects/uuid:06ebdfbc-3c15-4a98-bbdb-683363a5297f

Prediction and characterisation of the human B cell response to a heterologous two-dose Ebola vaccine

Συγγραφείς: O’Connor, D, Clutterbuck, EA, Gibani, MM, Bibi, S, Sanders, KA, Makinson, R, Kelly, DF, Pollard, AJ

Πηγή: Nat Commun

Θεματικοί όροι: B-Lymphocytes, Plasma Cells, Vaccination, Receptors, Antigen, B-Cell, Hemorrhagic Fever, Ebola, Ebolavirus, Antibodies, Viral, Article, Machine Learning, Immunoglobulin G, Humans, Female, Ebola Vaccines, Single-Cell Analysis, Immunologic Memory

Σύνδεσμος πρόσβασης: https://pubmed.ncbi.nlm.nih.gov/40634393
https://ora.ox.ac.uk/objects/uuid:a30113d6-c5e8-4f6c-9042-5c052cf93223
https://doi.org/10.1038/s41467-025-61571-x

Vitamin D may influence disease course in PIMS ‐ TS / MIS ‐C: An observational cohort study

Συγγραφείς: Charlesworth, JEG, Navarajasegaran, J, Kavirayani, A, Sarfatti, A, Adwani, S, Paulus, S, Segal, S, Gilchrist, JJ, Kelly, DF, Lees, EA

Συνεισφορές: Apollo - University of Cambridge Repository

Πηγή: Pediatr Int

Θεματικοί όροι: Male, Adolescent, SARS-CoV-2, COVID-19, Infant, Prognosis, Severity of Illness Index, SARS‐CoV‐2, Systemic Inflammatory Response Syndrome, COVID-19 Drug Treatment, MIS‐C, Cohort Studies, pediatric infectious disease, COVID‐19, Child, Preschool, PIMS‐TS, Humans, Original Article, Female, Vitamin D, Child, Biomarkers, Retrospective Studies

Περιγραφή αρχείου: application/pdf; text/xml

Σύνδεσμος πρόσβασης: https://pubmed.ncbi.nlm.nih.gov/41099225
https://www.repository.cam.ac.uk/handle/1810/391059
https://doi.org/10.1111/ped.70241

A review of the prevention of mother-to-child transmission of human T-cell lymphotrophic virus type 1 (HTLV-1) with a proposed management algorithm

Συγγραφείς: Barr, RS, Drysdale, SB, Boullier, M, Lyall, H, Cook, L, Collins, GP, Kelly, DF, Phelan, L, Taylor, GP

Relation: https://doi.org/10.3389/fmed.2022.941647

Διαθεσιμότητα: https://doi.org/10.3389/fmed.2022.941647
https://ora.ox.ac.uk/objects/uuid:5d441ee4-4561-4654-9a19-85ed36543b88

Effect of childhood vaccination and antibiotic use on pneumococcal populations and genome-wide associations with disease among children in Nepal: an observational study

Συγγραφείς: Kandasamy, R, Lo, S, Gurung, M, Carter, MJ, Gladstone, R, Lees, J, Shrestha, S, Thorson, S, Bijukchhe, S, Gautam, MC, Shrestha, R, Gurung, S, Khadka, B, McGee, L, Breiman, RF, Murdoch, DR, Kelly, DF, Bentley, SD, Pollard, AJ

Πηγή: Lancet Microbe

Θεματικοί όροι: 0301 basic medicine, Vaccines, 0303 health sciences, Vaccines, Conjugate, Nepal/epidemiology, Vaccination, Articles, United States, Anti-Bacterial Agents/pharmacology, Anti-Bacterial Agents, 3. Good health, 03 medical and health sciences, Conjugate/pharmacology, Streptococcus pneumoniae, Nepal, Carrier State, Humans, Carrier State/epidemiology, Streptococcus pneumoniae/genetics, Genome-Wide Association Study

Σύνδεσμος πρόσβασης: https://pubmed.ncbi.nlm.nih.gov/35779566

Decline in pneumococcal vaccine serotype carriage, multiple-serotype carriage, and carriage density in Nepalese children after PCV10 introduction: a pre-post comparison study

