In-depth study of gastrointestinal motility, intestinal barrier function and secretory function in an irritable bowel syndrome post-inflammatory rat model.

Authors: Hanning N; Laboratory of Experimental Medicine and Pediatrics and Infla-Med Centre of Excellence, University of Antwerp, Universiteitsplein 1, 2610, Wilrijk, Belgium., Verboven R; Laboratory of Cell Biology and Histology, University of Antwerp, Universiteitsplein 1, 2610, Wilrijk, Belgium., Smet A; Laboratory of Experimental Medicine and Pediatrics and Infla-Med Centre of Excellence, University of Antwerp, Universiteitsplein 1, 2610, Wilrijk, Belgium., Timmermans JP; Laboratory of Cell Biology and Histology, University of Antwerp, Universiteitsplein 1, 2610, Wilrijk, Belgium., De Man JG; Laboratory of Experimental Medicine and Pediatrics and Infla-Med Centre of Excellence, University of Antwerp, Universiteitsplein 1, 2610, Wilrijk, Belgium., De Winter BY; Laboratory of Experimental Medicine and Pediatrics and Infla-Med Centre of Excellence, University of Antwerp, Universiteitsplein 1, 2610, Wilrijk, Belgium; Department of Gastroenterology and Hepatology, Antwerp University Hospital, Drie Eikenstraat 655, 2650, Edegem, Belgium. Electronic address: benedicte.dewinter@uantwerpen.be.

Source: European journal of pharmacology [Eur J Pharmacol] 2025 Oct 05; Vol. 1004, pp. 177990. Date of Electronic Publication: 2025 Jul 24.

Publication Type: Journal Article

Journal Info: Publisher: Elsevier Science Country of Publication: Netherlands NLM ID: 1254354 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-0712 (Electronic) Linking ISSN: 00142999 NLM ISO Abbreviation: Eur J Pharmacol Subsets: MEDLINE

MeSH Terms: Gastrointestinal Motility* , Intestinal Barrier Function* , Irritable Bowel Syndrome*/chemically induced , Irritable Bowel Syndrome*/physiopathology , Intestinal Secretions*, Animals ; Rats ; Disease Models, Animal ; Gastric Emptying ; Colitis/chemically induced ; Colitis/physiopathology ; Trinitrobenzenesulfonic Acid ; Rats, Sprague-Dawley ; Intestinal Mucosa/physiopathology ; Male ; In Vitro Techniques

Artesunate promotes intestinal epithelial barrier repair by facilitating HMGCS2-dependent ketogenesis in experimental ulcerative colitis model mice.

Authors: Wang G; Department of Histology and Embryology, School of Basic Medical Sciences, Capital Medical University, Beijing 100069, China; School of Basic Medical Sciences, Wenzhou Medical University, Wenzhou 325000, China., Han L; Department of Histology and Embryology, School of Basic Medical Sciences, Capital Medical University, Beijing 100069, China., Sun H; Department of Histology and Embryology, School of Basic Medical Sciences, Capital Medical University, Beijing 100069, China; Beijing Key Laboratory of Cancer Invasion and Metastasis Research, Beijing 100069, China., Sun T; Department of Histology and Embryology, School of Basic Medical Sciences, Capital Medical University, Beijing 100069, China; Beijing Key Laboratory of Cancer Invasion and Metastasis Research, Beijing 100069, China., Wu B; Department of Histology and Embryology, School of Basic Medical Sciences, Capital Medical University, Beijing 100069, China; Beijing Key Laboratory of Cancer Invasion and Metastasis Research, Beijing 100069, China., Cheng X; Department of Histology and Embryology, School of Basic Medical Sciences, Capital Medical University, Beijing 100069, China., Yang S; Department of Histology and Embryology, School of Basic Medical Sciences, Capital Medical University, Beijing 100069, China; Beijing Key Laboratory of Cancer Invasion and Metastasis Research, Beijing 100069, China. Electronic address: yangshu@ccmu.edu.cn., Zhou D; Department of Histology and Embryology, School of Basic Medical Sciences, Capital Medical University, Beijing 100069, China; Beijing Key Laboratory of Cancer Invasion and Metastasis Research, Beijing 100069, China. Electronic address: zhouds08@ccmu.edu.cn.

Source: International immunopharmacology [Int Immunopharmacol] 2025 Sep 23; Vol. 162, pp. 115152. Date of Electronic Publication: 2025 Jul 03.

Publication Type: Journal Article

Journal Info: Publisher: Elsevier Science Country of Publication: Netherlands NLM ID: 100965259 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1878-1705 (Electronic) Linking ISSN: 15675769 NLM ISO Abbreviation: Int Immunopharmacol Subsets: MEDLINE

MeSH Terms: Artesunate*/pharmacology , Intestinal Barrier Function*/drug effects , Hydroxymethylglutaryl-CoA Synthase*/metabolism , Colitis, Ulcerative*/drug therapy, Animals ; Mice ; Disease Models, Animal ; TOR Serine-Threonine Kinases/metabolism ; Colon/cytology ; Colon/drug effects ; Epithelial Cells/drug effects ; Male ; Mice, Inbred C57BL ; Humans ; Cell Line ; AMP-Activated Protein Kinases/metabolism

Recent evolution of the developing human intestine affects metabolic and barrier functions.