Συγγραφείς: Kandasamy, R, Gurung, M, Shrestha, S, Gautam, MC, Kelly, S, Thorson, S, Ansari, I, Gould, K, Hinds, J, Kelly, DF, Murdoch, DR, Pollard, AJ

Relation: https://doi.org/10.1016/j.vaccine.2024.05.018

Διαθεσιμότητα: https://doi.org/10.1016/j.vaccine.2024.05.018
https://ora.ox.ac.uk/objects/uuid:2b104c4a-9444-4303-9c5d-e99b9995eee1

Computational mining of B cell receptor repertoires reveals antigen-specific and convergent responses to Ebola vaccination

Συγγραφείς: Richardson, E, Bibi, S, McLean, F, Schimanski, L, Rijal, P, Ghraichy, M, von Niederhäusern, V, Trück, J, Clutterbuck, EA, O’Connor, D, Luhn, K, Townsend, A, Peters, B, Pollard, AJ, Deane, CM, Kelly, DF

Relation: https://doi.org/10.3389/fimmu.2024.1383753

Διαθεσιμότητα: https://doi.org/10.3389/fimmu.2024.1383753
https://ora.ox.ac.uk/objects/uuid:c2e04aa2-ab5b-40c1-9562-f4f82cc59d01

Evaluation of acute and convalescent antibody concentration against pneumococcal capsular polysaccharides for the diagnosis of pneumococcal infection in children with community-acquired pneumonia

Συγγραφείς: Carter, MJ, Shrestha, S, O’Reilly, P, Gurung, P, Gurung, M, Thorson, S, Kandasamy, R, Voysey, M, O’Mahony, E, Kelly, S, Ansari, I, Shah, G, Amatya, P, Tcherniaeva, I, Berbers, G, Murdoch, DR, Pollard, AJ, Kelly, DF

Συνεισφορές: Group, PneumoNepal Study

Relation: https://doi.org/10.1097/INF.0000000000004185

Διαθεσιμότητα: https://doi.org/10.1097/INF.0000000000004185
https://ora.ox.ac.uk/objects/uuid:0bd6cdc0-6ae3-49d8-bdab-aa2ace2e5a1b

Molecular correlates of vaccine-induced protection against typhoid fever

Συγγραφείς: Zhu, H, Chelysheva, I, Cross, DL, Blackwell, L, Jin, C, Gibani, MM, Jones, E, Hill, J, Trück, J, Kelly, DF, Blohmke, C, Pollard, AJ, O'Connor, D

Relation: https://doi.org/10.1172/JCI169676

Διαθεσιμότητα: https://doi.org/10.1172/JCI169676
https://ora.ox.ac.uk/objects/uuid:288fcd86-f7b0-4482-854f-a15490b8a9b4

Genomic investigations of unexplained acute hepatitis in children

Συγγραφείς: Morfopoulou, S, Buddle, S, Torres Montaguth, OE, Atkinson, L, Guerra-Assunção, JA, Moradi Marjaneh, M, Zennezini Chiozzi, R, Storey, N, Campos, L, Hutchinson, JC, Counsell, JR, Pollara, G, Roy, S, Venturini, C, Antinao Diaz, JF, Siam, A, Tappouni, LJ, Asgarian, Z, Ng, J, Hanlon, KS, Lennon, A, McArdle, A, Czap, A, Rosenheim, J, Andrade, C, Anderson, G, Lee, JCD, Williams, R, Williams, CA, Tutill, H, Bayzid, N, Martin Bernal, LM, Macpherson, H, Montgomery, K-A, Moore, C, Templeton, K, Neill, C, Holden, M, Gunson, R, Shepherd, SJ, Shah, P, Cooray, S, Voice, M, Steele, M, Fink, C, Whittaker, TE, Santilli, G, Gissen, P, Kaufer, BB, Reich, J, Andreani, J, Simmonds, P, Paulus, SC, Pollard, AJ, Hopton, S, Miller, D, Oliver, Z, Beer, S, Ward, B, Lubinda, T, Kelly, S, O’Reilly, P, Kandasamy, R, Carter, MJ, O’Connor, D, Bibi, S, Kelly, DF, Carson, G, Merson, L

Συνεισφορές: Consortium, DIAMONDS, Consortium, PERFORM, Investigators, ISARIC 4C

Θεματικοί όροι: Paediatric research, Clinical microbiology

Διαθεσιμότητα: https://doi.org/10.1038/s41586-023-06003-w
https://ora.ox.ac.uk/objects/uuid:8ccd1706-5151-4bd6-91d2-17ea8bba0b0c

Comparison of two schedules of two-dose priming with the ten-valent pneumococcal conjugate vaccine in Nepalese children: an open-label, randomised non-inferiority controlled trial

Συγγραφείς: Kandasamy, R, Gurung, M, Thorson, S, Yu, LM, Galal, U, Voysey, M, Kelly, S, Wahl, B, Berbers, G, Finnegan, K, Ansari, I, Paudel, K, Murdoch, DR, O'Brien, KL, Kelly, DF, Goldblatt, D, Shrestha, S, Pollard, AJ

Συνεισφορές: Open Repository DS7.6 Demo

Πηγή: The Lancet Infectious Diseases. 19:156-164

Θεματικοί όροι: Immunity, Herd, Male, Secondary, 32 Biomedical and Clinical Sciences, anzsrc-for: 4202 Epidemiology, anzsrc-for: 1103 Clinical Sciences, Pneumococcal Vaccines, Immunogenicity, Vaccine, 0302 clinical medicine, Pediatric, Vaccines, Bacterial, 3 Good Health and Well Being, 16. Peace & justice, Immunogenicity, Antibodies, Bacterial, 3. Good health, Infectious Diseases, Streptococcus pneumoniae, Treatment Outcome, 3.4 Vaccines, anzsrc-for: 3202 Clinical sciences, Female, Infection, anzsrc-for: 1117 Public Health and Health Services, anzsrc-for: 1108 Medical Microbiology, Clinical Trials and Supportive Activities, Immunization, Secondary, Serogroup, Antibodies, Pneumococcal Infections, Vaccine Related, 03 medical and health sciences, anzsrc-for: 32 Biomedical and Clinical Sciences, Nepal, Clinical Research, Humans, Immunization Schedule, Conjugate, Vaccines, Conjugate, Prevention, Immunity, Infant, anzsrc-for: 3213 Paediatrics, Herd, 3213 Paediatrics, anzsrc-for: 3207 Medical microbiology, Immunoglobulin G, Immunization, Vaccine

Περιγραφή αρχείου: application/pdf

Σύνδεσμος πρόσβασης: https://discovery.ucl.ac.uk/10068031/3/Kandasamy_PIMMS_manuscript_LID_V1.3_clean.pdf
https://pubmed.ncbi.nlm.nih.gov/30635252
https://ora.ox.ac.uk/objects/uuid:9c574e7e-817a-42b5-a2a9-1725227f2bc9
https://doi.org/10.1016/s1473-3099(18)30568-1
https://discovery-pp.ucl.ac.uk/id/eprint/10068031/
https://hdl.handle.net/10029/622747

Effect of the of 10-valent pneumococcal conjugate vaccine in Nepal 4 years after introduction: an observational cohort study

Συγγραφείς: Shrestha, S, Gurung, M, Amatya, P, Bijukchhe, S, Bose, AS, Carter, MJ, Gautam, MC, Gurung, S, Hinds, J, Kandasamy, R, Kelly, S, Khadka, B, Maskey, P, Mujadidi, YF, O’Reilly, PJ, Pokhrel, B, Pradhan, R, Shah, GP, Wahl, B, O’Brien, KL, Knoll, MD, Murdoch, DR, Kelly, DF, Thorson, S, Voysey, M, Pollard, AJ