Authors: Yu Q; Institute of Human Biology (IHB), Roche Pharma Research and Early Development, Roche Innovation Center Basel, Basel, Switzerland.; Institute of Molecular and Clinical Ophthalmology Basel, Basel, Switzerland., Kilik U; Institute of Human Biology (IHB), Roche Pharma Research and Early Development, Roche Innovation Center Basel, Basel, Switzerland.; Institute of Molecular and Clinical Ophthalmology Basel, Basel, Switzerland.; Biozentrum, University of Basel, Basel, Switzerland., Secchia S; Institute of Human Biology (IHB), Roche Pharma Research and Early Development, Roche Innovation Center Basel, Basel, Switzerland., Adam L; Institute of Human Biology (IHB), Roche Pharma Research and Early Development, Roche Innovation Center Basel, Basel, Switzerland.; Department of Biosystems Science and Engineering, ETH Zürich, Basel, Switzerland., Tsai YH; Department of Cell and Developmental Biology, University of Michigan Medical School, Ann Arbor, MI, USA., Fauci C; Department of Molecular Genetics and Microbiology, Duke University School of Medicine, Durham, NC, USA., Janssens J; Department of Biosystems Science and Engineering, ETH Zürich, Basel, Switzerland., Childs CJ; Department of Cell and Developmental Biology, University of Michigan Medical School, Ann Arbor, MI, USA., Walton KD; Department of Cell and Developmental Biology, University of Michigan Medical School, Ann Arbor, MI, USA., López-Sandoval R; Institute of Human Biology (IHB), Roche Pharma Research and Early Development, Roche Innovation Center Basel, Basel, Switzerland.; Department of Biosystems Science and Engineering, ETH Zürich, Basel, Switzerland., Wu A; Department of Cell and Developmental Biology, University of Michigan Medical School, Ann Arbor, MI, USA., Almató Bellavista M; Institute of Human Biology (IHB), Roche Pharma Research and Early Development, Roche Innovation Center Basel, Basel, Switzerland., Huang S; Department of Cell and Developmental Biology, University of Michigan Medical School, Ann Arbor, MI, USA., Steiner CA; Department of Cell and Developmental Biology, University of Michigan Medical School, Ann Arbor, MI, USA.; Division of Gastroenterology and Hepatology, Department of Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO, USA., Throm Y; Institute of Human Biology (IHB), Roche Pharma Research and Early Development, Roche Innovation Center Basel, Basel, Switzerland., Boyle MJ; Department of Genetics, Yale School of Medicine, New Haven, CT, USA., He Z; Department of Biosystems Science and Engineering, ETH Zürich, Basel, Switzerland., Beumer J; Institute of Human Biology (IHB), Roche Pharma Research and Early Development, Roche Innovation Center Basel, Basel, Switzerland., Treutlein B; Department of Biosystems Science and Engineering, ETH Zürich, Basel, Switzerland., Lowe CB; Department of Molecular Genetics and Microbiology, Duke University School of Medicine, Durham, NC, USA., Spence JR; Department of Cell and Developmental Biology, University of Michigan Medical School, Ann Arbor, MI, USA.; Division of Gastroenterology and Hepatology, Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, MI, USA.; Department of Biomedical Engineering, University of Michigan College of Engineering, Ann Arbor, MI, USA., Camp JG; Institute of Human Biology (IHB), Roche Pharma Research and Early Development, Roche Innovation Center Basel, Basel, Switzerland.; Institute of Molecular and Clinical Ophthalmology Basel, Basel, Switzerland.; Biozentrum, University of Basel, Basel, Switzerland.

Source: Science (New York, N.Y.) [Science] 2025 Aug 21; Vol. 389 (6762), pp. eadr8628. Date of Electronic Publication: 2025 Aug 21.

Publication Type: Journal Article

Journal Info: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 0404511 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1095-9203 (Electronic) Linking ISSN: 00368075 NLM ISO Abbreviation: Science Subsets: MEDLINE

MeSH Terms: Biological Evolution* , Intestinal Mucosa*/metabolism , Intestinal Mucosa*/immunology , Intestinal Mucosa*/growth & development , Adaptation, Biological*/genetics , Intestinal Barrier Function*/genetics, Animals ; Humans ; Mice ; Evolution, Molecular ; Lactase/genetics ; Lactase/metabolism ; Lipid Metabolism/genetics ; Organoids/metabolism ; Pan troglodytes ; Xenobiotics/metabolism ; Enhancer Elements, Genetic

Farnesoid X receptor inhibits proinflammatory cytokine-induced epithelial necroptosis in vitro: implications for preservation of intestinal barrier function.

Authors: Curley CE; School of Pharmacy and Biomolecular Sciences, Royal College of Surgeons in Ireland, Dublin, Ireland., Lajczak-McGinley NK; School of Pharmacy and Biomolecular Sciences, Royal College of Surgeons in Ireland, Dublin, Ireland., Adorini L; Intercept Pharmaceuticals, San Diego, California, United States., Ní Chonghaile T; Department of Physiology and Medical Physics, Royal College of Surgeons in Ireland, Dublin, Ireland., Keely SJ; School of Pharmacy and Biomolecular Sciences, Royal College of Surgeons in Ireland, Dublin, Ireland.

Source: American journal of physiology. Gastrointestinal and liver physiology [Am J Physiol Gastrointest Liver Physiol] 2025 Aug 01; Vol. 329 (2), pp. G261-G269. Date of Electronic Publication: 2025 Jun 26.

Publication Type: Journal Article

Journal Info: Publisher: American Physiological Society Country of Publication: United States NLM ID: 100901227 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1522-1547 (Electronic) Linking ISSN: 01931857 NLM ISO Abbreviation: Am J Physiol Gastrointest Liver Physiol Subsets: MEDLINE

MeSH Terms: Intestinal Barrier Function* , Necroptosis* , Cytokines*/metabolism , Receptors, Cytoplasmic and Nuclear*/metabolism , Intestinal Mucosa*/pathology, Animals ; Mice ; Interferon-gamma/metabolism ; Tumor Necrosis Factor-alpha/metabolism ; Caspase 3/metabolism ; Receptor-Interacting Protein Serine-Threonine Kinases/metabolism ; Mice, Inbred C57BL ; Male

Inhibition of FKBP5 Alleviates Inflammation and Intestinal Barrier Dysfunction in Sepsis.

Authors: Li J; Department of Critical Care Medicine, First Affiliated Hospital of Xinjiang Medical University, Urumqi, People's Republic of China., Apizi A; Department of Critical Care Medicine, First Affiliated Hospital of Xinjiang Medical University, Urumqi, People's Republic of China., Song T; Department of Critical Care Medicine, First Affiliated Hospital of Xinjiang Medical University, Urumqi, People's Republic of China., Kamilijiang P; Department of Critical Care Medicine, First Affiliated Hospital of Xinjiang Medical University, Urumqi, People's Republic of China., Yu X; Department of Critical Care Medicine, First Affiliated Hospital of Xinjiang Medical University, Urumqi, People's Republic of China., Chai R; Department of Critical Care Medicine, First Affiliated Hospital of Xinjiang Medical University, Urumqi, People's Republic of China., Yu Z; Department of Critical Care Medicine, First Affiliated Hospital of Xinjiang Medical University, Urumqi, People's Republic of China.

Source: Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research [J Interferon Cytokine Res] 2025 Aug; Vol. 45 (8), pp. 290-299. Date of Electronic Publication: 2025 Jun 04.

Publication Type: Journal Article

Journal Info: Publisher: Mary Ann Liebert Country of Publication: United States NLM ID: 9507088 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1557-7465 (Electronic) Linking ISSN: 10799907 NLM ISO Abbreviation: J Interferon Cytokine Res Subsets: MEDLINE

MeSH Terms: NF-kappa B*/metabolism , Sepsis*/genetics , Sepsis*/physiopathology , Tacrolimus Binding Proteins*/genetics , Intestinal Barrier Function*, Animals ; Mice ; Gene Knockdown Techniques ; Inflammation ; Caco-2 Cells ; Humans ; Apoptosis ; Signal Transduction

Evaluating the effects of zinc hydroxychloride on intestinal barrier permeability and biomarkers of inflammation and metabolism during and following heat stress.