Συνεισφορές: group, PneumoNepal study

Διαθεσιμότητα: https://doi.org/10.1016/s2214-109x(22)00281-9
https://ora.ox.ac.uk/objects/uuid:ebf0eb3b-d27e-4cd7-b10a-c28a98a94219

Memory B Cell Activation Induced by Pertussis Booster Vaccination in Four Age Groups of Three Countries

Συγγραφείς: Versteegen, P, Barkoff, A, Valente Pinto, M, van de Kasteele, J, Knuutila, A, Bibi, S, de Rond, L, Teräsjärvi J, Sanders, K, de Zeeuw-Brouwer M, Luoto, R, Ten Hulscher, H, Clutterbuck, EA, Sanders, EA, Mertsola, J, Berbers, GA, He, Q, Kelly, DF, Buisman, A

Πηγή: Frontiers in Immunology. 13

Θεματικοί όροι: ta3123

Σύνδεσμος πρόσβασης: http://juuli.fi/Record/0399755822

Maturation of the human immunoglobulin heavy chain repertoire with age

Συγγραφείς: Ghraichy, M, Galson, JD, Kovaltsuk, A, von Niederhäusern, V, Pachlopnik Schmid, J, Recher, M, Jauch, AJ, Miho, E, Kelly, DF, Deane, CM, Trück, J

Relation: https://doi.org/10.3389/fimmu.2020.01734

Διαθεσιμότητα: https://doi.org/10.3389/fimmu.2020.01734
https://ora.ox.ac.uk/objects/uuid:aa4d71ed-1c55-423a-b8d2-af1ed2ce56b5

Persistence of immunity following 2-dose priming with a 10-valent pneumococcal conjugate vaccine at 6 and 10 weeks or 6 and 14 weeks of age in Nepalese toddlers

Συγγραφείς: Gurung, M, Bijukchhe, SM, Hariri, P, Voysey, M, Kandasamy, R, Thorson, S, Maskey, P, Pandit, R, Shrestha, B, Gautam, MC, Maharjan, M, Lama, L, Acharya, B, Basi, R, K C, M, O'Reilly, P, Shrestha, S, Ansari, I, Shah, GP, Kelly, S, O'Brien, KL, Goldblatt, D, Kelly, DF, Murdoch, DR, Pollard, AJ

Relation: https://doi.org/10.1097/inf.0000000000003223

Διαθεσιμότητα: https://doi.org/10.1097/inf.0000000000003223
https://ora.ox.ac.uk/objects/uuid:7679d923-e6be-4f3b-8a50-b8f607d01165

The ethics of overruling parental refusal of neonatal hepatitis B vaccination for babies born to mothers with hepatitis B virus infection

Συγγραφείς: Basu Roy, R, Paulus, S, Kelly, DF, Brrang, H, Taylor, A, Parker, E, Tudor-Williams, G, Banerjee, A, Mandal, S, Ramsay, ME, Pollard, A, Savulescu, J, Wilkinson, D

Relation: https://doi.org/10.2139/ssrn.3686504

Διαθεσιμότητα: https://doi.org/10.2139/ssrn.3686504
https://ora.ox.ac.uk/objects/uuid:e0242bc2-fe51-4b8e-9574-03af3be9ecc6

A computational method for immune repertoire mining that identifies novel binders from different clonotypes, demonstrated by identifying anti-pertussis toxoid antibodies.

Συγγραφείς: Richardson, E, Galson, JD, Kellam, P, Kelly, DF, Deane, CM, Smith, SE, Palser, A, Watson, S

Relation: https://doi.org/10.1080/19420862.2020.1869406

Διαθεσιμότητα: https://doi.org/10.1080/19420862.2020.1869406
https://ora.ox.ac.uk/objects/uuid:2e515e8a-6f94-4ef3-a88d-c2562260efe1

Adult T cell leukaemia/lymphoma (ATL) in pregnancy: A UK case series.