Authors: Rodriguez-Jimenez S; Department of Animal Science, Iowa State University, Ames, IA 50011., Mayorga EJ; Department of Animal Science, Iowa State University, Ames, IA 50011., Abeyta MA; Department of Animal Science, Iowa State University, Ames, IA 50011., Goetz BM; Department of Animal Science, Iowa State University, Ames, IA 50011., Opgenorth J; Department of Animal Science, Iowa State University, Ames, IA 50011., Kvidera SK; Selko USA, Indianapolis, IN 46241., McCarthy MM; Selko USA, Indianapolis, IN 46241., Griswold KE; Selko USA, Indianapolis, IN 46241., Baumgard LH; Department of Animal Science, Iowa State University, Ames, IA 50011. Electronic address: baumgard@iastate.edu.

Source: Journal of dairy science [J Dairy Sci] 2025 Jul; Vol. 108 (7), pp. 7800-7814. Date of Electronic Publication: 2025 May 08.

Publication Type: Journal Article

Journal Info: Publisher: American Dairy Science Association Country of Publication: United States NLM ID: 2985126R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1525-3198 (Electronic) Linking ISSN: 00220302 NLM ISO Abbreviation: J Dairy Sci Subsets: MEDLINE

MeSH Terms: Cattle*/physiology , Heat-Shock Response* , Intestinal Barrier Function*, Animals ; Female ; Biomarkers ; Diet/veterinary ; Dietary Supplements ; Hot Temperature ; Inflammation/veterinary ; Lactation ; Milk/metabolism ; Permeability/drug effects ; Zinc

Biomarkers of intestinal permeability are linked to incident cardiovascular diseases and cardiovascular events: a review of prospective studies.

Authors: Quirk AR; Department of Nutrition and Health Science, Ball State University, Muncie, Indiana, United States., Schifferer JK; Department of Nutrition and Health Science, Ball State University, Muncie, Indiana, United States., Maki KA; Translational Biobehavioral and Health Disparities Branch, National Institutes of Health Clinical Center, Bethesda, Maryland, United States., Robinson AT; Department of Kinesiology, School of Public Health, Indiana University, Bloomington, Indiana, United States., Keirns BH; Department of Nutrition and Health Science, Ball State University, Muncie, Indiana, United States.

Source: American journal of physiology. Gastrointestinal and liver physiology [Am J Physiol Gastrointest Liver Physiol] 2025 Jul 01; Vol. 329 (1), pp. G79-G87. Date of Electronic Publication: 2025 May 19.

Publication Type: Journal Article; Review

Journal Info: Publisher: American Physiological Society Country of Publication: United States NLM ID: 100901227 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1522-1547 (Electronic) Linking ISSN: 01931857 NLM ISO Abbreviation: Am J Physiol Gastrointest Liver Physiol Subsets: MEDLINE

MeSH Terms: Intestinal Barrier Function* , Cardiovascular Diseases*/physiopathology , Biomarkers*, Humans ; Renal Insufficiency, Chronic/physiopathology

Bifidobacterium breve HH079 alleviates early-life antibiotic-exposed colon dysbiosis in mice by restoring the gut microbiota and gut barrier function.

Authors: Gu Z; School of Food Science and Engineering, Overseas Expertise Introduction Center for Discipline Innovation of Food Nutrition and Human Health, South China University of Technology, Guangzhou 510640, China. zhangb@scut.edu.cn., Lu Z; H&H Group, H&H Research, Global Research and Technology Center, Guangzhou 510700, China. erin.liu@hh.global., Wu JY; Research Institute for Future Food, Department of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong, China., Xie Z; School of Food Science and Engineering, Overseas Expertise Introduction Center for Discipline Innovation of Food Nutrition and Human Health, South China University of Technology, Guangzhou 510640, China. zhangb@scut.edu.cn., Hu R; H&H Group, H&H Research, Global Research and Technology Center, Guangzhou 510700, China. erin.liu@hh.global., Huang Q; School of Food Science and Engineering, Overseas Expertise Introduction Center for Discipline Innovation of Food Nutrition and Human Health, South China University of Technology, Guangzhou 510640, China. zhangb@scut.edu.cn., Liu F; H&H Group, H&H Research, Global Research and Technology Center, Guangzhou 510700, China. erin.liu@hh.global., Zhang B; School of Food Science and Engineering, Overseas Expertise Introduction Center for Discipline Innovation of Food Nutrition and Human Health, South China University of Technology, Guangzhou 510640, China. zhangb@scut.edu.cn.; Sino-Singapore International Research Institute, Guangzhou 510555, China.

Source: Food & function [Food Funct] 2025 May 19; Vol. 16 (10), pp. 3833-3847. Date of Electronic Publication: 2025 May 19.

Publication Type: Journal Article

Journal Info: Publisher: Royal Society of Chemistry Country of Publication: England NLM ID: 101549033 Publication Model: Electronic Cited Medium: Internet ISSN: 2042-650X (Electronic) Linking ISSN: 20426496 NLM ISO Abbreviation: Food Funct Subsets: MEDLINE

MeSH Terms: Bifidobacterium breve*/drug effects , Anti-Bacterial Agents*/chemistry , Anti-Bacterial Agents*/pharmacology , Gene Expression Regulation, Bacterial*/drug effects , Dysbiosis*/drug therapy , Dysbiosis*/microbiology , Gastrointestinal Microbiome*/drug effects , Intestinal Barrier Function*/drug effects , Colon*/drug effects , Colon*/metabolism , Colon*/microbiology , Colon*/pathology, Acetates/metabolism ; Mice, Inbred C57BL ; Neomycin/pharmacology ; Ampicillin/pharmacology ; Macrophages/drug effects ; Macrophages/microbiology ; Signal Transduction/drug effects ; NF-kappa B/metabolism ; Innate Immunity Recognition ; Animals ; Mice

HFD-induced LPS translocation and elevated blood lipids exacerbated the inflammatory response in allergic rhinitis.

Authors: Peng S; Department of Pharmacy, The First Affiliated Hospital of Chongqing Medical University, Chongqing, 400016, China., Cai X; Department of Pharmacy, The First Affiliated Hospital of Chongqing Medical University, Chongqing, 400016, China., Tang J; Department of Pharmacy, The First Affiliated Hospital of Chongqing Medical University, Chongqing, 400016, China., Huang J; Department of Pharmacy, The First Affiliated Hospital of Chongqing Medical University, Chongqing, 400016, China., Zhao X; Department of Pharmacy, The First Affiliated Hospital of Chongqing Medical University, Chongqing, 400016, China., Huang X; Department of Pharmacy, The People's Hospital of Kaizhou District, Chongqing, 405400, China., Li J; Department of Pharmacy, The First Affiliated Hospital of Chongqing Medical University, Chongqing, 400016, China. zpfirst@sina.com.