Συγγραφείς: Motedayen Aval, L, Boullier, M, Lyall, H, Collins, GP, Ayto, R, Kelly, DF, Tedder, RS, Drysdale, SB, Taylor, GP, Cook, LB

Περιγραφή αρχείου: application/pdf

Relation: https://openaccess.sgul.ac.uk/id/eprint/114552/1/Adult%20T%20cell%20leukaemialymphoma%20%28ATL%29%20in%20pregnancy%20A%20UK%20case%20series.pdf; Motedayen Aval, L; Boullier, M; Lyall, H; Collins, GP; Ayto, R; Kelly, DF; Tedder, RS; Drysdale, SB; Taylor, GP; Cook, LB (2021) Adult T cell leukaemia/lymphoma (ATL) in pregnancy: A UK case series. EJHaem, 2 (1). pp. 131-135. ISSN 2688-6146 https://doi.org/10.1002/jha2.142 SGUL Authors: Drysdale, Simon Bruce

Διαθεσιμότητα: https://openaccess.sgul.ac.uk/id/eprint/114552/
https://openaccess.sgul.ac.uk/id/eprint/114552/1/Adult%20T%20cell%20leukaemialymphoma%20%28ATL%29%20in%20pregnancy%20A%20UK%20case%20series.pdf
https://doi.org/10.1002/jha2.142

14-year trends and resistance patterns of blood and cerebrospinal fluid cultures in children under three years old.

Συγγραφείς: Takata, J, Kelly, DF, Sadarangani, M, Jeffery, K, Drysdale, SB

Περιγραφή αρχείου: application/pdf

Relation: https://openaccess.sgul.ac.uk/id/eprint/113695/1/Journal%20of%20infection%20submission.pdf; Takata, J; Kelly, DF; Sadarangani, M; Jeffery, K; Drysdale, SB (2021) 14-year trends and resistance patterns of blood and cerebrospinal fluid cultures in children under three years old. J Infect, 83 (5). pp. 533-541. ISSN 1532-2742 https://doi.org/10.1016/j.jinf.2021.08.048 SGUL Authors: Drysdale, Simon Bruce

Διαθεσιμότητα: https://openaccess.sgul.ac.uk/id/eprint/113695/
https://openaccess.sgul.ac.uk/id/eprint/113695/1/Journal%20of%20infection%20submission.pdf
https://doi.org/10.1016/j.jinf.2021.08.048

Consensus on diagnosis and management of Cushing's disease: a guideline update

Συγγραφείς: Fleseriu, M, Auchus, R, Bancos, I, Ben-Shlomo, A, Bertherat, J, Biermasz, NR, Boguszewski, CL, Bronstein, MD, Buchfelder, M, Carmichael, JD, Casanueva, FF, Castinetti, F, Chanson, P, Findling, J, Gadelha, M, Geer, EB, Giustina, A, Grossman, A, Gurnell, M, Ho, K, Ioachimescu, AG, Kaiser, UB, Karavitaki, N, Katznelson, L, Kelly, DF, Lacroix, A, McCormack, A, Melmed, S, Molitch, M, Mortini, P, Newell-Price, J, Nieman, L, Pereira, AM, Petersenn, S, Pivonello, R, Raff, H, Reincke, M, Salvatori, R, Scaroni, C, Shimon, I, Stratakis, CA, Swearingen, B, Tabarin, A, Takahashi, Y, Theodoropoulou, M, Tsagarakis, S, Valassi, E, Varlamov, EV, Vila, G, Wass, J, Webb, SM, Zatelli, MC, Biller, BMK

Περιγραφή αρχείου: text

Relation: https://eprints.whiterose.ac.uk/id/eprint/180612/5/THELANCETDE-D-21-00487R1_Manuscript%20Clean.pdf; https://eprints.whiterose.ac.uk/id/eprint/180612/6/THELANCETDE-D-21-00487R1_Appendix.pdf; Fleseriu, M, Auchus, R, Bancos, I et al. (50 more authors) (2021) Consensus on diagnosis and management of Cushing's disease: a guideline update. The Lancet Diabetes & Endocrinology, 9 (12). pp. 847-875. ISSN: 2213-8587

Διαθεσιμότητα: https://eprints.whiterose.ac.uk/id/eprint/180612/