Source: Scientific reports [Sci Rep] 2025 Apr 15; Vol. 15 (1), pp. 12931. Date of Electronic Publication: 2025 Apr 15.

Publication Type: Journal Article

Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE

MeSH Terms: Rhinitis, Allergic*/etiology , Rhinitis, Allergic*/pathology , Diet, High-Fat*/adverse effects , Intestinal Barrier Function*/immunology , NLR Family, Pyrin Domain-Containing 3 Protein*/metabolism , NF-kappa B*/metabolism , Nasal Mucosa*/immunology , Nasal Mucosa*/metabolism , Nasal Mucosa*/pathology, Rats, Wistar ; Humans ; Male ; Female ; Animals ; Rats ; Cell Line, Tumor ; Ovalbumin/immunology ; Palmitic Acid ; Lipid Metabolism/immunology ; Inflammasomes/metabolism ; Nasal Lavage Fluid/immunology ; Lipids/blood ; Lipopolysaccharides/blood ; Inflammation/blood ; Cytokines/blood ; Colon/immunology ; Colon/metabolism ; Macrophages/immunology ; Macrophages/metabolism

L6H21 stabilizing gut barrier improves EtOH-LPS-induced hepatic steatosis and injury in mice.

Authors: Ren L; Department of Gastroenterology, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, 710061, China., Kong X; School of Basic Medical Sciences, Institute of Hypoxia Research, Wenzhou Medical University, Wenzhou, 325035, China., Mi C; Department of Gastroenterology, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, 710061, China., Li F; Department of Pharmacology & Toxicology, University of Louisville School of Medicine, Louisville, KY, USA., Shao T; School of Basic Medical Sciences, Institute of Hypoxia Research, Wenzhou Medical University, Wenzhou, 325035, China., Hao Z; Department of Rheumatology, The First Affiliated Hospital of Xi'an Jiaotong University, No. 277, West Yanta Road, Xi'an, 710061, China. ZMinghao2580@163.com.

Source: Journal of molecular histology [J Mol Histol] 2025 Apr 03; Vol. 56 (2), pp. 127. Date of Electronic Publication: 2025 Apr 03.

Publication Type: Journal Article

Journal Info: Publisher: Springer Netherlands Country of Publication: Netherlands NLM ID: 101193653 Publication Model: Electronic Cited Medium: Internet ISSN: 1567-2387 (Electronic) Linking ISSN: 15672379 NLM ISO Abbreviation: J Mol Histol Subsets: MEDLINE

MeSH Terms: Chemical and Drug Induced Liver Injury*/drug therapy , Chemical and Drug Induced Liver Injury*/metabolism , Chemical and Drug Induced Liver Injury*/pathology , Chalcones*/pharmacology , Chalcones*/therapeutic use , Fatty Liver*/chemically induced , Fatty Liver*/drug therapy , Fatty Liver*/metabolism , Fatty Liver*/microbiology , Ileum*/drug effects , Ileum*/metabolism , Intestinal Barrier Function*/drug effects, Male ; Animals ; Mice ; Mice, Inbred C57BL ; Ethanol/pharmacology ; Lipopolysaccharides/pharmacology ; Reactive Oxygen Species/metabolism

Odoribacter splanchnicus-derived extracellular vesicles alleviate inflammatory bowel disease by modulating gastrointestinal inflammation and intestinal barrier function via the NLRP3 inflammasome suppression.

Authors: Zhuang J; Department of Colorectal Surgery, The First Affiliated Hospital of Fujian Medical University, 20th, Chazhong Road, Fuzhou, Fujian Province, 350005, P. R. China., Zhuang Z; Department of Colorectal Surgery, The First Affiliated Hospital of Fujian Medical University, 20th, Chazhong Road, Fuzhou, Fujian Province, 350005, P. R. China., Chen B; Department of Colorectal Surgery, The First Affiliated Hospital of Fujian Medical University, 20th, Chazhong Road, Fuzhou, Fujian Province, 350005, P. R. China., Yang Y; Department of Colorectal Surgery, The First Affiliated Hospital of Fujian Medical University, 20th, Chazhong Road, Fuzhou, Fujian Province, 350005, P. R. China., Chen H; Department of Colorectal Surgery, The First Affiliated Hospital of Fujian Medical University, 20th, Chazhong Road, Fuzhou, Fujian Province, 350005, P. R. China. 18259056002@163.com., Guan G; Department of Colorectal Surgery, The First Affiliated Hospital of Fujian Medical University, 20th, Chazhong Road, Fuzhou, Fujian Province, 350005, P. R. China. fjxhggx@163.com.

Source: Molecular medicine (Cambridge, Mass.) [Mol Med] 2025 Feb 11; Vol. 31 (1), pp. 56. Date of Electronic Publication: 2025 Feb 11.

Publication Type: Journal Article

Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 9501023 Publication Model: Electronic Cited Medium: Internet ISSN: 1528-3658 (Electronic) Linking ISSN: 10761551 NLM ISO Abbreviation: Mol Med Subsets: MEDLINE

MeSH Terms: Bacteroidetes*/chemistry , NLR Family, Pyrin Domain-Containing 3 Protein*/genetics , NLR Family, Pyrin Domain-Containing 3 Protein*/metabolism , Inflammasomes*/genetics , Inflammasomes*/metabolism , Inflammatory Bowel Diseases*/chemically induced , Inflammatory Bowel Diseases*/genetics , Inflammatory Bowel Diseases*/metabolism , Inflammatory Bowel Diseases*/pathology , Extracellular Vesicles*/chemistry , Extracellular Vesicles*/metabolism , Intestinal Barrier Function*, Male ; Animals ; Mice ; Mice, Inbred C57BL ; Dextran Sulfate/toxicity

SCR Organism: Odoribacter splanchnicus

Inhibition of miR-142-3p promotes intestinal epithelial proliferation and barrier function after ischemia/reperfusion injury by targeting FoxM1.

Authors: Wang Y; Department of Gastroenterology Surgery, the Central Hospital of Dalian University of Technology (Dalian Municipal Central Hospital), No. 826 of Southwest Road Shahekou District, Dalian, 116033, People's Republic of China.; Department of Graduate School, Dalian Medical University, Dalian, 116044, People's Republic of China., Jia Z; Department of Gastroenterology Surgery, the Central Hospital of Dalian University of Technology (Dalian Municipal Central Hospital), No. 826 of Southwest Road Shahekou District, Dalian, 116033, People's Republic of China.; Department of Graduate School, Dalian Medical University, Dalian, 116044, People's Republic of China., Zheng M; Department of Gastroenterology Surgery, the Central Hospital of Dalian University of Technology (Dalian Municipal Central Hospital), No. 826 of Southwest Road Shahekou District, Dalian, 116033, People's Republic of China.; Department of Graduate School, Dalian Medical University, Dalian, 116044, People's Republic of China., Wang P; Department of Gastroenterology Surgery, the Central Hospital of Dalian University of Technology (Dalian Municipal Central Hospital), No. 826 of Southwest Road Shahekou District, Dalian, 116033, People's Republic of China.; Department of Graduate School, Dalian Medical University, Dalian, 116044, People's Republic of China., Gao J; Department of Gastroenterology Surgery, the Central Hospital of Dalian University of Technology (Dalian Municipal Central Hospital), No. 826 of Southwest Road Shahekou District, Dalian, 116033, People's Republic of China.; Department of Graduate School, Dalian Medical University, Dalian, 116044, People's Republic of China., Zhang X; Department of Gastroenterology Surgery, the Central Hospital of Dalian University of Technology (Dalian Municipal Central Hospital), No. 826 of Southwest Road Shahekou District, Dalian, 116033, People's Republic of China., Zhou T; Department of Neurology, The First Affiliated Hospital of Dalian Medical University, Dalian, 116011, China., Zu G; Department of Gastroenterology Surgery, the Central Hospital of Dalian University of Technology (Dalian Municipal Central Hospital), No. 826 of Southwest Road Shahekou District, Dalian, 116033, People's Republic of China. zushanghai@163.com.

Source: Molecular and cellular biochemistry [Mol Cell Biochem] 2025 Feb; Vol. 480 (2), pp. 1121-1135. Date of Electronic Publication: 2024 May 31.

Publication Type: Journal Article

Journal Info: Publisher: Springer Country of Publication: Netherlands NLM ID: 0364456 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1573-4919 (Electronic) Linking ISSN: 03008177 NLM ISO Abbreviation: Mol Cell Biochem Subsets: MEDLINE

MeSH Terms: MicroRNAs*/antagonists & inhibitors , MicroRNAs*/genetics , Cell Proliferation* , Intestines*/cytology , Intestines*/metabolism , Epithelial Cells*/cytology , Epithelial Cells*/metabolism , Reperfusion Injury*/metabolism , Reperfusion Injury*/pathology , Forkhead Box Protein M1*/genetics , Forkhead Box Protein M1*/metabolism , Intestinal Barrier Function*, Male ; Animals ; Mice ; Mice, Inbred C57BL ; Rats ; Cell Line ; Humans

Citrobacter rodentium promotes brain cognitive dysfunction of type 2 diabetes mice by activating FXR mediated gut barrier damage.

Authors: Li Y; The Second Affiliated Hospital of Guilin Medical University, Guilin Medical University, Guilin, 541199, Guangxi, China.; Department of General Practice, The Fifth Affiliated Hospital of Southern Medical University, Guangzhou, 510900, Guangdong, China., Chen ST; The Second Affiliated Hospital of Guilin Medical University, Guilin Medical University, Guilin, 541199, Guangxi, China.; Guangxi Key Laboratory of Diabetic Systems Medicine, Guilin Medical University, Guilin, 541199, Guangxi, China., Zhang YY; Department of General Practice, The Fifth Affiliated Hospital of Southern Medical University, Guangzhou, 510900, Guangdong, China., Qin JF; The Second Affiliated Hospital of Guilin Medical University, Guilin Medical University, Guilin, 541199, Guangxi, China.; Department of General Practice, The Fifth Affiliated Hospital of Southern Medical University, Guangzhou, 510900, Guangdong, China., Zhu X; Department of General Practice, The Fifth Affiliated Hospital of Southern Medical University, Guangzhou, 510900, Guangdong, China. 1365681080@qq.com., Yin K; The Second Affiliated Hospital of Guilin Medical University, Guilin Medical University, Guilin, 541199, Guangxi, China. Kaiyinby@qq.com.; Department of General Practice, The Fifth Affiliated Hospital of Southern Medical University, Guangzhou, 510900, Guangdong, China. Kaiyinby@qq.com.

Source: Metabolic brain disease [Metab Brain Dis] 2025 Jan 14; Vol. 40 (1), pp. 96. Date of Electronic Publication: 2025 Jan 14.

Publication Type: Journal Article

Journal Info: Publisher: Springer Country of Publication: United States NLM ID: 8610370 Publication Model: Electronic Cited Medium: Internet ISSN: 1573-7365 (Electronic) Linking ISSN: 08857490 NLM ISO Abbreviation: Metab Brain Dis Subsets: MEDLINE

MeSH Terms: Diabetes Mellitus, Type 2*/blood , Diabetes Mellitus, Type 2*/complications , Diabetes Mellitus, Type 2*/microbiology , Cognitive Dysfunction*/drug therapy , Cognitive Dysfunction*/microbiology , Intestinal Barrier Function*/drug effects , Citrobacter rodentium* , Hyaluronic Acid*/pharmacology , Hyaluronic Acid*/therapeutic use , Viscosupplements*/pharmacology , Viscosupplements*/therapeutic use, Mice, Inbred C57BL ; Male ; Animals ; Mice ; Enterobacteriaceae Infections/blood ; Enterobacteriaceae Infections/complications ; Enterobacteriaceae Infections/microbiology ; Brain/drug effects ; Brain/metabolism ; Receptors, Cytoplasmic and Nuclear/antagonists & inhibitors ; Glycodeoxycholic Acid/pharmacology ; Glycodeoxycholic Acid/therapeutic use

Acute effects of butyrate on intestinal permeability in patients with irritable bowel syndrome assessed by a novel colonoscopy research model.

Authors: Scharf MW; Nutrition-Gut-Brain Interactions Research Centre, School of Medical Sciences, Faculty of Medicine and Health, Örebro University, Örebro, Sweden., Forsgård RA; Nutrition-Gut-Brain Interactions Research Centre, School of Medical Sciences, Faculty of Medicine and Health, Örebro University, Örebro, Sweden., Prado SBR; Nutrition-Gut-Brain Interactions Research Centre, School of Medical Sciences, Faculty of Medicine and Health, Örebro University, Örebro, Sweden., Ganda Mall JP; Nutrition-Gut-Brain Interactions Research Centre, School of Medical Sciences, Faculty of Medicine and Health, Örebro University, Örebro, Sweden.; Laboratory of Neuro-Immuno-Gastroenterology, Digestive System Research Unit, Vall d'Hebron Institut de Recerca (VHIR), Vall d'Hebron Hospital Universitari, Barcelona, Spain., Repsilber D; Nutrition-Gut-Brain Interactions Research Centre, School of Medical Sciences, Faculty of Medicine and Health, Örebro University, Örebro, Sweden., Brummer RJ; Nutrition-Gut-Brain Interactions Research Centre, School of Medical Sciences, Faculty of Medicine and Health, Örebro University, Örebro, Sweden., Marques TM; Nutrition-Gut-Brain Interactions Research Centre, School of Medical Sciences, Faculty of Medicine and Health, Örebro University, Örebro, Sweden., Wall R; Nutrition-Gut-Brain Interactions Research Centre, School of Medical Sciences, Faculty of Medicine and Health, Örebro University, Örebro, Sweden.

Source: Gut microbes [Gut Microbes] 2025 Dec; Vol. 17 (1), pp. 2545414. Date of Electronic Publication: 2025 Aug 14.

Publication Type: Clinical Study; Journal Article

Journal Info: Publisher: Taylor & Francis Country of Publication: United States NLM ID: 101495343 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1949-0984 (Electronic) Linking ISSN: 19490976 NLM ISO Abbreviation: Gut Microbes Subsets: MEDLINE

MeSH Terms: Butyrates*/pharmacology , Butyrates*/administration & dosage , Intestinal Mucosa*/drug effects , Intestinal Mucosa*/metabolism , Irritable Bowel Syndrome*/drug therapy , Irritable Bowel Syndrome*/metabolism , Irritable Bowel Syndrome*/physiopathology, Adult ; Female ; Humans ; Male ; Middle Aged ; Young Adult ; Colon/drug effects ; Colon/metabolism ; Colonoscopy ; Intestinal Barrier Function ; Permeability/drug effects

The effect of anthocyanin extract from Lycium ruthenicum Murray on intestinal barrier function in Bamei ternary pigs.

Authors: Wang W; College of Agriculture and Animal Husbandry, Qinghai University, Xining, Qinghai Province, 810016, People's Republic of China., Wu H; College of Agriculture and Animal Husbandry, Qinghai University, Xining, Qinghai Province, 810016, People's Republic of China. qhwuhua@qhu.edu.cn., Li J; College of Agriculture and Animal Husbandry, Qinghai University, Xining, Qinghai Province, 810016, People's Republic of China., Chen Z; College of Agriculture and Animal Husbandry, Qinghai University, Xining, Qinghai Province, 810016, People's Republic of China., Liu J; College of Agriculture and Animal Husbandry, Qinghai University, Xining, Qinghai Province, 810016, People's Republic of China., Xu E; College of Agriculture and Animal Husbandry, Qinghai University, Xining, Qinghai Province, 810016, People's Republic of China., Hassanin AA; Genetics Department, Faculty of Agriculture, Zagazig University, Zagazig, 44511, Egypt., Rahman SU; Department of Computer Science and Bioinformatics, Khushal Khan Khattak University, Karak, Pakistan., Chen L; College of Agriculture and Animal Husbandry, Qinghai University, Xining, Qinghai Province, 810016, People's Republic of China., Zheng R; College of Agriculture and Animal Husbandry, Qinghai University, Xining, Qinghai Province, 810016, People's Republic of China.

Source: Protoplasma [Protoplasma] 2025 Nov; Vol. 262 (6), pp. 1451-1468. Date of Electronic Publication: 2025 May 23.

Publication Type: Journal Article

Journal Info: Publisher: Springer Country of Publication: Austria NLM ID: 9806853 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1615-6102 (Electronic) Linking ISSN: 0033183X NLM ISO Abbreviation: Protoplasma Subsets: MEDLINE

MeSH Terms: Anthocyanins*/pharmacology , Anthocyanins*/chemistry , Lycium*/chemistry , Plant Extracts*/pharmacology , Plant Extracts*/chemistry , Intestinal Mucosa*/drug effects , Intestinal Mucosa*/metabolism , Intestines*/drug effects, Animals ; Swine ; Antioxidants/metabolism ; Cytokines/metabolism ; Intestinal Barrier Function

Ginsenoside Rk2 Provides Multidimensional Relief for Ulcerative Colitis by Improving Intestinal Barrier Function, Reshaping Gut Microbiota, and Regulating Th17/Treg Balance.

Authors: Tan L; School of Pharmaceutical Sciences, Jilin University, Changchun 130021, China., Li Z; School of Pharmaceutical Sciences, Jilin University, Changchun 130021, China., Wu J; School of Pharmaceutical Sciences, Jilin University, Changchun 130021, China., Liu H; School of Pharmaceutical Sciences, Jilin University, Changchun 130021, China., Yang T; School of Pharmaceutical Sciences, Jilin University, Changchun 130021, China., Wang J; School of Pharmaceutical Sciences, Jilin University, Changchun 130021, China., Liu L; School of Pharmaceutical Sciences, Jilin University, Changchun 130021, China., Geng X; School of Pharmaceutical Sciences, Jilin University, Changchun 130021, China., Liu J; School of Pharmaceutical Sciences, Jilin University, Changchun 130021, China.; Ginseng Research Institute, Jilin University, Changchun 130021, China.

Source: Journal of agricultural and food chemistry [J Agric Food Chem] 2025 Oct 08; Vol. 73 (40), pp. 25340-25357. Date of Electronic Publication: 2025 Sep 24.

Publication Type: Journal Article

Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 0374755 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-5118 (Electronic) Linking ISSN: 00218561 NLM ISO Abbreviation: J Agric Food Chem Subsets: MEDLINE

MeSH Terms: Gastrointestinal Microbiome*/drug effects , Ginsenosides*/administration & dosage , Colitis, Ulcerative*/drug therapy , Colitis, Ulcerative*/microbiology , Colitis, Ulcerative*/immunology , Colitis, Ulcerative*/genetics , Th17 Cells*/immunology , Th17 Cells*/drug effects , Intestinal Mucosa*/drug effects , Intestinal Mucosa*/immunology , Intestinal Mucosa*/microbiology , Intestinal Mucosa*/metabolism , T-Lymphocytes, Regulatory*/immunology , T-Lymphocytes, Regulatory*/drug effects, Humans ; Animals ; Male ; Caco-2 Cells ; Mice ; Mice, Inbred C57BL ; Intestinal Barrier Function

Brevibacillus laterosporus BL1 improves intestinal barrier function and immune homeostasis and modulates gut microbiota in high-fat diet-fed mice.

Authors: Weng G; Institute of Animal Science, Guangdong Academy of Agricultural Sciences, State Key Laboratory of Swine and Poultry Breeding Industry, Key Laboratory of Animal Nutrition and Feed Science in South China, Ministry of Agriculture and Rural Affairs, Guangdong Provincial Key Laboratory of Animal Breeding and Nutrition, Guangzhou, China.; Guangdong Provincial Key Laboratory of Animal Nutrition Regulation, South China Agricultural University, Guangzhou, China., Ma X; Institute of Animal Science, Guangdong Academy of Agricultural Sciences, State Key Laboratory of Swine and Poultry Breeding Industry, Key Laboratory of Animal Nutrition and Feed Science in South China, Ministry of Agriculture and Rural Affairs, Guangdong Provincial Key Laboratory of Animal Breeding and Nutrition, Guangzhou, China., Yu M; Institute of Animal Science, Guangdong Academy of Agricultural Sciences, State Key Laboratory of Swine and Poultry Breeding Industry, Key Laboratory of Animal Nutrition and Feed Science in South China, Ministry of Agriculture and Rural Affairs, Guangdong Provincial Key Laboratory of Animal Breeding and Nutrition, Guangzhou, China., Song M; Institute of Animal Science, Guangdong Academy of Agricultural Sciences, State Key Laboratory of Swine and Poultry Breeding Industry, Key Laboratory of Animal Nutrition and Feed Science in South China, Ministry of Agriculture and Rural Affairs, Guangdong Provincial Key Laboratory of Animal Breeding and Nutrition, Guangzhou, China., Liu Z; Institute of Animal Science, Guangdong Academy of Agricultural Sciences, State Key Laboratory of Swine and Poultry Breeding Industry, Key Laboratory of Animal Nutrition and Feed Science in South China, Ministry of Agriculture and Rural Affairs, Guangdong Provincial Key Laboratory of Animal Breeding and Nutrition, Guangzhou, China., Deng J; Guangdong Provincial Key Laboratory of Animal Nutrition Regulation, South China Agricultural University, Guangzhou, China., Yin Y; Guangdong Provincial Key Laboratory of Animal Nutrition Regulation, South China Agricultural University, Guangzhou, China.; Institute of Subtropical Agriculture, Chinese Academy of Sciences, Changsha, China., Deng D; Institute of Animal Science, Guangdong Academy of Agricultural Sciences, State Key Laboratory of Swine and Poultry Breeding Industry, Key Laboratory of Animal Nutrition and Feed Science in South China, Ministry of Agriculture and Rural Affairs, Guangdong Provincial Key Laboratory of Animal Breeding and Nutrition, Guangzhou, China.

Source: Journal of the science of food and agriculture [J Sci Food Agric] 2025 Oct; Vol. 105 (13), pp. 7557-7567. Date of Electronic Publication: 2025 Aug 12.

Publication Type: Journal Article

Journal Info: Publisher: John Wiley & Sons Country of Publication: England NLM ID: 0376334 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-0010 (Electronic) Linking ISSN: 00225142 NLM ISO Abbreviation: J Sci Food Agric Subsets: MEDLINE

MeSH Terms: Gastrointestinal Microbiome*/drug effects , Brevibacillus*/physiology , Probiotics*/administration & dosage , Intestinal Mucosa*/immunology , Intestinal Mucosa*/microbiology , Intestinal Mucosa*/metabolism , Intestines*/microbiology , Intestines*/immunology, Animals ; Diet, High-Fat/adverse effects ; Mice ; Mice, Inbred C57BL ; Male ; Homeostasis ; Humans ; Bacteria/classification ; Bacteria/isolation & purification ; Bacteria/genetics ; Intestinal Barrier Function

Rifaximin alleviates intestinal barrier disruption and systemic inflammation via the PXR/NFκB/MLCK pathway and modulates intestinal Lachnospiraceae abundance in heat-stroke mice.

Authors: Du L; Emergency Department, Ningbo No.2 Hospital, Ningbo 315010, China., Jiang W; Emergency Department, Ningbo Hangzhou Bay Hospital, Ningbo 315336, China., Zhu X; Emergency Department, Ningbo No.2 Hospital, Ningbo 315010, China., Zhu L; Emergency Department, Ningbo No.2 Hospital, Ningbo 315010, China., Fan Y; Burns Department, Ningbo No.2 Hospital, Ningbo 315010, China., Jiang W; Department of Intensive Care Unit, Ningbo No.2 Hospital, Ningbo 315010, China. Electronic address: 13484240543@163.com.

Source: International immunopharmacology [Int Immunopharmacol] 2024 Dec 25; Vol. 143 (Pt 2), pp. 113462. Date of Electronic Publication: 2024 Oct 29.

Publication Type: Journal Article

Journal Info: Publisher: Elsevier Science Country of Publication: Netherlands NLM ID: 100965259 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1878-1705 (Electronic) Linking ISSN: 15675769 NLM ISO Abbreviation: Int Immunopharmacol Subsets: MEDLINE

MeSH Terms: Heat Stroke*/drug therapy , Heat Stroke*/immunology , Heat Stroke*/microbiology , Heat Stroke*/pathology , Rifaximin*/pharmacology , Rifaximin*/therapeutic use , Intestinal Barrier Function*/drug effects , Intestinal Barrier Function*/immunology , Intestinal Mucosa*/drug effects , Intestinal Mucosa*/metabolism , Intestinal Mucosa*/microbiology , Intestinal Mucosa*/pathology , Signal Transduction*/drug effects , Signal Transduction*/immunology , Gastrointestinal Microbiome*/drug effects , Gastrointestinal Microbiome*/immunology , Inflammation*/drug therapy , Inflammation*/immunology , Inflammation*/microbiology , Inflammation*/pathology, Animals ; Mice ; Disease Models, Animal ; Clostridiales/isolation & purification ; Clostridiales/metabolism ; Zonula Occludens-1 Protein/metabolism ; Up-Regulation/drug effects ; Occludin/metabolism ; Pregnane X Receptor/metabolism ; Myosin-Light-Chain Kinase/metabolism ; NF-kappa B/metabolism ; Fatty Acids, Volatile/metabolism ; Butyrates/metabolism ; Eubacterium ; Caco-2 Cells ; Humans ; Gastrointestinal Agents/pharmacology ; Gastrointestinal Agents/therapeutic use

Tricobalt tetraselenide nanoparticles improve intestinal barrier function by reshaping the gut microbiota and fortifying epithelial tight junctions.

Authors: Chen Y; State Key Laboratory of Trauma and Chemical Poisoning, Institute of Combined Injury of PLA, College of Preventive Medicine, Army Medical University, Chongqing, 400038, China. wangcheng@tmmu.edu.cn., Zhao N; Institute of Materia Medica and Department of Pharmaceutics, College of Pharmacy, Army Medical University, Chongqing, 400038, China., Han S; State Key Laboratory of Trauma and Chemical Poisoning, Institute of Combined Injury of PLA, College of Preventive Medicine, Army Medical University, Chongqing, 400038, China. wangcheng@tmmu.edu.cn., Zhao G; State Key Laboratory of Trauma and Chemical Poisoning, Institute of Combined Injury of PLA, College of Preventive Medicine, Army Medical University, Chongqing, 400038, China. wangcheng@tmmu.edu.cn., Jiang Y; State Key Laboratory of Trauma and Chemical Poisoning, Institute of Combined Injury of PLA, College of Preventive Medicine, Army Medical University, Chongqing, 400038, China. wangcheng@tmmu.edu.cn., Li C; State Key Laboratory of Trauma and Chemical Poisoning, Institute of Combined Injury of PLA, College of Preventive Medicine, Army Medical University, Chongqing, 400038, China. wangcheng@tmmu.edu.cn., He Y; State Key Laboratory of Trauma and Chemical Poisoning, Institute of Combined Injury of PLA, College of Preventive Medicine, Army Medical University, Chongqing, 400038, China. wangcheng@tmmu.edu.cn., Ou Y; State Key Laboratory of Trauma and Chemical Poisoning, Institute of Combined Injury of PLA, College of Preventive Medicine, Army Medical University, Chongqing, 400038, China. wangcheng@tmmu.edu.cn., Gao J; State Key Laboratory of Trauma and Chemical Poisoning, Institute of Combined Injury of PLA, College of Preventive Medicine, Army Medical University, Chongqing, 400038, China. wangcheng@tmmu.edu.cn., Wang T; State Key Laboratory of Trauma and Chemical Poisoning, Institute of Combined Injury of PLA, College of Preventive Medicine, Army Medical University, Chongqing, 400038, China. wangcheng@tmmu.edu.cn., Zhao J; Department of Nephrology, Xinqiao Hospital, Army Medical University, Chongqing, 400037, China., Cao J; Key Lab of Medical Protection for Electromagnetic Radiation, Ministry of Education of C, Institute of Toxicology, College of Preventive Medicine, Army Medical University, hina, Chongqing, 400038, China., Chen S; State Key Laboratory of Trauma and Chemical Poisoning, Institute of Combined Injury of PLA, College of Preventive Medicine, Army Medical University, Chongqing, 400038, China. wangcheng@tmmu.edu.cn., Wang J; State Key Laboratory of Trauma and Chemical Poisoning, Institute of Combined Injury of PLA, College of Preventive Medicine, Army Medical University, Chongqing, 400038, China. wangcheng@tmmu.edu.cn., Wang C; State Key Laboratory of Trauma and Chemical Poisoning, Institute of Combined Injury of PLA, College of Preventive Medicine, Army Medical University, Chongqing, 400038, China. wangcheng@tmmu.edu.cn.

Source: Biomaterials science [Biomater Sci] 2025 Dec 02; Vol. 13 (24), pp. 6775-6790. Date of Electronic Publication: 2025 Dec 02.

Publication Type: Journal Article

Journal Info: Publisher: Royal Society of Chemistry Country of Publication: England NLM ID: 101593571 Publication Model: Electronic Cited Medium: Internet ISSN: 2047-4849 (Electronic) Linking ISSN: 20474830 NLM ISO Abbreviation: Biomater Sci Subsets: MEDLINE

MeSH Terms: Gastrointestinal Microbiome*/drug effects , Nanoparticles*/chemistry , Nanoparticles*/administration & dosage , Tight Junctions*/drug effects , Tight Junctions*/metabolism , Intestinal Mucosa*/drug effects , Intestinal Mucosa*/metabolism , Cobalt*/chemistry , Cobalt*/pharmacology , Cobalt*/administration & dosage , Organoselenium Compounds*/chemistry , Organoselenium Compounds*/pharmacology , Organoselenium Compounds*/administration & dosage, Animals ; Mice ; Mice, Inbred C57BL ; Male ; Humans ; Dextran Sulfate ; Colitis/drug therapy ; Colitis/chemically induced ; Intestinal Barrier Function

Combination of Lactiplantibacillus Plantarum ELF051 and Astragalus Polysaccharides Improves Intestinal Barrier Function and Gut Microbiota Profiles in Mice with Antibiotic-Associated Diarrhea.

Authors: Zhong B; Institute of Agro-Food Technology, Jilin Academy of Agricultural Sciences (Northeast Agricultural Research Center of China), Changchun, 130033, P.R. China.; College of Food Science and Nutritional Engineering, Jilin Agriculture Science and Technology University, Jilin, 132101, P.R. China.; Brewing Technology Innovation Center of Jilin Province, Jilin Agriculture Science and Technology University, Jilin, 132101, P.R. China., Liang W; Institute of Agro-Food Technology, Jilin Academy of Agricultural Sciences (Northeast Agricultural Research Center of China), Changchun, 130033, P.R. China.; Anshan Hospital of Traditional Chinese Medicine, Anshan, 114004, P.R. China., Zhao Y; Institute of Agro-Food Technology, Jilin Academy of Agricultural Sciences (Northeast Agricultural Research Center of China), Changchun, 130033, P.R. China., Li F; College of Food Science and Nutritional Engineering, Jilin Agriculture Science and Technology University, Jilin, 132101, P.R. China.; Brewing Technology Innovation Center of Jilin Province, Jilin Agriculture Science and Technology University, Jilin, 132101, P.R. China., Zhao Z; Institute of Agro-Food Technology, Jilin Academy of Agricultural Sciences (Northeast Agricultural Research Center of China), Changchun, 130033, P.R. China., Gao Y; Institute of Agro-Food Technology, Jilin Academy of Agricultural Sciences (Northeast Agricultural Research Center of China), Changchun, 130033, P.R. China., Yang G; Institute of Agro-Food Technology, Jilin Academy of Agricultural Sciences (Northeast Agricultural Research Center of China), Changchun, 130033, P.R. China., Li S; Institute of Agro-Food Technology, Jilin Academy of Agricultural Sciences (Northeast Agricultural Research Center of China), Changchun, 130033, P.R. China. lisy720@126.com.

Source: Probiotics and antimicrobial proteins [Probiotics Antimicrob Proteins] 2025 Dec; Vol. 17 (6), pp. 4267-4280. Date of Electronic Publication: 2024 Oct 01.

Publication Type: Journal Article

Journal Info: Publisher: Springer Country of Publication: United States NLM ID: 101484100 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1867-1314 (Electronic) Linking ISSN: 18671306 NLM ISO Abbreviation: Probiotics Antimicrob Proteins Subsets: MEDLINE

MeSH Terms: Gastrointestinal Microbiome*/drug effects , Polysaccharides*/administration & dosage , Polysaccharides*/pharmacology , Astragalus Plant*/chemistry , Diarrhea*/chemically induced , Diarrhea*/microbiology , Diarrhea*/drug therapy , Diarrhea*/therapy , Anti-Bacterial Agents*/adverse effects , Intestinal Mucosa*/drug effects , Intestinal Mucosa*/microbiology , Intestinal Mucosa*/metabolism , Lactobacillus plantarum*/physiology , Probiotics*/administration & dosage, Animals ; Mice ; Male ; Intestinal Barrier Function